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Chemical Compositional, Biological, and Safety Studies of a Novel Maple Syrup Derived Extract for Nutraceutical Applications

https://doi.org/10.1021/jf501924y

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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5‐Hydroxymethylfurfural from Black Garlic Extract Prevents TNFα‐induced Monocytic Cell Adhesion to HUVECs by Suppression of Vascular Cell Adhesion Molecule‐1 Expression, Reactive Oxygen Species Generation and NF‐κB Activation

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Effects of Maple (Acer) Plant Part Extracts on Proliferation, Apoptosis and Cell Cycle Arrest of Human Tumorigenic and Non‐tumorigenic Colon Cells

inferredcites →https://doi.org/10.1007/s00216-013-7339-6openalex-snapshot

Comparison of an HPTLC method with the Reflectoquant assay for rapid determination of 5-hydroxymethylfurfural in honey

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Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical

inferredcites →https://doi.org/10.1016/j.bmcl.2011.10.073openalex-snapshot

Maplexins, new α-glucosidase inhibitors from red maple (Acer rubrum) stems

inferredcites →https://doi.org/10.1016/j.bse.2012.04.005openalex-snapshot

Acer rubrum phenolics include A-type procyanidins and a chalcone

inferredcites →https://doi.org/10.1016/j.carbpol.2013.07.060openalex-snapshot

Immunomodulatory activities of polysaccharides isolated from Taxillus chinensis and Uncaria rhyncophylla

inferredcites →https://doi.org/10.1016/j.copbio.2014.01.010openalex-snapshot

Bioactive fungal polysaccharides as potential functional ingredients in food and nutraceuticals

inferredcites →https://doi.org/10.1016/j.jff.2011.02.004openalex-snapshot

Quebecol, a novel phenolic compound isolated from Canadian maple syrup

inferredcites →https://doi.org/10.1016/j.jff.2013.06.009openalex-snapshot

Pasteurized and sterilized maple sap as functional beverages: Chemical composition and antioxidant activities

inferredcites →https://doi.org/10.1016/j.jff.2013.09.026openalex-snapshot

Phenolic mediated anti-inflammatory properties of a maple syrup extract in RAW 264.7 murine macrophages

inferredcites →https://doi.org/10.1016/j.seppur.2004.04.003openalex-snapshot

Rapid large scale purification of ellagitannins from pomegranate husk, a by-product of the commercial juice industry

inferredcites →https://doi.org/10.1016/j.tet.2011.11.062openalex-snapshot

New maplexins F–I and phenolic glycosides from red maple (Acer rubrum) bark

inferredcites →https://doi.org/10.1016/j.tetlet.2008.01.111openalex-snapshot

1H NMR spectrum simplification of phenyl compounds containing electronegative groups by intermolecular interactions

inferredcites →https://doi.org/10.1016/s0031-9422(00)85497-7openalex-snapshot

Characterization of polysaccharides isolated from maple syrup

inferredcites →https://doi.org/10.1016/s0040-4020(01)98283-3openalex-snapshot

Circulardichroismus—IX

inferredcites →https://doi.org/10.1016/s1043-4526(08)00604-9openalex-snapshot

Chapter 4 Maple Syrup—Production, Composition, Chemistry, and Sensory Characteristics

inferredcites →https://doi.org/10.1021/ed084p1647openalex-snapshot

The Chemical Composition of Maple Syrup

inferredcites →https://doi.org/10.1021/jf00051a028openalex-snapshot

Determination of Phenolic Compound Profiles in Maple Products by High-Performance Liquid Chromatography

inferredcites →https://doi.org/10.1021/jf1033398openalex-snapshot

Maple Syrup Phytochemicals Include Lignans, Coumarins, a Stilbene, and Other Previously Unreported Antioxidant Phenolic Compounds

inferredcites →https://doi.org/10.1021/jf2011613openalex-snapshot

Further Investigation into Maple Syrup Yields 3 New Lignans, a New Phenylpropanoid, and 26 Other Phytochemicals

inferredcites →https://doi.org/10.1021/jf400298copenalex-snapshot

Rosemary (Rosmarinus officinalisL.) Extract Regulates Glucose and Lipid Metabolism by Activating AMPK and PPAR Pathways in HepG2 Cells

inferredcites →https://doi.org/10.1021/jf403280nopenalex-snapshot

Hydroxymethylfurfural: A Possible Emergent Cause of Honey Bee Mortality?

inferredcites →https://doi.org/10.1021/jf980528bopenalex-snapshot

Analysis of Furanone, Pyranone, and New Heterocyclic Colored Compounds from Sugar−Glycine Model Maillard Systems

inferredcites →https://doi.org/10.1021/np200678nopenalex-snapshot

Phenolic Glycosides from Sugar Maple (Acer saccharum) Bark

inferredcites →https://doi.org/10.1080/02773819108050269openalex-snapshot

Lignin Chromophores. III. Syntheses of Hydroxy- and Alkoxystilbenes via Aryl Migration

inferredcites →https://doi.org/10.1080/13880200701735031openalex-snapshot

High-Performance Liquid Chromatography Characterization and Identification of Antioxidant Polyphenols in Maple Syrup

inferredcites →https://doi.org/10.1089/jmf.2009.0029openalex-snapshot

Antioxidant Activity, Inhibition of Nitric Oxide Overproduction, and In Vitro Antiproliferative Effect of Maple Sap and Syrup from Acer saccharum

inferredcites →https://doi.org/10.1111/j.1365-2621.1969.tb00897.xopenalex-snapshot

Trace Components of the Flavor Fraction of Maple Syrup

inferredcites →https://doi.org/10.1248/cpb.35.570openalex-snapshot

Hypervalent iodine oxidation of .ALPHA.,.BETA.-unsaturated carbonyl compounds.

inferredcites →https://doi.org/10.1271/bbb.110532openalex-snapshot

Ingested Maple Syrup Evokes a Possible Liver-Protecting Effect—Physiologic and Genomic Investigations with Rats

inferredcites →https://doi.org/10.5344/ajev.1965.16.3.144openalex-snapshot

Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents

inferredcites →https://doi.org/10.5650/jos.62.737openalex-snapshot

Comparison of the Enhancement of Plasma Glucose Levels in Type 2 Diabetes Otsuka Long-Evans Tokushima Fatty Rats by Oral Administration of Sucrose or Maple Syrup

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Simplified Natural Sweetener Profiling by 1h Nmr Spectroscopy: Using Direct Proton Detection

inferred← citeshttps://doi.org/10.1002/mnfr.201600477openalex-snapshot

Quantitative deviating effects of maple syrup extract supplementation on the hepatic gene expression of mice fed a high‐fat diet

inferred← citeshttps://doi.org/10.1007/s11064-016-1998-6openalex-snapshot

Effects of a Standardized Phenolic-Enriched Maple Syrup Extract on β-Amyloid Aggregation, Neuroinflammation in Microglial and Neuronal Cells, and β-Amyloid Induced Neurotoxicity in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1007/s11696-017-0355-9openalex-snapshot

Process optimisation for pilot-scale production of maple bark extracts, natural sources of antioxidants, phenolics, and carbohydrates

inferred← citeshttps://doi.org/10.1016/b978-0-12-816689-5.00006-7openalex-snapshot

Honey and Syrups: Healthy and Natural Sweeteners with Functional Properties

inferred← citeshttps://doi.org/10.1016/j.bmc.2017.01.050openalex-snapshot

Synthesis and anti-inflammatory activity of isoquebecol

inferred← citeshttps://doi.org/10.1016/j.bmcl.2015.11.096openalex-snapshot

Anti-inflammatory properties of quebecol and its derivatives

inferred← citeshttps://doi.org/10.1016/j.foodchem.2017.02.043openalex-snapshot

First report on isolation of 2,3,4-trihydroxy-5-methylacetophenone from palmyra palm ( Borassus flabellifer Linn.) syrup, its antioxidant and antimicrobial properties

inferred← citeshttps://doi.org/10.1016/j.foodchem.2024.139180openalex-snapshot

Production of prebiotic enriched maple syrup through enzymatic conversion of sucrose into fructo-oligosaccharides

inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e19216openalex-snapshot

Nutritional, pharmacological, and sensory properties of maple syrup: A comprehensive review

inferred← citeshttps://doi.org/10.1016/j.indcrop.2016.06.005openalex-snapshot

Antihyperglycemic, antioxidant activities of two Acer palmatum cultivars, and identification of phenolics profile by UPLC-QTOF-MS/MS: New natural sources of functional constituents

inferred← citeshttps://doi.org/10.1016/j.jep.2016.04.021openalex-snapshot

Traditional uses, phytochemistry, and pharmacology of the genus Acer (maple): A review

inferred← citeshttps://doi.org/10.1016/j.jfca.2021.103901openalex-snapshot

Authentication and quality control determination of maple syrup: A comprehensive review

inferred← citeshttps://doi.org/10.1016/j.jff.2014.10.001openalex-snapshot

Comparative analysis of maple syrup to other natural sweeteners and evaluation of their metabolic responses in healthy rats

inferred← citeshttps://doi.org/10.1016/j.microc.2021.105969openalex-snapshot

A comprehensive review on analytical techniques to detect adulteration of maple syrup

inferred← citeshttps://doi.org/10.1016/j.phytochem.2026.115004openalex-snapshot

Metabolites and bioactivities of the Acer species with edible and medicinal values

inferred← citeshttps://doi.org/10.1016/j.phytol.2016.07.010openalex-snapshot

Six new dihydrobenzofuran lignans from the branches and leaves of Illicium wardii and their cytotoxic activities

inferred← citeshttps://doi.org/10.1021/acs.jafc.5b05432openalex-snapshot

Maple Syrup Decreases TDP-43 Proteotoxicity in a Caenorhabditis elegans Model of Amyotrophic Lateral Sclerosis (ALS)

inferred← citeshttps://doi.org/10.1021/acs.jafc.6b01381openalex-snapshot

Development and UFLC-MS/MS Characterization of a Product-Specific Standard for Phenolic Quantification of Maple-Derived Foods

inferred← citeshttps://doi.org/10.1021/acs.jafc.7b01969openalex-snapshot

Isolation, Identification, and Biological Evaluation of Phenolic Compounds from a Traditional North American Confectionery, Maple Sugar

inferred← citeshttps://doi.org/10.1021/acs.jafc.9b02664openalex-snapshot

Metabolite Profiling of Two Maple-Derived Products Using Dereplication Based on High-Performance Liquid Chromatography–Diode Array Detector–Electrospray Ionization-Time-of-Flight-Mass Spectrometry: Sugar Maple Bark and Bud Hot-Water Extracts

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Base-Mediated Cascade Aldol Addition and Fragmentation Reactions of Dihydroxyfumaric Acid and Aromatic Aldehydes: Controlling Chemodivergence via Choice of Base, Solvent, and Substituents

inferred← citeshttps://doi.org/10.1039/c6fo01360kopenalex-snapshot

Anti-glycation and anti-oxidative effects of a phenolic-enriched maple syrup extract and its protective effects on normal human colon cells

inferred← citeshttps://doi.org/10.1039/d3fo01386copenalex-snapshot

Uncovering the anti-inflammatory mechanisms of phenolic-enriched maple syrup extract in lipopolysaccharide-induced peritonitis in mice: insights from data-independent acquisition proteomics analysis

inferred← citeshttps://doi.org/10.1039/d3fo04026gopenalex-snapshot

Exploring immunoregulatory properties of a phenolic-enriched maple syrup extract through integrated proteomics and in vitro assays

inferred← citeshttps://doi.org/10.1055/a-1031-7283openalex-snapshot

Barringtogenol C-type Triterpenoid Saponins from the Stem Bark of Norway Maple (Acer Platanoides)

inferred← citeshttps://doi.org/10.1080/09168451.2015.1042833openalex-snapshot

Administration of a maple syrup extract to mitigate their hepatic inflammation induced by a high-fat diet: a transcriptome analysis

inferred← citeshttps://doi.org/10.1080/1028415x.2019.1672009openalex-snapshot

Anti-neuroinflammatory effects of a food-grade phenolic-enriched maple syrup extract in a mouse model of Alzheimer’s disease

inferred← citeshttps://doi.org/10.1093/jaoacint/qsaf029openalex-snapshot

Maple Syrup Adulteration: Fluorescence Fingerprints as a Source of Information for Enhanced Detection

inferred← citeshttps://doi.org/10.1111/dth.13426openalex-snapshot

Phenolic‐enriched maple syrup extract protects human keratinocytes against hydrogen peroxide and methylglyoxal induced cytotoxicity

inferred← citeshttps://doi.org/10.1111/jfbc.13832openalex-snapshot

Chemistry, processing, and functionality of maple food products: An updated comprehensive review

inferred← citeshttps://doi.org/10.1186/s12970-019-0273-zopenalex-snapshot

Rehydrating efficacy of maple water after exercise-induced dehydration

inferred← citeshttps://doi.org/10.1186/s12986-019-0403-2openalex-snapshot

A maple syrup extract alters lipid metabolism in obese type 2 diabetic model mice

inferred← citeshttps://doi.org/10.1371/journal.pone.0215511openalex-snapshot

Perceptions of U.S. and Canadian maple syrup producers toward climate change, its impacts, and potential adaptation measures

inferred← citeshttps://doi.org/10.1515/chem-2025-0262openalex-snapshot

Preparation and flavor-enhancing effects of porous starch inclusion materials of maple syrup extract

inferred← citeshttps://doi.org/10.17113/ftb.60.02.22.7419openalex-snapshot

Nutritional and Functional Potential of Carob Syrup Versus Date and Maple Syrup

inferred← citeshttps://doi.org/10.21448/ijsm.711952openalex-snapshot

Pharmacognostical Studies on Acer campestre L. subsp. campestre

inferred← citeshttps://doi.org/10.23860/diss-dasilva-nicholas-2019openalex-snapshot

ANTI-INFLAMMATORY EFFECTS OF POLYPHENOL-ENRICHED EXTRACTS AND THEIR GUT MICROBIAL METABOLITES

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EVALUATION OF IN VITRO ANTI-INFLAMMATORY, ANTI-DIABETIC AND ANTI-LIPOGENIC ACTIVITY OF NATURAL POLYPHENOLIC EXTRACTS AND THEIR PURE CONSTITUENTS

inferred← citeshttps://doi.org/10.23860/diss-rose-kenneth-2019openalex-snapshot

DIETARY POLYPHENOLS AND THEIR GUT MICROBIOTA METABOLITES AS POTENTIAL TREATMENTS FOR ALZHEIMER'S DISEASE

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PHYTOCHEMICAL ANALYSIS AND BIOLOGICAL EVALUATION OF MAPLE (Acer saccharum) SAP WATER

inferred← citeshttps://doi.org/10.32854/agrop.v14i7.1953openalex-snapshot

Flavonoids quantification in Acer negundo L., extracts by hplc analysis

inferred← citeshttps://doi.org/10.3389/fmicb.2023.1258394openalex-snapshot

Lignan-containing maple products inhibit Listeria monocytogenes biofilms on fresh produce

inferred← citeshttps://doi.org/10.3389/fphar.2018.00726openalex-snapshot

4-(Hydroxymethyl)catechol Extracted From Fungi in Marine Sponges Attenuates Rheumatoid Arthritis by Inhibiting PI3K/Akt/NF-κB Signaling

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Valorization of date palm sap into commercially viable products: a comprehensive account on its composition, nutritional profile, processing, value addition, and potential applications

inferred← citeshttps://doi.org/10.3390/foods12020239openalex-snapshot

What Is Authentic Maple Water? A Twelve-Month Shelf-Life Study of the Chemical Composition of Maple Water and Its Biological Activities

inferred← citeshttps://doi.org/10.3390/ijerph192013684openalex-snapshot

Maple Syrup: Chemical Analysis and Nutritional Profile, Health Impacts, Safety and Quality Control, and Food Industry Applications

inferred← citeshttps://doi.org/10.3390/ijms19020461openalex-snapshot

Evaluation of Polyphenol Anthocyanin-Enriched Extracts of Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry for Free Radical Scavenging, Reactive Carbonyl Species Trapping, Anti-Glycation, Anti-β-Amyloid Aggregation, and Microglial Neuroprotective Effects

inferred← citeshttps://doi.org/10.3390/md23110440openalex-snapshot

Structure Meets Function: Dissecting Fucoxanthin’s Bioactive Architecture

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Polymers and Chemical Composition of Hardwood and Softwood (Bark, Sapwood, and Heartwood) for Biofuel Production: A Comprehensive Review

inferred← citeshttps://doi.org/10.3892/or.2023.8616openalex-snapshot

Protein components of maple syrup as a potential resource for the development of novel anti‑colorectal cancer drugs

inferred← citeshttps://doi.org/10.4236/ajps.2018.92019openalex-snapshot

Volatiles from Acer truncatum Flowers

inferred← citeshttps://doi.org/10.47611/jsrhs.v11i3.3174openalex-snapshot

Analyzing Bacteria Growth Differences Among Home Produced and Industrially Manufactured Samples of Maple Syrup from a County in Northeast Ohio

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