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Profiling of a Prescription Drug Library for Potential Renal Drug–Drug Interactions Mediated by the Organic Cation Transporter 2
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Incidence of Adverse Drug Reactions in Hospitalized Patients
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The Effect of Cimetidine and Ranitidine Administration With Zidovudine
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In Vitro Protein Binding Behavior of Dipyridamole
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Effect of probenecid on the distribution and elimination of ciprofloxacin in humans
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Sensitive determination of free and plasma protein-bound dipyridamole by high-performance liquid chromatography
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Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance
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Exploring the Role of Different Drug Transport Routes in Permeability Screening
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Structural Requirements for Drug Inhibition of the Liver Specific Human Organic Cation Transport Protein 1
inferredcites →https://doi.org/10.1021/jm900403jopenalex-snapshot
Physicochemical Determinants of Human Renal Clearance
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Probenecid Inhibits the Metabolic and Renal Clearances of Zidovudine (AZT) in Human Volunteers
inferredcites →https://doi.org/10.1038/clpt.1992.37openalex-snapshot
Stereoselective inhibition of pindolol renal clearance by cimetidine in humans
inferredcites →https://doi.org/10.1038/clpt.2009.139openalex-snapshot
Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity
inferredcites →https://doi.org/10.1038/nrd1851openalex-snapshot
Predicting in vivo drug interactions from in vitro drug discovery data
inferredcites →https://doi.org/10.1038/nrd3028openalex-snapshot
Membrane transporters in drug development
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Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures
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Effect of Genetic Variation in the Organic Cation Transporter 1, OCT1, on Metformin Pharmacokinetics
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Effect of Human Renal Cationic Transporter Inhibition on the Pharmacokinetics of Varenicline, a New Therapy for Smoking Cessation: An In Vitro–In Vivo Study
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Effect of cimetidine and ranitidine on pharmacokinetics and pharmacodynamics of a single dose of dofetilide
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Effect of cimetidine and probenecid on pilsicainide renal clearance in humans
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A Conserved Glutamate Residue in Transmembrane Helix 10 Influences Substrate Specificity of Rabbit OCT2 (SLC22A2)
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Cloning and Characterization of Two Human Polyspecific Organic Cation Transporters
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Clinical Experience With Cidofovir in the Treatment of Cytomegalovirus Retinitis
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Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin
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Reduction of metformin renal tubular secretion by cimetidine in man.
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Clarke's Analysis of Drugs and Poisons
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Relevance of the Organic Cation Transporters 1 and 2 for Antiretroviral Drug Therapy in Human Immunodeficiency Virus Infection
inferredcites →https://doi.org/10.1124/dmd.108.023911openalex-snapshot
The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
inferredcites →https://doi.org/10.1124/jpet.107.123554openalex-snapshot
Transport of Paraquat by Human Organic Cation Transporters and Multidrug and Toxic Compound Extrusion Family
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Involvement of Human Multidrug and Toxin Extrusion 1 in the Drug Interaction between Cimetidine and Metformin in Renal Epithelial Cells
inferredcites →https://doi.org/10.1124/mol.104.008821openalex-snapshot
Subtype-Specific Affinity for Corticosterone of Rat Organic Cation Transporters rOCT1 and rOCT2 Depends on Three Amino Acids within the Substrate Binding Region
inferredcites →https://doi.org/10.1126/science.1166777openalex-snapshot
A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation
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Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients
inferredcites →https://doi.org/10.1152/ajprenal.90754.2008openalex-snapshot
Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule
inferredcites →https://doi.org/10.1158/0008-5472.can-06-0769openalex-snapshot
Organic Cation Transporters Are Determinants of Oxaliplatin Cytotoxicity
inferredcites →https://doi.org/10.1177/108705719900400206openalex-snapshot
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
inferredcites →https://doi.org/10.1186/1471-2105-6-50openalex-snapshot
Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling
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Renal clearance in drug discovery and development: molecular descriptors, drug transporters and disease state
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Gene Expression Levels and Immunolocalization of Organic Ion Transporters in the Human Kidney
inferredcites →https://doi.org/10.2165/00003088-199936020-00004openalex-snapshot
Clinical Pharmacokinetics of the Antiviral Nucleotide Analogues Cidofovir and Adefovir
inferredcites →https://doi.org/10.7326/0003-4819-108-3-502_5openalex-snapshot
Goodman and Gilman's The Pharmacological Basis of Therapeutics.
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Multidrug and Toxin Extrusion Proteins
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Population Pharmacokinetic Model of Platinum Disposition in Cancer Patients Receiving Cisplatin and Randomized to 5‐HT3 Antagonist Antiemetic Drugs
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General Overview of Organic Cation Transporters in Brain
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The Interaction of Organic Cation Transporters 1-3 and PMAT with Psychoactive Substances
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Organic Cation Transporters in Psychiatric Disorders
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Substrates and Inhibitors of Organic Cation Transporters (OCTs) and Plasma Membrane Monoamine Transporter (PMAT) and Therapeutic Implications
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In Vitro Characterization of Interactions with Drug Transporting Proteins
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Pharmaceutical Drug Interactions
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Structure and function of multidrug and toxin extrusion proteins (MATEs) and their relevance to drug therapy and personalized medicine
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Human and rat renal proximal tubule in vitro models for ADME applications
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Impact of the organic cation transporter 2 inhibitor cimetidine on the single-dose pharmacokinetics of the glucosylceramide synthase inhibitor lucerastat in healthy subjects
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MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells
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Unstirred Water Layers and the Kinetics of Organic Cation Transport
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Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K
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High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3
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In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT1A Receptor Agonist for the Treatment of Schizophrenia
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Identification of Active Compounds of Hippobroma Longiflora Extract as Anticancer: Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and Experimental Validation
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A Two-Period Open-Label, Single-Dose Crossover Study in Healthy Volunteers to Evaluate the Drug–Drug Interaction Between Cimetidine and Inhaled Extrafine CHF 5993
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The Competitive Counterflow Assay for Identifying Drugs Transported by Solute Carriers: Principle, Applications, Challenges/Limits, and Perspectives
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A Comprehensive Review of Drug–Drug Interactions with Metformin
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The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers
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Renal Drug Transporters and Drug Interactions
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.95625-3openalex-snapshot
Uptake Transporters
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Uptake Transporters
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Excretory Processes in Toxicology: Drug Transporters in Drug Development
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Protective effects of esomeprazole against cisplatin-induced ototoxicity: an in vitro and in vivo study
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Polypharmacology translates between species and phylogenetic distance: A functional, bioinformatic, and structural study on organic anion transporting polypeptides
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In vitro safety signals for potential clinical development of the anti-inflammatory pregnane X receptor agonist FKK6
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Current Advances in Studying Clinically Relevant Transporters of the Solute Carrier (SLC) Family by Connecting Computational Modeling and Data Science
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MegaTrans—machine learning models for drug transporters corresponding to the FDA guidance
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The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so
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Upscaling of a living membrane for bioartificial kidney device
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In vitro validation of an in vivo phenotyping drug cocktail for major drug transporters in humans
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Esomeprazole prevents oxaliplatin-induced peripheral neuropathy through inhibiting organic cation transporter 2 in mice
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The effects of rabeprazole on metformin pharmacokinetics and pharmacodynamics in Chinese healthy volunteers
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The role of organic cation transporter 2 inhibitor cimetidine, experimental diabetes mellitus and metformin on gabapentin pharmacokinetics in rats
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The SLC22 family with transporters of organic cations, anions and zwitterions
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Identification of ACK1 inhibitors as anticancer agents by using computer-aided drug designing
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Organic cation transporters in psychiatric and substance use disorders
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Gold nanoparticles based sensor for in vitro analysis of drug-drug interactions using imipramine and isoniazid drugs: A proof of concept approach
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Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs)
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Inhibition of organic cation transporter (OCT) activities by carcinogenic heterocyclic aromatic amines
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The Effect of Uremic Solutes on the Organic Cation Transporter 2
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In silico ADME/T modelling for rational drug design
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Computational Discovery and Experimental Validation of Inhibitors of the Human Intestinal Transporter OATP2B1
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Substrates and Inhibitors of the Organic Cation Transporter 3 and Comparison with OCT1 and OCT2
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Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1)
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Computational Approaches for Predicting Drug Interactions with Human Organic Anion Transporter 4 (OAT4)
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Identification and Quantitative Assessment of Uremic Solutes as Inhibitors of Renal Organic Anion Transporters, OAT1 and OAT3
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.7b00285openalex-snapshot
Incorporation of a Biguanide Scaffold Enhances Drug Uptake by Organic Cation Transporters 1 and 2
inferred← citeshttps://doi.org/10.1021/acs.orglett.0c02216openalex-snapshot
Ligand-Accelerated Palladium(II)-Catalyzed Enantioselective Amination of C(sp2)–H Bonds
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The Brain Exposure Efficiency (BEE) Score
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Transporter Inhibition Profile for the Antivirals Tilorone, Quinacrine and Pyronaridine
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New Machine Learning Models for Predicting the Organic Cation Transporters OCT1, OCT2, and OCT3 Uptake
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Escaping from Flatland: 3D Carborane-Based Bioisosteres of Erlotinib as Potential Anticancer Agents
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Utilization of Metal Halide Species Ambiguity to Develop Amorphous, Stabilized Pharmaceutical Agents As Ionic Liquids
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Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling
inferred← citeshttps://doi.org/10.1021/jm400966vopenalex-snapshot
Identification of Novel Substrates and Structure–Activity Relationship of Cellular Uptake Mediated by Human Organic Cation Transporters 1 and 2
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pH-Dependent Solubility and Permeability Criteria for Provisional Biopharmaceutics Classification (BCS and BDDCS) in Early Drug Discovery
inferred← citeshttps://doi.org/10.1021/mp300365topenalex-snapshot
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Rapid Measurement of Intracellular Unbound Drug Concentrations
inferred← citeshttps://doi.org/10.1021/mp400423gopenalex-snapshot
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Advances in predictive in vitro models of drug-induced nephrotoxicity
inferred← citeshttps://doi.org/10.1038/s41594-023-01017-4openalex-snapshot
Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2
inferred← citeshttps://doi.org/10.1038/s41598-017-06692-0openalex-snapshot
ADME-Space: a new tool for medicinal chemists to explore ADME properties
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Identification of dequalinium as a potent inhibitor of human organic cation transporter 2 by machine learning based QSAR model
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Computational discovery of emodin-based anthraquinones as PARP-1 inhibitors with relevance to ovarian and prostate cancer
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Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory Mechanisms
inferred← citeshttps://doi.org/10.1038/srep16702openalex-snapshot
Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations
inferred← citeshttps://doi.org/10.1038/srep38006openalex-snapshot
Pharmacological characterization of a high-affinity p-tyramine transporter in rat brain synaptosomes
inferred← citeshttps://doi.org/10.1039/9781788016414-00128openalex-snapshot
OATs and OCTs: The SLC22 Family of Organic Anion and Cation Transporters
inferred← citeshttps://doi.org/10.1039/c6md00188bopenalex-snapshot
Insights into solute carriers: physiological functions and implications in disease and pharmacokinetics
inferred← citeshttps://doi.org/10.1039/c8md00472bopenalex-snapshot
ADMET-score – a comprehensive scoring function for evaluation of chemical drug-likeness
inferred← citeshttps://doi.org/10.1073/pnas.1424313112openalex-snapshot
Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions
inferred← citeshttps://doi.org/10.1080/00498254.2016.1271160openalex-snapshot
Potent inhibition of human organic cation transporter 2 (hOCT2) by β-carboline alkaloids
inferred← citeshttps://doi.org/10.1080/00498254.2018.1442030openalex-snapshot
Interactions of organophosphorus pesticides with solute carrier (SLC) drug transporters
inferred← citeshttps://doi.org/10.1080/00498254.2026.2616247openalex-snapshot
Fluorescent dyes as functional probes for studying drug-transporting solute carriers
inferred← citeshttps://doi.org/10.1080/17460913.2026.2633082openalex-snapshot
Pharmacokinetics, quantum chemistry, and molecular modeling analysis of six potential drug candidates for Chagas disease: posaconazole, K777, phenarimol derivative, BZTS, isoxazole analog, and derivative of 4-arylaminonoline-3-carbonitrile
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Electrophysiology-Based Assays to Detect Subtype-Selective Modulation of Human Nicotinic Acetylcholine Receptors
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Drug–nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3)
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Organic Cation Transporter–Mediated Clearance of Cardiovascular Drugs
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Memantine-Associated Decrease in Renal Function and Hyperuricemia
inferred← citeshttps://doi.org/10.1097/mnh.0b013e328363ffafopenalex-snapshot
Polyspecific organic cation transporters and their biomedical relevance in kidney
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Early Discontinuation of Metformin in Individuals Treated with Inhibitors of Transporters of Metformin
inferred← citeshttps://doi.org/10.1111/fcp.12657openalex-snapshot
Inhibition of organic cation transporter 3 activity by tyrosine kinase inhibitors
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The mitochondrial fluorescent dye rhodamine 123 is a high‐affinity substrate for organic cation transporters ( OCT s) 1 and 2
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Mitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural Modification
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Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease Inhibitors
inferred← citeshttps://doi.org/10.1124/dmd.115.064956openalex-snapshot
Making Transporter Models for Drug–Drug Interaction Prediction Mobile
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Effect of Ondansetron on Metformin Pharmacokinetics and Response in Healthy Subjects
inferred← citeshttps://doi.org/10.1124/dmd.119.088781openalex-snapshot
Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake
inferred← citeshttps://doi.org/10.1124/jpet.112.191577openalex-snapshot
Molecular Determinants of Ligand Selectivity for the Human Multidrug and Toxin Extruder Proteins MATE1 and MATE2-K
inferred← citeshttps://doi.org/10.1124/jpet.113.203257openalex-snapshot
Substrate-Dependent Ligand Inhibition of the Human Organic Cation Transporter OCT2
inferred← citeshttps://doi.org/10.1124/jpet.113.204206openalex-snapshot
Substrate-Dependent Inhibition of Human MATE1 by Cationic Ionic Liquids
inferred← citeshttps://doi.org/10.1124/mol.116.105056openalex-snapshot
Lack of Influence of Substrate on Ligand Interaction with the Human Multidrug and Toxin Extruder, MATE1
inferred← citeshttps://doi.org/10.1124/mol.117.111443openalex-snapshot
Assessment of Substrate-Dependent Ligand Interactions at the Organic Cation Transporter OCT2 Using Six Model Substrates
inferred← citeshttps://doi.org/10.1124/molpharm.120.000169openalex-snapshot
Predicting Drug Interactions with Human Equilibrative Nucleoside Transporters 1 and 2 Using Functional Knockout Cell Lines and Bayesian Modeling
inferred← citeshttps://doi.org/10.1124/pr.117.015305openalex-snapshot
Trace Amines and Their Receptors
inferred← citeshttps://doi.org/10.1124/pr.118.015578openalex-snapshot
Organic Cation Transporters in Health and Disease
inferred← citeshttps://doi.org/10.1145/3459930.3469514openalex-snapshot
A value-based approach for training of classifiers with high-throughput small molecule screening data
inferred← citeshttps://doi.org/10.1152/ajprenal.00152.2019openalex-snapshot
Kinetic basis of metformin-MPP interactions with organic cation transporter OCT2
inferred← citeshttps://doi.org/10.1152/ajprenal.00422.2019openalex-snapshot
Molecular and cellular physiology of organic cation transporter 2
inferred← citeshttps://doi.org/10.1152/ajprenal.00486.2012openalex-snapshot
Multiple mechanisms of ligand interaction with the human organic cation transporter, OCT2
inferred← citeshttps://doi.org/10.1158/2767-9764.crc-22-0172openalex-snapshot
Targeting OCT2 with Duloxetine to Prevent Oxaliplatin-induced Peripheral Neurotoxicity
inferred← citeshttps://doi.org/10.1186/s12936-017-2062-yopenalex-snapshot
Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates
inferred← citeshttps://doi.org/10.1186/s13321-021-00557-5openalex-snapshot
FP-ADMET: a compendium of fingerprint-based ADMET prediction models
inferred← citeshttps://doi.org/10.1186/s40203-015-0012-3openalex-snapshot
Computational modeling to predict the functions and impact of drug transporters
inferred← citeshttps://doi.org/10.1208/s12248-013-9465-7openalex-snapshot
Organic Cation Transporter OCTs (SLC22) and MATEs (SLC47) in the Human Kidney
inferred← citeshttps://doi.org/10.1208/s12248-014-9649-9openalex-snapshot
The Poorly Membrane Permeable Antipsychotic Drugs Amisulpride and Sulpiride Are Substrates of the Organic Cation Transporters from the SLC22 Family
inferred← citeshttps://doi.org/10.1248/bpb.b19-00031openalex-snapshot
Involvement of Renal Efflux Transporter MATE1 in Renal Excretion of Flecainide
inferred← citeshttps://doi.org/10.1371/journal.pone.0052247openalex-snapshot
Transport Mechanisms and Their Pathology-Induced Regulation Govern Tyrosine Kinase Inhibitor Delivery in Rheumatoid Arthritis
inferred← citeshttps://doi.org/10.1371/journal.pone.0136451openalex-snapshot
Substrate-Dependent Inhibition of the Human Organic Cation Transporter OCT2: A Comparison of Metformin with Experimental Substrates
inferred← citeshttps://doi.org/10.1371/journal.pone.0169480openalex-snapshot
Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin
inferred← citeshttps://doi.org/10.1371/journal.pone.0202706openalex-snapshot
Efavirenz reduces renal excretion of lamivudine in rats by inhibiting organic cation transporters (OCT, Oct) and multidrug and toxin extrusion proteins (MATE, Mate)
inferred← citeshttps://doi.org/10.1515/hsz-2016-0236openalex-snapshot
Tropane alkaloids as substrates and inhibitors of human organic cation transporters of the SLC22 (OCT) and the SLC47 (MATE) families
inferred← citeshttps://doi.org/10.1515/jcim-2025-0278openalex-snapshot
In silico evaluation of bioactive compounds as potential inhibitors targeting HIF-1α/VEGFA/BACE1 pathway against Alzheimer’s disease
inferred← citeshttps://doi.org/10.1517/17425255.2012.722996openalex-snapshot
Multidrug and toxin extrusion proteins as transporters of antimicrobial drugs
inferred← citeshttps://doi.org/10.1517/17425255.2015.1053462openalex-snapshot
Nature and uses of fluorescent dyes for drug transporter studies
inferred← citeshttps://doi.org/10.1533/9781908818287.455openalex-snapshot
Organic anion, organic cation and zwitterion transporters of the SLC22 and SLC47 superfamily (OATs, OCTs, OCTNs and MATEs)
inferred← citeshttps://doi.org/10.1586/ecp.12.59openalex-snapshot
Historical overview of the rationale for the pharmacological use of prolonged-release fampridine in multiple sclerosis
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2559741/v1openalex-snapshot
Discovery of novel small molecule inhibitors targeting progranulin-sortilin: A virtual high throughput screening approach
inferred← citeshttps://doi.org/10.2147/dddt.s93449openalex-snapshot
In silico approach for the discovery of new PPARγ modulators among plant-derived polyphenols
inferred← citeshttps://doi.org/10.2174/1568026611313070007openalex-snapshot
Molecular Modeling and Ligand Docking for Solute Carrier (SLC) Transporters
inferred← citeshttps://doi.org/10.26226/morressier.57d6b2bfd462b8028d88e92copenalex-snapshot
Incorporation of a Biguanide Scaffold Enhances Drug Uptake by Organic Cation Transporters 1 and 2
inferred← citeshttps://doi.org/10.3109/00498254.2016.1158886openalex-snapshot
Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters
inferred← citeshttps://doi.org/10.3109/03602532.2011.602687openalex-snapshot
Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics
inferred← citeshttps://doi.org/10.31219/osf.io/xg9jhopenalex-snapshot
Control of metabolite efflux in microbial cell factories: current advances and future prospects
inferred← citeshttps://doi.org/10.3389/fauot.2026.1729137openalex-snapshot
Evaluation of the in vitro otoprotective potential of 4-aminopyridine for cisplatin-induced ototoxicity
inferred← citeshttps://doi.org/10.3389/fphar.2014.00231openalex-snapshot
How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion
inferred← citeshttps://doi.org/10.3389/fphar.2016.00111openalex-snapshot
Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes
inferred← citeshttps://doi.org/10.3390/ijms22126439openalex-snapshot
In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs
inferred← citeshttps://doi.org/10.3390/ijms23031472openalex-snapshot
Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells
inferred← citeshttps://doi.org/10.3390/ijms231911893openalex-snapshot
Safe and Efficient Sigma1 Ligand: A Potential Drug Candidate for Multiple Sclerosis
inferred← citeshttps://doi.org/10.3390/ijms232415866openalex-snapshot
Exacerbation of Cisplatin Cellular Toxicity by Regulation of the Human Organic Cation Transporter 2 through Angiotensin II
inferred← citeshttps://doi.org/10.3390/ijms25052922openalex-snapshot
Modulating the Activity of the Human Organic Cation Transporter 2 Emerges as a Potential Strategy to Mitigate Unwanted Toxicities Associated with Cisplatin Chemotherapy
inferred← citeshttps://doi.org/10.3390/ijms27146196openalex-snapshot
Investigation of the Potential Neuroprotective Mechanisms of Acalypha indica Against Alzheimer’s Disease by Integrated Bioinformatics Analysis
inferred← citeshttps://doi.org/10.3390/md18110582openalex-snapshot
Structural Similarities between Some Common Fluorophores Used in Biology, Marketed Drugs, Endogenous Metabolites, and Natural Products
inferred← citeshttps://doi.org/10.3390/microbiolres13040052openalex-snapshot
Xanthine Analogs Suppress Trypanosoma cruzi Infection In Vitro Using PDEs as Targets
inferred← citeshttps://doi.org/10.3390/molecules30173584openalex-snapshot
Discovery of Novel Benzamide-Based Sigma-1 Receptor Agonists with Enhanced Selectivity and Safety
inferred← citeshttps://doi.org/10.36290/med.2016.059openalex-snapshot
Overview of drug-drug interactions and risks of specific medicines prescrifed of sclerosis multiplex
inferred← citeshttps://doi.org/10.3990/1.9789036543842openalex-snapshot
Development of an upscaled bioartificial kidney
inferred← citeshttps://doi.org/10.4155/fmc-2019-0060openalex-snapshot
Carboranylanilinoquinazoline EGFR-Inhibitors: Toward ‘Lead-to-Candidate’ Stage in the Drug-Development Pipeline
inferred← citeshttps://doi.org/10.53846/goediss-1437openalex-snapshot
OCT1-mediated cellular drug uptake and interactions between drug transport and drug metabolism
inferred← citeshttps://doi.org/10.53846/goediss-4872openalex-snapshot
Interaction of hepatic uptake transporters with antineoplastic compounds and regulation of the expression of organic cation transporter 3 in renal carcinoma cells
inferred← citeshttps://doi.org/10.53846/goediss-4917openalex-snapshot
The role of membrane transporters in the pharmacokinetics of psychotropic drugs: in vitro studies with special focus on organic cation transporters
inferred← citeshttps://doi.org/10.53846/goediss-7671openalex-snapshot
Erweiterte Charakterisierung substratspezifischer Effekte genetischer Polymorphismen im organischen Kationentransporter OCT1
inferred← citeshttps://doi.org/10.6084/m9.figshare.16696290openalex-snapshot
Additional file 1 of FP-ADMET: a compendium of fingerprint-based ADMET prediction models
inferred← citeshttps://doi.org/10.70675/7e400b17ze758z46cazb379z5fa6d3d667e8openalex-snapshot
Interactions de la fumée de cigarette et ses composés avec les transporteurs membranaires dans des modèles hépatiques et non-hépatiques
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