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https://doi.org/10.2139/ssrn.4655403

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inferredcites →https://doi.org/10.1002/chem.201303623openalex-extracted
Copper‐Catalyzed Trifluoromethylation and Cyclization of Aromatic‐Sulfonyl‐Group‐Tethered Alkenes for the Construction of 1,2‐Benzothiazinane Dioxide Type Compounds
inferredcites →https://doi.org/10.1002/jps.10332openalex-extracted
Development and validation of a 96-well equilibrium dialysis apparatus for measuring plasma protein binding
inferredcites →https://doi.org/10.1006/abio.2000.4633openalex-extracted
Fluorescence-Based Assay for the Interaction of Small Molecules with the Human Renal Organic Anion Transporter 1
inferredcites →https://doi.org/10.1007/s11095-009-9896-0openalex-extracted
Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs
inferredcites →https://doi.org/10.1016/0016-5085(89)90897-4openalex-extracted
Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability
inferredcites →https://doi.org/10.1016/j.bcp.2022.115147openalex-extracted
PXR as the tipping point between innate immune response, microbial infections, and drug metabolism
inferredcites →https://doi.org/10.1016/j.bcp.2023.115797openalex-extracted
Aryl hydrocarbon receptor (AhR) and pregnane X receptor (PXR) play both distinct and common roles in the regulation of colon homeostasis and intestinal carcinogenesis
inferredcites →https://doi.org/10.1016/j.bioorg.2021.104661openalex-extracted
Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics
inferredcites →https://doi.org/10.1016/j.bmcl.2018.03.051openalex-extracted
Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-γ/FFAR1 agonists
inferredcites →https://doi.org/10.1016/j.chom.2018.05.004openalex-extracted
Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion
inferredcites →https://doi.org/10.1016/j.ejmech.2021.113665openalex-extracted
Research progress of indole compounds with potential antidiabetic activity
inferredcites →https://doi.org/10.1016/j.ijpharm.2009.09.037openalex-extracted
Identification and functional characterization of breast cancer resistance protein in human bronchial epithelial cells (Calu-3)
inferredcites →https://doi.org/10.1016/j.tips.2012.03.003openalex-extracted
Pregnane X receptor as a target for treatment of inflammatory bowel disorders
inferredcites →https://doi.org/10.1016/j.tips.2020.09.013openalex-extracted
Drug Mimicry: Promiscuous Receptors PXR and AhR, and Microbial Metabolite Interactions in the Intestine
inferredcites →https://doi.org/10.1016/j.toxlet.2019.06.004openalex-extracted
Mono-methylindoles induce CYP1A genes and inhibit CYP1A1 enzyme activity in human hepatocytes and HepaRG cells
inferredcites →https://doi.org/10.1016/j.toxlet.2020.02.010openalex-extracted
Differential activation of human pregnane X receptor PXR by isomeric mono-methylated indoles in intestinal and hepatic in vitro models
inferredcites →https://doi.org/10.1016/j.toxlet.2020.09.015openalex-extracted
Indole microbial intestinal metabolites expand the repertoire of ligands and agonists of the human pregnane X receptor
inferredcites →https://doi.org/10.1016/j.toxlet.2023.09.012openalex-extracted
Switching on/off aryl hydrocarbon receptor and pregnane X receptor activities by chemically modified tryptamines
inferredcites →https://doi.org/10.1016/s0022-3565(24)29270-3openalex-extracted
Rational Use of in Vitro P-glycoprotein Assays in Drug Discovery
inferredcites →https://doi.org/10.1016/s0022-3565(24)36999-xopenalex-extracted
The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
inferredcites →https://doi.org/10.1016/s0090-9556(24)14926-4openalex-extracted
Identification of Human Cytochrome P-450 Isoforms Involved in Metabolism of R(+)- and S(−)-Gallopamil: Utility of In Vitro Disappearance Rate
inferredcites →https://doi.org/10.1016/s0169-409x(00)00129-0openalex-extracted
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
inferredcites →https://doi.org/10.1021/acs.jcim.7b00250openalex-extracted
FAME 2: Simple and Effective Machine Learning Model of Cytochrome P450 Regioselectivity
inferredcites →https://doi.org/10.1021/acs.jmedchem.2c00946openalex-extracted
Membrane Lipids Are an Integral Part of Transmembrane Allosteric Sites in GPCRs: A Case Study of Cannabinoid CB1 Receptor Bound to a Negative Allosteric Modulator, ORG27569, and Analogs
inferredcites →https://doi.org/10.1021/jm2001629openalex-extracted
Profiling of a Prescription Drug Library for Potential Renal Drug–Drug Interactions Mediated by the Organic Cation Transporter 2
inferredcites →https://doi.org/10.1111/apt.13436openalex-extracted
Review article: the potential mechanisms of action of rifaximin in the management of inflammatory bowel diseases
inferredcites →https://doi.org/10.1124/dmd.109.030221openalex-extracted
Evaluation of 4′,6-Diamidino-2-phenylindole as a Fluorescent Probe Substrate for Rapid Assays of the Functionality of Human Multidrug and Toxin Extrusion Proteins
inferredcites →https://doi.org/10.1124/dmd.111.040758openalex-extracted
In Vitro Inhibition of the Bile Salt Export Pump Correlates with Risk of Cholestatic Drug-Induced Liver Injury in Humans
inferredcites →https://doi.org/10.1124/dmd.118.081042openalex-extracted
The Roles of Xenobiotic Receptors: Beyond Chemical Disposition
inferredcites →https://doi.org/10.1124/dmd.122.000860openalex-extracted
Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
inferredcites →https://doi.org/10.1124/mol.118.112151openalex-extracted
Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor
inferredcites →https://doi.org/10.1124/mol.51.6.913openalex-extracted
Cloning and Functional Expression of a Human Liver Organic Cation Transporter
inferredcites →https://doi.org/10.1210/er.2001-0038openalex-extracted
The Nuclear Pregnane X Receptor: A Key Regulator of Xenobiotic Metabolism
inferredcites →https://doi.org/10.15252/emmm.201911621openalex-extracted
Targeting the pregnane X receptor using microbial metabolite mimicry
inferredcites →https://doi.org/10.2174/1872213x10666161230111226openalex-extracted
Rifaximin - Chitosan Nanoparticles for Inflammatory Bowel Disease (IBD)
inferredcites →https://doi.org/10.2174/1875397301004010001openalex-extracted
Development of a Cell-Based High-Throughput Assay to Screen for Inhibitors of Organic Anion Transporting Polypeptides 1B1 and 1B3
inferredcites →https://doi.org/10.3389/fimmu.2019.01070openalex-extracted
Nuclear Receptors Regulate Intestinal Inflammation in the Context of IBD
inferredcites →https://doi.org/10.3389/fimmu.2022.969399openalex-extracted
Role of nuclear receptor PXR in immune cells and inflammatory diseases
inferredcites →https://doi.org/10.3390/ijms21072614openalex-extracted
Gut Microbial Catabolites of Tryptophan Are Ligands and Agonists of the Aryl Hydrocarbon Receptor: A Detailed Characterization
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