On the public citation graph
Novel Colchicine-Site Binders with a Cyclohexanedione Scaffold Identified through a Ligand-Based Virtual Screening Approach
0 signed · 99 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1096-987x(19961115)17:14<1653::aid-jcc7>3.0.co;2-kopenalex-snapshot
A fast method of molecular shape comparison: A simple application of a Gaussian description of molecular shape
inferredcites →https://doi.org/10.1002/cmdc.200900011openalex-snapshot
Fragment‐based Identification of Hsp90 Inhibitors
inferredcites →https://doi.org/10.1002/cncr.24975openalex-snapshot
Disrupting established tumor blood vessels
inferredcites →https://doi.org/10.1002/ddr.10023openalex-snapshot
Interaction of nocodazole with tubulin isotypes
inferredcites →https://doi.org/10.1007/s11095-012-0828-zopenalex-snapshot
An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site
inferredcites →https://doi.org/10.1007/s12575-010-9029-5openalex-snapshot
Quick and Simple Detection Technique to Assess the Binding of Antimicrotubule Agents to the Colchicine-Binding Site
inferredcites →https://doi.org/10.1016/0006-2952(76)90108-8openalex-snapshot
Molecular features of colchicine associated with antimitotic activity and inhibition of tubulin polymerization
inferredcites →https://doi.org/10.1016/j.bmc.2011.11.039openalex-snapshot
Cyclohexane 1,3-diones and their inhibition of mutant SOD1-dependent protein aggregation and toxicity in PC12 cells
inferredcites →https://doi.org/10.1016/j.canlet.2010.09.004openalex-snapshot
Targeted therapies of cancer: Angiogenesis inhibition seems not enough
inferredcites →https://doi.org/10.1016/j.cell.2011.08.039openalex-snapshot
Basic and Therapeutic Aspects of Angiogenesis
inferredcites →https://doi.org/10.1016/j.ctrv.2010.05.001openalex-snapshot
The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting Agents
inferredcites →https://doi.org/10.1016/j.drudis.2011.02.011openalex-snapshot
State-of-the-art in ligand-based virtual screening
inferredcites →https://doi.org/10.1016/j.ejmech.2012.10.001openalex-snapshot
Novel 1,4-benzoxazine and 1,4-benzodioxine inhibitors of angiogenesis
inferredcites →https://doi.org/10.1016/s0021-9258(17)40631-4openalex-snapshot
Podophyllotoxin as a probe for the colchicine binding site of tubulin.
inferredcites →https://doi.org/10.1016/s0021-9258(18)49931-0openalex-snapshot
Kinetics of dissociation of the tubulin-colchicine complex. Complete reaction scheme and comparison to thermodynamic measurements.
inferredcites →https://doi.org/10.1016/s0223-5234(03)00101-6openalex-snapshot
Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines
inferredcites →https://doi.org/10.1021/bi00091a018openalex-snapshot
Tubulin binding of two 1-deaza-7,8-dihydropteridines with different biological properties: Enantiomers NSC 613862 (S)-(-) and NSC 613863 (R)-(+)
inferredcites →https://doi.org/10.1021/bi00229a026openalex-snapshot
Roles of ring C oxygens in the binding of colchicine to tubulin
inferredcites →https://doi.org/10.1021/bi00439a038openalex-snapshot
Roles of colchicine rings B and C in the binding process to tubulin
inferredcites →https://doi.org/10.1021/bi970568topenalex-snapshot
The Active GTP- and Ground GDP-Liganded States of Tubulin Are Distinguished by the Binding of Chiral Isomers of Ethyl 5-Amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl Carbamate
inferredcites →https://doi.org/10.1021/ci00057a005openalex-snapshot
SMILES, a chemical language and information system. 1. Introduction to methodology and encoding rules
inferredcites →https://doi.org/10.1021/ci3001277openalex-snapshot
ZINC: A Free Tool to Discover Chemistry for Biology
inferredcites →https://doi.org/10.1021/jm00130a023openalex-snapshot
New anticancer agents: alterations of the carbamate group of ethyl (5-amino-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl)carbamates
inferredcites →https://doi.org/10.1021/jm00215a018openalex-snapshot
Nonsteroidal antiinflammatory agents. 1. 5-Alkoxy-3-biphenylylacetic acids and related compounds as new potential antiinflammatory agents
inferredcites →https://doi.org/10.1021/jm040163oopenalex-snapshot
A Shape-Based 3-D Scaffold Hopping Method and Its Application to a Bacterial Protein−Protein Interaction
inferredcites →https://doi.org/10.1021/jm900230jopenalex-snapshot
Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents
inferredcites →https://doi.org/10.1021/jm900818sopenalex-snapshot
Molecular Shape and Medicinal Chemistry: A Perspective
inferredcites →https://doi.org/10.1021/ml300322nopenalex-snapshot
Discovery of a Series of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion
inferredcites →https://doi.org/10.1038/bjc.1982.16openalex-snapshot
Endothelial cell proliferation as a novel approach to targeting tumour therapy
inferredcites →https://doi.org/10.1038/nature02393openalex-snapshot
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
inferredcites →https://doi.org/10.1038/nrc1317openalex-snapshot
Microtubules as a target for anticancer drugs
inferredcites →https://doi.org/10.1038/sj.bjc.6601261openalex-snapshot
Microvascular mechanisms by which the combretastatin A-4 derivative AC7700 (AVE8062) induces tumour blood flow stasis
inferredcites →https://doi.org/10.1038/sj.bjc.6606058openalex-snapshot
Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines
inferredcites →https://doi.org/10.1054/bjoc.1999.1010openalex-snapshot
Relationship of vascular maturation in breast cancer blood vessels to vascular density and metastasis, assessed by expression of a novel basement membrane component, LH39
inferredcites →https://doi.org/10.1054/bjoc.2001.1809openalex-snapshot
3D microvascular architecture of pre-cancerous lesions and invasive carcinomas of the colon
inferredcites →https://doi.org/10.1056/nejm197108122850711openalex-snapshot
Transplacental Carcinogenesis by Stilbestrol
inferredcites →https://doi.org/10.1056/nejm197111182852108openalex-snapshot
Tumor Angiogenesis: Therapeutic Implications
inferredcites →https://doi.org/10.1073/pnas.0904223106openalex-snapshot
Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
inferredcites →https://doi.org/10.1074/jbc.m110.141929openalex-snapshot
Stathmin and Interfacial Microtubule Inhibitors Recognize a Naturally Curved Conformation of Tubulin Dimers
inferredcites →https://doi.org/10.1074/jbc.m112.423905openalex-snapshot
The Role of Microtubules and Their Dynamics in Cell Migration
inferredcites →https://doi.org/10.1111/j.1365-2613.2009.00651.xopenalex-snapshot
Microtubule depolymerizing vascular disrupting agents: novel therapeutic agents for oncology and other pathologies
inferredcites →https://doi.org/10.1124/mol.106.026559openalex-snapshot
The Nucleotide Analog Cidofovir Suppresses Basic Fibroblast Growth Factor (FGF2) Expression and Signaling and Induces Apoptosis in FGF2-Overexpressing Endothelial Cells
inferredcites →https://doi.org/10.1124/mol.107.034876openalex-snapshot
Identification and Characterization of a New Tubulin-Binding Tetrasubstituted Brominated Pyrrole
inferredcites →https://doi.org/10.1158/1078-0432.416.11.2openalex-snapshot
Differentiation and Definition of Vascular-Targeted Therapies
inferredcites →https://doi.org/10.1158/1078-0432.ccr-0518-03openalex-snapshot
Comparative Preclinical Pharmacokinetic and Metabolic Studies of the Combretastatin Prodrugs Combretastatin A4 Phosphate and A1 Phosphate
inferredcites →https://doi.org/10.1182/blood.v99.6.2060openalex-snapshot
The tumor vascular targeting agent combretastatin A–4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells
inferredcites →https://doi.org/10.1517/13543784.13.9.1171openalex-snapshot
Combretastatin A4 phosphate: background and current clinical status
inferredcites →https://doi.org/10.1517/13543784.2013.759557openalex-snapshot
Vascular-disrupting agents in oncology
inferredcites →https://doi.org/10.2174/138945011798829366openalex-snapshot
Vascular Disrupting Agents (VDA) in Oncology: Advancing Towards New Therapeutic Paradigms in the Clinic
inferredcites →https://doi.org/10.3109/15563650.2010.495348openalex-snapshot
Colchicine poisoning: the dark side of an ancient drug
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4814175openalex-extracted
Discovery of Colchicine Aryne Cyclo-Adduct as a Potent Molecule for the Abrogation of Epithelial to Mesenchymal Transition Via Modulating Cell Cycle Regulatory Cdk-2 and Cdk-4 Kinases
inferred← citeshttps://doi.org/10.1002/ardp.202100425openalex-snapshot
Novel substituted 5‐methyl‐4‐acylaminoisoxazoles as antimitotic agents: Evaluation of selectivity to LNCaP cancer cells
inferred← citeshttps://doi.org/10.1002/ejoc.201600130openalex-snapshot
Synthesis of Pironetin–Dumetorine Hybrids as Tubulin Binders
inferred← citeshttps://doi.org/10.1016/j.bioorg.2023.107076openalex-snapshot
Tubulin inhibitors. Selected scaffolds and main trends in the design of novel anticancer and antiparasitic agents
inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107581openalex-snapshot
Discovery of colchicine aryne cycloadduct as a potent molecule for the abrogation of epithelial to mesenchymal transition via modulating cell cycle regulatory CDK-2 and CDK-4 kinases in breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.bmc.2015.04.055openalex-snapshot
Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.04.041openalex-snapshot
Synthesis and anticancer activity of novel aza-artemisinin derivatives
inferred← citeshttps://doi.org/10.1016/j.drudis.2021.12.001openalex-snapshot
Molecular interactions at the colchicine binding site in tubulin: An X-ray crystallography perspective
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.09.093openalex-snapshot
Synthesis and antiproliferative activity of 6-phenylaminopurines
inferred← citeshttps://doi.org/10.1016/j.ejmech.2015.05.047openalex-snapshot
Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para-nitrogen substituted isocombretastatins
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.02.049openalex-snapshot
β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.12.010openalex-snapshot
Design, synthesis and biological evaluation of 1, 4-dihydro indeno[1,2- c ] pyrazole linked oxindole analogues as potential anticancer agents targeting tubulin and inducing p53 dependent apoptosis
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.02.019openalex-snapshot
Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.03.045openalex-snapshot
Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the αT5 loop
inferred← citeshttps://doi.org/10.1016/j.ejmech.2020.112050openalex-snapshot
β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114895openalex-snapshot
Identification of novel aza-analogs of TN-16 as disrupters of microtubule dynamics through a multicomponent reaction
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.10.136openalex-snapshot
Identification of novel αβ-tubulin modulators with antiproliferative activity directed to cancer therapy using ligand and structure-based virtual screening
inferred← citeshttps://doi.org/10.1016/j.steroids.2017.06.001openalex-snapshot
Regioselective monoalkylation of 17β-estradiol for the synthesis of cytotoxic estrogens
inferred← citeshttps://doi.org/10.1016/j.steroids.2018.05.002openalex-snapshot
Synthesis, molecular modeling and biological evaluation of potent analogs of 2-methoxyestradiol
inferred← citeshttps://doi.org/10.1016/j.ymeth.2017.08.010openalex-snapshot
Function and structure-based screening of compounds, peptides and proteins to identify drug candidates
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c01775openalex-snapshot
PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5b01086openalex-snapshot
Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b00463openalex-snapshot
Blocking Blood Flow to Solid Tumors by Destabilizing Tubulin: An Approach to Targeting Tumor Growth
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b01591openalex-snapshot
N-Heterocyclic (4-Phenylpiperazin-1-yl)methanones Derived from Phenoxazine and Phenothiazine as Highly Potent Inhibitors of Tubulin Polymerization
inferred← citeshttps://doi.org/10.1021/acschembio.6b00358openalex-snapshot
Aggregated Compound Biological Signatures Facilitate Phenotypic Drug Discovery and Target Elucidation
inferred← citeshttps://doi.org/10.1021/jm500849zopenalex-snapshot
Synthesis and Biological Evaluation of Novel Millepachine Derivatives As a New Class of Tubulin Polymerization Inhibitors
inferred← citeshttps://doi.org/10.1038/s41598-018-22382-xopenalex-snapshot
High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design
inferred← citeshttps://doi.org/10.1039/c4ay02078bopenalex-snapshot
Ultra-sensitive solid substrate-room temperature phosphorimetry for colchicine detection based on its catalytic effect on H 2 O 2 oxidation of acridine yellow
inferred← citeshttps://doi.org/10.1039/c5ra26807aopenalex-snapshot
Targeting the colchicine site in tubulin through cyclohexanedione derivatives
inferred← citeshttps://doi.org/10.1039/c7ob00707hopenalex-snapshot
A new four-component reaction involving the Michael addition and the Gewald reaction, leading to diverse biologically active 2-aminothiophenes
inferred← citeshttps://doi.org/10.1039/c9dt00335eopenalex-snapshot
A platinum( iv ) prodrug to defeat breast cancer through disrupting vasculature and inhibiting metastasis
inferred← citeshttps://doi.org/10.1039/d1md00392eopenalex-snapshot
Identification and validation of novel microtubule suppressors with an imidazopyridine scaffold through structure-based virtual screening and docking
inferred← citeshttps://doi.org/10.1039/d3sc05729aopenalex-snapshot
Modular synthesis of functional libraries by accelerated SuFEx click chemistry
inferred← citeshttps://doi.org/10.1039/d5cb00321kopenalex-snapshot
Illuminating microtubule functions with small molecules: past, present and future of fluorescent tubulin-binding probes
inferred← citeshttps://doi.org/10.1055/s-0039-1690053openalex-snapshot
Synthesis of 4-Nitroisoxazoles via NO/NO2-Mediated Heterocyclization of Aryl-Substituted α,β-Unsaturated Ketones
inferred← citeshttps://doi.org/10.1111/cbdd.12507openalex-snapshot
Synthesis and Evaluation of Millepachine Amino Acid Prodrugs With Enhanced Solubility as Antitumor Agents
inferred← citeshttps://doi.org/10.1111/cbdd.13416openalex-snapshot
Targeting the Plasmodium falciparum plasmepsin V by ligand‐based virtual screening
inferred← citeshttps://doi.org/10.18632/oncotarget.9527openalex-snapshot
Antivascular and antitumor properties of the tubulin-binding chalcone TUB091
inferred← citeshttps://doi.org/10.26434/chemrxiv-2024-rs3lhopenalex-snapshot
Silicon-tethered colchicine aryne cyclo-adduct as a potent molecule for the abrogation of epithelial to mesenchymal transition via modulating cell cycle regulatory CDK-2 and CDK-4 kinases
inferred← citeshttps://doi.org/10.3390/agronomy13010202openalex-snapshot
Discovery of 3-(1-Amino-2-phenoxyethylidene)-6-methyl-2H-pyran-2,4(3H)-dione Derivatives as Novel Herbicidal Leads
inferred← citeshttps://doi.org/10.3390/molecules20033898openalex-snapshot
Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents
inferred← citeshttps://doi.org/10.3390/molecules25133052openalex-snapshot
Synthesis and Biological Evaluation of Analogs of Didehydroepiandrosterone as Potential New Anticancer Agents
inferred← citeshttps://doi.org/10.3390/molecules30163445openalex-snapshot
Design, Synthesis and Herbicidal Activity of 5-(1-Amino-4-phenoxybutylidene)barbituric Acid Derivatives Containing an Enamino Diketone Motif
inferred← citeshttps://doi.org/10.3390/ph12020056openalex-snapshot
3-Vinylazetidin-2-Ones: Synthesis, Antiproliferative and Tubulin Destabilizing Activity in MCF-7 and MDA-MB-231 Breast Cancer Cells
inferred← citeshttps://doi.org/10.3390/ph15070835openalex-snapshot
Hybridization Approach to Identify Salicylanilides as Inhibitors of Tubulin Polymerization and Signal Transducers and Activators of Transcription 3 (STAT3)
inferred← citeshttps://doi.org/10.3390/ph16071000openalex-snapshot
Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells
inferred← citeshttps://doi.org/10.4155/fmc-2020-0376openalex-snapshot
Recent Advances in Research of Colchicine Binding Site Inhibitors and Their Interaction Modes With Tubulin
inferred← citeshttps://doi.org/10.6023/cjoc202010042openalex-snapshot
Synthesis and Herbicidal Activity of 5-(1-Amino-2-phenoxyethylidene)barbituric Acid Derivatives
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.