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Discovery of (R)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/hep.22357openalex-snapshot
R1626 plus peginterferon Alfa‐2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin†
inferredcites →https://doi.org/10.1016/j.bmcl.2006.06.065openalex-snapshot
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inferredcites →https://doi.org/10.1016/s0168-8278(08)60068-9openalex-snapshot
66 POTENT ANTIVIRAL ACTIVITY OF THE HCV NUCLEOSIDE POLYMERASE INHIBITOR R7128 WITH PEG-IFN AND RIBAVIRIN: INTERIM RESULTS OF R7128 500MG BID FOR 28 DAYS
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588 IN VITRO ANTIVIRAL ACTIVITY AND PHARMACOLOGY OF IDX184, A NOVEL AND POTENT INHIBITOR OF HCV REPLICATION
inferredcites →https://doi.org/10.1021/jm0704447openalex-snapshot
Allosteric Inhibitors of Hepatitis C Polymerase: Discovery of Potent and Orally Bioavailable Carbon-Linked Dihydropyrones
inferredcites →https://doi.org/10.1038/nrd2411openalex-snapshot
The way forward in HCV treatment — finding the right path
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inferredcites →https://doi.org/10.1128/aac.01008-06openalex-snapshot
Development of a Novel Dicistronic Reporter-Selectable Hepatitis C Virus Replicon Suitable for High-Throughput Inhibitor Screening
inferredcites →https://doi.org/10.1128/jvi.77.13.7575-7581.2003openalex-snapshot
Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme
inferredcites →https://doi.org/10.1556/oh.2008.28bopenalex-snapshot
The 43rd Annual Meeting of the European Association for the Study of the Liver (EASL), Milan, Italy, April 23–27, 2008
inferredcites →https://doi.org/10.2174/187152606776056698openalex-snapshot
Nucleoside Analog Inhibitors of Hepatitis C Virus Replication
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Investigation of the hepatitis C virus RNA polymerase NS5B in solution by nuclear magnetic resonance and its interaction with intrinsically disordered domain 2 of the NS5A protein
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