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Pharmacogenetics, Drug-Metabolizing Enzymes, and Clinical Practice

https://doi.org/10.1124/pr.58.3.6

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archinte.1971.00310210075006openalex-snapshot

Adverse Reactions to Sulfisoxazole, Sulfamethoxazole, and Nitrofurantoin

inferredcites →https://doi.org/10.1001/jama.1986.03380240052027openalex-snapshot

Drug-Induced Cutaneous Reactions

inferredcites →https://doi.org/10.1001/jama.1995.03530200047035openalex-snapshot

Pharmacogenetic Explanation for Excessive β-Blockade Following Timolol Eye Drops

inferredcites →https://doi.org/10.1001/jama.256.24.3358openalex-snapshot

Drug-induced cutaneous reactions. A report from the Boston Collaborative Drug Surveillance Program on 15,438 consecutive inpatients, 1975 to 1982

inferredcites →https://doi.org/10.1001/jama.281.11.1014openalex-snapshot

Hepatotoxicity Associated With Isoniazid Preventive Therapy

inferredcites →https://doi.org/10.1001/jama.287.13.1690openalex-snapshot

Association Between CYP2C9 Genetic Variants and Anticoagulation-Related Outcomes During Warfarin Therapy

inferredcites →https://doi.org/10.1002/(sici)1096-8652(199912)62:4<251::aid-ajh10>3.0.co;2-mopenalex-snapshot

Lack of relevance of the acetylator status on dapsone response in chronic autoimmune thrombocytopenic purpura

inferredcites →https://doi.org/10.1002/(sici)1098-1004(1998)12:3<177::aid-humu5>3.0.co;2-eopenalex-snapshot

Detection of known and new mutations in the thiopurineS-methyltransferase gene by single-strand conformation polymorphism analysis

inferredcites →https://doi.org/10.1002/(sici)1099-081x(199807)19:5<309::aid-bdd108>3.0.co;2-9openalex-snapshot

The influence of plasma butyrylcholinesterase concentration on thein vitro hydrolysis of cocaine in human plasma

inferredcites →https://doi.org/10.1002/1097-0142(197504)35:4<1031::aid-cncr2820350403>3.0.co;2-nopenalex-snapshot

A double-blind comparison of intensive course 5-fluorouracil by oral vs. intravenous route in the treatment of colorectal carcinoma

inferredcites →https://doi.org/10.1002/1097-0142(19910801)68:3<499::aid-cncr2820680309>3.0.co;2-fopenalex-snapshot

Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome

inferredcites →https://doi.org/10.1002/1099-1557(200009/10)9:5<393::aid-pds519>3.0.co;2-lopenalex-snapshot

Drug metabolism genotypes and their association with adverse drug reactions in selected populations: a pilot study of methodology

inferredcites →https://doi.org/10.1002/1529-0131(199810)41:10<1858::aid-art19>3.0.co;2-8openalex-snapshot

Reduced thiopurine methyltransferase activity and development of side effects of azathioprine treatment in patients with rheumatoid arthritis

inferredcites →https://doi.org/10.1002/ajh.1094openalex-snapshot

Extreme warfarin sensitivity in siblings associated with multiple cytochrome P450 polymorphisms

inferredcites →https://doi.org/10.1002/ajmg.10602openalex-snapshot

Tardive dystonia and genetic polymorphisms of cytochrome P4502D6 and dopamine D2 and D3 receptors: A preliminary finding

inferredcites →https://doi.org/10.1002/ajmg.1320570413openalex-snapshot

Preliminary phenotypic map of chromosome 4p16 based on 4p deletions

inferredcites →https://doi.org/10.1002/art.1780300401openalex-snapshot

Low‐dose methotrexate compared with azathioprine in the treatment of rheumatoid arthritis. a twenty‐four—week controlled clinical trial

inferredcites →https://doi.org/10.1002/bmc.115openalex-snapshot

Investigation of the pharmacokinetics of celecoxib by liquid chromatography–mass spectrometry

inferredcites →https://doi.org/10.1002/cpt1972133420openalex-snapshot

Relation of hydralazine plasma concentration to dosage and hypotensive action

inferredcites →https://doi.org/10.1002/cpt197518170openalex-snapshot

Increased incidence of isoniazid hepatitis in rapid acetylators: possible relation to hydrazine metabolites

inferredcites →https://doi.org/10.1002/cpt1975185part1514openalex-snapshot

Acetylation polymorphism of sulfapyridine in patients with ulcerative colitis and Crohn's disease

inferredcites →https://doi.org/10.1002/cpt1976195part2610openalex-snapshot

Variations between individuals and populations in the acetylation of isoniazid and its significance for the treatment of pulmonary tuberculosis

inferredcites →https://doi.org/10.1002/cpt1977223251openalex-snapshot

Clinical consequences of polymorphic acetylation of basic drugs

inferredcites →https://doi.org/10.1002/cpt1977224447openalex-snapshot

Procainamide and N‐acetylprocainamide kinetics investigated simultaneously with stable isotope methodology

inferredcites →https://doi.org/10.1002/cpt1977225part1602openalex-snapshot

Monoacetylhydrazine as a metabolite of isoniazid in man

inferredcites →https://doi.org/10.1002/cpt1978235547openalex-snapshot

Metabolism of cocaine in man

inferredcites →https://doi.org/10.1002/cpt1979254464openalex-snapshot

Cocaine metabolism: Cocaine and norcocaine hydrolysis by liver and serum esterases

inferredcites →https://doi.org/10.1002/hep.1840060223openalex-snapshot

Elevated Serum Aminotransferase Induced by Isoniazid in Relation to Isoniazid Acetylator Phenotype

inferredcites →https://doi.org/10.1002/hup.394openalex-snapshot

Cytochrome P450 2D6 genotype does not predict SSRI (fluoxetine or paroxetine) induced hyponatraemia

inferredcites →https://doi.org/10.1002/hup.539openalex-snapshot

No evidence of increased adverse drug reactions in cytochrome P450 CYP2D6 poor metabolizers treated with fluoxetine or nortriptyline

inferredcites →https://doi.org/10.1002/ijc.10599openalex-snapshot

Increased risk of grade IV neutropenia after administration of 5‐fluorouracil due to a dihydropyrimidine dehydrogenase deficiency: High prevalence of the IVS14+1g>a mutation

inferredcites →https://doi.org/10.1002/j.1552-4604.1998.tb04399.xopenalex-snapshot

Five Distinct Human Cytochromes Mediate Amitriptyline N‐DemethylationIn Vitro: Dominance of CYP 2C19 and 3A4

inferredcites →https://doi.org/10.1002/j.1875-9114.1997.tb03097.xopenalex-snapshot

Impact of CYP2D6 Poor Metabolizer Phenotype on Propranolol Pharmacokinetics and Response

inferredcites →https://doi.org/10.1002/jps.2600700325openalex-snapshot

High-Performance Liquid Chromatographic Assay of Perhexiline Maleate in Plasma

inferredcites →https://doi.org/10.1002/jps.2600741003openalex-snapshot

Metabolic Fate of Phenprocoumon in Humans

inferredcites →https://doi.org/10.1002/pds.926openalex-snapshot

Thiopurine drug adverse effects in a population of New Zealand patients with inflammatory bowel disease

inferredcites →https://doi.org/10.1006/abbi.1998.0615openalex-snapshot

Characterization of CYP2C19 and CYP2C9 from Human Liver: Respective Roles in Microsomal Tolbutamide,S-Mephenytoin, and Omeprazole Hydroxylations

inferredcites →https://doi.org/10.1006/geno.1998.5379openalex-snapshot

Characterization of the Human Dihydropyrimidine Dehydrogenase Gene

inferredcites →https://doi.org/10.1007/978-1-4615-9110-8_53openalex-snapshot

Genetic Control of Tolbutamide Metabolism in Humans

inferredcites →https://doi.org/10.1007/bf00226332openalex-snapshot

Role of human liver microsomal CYP2C9 in the biotransformation of lornoxicam

inferredcites →https://doi.org/10.1007/bf00265920openalex-snapshot

The effect of quinidine on the analgesic effect of codeine

inferredcites →https://doi.org/10.1007/bf00279977openalex-snapshot

Intraindividual variation in 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute lymphoblastic leukaemia

inferredcites →https://doi.org/10.1007/bf00280070openalex-snapshot

Polymorphic flecainide disposition under conditions of uncontrolled urine flow and pH

inferredcites →https://doi.org/10.1007/bf00280071openalex-snapshot

The relationships between dose and concentration of tolbutamide and insulin and glucose responses in patients with non-insulin-dependent diabetes

inferredcites →https://doi.org/10.1007/bf00280101openalex-snapshot

Impact of environmental and genetic factors on codeine analgesia

inferredcites →https://doi.org/10.1007/bf00315282openalex-snapshot

Influence of debrisoquine hydroxylation phenotype on the pharmacokinetics of mexiletine

inferredcites →https://doi.org/10.1007/bf00316090openalex-snapshot

Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations

inferredcites →https://doi.org/10.1007/bf00316110openalex-snapshot

Clinical implications of slow sulphoxidation of thioridazine in a poor metabolizer of the debrisoquine type

inferredcites →https://doi.org/10.1007/bf00316471openalex-snapshot

Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine

inferredcites →https://doi.org/10.1007/bf00421116openalex-snapshot

The relationship between acetylator status and inhibition of monoamine oxidase, excretion of free drug and antidepressant response in depressed patients on phenelzine

inferredcites →https://doi.org/10.1007/bf00541938openalex-snapshot

Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man

inferredcites →https://doi.org/10.1007/bf00546706openalex-snapshot

Should the acetylator phenotype be determined when prescribing hydralazine for hypertension?

inferredcites →https://doi.org/10.1007/bf00558224openalex-snapshot

Quinidine inhibits the 2-hydroxylation of imipramine and desipramine but not the demethylation of imipramine

inferredcites →https://doi.org/10.1007/bf00562059openalex-snapshot

Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

inferredcites →https://doi.org/10.1007/bf00608215openalex-snapshot

Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism

inferredcites →https://doi.org/10.1007/bf01059442openalex-snapshot

Clinical pharmacokinetics of procainamide infusions in relation to acetylator phenotype

inferredcites →https://doi.org/10.1007/bf01086149openalex-snapshot

Pharmacokinetics of isoniazid metabolism in man

inferredcites →https://doi.org/10.1007/bf01418414openalex-snapshot

Coleb-Duriles� bei Angina pectoris: Klinische Erfahrungen

inferredcites →https://doi.org/10.1007/bf01799841openalex-snapshot

A point mutation in an invariant splice donor site leads to exon skipping in two unrelated Dutch patients with dihydropyrimidine dehydrogenase deficiency

inferredcites →https://doi.org/10.1007/bf01857646openalex-snapshot

Minimal effective concentration values of propafenone and 5-hydroxy-propafenone in acute and chronic therapy

inferredcites →https://doi.org/10.1007/bf02220616openalex-snapshot

Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers

inferredcites →https://doi.org/10.1007/bf02220617openalex-snapshot

Steady-state plasma levels of clomipramine and its metabolites: Impact of the sparteine/debrisoquine oxidation polymorphism

inferredcites →https://doi.org/10.1007/bf02245444openalex-snapshot

Regional brain distribution of risperidone and its active metabolite 9-hydroxy-risperidone in the rat

inferredcites →https://doi.org/10.1007/bf02246302openalex-snapshot

A PET study of D2 and 5-HT2 receptor occupancy induced by risperidone in poor metabolizers of debrisoquin and risperidone

inferredcites →https://doi.org/10.1007/bf02246640openalex-snapshot

Steady-state plasma levels of nortriptyline and its 10-hydroxy metabolite: relationship to theCYP2D6 genotype

inferredcites →https://doi.org/10.1007/bf02284955openalex-snapshot

24-hour anti-ischaemic action with once daily nifedipine

inferredcites →https://doi.org/10.1007/bf02333018openalex-snapshot

Lack of effect of mianserin on the symptoms of diabetic neuropathy

inferredcites →https://doi.org/10.1007/bf02455990openalex-snapshot

Studies on the metabolism of perhexiline in man

inferredcites →https://doi.org/10.1007/bf02897232openalex-snapshot

6-Thioguanine nucleotide accumulation in red blood cells during maintenance chemotherapy for childhood acute lymphoblastic leukemia, and its relation to leukopenia

inferredcites →https://doi.org/10.1007/bf03003735openalex-snapshot

Abnormal reaction to procaine and succinylcholine in a patient with inherited atypical plasma cholinesterase: case report

inferredcites →https://doi.org/10.1007/bf03019096openalex-snapshot

Atypical plasma cholinesterase. A personal discovery story: a tale of three cities

inferredcites →https://doi.org/10.1007/bf03019772openalex-snapshot

High epidural block with chloroprocaine in a parturient with low pseudo-cholinesterase activity

inferredcites →https://doi.org/10.1007/bf03258249openalex-snapshot

Relationships Between Debrisoquine Hydroxylation and Propafenone Pharmacokinetics

inferredcites →https://doi.org/10.1007/pl00008711openalex-snapshot

Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency

inferredcites →https://doi.org/10.1007/s00125-003-1034-7openalex-snapshot

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide

inferredcites →https://doi.org/10.1007/s00125-003-1181-xopenalex-snapshot

Gemfibrozil considerably increases the plasma concentrations of rosiglitazone

inferredcites →https://doi.org/10.1007/s00210-003-0815-3openalex-snapshot

Cytochrome P450 3A and their regulation

inferredcites →https://doi.org/10.1007/s00213-002-1059-5openalex-snapshot

Maintenance therapy with zuclopenthixol decanoate: associations between plasma concentrations, neurological side effects and CYP2D6 genotype

inferredcites →https://doi.org/10.1007/s002130050281openalex-snapshot

Non-functional CYP2D6 alleles and risk for neuroleptic-induced movement disorders in schizophrenic patients

inferredcites →https://doi.org/10.1007/s002130051171openalex-snapshot

Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone

inferredcites →https://doi.org/10.1007/s00228-001-0376-7openalex-snapshot

The role of CYP2C9 genotype in the metabolism of diclofenac in vivo and in vitro

inferredcites →https://doi.org/10.1007/s00228-002-0426-9openalex-snapshot

Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis

inferredcites →https://doi.org/10.1007/s00228-002-0445-6openalex-snapshot

The role of CYP2C19 in amitriptyline N-demethylation in Chinese subjects

inferredcites →https://doi.org/10.1007/s00228-002-0509-7openalex-snapshot

Polymorphic oxidative metabolism of proguanil in a Nigerian population

inferredcites →https://doi.org/10.1007/s00228-003-0574-6openalex-snapshot

Differences in flurbiprofen pharmacokinetics between CYP2C9*1/*1, *1/*2, and *1/*3 genotypes

inferredcites →https://doi.org/10.1007/s00228-003-0576-4openalex-snapshot

Thioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype

inferredcites →https://doi.org/10.1007/s00228-003-0580-8openalex-snapshot

Determination of bleeding risk using genetic markers in patients taking phenprocoumon

inferredcites →https://doi.org/10.1007/s00228-003-0588-0openalex-snapshot

CYP2C9 genotypes and diclofenac metabolism in Spanish healthy volunteers.

inferredcites →https://doi.org/10.1007/s00228-003-0595-1openalex-snapshot

Effect of the CYP2D6 genotype on the pharmacokinetics of tropisetron in healthy Korean subjects

inferredcites →https://doi.org/10.1007/s00228-003-0627-xopenalex-snapshot

Effect of ketoconazole on venlafaxine plasma concentrations in extensive and poor metabolisers of debrisoquine

inferredcites →https://doi.org/10.1007/s00228-003-0664-5openalex-snapshot

Effect of the single CYP2C9*3 allele on pharmacokinetics and pharmacodynamics of losartan in healthy Japanese subjects

inferredcites →https://doi.org/10.1007/s00228-003-0701-4openalex-snapshot

Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study

inferredcites →https://doi.org/10.1007/s00228-004-0740-5openalex-snapshot

Identification of cytochromes P 450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro

inferredcites →https://doi.org/10.1007/s00228-004-0753-0openalex-snapshot

Genetic polymorphism of cytochrome P 450 2C9 in diphenylhydantoin-induced cutaneous adverse drug reactions

inferredcites →https://doi.org/10.1007/s00228-004-0767-7openalex-snapshot

Pharmacokinetics of midazolam in CYP3A4- and CYP3A5-genotyped subjects

inferredcites →https://doi.org/10.1007/s00228-004-0853-xopenalex-snapshot

Effect of erythromycin on metabolism of quetiapine in Chinese suffering from schizophrenia

inferredcites →https://doi.org/10.1007/s00228-005-0052-4openalex-snapshot

Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study

inferredcites →https://doi.org/10.1007/s00228-005-0901-1openalex-snapshot

Effect of CYP2C19 and MDR1 polymorphisms on cure rate in patients with acid-related disorders with Helicobacter pylori infection

inferredcites →https://doi.org/10.1007/s002280000246openalex-snapshot

Genotype–phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects

inferredcites →https://doi.org/10.1007/s002280050079openalex-snapshot

Quinidine inhibits the 7-hydroxylation of chlorpromazine in extensive metabolisers of debrisoquine

inferredcites →https://doi.org/10.1007/s002280050113openalex-snapshot

Effect of moderate or severe liver dysfunction on the pharmacokinetics of γ-hydroxybutyric acid

inferredcites →https://doi.org/10.1007/s002280050200openalex-snapshot

Codeine and morphine in extensive and poor metabolizers of sparteine: pharmacokinetics, analgesic effect and side effects

inferredcites →https://doi.org/10.1007/s002280050220openalex-snapshot

Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: a prospective study

inferredcites →https://doi.org/10.1007/s002280050247openalex-snapshot

Different effects of inhibitors on the O - and N -demethylation of codeine in human liver microsomes

inferredcites →https://doi.org/10.1007/s002280050353openalex-snapshot

The effect of codeine on gastrointestinal transit in extensive and poor metabolisers of debrisoquine

inferredcites →https://doi.org/10.1007/s002280050420openalex-snapshot

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin

inferredcites →https://doi.org/10.1007/s002280050495openalex-snapshot

Influence of the cytochrome P4502D6*4 allele on the pharmacokinetics of controlled-release metoprolol

inferredcites →https://doi.org/10.1007/s002280050628openalex-snapshot

The pharmacokinetics of carvedilol and its metabolites after single and multiple dose oral administration in patients with hypertension and renal insufficiency

inferredcites →https://doi.org/10.1007/s002280050689openalex-snapshot

Drug extrapyramidal side effects. CYP2D6 genotypes and phenotypes

inferredcites →https://doi.org/10.1007/s002280050703openalex-snapshot

CYP2C19 polymorphism effect on phenobarbitone

inferredcites →https://doi.org/10.1007/s002280050722openalex-snapshot

Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C9 * 3 allele

inferredcites →https://doi.org/10.1007/s002280050737openalex-snapshot

The impact of the CYP2D6 and CYP2C19 genotypes on venlafaxine pharmacokinetics in a Japanese population

inferredcites →https://doi.org/10.1007/s002280100268openalex-snapshot

Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine

inferredcites →https://doi.org/10.1007/s002280100342openalex-snapshot

Comparison of the kinetic disposition of and serum gastrin change by lansoprazole versus rabeprazole during an 8-day dosing scheme in relation to CYP2C19 polymorphism

inferredcites →https://doi.org/10.1007/s002280100343openalex-snapshot

Olanzapine disposition in humans is unrelated to CYP1A2 and CYP2D6 phenotypes

inferredcites →https://doi.org/10.1007/s002280100372openalex-snapshot

Risperidone metabolism in relation to CYP2D6*10 allele in Korean schizophrenic patients

inferredcites →https://doi.org/10.1007/s002280100373openalex-snapshot

The major fluvoxamine metabolite in urine is formed by CYP2D6

inferredcites →https://doi.org/10.1007/s00280-003-0568-1openalex-snapshot

Intermittent FLDP: 24-h infusion of 5-FU on days 1, 3 and 5 combined with low-dose cisplatin on days 1–5 for gastric cancer, and its pharmacologic and kinetic rationale

inferredcites →https://doi.org/10.1007/s002800050635openalex-snapshot

Inter- and intraindividual variation in dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells

inferredcites →https://doi.org/10.1007/s10038-004-0188-6openalex-snapshot

A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin

inferredcites →https://doi.org/10.1007/s10147-004-0463-8openalex-snapshot

Cancer pharmacogenomics: achievements in basic research

inferredcites →https://doi.org/10.1016/0002-8703(93)90122-popenalex-snapshot

Medical complications of cocaine: Possible relationship to low plasma cholinesterase enzyme

inferredcites →https://doi.org/10.1016/0002-9343(73)90084-3openalex-snapshot

Late toxicity to hydralazine resembling systemic lupus erythematosus or rheumatoid arthritis

inferredcites →https://doi.org/10.1016/0006-2952(88)90068-8openalex-snapshot

Hydrolysis of 3H-bambuterol, a carbamate prodrug of terbutaline, in blood from humans and laboratory animals in vitro

inferredcites →https://doi.org/10.1016/0006-2952(88)90349-8openalex-snapshot

Circadian rhythm of rat liver dihydropyrimidine dehydrogenase

inferredcites →https://doi.org/10.1016/0006-2952(90)90283-qopenalex-snapshot

Inhibitory studies of mexiletine and dextromethorphan oxidation in human liver microsomes

inferredcites →https://doi.org/10.1016/0006-2952(91)90530-iopenalex-snapshot

Interactions of bambuterol with human serum cholinesterase of the genotypes EuEu (normal), EaEa (atypical) and EuEa

inferredcites →https://doi.org/10.1016/0006-2952(95)00021-qopenalex-snapshot

In vitro characterization of cytochrome P450 catalysed metabolism of the antiemetic tropisetron

inferredcites →https://doi.org/10.1016/0009-9236(95)90020-9openalex-snapshot

Pharmacokinetics of losartan, an angiotensin II receptor antagonist, and its active metabolite EXP3174 in humans

inferredcites →https://doi.org/10.1016/0009-9236(95)90036-5openalex-snapshot

Stereoselective disposition of carvedilol is determined by CYP2D6*

inferredcites →https://doi.org/10.1016/0009-9236(95)90049-7openalex-snapshot

Dihydrocodeine: A new opioid substrate for the polymorphic CYP2D6 in humans*

inferredcites →https://doi.org/10.1016/0009-9236(95)90151-5openalex-snapshot

Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population*

inferredcites →https://doi.org/10.1016/0009-9236(95)90171-xopenalex-snapshot

Population characteristics of hepatic dihydropyrimidine dehydrogenase activity, a key metabolic enzyme in 5-fluorouracil chemotherapy*

inferredcites →https://doi.org/10.1016/0009-9236(95)90192-2openalex-snapshot

Comparison of the kinetic disposition and metabolism of E3810, a new proton pump inhibitor, and omeprazole in relation to S-mephenytoin 4′-hydroxylation status

inferredcites →https://doi.org/10.1016/0009-9236(95)90193-0openalex-snapshot

Comparison of the interaction potential of a new proton pump inhibitor, E3810, versus omeprazole with diazepam in extensive and poor metabolizers of S-mephenytoin 4′-hydroxylation*

inferredcites →https://doi.org/10.1016/0009-9236(95)90199-xopenalex-snapshot

Chlorpheniramine plasma concentration and histamine H1-receptor occupancy*

inferredcites →https://doi.org/10.1016/0009-9236(95)90230-9openalex-snapshot

Moclobemide, a substrate of CYP2C19 and an inhibitor of CYP2C19, CYP2D6, and CYP1A2: A panel study*

inferredcites →https://doi.org/10.1016/0009-9236(95)90242-2openalex-snapshot

Propranolol disposition in Chinese subjects of different CYP2D6 genotypes*

inferredcites →https://doi.org/10.1016/0009-9236(95)90244-9openalex-snapshot

Effects of felbamate on the pharmacokinetics of phenobarbital

inferredcites →https://doi.org/10.1016/0014-2999(86)90793-4openalex-snapshot

Phenothiazine drug metabolites: Dopamine D2 receptor, α1-and α2-adrenoceptor binding

inferredcites →https://doi.org/10.1016/0024-3205(74)90221-5openalex-snapshot

A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neurons

inferredcites →https://doi.org/10.1016/0024-3205(77)90448-9openalex-snapshot

Hydrolysis of cocaine in human plasma by cholinesterase

inferredcites →https://doi.org/10.1016/0024-3205(80)90642-6openalex-snapshot

Nortriptyline and antipyrine clearance in relation to debrisoquine hydroxylation in man

inferredcites →https://doi.org/10.1016/0024-3205(92)90226-fopenalex-snapshot

In vitro oxidation of oxicam NSAIDs by a human liver cytochrome P450

inferredcites →https://doi.org/10.1016/0028-3908(92)90100-4openalex-snapshot

Comparison of norfluoxetine enantiomers as serotonin uptake inhibitors in vivo

inferredcites →https://doi.org/10.1016/0035-9203(95)90434-4openalex-snapshot

Japanese poor metabolizers of proguanil do not have an increased risk of malaria chemoprophylaxis breakthrough

inferredcites →https://doi.org/10.1016/0041-008x(86)90398-4openalex-snapshot

Cardiotoxicity of thioridazine and two stereoisomeric forms of thioridazine 5-sulfoxide in the isolated perfused rat heart

inferredcites →https://doi.org/10.1016/0041-3879(73)90013-5openalex-snapshot

A controlled comparison of two fully supervised once-weekly regimens in the treatment of newly diagnosed pulmonary tuberculosis

inferredcites →https://doi.org/10.1016/0041-3879(86)90003-6openalex-snapshot

Hepatic toxicity in south indian patients during treatment of tuberculosis with short-course regimens containing isoniazid, rifampicin and pyrazinamide

inferredcites →https://doi.org/10.1016/0091-6749(84)90117-9openalex-snapshot

Autoallergic reactions induced by procainamide

inferredcites →https://doi.org/10.1016/0140-6736(90)91745-vopenalex-snapshot

Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia

inferredcites →https://doi.org/10.1016/0140-6736(93)92546-6openalex-snapshot

Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine

inferredcites →https://doi.org/10.1016/0140-6736(93)92547-7openalex-snapshot

Storage of skin grafts in honey

inferredcites →https://doi.org/10.1016/0163-7258(90)90080-lopenalex-snapshot

Metabolism of pyrimidine analogues and their nucleosides

inferredcites →https://doi.org/10.1016/0167-5273(86)90146-4openalex-snapshot

Perhexiline maleate treatment for severe angina pectoris — correlations with pharmacokinetics

inferredcites →https://doi.org/10.1016/0959-8049(94)00216-ropenalex-snapshot

A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil

inferredcites →https://doi.org/10.1016/j.bbrc.2003.08.103openalex-snapshot

In vitro characterization of four novel non-functional variants of the thiopurine S-methyltransferase

inferredcites →https://doi.org/10.1016/j.bbrc.2004.05.116openalex-snapshot

Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens

inferredcites →https://doi.org/10.1016/j.braindev.2004.02.010openalex-snapshot

A major influence of CYP2C19 genotype on the steady-state concentration of N-desmethylclobazam

inferredcites →https://doi.org/10.1016/j.cca.2005.07.013openalex-snapshot

Effect of the CYP2C9*3 allele on lornoxicam metabolism

inferredcites →https://doi.org/10.1016/j.clpt.2003.08.001openalex-snapshot

Altered pharmacokinetics and excessive hypotensive effect of candesartan in a patient with the CYP2C9*1/*3 genotype

inferredcites →https://doi.org/10.1016/j.clpt.2003.09.015openalex-snapshot

CYP2C9 genotypes and dose requirements during the induction phase of oral anticoagulant therapy

inferredcites →https://doi.org/10.1016/j.clpt.2003.10.001openalex-snapshot

Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin

inferredcites →https://doi.org/10.1016/j.clpt.2003.10.004openalex-snapshot

CYP2D6genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects

inferredcites →https://doi.org/10.1016/j.clpt.2003.11.344openalex-snapshot

Disposition of chlorpromazine in Korean healthy subjects with CYP2D6 wild type and *10B mutation

inferredcites →https://doi.org/10.1016/j.clpt.2003.12.001openalex-snapshot

Methylated metabolites of 6-mercaptopurine are associated with hepatotoxicity*1

inferredcites →https://doi.org/10.1016/j.clpt.2003.12.015openalex-snapshot

Cyp2d6 genotype: impact on adverse effects and nonresponse during treatment with antidepressants—a pilot study

inferredcites →https://doi.org/10.1016/j.clpt.2003.12.017openalex-snapshot

Acenocoumarol stabilization is delayed in CYP2C9*3 carriers

inferredcites →https://doi.org/10.1016/j.clpt.2004.01.008openalex-snapshot

Pharmacogenetics of acenocoumarol pharmacodynamics

inferredcites →https://doi.org/10.1016/j.clpt.2004.01.009openalex-snapshot

CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation

inferredcites →https://doi.org/10.1016/j.clpt.2004.01.010openalex-snapshot

UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer*1

inferredcites →https://doi.org/10.1016/j.clpt.2004.02.002openalex-snapshot

Pharmacokinetics of voriconazole and cytochrome p450 2C19 genetic status

inferredcites →https://doi.org/10.1016/j.clpt.2004.02.005openalex-snapshot

CYP3A5 genotype and midazolam clearance in Australian patients receiving chemotherapy*1

inferredcites →https://doi.org/10.1016/j.clpt.2004.03.002openalex-snapshot

CYP2C9 genotypes and the pharmacokinetics of tenoxicam in Brazilians*1

inferredcites →https://doi.org/10.1016/j.clpt.2004.03.009openalex-snapshot

Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states*1

inferredcites →https://doi.org/10.1016/j.clpt.2004.04.006openalex-snapshot

Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms*1

inferredcites →https://doi.org/10.1016/j.clpt.2004.05.002openalex-snapshot

CYP2C19 polymorphism is a major predictor of treatment failure in white patients by use of lansoprazole-based quadruple therapy for eradication of

inferredcites →https://doi.org/10.1016/j.clpt.2004.07.002openalex-snapshot

Impact of the ultrarapid metabolizer genotype of cytochrome P450 2D6 on metoprolol pharmacokinetics and pharmacodynamics

inferredcites →https://doi.org/10.1016/j.clpt.2004.08.006openalex-snapshot

Effects of cytochrome P450 2C9 polymorphisms on phenprocoumon anticoagulation status

inferredcites →https://doi.org/10.1016/j.clpt.2004.08.009openalex-snapshot

Clinical consequences of cytochrome P450 2C9 polymorphisms

inferredcites →https://doi.org/10.1016/j.clpt.2004.08.020openalex-snapshot

Pharmacokinetics and genotypes do not predict metoprolol adverse events or efficacy in hypertension

inferredcites →https://doi.org/10.1016/j.clpt.2004.08.024openalex-snapshot

polymorphisms and the interindividual variability in pharmacokinetics and pharmacodynamics of the loop diuretic drug torsemide

inferredcites →https://doi.org/10.1016/j.clpt.2004.10.006openalex-snapshot

β-adrenergic Receptor Polymorphisms and Responses during Titration of Metoprolol Controlled Release/extended Release in Heart Failure*

inferredcites →https://doi.org/10.1016/j.clpt.2004.12.029openalex-snapshot

Effect of CYP2C8 genotype on rosiglitazone pharmacokinetics

inferredcites →https://doi.org/10.1016/j.clpt.2004.12.266openalex-snapshot

Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics of pioglitazone

inferredcites →https://doi.org/10.1016/j.clpt.2005.01.018openalex-snapshot

Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

inferredcites →https://doi.org/10.1016/j.clpt.2005.02.010openalex-snapshot

Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation

inferredcites →https://doi.org/10.1016/j.clpt.2005.03.008openalex-snapshot

Pharmacokinetics of glimepiride and cytochrome P450 2C9 genetic polymorphisms

inferredcites →https://doi.org/10.1016/j.clpt.2005.06.005openalex-snapshot

Cytochrome P450 2C9 genotype: Impact on celecoxib safety and pharmacokinetics in a pediatric patient

inferredcites →https://doi.org/10.1016/j.clpt.2005.06.006openalex-snapshot

, but not , polymorphisms affect the pharmacokinetics and pharmacodynamics of glyburide in Chinese subjects

inferredcites →https://doi.org/10.1016/j.clpt.2005.06.014openalex-snapshot

Influence of genotypes on the pharmacokinetics and pharmacodynamics of piroxicam

inferredcites →https://doi.org/10.1016/j.clpt.2005.07.004openalex-snapshot

Impact of genotype on adverse effects during treatment with metoprolol: A prospective clinical study

inferredcites →https://doi.org/10.1016/j.clpt.2005.08.017openalex-snapshot

Esomeprazole-induced healing of gastroesophageal reflux disease is unrelated to the genotype of CYP2C19: Evidence from clinical and pharmacokinetic data

inferredcites →https://doi.org/10.1016/j.clpt.2005.08.020openalex-snapshot

CYP2C19 genotype affects diazepam pharmacokinetics and emergence from general anesthesia

inferredcites →https://doi.org/10.1016/j.clpt.2005.09.005openalex-snapshot

Evidence for morphine-independent central nervous opioid effects after administration of codeine: Contribution of other codeine metabolites

inferredcites →https://doi.org/10.1016/j.clpt.2005.10.002openalex-snapshot

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants

inferredcites →https://doi.org/10.1016/j.clpt.2005.11.007openalex-snapshot

Accumulation of celecoxib with a 7-fold higher drug exposure in individuals homozygous for CYP2C9*3

inferredcites →https://doi.org/10.1016/j.clpt.2005.11.011openalex-snapshot

Influence of coagulation factor, vitamin K epoxide reductase complex subunit 1, and cytochrome P450 2C9 gene polymorphisms on warfarin dose requirements

inferredcites →https://doi.org/10.1016/j.lfs.2003.07.018openalex-snapshot

CYP2C polymorphisms, phenytoin metabolism and gingival overgrowth in epileptic subjects

inferredcites →https://doi.org/10.1016/s0002-9270(02)04194-1openalex-snapshot

N -Acetyltransferase 1 and 2 Genotypes Do Not Predict Response Or Toxicity To Treatment With Mesalamine and Sulfasalazine in Patients With Ulcerative Colitis

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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Computational Exploration of Small Molecules as Inhibitor Targeting Cytochrome P4502d6

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Xenobiotic Metabolism

inferred← citeshttps://doi.org/10.1002/9780470571224.pse058openalex-snapshot

Linkage Between Toxicology of Drugs and Metabolism

inferred← citeshttps://doi.org/10.1002/9780470689332.furreadopenalex-snapshot