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Characteristics and Significance of the Amorphous State in Pharmaceutical Systems

https://doi.org/10.1021/js9601896
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Outgoing claims: the papers this work cites, builds on, or argues with.

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The glass transition concentration
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Ideal copolymers and the second‐order transitions of synthetic rubbers. i. non‐crystalline copolymers
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Dissolution Rates of High Energy Sulfathiazole‐Povidone Coprecipitates II: Characterization of Form of Drug Controlling Its Dissolution Rate via Solubility Studies
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Quantitative Crystallinity Determinations for β-Lactam Antibiotics by Solution Calorimetry: Correlations with Stability
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Cefoxitin Sodium: Solution and Solid-State Chemical Stability Studies
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Effects of Heat Treatment on the Permeability of Polyvinyl Alcohol Films to a Hydrophilic Solute
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Glass–Rubber Transitions of Cellulosic Polymers by Dynamic Mechanical Analysis
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Chemical Stability of Indomethacin in the Solid Amorphous and Molten States
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Crystallization of Indomethacin from the Amorphous State below and above Its Glass Transition Temperature
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Inhibition of indomethacin crystallization in poly(vinylpyrrolidone) coprecipitates
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Raman spectroscopic method for determining the crystallinity of polyethylene
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Crystallization in polymers
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On the Relationship between Specific Volume and Crystallinity of Starch
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Peptide and Protein Drugs
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Raman and differential thermal analysis studies of aqueous CsF solution in the glassy state
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A Raman spectroscopic study of the morphological structure of the polyethylenes
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Heat capacity measurement by modulated DSC at constant temperature
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Molecular motion in glassy water-malto-oligosaccharide (maltodextrin) mixtures as studied by conventional and saturation-transfer spin-probe e.s.r. spectroscopy
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The mechanism of cryoprotection of proteins by solutes
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Classification of non-crystalline solids
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Heat capacities and glass transitions of ground amorphous solid and liquid-quenched glass of tri-O-methyl-ß-cyclodextrin
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Viscosity of chalcogenide glass-forming liquids: an anomaly in the ‘strong’ and ‘fragile’ classification
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Volumetric properties of polystyrene: influence of temperature, molecular weight and thermal treatment
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Glass transition behaviour of compatible polymer blends
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Gas transport properties in polycarbonate films with various unrelaxed volumes
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Cooperative relaxations in amorphous polymers studied by thermally stimulated current depolarization
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Discovery of crystal nucleation proceeding much below the glass transition temperature in a supercooled liquid
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Pharmaceutical applications of dynamic mechanical thermal analysis
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Thermal analysis of glassy pharmaceuticals
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Thermal analysis and calorimetric methods in the characterisation of polymorphs and solvates
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Calorimetric investigation on glassy crystals
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Effect of chemical structure of amorphous polymers on heat capacity difference at glass transition temperature
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Characterisation of amorphous materials by modulated differential scanning calorimetry
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Liquid fragility and the glass transition in water and aqueous solutions
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Peptide and protein drug delivery
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Peptide and protein drug delivery
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Effect of physical changes on the rates of nonenzymic browning and related reactions
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Viscoelastic Properties of Polymers
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Evaluation of heat-conduction microcalorimetry in pharmaceutical stability studies. VI. Continuous monitoring of the interaction of water vapour with powders and powder mixtures at various relative humidities
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True density and thermal expansivity of pharmaceutical solids: comparison of methods and assessment of crystallinity
inferredcites →https://doi.org/10.1016/0378-5173(90)90221-oopenalex-snapshot
The molecular basis of moisture effects on the physical and chemical stability of drugs in the solid state
inferredcites →https://doi.org/10.1016/0378-5173(92)90221-mopenalex-snapshot
Investigation of felodipine polymorphism and its glassy state
inferredcites →https://doi.org/10.1016/0378-5173(94)90089-2openalex-snapshot
An automated controlled atmosphere microbalance for the measurement of moisture sorption
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The effect of pre-compaction processing and storage conditions on powder and compaction properties of some crystalline materials
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Assessment of disorder in crystalline solids
inferredcites →https://doi.org/10.1016/0378-5173(95)00008-7openalex-snapshot
Quantification of crystallinity in blends of lyophilized and crystalline MK-0591 using x-ray powder diffraction
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The influence of additives on the recrystallisation of amorphous spray dried lactose
inferredcites →https://doi.org/10.1016/0378-5173(95)04463-9openalex-snapshot
Modulated temperature differential scanning calorimetry: A novel approach to pharmaceutical thermal analysis
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Glass Formation and Glassy Behavior
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Crystallization of Polymers
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Interactions of Stabilizers with Proteins During Freezing and Drying
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Phosphorescence Probes of the Glassy State in Amorphous Sucrose
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Vitrified dilute aqueous solutions. 4. Effects of electrolytes and polyhydric alcohols on the glass transition features of hyperquenched aqueous solutions
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Molecular motion in sucrose-water mixtures in the liquid and glassy state as studied by spin probe ESR
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Glass transition temperatures for simple molecular liquids and their binary solutions
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Pressure dependence of the glass transition temperature in ionic liquids and solutions. Evidence against free volume theories
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Dependence of the glass transition temperature on heating and cooling rate
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Volumetric interpretation of viscosity for concentrated and dilute sugar solutions
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A kinetic and x-ray diffraction study of the solid state rearrangement of methyl p-dimethylaminobenzenesulfonate. Reaction rate enhancement due to proper orientation in a crystal
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Enhancement of a chemical reaction rate by proper orientation of reacting molecules in the solid state
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The Temperature Dependence of Relaxation Mechanisms in Amorphous Polymers and Other Glass-forming Liquids
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Heat capacities of liquids. Estimation of heat capacity at constant pressure and 25.deg., using additivity rules
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Supercooled Liquids and Glasses
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Effects of Solid-State Processing on Water Vapor Sorption by Aspirin
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Sorption in glassy polymers
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Glass Transition of Amorphous Polymer Surfaces
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Solvent Self-Diffusion in Rubbery Polymer-Solvent Systems
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Solvent Self-Diffusion in Glassy Polymer-Solvent Systems
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Glass Transition Temperatures of Polymers from Molecular Dynamics Simulations
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Analysis of the glass transition temperature of miscible polymer blends
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Small-angle x-ray scattering study of density fluctuation in polystyrene annealed below the glass transition temperature
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The Relationship Between the Glass Transition Temperature and Water Vapor Absorption by Poly(vinylpyrrolidone)
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Preformulation Studies Involving Moisture Uptake in Solid Dosage Forms
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Influence of Physical Aging on Mechanical Properties of Polymer Free Films: The Prediction of Long-Term Aging Effects on the Water Permeability and Dissolution Rate of Polymer Film-Coated Tablets
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Process-Induced Crystallinity Changes in Albuterol Sulfate and Its Effect on Powder Physical Stability
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The Effect of Moisture on the Mechanical and Powder Flow Properties of Microcrystalline Cellulose
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Electrolyte-Induced Changes in Glass Transition Temperatures of Freeze-Concentrated Solutes
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Molecular Mobility of Amorphous Pharmaceutical Solids Below Their Glass Transition Temperatures
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The Use of Solution Theories for Predicting Water Vapor Absorption by Amorphous Pharmaceutical Solids: A Test of the Flory–Huggins and Vrentas Models
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The Relationship Between the Glass Transition Temperature and the Water Content of Amorphous Pharmaceutical Solids
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Non-Isothermal and Isothermal Crystallization of Sucrose from the Amorphous State
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Effect of Moisture Sorption on Tabletting Characteristics of Spray Dried (15% Amorphous) Lactose
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Molecular Mobility in Mixtures of Absorbed Water and Solid Poly(vinylpyrrolidone)
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Thermomechanical properties of small-carbohydrate–water glasses and ‘rubbers’. Kinetically metastable systems at sub-zero temperatures
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Interface and surface effects on the glass-transition temperature in thin polymer films
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On the Relative Roles of Free Volume and Activation Energy in the Viscosity of Liquids
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Molecular Transport in Liquids and Glasses
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The Viscosity of Undercooled Liquid Glucose
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Rate of Nucleation in Condensed Systems
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Direct measurement of free-energy barrier to nucleation of crystallites in amorphous silicon thin films
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Slow processes in viscous liquids: Stress and structural relaxation, chemical reaction freezing, crystal nucleation and microemulsion arrest, in relation to liquid fragility
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Breakdown of the Stokes–Einstein relation in supercooled liquids
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The old problems of glass and the glass transition, and the many new twists.
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Amorphism and Physicochemical Stability of Spray-dried Frusemide
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Visual Observations of the Amorphous-Amorphous Transition in H 2 O Under Pressure
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Formation of Glasses from Liquids and Biopolymers
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A Topographic View of Supercooled Liquids and Glass Formation
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The Microscopic Basis of the Glass Transition in Polymers from Neutron Scattering Studies
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Physical Aging in Polymer Glasses
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Viscoelastic Properties of Polymers
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Glassy state of pharmaceuticals. III. Thermal properties and stability of glassy pharmaceuticals and their binary glass systems.
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Glassy state of pharmaceuticals. IV. Studies on glassy pharmaceuticals by thermomechanical analysis.
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Equilibrium Moisture Content of Pharmaceutical Excipients
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Mechanism of Hardness of Aged Compacts
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Thermal Analysis Studies of Glass Dispersion Systems
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Applications of low frequency dielectric spectroscopy to the pharmaceutical sciences

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Physical Characteristics and Chemical Degradation of Amorphous Quinapril Hydrochloride
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Relationship between the crystallization rates of amorphous nifedipine, phenobarbital, and flopropione, and their molecular mobility as measured by their enthalpy relaxation and 1 H NMR relaxation times
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Polymorphs, Solvates and Hydrates
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Physical Aging of Polymers
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The Relationship Between “BET” and “Free Volume”‐Derived Parameters for Water Vapor Absorption into Amorphous Solids
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Application of Diffuse Reflectance Near‐Infrared Spectroscopy for Determination of Crystallinity
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Crystallization Inhibition in Solid Dispersions of MK‐0591 and Poly(vinylpyrrolidone) Polymers
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Proteinkristalle als neue Katalysatoren
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Vibrational Spectroscopy of Solid‐State Forms – Introduction, Principles and Overview
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Plant Desiccation Tolerance
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The Glassy State in Dry Seeds and Pollen
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The Value of Portable Spectrometers for the Analysis of Counterfeit Pharmaceuticals
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inferred← citeshttps://doi.org/10.1002/9783527652693.ch13openalex-snapshot
Study of Disordered Materials by Terahertz Spectroscopy
inferred← citeshttps://doi.org/10.1002/9783527652693.ch2openalex-snapshot
Influence of Disorder on Dissolution
inferred← citeshttps://doi.org/10.1002/9783527675272.ch05openalex-snapshot
Formulation, Drug Product, and Delivery: Considerations for Fc‐Fusion Proteins
inferred← citeshttps://doi.org/10.1002/9783527802104.ch13openalex-snapshot
The Roles of Acid–Base Relationships, Interfaces, and Molecular Mobility in Stabilization During Drying and in the Solid State
inferred← citeshttps://doi.org/10.1002/9783527812172.ch9openalex-snapshot
Physical Characterization Techniques to Access Amorphous Nature
inferred← citeshttps://doi.org/10.1002/adma.201802120openalex-snapshot
Recent Advances in Metallic Glass Nanostructures: Synthesis Strategies and Electrocatalytic Applications
inferred← citeshttps://doi.org/10.1002/aic.11370openalex-snapshot
An analytical model for internal moisture content during the decreasing drying rate period
inferred← citeshttps://doi.org/10.1002/aic.14979openalex-snapshot
Drop printing of pharmaceuticals: Effect of molecular weight on PEG coated‐naproxen/PEG 3350 solid dispersions
inferred← citeshttps://doi.org/10.1002/aic.15615openalex-snapshot
Dissolution of semicrystalline polymer fibers: Numerical modeling and parametric analysis
inferred← citeshttps://doi.org/10.1002/aic.690480602openalex-snapshot
Engineering pharmaceutical stability with amorphous solids
inferred← citeshttps://doi.org/10.1002/ange.201501032openalex-snapshot
Extensively Reversible Thermal Transformations of a Bistable, Fluorescence‐Switchable Molecular Solid: Entry into Functional Molecular Phase‐Change Materials
inferred← citeshttps://doi.org/10.1002/anie.201501032openalex-snapshot
Extensively Reversible Thermal Transformations of a Bistable, Fluorescence‐Switchable Molecular Solid: Entry into Functional Molecular Phase‐Change Materials
inferred← citeshttps://doi.org/10.1002/app.27828openalex-snapshot
Evaluation of solubility parameters for nonvolatile branched hydrocarbons by inverse gas chromatography
inferred← citeshttps://doi.org/10.1002/bit.1069openalex-snapshot
Stability of crystalline proteins
inferred← citeshttps://doi.org/10.1002/bit.22832openalex-snapshot
Crystallization of recombinant human growth hormone at elevated pressures: Pressure effects on PEG‐induced volume exclusion interactions
inferred← citeshttps://doi.org/10.1002/ceat.201300355openalex-snapshot
Concentrated Fenofibrate Nanoparticle Suspensions from Melt Emulsification for Enhanced Drug Dissolution
inferred← citeshttps://doi.org/10.1002/ceat.201400120openalex-snapshot
Effect of Co‐Grinding on Crystallinity of Clopidogrel Bisulfate
inferred← citeshttps://doi.org/10.1002/chin.199713319openalex-snapshot
ChemInform Abstract: Characteristics and Significance of the Amorphous State in Pharmaceutical Systems
inferred← citeshttps://doi.org/10.1002/ddr.10365openalex-snapshot
Solubility studies on valdecoxib in the presence of carriers, cosolvents, and surfactants
inferred← citeshttps://doi.org/10.1002/ddr.10412openalex-snapshot
Enhancement of dissolution rate of rofecoxib using solid dispersions with urea
inferred← citeshttps://doi.org/10.1002/ejic.200801205openalex-snapshot
Solid‐State NMR Investigation of Ligand Mobility and Reactivity in Transition Metal Complexes
inferred← citeshttps://doi.org/10.1002/jps.10014openalex-snapshot
The Solid‐State Stability of Amorphous Quinapril in the Presence of β‐Cyclodextrins
inferred← citeshttps://doi.org/10.1002/jps.10018openalex-snapshot
Characterization of the thermal properties of microcrystalline cellulose by modulated temperature differential scanning calorimetry
inferred← citeshttps://doi.org/10.1002/jps.10059openalex-snapshot
Protein spray freeze drying. 2. Effect of formulation variables on particle size and stability
inferred← citeshttps://doi.org/10.1002/jps.10068openalex-snapshot
Water Diffusion in Hydrated Crystalline and Amorphous Sugars Monitored Using H/D Exchange
inferred← citeshttps://doi.org/10.1002/jps.10115openalex-snapshot
Effects of mechanical processing on phase composition
inferred← citeshttps://doi.org/10.1002/jps.10146openalex-snapshot
Molecular mobility study of amorphous and crystalline phases of a pharmaceutical product by thermally stimulated current spectrometry
inferred← citeshttps://doi.org/10.1002/jps.10169openalex-snapshot
Physical Stability of Amorphous Pharmaceuticals: Importance of Configurational Thermodynamic Quantities and Molecular Mobility
inferred← citeshttps://doi.org/10.1002/jps.10185openalex-snapshot
Ultrasound‐Compacted Indomethacin/Polyvinylpyrrolidone Systems: Effect of Compaction Process on Particle Morphology and Dissolution Behavior
inferred← citeshttps://doi.org/10.1002/jps.10205openalex-snapshot
Water Vapor Absorption into Amorphous Hydrophobic Drug/Poly(vinylpyrrolidone) Dispersions
inferred← citeshttps://doi.org/10.1002/jps.1033openalex-snapshot
Explanation of the Crystallization Rate of Amorphous Nifedipine and Phenobarbital from Their Molecular Mobility as Measured by 13C Nuclear Magnetic Resonance Relaxation Time and the Relaxation Time Obtained from the Heating Rate Dependence of the Glass Transition Temperature
inferred← citeshttps://doi.org/10.1002/jps.10366openalex-snapshot
General pharmaceutics—The new physical pharmacy
inferred← citeshttps://doi.org/10.1002/jps.1040openalex-snapshot
Annealing to optimize the primary drying rate, reduce freezing‐induced drying rate heterogeneity, and determine T'g in pharmaceutical lyophilization
inferred← citeshttps://doi.org/10.1002/jps.1041openalex-snapshot
Fourier transform Raman spectroscopic study of the interaction of water vapor with amorphous polymers
inferred← citeshttps://doi.org/10.1002/jps.10425openalex-snapshot
Crystallization Kinetics of Amorphous Nifedipine Studied by Model-Fitting and Model-Free Approaches
inferred← citeshttps://doi.org/10.1002/jps.10489openalex-snapshot
Physics of amorphous solids
inferred← citeshttps://doi.org/10.1002/jps.10520openalex-snapshot
Dielectric study of the molecular mobility and the isothermal crystallization kinetics of an amorphous pharmaceutical drug substance
inferred← citeshttps://doi.org/10.1002/jps.10526openalex-snapshot
Molecular mobility‐based estimation of the crystallization rates of amorphous nifedipine and phenobarbital in poly(vinylpyrrolidone) solid dispersions
inferred← citeshttps://doi.org/10.1002/jps.10535openalex-snapshot
Partial Characterization of Different Mixtures of Solids by Measuring the Optical Nonlinear Response
inferred← citeshttps://doi.org/10.1002/jps.10582openalex-snapshot
Evaluation of glassy-state dynamics from the width of the glass transition: Results from theoretical simulation of differential scanning calorimetry and comparisons with experiment
inferred← citeshttps://doi.org/10.1002/jps.10587openalex-snapshot
Optimizing Storage Stability of Lyophilized Recombinant Human Interleukin-11 with Disaccharide/Hydroxyethyl Starch Mixtures
inferred← citeshttps://doi.org/10.1002/jps.20061openalex-snapshot
Estimation of the fragility index of indomethacin by DSC using the heating and cooling rate dependency of the glass transition
inferred← citeshttps://doi.org/10.1002/jps.20138openalex-snapshot
The Stability of lyophilized lipid/DNA complexes during prolonged storage
inferred← citeshttps://doi.org/10.1002/jps.20177openalex-snapshot
Immobilization of Nonviral Vectors During the Freezing Step of Lyophilization
inferred← citeshttps://doi.org/10.1002/jps.20282openalex-snapshot
Physicochemical Characterization of Ricobendazole: I. Solubility, Lipophilicity, and Ionization Characteristics
inferred← citeshttps://doi.org/10.1002/jps.20298openalex-snapshot
Calorimetric Investigation of the Structural Relaxation of Amorphous Materials: Evaluating Validity of the Methodologies
inferred← citeshttps://doi.org/10.1002/jps.20333openalex-snapshot
Thermodynamic and dynamic factors involved in the stability of native protein structure in amorphous solids in relation to levels of hydration
inferred← citeshttps://doi.org/10.1002/jps.20424openalex-snapshot
The Influence of Thermal and Mechanical Preparative Techniques on the Amorphous State of Four Poorly Soluble Compounds
inferred← citeshttps://doi.org/10.1002/jps.20455openalex-snapshot
Dielectric Studies of Molecular Motions in Amorphous Solid and Ultraviscous Acetaminophen
inferred← citeshttps://doi.org/10.1002/jps.20458openalex-snapshot
Crystallization of sucrose glass under ambient conditions: Evaluation of crystallization rate and unusual melting behavior of resultant crystals
inferred← citeshttps://doi.org/10.1002/jps.20474openalex-snapshot
Formation and characterization of porous indomethacin-PVP coprecipitates prepared using solvent-free supercritical fluid processing
inferred← citeshttps://doi.org/10.1002/jps.20499openalex-snapshot
Investigating the hydrate conversion propensity of different etoricoxib lots
inferred← citeshttps://doi.org/10.1002/jps.20523openalex-snapshot
Quantitative determination of amorphous cyclosporine in crystalline cyclosporine samples by Fourier transform infrared spectroscopy
inferred← citeshttps://doi.org/10.1002/jps.20532openalex-snapshot
Physical stability of crystal hydrates and their anhydrates in the presence of excipients
inferred← citeshttps://doi.org/10.1002/jps.20575openalex-snapshot
Towards characterization and identification of solid state pharmaceutical mixtures through second harmonic generation
inferred← citeshttps://doi.org/10.1002/jps.20601openalex-snapshot
Dynamic Heat Capacity and Relaxation Time of Ultraviscous Melt and Glassy Acetaminophen
inferred← citeshttps://doi.org/10.1002/jps.20620openalex-snapshot
Impact of Freeze-Drying on Ionization of Sulfonephthalein Probe Molecules in Trehalose–Citrate Systems
inferred← citeshttps://doi.org/10.1002/jps.20633openalex-snapshot
A Calorimetric Investigation of Thermodynamic andMolecular Mobility Contributions to the Physical Stability of Two Pharmaceutical Glasses
inferred← citeshttps://doi.org/10.1002/jps.20644openalex-snapshot
Analytical techniques for quantification of amorphous/crystalline phases in pharmaceutical solids
inferred← citeshttps://doi.org/10.1002/jps.20672openalex-snapshot
Towards an Understanding of the Structurally Based Potential for Mechanically Activated Disordering of Small Molecule Organic Crystals
inferred← citeshttps://doi.org/10.1002/jps.20842openalex-snapshot
The Challenge of Drying Method Selection for Protein Pharmaceuticals: Product Quality Implications
inferred← citeshttps://doi.org/10.1002/jps.20861openalex-snapshot
Dextran or Hydroxyethyl Starch in Sprayfreeze-Dried Trehalose/Mannitol Microparticles Intended as Ballistic Particulate Carriers for Proteins
inferred← citeshttps://doi.org/10.1002/jps.20908openalex-snapshot
Relaxation and Crystallization of Amorphous Carbamazepine Studied by Terahertz Pulsed Spectroscopy
inferred← citeshttps://doi.org/10.1002/jps.20916openalex-snapshot
Physical Characterization of Component Particles Included in Dry Powder Inhalers. I. Strategy Review and Static Characteristics
inferred← citeshttps://doi.org/10.1002/jps.20919openalex-snapshot
Hydrates and Solid-State Reactivity: A Survey of β-Lactam Antibiotics
inferred← citeshttps://doi.org/10.1002/jps.20921openalex-snapshot
Dielectric Relaxation and Crystallization of Ultraviscous Melt and Glassy States of Aspirin, Ibuprofen, Progesterone, and Quinidine
inferred← citeshttps://doi.org/10.1002/jps.20944openalex-snapshot
Assessment of Defects and Amorphous Structure Produced in Raffinose Pentahydrate upon Dehydration
inferred← citeshttps://doi.org/10.1002/jps.20991openalex-snapshot
Characterization of Amorphous Solids with Weak Glass Transitions Using High Ramp Rate Differential Scanning Calorimetry
inferred← citeshttps://doi.org/10.1002/jps.21072openalex-snapshot
Drug–polymer interaction and its significance on the physical stability of nifedipine amorphous dispersion in microparticles of an ammonio methacrylate copolymer and ethylcellulose binary blend
inferred← citeshttps://doi.org/10.1002/jps.21081openalex-snapshot
Correlation between Chemical Reactivity and the Hammett Acidity Function in Amorphous Solids Using Inversion of Sucrose as a Model Reaction
inferred← citeshttps://doi.org/10.1002/jps.21138openalex-snapshot
Role of Thermodynamic, Molecular, and Kinetic Factors in Crystallization from the Amorphous State
inferred← citeshttps://doi.org/10.1002/jps.21174openalex-snapshot
Stabilization of Low Glass Transition Temperature Indomethacin Formulations: Impact of Polymer-Type and Its Concentration
inferred← citeshttps://doi.org/10.1002/jps.21202openalex-snapshot
True Density Analysis of a Freeze-Dried Amorphous Sugar Matrix
inferred← citeshttps://doi.org/10.1002/jps.21212openalex-snapshot
Engineering of Pharmaceutical Materials: An Industrial Perspective
inferred← citeshttps://doi.org/10.1002/jps.21223openalex-snapshot
Physicochemical, Crystallographic, Thermal, and Spectroscopic Behavior of Crystalline and X-ray Amorphous Ciclesonide
inferred← citeshttps://doi.org/10.1002/jps.21252openalex-snapshot
Calorimetric Relaxation and the Glass–Liquid Temperature Range of Acetaminophen–Nifedipine Alloys
inferred← citeshttps://doi.org/10.1002/jps.21255openalex-snapshot
Investigation of the Impact of Annealing on Global Molecular Mobility in Glasses: Optimization for Stabilization of Amorphous Pharmaceuticals
inferred← citeshttps://doi.org/10.1002/jps.21256openalex-snapshot
Polymorph Transitions of Bicalutamide: A Remarkable Example of Mechanical Activation
inferred← citeshttps://doi.org/10.1002/jps.21257openalex-snapshot
Application of a Two-State Kinetic Model to The Heterogeneous Kinetics of Reaction between Cysteine and Hydrogen Peroxide in Amorphous Lyophiles
inferred← citeshttps://doi.org/10.1002/jps.21399openalex-snapshot
Solubility Enhancement of a Poorly Water-Soluble Anti-Malarial Drug: Experimental Design and Use of a Modified Multifluid Nozzle Pilot Spray Drier
inferred← citeshttps://doi.org/10.1002/jps.21429openalex-snapshot
Characterization of Moisture‐Protective Polymer Coatings Using Differential Scanning Calorimetry and Dynamic Vapor Sorption
inferred← citeshttps://doi.org/10.1002/jps.21552openalex-snapshot
Materials Science Tetrahedron—A Useful Tool for Pharmaceutical Research and Development
inferred← citeshttps://doi.org/10.1002/jps.21573openalex-snapshot
Determination of the structural relaxation at the surface of amorphous solid dispersion using inverse gas chromatography
inferred← citeshttps://doi.org/10.1002/jps.21586openalex-snapshot
Freeze-Dry Microscopy of Protein/Sugar Mixtures: Drying Behavior, Interpretation of Collapse Temperatures and a Comparison to Corresponding Glass Transition Data
inferred← citeshttps://doi.org/10.1002/jps.21622openalex-snapshot
Impact of sucrose level on storage stability of proteins in freeze-dried solids: II. Correlation of aggregation rate with protein structure and molecular mobility**This work is a product of the U.S. Government and is not subject to copyright in the United States.
inferred← citeshttps://doi.org/10.1002/jps.21638openalex-snapshot
Ordered Mesoporous Silica Material SBA-15: A Broad-Spectrum Formulation Platform for Poorly Soluble Drugs
inferred← citeshttps://doi.org/10.1002/jps.21647openalex-snapshot
Informatic Calibration of a Materials Properties Database for Predictive Assessment of Mechanically Activated Disordering Potential for Small Molecule Organic Solids
inferred← citeshttps://doi.org/10.1002/jps.21728openalex-snapshot
Local Mobility in Amorphous Pharmaceuticals—Characterization and Implications on Stability
inferred← citeshttps://doi.org/10.1002/jps.21734openalex-snapshot
Differences in the interaction between aryl propionic acid derivatives and poly(vinylpyrrolidone) K30: A multi-methodological approach
inferred← citeshttps://doi.org/10.1002/jps.21799openalex-snapshot
Dielectric Relaxation Study on Tramadol Monohydrate and Its Hydrochloride Salt
inferred← citeshttps://doi.org/10.1002/jps.21816openalex-snapshot
Current status of amorphous formulation and other special dosage forms as formulations for early clinical phases
inferred← citeshttps://doi.org/10.1002/jps.21825openalex-snapshot
Mechanisms of protein stabilization in the solid state
inferred← citeshttps://doi.org/10.1002/jps.21925openalex-snapshot
Solid-State Characterization of Amorphous and Mesomorphous Calcium Ketoprofen
inferred← citeshttps://doi.org/10.1002/jps.21936openalex-snapshot
Solid-State Stability of Spray-Dried Insulin Powder for Inhalation: Chemical Kinetics and Structural Relaxation Modeling of Exubera Above and Below the Glass Transition Temperature
inferred← citeshttps://doi.org/10.1002/jps.21951openalex-snapshot
Limitations of amorphous content quantification by isothermal calorimetry using saturated salt solutions to control relative humidity: Alternative methods
inferred← citeshttps://doi.org/10.1002/jps.21959openalex-snapshot
The Impact of Thermal Treatment on the Stability of Freeze Dried Amorphous Pharmaceuticals: I. Dimer Formation in Sodium Ethacrynate
inferred← citeshttps://doi.org/10.1002/jps.22009openalex-snapshot
Impact of Counterion on the Chemical Stability of Crystalline Salts of Procaine
inferred← citeshttps://doi.org/10.1002/jps.22074openalex-snapshot
Drug–Polymer Solubility and Miscibility: Stability Consideration and Practical Challenges in Amorphous Solid Dispersion Development
inferred← citeshttps://doi.org/10.1002/jps.22201openalex-snapshot
Editorial
inferred← citeshttps://doi.org/10.1002/jps.22214openalex-snapshot
Crystallization Tendency of Active Pharmaceutical Ingredients Following Rapid Solvent Evaporation—Classification and Comparison with Crystallization Tendency from Under cooled Melts
inferred← citeshttps://doi.org/10.1002/jps.22232openalex-snapshot
Prediction of Onset of Crystallization in Amorphous Pharmaceutical Systems: Phenobarbital, Nifedipine/PVP, and Phenobarbital/PVP
inferred← citeshttps://doi.org/10.1002/jps.22233openalex-snapshot
A Solid-State Approach to Enable Early Development Compounds: Selection and Animsal Bioavailability Studies of an Itraconazole Amorphous Solid Dispersion
inferred← citeshttps://doi.org/10.1002/jps.22236openalex-snapshot
Relative Bioavailability of Three Different Solid Forms of PNU-141659 as Determined with the Artificial Stomach-Duodenum Model
inferred← citeshttps://doi.org/10.1002/jps.22239openalex-snapshot
Use of Enthalpy and Gibbs Free Energy to Evaluate the Risk of Amorphous Formation
inferred← citeshttps://doi.org/10.1002/jps.22242openalex-snapshot
Physicochemical Properties of the Amorphous Drug, Cast Films, and Spray Dried Powders to Predict Formulation Probability of Success for Solid Dispersions: Etravirine
inferred← citeshttps://doi.org/10.1002/jps.22247openalex-snapshot
Physical Stability Studies of Miscible Amorphous Solid Dispersions
inferred← citeshttps://doi.org/10.1002/jps.22313openalex-snapshot
Evaluation of Predictive Models for Stable Solid Solution Formation
inferred← citeshttps://doi.org/10.1002/jps.22387openalex-snapshot
Complex Effects of Drug/Silicate Ratio, Solid-State Equivalent pH, and Moisture on Chemical Stability of Amorphous Quinapril Hydrochloride Coground with Silicates
inferred← citeshttps://doi.org/10.1002/jps.22420openalex-snapshot
Tadalafil Inclusion in Microporous Silica as Effective Dissolution Enhancer: Optimization of Loading Procedure and Molecular State Characterization
inferred← citeshttps://doi.org/10.1002/jps.22429openalex-snapshot
The Inhibition Effect of High Storage Temperature on the Recrystallization Rate During Dissolution of Nimodipine–Kollidon VA64 Solid Dispersions (NM–SD) Prepared by Hot-Melt Extrusion
inferred← citeshttps://doi.org/10.1002/jps.22446openalex-snapshot
Preparation and Characterization of Quercetin Nanocrystals
inferred← citeshttps://doi.org/10.1002/jps.22462openalex-snapshot
Investigation of Atypical Dissolution Behavior of an Encapsulated Amorphous Solid Dispersion
inferred← citeshttps://doi.org/10.1002/jps.22507openalex-snapshot
Solution-Mediated Phase Transformation of Salts During Dissolution: Investigation Using Haloperidol as a Model Drug
inferred← citeshttps://doi.org/10.1002/jps.22519openalex-snapshot
Spontaneous Crystalline-to-Amorphous Phase Transformation of Organic or Medicinal Compounds in the Presence of Porous Media, Part 1: Thermodynamics of Spontaneous Amorphization
inferred← citeshttps://doi.org/10.1002/jps.22585openalex-snapshot
Development of High-Energy Amorphous Solid Dispersion of Nanosized Nobiletin, a Citrus Polymethoxylated Flavone, with Improved Oral Bioavailability
inferred← citeshttps://doi.org/10.1002/jps.22658openalex-snapshot
Physical stability and recrystallization kinetics of amorphous ibipinabant drug product by fourier transform raman spectroscopy
inferred← citeshttps://doi.org/10.1002/jps.22697openalex-snapshot
Moisture content impacts the stability of DNA adsorbed onto gold microparticles
inferred← citeshttps://doi.org/10.1002/jps.22731openalex-snapshot
Comparison of Electrospun and Extruded Soluplus®-Based Solid Dosage Forms of Improved Dissolution
inferred← citeshttps://doi.org/10.1002/jps.22743openalex-snapshot
Barrier Coated Drug Layered Particles for Enhanced Performance of Amorphous Solid Dispersion Dosage Form
inferred← citeshttps://doi.org/10.1002/jps.22779openalex-snapshot
Application of Mesoporous Silicon Dioxide and Silicate in Oral Amorphous Drug Delivery Systems
inferred← citeshttps://doi.org/10.1002/jps.23025openalex-snapshot
Solution-Mediated Phase Transformation: Significance During Dissolution and Implications for Bioavailability
inferred← citeshttps://doi.org/10.1002/jps.23032openalex-snapshot
Solid-State NMR Characterization of High-Loading Solid Solutions of API and Excipients Formed by Electrospinning
inferred← citeshttps://doi.org/10.1002/jps.23035openalex-snapshot
Milling-Induced Disorder of Pharmaceuticals: One-Phase or Two-Phase System?
inferred← citeshttps://doi.org/10.1002/jps.23075openalex-snapshot
Miscibility Studies of Indomethacin and Eudragit® E PO by Thermal, Rheological, and Spectroscopic Analysis
inferred← citeshttps://doi.org/10.1002/jps.23107openalex-snapshot
Solid-State Nuclear Magnetic Resonance Study of the Physical Stability of Electrospun Drug and Polymer Solid Solutions
inferred← citeshttps://doi.org/10.1002/jps.23125openalex-snapshot
Amorphous-State Characterization of Efavirenz—Polymer Hot-Melt Extrusion Systems for Dissolution Enhancement
inferred← citeshttps://doi.org/10.1002/jps.23131openalex-snapshot
Nanoscale Surface Characterization and Miscibility Study of a Spray-Dried Injectable Polymeric Matrix Consisting of Poly(lactic-co-glycolic acid) and Polyvinylpyrrolidone
inferred← citeshttps://doi.org/10.1002/jps.23147openalex-snapshot
Estimation of Crystallinity of Trehalose Dihydrate Microspheres by Usage of Terahertz Time-Domain Spectroscopy
inferred← citeshttps://doi.org/10.1002/jps.23280openalex-snapshot
Nonlinear Optical Imaging for Sensitive Detection of Crystals in Bulk Amorphous Powders
inferred← citeshttps://doi.org/10.1002/jps.23353openalex-snapshot
Molecular Dynamics Simulation of Amorphous Indomethacin-Poly(Vinylpyrrolidone) Glasses: Solubility and Hydrogen Bonding Interactions
inferred← citeshttps://doi.org/10.1002/jps.23358openalex-snapshot
Crystallization of Amorphous Solid Dispersions of Resveratrol during Preparation and Storage—Impact of Different Polymers
inferred← citeshttps://doi.org/10.1002/jps.23475openalex-snapshot
Performance Comparison of two Novel Combinative Particle-Size-Reduction Technologies
inferred← citeshttps://doi.org/10.1002/jps.23481openalex-snapshot
Editorial
inferred← citeshttps://doi.org/10.1002/jps.23553openalex-snapshot
An Augmented Volume-Based Model of the Glass Transition Temperature of 209 Molecular Liquids
inferred← citeshttps://doi.org/10.1002/jps.23723openalex-snapshot
Application of Gas Pycnometry for the Density Measurement of Freeze-Dried Products
inferred← citeshttps://doi.org/10.1002/jps.23731openalex-snapshot
Solid Dispersions Prepared by Continuous Cogrinding in an Air Jet Mill
inferred← citeshttps://doi.org/10.1002/jps.23855openalex-snapshot
Water Uptake, Distribution, and Mobility in Amorphous Poly( d , l ‐Lactide) by Molecular Dynamics Simulation
inferred← citeshttps://doi.org/10.1002/jps.23896openalex-snapshot
Formulation, Preparation, and Evaluation of Novel Orally Disintegrating Tablets Containing Taste-Masked Naproxen Sodium Granules and Naratriptan Hydrochloride
inferred← citeshttps://doi.org/10.1002/jps.23930openalex-snapshot
Critical Considerations for the Qualitative and Quantitative Determination of Process‐Induced Disorder in Crystalline Solids
inferred← citeshttps://doi.org/10.1002/jps.23966openalex-snapshot
Structural and Dynamic Properties of Amorphous Solid Dispersions: The Role of Solid-State Nuclear Magnetic Resonance Spectroscopy and Relaxometry
inferred← citeshttps://doi.org/10.1002/jps.24009openalex-snapshot
Water Clusters in Amorphous Pharmaceuticals
inferred← citeshttps://doi.org/10.1002/jps.24016openalex-snapshot
Crystallization from the Amorphous State: Nucleation–Growth Decoupling, Polymorphism Interplay, and the Role of Interfaces
inferred← citeshttps://doi.org/10.1002/jps.24021openalex-snapshot
The Importance of Individual Protein Molecule Dynamics in Developing and Assessing Solid State Protein Preparations
inferred← citeshttps://doi.org/10.1002/jps.24027openalex-snapshot
Sucrose/Glucose Molecular Alloys by Cryomilling
inferred← citeshttps://doi.org/10.1002/jps.24050openalex-snapshot
Effects of Formulation and Process Factors on the Crystal Structure of Freeze-Dried Myo-Inositol
inferred← citeshttps://doi.org/10.1002/jps.24109openalex-snapshot
Editorial
inferred← citeshttps://doi.org/10.1002/jps.24160openalex-snapshot
Dynamic Vapor Sorption as a Tool for Characterization and Quantification of Amorphous Content in Predominantly Crystalline Materials
inferred← citeshttps://doi.org/10.1002/jps.24199openalex-snapshot
Oral Delivery of Highly Lipophilic Poorly Water-Soluble Drugs: Spray-Dried Dispersions to Improve Oral Absorption and Enable High-Dose Toxicology Studies of a P2Y1 Antagonist
inferred← citeshttps://doi.org/10.1002/jps.24207openalex-snapshot
Evaluation of Drug–Polymer Solubility Curves Through Formal Statistical Analysis: Comparison of Preparation Techniques
inferred← citeshttps://doi.org/10.1002/jps.24410openalex-snapshot
Influence of Polymer Molecular Weight on Drug–polymer Solubility: A Comparison between Experimentally Determined Solubility in PVP and Prediction Derived from Solubility in Monomer
inferred← citeshttps://doi.org/10.1002/jps.24423openalex-snapshot
Trends in the Precipitation and Crystallization Behavior of Supersaturated Aqueous Solutions of Poorly Water-Soluble Drugs Assessed Using Synchrotron Radiation
inferred← citeshttps://doi.org/10.1002/jps.24541openalex-snapshot
Amorphous Solid Dispersions: Utilization and Challenges in Drug Discovery and Development
inferred← citeshttps://doi.org/10.1002/jps.24574openalex-snapshot
Formulation Design of Dry Powders for Inhalation
inferred← citeshttps://doi.org/10.1002/jps.24589openalex-snapshot
Deliquescence: Hygroscopicity of Water-Soluble Crystalline Solids
inferred← citeshttps://doi.org/10.1002/jps.24671openalex-snapshot
Estimation of Crystallinity of Nifedipine–Polyvinylpyrrolidone Solid Dispersion by Usage of Terahertz Time-Domain Spectroscopy and of X-Ray Powder Diffractometer
inferred← citeshttps://doi.org/10.1002/jrs.1134openalex-snapshot
A theoretical and spectroscopic study of carbamazepine polymorphs
inferred← citeshttps://doi.org/10.1002/jrs.1140openalex-snapshot
Quantitative analysis of polymorphic mixtures of carbamazepine by Raman spectroscopy and principal components analysis
inferred← citeshttps://doi.org/10.1002/jrs.1158openalex-snapshot
Polyethylene oxides: protection potential against polymorphic transitions of drugs?
inferred← citeshttps://doi.org/10.1002/jsfa.71114openalex-snapshot
Amorphization and microencapsulation of β ‐carotene with improved physical stability and bioaccessibility for emulsion‐based 3D printing
inferred← citeshttps://doi.org/10.1002/jsfa.8154openalex-snapshot
Water dynamics of Ser‐His‐Glu‐Cys‐Asn powder and effects of moisture absorption on its chemical properties
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