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The Salt−Cocrystal Continuum: The Influence of Crystal Structure on Ionization State
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Outgoing claims: the papers this work cites, builds on, or argues with.
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inferred← citeshttps://doi.org/10.1007/s11095-018-2343-3openalex-snapshot
Cocrystal Solubility Product Prediction Using an in combo Model and Simulations to Improve Design of Experiments
inferred← citeshttps://doi.org/10.1007/s11095-022-03305-yopenalex-snapshot
Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids
inferred← citeshttps://doi.org/10.1007/s11224-013-0326-xopenalex-snapshot
Transforming aspirin into novel molecular salts of salicylic acid
inferred← citeshttps://doi.org/10.1007/s11224-021-01805-yopenalex-snapshot
The SN2 reaction and its relationship with the Walden inversion, the Finkelstein and Menshutkin reactions together with theoretical calculations for the Finkelstein reaction
inferred← citeshttps://doi.org/10.1007/s11426-011-4412-xopenalex-snapshot
Phenylboronic acids in crystal engineering: Utility of the energetically unfavorable syn,syn-conformation in co-crystal design
inferred← citeshttps://doi.org/10.1007/s11426-012-4701-zopenalex-snapshot
Three-dimensional supramolecular architecture based on 4,4′-methylene-bis(benzenamine) and aromatic carboxylic acid guests: Synthons cooperation, robust motifs and structural diversity
inferred← citeshttps://doi.org/10.1007/s11426-014-5101-3openalex-snapshot
Trimer formation of 6-methyl-1,3,5-triazine-2,4-diamine in salt with organic and inorganic acids: analysis of supramolecular architecture
inferred← citeshttps://doi.org/10.1007/s12039-013-0376-zopenalex-snapshot
1-Phenyl-3-(quinolin-5-yl)urea as a host for distinction of phthalic acid and terephthalic acid
inferred← citeshttps://doi.org/10.1007/s12039-014-0698-5openalex-snapshot
New co-crystal and salt form of sulfathiazole with carboxylic acid and amide
inferred← citeshttps://doi.org/10.1007/s12247-018-9361-xopenalex-snapshot
Ionic Liquid Forms of Carvedilol: Preparation, Characterization, and Solubility Studies
inferred← citeshttps://doi.org/10.1007/s40010-014-0123-yopenalex-snapshot
Design Aspects of Luminescent Organic Crystals
inferred← citeshttps://doi.org/10.1007/s41745-017-0028-2openalex-snapshot
Polymorphs and Cocrystals: A Comparative Analysis
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.12598-3openalex-snapshot
Hydrogen Bonding in Molecular Crystals
inferred← citeshttps://doi.org/10.1016/b978-0-12-802447-8.00004-2openalex-snapshot
API Solid-Form Screening and Selection
inferred← citeshttps://doi.org/10.1016/b978-0-12-814423-7.00015-0openalex-snapshot
Solubility and Solubilization Approaches in Pharmaceutical Product Development
inferred← citeshttps://doi.org/10.1016/b978-0-443-34156-4.00002-9openalex-snapshot
Active pharmaceutical ingredient solid form screening and selection
inferred← citeshttps://doi.org/10.1016/bs.arnmr.2021.02.002openalex-snapshot
Fast and very fast MAS solid state NMR studies of pharmaceuticals
inferred← citeshttps://doi.org/10.1016/bs.pmch.2021.05.001openalex-snapshot
An industrial perspective on co-crystals: Screening, identification and development of the less utilised solid form in drug discovery and development
inferred← citeshttps://doi.org/10.1016/j.addr.2017.03.003openalex-snapshot
Pharmaceutical cocrystals, salts and multicomponent systems; intermolecular interactions and property based design
inferred← citeshttps://doi.org/10.1016/j.addr.2017.07.001openalex-snapshot
Pharmaceutical aspects of salt and cocrystal forms of APIs and characterization challenges
inferred← citeshttps://doi.org/10.1016/j.ajps.2013.07.003openalex-snapshot
Theophylline–citric acid co-crystals easily induced by DSC–FTIR microspectroscopy or different storage conditions
inferred← citeshttps://doi.org/10.1016/j.cclet.2017.09.049openalex-snapshot
Drug-polymer inclusion complex as a new pharmaceutical solid form
inferred← citeshttps://doi.org/10.1016/j.cclet.2024.110413openalex-snapshot
Reaction crystallization method based on deep eutectic solvents: A novel, green and efficient cocrystal synthesis approach
inferred← citeshttps://doi.org/10.1016/j.ccr.2024.216035openalex-snapshot
Current trends and advancements in crystallization and single-crystal structural analysis of small molecules
inferred← citeshttps://doi.org/10.1016/j.cej.2025.171386openalex-snapshot
Hydrogen-bonded organic frameworks (HOFs): Beyond the bond—Crystal engineering concept for designing advanced delivery systems and therapeutic agents
inferred← citeshttps://doi.org/10.1016/j.ces.2011.12.007openalex-snapshot
Synthesis, crystallization and characterization of diastereomeric salts formed by ephedrine and malic acid in water
inferred← citeshttps://doi.org/10.1016/j.ces.2022.117549openalex-snapshot
Norfloxacin co-amorphous salt systems: Effects of molecular descriptors on the formation and physical stability of co-amorphous systems
inferred← citeshttps://doi.org/10.1016/j.ces.2026.125347openalex-snapshot
Population balance modeling in the salt–cocrystal continuum: from kinetic identification to a model-based design space
inferred← citeshttps://doi.org/10.1016/j.cherd.2024.08.017openalex-snapshot
Ternary phase diagram and investigation of slurry conversion of 1:1 sulfamethazine-acetylsalicylic acid cocrystal
inferred← citeshttps://doi.org/10.1016/j.cplett.2022.139746openalex-snapshot
Theoretical insights into the linear relationship between pK a values and vibrational frequencies
inferred← citeshttps://doi.org/10.1016/j.cplett.2023.140654openalex-snapshot
The pKa rule in light of local mode force constants
inferred← citeshttps://doi.org/10.1016/j.cplett.2024.141772openalex-snapshot
Thiabendazole: Fumaric acid as a case study on the salt cocrystal continuum: A local vibrational mode perspective
inferred← citeshttps://doi.org/10.1016/j.drudis.2008.03.004openalex-snapshot
The role of cocrystals in pharmaceutical science
inferred← citeshttps://doi.org/10.1016/j.drudis.2016.02.001openalex-snapshot
Multidrug co-crystals: towards the development of effective therapeutic hybrids
inferred← citeshttps://doi.org/10.1016/j.ejmech.2008.03.012openalex-snapshot
Molecular structure and stability of perindopril erbumine and perindopril l-arginine complexes
inferred← citeshttps://doi.org/10.1016/j.ejmech.2013.11.045openalex-snapshot
Pharmaceutical salts and cocrystals involving amino acids: A brief structural overview of the state-of-art
inferred← citeshttps://doi.org/10.1016/j.ejpb.2013.09.010openalex-snapshot
In situ amorphisation of indomethacin with Eudragit® E during dissolution
inferred← citeshttps://doi.org/10.1016/j.ejpb.2018.07.016openalex-snapshot
Organic acids as co-formers for co-amorphous systems – Influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems
inferred← citeshttps://doi.org/10.1016/j.ejpb.2020.05.031openalex-snapshot
Structure-mechanics and improved tableting performance of the drug-drug cocrystal metformin:salicylic acid
inferred← citeshttps://doi.org/10.1016/j.ejpb.2022.04.002openalex-snapshot
Combining enabling formulation strategies to generate supersaturated solutions of delamanid: In situ salt formation during amorphous solid dispersion fabrication for more robust release profiles
inferred← citeshttps://doi.org/10.1016/j.ejpb.2024.114344openalex-snapshot
Enantiospecific crystallisation behaviour of malic acid in mechanochemical reactions with vinpocetine
inferred← citeshttps://doi.org/10.1016/j.ejpb.2026.115217openalex-snapshot
Towards macrophage-oriented Antituberculosis therapy: nanohydrogel and liposomal delivery of rifampicin–berberine Co-nanocrystals for enhanced intracellular Antituberculosis activity
inferred← citeshttps://doi.org/10.1016/j.ejps.2015.06.004openalex-snapshot
Pharmaceutical salts of ciprofloxacin with dicarboxylic acids
inferred← citeshttps://doi.org/10.1016/j.ejps.2015.10.006openalex-snapshot
Mechanism study on stability enhancement of adefovir dipivoxil by cocrystallization: Degradation kinetics and structure-stability correlation
inferred← citeshttps://doi.org/10.1016/j.ejps.2015.10.007openalex-snapshot
Mechanochemistry applied to reformulation and scale-up production of Ethionamide: Salt selection and solubility enhancement
inferred← citeshttps://doi.org/10.1016/j.ejps.2016.01.029openalex-snapshot
Improving the solubility of dexlansoprazole by cocrystallization with isonicotinamide
inferred← citeshttps://doi.org/10.1016/j.ejps.2016.10.035openalex-snapshot
Pharmaceutical salts of ethionamide with GRAS counter ion donors to enhance the solubility
inferred← citeshttps://doi.org/10.1016/j.ejps.2019.104981openalex-snapshot
Continuous, simultaneous cocrystallization and formulation of Theophylline and 4-Aminobenzoic acid pharmaceutical cocrystals using twin screw melt granulation
inferred← citeshttps://doi.org/10.1016/j.ejps.2023.106503openalex-snapshot
Polymorphs of a 1:1 salt of sulfadiazine and piperazine–relative stability, dissolution studies, pharmacokinetics and anti-meningitis efficiency
inferred← citeshttps://doi.org/10.1016/j.fluid.2016.05.016openalex-snapshot
Ketoconazole ionic liquids with citric and tartaric acid: Synthesis, characterization and solubility study
inferred← citeshttps://doi.org/10.1016/j.heliyon.2022.e11872openalex-snapshot
Pharmaceutical Cocrystal of Antibiotic Drugs: A Comprehensive Review
inferred← citeshttps://doi.org/10.1016/j.heliyon.2026.e45278openalex-snapshot
Favipiravir - Moxifloxacin ionic interaction to form a new antiviral – Antibiotic multicomponent system with the stability, potency, and safety enhancement
inferred← citeshttps://doi.org/10.1016/j.ica.2012.01.049openalex-snapshot
Comparative study on two novel nine-coordinated supramolecular compounds of cerium(III) and yttrium(III): Solid and solution states studies
inferred← citeshttps://doi.org/10.1016/j.ica.2014.12.006openalex-snapshot
Stabilisation of true π-electron–π-electron interactions in an inorganic cocrystal
inferred← citeshttps://doi.org/10.1016/j.ica.2015.08.030openalex-snapshot
Two new copper and nickel complexes of pyridine-2,6-dicarboxylic acid N-oxide and their proton transferred salts: Solid state and DFT insights
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2009.03.016openalex-snapshot
Modeling and prediction of cocrystal phase diagrams
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2010.07.055openalex-snapshot
High-throughput cocrystal slurry screening by use of in situ Raman microscopy and multi-well plate
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2010.12.011openalex-snapshot
Application of mid-IR spectroscopy for the characterization of pharmaceutical systems
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2011.03.063openalex-snapshot
Computational prediction of salt and cocrystal structures—Does a proton position matter?
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2011.08.032openalex-snapshot
Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2011.09.034openalex-snapshot
Characterization and evaluation of miconazole salts and cocrystals for improved physicochemical properties
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2012.09.045openalex-snapshot
Fast dissolving eutectic compositions of curcumin
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2012.10.043openalex-snapshot
Pharmaceutical cocrystals and poorly soluble drugs
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2012.11.028openalex-snapshot
Use of pharmaceutical salts and cocrystals to address the issue of poor solubility
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2013.03.040openalex-snapshot
Quantification of protonation in organic solvents using solution NMR spectroscopy: Implication in salt formation
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2014.07.008openalex-snapshot
Novel pharmaceutical cocrystal consisting of paracetamol and trimethylglycine, a new promising cocrystal former
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2017.09.063openalex-snapshot
Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2019.118774openalex-snapshot
Human volunteer, in vitro, and molecular level evaluation of an optimized taste-masked isoniazid-chitosan spray-dried microparticle matrix
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2019.118942openalex-snapshot
Cocrystals of diacerein: Towards the development of improved biopharmaceutical parameters
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2020.119694openalex-snapshot
Enhancing the solubility and permeability of the diuretic drug furosemide via multicomponent crystal forms
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120228openalex-snapshot
Estimating the maximal solubility advantage of drug salts
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120292openalex-snapshot
Stabilising disproportionation of lipophilic ionic liquid salts in lipid-based formulations
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120605openalex-snapshot
Characterisation and fundamental insight into the formation of new solid state, multicomponent systems of propranolol
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120790openalex-snapshot
Multicomponent ionic crystals of diltiazem with dicarboxylic acids toward understanding the structural aspects driving the drug-release
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.121460openalex-snapshot
Improving the dissolution behaviors and bioavailability of abiraterone acetate via multicomponent crystal forms
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.122310openalex-snapshot
Discovered two polymorphs and two solvates of lamotrigine-tolfenamic acid salt: Thermal behavior and crystal morphological differences
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.122461openalex-snapshot
Rucaparib cocrystal: Improved solubility and bioavailability over camsylate
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.122645openalex-snapshot
Poly (amino acid)s as new co-formers in amorphous solid dispersion
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.123053openalex-snapshot
Crystalline and amorphous famotidine malate as pathways to prevent polymorphic transformation with improved dissolution
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.123501openalex-snapshot
Design, synthesis and characterization of a novel multicomponent salt of bexarotene with metformin and application in ameliorating psoriasis with T2DM
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.123516openalex-snapshot
Soluble thiabendazolium salts with anthelminthic properties
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.123855openalex-snapshot
Preparation and characterization of new salts of tioconazole. Comparison of their dissolution performance
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.123939openalex-snapshot
Cocrystallization improves the tabletability of ligustrazine despite a reduction in plasticity
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.124959openalex-snapshot
Towards the discovery of unrevealed flufenamic acid cocrystals via structural resemblance for enhanced topical drug delivery
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.125255openalex-snapshot
Direct compression tablet formulation of trimetazidine through systematic screening of oxalate salts
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.125338openalex-snapshot
Calculating pH-solubility profile and pHmax for monoprotic salts of poorly water-soluble weak bases
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.126454openalex-snapshot
Electrosprayed co-crystals of levofloxacin for inhalation: a strategy for excipient-free dry powder antibiotics
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.126482openalex-snapshot
Combining crystal engineering and surface engineering to estimate the structure -functions relationship of Tafamidis solid state forms with the aid of machine learning
inferred← citeshttps://doi.org/10.1016/j.inoche.2025.115916openalex-snapshot
New coordination modes of furosemide anion in copper(II) complexes: synthesis and structural insights
inferred← citeshttps://doi.org/10.1016/j.jconrel.2026.115277openalex-snapshot
Pharmaceutical cocrystals beyond enteral drug delivery: from concept to translation
inferred← citeshttps://doi.org/10.1016/j.jcrysgro.2010.12.027openalex-snapshot
Cocrystal formation in solution: Inducing phase transition by manipulating the amount of cocrystallizing agent
inferred← citeshttps://doi.org/10.1016/j.jcrysgro.2011.09.032openalex-snapshot
Pharmaceutical cocrystals: a comparison of sulfamerazine with sulfamethazine
inferred← citeshttps://doi.org/10.1016/j.jcrysgro.2012.01.059openalex-snapshot
Crystal growth and physical characterization of picolinic acid cocrystallized with dicarboxylic acids
inferred← citeshttps://doi.org/10.1016/j.jcrysgro.2013.03.007openalex-snapshot
Investigation of supramolecular synthons of p-hydroxybenzoic acid (PHBA): Comparison of its hydrate, co-crystal and salt
inferred← citeshttps://doi.org/10.1016/j.jct.2017.02.019openalex-snapshot
Effect of pH in the structure and mass transport by diffusion of theophylline
inferred← citeshttps://doi.org/10.1016/j.jddst.2016.02.003openalex-snapshot
Glass solution formation in water - In situ amorphization of naproxen and ibuprofen with Eudragit® E PO
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