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Geopyxins A–E, ent-Kaurane Diterpenoids from Endolichenic Fungal Strains Geopyxis aff. majalis and Geopyxis sp. AZ0066: Structure–Activity Relationships of Geopyxins and Their Analogues

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s00248-010-9698-2openalex-snapshot
Community Analysis Reveals Close Affinities Between Endophytic and Endolichenic Fungi in Mosses and Lichens
inferredcites →https://doi.org/10.1007/s12192-010-0206-xopenalex-snapshot
Xenohormesis: health benefits from an eon of plant stress response evolution
inferredcites →https://doi.org/10.1016/j.bmc.2008.10.091openalex-snapshot
2,3-Dihydrowithaferin A-3β-O-sulfate, a new potential prodrug of withaferin A from aeroponically grown Withania somnifera
inferredcites →https://doi.org/10.1016/j.cbpa.2010.11.003openalex-snapshot
Proteomic approaches to the characterization of protein thiol modification
inferredcites →https://doi.org/10.1016/j.cell.2007.07.020openalex-snapshot
Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis
inferredcites →https://doi.org/10.1016/j.cell.2008.04.019openalex-snapshot
Xenohormesis: Sensing the Chemical Cues of Other Species
inferredcites →https://doi.org/10.1016/j.mycres.2007.03.014openalex-snapshot
A phylogenetic overview of the family Pyronemataceae (Ascomycota, Pezizales)
inferredcites →https://doi.org/10.1016/j.ympev.2005.03.010openalex-snapshot
Evolutionary relationships of the cup-fungus genus Peziza and Pezizaceae inferred from multiple nuclear genes: RPB2, β-tubulin, and LSU rDNA
inferredcites →https://doi.org/10.1016/s0040-4039(00)80593-6openalex-snapshot
Absolute configurations of cytotoxic marine cembranolides; Consideration of mosher's method
inferredcites →https://doi.org/10.1021/ja00011a006openalex-snapshot
High-field FT NMR application of Mosher's method. The absolute configurations of marine terpenoids
inferredcites →https://doi.org/10.1021/ja01613a080openalex-snapshot
The Effect of Ring Strain on the Ultraviolet Spectra of α,β-Unsaturated Carbonyl Compounds
inferredcites →https://doi.org/10.1021/jf070734wopenalex-snapshot
Isolation of Two Bioactiveent-Kauranoids from the Leaves ofIsodon xerophilus
inferredcites →https://doi.org/10.1021/jo00868a023openalex-snapshot
New hydroxylated ent-kauranoic acids from Eupatorium album
inferredcites →https://doi.org/10.1021/np020059eopenalex-snapshot
Cytotoxic 3,20-Epoxy-ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora
inferredcites →https://doi.org/10.1021/np0304114openalex-snapshot
Ponicidin and Oridonin Are Responsible for the Antiangiogenic Activity of Rabdosia rubescens, a Constituent of the Herbal Supplement PC SPES
inferredcites →https://doi.org/10.1021/np058095bopenalex-snapshot
Search for Hsp90 Inhibitors with Potential Anticancer Activity: Isolation and SAR Studies of Radicicol and Monocillin I from Two Plant-Associated Fungi of the Sonoran Desert
inferredcites →https://doi.org/10.1021/np060504wopenalex-snapshot
Cytotoxic Activity of Some Natural and Synthetic ent-Kauranes
inferredcites →https://doi.org/10.1021/np070205mopenalex-snapshot
Cytotoxic ent-Kauranoids from the Medicinal Plant Isodon xerophilus
inferredcites →https://doi.org/10.1021/np070466wopenalex-snapshot
Heptaketides from Corynespora sp. Inhabiting the Cavern Beard Lichen, Usnea cavernosa: First Report of Metabolites of an Endolichenic Fungus
inferredcites →https://doi.org/10.1021/np100071zopenalex-snapshot
Oxepinochromenones, Furochromenone, and their Putative Precursors from the Endolichenic Fungus Coniochaeta sp.
inferredcites →https://doi.org/10.1021/np100159jopenalex-snapshot
Absolute Configuration of Brevisamide and Brevisin: Confirmation of a Universal Biosynthetic Process for Karenia brevis Polyethers
inferredcites →https://doi.org/10.1021/np2000864openalex-snapshot
Smardaesidins A–G, Isopimarane and 20-nor-Isopimarane Diterpenoids from Smardaea sp., a Fungal Endophyte of the Moss Ceratodon purpureus
inferredcites →https://doi.org/10.1021/np8003062openalex-snapshot
ent-Kaurane Diterpenoids from the Liverwort Jungermannia atrobrunnea
inferredcites →https://doi.org/10.1021/np800671popenalex-snapshot
Antioxidant and Anticholinesterase Activity Evaluation of ent -Kaurane Diterpenoids from Sideritis arguta
inferredcites →https://doi.org/10.1021/np800733yopenalex-snapshot
Ambuic Acid and Torreyanic Acid Derivatives from the Endolichenic Fungus Pestalotiopsis sp.
inferredcites →https://doi.org/10.1021/np9001465openalex-snapshot
Inhibition of NF-κB Activation and iNOS Induction by ent-Kaurane Diterpenoids in LPS-Stimulated RAW264.7 Murine Macrophages
inferredcites →https://doi.org/10.1021/np900250kopenalex-snapshot
Cytotoxic Diterpenoids from Croton argyrophylloides
inferredcites →https://doi.org/10.1021/np900512kopenalex-snapshot
Allenyl and Alkynyl Phenyl Ethers from the Endolichenic Fungus Neurospora terricola
inferredcites →https://doi.org/10.1021/np9903705openalex-snapshot
New 7,20:14,20-Diepoxy ent-Kauranoids from Isodon xerophilus
inferredcites →https://doi.org/10.1021/ol102168zopenalex-snapshot
The First Naturally Occurring Thiepinols and Thienol from an Endolichenic Fungus Coniochaeta sp.
inferredcites →https://doi.org/10.1021/tx050312lopenalex-snapshot
Cytosolic and Nuclear Protein Targets of Thiol-Reactive Electrophiles
inferredcites →https://doi.org/10.1038/nature09472openalex-snapshot
Quantitative reactivity profiling predicts functional cysteines in proteomes
inferredcites →https://doi.org/10.1039/p19840002363openalex-snapshot
Carbon-13 nuclear magnetic resonance spectra of eighteen derivatives of ent-kaur-16-en-19-oic acid
inferredcites →https://doi.org/10.1046/j.1432-1327.2000.01606.xopenalex-snapshot
Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
inferredcites →https://doi.org/10.1055/s-0029-1186002openalex-snapshot
Ent -Kaurane Diterpenoids from Rabdosia rubescens and Their Cytotoxic Effects on Human Cancer Cell Lines
inferredcites →https://doi.org/10.1055/s-0029-1240683openalex-snapshot
Anti-HIV‐1 Diterpenoids from Leaves and Twigs ofPolyalthia sclerophylla
inferredcites →https://doi.org/10.1055/s-0029-1240863openalex-snapshot
SIRT1 Inhibitory Diterpenoids from the Vietnamese Medicinal PlantCroton tonkinensis
inferredcites →https://doi.org/10.1055/s-2001-15808openalex-snapshot
Kaurane Diterpenes from Isodon japonicus Inhibit Nitric Oxide and Prostaglandin E2 Production and NF-κB Activation in LPS-Stimulated Macrophage RAW264.7 Cells
inferredcites →https://doi.org/10.1055/s-2005-871234openalex-snapshot
An Anti-Inflammatoryent-Kaurane from the Stems ofAnnona squamosathat Inhibits Various Human Neutrophil Functions
inferredcites →https://doi.org/10.1073/pnas.1014714108openalex-snapshot
Identity, regulation, and activity of inducible diterpenoid phytoalexins in maize
inferredcites →https://doi.org/10.1093/bioinformatics/14.9.817openalex-snapshot
MODELTEST: testing the model of DNA substitution.
inferredcites →https://doi.org/10.1271/bbb.70.583openalex-snapshot
Biochemical and Molecular Analyses of Gibberellin Biosynthesis in Fungi
inferredcites →https://doi.org/10.25911/5d6c3f290bb26openalex-snapshot
Studies in natural products chemistry
inferredcites →https://doi.org/10.3390/12030455openalex-snapshot
Occurrence, Biological Activities and Synthesis of Kaurane Diterpenes and their Glycosides

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Non-Covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation
inferred← citeshttps://doi.org/10.1002/cbdv.201400146openalex-snapshot
Identification and Biological Evaluation of Secondary Metabolites from the Endolichenic Fungus Aspergillus versicolor
inferred← citeshttps://doi.org/10.1002/cbdv.201400279openalex-snapshot
New Metabolites from Endolichenic Fungus Pleosporales sp.
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Secondary Metabolites from Aspergillus fumigatus, an Endophytic Fungus from the Liverwort Heteroscyphus tener ( Steph .) Schiffn .
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Marine-Derived Fungal Metabolites
inferred← citeshttps://doi.org/10.1007/978-981-13-7154-7_4openalex-snapshot
Endolichenic Fungi from Common Lichens as New Sources for Valuable Bio-active Compounds
inferred← citeshttps://doi.org/10.1007/978-981-13-7268-1_5openalex-snapshot
Endolichenic Fungi: A Promising Source for Novel Bioactive Compounds
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Semi-synthesis and cytotoxicity evaluation of pyrimidine, thiazole, and indole analogues of argentatins A–C from guayule (Parthenium argentatum) resin
inferred← citeshttps://doi.org/10.1007/s10600-015-1305-9openalex-snapshot
A New Fatty Acid from the Endolichenic Fungus Massarina sp.
inferred← citeshttps://doi.org/10.1007/s11101-016-9473-1openalex-snapshot
Endolichenic fungi: a new source of rich bioactive secondary metabolites on the horizon
inferred← citeshttps://doi.org/10.1007/s11101-018-9577-xopenalex-snapshot
Have lichenized fungi delivered promising anticancer small molecules?
inferred← citeshttps://doi.org/10.1007/s40203-026-00633-4openalex-snapshot
Antiproliferative activity of Xylopia aethiopica extracts and molecular docking studies of their main phytochemicals
inferred← citeshttps://doi.org/10.1016/b978-0-12-809633-8.21118-7openalex-snapshot
Antitumor and Immunomodulatory Compounds from Fungi
inferred← citeshttps://doi.org/10.1016/b978-0-444-63602-7.00011-4openalex-snapshot
Endolichenic Fungi
inferred← citeshttps://doi.org/10.1016/j.bmc.2014.08.039openalex-snapshot
Altertoxins with potent anti-HIV activity from Alternaria tenuissima QUE1Se, a fungal endophyte of Quercus emoryi
inferred← citeshttps://doi.org/10.1016/j.chembiol.2019.07.011openalex-snapshot
Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation
inferred← citeshttps://doi.org/10.1016/j.fitote.2022.105160openalex-snapshot
Discovery of ent-kaurane diterpenoids, characteristic metabolites of Isodon species, from an endophytic fungal strain Geopyxis sp. XY93 inhabiting Isodon parvifolia
inferred← citeshttps://doi.org/10.1016/j.phymed.2018.01.006openalex-snapshot
Acetonic extracts of the endolichenic fungus EL002332 isolated from Endocarpon pusillum exhibits anticancer activity in human gastric cancer cells
inferred← citeshttps://doi.org/10.1016/j.phytochem.2015.08.010openalex-snapshot
Sesquiterpenes and other constituents of Xylaria sp. NC1214, a fungal endophyte of the moss Hypnum sp.
inferred← citeshttps://doi.org/10.1016/j.phytol.2013.08.011openalex-snapshot
Austdiol, fulvic acid and citromycetin derivatives from an endolichenic fungus, Myxotrichum sp.
inferred← citeshttps://doi.org/10.1016/j.phytol.2018.10.011openalex-snapshot
Modulation of polyketide biosynthetic pathway of the endophytic fungus, Anteaglonium sp. FL0768, by copper (II) and anacardic acid
inferred← citeshttps://doi.org/10.1016/j.redox.2021.101977openalex-snapshot
ent-Kaurane diterpenoids induce apoptosis and ferroptosis through targeting redox resetting to overcome cisplatin resistance
inferred← citeshttps://doi.org/10.1016/j.sajb.2019.12.008openalex-snapshot
Endolichenic fungi: A hidden source of bioactive metabolites
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5b00208openalex-snapshot
ent-Kaurane Diterpenoids from Chinese Liverworts and Their Antitumor Activities through Michael Addition As Detected in Situ by a Fluorescence Probe
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.1c00662openalex-snapshot
Strobiloscyphones A–F, 6-Isopentylsphaeropsidones and Other Metabolites from Strobiloscypha sp. AZ0266, a Leaf-Associated Fungus of Douglas Fir
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5b00911openalex-snapshot
17β-Hydroxy-18-acetoxywithanolides from Aeroponically Grown Physalis crassifolia and Their Potent and Selective Cytotoxicity for Prostate Cancer Cells
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b00197openalex-snapshot
p-Terphenyl Derivatives from the Endolichenic Fungus Floricola striata
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b00960openalex-snapshot
Chlorinated Dehydrocurvularins and Alterperylenepoxide A from Alternaria sp. AST0039, a Fungal Endophyte of Astragalus lentiginosus
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b00838openalex-snapshot
Cytotoxic and Noncytotoxic Metabolites from Teratosphaeria sp. FL2137, a Fungus Associated with Pinus clausa
inferred← citeshttps://doi.org/10.1021/acs.orglett.9b00385openalex-snapshot
Isocoumarindole A, a Chlorinated Isocoumarin and Indole Alkaloid Hybrid Metabolite from an Endolichenic Fungus Aspergillus sp.
inferred← citeshttps://doi.org/10.1021/acsomega.1c01714openalex-snapshot
Cycloartane- and Lanostane-Type Triterpenoids from the Resin of Parthenium argentatum AZ-2, a Byproduct of Guayule Rubber Production
inferred← citeshttps://doi.org/10.1021/np300106jopenalex-snapshot
Laxiflorolides A and B, Epimeric Bishomoditerpene Lactones from Isodon eriocalyx
inferred← citeshttps://doi.org/10.1021/np300792topenalex-snapshot
Mycoleptodiscins A and B, Cytotoxic Alkaloids from the Endophytic Fungus Mycoleptodiscus sp. F0194
inferred← citeshttps://doi.org/10.1021/np400391popenalex-snapshot
Phomapyrrolidones A–C, Antitubercular Alkaloids from the Endophytic Fungus Phoma sp. NRRL 46751
inferred← citeshttps://doi.org/10.1021/np400762kopenalex-snapshot
Secoemestrin D, a Cytotoxic Epitetrathiodioxopiperizine, and Emericellenes A–E, Five Sesterterpenoids from Emericella sp. AST0036, a Fungal Endophyte of Astragalus lentiginosus1
inferred← citeshttps://doi.org/10.1021/ol502973copenalex-snapshot
Delitschiapyrone A, a Pyrone–Naphthalenone Adduct Bearing a New Pentacyclic Ring System from the Leaf-Associated Fungus Delitschia sp. FL1581
inferred← citeshttps://doi.org/10.1038/s41429-018-0058-7openalex-snapshot
Anti-inflammatory phomalichenones from an endolichenic fungus Phoma sp.
inferred← citeshttps://doi.org/10.1038/srep41273openalex-snapshot
A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability
inferred← citeshttps://doi.org/10.1039/c3np70046aopenalex-snapshot
Diterpenoids of terrestrial origin
inferred← citeshttps://doi.org/10.1039/c4np00075gopenalex-snapshot
Traversing the fungal terpenome
inferred← citeshttps://doi.org/10.1039/c6np00059bopenalex-snapshot
Diterpenoids of terrestrial origin
inferred← citeshttps://doi.org/10.1039/c7cs00431aopenalex-snapshot
Secondary metabolism in the lichen symbiosis
inferred← citeshttps://doi.org/10.1039/c7np00027hopenalex-snapshot
Diterpenoids from Isodon species: an update
inferred← citeshttps://doi.org/10.1039/c7ra07060hopenalex-snapshot
New and bioactive natural products from an endophyte of Panax notoginseng
inferred← citeshttps://doi.org/10.1055/s-0041-1730956openalex-snapshot
Synthesis and Antitumor Activity of (3-Hydroxyacrylato-O,O′) Diammineplatinum(II)
inferred← citeshttps://doi.org/10.1073/pnas.1406999111openalex-snapshot
Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases
inferred← citeshttps://doi.org/10.1080/10286020.2015.1135906openalex-snapshot
Three new drimane-type sesquiterpenoids, chaetothyrins A–C, from an endolichenic fungus Chaetothyriales sp.
inferred← citeshttps://doi.org/10.1080/10286020.2025.2501030openalex-snapshot
Endophytic microorganisms in lichen: rising stars in the biomedicine field deserving broader recognition
inferred← citeshttps://doi.org/10.1080/14786419.2016.1190719openalex-snapshot
Activity of compounds from Taxillus sutchuenensis as inhibitors of HCV NS3 serine protease
inferred← citeshttps://doi.org/10.1080/21501203.2017.1352048openalex-snapshot
Endolichenic fungi: the lesser known fungal associates of lichens
inferred← citeshttps://doi.org/10.11005/jbm.2019.26.2.113openalex-snapshot
Extracts ofFlavoparmeliasp. Inhibit Receptor Activator of Nuclear Factor-κB Ligand-Mediated Osteoclast Differentiation
inferred← citeshttps://doi.org/10.1111/1462-2920.70112openalex-snapshot
A Biosynthetic and Taxonomic Atlas of the Global Lichen Holobiont
inferred← citeshttps://doi.org/10.1111/bph.15974openalex-snapshot
The natural product argentatin C attenuates postoperative pain via inhibition of voltage‐gated sodium and T‐type voltage‐gated calcium channels
inferred← citeshttps://doi.org/10.1111/nph.17886openalex-snapshot
Endophytism and endolichenism in Pezizomycetes: the exception or the rule?
inferred← citeshttps://doi.org/10.11606/t.60.2013.tde-27062013-101222openalex-snapshot
Caracterização fitoquímica, avaliação das atividades analgésica e anti-inflamatória e biotransformação de um composto isolado das folhas de Copaifera langsdorffii
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10′-Deoxy-10′ α-hydroxyascochlorin, a New Cell Migration Inhibitor and Other Metabolites from Acremonium sp., a Fungal Endophyte in Ephedra trifurca
inferred← citeshttps://doi.org/10.1177/1934578x1300800802openalex-snapshot
Microbial Biotransformation of 16α,17-Epoxy- Ent -kaurane-19-oic acid by Beauveria Sulfurescens ATCC 7159-F
inferred← citeshttps://doi.org/10.1177/1934578x1501001007openalex-snapshot
Cytotoxic Cytochalasins and Other Metabolites from Xylariaceae sp. FL0390, a Fungal Endophyte of Spanish Moss
inferred← citeshttps://doi.org/10.1186/s13041-020-00616-2openalex-snapshot
1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain
inferred← citeshttps://doi.org/10.1186/s13065-020-00671-9openalex-snapshot
Auto-oxidation of Ent-beyer-15-en-19-al isolated from the essential oil of the heartwood of Erythroxylum monogynum Roxb.: formation of 15,16-epoxy-ent-beyeran-19-oic acid and other products
inferred← citeshttps://doi.org/10.1515/ncrs-2023-0061openalex-snapshot
Crystal structure of 7α,11α-dihydroxy-15-oxo-ent-kauran-16-en-19,6β-olide, C20H26O5
inferred← citeshttps://doi.org/10.1639/007-2745-115.3.465openalex-snapshot
Recent literature on lichens—226
inferred← citeshttps://doi.org/10.2174/0929867322666150821101047openalex-snapshot
Sesterterpenoids with Anticancer Activity
inferred← citeshttps://doi.org/10.2174/1871520619666190118121439openalex-snapshot
Synthesis of Oridonin Derivatives via Mizoroki-Heck Reaction and Click Chemistry for Cytotoxic Activity
inferred← citeshttps://doi.org/10.3389/fchem.2022.885487openalex-snapshot
Novel Triterpenoid Alkaloids With Their Potential Cytotoxic Activity From the Roots of Siraitia grosvenorii
inferred← citeshttps://doi.org/10.3389/fphar.2022.986946openalex-snapshot
An acetonic extract and secondary metabolites from the endolichenic fungus Nemania sp. EL006872 exhibit immune checkpoint inhibitory activity in lung cancer cell
inferred← citeshttps://doi.org/10.3390/ijms17091395openalex-snapshot
Oridonin, a Promising ent-Kaurane Diterpenoid Lead Compound
inferred← citeshttps://doi.org/10.3390/molecules25215058openalex-snapshot
Teratopyrones A–C, Dimeric Naphtho-γ-Pyrones and Other Metabolites from Teratosphaeria sp. AK1128, a Fungal Endophyte of Equisetum arvense
inferred← citeshttps://doi.org/10.5943/ajom/3/1/18openalex-snapshot
The diversity of endolichenic fungi – A review
inferred← citeshttps://doi.org/10.6084/m9.figshare.11984967openalex-snapshot
Additional file 1 of Auto-oxidation of Ent-beyer-15-en-19-al isolated from the essential oil of the heartwood of Erythroxylum monogynum Roxb.: formation of 15,16-epoxy-ent-beyeran-19-oic acid and other products
inferred← citeshttps://doi.org/10.6084/m9.figshare.11984976openalex-snapshot
Additional file 2 of Auto-oxidation of Ent-beyer-15-en-19-al isolated from the essential oil of the heartwood of Erythroxylum monogynum Roxb.: formation of 15,16-epoxy-ent-beyeran-19-oic acid and other products
inferred← citeshttps://doi.org/10.70675/69c906a4z8a84z4595zbe8bz1f87507c0b52openalex-snapshot
Études phytochimiques du lichen Nephroma laevigatum et de ses champignons endolichéniques. Évaluation des activités antiprolifératives et anti-biofilms.
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