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Reversal of Multidrug Resistance by Morning Glory Resin Glycosides in Human Breast Cancer Cells

https://doi.org/10.1021/np200864m

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-3-211-99661-4_2openalex-snapshot

Resin Glycosides from the Morning Glory Family

inferredcites →https://doi.org/10.1007/s00213-006-0437-9openalex-snapshot

Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein

inferredcites →https://doi.org/10.1016/0040-4020(96)00789-2openalex-snapshot

Detailed FAB-mass spectrometry and high resolution NMR investigations of tricolorins A-E, individual oligosaccharides from the resins of Ipomoea tricolor (Convolvulaceae)

inferredcites →https://doi.org/10.1016/j.ejps.2006.03.002openalex-snapshot

Suppression of P-glycoprotein expression by antipsychotics trifluoperazine in adriamycin-resistant L1210 mouse leukemia cells

inferredcites →https://doi.org/10.1016/j.lfs.2004.12.050openalex-snapshot

Reversal of p-glycoprotein-mediated multidrug resistance by CJX1, an amlodipine derivative, in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells

inferredcites →https://doi.org/10.1016/j.phytochem.2008.12.005openalex-snapshot

Bacterial resistance modifying tetrasaccharide agents from Ipomoea murucoides

inferredcites →https://doi.org/10.1016/j.phytochem.2010.06.018openalex-snapshot

Characterization of a xylose containing oligosaccharide, an inhibitor of multidrug resistance in Staphylococcus aureus, from Ipomoea pes-caprae

inferredcites →https://doi.org/10.1016/j.tiv.2009.02.010openalex-snapshot

Gamma-linolenic acid modulates the response of multidrug-resistant K562 leukemic cells to anticancer drugs

inferredcites →https://doi.org/10.1016/j.tiv.2010.07.020openalex-snapshot

Reversal of P-glycoprotein-mediated multidrug resistance in vitro by milbemycin compounds in adriamycin-resistant human breast carcinoma (MCF-7/adr) cells

inferredcites →https://doi.org/10.1016/s0006-291x(88)81321-4openalex-snapshot

Effects of indole alkaloids on multidrug resistance and labeling of P-glycoprotein by a photoaffinity analog of vinblastine

inferredcites →https://doi.org/10.1016/s0040-4020(02)00284-3openalex-snapshot

HPLC Isolation and structural elucidation of diastereomeric niloyl ester tetrasaccharides from Mexican scammony root

inferredcites →https://doi.org/10.1016/s0040-4020(97)00607-8openalex-snapshot

Isolation and structural characterization of new glyclipid ester type dimers from the resin of Ipomoea tricolor (Convolvulaceae)

inferredcites →https://doi.org/10.1016/s0167-4889(01)00175-6openalex-snapshot

Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols

inferredcites →https://doi.org/10.1016/s0304-3835(02)00359-2openalex-snapshot

Reversal of P-glycoprotein mediated multidrug resistance by a newly synthesized 1,4-benzothiazipine derivative, JTV-519

inferredcites →https://doi.org/10.1016/s0889-8588(01)00016-8openalex-snapshot

Monitoring of cellular resistance to cancer chemotherapy

inferredcites →https://doi.org/10.1021/jf801973mopenalex-snapshot

Batatinosides II−VI, Acylated Lipooligosaccharides from the Resin Glycosides of Sweet Potato

inferredcites →https://doi.org/10.1021/jm030951yopenalex-snapshot

Jatrophane Diterpenes as Modulators of Multidrug Resistance. Advances of Structure−Activity Relationships and Discovery of the Potent Lead Pepluanin A

inferredcites →https://doi.org/10.1021/np010295+openalex-snapshot

Modulation of the Multidrug-Resistance Phenotype by New Tropane Alkaloid Aromatic Esters from Erythroxylum p ervillei

inferredcites →https://doi.org/10.1021/np0496340openalex-snapshot

Characterization of Lipophilic Pentasaccharides from Beach Morning Glory (Ipomoea pes-caprae)

inferredcites →https://doi.org/10.1021/np050227dopenalex-snapshot

Polyacylated Oligosaccharides from Medicinal Mexican Morning Glory Species as Antibacterials and Inhibitors of Multidrug Resistance inStaphylococcus aureus

inferredcites →https://doi.org/10.1021/np0504457openalex-snapshot

Resin Glycosides from the Flowers of Ipomoea murucoides

inferredcites →https://doi.org/10.1021/np070040hopenalex-snapshot

Resin Glycosides from Ipomoea pes-caprae

inferredcites →https://doi.org/10.1021/np070093zopenalex-snapshot

Batatins I and II, Ester-Type Dimers of Acylated Pentasaccharides from the Resin Glycosides of Sweet Potato

inferredcites →https://doi.org/10.1021/np0701529openalex-snapshot

Intrapilosins I−VII, Pentasaccharides from the Seeds of Ipomoea intrapilosa

inferredcites →https://doi.org/10.1021/np200080kopenalex-snapshot

Resin Glycosides from the Herbal Drug Jalap (Ipomoea purga)

inferredcites →https://doi.org/10.1021/np800148wopenalex-snapshot

Inhibitors of Bacterial Multidrug Efflux Pumps from the Resin Glycosides of Ipomoea murucoides

inferredcites →https://doi.org/10.1021/np980144fopenalex-snapshot

Antiplasmodial and Cytotoxic Activity of Natural Bisbenzylisoquinoline Alkaloids

inferredcites →https://doi.org/10.1023/a:1008080911522openalex-snapshot

P-glycoprotein structure and evolutionary homologies

inferredcites →https://doi.org/10.1038/nprot.2006.179openalex-snapshot

Sulforhodamine B colorimetric assay for cytotoxicity screening

inferredcites →https://doi.org/10.1081/dmr-120028427openalex-snapshot

Herbal Modulation of P‐Glycoprotein

inferredcites →https://doi.org/10.1093/jnci/81.2.116openalex-snapshot

Expression of Multidrug Resistance Gene in Human Cancers

inferredcites →https://doi.org/10.1093/jnci/82.13.1107openalex-snapshot

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

inferredcites →https://doi.org/10.1124/jpet.102.044412openalex-snapshot

Effects of the Flavonoids Biochanin A, Morin, Phloretin, and Silymarin on P-Glycoprotein-Mediated Transport

inferredcites →https://doi.org/10.1146/annurev.bi.62.070193.002125openalex-snapshot

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

inferredcites →https://doi.org/10.1146/annurev.biochem.71.102301.093055openalex-snapshot

Mammalian ABC Transporters in Health and Disease

inferredcites →https://doi.org/10.1146/annurev.med.53.082901.103929openalex-snapshot

Mechanisms of Cancer Drug Resistance

inferredcites →https://doi.org/10.1248/cpb.40.3163openalex-snapshot

Resin Glycosides. XV. Simonins I-V, Ether-Soluble Resin Glycosides (Jalapins) from the Roots of Ipomoea batatas (cv. Simon).

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Dihydro-furanones from Hyptis species: Chemical correlations and DFT-NMR/ECD calculations for stereochemical assignments

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Glycolipids from Sargassum filipendula, a Natural Alternative for Overcoming ABC Transporter‐Mediated MDR in Cancer

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Chemistry and biological activity of resin glycosides from Convolvulaceae species

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Dereplication of podophyllotoxin and related cytotoxic lignans in Hyptis verticillata by ultra‐high‐performance liquid chromatography tandem mass spectrometry

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Resistance-modifying Activity in Vinblastine-resistant Human Breast Cancer Cells by Oligosaccharides Obtained from Mucilage of Chia Seeds (Salvia hispanica)

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Application of Interrupted Pummerer Reaction Mediated (IPRm) Glycosylation in Natural Product Synthesis

inferred← citeshttps://doi.org/10.1007/s11101-019-09631-1openalex-snapshot

Reversal of multidrug resistance by amphiphilic morning glory resin glycosides in bacterial pathogens and human cancer cells

inferred← citeshttps://doi.org/10.1007/s11418-018-1197-7openalex-snapshot

Four new resin glycosides, murasakimasarins I–IV, from the tuber of Ipomoea batatas

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Identification and characterization of organic and glycosidic acids in crude resin glycoside fraction from Calystegia hederacea

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Identification and characterization of organic and glycosidic acids in the crude resin glycoside fraction from the leaves and stems of Calystegia japonica

inferred← citeshttps://doi.org/10.1007/s11418-024-01787-1openalex-snapshot

Four new resin glycosides from Ipomoea muricata seeds: muricatins XIV–XVII

inferred← citeshttps://doi.org/10.1007/s11418-024-01838-7openalex-snapshot

Eleven new glycosidic acid methyl esters from the crude resin glycoside fraction of Ipomoea alba seeds

inferred← citeshttps://doi.org/10.1007/s11418-024-01868-1openalex-snapshot

Ten new resin glycosides, ipoalbins I–X, from Ipomoea alba seeds

inferred← citeshttps://doi.org/10.1007/s11418-025-01877-8openalex-snapshot

Four new acylated glycosidic acid methyl esters and a new glycosidic acid from Ipomoea lacunosa seeds

inferred← citeshttps://doi.org/10.1007/s11418-025-01919-1openalex-snapshot

Eight new resin glycosides, calyhedins XXIV–XXXI, from the rhizomes of Calystegia hederacea

inferred← citeshttps://doi.org/10.1007/s43450-022-00332-zopenalex-snapshot

Amarisolide H and 15-epi-Amarisolide H, Two Diterpenoid Glucosides from Salvia circinnata

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Chemosensitizing Glycolipids from Ipomoea murucoides: Affinity-Directed Fractionation Using G6Pase, In Vitro Evaluation in MDR Cells, and In Silico Analysis in P-gp

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Total Synthesis of Ipomoeassin F and Its Analogs for Biomedical Research

inferred← citeshttps://doi.org/10.1016/j.bjp.2017.05.003openalex-snapshot

HPLC-MS profiling of the multidrug-resistance modifying resin glycoside content of Ipomoea alba seeds

inferred← citeshttps://doi.org/10.1016/j.bmcl.2014.12.083openalex-snapshot

Multidrug resistance–reversal effects of resin glycosides from Dichondra repens

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Isolation and structural characterization of eight new resin glycosides, calyhedins XVI–XXIII, from the rhizomes of Calystegia hederacea

inferred← citeshttps://doi.org/10.1016/j.carres.2024.109048openalex-snapshot

Identification and characterization of organic and glycosidic acids in the crude resin glycoside fraction of Ipomoea lacunosa seeds

inferred← citeshttps://doi.org/10.1016/j.carres.2024.109142openalex-snapshot

Identification and characterization of organic and glycosidic acids in the crude resin glycoside fraction of Ipomoea alba seeds

inferred← citeshttps://doi.org/10.1016/j.carres.2026.109845openalex-snapshot

Seven new resin glycosides, ipoalbins XXII–XXVIII, from the seeds of Ipomoea alba

inferred← citeshttps://doi.org/10.1016/j.ejmech.2016.05.045openalex-snapshot

neo-Clerodane diterpenoids from Scutellaria barbata mediated inhibition of P-glycoprotein in MCF-7/ADR cells

inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.10.015openalex-snapshot

Amphiphilic glycoconjugates as potential anti-cancer chemotherapeutics

inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.01.027openalex-snapshot

Jatrophane diterpenoids from Euphorbia sororia as potent modulators against P-glycoprotein-based multidrug resistance

inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114300openalex-snapshot

Development of oxoisoaporphine derivatives with topoisomerase I inhibition and reversal of multidrug resistance in breast cancer MCF-7/ADR cells

inferred← citeshttps://doi.org/10.1016/j.fitote.2016.08.007openalex-snapshot

Structural elucidation and evaluation of multidrug-resistance modulatory capability of amarissinins A–C, diterpenes derived from Salvia amarissima

inferred← citeshttps://doi.org/10.1016/j.fitote.2025.106787openalex-snapshot

Eleven new resin glycosides, ipoalbins XI–XXI, from Ipomoea alba seeds

inferred← citeshttps://doi.org/10.1016/j.jconrel.2021.06.034openalex-snapshot

Nanoplatform-based natural products co-delivery system to surmount cancer multidrug-resistant

inferred← citeshttps://doi.org/10.1016/j.jep.2020.113198openalex-snapshot

Traditional uses, ten-years research progress on phytochemistry and pharmacology, and clinical studies of the genus Scutellaria

inferred← citeshttps://doi.org/10.1016/j.jep.2024.119316openalex-snapshot

The jalap roots: A herbal legacy from the neotropics to the world

inferred← citeshttps://doi.org/10.1016/j.molstruc.2019.127409openalex-snapshot

NMR and SC-XRD analyses of a solid solution of diastereomers of microphyllane diterpenoids from Salvia hirsuta

inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.139132openalex-snapshot

Amarissinin F and its 16-epimer, two neo-clerodane diterpenoids from Salvia amarissima containing a 5-hydroxy-furan-2(5H)-one with MDR modulatory activity in cancer cells

inferred← citeshttps://doi.org/10.1016/j.phyplu.2022.100359openalex-snapshot

Isolation and in vivo evaluation of anti-breast cancer activity of resin glycoside merremoside from Ipomoea aquatica Forsskal in overcoming multi-drug resistance

inferred← citeshttps://doi.org/10.1016/j.phytochem.2012.05.010openalex-snapshot

Resin glycosides from the aerial parts of Operculina turpethum

inferred← citeshttps://doi.org/10.1016/j.phytochem.2012.11.011openalex-snapshot

Sesquiterpene lactones from the extracts of two Balkan endemic Laserpitium species and their cytotoxic activity

inferred← citeshttps://doi.org/10.1016/j.phytochem.2013.07.007openalex-snapshot

Modulators of antibiotic activity from Ipomoea murucoides

inferred← citeshttps://doi.org/10.1016/j.phytochem.2016.01.004openalex-snapshot

Resin glycosides from Ipomoea wolcottiana as modulators of the multidrug resistance phenotype in vitro

inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.01.012openalex-snapshot

Morning glory resin glycosides as α-glucosidase inhibitors: In vitro and in silico analysis

inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.01.020openalex-snapshot

Resin glycosides from the seeds of Ipomoea muricata and their multidrug resistance reversal activities

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Calyhedins I–VI: Resin glycosides from the rhizomes of Calystegia hederacea

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Hederifolic acids A-D, hepta and hexasaccharides from the resin glycosides of Ipomoea hederifolia

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Inhibition of multidrug-resistant MCF-7 breast cancer cells with combinations of clinical drugs and resin glycosides from Operculina hamiltonii

inferred← citeshttps://doi.org/10.1016/j.phytol.2016.07.022openalex-snapshot

Jalapinoside II, a bisdesmoside resin glycoside, and related glycosidic acids from the officinal jalap root ( Ipomoea purga )

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Acylsugar diversity in the resin glycosides from Ipomoea tricolor seeds as chemosensitizers in breast cancer cells

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Neo-clerodane diterpenoids from Scutellaria barbata and their reversal multidrug resistance activity in HepG2/Adr cells

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Unusual ether-type resin glycoside dimers from the seeds of Cuscuta chinensis

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Pharesinosides A-G, acylated glycosidic acid methyl esters derivatized by NH 2 silica gel on-column catalyzation from the crude resin glycosides of Pharbitis Semen

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Phytochemical Investigation of the Roots of Ipomoea asarifolia and Antiproliferative Activity of the Isolated Compounds against Multiple Myeloma Cells

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c00594openalex-snapshot

Resin Glycosides from Operculina hamiltonii and Their Synergism with Vinblastine in Cancer Cells

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Resin Glycosides from Ipomoea funis as Inhibitors of P-Glycoprotein in Multidrug-Resistant Breast Carcinoma Cells

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b00782openalex-snapshot

Resin Glycosides from Ipomoea alba Seeds as Potential Chemosensitizers in Breast Carcinoma Cells

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Complementarity of DFT Calculations, NMR Anisotropy, and ECD for the Configurational Analysis of Brevipolides K–O from Hyptis brevipes

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.8b00507openalex-snapshot

Jatrophane Diterpenoids from Euphorbia glomerulans

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.8b00565openalex-snapshot

Amarisolide F, an Acylated Diterpenoid Glucoside and Related Terpenoids from Salvia amarissima

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.8b00860openalex-snapshot

Parvifoline Derivatives as Tubulin Polymerization Inhibitors

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.8b00908openalex-snapshot

Structure Elucidation, Conformation, and Configuration of Cytotoxic 6-Heptyl-5,6-dihydro-2H-pyran-2-ones from Hyptis Species and Their Molecular Docking to α-Tubulin

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Ipomeolides A and B, Resin Glycosides from Ipomoea pes-caprae and Combination Therapy of Ipomeolide A with Doxorubicin

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.9b00056openalex-snapshot

Glycosidic Acids with Unusual Aglycone Units from Convolvulus arvensis

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.9b00222openalex-snapshot

Resin Glycosides from the Roots of Operculina macrocarpa (Brazilian Jalap) with Purgative Activity

inferred← citeshttps://doi.org/10.1021/acs.orglett.5b01320openalex-snapshot

Teotihuacanin, a Diterpene with an Unusual Spiro-10/6 System from Salvia amarissima with Potent Modulatory Activity of Multidrug Resistance in Cancer Cells

inferred← citeshttps://doi.org/10.1021/acs.orglett.9b02004openalex-snapshot

Total Syntheses of Resin Glycosides Murucoidins IV and V

inferred← citeshttps://doi.org/10.1021/jf402952dopenalex-snapshot

Resin Glycosides from the Yellow-Skinned Variety of Sweet Potato (Ipomoea batatas)

inferred← citeshttps://doi.org/10.1021/np300414dopenalex-snapshot

Mammalian Multidrug Resistance Lipopentasaccharide Inhibitors from Ipomoea alba Seeds

inferred← citeshttps://doi.org/10.1021/np300739yopenalex-snapshot

Purgin II, a Resin Glycoside Ester-Type Dimer and Inhibitor of Multidrug Efflux Pumps from Ipomoea purga

inferred← citeshttps://doi.org/10.1021/np300740hopenalex-snapshot

Absolute Configuration and Conformational Analysis of Brevipolides, Bioactive 5,6-Dihydro-α-pyrones from Hyptis brevipes

inferred← citeshttps://doi.org/10.1021/np500483dopenalex-snapshot

Merremins A–G, Resin Glycosides from Merremia hederacea with Multidrug Resistance Reversal Activity

inferred← citeshttps://doi.org/10.1021/np500523wopenalex-snapshot

Batatins VIII–XI, Glycolipid Ester-Type Dimers from Ipomoea batatas

inferred← citeshttps://doi.org/10.1021/np5005246openalex-snapshot

Cytotoxic Resin Glycosides from Ipomoea aquatica and Their Effects on Intracellular Ca2+ Concentrations

inferred← citeshttps://doi.org/10.1021/np500762wopenalex-snapshot

Jalapinoside, a Macrocyclic Bisdesmoside from the Resin Glycosides of Ipomea purga, as a Modulator of Multidrug Resistance in Human Cancer Cells

inferred← citeshttps://doi.org/10.1039/c7np00050bopenalex-snapshot

Constrained saccharides: a review of structure, biology, and synthesis

inferred← citeshttps://doi.org/10.1039/c7ra09026aopenalex-snapshot

Pentasaccharide resin glycosides with multidrug resistance reversal activities from the seeds of Pharbitis nil

inferred← citeshttps://doi.org/10.1080/14786419.2017.1280492openalex-snapshot

A new resin glycoside from Calystegia soldanella and its antiviral activity towards herpes

inferred← citeshttps://doi.org/10.1080/14786419.2020.1761362openalex-snapshot

Two new glycosidic acids, calyhedic acids E and F, in crude resin glycoside fraction from Calystegia hederacea

inferred← citeshttps://doi.org/10.1080/14786419.2022.2125970openalex-snapshot

Two new resin glycosides, muricatins XII and XIII, from the seeds of Ipomoea muricata

inferred← citeshttps://doi.org/10.1080/23802359.2024.2336703openalex-snapshot

The complete chloroplast genome sequence of Calystegia hederacea Wall. in Roxb. 1824 (Convolvulaceae) in Enshi, Hubei

inferred← citeshttps://doi.org/10.1089/jmf.2017.0124openalex-snapshot

Phytochemical Profile, Toxicity, and Pharmacological Potential of Peels from Four Species of Tropical Fruits

inferred← citeshttps://doi.org/10.1248/cpb.c25-00244openalex-snapshot

Resin Glycosides from the Leaves and Stems of Ipomoea lacunosa

inferred← citeshttps://doi.org/10.1248/cpb.c25-00523openalex-snapshot

Three New Acylated Glycosidic Acid Methyl Esters from the Crude Resin Glycoside Fraction of Ipomoea lacunosa Seeds by Treatment with Indium(III) Chloride in Methanol

inferred← citeshttps://doi.org/10.2139/ssrn.5339296openalex-snapshot

Resin Glycosides from Ipomoea Funis as Inhibitors of P-Glycoprotein for Overcoming Multidrug Resistance in Cancer Therapy

inferred← citeshttps://doi.org/10.21873/anticanres.15437openalex-snapshot

Sensitization Effects of Repurposed Blood Pressure-regulating Drugs on Drug-resistant Cancer Cells

inferred← citeshttps://doi.org/10.21873/invivo.12599openalex-snapshot

Drug Repositioning With an Anticancer Effect: Contributions to Reduced Cancer Incidence in Susceptible Individuals

inferred← citeshttps://doi.org/10.31557/apjcp.2022.23.11.3657openalex-snapshot

Evaluation of the Role of Merromoside from Ipomoea aquatica Forsskal Hydroalcoholic Extract in the Downregulation of ROS Species in Overcoming MDR in Breast Cancer

inferred← citeshttps://doi.org/10.3389/fchem.2022.1036954openalex-snapshot

Progress in the total synthesis of resin glycosides

inferred← citeshttps://doi.org/10.3389/fnut.2026.1783378openalex-snapshot

UHPLC-Q-TOF-MS/MS profiling of resin glycosides and their lipase inhibitory activity in leaves of selected sweet potato (Ipomoea batatas L.) cultivars

inferred← citeshttps://doi.org/10.3389/fphar.2019.00783openalex-snapshot

Selective Acetogenins and Their Potential as Anticancer Agents

inferred← citeshttps://doi.org/10.3390/app12125818openalex-snapshot

In Vitro Assessment of Antiproliferative Activity and Cytotoxicity Modulation of Capsicum chinense By-Product Extracts

inferred← citeshttps://doi.org/10.3390/futurepharmacol5010005openalex-snapshot

An Overview of Sargassum Seaweed as Natural Anticancer Therapy

inferred← citeshttps://doi.org/10.3390/molecules19045421openalex-snapshot

Conformational Characterization of Ipomotaosides and Their Recognition by COX-1 and 2

inferred← citeshttps://doi.org/10.3390/molecules190913848openalex-snapshot

Tyrosine Kinase Inhibitors as Reversal Agents for ABC Transporter Mediated Drug Resistance

inferred← citeshttps://doi.org/10.3390/molecules27113638openalex-snapshot

Mass Defect Filtering-Oriented Identification of Resin Glycosides from Root of Convolvulus scammonia Based on Quadrupole-Orbitrap Mass Spectrometer

inferred← citeshttps://doi.org/10.58837/chula.cmj.63.3.2openalex-snapshot

Cytotoxicity and apoptotic mechanisms of different solvent extracts from Ipomoea pes-caprae on human nasopharyngeal cells

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