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Jatrophane Diterpenes as Modulators of Multidrug Resistance. Advances of Structure−Activity Relationships and Discovery of the Potent Lead Pepluanin A

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/bf00234655openalex-snapshot
The biology of the P-glycoproteins
inferredcites →https://doi.org/10.1007/s002329900305openalex-snapshot
The P-Glycoprotein Efflux Pump: How Does it Transport Drugs?
inferredcites →https://doi.org/10.1016/s0168-6445(97)00051-xopenalex-snapshot
Mechanisms of multidrug transporters
inferredcites →https://doi.org/10.1016/s0960-9822(00)00059-2openalex-snapshot
P-Glycoprotein: To flip or not to flip?
inferredcites →https://doi.org/10.1021/jm0111301openalex-snapshot
Discovery and Biological Evaluation of a New Family of Potent Modulators of Multidrug Resistance: Reversal of Multidrug Resistance of Mouse Lymphoma Cells by New Natural Jatrophane Diterpenoids Isolated from Euphorbia Species
inferredcites →https://doi.org/10.1021/jm030787eopenalex-snapshot
Jatrophane Diterpenes as P-Glycoprotein Inhibitors. First Insights of Structure−Activity Relationships and Discovery of a New, Powerful Lead
inferredcites →https://doi.org/10.1021/jm991128yopenalex-snapshot
C-Isoprenylation of Flavonoids Enhances Binding Affinity toward P-Glycoprotein and Modulation of Cancer Cell Chemoresistance
inferredcites →https://doi.org/10.1021/np970507wopenalex-snapshot
Macrocyclic Diterpenoids from Euphorbia semiperfoliata
inferredcites →https://doi.org/10.1124/mol.51.6.1024openalex-snapshot
P-Glycoprotein Substrates and Antagonists Cluster into Two Distinct Groups

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Jatrophane Diterpenes as Modulators of Multidrug Resistance. Advances of Structure—Activity Relationships and Discovery of the Potent Lead Pepluanin A.
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Diterpenes from European Euphorbia Species Serving as Prototypes for Natural‐Product‐Based Drug Discovery
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Euphoresulanes A–M, structurally diverse jatrophane diterpenoids from Euphorbia esula
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Diterpenoids from Euphorbia peplus possessing cytotoxic and anti-inflammatory activities
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Structure–activity relationship of natural and synthetic coumarins inhibiting the multidrug transporter P-glycoprotein
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Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids
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Synergistic interaction between p-glycoprotein modulators and epirubicine on resistant cancer cells
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Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures
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Paraliane and pepluane diterpenes as anti-inflammatory agents: First insights in structure–activity relationships
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Jatrophane diterpenoids from Euphorbia sororia as potent modulators against P-glycoprotein-based multidrug resistance
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Discovery of a novel highly potent and low-toxic jatrophane derivative enhancing the P-glycoprotein-mediated doxorubicin sensitivity of MCF-7/ADR cells
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Selective modulation of P-glycoprotein activity by steroidal saponines from Paris polyphylla
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Macrocyclic diterpenoids from the Iranian plant Euphorbia bungei Boiss.
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A new cytotoxic cembrane diterpene from the roots of Euphorbia pekinensis Rupr
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Jatrophane diterpenoid esters from Euphorbia sororia serving as multidrug resistance reversal agents
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Cyparissins A and B, jatrophane diterpenes from Euphorbia cyparissias as Pgp inhibitors and cytotoxic agents against ovarian cancer cell lines
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Jatrophanes as promising multidrug resistance modulators: Advances of structure–activity relationships
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Complementary and alternative medicine use among cancer patients in Palestine with special reference to safety-related concerns
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A myrsinol diterpene isolated from a traditional herbal medicine, LANGDU reverses multidrug resistance in breast cancer cells
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Oxazolidinones as chiral auxiliaries in asymmetric aldol reaction applied to natural products total synthesis
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Phytochemical profile of Euphorbia peplus L. collected in Central Italy and NMR semi-quantitative analysis of the diterpenoid fraction
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New malonate macrocycle bearing two isosteviol moieties and its adduct with fullerene C60
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NMR and SC-XRD analyses of a solid solution of diastereomers of microphyllane diterpenoids from Salvia hirsuta
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Anticancer diterpenes of African natural products: Mechanistic pathways and preclinical developments
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Multidrug resistance reversal agent from Jatropha elliptica
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Chemical profile and defensive function of the latex of Euphorbia peplus
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Jatrophane diterpenoids from Fructus Euphorbia sororia
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Three new jatrophane diterpenoids from Euphorbia peplus Linn. with activity towards autophagic flux
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Biodiversity characteristics of Teucrium polium species in Saudi Arabia
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Amygdaloidins A–L, twelve new 13 α-OH jatrophane diterpenes from Euphorbia amygdaloides L.
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A New Jatrophane Diterpenoid from Euphorbia peplus
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Lathyrol Diterpenes as Modulators of P-Glycoprotein Dependent Multidrug Resistance: Structure–Activity Relationship Studies on Euphorbia Factor L 3 Derivatives
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Original Vinca Derivatives: From P-Glycoprotein Substrates to P-Glycoprotein Inhibitors
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Jatrophane Diterpenoids as Modulators of P-Glycoprotein-Dependent Multidrug Resistance (MDR): Advances of Structure–Activity Relationships and Discovery of Promising MDR Reversal Agents
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Jatrophane Diterpenoids from Euphorbia peplus as Multidrug Resistance Modulators with Inhibitory Effects on the ATR-Chk-1 Pathway
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Pepluane and Paraliane Diterpenoids from Euphorbia peplus with Potential Anti-inflammatory Activity
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Evaluation of Jatrophane Esters from Euphorbia spp. as Modulators of Candida albicans Multidrug Transporters
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Environmentally Friendly Procedure Based on Supercritical Fluid Chromatography and Tandem Mass Spectrometry Molecular Networking for the Discovery of Potent Antiviral Compounds from Euphorbia semiperfoliata
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Jatrophane Diterpenoids from Euphorbia glomerulans
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One-Step Semisynthesis of a Segetane Diterpenoid from a Jatrophane Precursor via a Diels–Alder Reaction
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Pepluanols C–D, Two Diterpenoids with Two Skeletons from Euphorbia peplus
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Chemical and Pharmacological Research of the Plants in Genus Euphorbia
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Discovery and Biological Evaluation of the Novel Naturally Occurring Diterpene Pepluanone as Antiinflammatory Agent
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Nonprenylated Rotenoids, a New Class of Potent Breast Cancer Resistance Protein Inhibitors
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Synthetic Studies toward Jatrophane Diterpenes from Euphorbia characias. Enantioselective Synthesis of (−)-15-O-Acetyl-3-O-propionyl-17-norcharaciol
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Reversal of Multidrug Resistance by Morning Glory Resin Glycosides in Human Breast Cancer Cells
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Jatrophane Diterpenes fromEuphorbia melliferaand Their Activity as P-Glycoprotein Modulators on Multidrug-Resistant Mouse Lymphoma and Human Colon Adenocarcinoma Cells
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Jatrophanes from Euphorbia squamosa as Potent Inhibitors of Candida albicans Multidrug Transporters
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Synthesis of the Norjatrophane Diterpene (−)-15-Acetyl-3-propionyl- 17-norcharaciol
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Biogenetical Related Highly Oxygenated Macrocyclic Diterpenes from Sea Spurge Euphorbia paralias
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Total Synthesis of Jatrophane Diterpenes from Euphorbia characias
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Diterpenoids
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Polyphenols from Euphorbia pekinensis Inhibit AGEs Formation In Vitro and Vessel Dilation in Larval Zebrafish In Vivo
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Three New Jatrophane Polyesters and Antiproliferative Constituents from Euphorbia tuckeyana
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Metabolomic evaluation of Euphorbia pekinensis induced nephrotoxicity in rats
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Roles of Lamiaceae plants from the arid and desert rangelands of Tunisia in human health and therapy
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Bacterial efflux pump inhibitors from natural sources
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Plant Compounds and Derivatives as Inhibitors of Cancer Cell Multidrug Resistance
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Dihidro-β-Agarofuran Sesquiterpenes: A New Class of Reversal Agents of the Multidrug Resistance Phenotype Mediated by P-Glycoprotein in the Protozoan Parasite Leishmania
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Inhibition of Multidrug Resistance of Cancer Cells by Natural Diterpenes, Triterpenes and Carotenoids
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Phytochemical Investigation of a Native North American Species, “Acer saccarinum” and an Endemic Saudi Arabian Species, “Euphorbia saudiarabica”
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In vitro and in vivo assessment of CYP2C9-mediated herb–herb interaction of Euphorbiae Pekinensis Radix and Glycyrrhizae Radix
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Research Progress on Natural Diterpenoids in Reversing Multidrug Resistance
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Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology
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Macrocyclic Diterpenoids from Euphorbia peplus Possessing Activity Towards Autophagic Flux
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Jatrophane Diterpenoids from Euphorbia peplus with LysoTracker-Associated Cellular Activity
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A New Jatrophane Diterpenoid from Euphorbia peplus
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