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Potent Cytotoxic Arylnaphthalene Lignan Lactones from Phyllanthus poilanei

https://doi.org/10.1021/np5002785
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ardp.201200035openalex-snapshot
Synthesis and Bioevaluation of Diphyllin Glycosides as Novel Anticancer Agents
inferredcites →https://doi.org/10.1002/hlca.200690033openalex-snapshot
A New Lignan and Four New Lignan Glycosides from Mananthes patentiflora
inferredcites →https://doi.org/10.1002/pca.1286openalex-snapshot
Rapid screening of lignans from Phyllanthus myrtifolius and stilbenoids from Syagrus romanzoffiana by HPLC‐SPE‐NMR
inferredcites →https://doi.org/10.1007/978-1-62703-122-6_20openalex-snapshot
Use of the Hollow Fiber Assay for the Discovery of Novel Anticancer Agents from Fungi
inferredcites →https://doi.org/10.1007/s10495-009-0440-9openalex-snapshot
Cellular responses to etoposide: cell death despite cell cycle arrest and repair of DNA damage
inferredcites →https://doi.org/10.1016/0031-9422(95)00195-dopenalex-snapshot
Antifungal aryltetralin lignans from leaves of Podophyllum hexandrum
inferredcites →https://doi.org/10.1016/0031-9422(96)00061-1openalex-snapshot
Minor lignans from haplophyllum cappadocicum
inferredcites →https://doi.org/10.1016/0147-619x(83)90019-7openalex-snapshot
Determination of plasmid copy number by fluorescence densitometry
inferredcites →https://doi.org/10.1016/j.carres.2004.05.023openalex-snapshot
The gel-forming polysaccharide of psyllium husk (Plantago ovata Forsk)
inferredcites →https://doi.org/10.1016/j.ejmech.2011.11.011openalex-snapshot
Design, synthesis and biological evaluation of novel glycosylated diphyllin derivatives as topoisomerase II inhibitors
inferredcites →https://doi.org/10.1016/j.fitote.2009.05.005openalex-snapshot
A new arylnaphthalene lignan from Knema furfuracea
inferredcites →https://doi.org/10.1016/j.immuni.2006.03.016openalex-snapshot
Pro- and Antiinflammatory Cytokine Signaling: Reciprocal Antagonism Regulates Interferon-gamma Production by Human Natural Killer Cells
inferredcites →https://doi.org/10.1016/j.phytochem.2009.05.016openalex-snapshot
Glycosides of arylnaphthalene lignans from Acanthus mollis having axial chirality
inferredcites →https://doi.org/10.1016/s0031-9422(98)00222-2openalex-snapshot
A arylnaphthalene lignan from Haplophyllum buxbaumii
inferredcites →https://doi.org/10.1016/s0040-4020(01)93074-1openalex-snapshot
The isolation and structure of three new lignans from Justicia procumbens Linn. var. leucantha honda
inferredcites →https://doi.org/10.1016/s0092-8674(04)00031-5openalex-snapshot
Mitochondrial activation of apoptosis
inferredcites →https://doi.org/10.1021/jo952048eopenalex-snapshot
Hindered Rotation in Arylnaphthalene Lignans
inferredcites →https://doi.org/10.1021/jo971176vopenalex-snapshot
NMR Chemical Shifts of Common Laboratory Solvents as Trace Impurities
inferredcites →https://doi.org/10.1021/ml300065zopenalex-snapshot
Synthesis and Antitumor Activity of Ellagic Acid Peracetate
inferredcites →https://doi.org/10.1021/np0101651openalex-snapshot
Potent Cytotoxic Lignans from Justicia procumbens and Their Effects on Nitric Oxide and Tumor Necrosis Factor-α Production in Mouse Macrophages
inferredcites →https://doi.org/10.1021/np050028uopenalex-snapshot
Cytotoxic Arylnaphthalene Lignans from a Vietnamese Acanthaceae, Justicia patentiflora
inferredcites →https://doi.org/10.1021/np060022kopenalex-snapshot
Production of Justicidin B, a Cytotoxic Arylnaphthalene Lignan from Genetically Transformed Root Cultures of Linum l eonii
inferredcites →https://doi.org/10.1021/np200051jopenalex-snapshot
Cytotoxic and NF-κB Inhibitory Constituents of the Stems of Cratoxylum cochinchinense and Their Semisynthetic Analogues
inferredcites →https://doi.org/10.1021/np200906sopenalex-snapshot
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
inferredcites →https://doi.org/10.1021/np3007414openalex-snapshot
Alkaloids from Microcos paniculata with Cytotoxic and Nicotinic Receptor Antagonistic Activities
inferredcites →https://doi.org/10.1021/np50044a030openalex-snapshot
Antitumor Agents, 81. Justicidin-A and Diphyllin, Two Cytotoxic Principles from Justicia procumbens
inferredcites →https://doi.org/10.1021/np50071a003openalex-snapshot
Chemical Constituents of the Flora of Jordan, Part V-B. Three New Arylnaphthalene Lignan Glucosides from Haplophyllum buxbaumii
inferredcites →https://doi.org/10.1021/np50100a011openalex-snapshot
Cytotoxic Constituents from Hyptis verticillata
inferredcites →https://doi.org/10.1021/np50116a013openalex-snapshot
Phyllamyricins A-C, Three Novel Lignans from Phyllanthus myrtifolius
inferredcites →https://doi.org/10.1021/np7007347openalex-snapshot
Dichapetalin-Type Triterpenoids and Lignans from the Aerial Parts of Phyllanthus acutissima
inferredcites →https://doi.org/10.1021/np800767aopenalex-snapshot
Use of the in Vivo Hollow Fiber Assay in Natural Products Anticancer Drug Discovery
inferredcites →https://doi.org/10.1021/np9900167openalex-snapshot
Cytotoxic Lignans of Justicia ciliata
inferredcites →https://doi.org/10.1023/a:1008138230896openalex-snapshot
Production of podophyllotoxin from Podophyllum hexandrum: a potential natural product for clinically useful anticancer drugs
inferredcites →https://doi.org/10.1038/sj.onc.1204402openalex-snapshot
Defective caspase-3 relocalization in non-small cell lung carcinoma
inferredcites →https://doi.org/10.1055/s-2003-39706openalex-snapshot
Antifungal, Antiprotozoal, Cytotoxic and Piscicidal Properties of Justicidin B and a New Arylnaphthalide Lignan fromPhyllanthus piscatorum
inferredcites →https://doi.org/10.1055/s-2005-873141openalex-snapshot
Cytotoxic Arylnaphthalide Lignan Glycosides from the Aerial Parts of Phyllanthus taxodiifolius
inferredcites →https://doi.org/10.1080/1057563031000122095openalex-snapshot
Cytotoxicity ofin vitroproduced podophyllotoxin frompodophyllum hexandrumon human cancer cell line
inferredcites →https://doi.org/10.1093/mutage/11.6.553openalex-snapshot
Cytotoxic and genotoxic effects of cleistanthin B in normal and tumour cells
inferredcites →https://doi.org/10.1101/gad.12.6.806openalex-snapshot
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
inferredcites →https://doi.org/10.1107/s002188980403225xopenalex-snapshot
SIR2004: an improved tool for crystal structure determination and refinement
inferredcites →https://doi.org/10.1107/s0021889899006020openalex-snapshot
WinGX suite for small-molecule single-crystal crystallography
inferredcites →https://doi.org/10.1107/s0108767307043930openalex-snapshot
A short history of SHELX
inferredcites →https://doi.org/10.1124/mol.104.004416openalex-snapshot
Biochemical and Proteomics Approaches to Characterize Topoisomerase IIα Cysteines and DNA as Targets Responsible for Cisplatin-Induced Inhibition of Topoisomerase IIα
inferredcites →https://doi.org/10.1196/annals.1397.047openalex-snapshot
Resveratrol Induces Apoptosis in Chemoresistant Cancer Cells via Modulation of AMPK Signaling Pathway
inferredcites →https://doi.org/10.1248/cpb.50.844openalex-snapshot
Patavine, a New Arylnaphthalene Lignan Glycoside from Shoot Cultures of Haplophyllum patavinum.
inferredcites →https://doi.org/10.1248/cpb.51.1299openalex-snapshot
Arylnaphthalide Lignans from Cleistanthus collinus
inferredcites →https://doi.org/10.1248/cpb.54.1223openalex-snapshot
Cytotoxic Arylnaphthalene Lignans from Phyllanthus oligospermus
inferredcites →https://doi.org/10.1351/pac-con-08-10-16openalex-snapshot
Discovery of anticancer agents of diverse natural origin
inferredcites →https://doi.org/10.1593/neo.11972openalex-snapshot
A Novel Topoisomerase Inhibitor, Daurinol, Suppresses Growth of HCT116 Cells with Low Hematological Toxicity Compared to Etoposide
inferredcites →https://doi.org/10.2174/0929867043364531openalex-snapshot
Etoposide: Discovery and Medicinal Chemistry
inferredcites →https://doi.org/10.3390/ijerph9072444openalex-snapshot
Secondary Leukemia Associated with the Anti-Cancer Agent, Etoposide, a Topoisomerase II Inhibitor

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.3897/pharmacia.71.e117690zenodo-depositor-declared
Arylnaphthalene lignans with a focus Linum species: a review on phytochemical, biotechnological and pharmacological potential
inferred← citeshttps://doi.org/10.1002/asia.202301013openalex-snapshot
An Open‐Air Palladium‐Catalyzed Stereoselective O‐Glycosylation of Glycals via in‐situ Generation of gem‐Disubstituted Methanols from p‐Quinone Methides
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Recent Advances in Palladium‐Catalyzed Functionalization of Carbohydrate Frameworks
inferred← citeshttps://doi.org/10.1002/cbdv.202402071openalex-snapshot
Isolation of Novel Compounds from Lepidium sativum Seeds and Evaluation of Their Potential Anti‐Tumor Activity
inferred← citeshttps://doi.org/10.1002/ejoc.201700556openalex-snapshot
First Total Synthesis of the Bioactive Arylnaphthyl Lignan 4‐O‐Glycosides Phyllanthusmin D and 4′′‐O‐Acetylmananthoside B
inferred← citeshttps://doi.org/10.1007/978-3-030-81404-5_15-1openalex-snapshot
Lignans
inferred← citeshttps://doi.org/10.1007/978-3-031-28109-9_15openalex-snapshot
Lignans
inferred← citeshttps://doi.org/10.1007/978-3-319-93506-5_1openalex-snapshot
The Search for Anticancer Agents from Tropical Plants
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Current Status and Future Prospects of Bioactive Phytolignans
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Update on naturally occurring novel arylnaphthalenes from plants
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Arylnaphthalene lactones: structures and pharmacological potentials
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Bioactivity-Guided Isolation of Totarane-Derived Diterpenes from Podocarpus neriifolius and Structure Revision of 3-Deoxy-2α-hydroxynagilactone E
inferred← citeshttps://doi.org/10.1016/b978-0-12-802104-0.00012-3openalex-snapshot
Other Plant Metabolites
inferred← citeshttps://doi.org/10.1016/b978-0-12-816675-8.00003-8openalex-snapshot
Bioactive C-glycosides inspired from natural products towards therapeutics
inferred← citeshttps://doi.org/10.1016/b978-0-443-15269-6.00013-4openalex-snapshot
Semisynthesis of lignans
inferred← citeshttps://doi.org/10.1016/b978-0-443-18657-8.00014-1openalex-snapshot
Other plant metabolites
inferred← citeshttps://doi.org/10.1016/j.bioelechem.2022.108133openalex-snapshot
A c-MWCNTs/AuNPs-based electrochemical cytosensor to evaluate the anticancer activity of pinoresinol from Cinnamomum camphora against HeLa cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.108645openalex-snapshot
Phyllanthus taxodiifolius Beille suppresses microtubule dynamics and restricts glioblastoma aggressiveness
inferred← citeshttps://doi.org/10.1016/j.bmc.2018.03.033openalex-snapshot
Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones
inferred← citeshttps://doi.org/10.1016/j.bmc.2023.117486openalex-snapshot
The mechanisms of multidrug resistance of breast cancer and research progress on related reversal agents
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Antitumor and immunomodulatory activities of diphyllin and its derivatives
inferred← citeshttps://doi.org/10.1016/j.bse.2024.104901openalex-snapshot
Cytotoxicity of endemic Haplophyllum megalanthum Bornm. and its newly isolated alkaloids and lignans
inferred← citeshttps://doi.org/10.1016/j.bse.2026.105357openalex-snapshot
Chemical constituents from the root extract of Phyllanthus reticulatus and their chemotaxonomic significance
inferred← citeshttps://doi.org/10.1016/j.chempr.2018.11.007openalex-snapshot
Site-Selective C–H Functionalization of (Hetero)Arenes via Transient, Non-symmetric Iodanes
inferred← citeshttps://doi.org/10.1016/j.fitote.2018.05.006openalex-snapshot
Phenylacetylene-bearing 3,4-seco-cleistanthane diterpenoids from the roots of Phyllanthus glaucus
inferred← citeshttps://doi.org/10.1016/j.fitote.2019.104198openalex-snapshot
Synthesis, cytotoxicity and anti-invasion activity of three natural diphyllin L-arabinopyranosides
inferred← citeshttps://doi.org/10.1016/j.indcrop.2026.124204openalex-snapshot
Spatiotemporal dynamics and a proposed biosynthetic framework for multi-bioactive arylnaphthalene lignans in Taiwania flousiana Gaussen
inferred← citeshttps://doi.org/10.1016/j.phytochem.2014.12.014openalex-snapshot
Cytotoxic and natural killer cell stimulatory constituents of Phyllanthus songboiensis
inferred← citeshttps://doi.org/10.1016/j.phytochem.2017.01.005openalex-snapshot
Anti-HIV diphyllin glycosides from Justicia gendarussa
inferred← citeshttps://doi.org/10.1016/j.phytol.2023.09.007openalex-snapshot
Justicidin B and related lignans from two South African Monsonia species with potent activity against HeLa cervical cancer cells
inferred← citeshttps://doi.org/10.1016/j.tet.2021.132214openalex-snapshot
Triflic acid catalysed regioselective synthesis of substituted naphthalenes by benzannulation of carbonyls with alkynes
inferred← citeshttps://doi.org/10.1016/j.tetlet.2026.156149openalex-snapshot
Indium chloride catalysed annulation of arylmethyl carbonyls & arylalkynes for the synthesis of naphthalene derivatives
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c00036openalex-snapshot
Discovery of Anticancer Agents of Diverse Natural Origin
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5b00532openalex-snapshot
Cytotoxic Barrigenol-like Triterpenoids from an Extract of Cyrilla racemiflora Housed in a Repository
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b00924openalex-snapshot
Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b00004openalex-snapshot
Potent Inhibitor of Drug-Resistant HIV-1 Strains Identified from the Medicinal Plant Justicia gendarussa
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b01079openalex-snapshot
Crystal Structures and Human Leukemia Cell Apoptosis Inducible Activities of Parthenolide Analogues Isolated from Piptocoma rufescens
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Potential Anticancer Agents Characterized from Selected Tropical Plants
inferred← citeshttps://doi.org/10.1021/acs.orglett.1c04378openalex-snapshot
Stereoselective O-Glycosylation of Glycals with Arylboronic Acids Using Air as the Oxygen Source
inferred← citeshttps://doi.org/10.1021/acs.orglett.7b02181openalex-snapshot
Phainanolide A, Highly Modified and Oxygenated Triterpenoid from Phyllanthus hainanensis
inferred← citeshttps://doi.org/10.1021/acscatal.9b04260openalex-snapshot
Designing Synergistic Nanocatalysts for Multiple Substrate Activation: Interlattice Ag–Fe3O4 Hybrid Materials for CO2-Inserted Lactones
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NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening
inferred← citeshttps://doi.org/10.1021/ja511813gopenalex-snapshot
Phainanoids A–F, A New Class of Potent Immunosuppressive Triterpenoids with an Unprecedented Carbon Skeleton from Phyllanthus hainanensis
inferred← citeshttps://doi.org/10.1021/jm501567fopenalex-snapshot
Oleanane Triterpenes from the Flowers of Camellia japonica Inhibit Porcine Epidemic Diarrhea Virus (PEDV) Replication
inferred← citeshttps://doi.org/10.1021/np500801sopenalex-snapshot
(±)-Quassidines I and J, Two Pairs of Cytotoxic Bis-β-carboline Alkaloid Enantiomers fromPicrasma quassioides
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PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer
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Enantiomeric Lignans and Neolignans from Phyllanthus glaucus: Enantioseparation and Their Absolute Configurations
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Recent advances in research on lignans and neolignans
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Deconjugative alkylation/Heck reaction as a simple platform for dihydronaphthalene synthesis
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Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery
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Strategies for the discovery of potential anticancer agents from plants collected from Southeast Asian tropical rainforests as a case study
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Discovery and development of botanical natural products and their analogues as therapeutics for ovarian cancer
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The dichapetalins and dichapetalin-type compounds: structural diversity, bioactivity, and future research perspectives
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The Genus Phyllanthus: An Ethnopharmacological, Phytochemical, and Pharmacological Review
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-17-1195openalex-snapshot
Phyllanthusmin Derivatives Induce Apoptosis and Reduce Tumor Burden in High-Grade Serous Ovarian Cancer by Late-Stage Autophagy Inhibition
inferred← citeshttps://doi.org/10.1186/s10086-021-01947-xopenalex-snapshot
Extractives elucidation of Taiwania cryptomerioides sapwood
inferred← citeshttps://doi.org/10.1186/s43088-022-00256-6openalex-snapshot
Lignans: a versatile source of anticancer drugs
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Inhibition of DNA Topoisomerases I and II and Cytotoxicity of Compounds from Polygonum aviculare L .
inferred← citeshttps://doi.org/10.2139/ssrn.4823138openalex-snapshot
Phytochemical Characterization and Cytotoxic Activity of Haplophyllum Megalanthum: An Endemic Plant from Turkey
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Immune Modulation of Asian Folk Herbal Medicines and Related Chemical Components for Cancer Management
inferred← citeshttps://doi.org/10.2174/1389557522666220117122718openalex-snapshot
Antiviral, Anticancer and Hypotensive Potential of Diphyllin Glycosides and their Mechanisms of Action
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Discovery of Anticancer Agents of Diverse Natural Origin
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Transition Metal-Mediated Annulation Approaches for Synthesis of Arylnaphthalene Lignan Lactones
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A Synthetic Disaccharide Derivative of Diphyllin, TAARD, Activates Human Natural Killer Cells to Secrete Interferon-Gamma via Toll-Like Receptor-Mediated NF-κB and STAT3 Signaling Pathways
inferred← citeshttps://doi.org/10.3390/horticulturae10020195openalex-snapshot
Phyllanthus Lignans: A Review of Biological Activity and Elicitation
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Bioactivities and Mechanisms of Action of Diphyllin and Its Derivatives: A Comprehensive Systematic Review
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Cytokines, the Tumor Microenvironment, and Selected Plant-Derived Natural Products
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Bioactive small-molecule constituents of Lao plants
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