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Isolation, Structure Elucidation, Relative LC-MS Response, and in Vitro Toxicity of Azaspiracids from the Dinoflagellate Azadinium spinosum

https://doi.org/10.1021/np500555k
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Two analogs of azaspiracid isolated from mussels, Mytilus edulis, involved in human intoxication in Ireland
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The preparation of certified calibration solutions for azaspiracid-1, -2, and -3, potent marine biotoxins found in shellfish
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A mussel tissue certified reference material for multiple phycotoxins. Part 2: liquid chromatography–mass spectrometry, sample extraction and quantitation procedures
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Quantitative analysis of azaspiracids in Azadinium spinosum cultures
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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
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Effect of Azadinium spinosum on the feeding behaviour and azaspiracid accumulation of Mytilus edulis
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Field and mesocosm trials on passive sampling for the study of adsorption and desorption behaviour of lipophilic toxins with a focus on OA and DTX1
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Characterization of azaspiracids in plankton size-fractions and isolation of an azaspiracid-producing dinoflagellate from the North Sea
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Comparative accumulation and composition of lipophilic marine biotoxins in passive samplers and in mussels (M. edulis) on the West Coast of Ireland
inferredcites →https://doi.org/10.1016/j.hal.2011.06.010openalex-snapshot
The role of Azadinium spinosum (Dinophyceae) in the production of azaspiracid shellfish poisoning in mussels
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First record of the genus Azadinium (Dinophyceae) from the Shetland Islands, including the description of Azadinium polongum sp. nov.
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Morphology, phylogeny and azaspiracid profile of Azadinium poporum (Dinophyceae) from the China Sea
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Isolation of pectenotoxin-2 from Dinophysis acuta and its conversion to pectenotoxin-2 seco acid, and preliminary assessment of their acute toxicities
inferredcites →https://doi.org/10.1016/j.toxicon.2005.02.014openalex-snapshot
Teratogenic effects of azaspiracid-1 identified by microinjection of Japanese medaka (Oryzias latipes) embryos
inferredcites →https://doi.org/10.1016/j.toxicon.2005.02.015openalex-snapshot
Cytotoxic and cytoskeletal effects of azaspiracid-1 on mammalian cell lines
inferredcites →https://doi.org/10.1016/j.toxicon.2006.04.015openalex-snapshot
Characterization of polar brevetoxin derivatives isolated from Karenia brevis cultures and natural blooms
inferredcites →https://doi.org/10.1016/j.toxicon.2009.02.008openalex-snapshot
Isolation of azaspiracid-2 from a marine sponge Echinoclathria sp. as a potent cytotoxin
inferredcites →https://doi.org/10.1016/j.toxicon.2009.09.009openalex-snapshot
Azaspiracid poisoning (AZP) toxins in shellfish: Toxicological and health considerations
inferredcites →https://doi.org/10.1016/j.toxicon.2010.08.007openalex-snapshot
Sub-lethal dosing of azaspiracid-1 in female NMRI mice
inferredcites →https://doi.org/10.1016/j.toxicon.2012.05.007openalex-snapshot
New azaspiracids in Amphidomataceae (Dinophyceae)
inferredcites →https://doi.org/10.1016/j.toxicon.2013.01.010openalex-snapshot
Dissolved azaspiracids are absorbed and metabolized by blue mussels (Mytilus edulis)
inferredcites →https://doi.org/10.1016/s0041-0101(01)00226-4openalex-snapshot
Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels
inferredcites →https://doi.org/10.1021/ac048385hopenalex-snapshot
Quantitative 1H NMR with External Standards: Use in Preparation of Calibration Solutions for Algal Toxins and Other Natural Products
inferredcites →https://doi.org/10.1021/ja981413ropenalex-snapshot
Azaspiracid, a New Marine Toxin Having Unique Spiro Ring Assemblies, Isolated from Irish Mussels, Mytilus edulis
inferredcites →https://doi.org/10.1021/jf2048788openalex-snapshot
Improved Isolation Procedure for Azaspiracids from Shellfish, Structural Elucidation of Azaspiracid-6, and Stability Studies
inferredcites →https://doi.org/10.1021/jf8025138openalex-snapshot
Formation of Azaspiracids-3, -4, -6, and -9 via Decarboxylation of Carboxyazaspiracid Metabolites from Shellfish
inferredcites →https://doi.org/10.1021/tx200553popenalex-snapshot
Comparative Effects of the Marine Algal Toxins Azaspiracid-1, -2, and -3 on Jurkat T Lymphocyte Cells
inferredcites →https://doi.org/10.1021/tx3001785openalex-snapshot
Induction of Apoptosis Pathways in Several Cell Lines following Exposure to the Marine Algal Toxin Azaspiracid
inferredcites →https://doi.org/10.1021/tx300283topenalex-snapshot
Marine Algal Toxin Azaspiracid Is an Open-State Blocker of hERG Potassium Channels
inferredcites →https://doi.org/10.1021/tx400434bopenalex-snapshot
Epimers of Azaspiracids: Isolation, Structural Elucidation, Relative LC-MS Response, and in Vitro Toxicity of 37-epi-Azaspiracid-1
inferredcites →https://doi.org/10.1080/09670260802578534openalex-snapshot
Azadinium spinosumgen. et sp. nov. (Dinophyceae) identified as a primary producer of azaspiracid toxins
inferredcites →https://doi.org/10.1111/jpy.12104openalex-snapshot
A new potentially toxic A zadinium species ( D inophyceae) from the M editerranean Sea, A . dexteroporum sp. nov.
inferredcites →https://doi.org/10.1201/b16662-27openalex-snapshot
Azaspiracids: Chemistry, Biosynthesis, Metabolism, and Detection
inferredcites →https://doi.org/10.1271/bbb.65.740openalex-snapshot
Structures of Azaspiracid Analogs, Azaspiracid-4 and Azaspiracid-5, Causative Toxins of Azaspiracid Poisoning in Europe
inferredcites →https://doi.org/10.3390/md10061360openalex-snapshot
Production and Isolation of Azaspiracid-1 and -2 from Azadinium spinosum Culture in Pilot Scale Photobioreactors
inferredcites →https://doi.org/10.3390/md6020039openalex-snapshot
Azaspiracid Shellfish Poisoning: A Review on the Chemistry, Ecology, and Toxicology with an Emphasis on Human Health Impacts
inferredcites →https://doi.org/10.3390/md8041011openalex-snapshot
Biosynthesis and Molecular Genetics of Polyketides in Marine Dinoflagellates

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Mediterranean Azadinium dexteroporum (Dinophyceae) produces six novel azaspiracids and azaspiracid-35: a structural study by a multi-platform mass spectrometry approach
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Co-localisation of Azaspiracid Analogs with the Dinoflagellate Species Azadinium spinosum and Amphidoma languida in the Southwest of Ireland
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Diversity, distribution, and azaspiracids of Amphidomataceae (Dinophyceae) along the Norwegian coast
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Two novel azaspiracids from Azadinium poporum, and a comprehensive compilation of azaspiracids produced by Amphidomataceae, (Dinophyceae)
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Variability and profiles of lipophilic toxins in bivalves from Great Britain during five and a half years of monitoring: azaspiracids and yessotoxins
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Temporal and spatial distribution of Azadinium species in the inland and coastal waters of the Pacific northwest in 2014–2018
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Structure and toxicity of AZA-59, an azaspiracid shellfish poisoning toxin produced by Azadinium poporum (Dinophyceae)
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Production of the dinoflagellate Amphidoma languida in a large scale photobioreactor and structure elucidation of its main metabolite AZA-39
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Diversity of amphidomatacean dinoflagellates in Japan, with a description of Azadinium inconspicuum sp. nov. and azaspiracid components in Azadinium poporum ribotypes
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New azaspiracid analogues detected as bi-charged ions in Azadinium poporum (Amphidomataceae, Dinophyceae) isolated from Japanese coastal waters
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Coordination regulation of enhanced performance reveals the tolerance mechanism of Chlamys farreri to azaspiracid toxicity
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Fatty acid esters of azaspiracids identified in mussels (Mytilus edulis) using liquid chromatography-high resolution mass spectrometry
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Azaspiracid-59 accumulation and transformation in mussels (Mytilus edulis) after feeding with Azadinium poporum (Dinophyceae)
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Structure elucidation and in vitro toxicity of AZA-40, an azaspiracid isobaric to AZA-1
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In Vitro Metabolism of Azaspiracids 1–3 with a Hepatopancreatic Fraction from Blue Mussels (Mytilus edulis)
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Effects of Heating on Proportions of Azaspiracids 1–10 in Mussels (Mytilus edulis) and Identification of Carboxylated Precursors for Azaspiracids 5, 10, 13, and 15
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Selective Extraction and Purification of Azaspiracids from Blue Mussels (Mytilus edulis) Using Boric Acid Gel
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A Practical ELISA for Azaspiracids in Shellfish via Development of a New Plate-Coating Antigen
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Evaluation of the shucking of certain species of scallops contaminated with lipophilic toxins with a view to the production of edible parts meeting the safety requirements foreseen in the Union legislation
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Evaluation of the shucking of certain species of scallops contaminated with domoic acid with a view to the production of edible parts meeting the safety requirements foreseen in the Union legislation
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Multiple New Strains of Amphidomataceae (Dinophyceae) from the North Atlantic Revealed a High Toxin Profile Variability of Azadinium spinosum and a New Non-Toxigenic Az. cf. spinosum
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