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Fecal Metabolomics of Healthy Breast-Fed versus Formula-Fed Infants before and during In Vitro Batch Culture Fermentation

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/j.1536-4801.2000.tb02655.xopenalex-snapshot
Analysis of Intestinal Flora Development in Breast-Fed and Formula-Fed Infants by Using Molecular Identification and Detection Methods
inferredcites →https://doi.org/10.1002/mnfr.200700150openalex-snapshot
In vitro fermentability of human milk oligosaccharides by several strains of bifidobacteria
inferredcites →https://doi.org/10.1016/j.carres.2011.08.009openalex-snapshot
Occurrence of oligosaccharides in feces of breast-fed babies in their first six months of life and the corresponding breast milk
inferredcites →https://doi.org/10.1017/s0954422410000065openalex-snapshot
Breast-v.formula-feeding: impacts on the digestive tract and immediate and long-term health effects
inferredcites →https://doi.org/10.1021/ac901536hopenalex-snapshot
Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems
inferredcites →https://doi.org/10.1021/jf305056fopenalex-snapshot
In Vitro Fermentation Characteristics of Select Nondigestible Oligosaccharides by Infant Fecal Inocula
inferredcites →https://doi.org/10.1021/jf9044205openalex-snapshot
Consumption of Human Milk Oligosaccharides by Gut-Related Microbes
inferredcites →https://doi.org/10.1021/pr100554mopenalex-snapshot
Dietary Modulation of Gut Functional Ecology Studied by Fecal Metabonomics
inferredcites →https://doi.org/10.1038/nrgastro.2009.35openalex-snapshot
Principles and clinical implications of the brain–gut–enteric microbiota axis
inferredcites →https://doi.org/10.1073/pnas.1010529108openalex-snapshot
Normal gut microbiota modulates brain development and behavior
inferredcites →https://doi.org/10.1079/bjn2002625openalex-snapshot
Intestinal flora during the first months of life: new perspectives
inferredcites →https://doi.org/10.1079/bjn2002814openalex-snapshot
Protein-degradation products and bacterial enzyme activities in faeces of breast-fed and formula-fed infants
inferredcites →https://doi.org/10.1093/ajcn/87.3.534openalex-snapshot
Early differences in fecal microbiota composition in children may predict overweight
inferredcites →https://doi.org/10.1111/j.1365-2672.2012.05344.xopenalex-snapshot
γ-Aminobutyric acid production by culturable bacteria from the human intestine
inferredcites →https://doi.org/10.1111/j.1399-3038.2012.01286.xopenalex-snapshot
Effect of lactose on gut microbiota and metabolome of infants with cow’s milk allergy
inferredcites →https://doi.org/10.1126/scitranslmed.3005114openalex-snapshot
Melamine-Induced Renal Toxicity Is Mediated by the Gut Microbiota
inferredcites →https://doi.org/10.1136/gut.27.10.1173openalex-snapshot
Studies of the free faecal amines of infants with gastroenteritis and of healthy infants.
inferredcites →https://doi.org/10.1146/annurev.nutr.20.1.699openalex-snapshot
Oligosaccharides in Human Milk: Structural, Functional, and Metabolic Aspects
inferredcites →https://doi.org/10.1186/1471-2180-13-6openalex-snapshot
Ammonia production by human faecal bacteria, and the enumeration, isolation and characterization of bacteria capable of growth on peptides and amino acids
inferredcites →https://doi.org/10.1186/1758-2946-2-9openalex-snapshot
Organization of GC/MS and LC/MS metabolomics data into chemical libraries
inferredcites →https://doi.org/10.1203/pdr.0b013e3181fc9d13openalex-snapshot
Effect of Milk Formula Protein Content on Intestinal Barrier Function in a Porcine Model of LBW Neonates
inferredcites →https://doi.org/10.1371/journal.pone.0019594openalex-snapshot
The Level of Protein in Milk Formula Modifies Ileal Sensitivity to LPS Later in Life in a Piglet Model
inferredcites →https://doi.org/10.1371/journal.pone.0020647openalex-snapshot
Fecal Microbiota in Premature Infants Prior to Necrotizing Enterocolitis
inferredcites →https://doi.org/10.1371/journal.pone.0052876openalex-snapshot
Distortions in Development of Intestinal Microbiota Associated with Late Onset Sepsis in Preterm Infants
inferredcites →https://doi.org/10.1371/journal.ppat.1000549openalex-snapshot
The Microbiota and Allergies/Asthma
inferredcites →https://doi.org/10.1542/peds.2005-2824openalex-snapshot
Factors Influencing the Composition of the Intestinal Microbiota in Early Infancy
inferredcites →https://doi.org/10.1590/s0212-16112011000600015openalex-snapshot
Diet creates metabolic niches in the "immature gut" that shape microbial communities.
inferredcites →https://doi.org/10.2217/14622416.9.4.383openalex-snapshot
Analysis of the Adult Human Plasma Metabolome
inferredcites →https://doi.org/10.3389/fnsys.2013.00001openalex-snapshot
Cross-frequency interaction of the eye-movement related LFP signals in V1 of freely viewing monkeys
inferredcites →https://doi.org/10.3389/fnsys.2013.00009openalex-snapshot
Cerebral Low-Molecular Metabolites Influenced by Intestinal Microbiota: A Pilot Study
inferredcites →https://doi.org/10.3945/jn.113.175828openalex-snapshot
Dietary Protein Excess during Neonatal Life Alters Colonic Microbiota and Mucosal Response to Inflammatory Mediators Later in Life in Female Pigs
inferredcites →https://doi.org/10.4161/gmic.26041openalex-snapshot
Crying in infants
inferredcites →https://doi.org/10.5772/31277openalex-snapshot
Software Techniques for Enabling High-Throughput Analysis of Metabolomic Datasets

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4865602openalex-extracted
Glycation Compounds in Human Milk
inferred← citeshttps://doi.org/10.1002/9781119138105.ch6openalex-snapshot
In VivoandIn VitroStudies on Dietary Fiber and Gut Health
inferred← citeshttps://doi.org/10.1002/mnfr.201900035openalex-snapshot
Metabolic Fate and Distribution of 2´‐Fucosyllactose: Direct Influence on Gut Microbial Activity but not on Brain
inferred← citeshttps://doi.org/10.1007/978-0-387-85960-6_37openalex-snapshot
Catecholamines and Catecholamine Receptors in Cardiovascular Behavioral Medicine
inferred← citeshttps://doi.org/10.1007/978-3-030-55482-8_9openalex-snapshot
The Enzymology of Human Milk
inferred← citeshttps://doi.org/10.1007/978-981-96-6389-7_40openalex-snapshot
Machine Learning on Metabolomic Profiles from Fecal to Identify Plant-Based Food Intake
inferred← citeshttps://doi.org/10.1007/s00253-023-12436-0openalex-snapshot
Butyrogenic effect of galactosyl and mannosyl carbohydrates and their regulation on piglet intestinal microbiota
inferred← citeshttps://doi.org/10.1007/s11011-026-01848-2openalex-snapshot
A perspective for alzheimer disease from gut microbiota-associated NMR-based fecal metabolomics: a study with 5XFAD mice
inferred← citeshttps://doi.org/10.1007/s11306-014-0714-2openalex-snapshot
Explorative study of metabolic adaptations to various dietary calcium intakes and cereal sources on serum metabolome and hepatic gene expression in juvenile pigs
inferred← citeshttps://doi.org/10.1007/s13668-019-00284-2openalex-snapshot
Metabolomic Insights into the Effects of Breast Milk Versus Formula Milk Feeding in Infants
inferred← citeshttps://doi.org/10.1016/b978-0-12-823485-3.00040-3openalex-snapshot
References
inferred← citeshttps://doi.org/10.1016/b978-0-323-88445-7.16001-4openalex-snapshot
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A review on human fecal metabolomics: Methods, applications and the human fecal metabolome database
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Properties of hydrolyzed guar gum fermented in vitro with pig fecal inocula and its favorable impacts on microbiota
inferred← citeshttps://doi.org/10.1016/j.chom.2022.04.005openalex-snapshot
Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants
inferred← citeshttps://doi.org/10.1016/j.chom.2025.07.003openalex-snapshot
Amino acid competition shapes Acinetobacter baumannii gut carriage
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inferred← citeshttps://doi.org/10.1016/j.foodchem.2024.141265openalex-snapshot
Protein-bound and free glycation compounds in human milk: A comparative study with minimally processed infant formula and pasteurized bovine milk
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inferred← citeshttps://doi.org/10.1021/ac503619qopenalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.analchem.5b02688openalex-snapshot
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inferred← citeshttps://doi.org/10.1038/s41390-019-0647-6openalex-snapshot
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Personalizing protein nourishment
inferred← citeshttps://doi.org/10.1080/14789450.2019.1703679openalex-snapshot
Clinical insights gained through metabolomic analysis of human breast milk
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Microbial metabolites as modulators of the infant gut microbiome and host-microbial interactions in early life
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The propionate-GPR41 axis in infancy protects from subsequent bronchial asthma onset
inferred← citeshttps://doi.org/10.1080/19490976.2023.2221426openalex-snapshot
Key bacterial taxa determine longitudinal dynamics of aromatic amino acid catabolism in infants’ gut
inferred← citeshttps://doi.org/10.1080/19490976.2023.2241209openalex-snapshot
Breastfeeding and the major fermentation metabolite lactate determine occurrence of Peptostreptococcaceae in infant feces
inferred← citeshttps://doi.org/10.1080/29933935.2026.2620183openalex-snapshot
Using in vitro gastrointestinal (GI) tract digestive products to investigate fermentation dynamics of Lactobacillus rhamnosus GG, Bifidobacterium animalis subsp. lactis BB-12, and Escherichia coli
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Comparative prebiotic potential of galacto- and fructo-oligosaccharides, native inulin, and acacia gum in Kenyan infant gut microbiota during iron supplementation
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Fecal Short‐Chain Fatty Acids of Very‐Low‐Birth‐Weight Preterm Infants Fed Expressed Breast Milk or Formula
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Impact of 2′‐fucosyllactose on adult gut microbiota composition and metabolome based on colonic fermentation and prebiotic quantitative evaluation
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Human Milk-Fed Piglets Have a Distinct Small Intestine and Circulatory Metabolome Profile Relative to That of Milk Formula-Fed Piglets
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Early-life fecal microbiome and metabolome dynamics in response to an intervention with infant formula containing specific prebiotics and postbiotics
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Gut Microbiota Development: Influence of Diet from Infancy to Toddlerhood
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Secretory IgA in Colostrum and Neonatal Feces is Not Associated With Maternal Nutrient Intake in Newborns From Healthy Mothers
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Diet-Related Metabolic Perturbations of Gut Microbial Shikimate Pathway-Tryptamine-tRNA Aminoacylation-Protein Synthesis in Human Health and Disease
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Milk oligosaccharide-driven persistence of Bifidobacterium pseudocatenulatum modulates local and systemic microbial metabolites upon synbiotic treatment in conventionally colonized mice
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Analytical insights, modulation and compositional dynamics of the feline gut microbiota: a review
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Phylogenetic and Metabolic Tracking of Gut Microbiota during Perinatal Development
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Investigating colonization patterns of the infant gut microbiome during the introduction of solid food and weaning from breastmilk: A cohort study protocol
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Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for “Precision Medicine and Pharmacometabolomics Task Group”—The Metabolomics Society Initiative)
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Effect of Bovine Milk Fat-based Infant Formulae on Microbiota, Metabolites and Stool Parameters in Healthy Term Infants in A Randomized, Crossover, Placebo-controlled Trial
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Human milk oligosaccharide consumption by probiotic and human-associated bifidobacteria and lactobacilli
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Relationship between Milk Microbiota, Bacterial Load, Macronutrients, and Human Cells during Lactation
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Gut Microbiota Profiling: Metabolomics Based Approach to Unravel Compounds Affecting Human Health
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Effects of early postnatal life nutritional interventions on immune-microbiome interactions in the gastrointestinal tract and implications for brain development and function
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Fecal Short-Chain Fatty Acid Variations by Breastfeeding Status in Infants at 4 Months: Differences in Relative versus Absolute Concentrations
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Inefficient Metabolism of the Human Milk Oligosaccharides Lacto-N-tetraose and Lacto-N-neotetraose Shifts Bifidobacterium longum subsp. infantis Physiology
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Breastfeeding Affects Concentration of Faecal Short Chain Fatty Acids During the First Year of Life: Results of the Systematic Review and Meta-Analysis
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Human Breast Milk: Exploring the Linking Ring Among Emerging Components
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Role of human milk oligosaccharide metabolizing bacteria in the development of atopic dermatitis/eczema
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Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer
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Structure Characterization and Potential Probiotic Effects of Sorghum and Oat Resistant Dextrins
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Association of Cesarean Delivery and Formula Supplementation with the Stool Metabolome of 6-Week-Old Infants
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Effectiveness and Safety of a Probiotic-Mixture for the Treatment of Infantile Colic: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial with Fecal Real-Time PCR and NMR-Based Metabolomics Analysis
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Human Breast Milk NMR Metabolomic Profile across Specific Geographical Locations and Its Association with the Milk Microbiota
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Dietary Intake Influences Metabolites in Healthy Infants: A Scoping Review
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Special Diets in Infants and Children and Impact on Gut Microbioma
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The Effect of Breast Milk Microbiota on the Composition of Infant Gut Microbiota: A Cohort Study
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The Role of Diet and Nutritional Interventions for the Infant Gut Microbiome
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Comparing In Vitro Faecal Fermentation Methods as Surrogates for Phage Therapy Application
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Asthma Metabolomics: The Missing Step for Translating Bench Work into the Clinic
inferred← citeshttps://doi.org/10.6084/m9.figshare.24040727openalex-snapshot
Additional file 1 of Milk oligosaccharide-driven persistence of Bifidobacterium pseudocatenulatum modulates local and systemic microbial metabolites upon synbiotic treatment in conventionally colonized mice
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