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Use of Ligand Based Models for Protein Domains To Predict Novel Molecular Targets and Applications To Triage Affinity Chromatography Data

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.292.4.419openalex-snapshot
"Promiscuous" Anticancer Drugs That Hit Multiple Targets May Thwart Resistance
inferredcites →https://doi.org/10.1002/1097-0134(20010501)43:2<217::aid-prot1032>3.0.co;2-gopenalex-snapshot
Ligand-protein inverse docking and its potential use in the computer search of protein targets of a small molecule
inferredcites →https://doi.org/10.1002/cmdc.200700026openalex-snapshot
Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off‐Target Effects from Chemical Structure
inferredcites →https://doi.org/10.1002/cmdc.200700036openalex-snapshot
Modeling Promiscuity Based on in vitro Safety Pharmacology Profiling Data
inferredcites →https://doi.org/10.1002/prot.10625openalex-snapshot
Recovering the true targets of specific ligands by virtual screening of the protein data bank
inferredcites →https://doi.org/10.1002/prot.20777openalex-snapshot
Rough set‐based proteochemometrics modeling of G‐protein‐coupled receptor‐ligand interactions
inferredcites →https://doi.org/10.1002/prot.21163openalex-snapshot
Generalized modeling of enzyme–ligand interactions using proteochemometrics and local protein substructures
inferredcites →https://doi.org/10.1016/j.bmc.2004.03.052openalex-snapshot
Design and synthesis of novel hydrophilic spacers for the reduction of nonspecific binding proteins on affinity resins
inferredcites →https://doi.org/10.1016/j.ddtec.2004.08.009openalex-snapshot
Fishing for targets: novel approaches using small molecule baits
inferredcites →https://doi.org/10.1016/j.ddtec.2006.12.008openalex-snapshot
In silico target fishing: Predicting biological targets from chemical structure
inferredcites →https://doi.org/10.1016/j.jchromb.2006.12.047openalex-snapshot
Chemical proteomics for drug discovery based on compound-immobilized affinity chromatography
inferredcites →https://doi.org/10.1016/s1074-5521(00)00124-1openalex-snapshot
Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors
inferredcites →https://doi.org/10.1016/s1359-6446(03)02902-7openalex-snapshot
Rediscovering the sweet spot in drug discovery
inferredcites →https://doi.org/10.1021/ac026196yopenalex-snapshot
Quantitative Chemical Proteomics for Identifying Candidate Drug Targets
inferredcites →https://doi.org/10.1021/ac060213sopenalex-snapshot
Specific Affinity Extraction Method for Small Molecule-Binding Proteins
inferredcites →https://doi.org/10.1021/ci020345wopenalex-snapshot
The Signature Molecular Descriptor. 1. Using Extended Valence Sequences in QSAR and QSPR Studies
inferredcites →https://doi.org/10.1021/ci060003gopenalex-snapshot
Prediction of Biological Targets for Compounds Using Multiple-Category Bayesian Models Trained on Chemogenomics Databases
inferredcites →https://doi.org/10.1021/ci6005504openalex-snapshot
Understanding False Positives in Reporter Gene Assays: in Silico Chemogenomics Approaches To Prioritize Cell-Based HTS Data
inferredcites →https://doi.org/10.1021/jm049461bopenalex-snapshot
Rapid Computational Identification of the Targets of Protein Kinase Inhibitors
inferredcites →https://doi.org/10.1021/jm050362nopenalex-snapshot
A Critical Assessment of Docking Programs and Scoring Functions
inferredcites →https://doi.org/10.1021/jm051139topenalex-snapshot
Robust Ligand-Based Modeling of the Biological Targets of Known Drugs
inferredcites →https://doi.org/10.1021/jm060902wopenalex-snapshot
Bridging Chemical and Biological Space: “Target Fishing” Using 2D and 3D Molecular Descriptors
inferredcites →https://doi.org/10.1038/nbt1068openalex-snapshot
A small molecule–kinase interaction map for clinical kinase inhibitors
inferredcites →https://doi.org/10.1038/nbt1328openalex-snapshot
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
inferredcites →https://doi.org/10.1038/nbt1358openalex-snapshot
A quantitative analysis of kinase inhibitor selectivity
inferredcites →https://doi.org/10.1038/nbt999openalex-snapshot
Ligand selectivity and competition between enzymes in silico
inferredcites →https://doi.org/10.1038/nrd1343openalex-snapshot
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
inferredcites →https://doi.org/10.1038/nrm1683openalex-snapshot
Scoring proteomes with proteotypic peptide probes
inferredcites →https://doi.org/10.1073/pnas.0510562103openalex-snapshot
Role of β-arrestin 1 in the metastatic progression of colorectal cancer
inferredcites →https://doi.org/10.1074/jbc.274.16.10677openalex-snapshot
Identification of NSF as a β-Arrestin1-binding Protein
inferredcites →https://doi.org/10.1074/jbc.m207294200openalex-snapshot
β-Arrestin2 Is Critically Involved in CXCR4-mediated Chemotaxis, and This Is Mediated by Its Enhancement of p38 MAPK Activation
inferredcites →https://doi.org/10.1093/bioinformatics/btm580openalex-snapshot
Genome scale enzyme–metabolite and drug–target interaction predictions using the signature molecular descriptor
inferredcites →https://doi.org/10.1093/bioinformatics/btn238openalex-snapshot
A Bayesian estimator of protein–protein association probabilities
inferredcites →https://doi.org/10.1093/nar/29.1.37openalex-snapshot
The InterPro database, an integrated documentation resource for protein families, domains and functional sites
inferredcites →https://doi.org/10.1093/nar/gki106openalex-snapshot
InterPro, progress and status in 2005
inferredcites →https://doi.org/10.1093/nar/gkl841openalex-snapshot
New developments in the InterPro database
inferredcites →https://doi.org/10.1111/j.2517-6161.1995.tb02031.xopenalex-snapshot
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
inferredcites →https://doi.org/10.1124/pr.56.3.3openalex-snapshot
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
inferredcites →https://doi.org/10.1126/science.1075762openalex-snapshot
The Protein Kinase Complement of the Human Genome
inferredcites →https://doi.org/10.1158/0008-5472.can-04-3303openalex-snapshot
Multidrug Transporter ABCG2 Prevents Tumor Cell Death Induced by the Epidermal Growth Factor Receptor Inhibitor Iressa (ZD1839, Gefitinib)
inferredcites →https://doi.org/10.1186/1471-2105-7-152openalex-snapshot
Domain-based small molecule binding site annotation
inferredcites →https://doi.org/10.2174/138620707782507313openalex-snapshot
Chemogenomic Data Analysis: Prediction of Small-Molecule Targets and the Advent of Biological Fingerprints
inferredcites →https://doi.org/10.4161/cbt.6.3.3763openalex-snapshot
Association of variant ABCG2 and the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients
inferredcites →https://doi.org/10.4161/cc.5.18.3212openalex-snapshot
Emerging Roles of β-Arrestins

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/cmdc.201500123openalex-snapshot
Target Fishing by Cross‐Docking to Explain Polypharmacological Effects
inferred← citeshttps://doi.org/10.1002/minf.201200002openalex-snapshot
Large‐Scale QSAR in Target Prediction and Phenotypic HTS Assessment
inferred← citeshttps://doi.org/10.1016/j.apsusc.2019.04.106openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.drudis.2015.08.001openalex-snapshot
Identifying compound efficacy targets in phenotypic drug discovery
inferred← citeshttps://doi.org/10.1016/j.jprot.2011.05.011openalex-snapshot
From in silico target prediction to multi-target drug design: Current databases, methods and applications
inferred← citeshttps://doi.org/10.1021/acs.jcim.5b00555openalex-snapshot
Open Source Bayesian Models. 3. Composite Models for Prediction of Binned Responses
inferred← citeshttps://doi.org/10.1021/ci300435jopenalex-snapshot
In Silico Target Predictions: Defining a Benchmarking Data Set and Comparison of Performance of the Multiclass Naïve Bayes and Parzen-Rosenblatt Window
inferred← citeshttps://doi.org/10.1021/pr1001274openalex-snapshot
Combined Comparative and Chemical Proteomics on the Mechanisms of levo-Tetrahydropalmatine-Induced Antinociception in the Formalin Test
inferred← citeshttps://doi.org/10.1038/nrd2876openalex-snapshot
Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds
inferred← citeshttps://doi.org/10.1039/9781788018982-00231openalex-snapshot
Machine Learning in Drug Design
inferred← citeshttps://doi.org/10.1039/c5nj02729bopenalex-snapshot
Nano-MoO 3 -mediated synthesis of bioactive thiazolidin-4-ones acting as anti-bacterial agents and their mode-of-action analysis using in silico target prediction, docking and similarity searching
inferred← citeshttps://doi.org/10.1093/bioinformatics/btu792openalex-snapshot
Retrieval of Enterobacteriaceae drug targets using singular value decomposition
inferred← citeshttps://doi.org/10.1146/annurev-pharmtox-010611-134639openalex-snapshot
Chemical Genetics–Based Target Identification in Drug Discovery
inferred← citeshttps://doi.org/10.1186/1471-2105-13-s17-s11openalex-snapshot
Mapping small molecule binding data to structural domains
inferred← citeshttps://doi.org/10.1186/s12859-017-1586-zopenalex-snapshot
MOST: most-similar ligand based approach to target prediction
inferred← citeshttps://doi.org/10.1186/s13321-015-0063-9openalex-snapshot
Proteochemometric modelling coupled to in silico target prediction: an integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules
inferred← citeshttps://doi.org/10.1186/s13321-015-0098-yopenalex-snapshot
Target prediction utilising negative bioactivity data covering large chemical space
inferred← citeshttps://doi.org/10.7243/2050-2273-1-6openalex-snapshot
Characterizing protein domain associations by Small-molecule ligand binding
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