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Evolved Quorum Sensing Regulator, LsrR, for Altered Switching Functions
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
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Protein secondary structure prediction based on position-specific scoring matrices 1 1Edited by G. Von Heijne
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Optimizing non-natural protein function with directed evolution
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Development of the quorum sensing biotechnological toolbox
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Quorum sensing and bacterial cross-talk in biotechnology
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Directed evolution: new parts and optimized function
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Developing next generation antimicrobials by intercepting AI-2 mediated quorum sensing
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Crystal Structure of the Full-Length Sorbitol Operon Regulator SorC from Klebsiella pneumoniae: Structural Evidence for a Novel Transcriptional Regulation Mechanism
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Engineering microbial consortia: a new frontier in synthetic biology
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Autonomous induction of recombinant proteins by minimally rewiring native quorum sensing regulon of E. coli
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Directed evolution as a powerful synthetic biology tool
inferredcites →https://doi.org/10.1016/s0092-8674(02)00829-2openalex-snapshot
Parallel Quorum Sensing Systems Converge to Regulate Virulence in Vibrio cholerae
inferredcites →https://doi.org/10.1016/s1369-5274(00)00180-6openalex-snapshot
Mechanisms of transcriptional repression
inferredcites →https://doi.org/10.1021/cb3006402openalex-snapshot
Directed Evolution of the Quorum-Sensing Regulator EsaR for Increased Signal Sensitivity
inferredcites →https://doi.org/10.1021/cb600444hopenalex-snapshot
Phosphorylation and Processing of the Quorum-Sensing Molecule Autoinducer-2 in Enteric Bacteria
inferredcites →https://doi.org/10.1021/ja102587wopenalex-snapshot
Synthetic Analogs Tailor Native AI-2 Signaling Across Bacterial Species
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An Expeditious Synthesis of DPD and Boron Binding Studies
inferredcites →https://doi.org/10.1038/cr.2009.122openalex-snapshot
Quieting cross talk – the quorum sensing regulator LsrR as a possible target for fighting bacterial infections
inferredcites →https://doi.org/10.1038/cr.2009.91openalex-snapshot
LsrR-binding site recognition and regulatory characteristics in Escherichia coli AI-2 quorum sensing
inferredcites →https://doi.org/10.1038/msb.2012.71openalex-snapshot
Autonomous bacterial localization and gene expression based on nearby cell receptor density
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Synthetic biology: applications come of age
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The second wave of synthetic biology: from modules to systems
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Interspecies and interkingdom communication mediated by bacterial quorum sensing
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Activation and repression of transcription initiation in bacteria
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The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum‐sensing signal molecule
inferredcites →https://doi.org/10.1046/j.1365-2958.2003.03781.xopenalex-snapshot
Lsr‐mediated transport and processing of AI‐2 in Salmonella typhimurium
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Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication
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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
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Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production
inferredcites →https://doi.org/10.1074/jbc.m112.417634openalex-snapshot
Structural Basis for Phosphorylated Autoinducer-2 Modulation of the Oligomerization State of the Global Transcription Regulator LsrR from Escherichia coli
inferredcites →https://doi.org/10.1080/08927010902853516openalex-snapshot
Mini-review: quorum sensing in the marine environment and its relationship to biofouling
inferredcites →https://doi.org/10.1093/bioinformatics/18.9.1250openalex-snapshot
ESyPred3D: Prediction of proteins 3D structures
inferredcites →https://doi.org/10.1093/nar/gkp015openalex-snapshot
Improved tetracycline repressors for gene silencing in mycobacteria
inferredcites →https://doi.org/10.1093/protein/9.1.69openalex-snapshot
Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase
inferredcites →https://doi.org/10.1093/protein/gzt013openalex-snapshot
Engineering alternate cooperative-communications in the lactose repressor protein scaffold
inferredcites →https://doi.org/10.1107/s1744309110020695openalex-snapshot
Cloning, purification, crystallization and preliminary crystallographic analysis of LsrR fromEscherichia coli
inferredcites →https://doi.org/10.1111/j.1365-2958.1987.tb00512.xopenalex-snapshot
An E. coli promoter induced by the cessation of growth
inferredcites →https://doi.org/10.1111/j.1365-2958.2004.04159.xopenalex-snapshot
Activity reversal of Tet repressor caused by single amino acid exchanges
inferredcites →https://doi.org/10.1111/j.1365-2958.2008.06477.xopenalex-snapshot
Sinorhizobium meliloti, a bacterium lacking the autoinducer‐2 (AI‐2) synthase, responds to AI‐2 supplied by other bacteria
inferredcites →https://doi.org/10.1126/science.280.5361.295openalex-snapshot
The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm
inferredcites →https://doi.org/10.1128/aem.71.2.728-733.2005openalex-snapshot
Tetracycline-Dependent Conditional Gene Knockout in Bacillus subtilis
inferredcites →https://doi.org/10.1128/jb.00014-07openalex-snapshot
Quorum Sensing in Escherichia coli Is Signaled by AI-2/LsrR: Effects on Small RNA and Biofilm Architecture
inferredcites →https://doi.org/10.1128/jb.00216-07openalex-snapshot
Silencing Essential Protein Secretion in Mycobacterium smegmatis by Using Tetracycline Repressors
inferredcites →https://doi.org/10.1128/jb.183.17.5187-5197.2001openalex-snapshot
Quorum Sensing Is a Global Regulatory Mechanism in Enterohemorrhagic Escherichia coli O157:H7
inferredcites →https://doi.org/10.1128/jb.187.24.8350-8360.2005openalex-snapshot
luxS-Dependent Gene Regulation inEscherichia coliK-12 Revealed by Genomic Expression Profiling
inferredcites →https://doi.org/10.1128/jb.187.6.2066-2076.2005openalex-snapshot
Cyclic AMP (cAMP) and cAMP Receptor Protein Influence both Synthesis and Uptake of Extracellular Autoinducer 2 inEscherichia coli
inferredcites →https://doi.org/10.1128/jb.188.2.587-598.2006openalex-snapshot
YdgG (TqsA) Controls Biofilm Formation in Escherichia coli K-12 through Autoinducer 2 Transport
inferredcites →https://doi.org/10.1128/mbio.00102-10openalex-snapshot
Indirect Pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in Polymicrobial Otitis Media Occurs via Interspecies Quorum Signaling
inferredcites →https://doi.org/10.1146/annurev.micro.51.1.527openalex-snapshot
CELL-CELL COMMUNICATION IN GRAM-POSITIVE BACTERIA
inferredcites →https://doi.org/10.1186/1471-2148-4-36openalex-snapshot
Is autoinducer-2 a universal signal for interspecies communication: a comparative genomic and phylogenetic analysis of the synthesis and signal transduction pathways
inferredcites →https://doi.org/10.1371/journal.pcbi.1002172openalex-snapshot
LsrR Quorum Sensing “Switch” Is Revealed by a Bottom-Up Approach
inferredcites →https://doi.org/10.1371/journal.pcbi.1002637openalex-snapshot
Gene Network Homology in Prokaryotes Using a Similarity Search Approach: Queries of Quorum Sensing Signal Transduction
inferredcites →https://doi.org/10.1371/journal.pone.0037059openalex-snapshot
LsrR-Mediated Quorum Sensing Controls Invasiveness of Salmonella typhimurium by Regulating SPI-1 and Flagella Genes
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Engineering Prokaryote Synthetic Biology Biosensors
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The application of powerful promoters to enhance gene expression in industrial microorganisms
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A Synthetic Bacterial Cell-Cell Adhesion Toolbox for Programming Multicellular Morphologies and Patterns
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Application of Quorum Sensing in Metabolic Engineering
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Imaging Pseudomonas aeruginosa Biofilm Extracellular Polymer Scaffolds with Amphiphilic Carbon Dots
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Homologous Quorum Sensing Regulatory Circuit: A Dual-Input Genetic Controller for Modulating Quorum Sensing-Mediated Protein Expression in E. coli
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Dynamically Regulating Glucose Uptake to Reduce Overflow Metabolism with a Quorum-Sensing Circuit for the Efficient Synthesis of d -Pantothenic Acid in Bacillus subtilis
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Evolutionary Design of Choline-Inducible and -Repressible T7-Based Induction Systems
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Promoter Engineering in Yeast Cell Factories: Strategies, Applications, and Perspectives
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Domain-Swapped LuxR-Type Quorum Sensing Receptors Reveal Divergent Ligand-Response Mechanisms among Homologues
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Principles of genetic circuit design
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Designer cells programming quorum-sensing interference with microbes
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A scalable peptide-GPCR language for engineering multicellular communication
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Engineered systems of inducible anti-repressors for the next generation of biological programming
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Robust and flexible platform for directed evolution of yeast genetic switches
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3-Aminooxazolidinone AHL analogs as hydrolytically-stable quorum sensingagonists in Gram-negative bacteria
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Intracellular biosensor-based dynamic regulation to manipulate gene expression at the spatiotemporal level
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Insightful directed evolution ofEscherichia coliquorum sensing promoter region of thelsrACDBFGoperon: a tool for synthetic biology systems and protein expression
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Design of Asynchronous Genetic Circuits
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Multi-Faceted Characterization of a Novel LuxR-Repressible Promoter Library for Escherichia coli
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Transcription Factors as Evolvable Biosensors
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A Choline-Responsive Band-Pass gene circuit without transcriptional cascades
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Transcriptome Analysis Reveals AI-2 Relevant Genes of Multi-Drug Resistant Klebsiella pneumoniae in Response to Eugenol at Sub-MIC
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