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Indirect Pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in Polymicrobial Otitis Media Occurs via Interspecies Quorum Signaling

https://doi.org/10.1128/mbio.00102-10
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Evidence of Bacterial Metabolic Activity in Culture-Negative Otitis Media With Effusion
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Mucosal Biofilm Formation on Middle-Ear Mucosa in the Chinchilla Model of Otitis Media
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Direct Detection of Bacterial Biofilms on the Middle-Ear Mucosa of Children With Chronic Otitis Media
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Innate and Induced Resistance Mechanisms of Bacterial Biofilms
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The incidence, prevalence and burden of OM in unselected children aged 1–8 years followed by weekly otoscopy through the “common cold” season
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" INDIRECT PATHOGENICITY " OF PENICILLINASE-PRODUCING ENTEROBACTERIA IN CHRONIC BRONCHIAL INFECTIONS
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PCR-based detection of bacterial DNA after antimicrobial treatment is indicative of persistent, viable bacteria in the chinchilla model of otitis media
inferredcites →https://doi.org/10.1016/s0264-410x(00)00271-1openalex-snapshot
The burden of otitis media
inferredcites →https://doi.org/10.1038/nrmicro1916openalex-snapshot
Establishing bacterial communities by 'word of mouth': LuxS and autoinducer 2 in biofilm development
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Use of the complete genome sequence information of Haemophilus influenzae strain Rd to investigate lipopolysaccharide biosynthesis
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The LuxS‐dependent autoinducer AI‐2 controls the expression of an ABC transporter that functions in AI‐2 uptake in Salmonella typhimurium
inferredcites →https://doi.org/10.1046/j.1365-2958.2003.03803.xopenalex-snapshot
Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication
inferredcites →https://doi.org/10.1046/j.1462-5822.2002.00180.xopenalex-snapshot
Molecular and cellular determinants of non-typeable Haemophilus influenzae adherence and invasion
inferredcites →https://doi.org/10.1073/pnas.96.4.1639openalex-snapshot
Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production
inferredcites →https://doi.org/10.1074/jbc.m110986200openalex-snapshot
Haemophilus influenzae Type b Strain A2 Has Multiple Sialyltransferases Involved in Lipooligosaccharide Sialylation
inferredcites →https://doi.org/10.1078/1438-4221-00196openalex-snapshot
Mechanisms of antibiotic resistance in bacterial biofilms
inferredcites →https://doi.org/10.1086/647933openalex-snapshot
Acute Otitis Media Caused byMoraxella catarrhalis:Epidemiologic and Clinical Characteristics
inferredcites →https://doi.org/10.1093/infdis/170.6.1613openalex-snapshot
Experimental Evidence For Moraxella-Induced Penicillin Neutralization In Pneumococcal Pneumonia
inferredcites →https://doi.org/10.1093/jac/6.3.307openalex-snapshot
Indirect pathogenicity
inferredcites →https://doi.org/10.1097/00006454-200009000-00034openalex-snapshot
Recurrent and persistent otitis media
inferredcites →https://doi.org/10.1097/inf.0b013e318154b273openalex-snapshot
Bacterial Biofilms in Otitis Media
inferredcites →https://doi.org/10.1097/moo.0b013e3282b97327openalex-snapshot
The role of biofilms in otolaryngologic infections: update 2007
inferredcites →https://doi.org/10.1111/j.1365-2672.2008.03910.xopenalex-snapshot
Autoinducer-2 is produced in saliva-fed flow conditions relevant to natural oral biofilms
inferredcites →https://doi.org/10.1111/j.1365-2958.1994.tb00422.xopenalex-snapshot
Multiple signalling systems controlling expression of luminescence in Vibrio harveyi : sequence and function of genes encoding a second sensory pathway
inferredcites →https://doi.org/10.1111/j.1365-2958.2006.05202.xopenalex-snapshot
Autoinducer 2: a concentration‐dependent signal for mutualistic bacterial biofilm growth
inferredcites →https://doi.org/10.1111/j.1365-2958.2008.06477.xopenalex-snapshot
Sinorhizobium meliloti, a bacterium lacking the autoinducer‐2 (AI‐2) synthase, responds to AI‐2 supplied by other bacteria
inferredcites →https://doi.org/10.1126/science.280.5361.295openalex-snapshot
The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm
inferredcites →https://doi.org/10.1126/science.284.5418.1318openalex-snapshot
Bacterial Biofilms: A Common Cause of Persistent Infections
inferredcites →https://doi.org/10.1126/science.7542800openalex-snapshot
Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd
inferredcites →https://doi.org/10.1128/aac.42.10.2521openalex-snapshot
Interaction of Streptococcus pneumoniae and Moraxella catarrhalis : Investigation of the Indirect Pathogenic Role of β-Lactamase-Producing Moraxellae by Use of a Continuous-Culture Biofilm System
inferredcites →https://doi.org/10.1128/aac.48.3.890-896.2004openalex-snapshot
Killing by Ampicillin and Ofloxacin Induces Overlapping Changes in Escherichia coli Transcription Profile
inferredcites →https://doi.org/10.1128/aac.49.6.2467-2473.2005openalex-snapshot
Use of Confocal Microscopy To Analyze the Rate of Vancomycin Penetration through Staphylococcus aureus Biofilms
inferredcites →https://doi.org/10.1128/iai.00320-09openalex-snapshot
LuxS Promotes Biofilm Maturation and Persistence of Nontypeable Haemophilus influenzae In Vivo via Modulation of Lipooligosaccharides on the Bacterial Surface
inferredcites →https://doi.org/10.1128/iai.00402-07openalex-snapshot
Autoinducer 2 Is Required for Biofilm Growth ofAggregatibacter(Actinobacillus)actinomycetemcomitans
inferredcites →https://doi.org/10.1128/iai.01691-06openalex-snapshot
Phosphorylcholine Decreases Early Inflammation and Promotes the Establishment of Stable Biofilm Communities of Nontypeable Haemophilus influenzae Strain 86-028NP in a Chinchilla Model of Otitis Media
inferredcites →https://doi.org/10.1128/iai.01741-05openalex-snapshot
TheActinobacillus actinomycetemcomitansRibose Binding Protein RbsB Interacts with Cognate and Heterologous Autoinducer 2 Signals
inferredcites →https://doi.org/10.1128/iai.56.2.331-335.1988openalex-snapshot
Frequency of fimbriation of nontypable Haemophilus influenzae and its ability to adhere to chinchilla and human respiratory epithelium
inferredcites →https://doi.org/10.1128/iai.64.9.3920-3924.1996openalex-snapshot
Outer membrane protein B1, an iron-repressible protein conserved in the outer membrane of Moraxella (Branhamella) catarrhalis, binds human transferrin
inferredcites →https://doi.org/10.1128/iai.68.9.5261-5268.2000openalex-snapshot
Lipooligosaccharide P k (Galα1-4Galβ1-4Glc) Epitope of Moraxella catarrhalis Is a Factor in Resistance to Bactericidal Activity Mediated by Normal Human Serum
inferredcites →https://doi.org/10.1128/iai.72.1.106-113.2004openalex-snapshot
Sialylation of Lipooligosaccharides Promotes Biofilm Formation by Nontypeable Haemophilus influenzae
inferredcites →https://doi.org/10.1128/iai.73.6.3210-3218.2005openalex-snapshot
Role of Sialic Acid and Complex Carbohydrate Biosynthesis in Biofilm Formation by Nontypeable Haemophilus influenzae in the Chinchilla Middle Ear
inferredcites →https://doi.org/10.1128/iai.74.3.1828-1836.2006openalex-snapshot
Biofilm Growth Increases Phosphorylcholine Content and Decreases Potency of NontypeableHaemophilus influenzaeEndotoxins
inferredcites →https://doi.org/10.1128/jb.00387-07openalex-snapshot
Differential Interaction ofAggregatibacter(Actinobacillus)actinomycetemcomitansLsrB and RbsB Proteins with Autoinducer 2
inferredcites →https://doi.org/10.1128/jb.00532-07openalex-snapshot
Phosphorylcholine Expression by NontypeableHaemophilus influenzaeCorrelates with Maturation of Biofilm Communities In Vitro and In Vivo
inferredcites →https://doi.org/10.1128/jb.187.1.238-248.2005openalex-snapshot
Regulation of Uptake and Processing of the Quorum-Sensing Autoinducer AI-2 in Escherichia coli
inferredcites →https://doi.org/10.1128/jcm.35.11.2854-2858.1997openalex-snapshot
Use of multiplex PCR for simultaneous detection of four bacterial species in middle ear effusions
inferredcites →https://doi.org/10.1128/jcm.37.6.1771-1776.1999openalex-snapshot
The Calgary Biofilm Device: New Technology for Rapid Determination of Antibiotic Susceptibilities of Bacterial Biofilms
inferredcites →https://doi.org/10.1139/m80-003openalex-snapshot
Purine metabolism in Neisseria gonorrhoeae: the requirement for hypoxanthine
inferredcites →https://doi.org/10.1146/annurev.bioeng.10.061807.160536openalex-snapshot
Bacterial Quorum Sensing: Signals, Circuits, and Implications for Biofilms and Disease
inferredcites →https://doi.org/10.1146/annurev.cellbio.21.012704.131001openalex-snapshot
QUORUM SENSING: Cell-to-Cell Communication in Bacteria
inferredcites →https://doi.org/10.1164/rccm.200509-1459ocopenalex-snapshot
Haemophilus influenzae Forms Biofilms on Airway Epithelia
inferredcites →https://doi.org/10.1177/000348949610500311openalex-snapshot
Experimental Otitis Media with Moraxella (Branhamella) Catarrhalis
inferredcites →https://doi.org/10.1542/9781610025034-part01-the_diagnosisopenalex-snapshot
The Diagnosis and Management of Acute Otitis Media
inferredcites →https://doi.org/10.1542/peds.108.1.1openalex-snapshot
Reducing Antibiotic Use in Children: A Randomized Trial in 12 Practices
inferredcites →https://doi.org/10.1542/peds.113.5.1451openalex-snapshot
Diagnosis and Management of Acute Otitis Media
inferredcites →https://doi.org/10.1542/peds.99.3.318openalex-snapshot
Otitis Media in 2253 Pittsburgh-Area Infants: Prevalence and Risk Factors During the First Two Years of Life
inferredcites →https://doi.org/10.2165/00003495-198600313-00020openalex-snapshot
Branhamella catarrhalis as an Indirect Pathogen
inferredcites →https://doi.org/10.2165/00003495-198600313-00021openalex-snapshot
Direct and Indirect Pathogenicity of Branhamella catarrhalis
inferredcites →https://doi.org/10.2165/00003495-198631020-00001openalex-snapshot
Current Classification of Antiarrhythmic Drugs as a Guide to Their Rational Clinical Use

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Monoclonal antibodies that target extracellular DNABII proteins or the type IV pilus of nontypeable Haemophilus influenzae (NTHI) worked additively to disrupt 2-genera biofilms
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inferred← citeshttps://doi.org/10.1093/femspd/ftu011openalex-snapshot
Nonencapsulated Streptococcus pneumoniae causes otitis media during single-species infection and during polymicrobial infection with nontypeable Haemophilus influenzae
inferred← citeshttps://doi.org/10.1093/femsre/fuag020openalex-snapshot
Bacterial quorum-sensing systems in cell–cell communication
inferred← citeshttps://doi.org/10.1093/infdis/jis024openalex-snapshot
Nasopharyngeal Microbiota in Infants With Acute Otitis Media
inferred← citeshttps://doi.org/10.1093/infdis/jit289openalex-snapshot
Mixed Pneumococcal–Nontypeable Haemophilus influenzae Otitis Media Is a Distinct Clinical Entity With Unique Epidemiologic Characteristics and Pneumococcal Serotype Distribution
inferred← citeshttps://doi.org/10.1093/ismejo/wraf104openalex-snapshot
Pathogen-pathogen interactions during co-infections
inferred← citeshttps://doi.org/10.1097/mcp.0000000000000419openalex-snapshot
How can the cystic fibrosis respiratory microbiome influence our clinical decision-making?
inferred← citeshttps://doi.org/10.1098/rsos.180810openalex-snapshot
Mutations in bacterial genes induce unanticipated changes in the relationship between bacterial pathogens in experimental otitis media
inferred← citeshttps://doi.org/10.1099/mic.0.000523openalex-snapshot
Virulence determinants of Moraxella catarrhalis: distribution and considerations for vaccine development
inferred← citeshttps://doi.org/10.1099/mic.0.042929-0openalex-snapshot
Colonization of healthy children by Moraxella catarrhalis is characterized by genotype heterogeneity, virulence gene diversity and co-colonization with Haemophilus influenzae
inferred← citeshttps://doi.org/10.1101/2020.03.26.010959openalex-snapshot
Pseudomonas aeruginosa enhances the efficacy of norfloxacin against Staphylococcus aureus biofilms
inferred← citeshttps://doi.org/10.1111/1574-6941.12034openalex-snapshot
LuxS influencesEscherichia colibiofilm formation through autoinducer-2-dependent and autoinducer-2-independent modalities
inferred← citeshttps://doi.org/10.1111/1574-6968.12203openalex-snapshot
Novel concepts in nontypeableHaemophilus influenzaebiofilm formation
inferred← citeshttps://doi.org/10.1111/1751-7915.70218openalex-snapshot
Polymicrobial Biofilms: Interkingdom Interactions, Resistance and Therapeutic Strategies
inferred← citeshttps://doi.org/10.1111/2049-632x.12073openalex-snapshot
Haemophilus influenzae and Streptococcus pneumoniae : living together in a biofilm
inferred← citeshttps://doi.org/10.1111/2049-632x.12129openalex-snapshot
Residence ofStreptococcus pneumoniaeandMoraxella catarrhaliswithin polymicrobial biofilm promotes antibiotic resistance and bacterial persistencein vivo
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2011.07831.xopenalex-snapshot
RbsB (NTHI_0632) mediates quorum signal uptake in nontypeable Haemophilus influenzae strain 86-028NP
inferred← citeshttps://doi.org/10.1111/j.1574-6976.2012.00345.xopenalex-snapshot
AI-2-mediated signalling in bacteria
inferred← citeshttps://doi.org/10.1111/jam.15338openalex-snapshot
Intraspecific and interspecific extracellular metabolites remodel biofilms formed by thermophilic spoilage bacteria
inferred← citeshttps://doi.org/10.1111/mmi.14699openalex-snapshot
Friends or enemies? The complicated relationship between Pseudomonas aeruginosa and Staphylococcus aureus
inferred← citeshttps://doi.org/10.1111/php.13241openalex-snapshot
Photoinactivation of Moraxella catarrhalis Using 405‐nm Blue Light: Implications for the Treatment of Otitis Media
inferred← citeshttps://doi.org/10.1128/aac.01186-19openalex-snapshot
Regulatory Mechanisms of the LuxS/AI-2 System and Bacterial Resistance
inferred← citeshttps://doi.org/10.1128/aac.02636-13openalex-snapshot
Sheltering Effect and Indirect Pathogenesis of Carbapenem-Resistant Acinetobacter baumannii in Polymicrobial Infection
inferred← citeshttps://doi.org/10.1128/aem.01051-12openalex-snapshot
Upper Respiratory Tract Microbial Communities, Acute Otitis Media Pathogens, and Antibiotic Use in Healthy and Sick Children
inferred← citeshttps://doi.org/10.1128/aem.01931-25openalex-snapshot
Microbial interactions in facilitating antibiotic activity and resistance evolution
inferred← citeshttps://doi.org/10.1128/cmr.00010-18openalex-snapshot
Translating Recent Microbiome Insights in Otitis Media into Probiotic Strategies
inferred← citeshttps://doi.org/10.1128/cmr.00013-11openalex-snapshot
Polymicrobial Interactions: Impact on Pathogenesis and Human Disease
inferred← citeshttps://doi.org/10.1128/cmr.00084-16openalex-snapshot
Options and Limitations in Clinical Investigation of Bacterial Biofilms
inferred← citeshttps://doi.org/10.1128/cvi.00089-15openalex-snapshot
Vaccines for Nontypeable Haemophilus influenzae: the Future Is Now
inferred← citeshttps://doi.org/10.1128/cvi.00090-15openalex-snapshot
Therapeutic Transcutaneous Immunization with a Band-Aid Vaccine Resolves Experimental Otitis Media
inferred← citeshttps://doi.org/10.1128/iai.00506-18openalex-snapshot
Autoinducer 2 (AI-2) Production by Nontypeable Haemophilus influenzae 86-028NP Promotes Expression of a Predicted Glycosyltransferase That Is a Determinant of Biofilm Maturation, Prevention of Dispersal, and Persistence In Vivo
inferred← citeshttps://doi.org/10.1128/iai.00568-21openalex-snapshot
Nontypeable Haemophilus influenzae Infection Impedes Pseudomonas aeruginosa Colonization and Persistence in Mouse Respiratory Tract
inferred← citeshttps://doi.org/10.1128/iai.00660-10openalex-snapshot
Nontypeable Haemophilus influenzae Initiates Formation of Neutrophil Extracellular Traps
inferred← citeshttps://doi.org/10.1128/iai.00934-19openalex-snapshot
From Nursery to Nursing Home: Emerging Concepts in Clostridioides difficile Pathogenesis
inferred← citeshttps://doi.org/10.1128/iai.01745-14openalex-snapshot
Identification of an Outer Membrane Lipoprotein Involved in Nasopharyngeal Colonization by Moraxella catarrhalis in an Animal Model
inferred← citeshttps://doi.org/10.1128/iai.01832-14openalex-snapshot
Substrate Binding Protein SBP2 of a Putative ABC Transporter as a Novel Vaccine Antigen of Moraxella catarrhalis
inferred← citeshttps://doi.org/10.1128/iai.02185-14openalex-snapshot
Role of the Oligopeptide Permease ABC Transporter of Moraxella catarrhalis in Nutrient Acquisition and Persistence in the Respiratory Tract
inferred← citeshttps://doi.org/10.1128/iai.05186-11openalex-snapshot
The LuxS-Dependent Quorum-Sensing System Regulates Early Biofilm Formation by Streptococcus pneumoniae Strain D39
inferred← citeshttps://doi.org/10.1128/iai.05918-11openalex-snapshot
Use of the Chinchilla Model for Nasopharyngeal Colonization To Study Gene Expression by Moraxella catarrhalis
inferred← citeshttps://doi.org/10.1128/jb.00139-11openalex-snapshot
The Moraxella catarrhalis Nitric Oxide Reductase Is Essential for Nitric Oxide Detoxification
inferred← citeshttps://doi.org/10.1128/jb.00159-20openalex-snapshot
Pseudomonas aeruginosa PA14 Enhances the Efficacy of Norfloxacin against Staphylococcus aureus Newman Biofilms
inferred← citeshttps://doi.org/10.1128/jb.00530-19openalex-snapshot
“It Takes a Village”: Mechanisms Underlying Antimicrobial Recalcitrance of Polymicrobial Biofilms
inferred← citeshttps://doi.org/10.1128/jb.02006-14openalex-snapshot
Staphylococcus aureus Alters Growth Activity, Autolysis, and Antibiotic Tolerance in a Human Host-Adapted Pseudomonas aeruginosa Lineage
inferred← citeshttps://doi.org/10.1128/jcm.00035-14openalex-snapshot
Airway Microbiome Dynamics in Exacerbations of Chronic Obstructive Pulmonary Disease
inferred← citeshttps://doi.org/10.1128/jcm.00756-10openalex-snapshot
Adenoid Reservoir for Pathogenic Biofilm Bacteria
inferred← citeshttps://doi.org/10.1128/jcm.01146-16openalex-snapshot
Moraxella catarrhalis Might Be More Common than Expected in Acute Otitis Media in Young Finnish Children
inferred← citeshttps://doi.org/10.1128/mbio.00245-10openalex-snapshot
Microbial Communities of the Upper Respiratory Tract and Otitis Media in Children
inferred← citeshttps://doi.org/10.1128/mbio.00464-23openalex-snapshot
Rothia from the Human Nose Inhibit Moraxella catarrhalis Colonization with a Secreted Peptidoglycan Endopeptidase
inferred← citeshttps://doi.org/10.1128/mbio.00782-16openalex-snapshot
A Commensal Bacterium Promotes Virulence of an Opportunistic Pathogen via Cross-Respiration
inferred← citeshttps://doi.org/10.1128/mbio.01501-19openalex-snapshot
Pseudomonas aeruginosa Increases the Sensitivity of Biofilm-Grown Staphylococcus aureus to Membrane-Targeting Antiseptics and Antibiotics
inferred← citeshttps://doi.org/10.1128/mbio.02423-18openalex-snapshot
Antibodies against the Majority Subunit (PilA) of the Type IV Pilus of Nontypeable Haemophilus influenzae Disperse Moraxella catarrhalis from a Dual-Species Biofilm
inferred← citeshttps://doi.org/10.1128/msphere.00242-25openalex-snapshot
Host-pathogen interaction profiling of nontypeable Haemophilus influenzae and Moraxella catarrhalis coinfection of bronchial epithelial cells
inferred← citeshttps://doi.org/10.1128/msystems.00352-20openalex-snapshot
Experimental Evolution In Vivo To Identify Selective Pressures during Pneumococcal Colonization
inferred← citeshttps://doi.org/10.1128/spectrum.04835-22openalex-snapshot
A 4-Hydroxybenzoic Acid-Mediated Signaling System Controls the Physiology and Virulence of Shigella sonnei
inferred← citeshttps://doi.org/10.11575/prism/27331openalex-snapshot
Phenotypic and Genotypic Characterization of the Streptococci Isolated from Sputum of Adult Cystic Fibrosis Patients
inferred← citeshttps://doi.org/10.1159/000513325openalex-snapshot
Role of Upper Respiratory Microbiota and Virome in Childhood Rhinitis and Wheeze: Collegium Internationale Allergologicum Update 2021
inferred← citeshttps://doi.org/10.1177/0194599812459636openalex-snapshot
Panel 5: Microbiology and Immunology Panel
inferred← citeshttps://doi.org/10.1177/0194599813476257openalex-snapshot
Panel 3: Recent Advances in Anatomy, Pathology, and Cell Biology in Relation to Otitis Media Pathogenesis
inferred← citeshttps://doi.org/10.1183/16000617.0041-2019openalex-snapshot
Influence of the lung microbiome on antibiotic susceptibility of cystic fibrosis pathogens
inferred← citeshttps://doi.org/10.1186/1471-2164-12-70openalex-snapshot
Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates
inferred← citeshttps://doi.org/10.1186/1471-2180-13-140openalex-snapshot
Moraxella catarrhalis uses a twin-arginine translocation system to secrete the β-lactamase BRO-2
inferred← citeshttps://doi.org/10.1186/1471-2431-11-94openalex-snapshot
Multi-species bacterial biofilm and intracellular infection in otitis media
inferred← citeshttps://doi.org/10.1186/s12866-018-1204-xopenalex-snapshot
Quorum sensing in thermophiles: prevalence of autoinducer-2 system
inferred← citeshttps://doi.org/10.1186/s12866-019-1660-yopenalex-snapshot
The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media
inferred← citeshttps://doi.org/10.1186/s12866-026-05420-xopenalex-snapshot
Synergistic biofilm formation by the coexistence of nontypeable Haemophilus influenzae and Moraxella catarrhalis reduces amoxicillin efficacy
inferred← citeshttps://doi.org/10.1186/s12879-016-1670-4openalex-snapshot
Association of sputum microbiota profiles with severity of community-acquired pneumonia in children
inferred← citeshttps://doi.org/10.1186/s12879-018-3576-9openalex-snapshot
Probiotics Streptococcus salivarius 24SMB and Streptococcus oralis 89a interfere with biofilm formation of pathogens of the upper respiratory tract
inferred← citeshttps://doi.org/10.1186/s12931-021-01653-8openalex-snapshot
Sputum sample positivity for Haemophilus influenzae or Moraxella catarrhalis in acute exacerbations of chronic obstructive pulmonary disease: evaluation of association with positivity at earlier stable disease timepoints
inferred← citeshttps://doi.org/10.1186/s12931-022-02019-4openalex-snapshot
Safety and immunogenicity of three doses of non-typeable Haemophilus influenzae-Moraxella catarrhalis (NTHi-Mcat) vaccine when administered according to two different schedules: a phase 2, randomised, observer-blind study
inferred← citeshttps://doi.org/10.1186/s12931-025-03140-wopenalex-snapshot
Pulmonary microbiology and microbiota in adults with non-cystic fibrosis bronchiectasis: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1186/s40168-026-02366-0openalex-snapshot
Microbiota-derived propionate suppresses Salmonella virulence gene expression via LuxS quorum sensing
inferred← citeshttps://doi.org/10.1360/tb-2024-0689openalex-snapshot
Respiratory microbiome and respiratory infections
inferred← citeshttps://doi.org/10.1371/journal.pbio.2003981openalex-snapshot
Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1006179openalex-snapshot
Community interactions and spatial structure shape selection on antibiotic resistant lineages
inferred← citeshttps://doi.org/10.1371/journal.pone.0040088openalex-snapshot
Respiratory Syncytial Virus Promotes Moraxella catarrhalis-Induced Ascending Experimental Otitis Media
inferred← citeshttps://doi.org/10.1371/journal.pone.0053837openalex-snapshot
Neutrophil Extracellular Traps and Bacterial Biofilms in Middle Ear Effusion of Children with Recurrent Acute Otitis Media – A Potential Treatment Target
inferred← citeshttps://doi.org/10.1371/journal.pone.0062549openalex-snapshot
Differential Virulence Gene Expression of Group A Streptococcus Serotype M3 in Response to Co-Culture with Moraxella catarrhalis
inferred← citeshttps://doi.org/10.1371/journal.pone.0067881openalex-snapshot
Use of the Chinchilla Model to Evaluate the Vaccinogenic Potential of the Moraxella catarrhalis Filamentous Hemagglutinin-like Proteins MhaB1 and MhaB2
inferred← citeshttps://doi.org/10.1371/journal.pone.0098269openalex-snapshot
Copy Number Variation of the Beta Defensin Gene Cluster on Chromosome 8p Influences the Bacterial Microbiota within the Nasopharynx of Otitis-Prone Children
inferred← citeshttps://doi.org/10.1371/journal.pone.0195098openalex-snapshot
Carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Indonesian children: A cross-sectional study
inferred← citeshttps://doi.org/10.1371/journal.pone.0243942openalex-snapshot
Nasopharyngeal colonization with pathobionts is associated with susceptibility to respiratory illnesses in young children
inferred← citeshttps://doi.org/10.1371/journal.ppat.1007328openalex-snapshot
Function of BriC peptide in the pneumococcal competence and virulence portfolio
inferred← citeshttps://doi.org/10.14776/piv.2019.26.e24openalex-snapshot
Respiratory Microbiome in Children
inferred← citeshttps://doi.org/10.1586/eri.10.109openalex-snapshot
Interspecies bacterial communication as a target for therapy in otitis media
inferred← citeshttps://doi.org/10.2174/0118756921369289250514051055openalex-snapshot
Computational Study for the Identification of Novel Therapeutic Targets in Haemophilus influenzae by Subtractive Genomics Approach
inferred← citeshttps://doi.org/10.2217/fmb.12.80openalex-snapshot
Moraxella Catarrhalis : From Interactions with the Host Immune System to Vaccine Development
inferred← citeshttps://doi.org/10.25560/19230openalex-snapshot
The infective pulmonary exacerbation in cystic fibrosis : an ecological perspective
inferred← citeshttps://doi.org/10.33590/emjrespir/10305099openalex-snapshot
Chronic Obstructive Pulmonary Disease: Biofilm Mediated Exacerbation and Innovative Therapeutic Approaches
inferred← citeshttps://doi.org/10.3389/fcimb.2012.00058openalex-snapshot
Dps promotes survival of nontypeable Haemophilus influenzae in biofilm communities in vitro and resistance to clearance in vivo
inferred← citeshttps://doi.org/10.3389/fcimb.2012.00097openalex-snapshot
Nontypeable Haemophilus influenzae biofilms: role in chronic airway infections
inferred← citeshttps://doi.org/10.3389/fcimb.2012.00100openalex-snapshot
Quorum signaling and sensing by nontypeable Haemophilus influenzae
inferred← citeshttps://doi.org/10.3389/fcimb.2017.00344openalex-snapshot
Alloiococcus otitidis Forms Multispecies Biofilm with Haemophilus influenzae: Effects on Antibiotic Susceptibility and Growth in Adverse Conditions
inferred← citeshttps://doi.org/10.3389/fcimb.2020.00213openalex-snapshot
Bacterial Community Interactions During Chronic Respiratory Disease
inferred← citeshttps://doi.org/10.3389/fcimb.2021.764772openalex-snapshot
Innate Immunity in the Middle Ear Mucosa
inferred← citeshttps://doi.org/10.3389/fcimb.2022.775535openalex-snapshot
Predominant Bacterial and Viral Otopathogens Identified Within the Respiratory Tract and Middle Ear of Urban Australian Children Experiencing Otitis Media Are Diversely Distributed
inferred← citeshttps://doi.org/10.3389/fcimb.2022.826018openalex-snapshot
Gene Expression Regulation in Airway Pathogens: Importance for Otitis Media
inferred← citeshttps://doi.org/10.3389/fcimb.2022.969326openalex-snapshot
Biofilm aggregates and the host airway-microbial interface
inferred← citeshttps://doi.org/10.3389/fcimb.2024.1397940openalex-snapshot
Modeling airway persistent infection of Moraxella catarrhalis and nontypeable Haemophilus influenzae by using human in vitro models
inferred← citeshttps://doi.org/10.3389/fcimb.2024.1408569openalex-snapshot
Beyond antibiotics: CRISPR/Cas9 triumph over biofilm-associated antibiotic resistance infections
inferred← citeshttps://doi.org/10.3389/fimmu.2011.00013openalex-snapshot
Mucosal Immunization with the Moraxella Catarrhalis Porin M35 Induces Enhanced Bacterial Clearance from the Lung: A Possible Role for Opsonophagocytosis
inferred← citeshttps://doi.org/10.3389/fmicb.2015.00705openalex-snapshot
Pathogens protection against the action of disinfectants in multispecies biofilms
inferred← citeshttps://doi.org/10.3389/fmicb.2015.01218openalex-snapshot
Exposure to pairs of Aeromonas strains enhances virulence in the Caenorhabditis elegans infection model
inferred← citeshttps://doi.org/10.3389/fmicb.2018.03270openalex-snapshot
Binding of Elementary Bodies by the Opportunistic Fungal Pathogen Candida albicans or Soluble β-Glucan, Laminarin, Inhibits Chlamydia trachomatis Infectivity
inferred← citeshttps://doi.org/10.3389/fmicb.2019.03006openalex-snapshot
Moraxella catarrhalis Promotes Stable Polymicrobial Biofilms With the Major Otopathogens
inferred← citeshttps://doi.org/10.3389/fmicb.2020.00507openalex-snapshot
In vitro Mixed Biofilm of Streptococcus suis and Actinobacillus pleuropneumoniae Impacts Antibiotic Susceptibility and Modulates Virulence Factor Gene Expression
inferred← citeshttps://doi.org/10.3389/fmicb.2024.1345027openalex-snapshot
Otitis media: recent advances in otitis media vaccine development and model systems
inferred← citeshttps://doi.org/10.3389/frmbi.2023.1231271openalex-snapshot
Exploring the microbial landscape of the nasopharynx in children: a systematic review of studies using next generation sequencing
inferred← citeshttps://doi.org/10.3390/ani13091511openalex-snapshot
Modeling Co-Infection by Streptococcus suis and Haemophilus parasuis Reveals Influences on Biofilm Formation and Host Response
inferred← citeshttps://doi.org/10.3390/antibiotics10010003openalex-snapshot
Biofilms as Promoters of Bacterial Antibiotic Resistance and Tolerance
inferred← citeshttps://doi.org/10.3390/antibiotics11070930openalex-snapshot
The Association between Biofilm Formation and Antimicrobial Resistance with Possible Ingenious Bio-Remedial Approaches
inferred← citeshttps://doi.org/10.3390/antibiotics11121731openalex-snapshot
Polymicrobial Infections and Biofilms: Clinical Significance and Eradication Strategies
inferred← citeshttps://doi.org/10.3390/antibiotics14030306openalex-snapshot
Rare or Unusual Non-Fermenting Gram-Negative Bacteria: Therapeutic Approach and Antibiotic Treatment Options
inferred← citeshttps://doi.org/10.3390/biology15151219openalex-snapshot
Nasopharyngeal Microbiome Differences Between Children with Hypertrophic Adenoids and Healthy Controls
inferred← citeshttps://doi.org/10.3390/foods15142439openalex-snapshot
Targeting Quorum Sensing to Combat Foodborne Pathogens: A Dual Strategy Against Spoilage and Pathogenesis
inferred← citeshttps://doi.org/10.3390/ijms140917694openalex-snapshot
Small Molecule Inhibitors of AI-2 Signaling in Bacteria: State-of-the-Art and Future Perspectives for Anti-Quorum Sensing Agents
inferred← citeshttps://doi.org/10.3390/microorganisms10061207openalex-snapshot
Enhanced Antibiotic Tolerance of an In Vitro Multispecies Uropathogen Biofilm Model, Useful for Studies of Catheter-Associated Urinary Tract Infections
inferred← citeshttps://doi.org/10.3390/microorganisms10101969openalex-snapshot
How does Quorum Sensing of Intestinal Bacteria Affect Our Health and Mental Status?
inferred← citeshttps://doi.org/10.3390/microorganisms11030545openalex-snapshot
Biofilm-Forming Bacteria Implicated in Complex Otitis Media in Children in the Post-Heptavalent Pneumococcal Conjugate Vaccine (PCV7) Era
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