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Structural Definition of Early Lysine and Histidine Adduction Chemistry of 4-Hydroxynonenal
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Protein Posttranslational Modification
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A mass spectrometric analysis of 4‐hydroxy‐2‐(E)‐nonenal modificationof cytochrome c
inferred← citeshttps://doi.org/10.1002/jms.1978openalex-snapshot
Isotope‐coded dimethyl tagging for differential quantification of posttranslational protein carbonylation by 4‐hydroxy‐2‐nonenal, an end‐product of lipid peroxidation
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Heterogeneity of peptide adducts with carbonylated lipid peroxidation products
inferred← citeshttps://doi.org/10.1002/jms.381openalex-snapshot
Detoxification of cytotoxic α,β‐unsaturated aldehydes by carnosine: characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle
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Formation of 4‐hydroxynonenal (4‐HNE) in frozen mackerel (Scomber scombrus) in the presence and absence of green tea
inferred← citeshttps://doi.org/10.1002/mas.10076openalex-snapshot
Mass spectrometry for detection of 4‐hydroxy‐trans‐2‐nonenal (HNE) adducts with peptides and proteins
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Intervention strategies to inhibit protein carbonylation by lipoxidation‐derived reactive carbonyls
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inferred← citeshttps://doi.org/10.1002/pmic.70032openalex-snapshot
Proteome‐Wide 4‐Hydroxy‐2‐Nonenal Signature of Oxidative Stress in the Marine Invasive Tunicate Botryllus schlosseri
inferred← citeshttps://doi.org/10.1002/prca.201600003openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.1283openalex-snapshot
Study of peptides containing modified lysine residues by tandem mass spectrometry: precursor ion scanning of hexanal‐modified peptides
inferred← citeshttps://doi.org/10.1002/rcm.2133openalex-snapshot
A strategy for distinguishing modified peptides based on post‐digestion 18 O labeling and mass spectrometry
inferred← citeshttps://doi.org/10.1002/rcm.4116openalex-snapshot
Charge‐derivatized amino acids facilitate model studies on protein side‐chain modifications by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry
inferred← citeshttps://doi.org/10.1006/bbrc.1999.0971openalex-snapshot
Marked Expression of Glutathione S-Transferase A4-4 Detoxifying 4-Hydroxy-2(E)-nonenal in the Skin of Rats Irradiated by Ultraviolet B-Band Light (UVB)
inferred← citeshttps://doi.org/10.1007/0-306-46806-9_27openalex-snapshot
Reactive Oxygen-Mediated Protein Oxidation in Aging and Disease
inferred← citeshttps://doi.org/10.1007/978-0-387-72347-1_8openalex-snapshot
Molecular Mechanisms of Environmental Atherogenesis
inferred← citeshttps://doi.org/10.1007/978-0-387-73023-3_6openalex-snapshot
Glutamate Receptors and Their Association with Other Neurochemical Parameters in Excitotoxicity
inferred← citeshttps://doi.org/10.1007/978-0-387-77300-1_8openalex-snapshot
Lipoxidation-Derived Electrophiles as Biological Reactive Intermediates
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Biofluid Biomarkers of Amyotrophic Lateral Sclerosis
inferred← citeshttps://doi.org/10.1007/978-1-4419-9940-5_6openalex-snapshot
Neurochemical Aspects of 4-Hydroxynonenal
inferred← citeshttps://doi.org/10.1007/978-3-319-28383-8_19openalex-snapshot
Detoxification of Carbonyl Compounds by Carbonyl Reductase in Neurodegeneration
inferred← citeshttps://doi.org/10.1007/s00726-003-0015-yopenalex-snapshot
Histidine and lysine as targets of oxidative modification
inferred← citeshttps://doi.org/10.1007/s10557-011-6326-4openalex-snapshot
Oxidized Low Density Lipoproteins-Do We Know Enough About Them?
inferred← citeshttps://doi.org/10.1007/s10709-025-00235-6openalex-snapshot
Identification, characterization, and evolutionary analysis of aldehyde dehydrogenase (ALDH) genes superfamily in Medicago truncatula L
inferred← citeshttps://doi.org/10.1007/s11745-001-0766-9openalex-snapshot
Effect of 4‐hydroxy‐2(E)‐nonenal on soybean lipoxygenase‐1
inferred← citeshttps://doi.org/10.1007/s11745-997-0129-6openalex-snapshot
Preparation of schiff base adducts of phosphatidylcholine core aldehydes and aminophospholipids, amino acids, and myoglobin
inferred← citeshttps://doi.org/10.1007/s11745-999-0367-7openalex-snapshot
Rapid complexing of oxoacylglycerols with amino acids peptides and aminophospholipids
inferred← citeshttps://doi.org/10.1016/0040-4039(96)00959-8openalex-snapshot
Directed approaches to reactive maillard intermediates: Formation of a novel 3-alkylamino-2-hydroxy-4-hydroxymethyl-2-cyclopenten-1-one (“Cypentodine”)
inferred← citeshttps://doi.org/10.1016/b978-0-12-816388-7.00003-6openalex-snapshot
Oxidation and Reduction of Biological Material
inferred← citeshttps://doi.org/10.1016/b978-0-9830791-6-3.50005-9openalex-snapshot
Challenges in Analyzing Lipid Oxidation
inferred← citeshttps://doi.org/10.1016/b978-1-63067-056-6.00001-xopenalex-snapshot
Analysis of Lipid and Protein Oxidation in Fats, Oils, and Foods
inferred← citeshttps://doi.org/10.1016/j.abb.2007.03.007openalex-snapshot
Isolation, purification and characterization of histidino-threosidine, a novel Maillard reaction protein crosslink from threose, lysine and histidine
inferred← citeshttps://doi.org/10.1016/j.abb.2010.09.005openalex-snapshot
Glutathione transferase A4-4 resists adduction by 4-hydroxynonenal
inferred← citeshttps://doi.org/10.1016/j.bbalip.2008.03.002openalex-snapshot
Lipid peroxidation and decomposition — Conflicting roles in plaque vulnerability and stability
inferred← citeshttps://doi.org/10.1016/j.bbalip.2014.09.013openalex-snapshot
Omega-3 polyunsaturated fatty acids and oxygenated metabolism in atherothrombosis
inferred← citeshttps://doi.org/10.1016/j.bbamem.2012.04.014openalex-snapshot
Protein modification by oxidized phospholipids and hydrolytically released lipid electrophiles: Investigating cellular responses
inferred← citeshttps://doi.org/10.1016/j.bbapap.2013.03.005openalex-snapshot
Carbonylation of mitochondrial aconitase with 4-hydroxy-2-(E)-nonenal: Localization and relative reactivity of addition sites
inferred← citeshttps://doi.org/10.1016/j.bbrc.2005.12.113openalex-snapshot
Neuroprotective role for carbonyl reductase?
inferred← citeshttps://doi.org/10.1016/j.cbi.2011.02.023openalex-snapshot
Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders
inferred← citeshttps://doi.org/10.1016/j.cbi.2011.08.007openalex-snapshot
Catabolism of 4-hydroxy-2-trans-nonenal by THP1 monocytes/macrophages and inactivation of carboxylesterases by this lipid electrophile
inferred← citeshttps://doi.org/10.1016/j.cbi.2022.109833openalex-snapshot
Carbonyl reduction of 4-oxonon-2-enal (4-ONE) by Sniffer from D. magna and D. pulex
inferred← citeshttps://doi.org/10.1016/j.cca.2012.06.012openalex-snapshot
Urinary biomarkers of oxidative status
inferred← citeshttps://doi.org/10.1016/j.chemphyslip.2008.09.004openalex-snapshot
Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions
inferred← citeshttps://doi.org/10.1016/j.chemphyslip.2014.03.002openalex-snapshot
Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids
inferred← citeshttps://doi.org/10.1016/j.foodchem.2014.11.154openalex-snapshot
LC–MS investigations on interactions between isolated β-lactoglobulin peptides and lipid oxidation product malondialdehyde
inferred← citeshttps://doi.org/10.1016/j.foodchem.2025.145913openalex-snapshot
Unraveling the covalent binding mechanisms of aroma compounds with porcine proteins: A mass spectrometry, proteomics, and conformational analysis approach
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2004.06.012openalex-snapshot
Reactions of 4-hydroxynonenal with proteins and cellular targets
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2009.08.002openalex-snapshot
Differential distribution of 4-hydroxynonenal adducts to sulfur and nitrogen residues in blood proteins as revealed using Raney nickel and gas chromatography–mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2010.10.694openalex-snapshot
Posttranslational modification and regulation of glutamate–cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenal
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2011.02.037openalex-snapshot
A method for detection of 4-hydroxy-2-nonenal adducts in proteins
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2011.06.027openalex-snapshot
Lipid peroxidation and neurodegenerative disease
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2012.11.010openalex-snapshot
Aldehyde dehydrogenases in cellular responses to oxidative/electrophilicstress
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2014.02.008openalex-snapshot
Glutathionylated 4-hydroxy-2-(E)-alkenal enantiomers in rat organs and their contributions toward the disposal of 4-hydroxy-2-(E)-nonenal in rat liver
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2015.02.001openalex-snapshot
NADP+-dependent dehydrogenase activity of carbonyl reductase on glutathionylhydroxynonanal as a new pathway for hydroxynonenal detoxification
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2015.10.405openalex-snapshot
Identification of an unstable 4-hydroxynoneal modification on the 20S proteasome subunit α7 by recombinant antibody technology.
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.09.021openalex-snapshot
4-Hydroxynonenal dependent alteration of TRPV1-mediated coronary microvascular signaling
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.12.038openalex-snapshot
Proatherogenic effects of 4-hydroxynonenal
inferred← citeshttps://doi.org/10.1016/j.idairyj.2004.01.003openalex-snapshot
Hexanal and t-2-hexenal form covalent bonds with whey proteins and sodium caseinate in aqueous solution
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2016.01.053openalex-snapshot
Immunochemical studies on HNE-modified HSA: Anti-HNE–HSA antibodies as a probe for HNE damaged albumin in SLE
inferred← citeshttps://doi.org/10.1016/j.jprot.2013.06.004openalex-snapshot
Lipoxidation adducts with peptides and proteins: Deleterious modifications or signaling mechanisms?
inferred← citeshttps://doi.org/10.1016/j.lwt.2025.117772openalex-snapshot
Saponin and hexanal in pea (Pisum sativum) protein isolates: A comparative study of isoelectric precipitation and ultrafiltration
inferred← citeshttps://doi.org/10.1016/j.mad.2006.08.006openalex-snapshot
Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteomic approach
inferred← citeshttps://doi.org/10.1016/j.mam.2012.09.001openalex-snapshot
Protein damage, repair and proteolysis
inferred← citeshttps://doi.org/10.1016/j.neuro.2006.07.018openalex-snapshot
Inhibition of the oxidative metabolism of 3,4-dihydroxyphenylacetaldehyde, a reactive intermediate of dopamine metabolism, by 4-hydroxy-2-nonenal
inferred← citeshttps://doi.org/10.1016/j.nut.2005.01.006openalex-snapshot
Preventive action of green tea from changes in the liver antioxidant abilities of different aged rats intoxicated with ethanol
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2019.107418openalex-snapshot
Isolevuglandins as mediators of disease and the development of dicarbonyl scavengers as pharmaceutical interventions
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Re-arrangements of 4-[(4H-1,2,4-triazol-4-ylimino)methyl]phenol with different inorganic anions: Crystal structure and fluorescence properties
inferred← citeshttps://doi.org/10.1016/j.redox.2021.101901openalex-snapshot
Protein oxidation - Formation mechanisms, detection and relevance as biomarkers in human diseases
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2019.03.190openalex-snapshot
17-β-Estradiol: Significant reduction of its toxicity in water treated by photocatalysis
inferred← citeshttps://doi.org/10.1016/j.tetlet.2008.08.025openalex-snapshot
Organocatalytic asymmetric 1,4-addition of organoboronic acids to γ-hydroxy α,β-unsaturated aldehyde: facile synthesis of chiral β-substituted γ-lactones
inferred← citeshttps://doi.org/10.1016/s0006-291x(02)02545-7openalex-snapshot
Carnosine is a quencher of 4-hydroxy-nonenal: through what mechanism of reaction?
inferred← citeshttps://doi.org/10.1016/s0006-291x(03)00817-9openalex-snapshot
Singlet oxygen-mediated damage to proteins and its consequences
inferred← citeshttps://doi.org/10.1016/s0006-291x(03)01412-8openalex-snapshot
Maillard reaction-like lysine modification by a lipid peroxidation product: immunochemical detection of protein-bound 2-hydroxyheptanal in vivo
inferred← citeshttps://doi.org/10.1016/s0006-2952(98)00266-4openalex-snapshot
U-101033E (2,4-diaminopyrrolopyrimidine), a potent inhibitor of membrane lipid peroxidation as assessed by the production of 4-hydroxynonenal, malondialdehyde, and 4-hydroxynonenal– protein adducts
inferred← citeshttps://doi.org/10.1016/s0006-8993(97)01224-9openalex-snapshot
Advanced lipid peroxidation end-products in Alexander's disease1Send reprint requests to M.A. Smith, 2085 Adelbert Road, Cleveland, OH 44106, USA. Tel.: +216-368-3670; fax: +216-368-8964.1
inferred← citeshttps://doi.org/10.1016/s0009-2797(02)00178-3openalex-snapshot
Covalent adduction of nucleophilic amino acids by 4-hydroxynonenal and 4-oxononenal
inferred← citeshttps://doi.org/10.1016/s0009-2797(02)00182-5openalex-snapshot
Oxidation of 4-hydroxynonenal in rat brain slices
inferred← citeshttps://doi.org/10.1016/s0009-2797(98)00072-6openalex-snapshot
Incubation of superoxide dismutase with malondialdehyde and 4-hydroxy-2-nonenal forms new active isoforms and adducts. An evaluation of xenobiotics in fish
inferred← citeshttps://doi.org/10.1016/s0009-3084(03)00048-3openalex-snapshot
Reaction of Nα-hippuryllysine with 2-hydroxyheptanal: a model for lysine-directed protein modifications by lipid peroxidation
inferred← citeshttps://doi.org/10.1016/s0009-3084(99)00043-2openalex-snapshot
Synthesis of (E)-9-(1-pyrenyl)-4-hydroxynon-2-enal, a fluorescent probe of the (E)-4-hydroxynon-2-enal with retained biological properties
inferred← citeshttps://doi.org/10.1016/s0022-2275(20)33458-1openalex-snapshot
Macrophage receptors responsible for distinct recognition of low density lipoprotein containing pyrrole or pyridinium adducts: models of oxidized low density lipoprotein
inferred← citeshttps://doi.org/10.1016/s0076-6879(00)19053-6openalex-snapshot
[51] Detection of 4-hydroxy-2-nonenol adducts following lipid peroxidation from ozone exposure
inferred← citeshttps://doi.org/10.1016/s0098-2997(03)00012-8openalex-snapshot
Fate of 4-hydroxynonenal in vivo: disposition and metabolic pathways
inferred← citeshttps://doi.org/10.1016/s0098-2997(03)00025-6openalex-snapshot
Hydroxynonenal, toxic carbonyls, and Alzheimer disease
inferred← citeshttps://doi.org/10.1016/s0163-7827(03)00014-6openalex-snapshot
4-Hydroxy-2-nonenal: a product and mediator of oxidative stress
inferred← citeshttps://doi.org/10.1016/s0169-328x(01)00214-5openalex-snapshot
Neurochemical consequences of kainate-induced toxicity in brain: involvement of arachidonic acid release and prevention of toxicity by phospholipase A2 inhibitors
inferred← citeshttps://doi.org/10.1016/s0197-0186(98)00062-xopenalex-snapshot
Effects of 4-hydroxynonenal, a lipid peroxidation product, on dopamine transport and Na+/K+ ATPase in rat striatal synaptosomes
inferred← citeshttps://doi.org/10.1016/s0891-5849(98)00149-xopenalex-snapshot
Covalent modifications of aminophospholipids by 4-hydroxynonenal
inferred← citeshttps://doi.org/10.1016/s0925-4439(97)00091-4openalex-snapshot
Non-conventional modification of low density lipoproteins: chemical models for macrophage recognition of oxidized LDL
inferred← citeshttps://doi.org/10.1016/s1011-1344(01)00208-1openalex-snapshot
Photo-oxidation of proteins and its role in cataractogenesis
inferred← citeshttps://doi.org/10.1016/s1537-1891(02)00170-2openalex-snapshot
Hydroxy alkenal phospholipids regulate inflammatory functions of endothelial cells
inferred← citeshttps://doi.org/10.1016/s1568-461x(01)80047-8openalex-snapshot
Photo-oxidation of proteins and its consequences
inferred← citeshttps://doi.org/10.1021/ac000267gopenalex-snapshot
Determination of α- and β-Hydroxycarbonyls and Dicarbonyls in Snow and Rain Samples by GC/FID and GC/MS Employing Benzyl Hydroxyl Oxime Derivatization
inferred← citeshttps://doi.org/10.1021/ac020443gopenalex-snapshot
Immunoaffinity Purification and Characterization of 4-Hydroxy-2-nonenal- and Malondialdehyde-Modified Peptides by Electrospray Ionization Tandem Mass Spectrometry
inferred← citeshttps://doi.org/10.1021/ac0303822openalex-snapshot
Identification of 4-Hydroxy-2-nonenal-Modified Peptides within Unfractionated Digests Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry
inferred← citeshttps://doi.org/10.1021/ac0617971openalex-snapshot
Proteomic Mapping of 4-Hydroxynonenal Protein Modification Sites by Solid-Phase Hydrazide Chemistry and Mass Spectrometry
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c05466openalex-snapshot
Mitochondria-Directing Fluorogenic Probe: An Efficient Amyloid Marker for Imaging Lipid Metabolite-Induced Protein Aggregation in Live Cells and Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1021/acs.biochem.1c00478openalex-snapshot
Lipid Peroxidation Products HNE and ONE Promote and Stabilize Alpha-Synuclein Oligomers by Chemical Modifications
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.1c00408openalex-snapshot
Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.6b00374openalex-snapshot
Electrophilic Modification of PKM2 by 4-Hydroxynonenal and 4-Oxononenal Results in Protein Cross-Linking and Kinase Inhibition
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.6b00428openalex-snapshot
Soft Cysteine Signaling Network: The Functional Significance of Cysteine in Protein Function and the Soft Acids/Bases Thiol Chemistry That Facilitates Cysteine Modification
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.6b00443openalex-snapshot
Reaction Mechanism of Covalent Modification of Phosphatidylethanolamine Lipids by Reactive Aldehydes 4-Hydroxy-2-nonenal and 4-Oxo-2-nonenal
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.7b00002openalex-snapshot
Structure and Oxidation of Pyrrole Adducts Formed between Aflatoxin B2a and Biological Amines
inferred← citeshttps://doi.org/10.1021/acs.chemrev.7b00698openalex-snapshot
Redox Signaling by Reactive Electrophiles and Oxidants
inferred← citeshttps://doi.org/10.1021/acs.jafc.5b01502openalex-snapshot
4-Hydroxy-2-nonenal (4-HNE) and Its Lipation Product 2-Pentylpyrrole Lysine (2-PPL) in Peanuts
inferred← citeshttps://doi.org/10.1021/acs.joc.8b02231openalex-snapshot
Revisited Mechanism of Reaction between a Model Lysine Amino Acid Side Chain and 4-Hydroxynonenal in Different Solvent Environments
inferred← citeshttps://doi.org/10.1021/bi061853sopenalex-snapshot
The Oxidative Stress Metabolite 4-Hydroxynonenal Promotes Alzheimer Protofibril Formation
inferred← citeshttps://doi.org/10.1021/jf0010533openalex-snapshot
Inhibition of Low-Density Lipoprotein Oxidation by Carnosine and Histidine
inferred← citeshttps://doi.org/10.1021/jf0490403openalex-snapshot
Origin and Mechanistic Pathways of Formation of the Parent FuranA Food Toxicant
inferred← citeshttps://doi.org/10.1021/jf3026277openalex-snapshot
Mass Spectrometric Evidence of Malonaldehyde and 4-Hydroxynonenal Adductions to Radical-Scavenging Soy Peptides
inferred← citeshttps://doi.org/10.1021/jf980780jopenalex-snapshot
Ability of Carnosine and Other Skeletal Muscle Components To Quench Unsaturated Aldehydic Lipid Oxidation Products
inferred← citeshttps://doi.org/10.1021/jo300214dopenalex-snapshot
Inflammation and Cancer: Chemical Approaches to Mechanisms, Imaging, and Treatment
inferred← citeshttps://doi.org/10.1021/jo701373fopenalex-snapshot
Synthesis of Six Epoxyketooctadecenoic Acid (EKODE) Isomers, Their Generation from Nonenzymatic Oxidation of Linoleic Acid, and Their Reactivity with Imidazole Nucleophiles
inferred← citeshttps://doi.org/10.1021/jo971239+openalex-snapshot
Structure of a Fluorescent Compound Formed from 4-Hydroxy-2-nonenal and N α -Hippuryllysine: A Model for Fluorophores Derived from Protein Modifications by Lipid Peroxidation
inferred← citeshttps://doi.org/10.1021/jo982523jopenalex-snapshot
Independent Synthesis, Solution Behavior, and Studies on the Mechanism of Formation of a Primary Amine-Derived Fluorophore Representing Cross-linking of Proteins by (E)-4-Hydroxy-2-nonenal
inferred← citeshttps://doi.org/10.1021/jp075349oopenalex-snapshot
Atmospheric Reaction of OH Radicals with 1,3-Butadiene and 4-Hydroxy-2-butenal
inferred← citeshttps://doi.org/10.1021/tx000007uopenalex-snapshot
HNE-Derived 2-Pentylpyrroles Are Generated during Oxidation of LDL, Are More Prevalent in Blood Plasma from Patients with Renal Disease or Atherosclerosis, and Are Present in Atherosclerotic Plaques
inferred← citeshttps://doi.org/10.1021/tx100228qopenalex-snapshot
Mass Spectrometric Characterization of Modifications to Angiotensin II by Lipid Peroxidation Products, 4-Oxo-2(E)-nonenal and 4-Hydroxy-2(E)-nonenal
inferred← citeshttps://doi.org/10.1021/tx300264xopenalex-snapshot
Small Molecule Activators of the Heat Shock Response: Chemical Properties, Molecular Targets, and Therapeutic Promise
inferred← citeshttps://doi.org/10.1021/tx5001046openalex-snapshot
Molecular Mechanisms of Aldehyde Toxicity: A Chemical Perspective
inferred← citeshttps://doi.org/10.1021/tx7000509openalex-snapshot
Enantioselective Oxidation oftrans-4-Hydroxy-2-Nonenal Is Aldehyde Dehydrogenase Isozyme and Mg2+Dependent
inferred← citeshttps://doi.org/10.1021/tx700111vopenalex-snapshot
Covalent Modification of Cytochrome c Exposed to trans,trans-2,4-Decadienal
inferred← citeshttps://doi.org/10.1021/tx8000303openalex-snapshot
Low-Density Lipoprotein Has an Enormous Capacity To Bind (E)-4-Hydroxynon-2-enal (HNE): Detection and Characterization of Lysyl and Histidyl Adducts Containing Multiple Molecules of HNE
inferred← citeshttps://doi.org/10.1021/tx800092gopenalex-snapshot
Formation of DNA−Protein Cross-Links Between γ-Hydroxypropanodeoxyguanosine and EcoRI
inferred← citeshttps://doi.org/10.1021/tx800316vopenalex-snapshot
A Novel 4-Oxo-2(E)-nonenal-Derived Modification to Angiotensin II: Oxidative Decarboxylation of N-Terminal Aspartic Acid
inferred← citeshttps://doi.org/10.1021/tx800320mopenalex-snapshot
Conformational Interconversion of the trans-4-Hydroxynonenal-Derived (6S,8R,11S) 1,N2-Deoxyguanosine Adduct When Mismatched with Deoxyadenosine in DNA
inferred← citeshttps://doi.org/10.1021/tx9000072openalex-snapshot
Mass Spectrometric Characterization of Protein Modification by the Products of Nonenzymatic Oxidation of Linoleic Acid
inferred← citeshttps://doi.org/10.1021/tx9000144openalex-snapshot
Covalent Cross-Linking of Glutathione and Carnosine to Proteins by 4-Oxo-2-nonenal
inferred← citeshttps://doi.org/10.1021/tx900147gopenalex-snapshot
Molecular Mechanisms of 4-Hydroxy-2-nonenal and Acrolein Toxicity: Nucleophilic Targets and Adduct Formation
inferred← citeshttps://doi.org/10.1021/tx900379aopenalex-snapshot
Mass Spectrometric Evidence for the Existence of Distinct Modifications of Different Proteins by 2(E),4(E)-Decadienal
inferred← citeshttps://doi.org/10.1021/tx960094jopenalex-snapshot
Immunochemical Evidence Supporting 2-Pentylpyrrole Formation on Proteins Exposed to 4-Hydroxy-2-nonenal
inferred← citeshttps://doi.org/10.1021/tx9701790openalex-snapshot
Reactions of 1-Methyl-2-phenylindole with Malondialdehyde and 4-Hydroxyalkenals. Analytical Applications to a Colorimetric Assay of Lipid Peroxidation
inferred← citeshttps://doi.org/10.1021/tx970180zopenalex-snapshot
Reactions of N-Methyl-2-phenylindole with Malondialdehyde and 4-Hydroxyalkenals. Mechanistic Aspects of the Colorimetric Assay of Lipid Peroxidation
inferred← citeshttps://doi.org/10.1038/nprot.2016.114openalex-snapshot
T-REX on-demand redox targeting in live cells
inferred← citeshttps://doi.org/10.1038/sj.bjp.0707395openalex-snapshot
Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors
inferred← citeshttps://doi.org/10.1039/c4cy00271gopenalex-snapshot
Copper–dienamine catalysis: γ-oxyamination of α,β-unsaturated aldehydes
inferred← citeshttps://doi.org/10.1039/c6pp00257aopenalex-snapshot
The effects of photodynamic treatment with new methylene blue N on the Candida albicans proteome
inferred← citeshttps://doi.org/10.1039/d1ra06872eopenalex-snapshot
Lipid oxidation and protein co-oxidation in ready-to-eat meat products as affected by temperature, antioxidant, and packaging material during 6 months of storage
inferred← citeshttps://doi.org/10.1042/bj3240001openalex-snapshot
Biochemistry and pathology of radical-mediated protein oxidation
inferred← citeshttps://doi.org/10.1046/j.1471-4159.1997.68052092.xopenalex-snapshot
4‐Hydroxynonenal‐Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease
inferred← citeshttps://doi.org/10.1046/j.1471-4159.1997.69031161.xopenalex-snapshot
The Lipid Peroxidation Product, 4‐Hydroxy‐2‐trans‐Nonenal, Alters the Conformation of Cortical Synaptosomal Membrane Proteins
inferred← citeshttps://doi.org/10.1046/j.1471-4159.1999.721617.xopenalex-snapshot
4‐Hydroxy‐2(E)‐Nonenal Inhibits CNS Mitochondrial Respiration at Multiple Sites
inferred← citeshttps://doi.org/10.1046/j.1471-4159.2000.0751234.xopenalex-snapshot
In Alzheimer's Disease, Heme Oxygenase Is Coincident with Alz50, an Epitope of τ Induced by 4‐Hydroxy‐2‐Nonenal Modification
inferred← citeshttps://doi.org/10.1046/j.1471-4159.2003.01628.xopenalex-snapshot
Mitochondrial oxidation of 4‐hydroxy‐2‐nonenal in rat cerebral cortex
inferred← citeshttps://doi.org/10.1073/pnas.2415039122openalex-snapshot
The unique reactivity of EKODE lipid peroxidation products allows in vivo detection of inflammation
inferred← citeshttps://doi.org/10.1073/pnas.95.2.510openalex-snapshot
Cardiac reperfusion injury: Aging, lipid peroxidation, and mitochondrial dysfunction
inferred← citeshttps://doi.org/10.1074/jbc.271.6.2892openalex-snapshot
Hydroxyalkenal Formation Induced by Advanced Glycosylation of Low Density Lipoprotein
inferred← citeshttps://doi.org/10.1074/jbc.272.36.22611openalex-snapshot
Metabolic Activation of trans-4-Hydroxy-2-nonenal, a Toxic Product of Membrane Lipid Peroxidation and Inhibitor of P450 Cytochromes
inferred← citeshttps://doi.org/10.1074/jbc.m101947200openalex-snapshot
Endogenous Formation of Protein Adducts with Carcinogenic Aldehydes
inferred← citeshttps://doi.org/10.1074/jbc.m110913200openalex-snapshot
High Molecular Weight Neurofilament Proteins Are Physiological Substrates of Adduction by the Lipid Peroxidation Product Hydroxynonenal
inferred← citeshttps://doi.org/10.1074/jbc.m210129200openalex-snapshot
Structural Basis of Protein-bound Endogenous Aldehydes
inferred← citeshttps://doi.org/10.1074/jbc.m608589200openalex-snapshot
Membrane-mediated Amyloidogenesis and the Promotion of Oxidative Lipid Damage by Amyloid β Proteins
inferred← citeshttps://doi.org/10.1074/jbc.m801725200openalex-snapshot
The Stereochemical Course of 4-Hydroxy-2-nonenal Metabolism by Glutathione S-Transferases
inferred← citeshttps://doi.org/10.1074/jbc.ra118.003469openalex-snapshot
Obesity-induced protein carbonylation in murine adipose tissue regulates the DNA-binding domain of nuclear zinc finger proteins
inferred← citeshttps://doi.org/10.1080/03602530600959508openalex-snapshot
Protein Adducts Generated from Products of Lipid Oxidation: Focus on HNE and ONE
inferred← citeshttps://doi.org/10.1080/03602530600969440openalex-snapshot
Carbonyl Reductases and Pluripotent Hydroxysteroid Dehydrogenases of the Short-chain Dehydrogenase/reductase Superfamily
inferred← citeshttps://doi.org/10.1080/10715760000300891openalex-snapshot
4-Hydroxynonenal, an end-product of lipid peroxidation, induces apoptosis in human leukemic T- and B-cell lines
inferred← citeshttps://doi.org/10.1080/13510002.1996.11747065openalex-snapshot
Lipid and lipoprotein oxidation: basic mechanisms and unresolved questions in vivo
inferred← citeshttps://doi.org/10.1080/15287390490425579openalex-snapshot
Green Tea Protection Against Age-Dependent Ethanol-Induced Oxidative Stress
inferred← citeshttps://doi.org/10.1080/15376510701623508openalex-snapshot
The Influence of L-Carnitine on Oxidative Modification of LDL In Vitro
inferred← citeshttps://doi.org/10.1089/ars.1999.1.3-255openalex-snapshot
4-Hydroxynonenal As a Biological Signal: Molecular Basis and Pathophysiological Implications
inferred← citeshttps://doi.org/10.1089/ars.2014.6166openalex-snapshot
Role of 4-Hydroxynonenal-Protein Adducts in Human Diseases
inferred← citeshttps://doi.org/10.1093/emboj/cdg412openalex-snapshot
A signalling role for 4‐hydroxy‐2‐nonenal in regulation of mitochondrial uncoupling
inferred← citeshttps://doi.org/10.1093/toxsci/kfm301openalex-snapshot
Molecular Mechanisms of the Conjugated α,β-Unsaturated Carbonyl Derivatives: Relevance to Neurotoxicity and Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1093/toxsci/kfn226openalex-snapshot
Synaptosomal Toxicity and Nucleophilic Targets of 4-Hydroxy-2-Nonenal
inferred← citeshttps://doi.org/10.1097/00001756-199707070-00036openalex-snapshot
4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau
inferred← citeshttps://doi.org/10.1111/j.1471-4159.2009.05883.xopenalex-snapshot
The essential role of ERK in 4‐oxo‐2‐nonenal‐mediated cytotoxicity in SH‐SY5Y human neuroblastoma cells
inferred← citeshttps://doi.org/10.1124/pr.59.2.1openalex-snapshot
Neurotoxicity and Metabolism of the Catecholamine-Derived 3,4-Dihydroxyphenylacetaldehyde and 3,4-Dihydroxyphenylglycolaldehyde: The Role of Aldehyde Dehydrogenase
inferred← citeshttps://doi.org/10.1149/2.0181610jesopenalex-snapshot
Redox Mechanism, Antioxidant Activity and Computational Studies of Triazole and Phenol Containing Schiff Bases
inferred← citeshttps://doi.org/10.1152/ajpendo.00508.2010openalex-snapshot
Signaling and cytotoxic functions of 4-hydroxyalkenals
inferred← citeshttps://doi.org/10.1159/000319943openalex-snapshot
Immunochemical Detection of 4-Hydroxy-2-Nonenal-Specific Epitopes
inferred← citeshttps://doi.org/10.1161/01.cir.97.11.1071openalex-snapshot
Induction of Rat Aortic Smooth Muscle Cell Growth by the Lipid Peroxidation Product 4-Hydroxy-2-Nonenal
inferred← citeshttps://doi.org/10.1161/atvbaha.113.300972openalex-snapshot
4-Hydroxy-2-Nonenal Enhances Tissue Factor Activity in Human Monocytic Cells via p38 Mitogen-Activated Protein Kinase Activation-Dependent Phosphatidylserine Exposure
inferred← citeshttps://doi.org/10.1167/iovs.07-0170openalex-snapshot
Oxidative Stress Is an Early Event in Hydrostatic Pressure–Induced Retinal Ganglion Cell Damage
inferred← citeshttps://doi.org/10.1179/135100007x162176openalex-snapshot
Mass spectrometric evidence for long-lived protein adducts of 4-oxo-2-nonenal
inferred← citeshttps://doi.org/10.1186/s12929-016-0312-xopenalex-snapshot
Aldehyde dehydrogenase 2 activation and coevolution of its εPKC-mediated phosphorylation sites
inferred← citeshttps://doi.org/10.1194/jlr.m076562openalex-snapshot
The sphingosine 1-phosphate breakdown product, (2E)-hexadecenal, forms protein adducts and glutathione conjugates in vitro
inferred← citeshttps://doi.org/10.1194/jlr.m200450-jlr200openalex-snapshot
Covalent binding of hydroxy-alkenals 4-HDDE, 4-HHE, and 4-HNE to ethanolamine phospholipid subclasses
inferred← citeshttps://doi.org/10.1194/jlr.m600340-jlr200openalex-snapshot
Evidence for in situ ethanolamine phospholipid adducts with hydroxy-alkenals
inferred← citeshttps://doi.org/10.1201/9781420045390.ch8openalex-snapshot
Inactivation and Inhibition of Alpha-Ketoglutarate Dehydrogenase
inferred← citeshttps://doi.org/10.1517/17425255.4.6.697openalex-snapshot
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily
inferred← citeshttps://doi.org/10.2174/0929867326666190624094813openalex-snapshot
The Disposal of Reactive Carbonyl Species through Carnosine Conjugation: What We Know Now
inferred← citeshttps://doi.org/10.25148/etd.fidc007036openalex-snapshot
An Investigation into the Adduct Forming Potential of Drugs of Abuse with Peptides and Proteins
inferred← citeshttps://doi.org/10.3109/03602539808996310openalex-snapshot
Reactive Oxygen-Mediated Protein Oxidation in Aging and Disease
inferred← citeshttps://doi.org/10.3109/09687688.2015.1023376openalex-snapshot
Protein “amyloid-like” networks at the phospholipid membrane formed by 4-hydroxy-2-nonenal-modified mitochondrial creatine kinase
inferred← citeshttps://doi.org/10.3109/10715762.2010.498477openalex-snapshot
Chemistry and biochemistry of lipid peroxidation products
inferred← citeshttps://doi.org/10.3109/10715762.2010.520014openalex-snapshot
Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease
inferred← citeshttps://doi.org/10.3109/10715762.2013.815348openalex-snapshot
Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation
inferred← citeshttps://doi.org/10.3109/10715762.2015.1036052openalex-snapshot
Aldehyde adducts generated during lipid peroxidation modification of proteins
inferred← citeshttps://doi.org/10.3109/10715762.2015.1094184openalex-snapshot
Reactions of electrophiles with nucleophilic thiolate sites: relevance to pathophysiological mechanisms and remediation
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