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Cellular Toxicity Associated with Exposure to Perfluorinated Carboxylates (PFCAs) and Their Metabolic Precursors
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/etc.141openalex-snapshot
Chronic toxicity of fluorotelomer acids to Daphnia magna and Chironomus dilutus
inferredcites →https://doi.org/10.1002/etc.211openalex-snapshot
Fate of fluorotelomer acids in a soil–water microcosm
inferredcites →https://doi.org/10.1002/tox.20396openalex-snapshot
Toxicity of perfluorooctane sulfonate and perfluorooctanoic acid to plants and aquatic invertebrates
inferredcites →https://doi.org/10.1007/978-0-387-73163-6openalex-snapshot
Reviews of Environmental Contamination and Toxicology
inferredcites →https://doi.org/10.1007/978-1-4614-1463-6openalex-snapshot
Reviews of Environmental Contamination and Toxicology
inferredcites →https://doi.org/10.1007/s10565-012-9211-4openalex-snapshot
Assessing the structure–activity relationships of fluorotelomer unsaturated acids and aldehydes with glutathione
inferredcites →https://doi.org/10.1016/0022-1139(94)03084-dopenalex-snapshot
Synthesis of 2H,2H-perfluoroalkyl and 2H-perfluoroalkenyl carboxylic acids and amides
inferredcites →https://doi.org/10.1016/j.cbi.2005.06.007openalex-snapshot
Metabolic products and pathways of fluorotelomer alcohols in isolated rat hepatocytes
inferredcites →https://doi.org/10.1016/j.cbi.2009.03.015openalex-snapshot
Kinetics of 8-2 fluorotelomer alcohol and its metabolites, and liver glutathione status following daily oral dosing for 45 days in male and female rats
inferredcites →https://doi.org/10.1016/j.cbi.2010.07.011openalex-snapshot
Molecular mechanisms of fluoride toxicity
inferredcites →https://doi.org/10.1016/j.chemosphere.2009.02.053openalex-snapshot
Estimated dietary exposure to fluorinated compounds from traditional foods among Inuit in Nunavut, Canada
inferredcites →https://doi.org/10.1016/j.etap.2011.05.011openalex-snapshot
Hydrophobicity-dependent QSARs to predict the toxicity of perfluorinated carboxylic acids and their mixtures
inferredcites →https://doi.org/10.1016/j.jchromb.2005.03.002openalex-snapshot
Quantitative determination of perfluorooctanoic acid in serum and plasma by liquid chromatography tandem mass spectrometry
inferredcites →https://doi.org/10.1016/j.reprotox.2011.04.001openalex-snapshot
Effects of per- and polyfluorinated compounds on adult rat testicular cells following in vitro exposure
inferredcites →https://doi.org/10.1016/j.reprotox.2011.08.004openalex-snapshot
Toxicological evaluation of ammonium perfluorobutyrate in rats: Twenty-eight-day and ninety-day oral gavage studies
inferredcites →https://doi.org/10.1016/j.tox.2011.06.012openalex-snapshot
Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes
inferredcites →https://doi.org/10.1016/j.tox.2011.11.005openalex-snapshot
8:2 fluorotelomer alcohol: A one-day nose-only inhalation toxicokinetic study in the Sprague-Dawley rat with application to risk assessment
inferredcites →https://doi.org/10.1016/s0040-4039(98)02029-2openalex-snapshot
Synthesis of Per(poly)fluoroalkyl aldehydes RF(CH2)nCHO
inferredcites →https://doi.org/10.1016/s0045-6535(02)00498-8openalex-snapshot
Fluoride toxicity to aquatic organisms: a review
inferredcites →https://doi.org/10.1021/ac701830sopenalex-snapshot
Sorbent-Impregnated Polyurethane Foam Disk for Passive Air Sampling of Volatile Fluorinated Chemicals
inferredcites →https://doi.org/10.1021/es001489zopenalex-snapshot
Compound-Specific, Quantitative Characterization of Organic Fluorochemicals in Biological Matrices
inferredcites →https://doi.org/10.1021/es034727+openalex-snapshot
Identification of Long-Chain Perfluorinated Acids in Biota from the Canadian Arctic
inferredcites →https://doi.org/10.1021/es051619+openalex-snapshot
Significant Residual Fluorinated Alcohols Present in Various Fluorinated Materials
inferredcites →https://doi.org/10.1021/es052067yopenalex-snapshot
Perfluorooctanesulfonate and Related Fluorochemicals in Human Blood Samples from China
inferredcites →https://doi.org/10.1021/es070126xopenalex-snapshot
Production of Perfluorinated Carboxylic Acids (PFCAs) from the Biotransformation of Polyfluoroalkyl Phosphate Surfactants (PAPS): Exploring Routes of Human Contamination
inferredcites →https://doi.org/10.1021/es070734copenalex-snapshot
Fluorotelomer Acids are More Toxic than Perfluorinated Acids
inferredcites →https://doi.org/10.1021/es100702aopenalex-snapshot
Elucidating the Pathways of Poly- and Perfluorinated Acid Formation in Rainbow Trout
inferredcites →https://doi.org/10.1021/es102384zopenalex-snapshot
Polyfluorinated Compounds in Residential and Nonresidential Indoor Air
inferredcites →https://doi.org/10.1021/es200167qopenalex-snapshot
A Pilot Survey of Legacy and Current Commercial Fluorinated Chemicals in Human Sera from United States Donors in 2009
inferredcites →https://doi.org/10.1021/es3008485openalex-snapshot
In Vitro Interactions of Biological Nucleophiles with Fluorotelomer Unsaturated Acids and Aldehydes: Fate and Consequences
inferredcites →https://doi.org/10.1021/es303760uopenalex-snapshot
Covalent Binding of Fluorotelomer Unsaturated Aldehydes (FTUALs) and Carboxylic Acids (FTUCAs) to Proteins
inferredcites →https://doi.org/10.1021/es800631nopenalex-snapshot
Perfluorinated Compounds and Total and Extractable Organic Fluorine in Human Blood Samples from China
inferredcites →https://doi.org/10.1021/es802827uopenalex-snapshot
Time Trends and the Influence of Age and Gender on Serum Concentrations of Perfluorinated Compounds in Archived Human Samples
inferredcites →https://doi.org/10.1021/jf9014125openalex-snapshot
Historic Dietary Exposure to Perfluorooctane Sulfonate, Perfluorinated Carboxylates, and Fluorotelomer Unsaturated Carboxylates from the Consumption of Store-Bought and Restaurant Foods for the Canadian Population
inferredcites →https://doi.org/10.1021/tx00046a009openalex-snapshot
Direct Characterization of Protein Adducts of the Lipid Peroxidation Product 4-Hydroxy-2-nonenal Using Electrospray Mass Spectrometry
inferredcites →https://doi.org/10.1021/tx034170bopenalex-snapshot
Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development
inferredcites →https://doi.org/10.1021/tx060062oopenalex-snapshot
Future of ToxicologyMetabolic Activation and Drug Design: Challenges and Opportunities in Chemical Toxicology
inferredcites →https://doi.org/10.1021/tx700235topenalex-snapshot
Protein Damage by Reactive Electrophiles: Targets and Consequences
inferredcites →https://doi.org/10.1039/b701417aopenalex-snapshot
Analysis of per- and polyfluorinated alkyl substances in air samples from Northwest Europe
inferredcites →https://doi.org/10.1073/pnas.90.11.5123openalex-snapshot
Simian virus 40 large tumor antigen-immortalized normal human liver epithelial cells express hepatocyte characteristics and metabolize chemical carcinogens.
inferredcites →https://doi.org/10.1080/02652030500183474openalex-snapshot
Perfluorochemicals: Potential sources of and migration from food packaging
inferredcites →https://doi.org/10.1080/02652030701513784openalex-snapshot
Migration of fluorochemical paper additives from food-contact paper into foods and food simulants
inferredcites →https://doi.org/10.1093/toxsci/kfj160openalex-snapshot
Absorption, Distribution, Metabolism, and Elimination of 8-2 Fluorotelomer Alcohol in the Rat
inferredcites →https://doi.org/10.1093/toxsci/kfm128openalex-snapshot
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
inferredcites →https://doi.org/10.1093/toxsci/kfm230openalex-snapshot
In Vitro Metabolism of 8-2 Fluorotelomer Alcohol: Interspecies Comparisons and Metabolic Pathway Refinement
inferredcites →https://doi.org/10.1093/toxsci/kfm270openalex-snapshot
Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of Action
inferredcites →https://doi.org/10.1093/toxsci/kfp093openalex-snapshot
Structure-Activity Relationships and Human Relevance for Perfluoroalkyl Acid–Induced Transcriptional Activation of Peroxisome Proliferation in Liver Cell Cultures
inferredcites →https://doi.org/10.1124/dmd.110.035873openalex-snapshot
Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
inferredcites →https://doi.org/10.1146/annurev.pharmtox.37.1.91openalex-snapshot
PROTEIN TARGETS OF XENOBIOTIC REACTIVE INTERMEDIATES
inferredcites →https://doi.org/10.1248/bpb.29.1952openalex-snapshot
Responses of the Liver to Perfluorinated Fatty Acids with Different Carbon Chain Length in Male and Female Mice:In Relation to Induction of Hepatomegaly, Peroxisomal .BETA.-Oxidation and Microsomal 1-Acylglycerophosphocholine Acyltransferase
inferredcites →https://doi.org/10.1265/ehpm.12.217openalex-snapshot
Negative results ofumu genotoxicity test of fluorotelomer alcohols and perfluorinated alkyl acids
inferredcites →https://doi.org/10.1289/ehp.10009openalex-snapshot
Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers
inferredcites →https://doi.org/10.1289/ehp.1002409openalex-snapshot
Exploring Indirect Sources of Human Exposure to Perfluoroalkyl Carboxylates (PFCAs): Evaluating Uptake, Elimination, and Biotransformation of Polyfluoroalkyl Phosphate Esters (PAPs) in the Rat
inferredcites →https://doi.org/10.1289/ehp.6316openalex-snapshot
Perfluorooctanesulfonate and other fluorochemicals in the serum of American Red Cross adult blood donors.
inferredcites →https://doi.org/10.1289/ehp.961041159openalex-snapshot
Phenylguanine Found in Urine after Benzene Exposure
inferredcites →https://doi.org/10.1897/07-459openalex-snapshot
TOXIC EFFECT OF SERIAL PERFLUOROSULFONIC AND PERFLUOROCARBOXYLIC ACIDS ON THE MEMBRANE SYSTEM OF A FRESHWATER ALGA MEASURED BY FLOW CYTOMETRY
inferredcites →https://doi.org/10.1897/07-459.1openalex-snapshot
Toxic effect of serial perfluorosulfonic and perfluorocarboxylic acids on the membrane system of a freshwater alga measured by flow cytometry
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4679623openalex-extracted
Determination of Perfluorinated Compounds (PFAS) in Certain Food Stuffs According to Newly Established EU Legislation
inferred← citeshttps://doi.org/10.1002/art.42779openalex-snapshot
Screening of Environmental Chemicals to Characterize Exposures in Participants With Systemic Lupus Erythematosus
inferred← citeshttps://doi.org/10.1002/cbic.202500905openalex-snapshot
Human Intestinal Microbiota Composition Shapes Model Polyfluoroalkyl Substance Biotransformation
inferred← citeshttps://doi.org/10.1002/etc.2663openalex-snapshot
Fate and effects of poly- and perfluoroalkyl substances in the aquatic environment: A review
inferred← citeshttps://doi.org/10.1002/etc.5060openalex-snapshot
Uptake, Tissue Distribution, and Elimination of 8:2 Polyfluoroalkyl Phosphate Diesters in Mytilus galloprovincialis
inferred← citeshttps://doi.org/10.1007/978-1-4939-2074-7_4openalex-snapshot
Immortalized Human Hepatic Cell Lines for In Vitro Testing and Research Purposes
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Role of Perfluoroalkyl Substances as EDCs in Metabolic Disorders
inferred← citeshttps://doi.org/10.1007/s00204-018-2266-0openalex-snapshot
Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells
inferred← citeshttps://doi.org/10.1007/s11356-018-3070-3openalex-snapshot
Plant uptake and translocation of perfluoroalkyl acids in a wheat–soil system
inferred← citeshttps://doi.org/10.1007/s12161-024-02603-yopenalex-snapshot
Determination of Perfluorinated Substances (PFAS) Using LC-ORBITRAP-MS in Certain foodstuffs of Animal Origin According to newly established EU legislation
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Liver Tissue Engineering
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High throughput online solid phase extraction-ultra high performance liquid chromatography-tandem mass spectrometry method for polyfluoroalkyl phosphate esters, perfluoroalkyl phosphonates, and other perfluoroalkyl substances in human serum, plasma, and whole blood
inferred← citeshttps://doi.org/10.1016/j.aquatox.2026.107966openalex-snapshot
PFAS exposure suppresses leaf litter decomposition in a stream ecosystem
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2015.10.063openalex-snapshot
Human placental transfer of perfluoroalkyl acid precursors: Levels and profiles in paired maternal and cord serum
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.119084openalex-snapshot
Retention and transport of PFAS precursor 6:2 FTS in heterogeneous variably saturated porous media
inferred← citeshttps://doi.org/10.1016/j.envint.2024.108540openalex-snapshot
Unveiling per- and polyfluoroalkyl substance contamination in Chinese paper products and assessing their exposure risk
inferred← citeshttps://doi.org/10.1016/j.envpol.2019.113513openalex-snapshot
Biotransformation of 6:2 fluorotelomer alcohol by the whole soybean (Glycine max L. Merrill) seedlings
inferred← citeshttps://doi.org/10.1016/j.envpol.2019.113835openalex-snapshot
Formation of perfluorocarboxylic acids from 6:2 fluorotelomer sulfonate (6:2 FTS) in landfill leachate: Role of microbial communities
inferred← citeshttps://doi.org/10.1016/j.envpol.2020.115908openalex-snapshot
Biotransformation of perfluoroalkyl acid precursors from various environmental systems: advances and perspectives
inferred← citeshttps://doi.org/10.1016/j.envpol.2025.127357openalex-snapshot
Unraveling the reproductive toxicity mechanisms of emerging environmental contaminants 6:2 and 8:2 diPAPs in male mice: an integrated transcriptome-metabolome investigation
inferred← citeshttps://doi.org/10.1016/j.envres.2020.110243openalex-snapshot
Emerging and legacy per- and polyfluoroalkyl substances in house dust from South China: Contamination status and human exposure assessment
inferred← citeshttps://doi.org/10.1016/j.eti.2020.101198openalex-snapshot
Perfluoroalkyl substances associations with morphometric health indices in three fish species from differentially contaminated water bodies in Southeastern Brazil
inferred← citeshttps://doi.org/10.1016/j.fluid.2026.114821openalex-snapshot
Methoxybenzene-based hydrogen bond acceptors for constructing functional deep eutectic solvents for fluorotelomer alcohol extraction: A combined experimental and theoretical study
inferred← citeshttps://doi.org/10.1016/j.jenvman.2021.113336openalex-snapshot
Detection and removal of poly and perfluoroalkyl polluting substances for sustainable environment
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2016.08.036openalex-snapshot
Biotransformation of 6:2 polyfluoroalkyl phosphates (6:2 PAPs): Effects of degradative bacteria and co-substrates
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2023.133018openalex-snapshot
Polyfluoroalkyl phosphate esters (PAPs) as PFAS substitutes and precursors: An overview
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.135269openalex-snapshot
Comparative toxicity assessment of alternative versus legacy PFAS: Implications for two primary trophic levels in freshwater ecosystems
inferred← citeshttps://doi.org/10.1016/j.jhep.2014.05.046openalex-snapshot
Strategies for immortalization of primary hepatocytes
inferred← citeshttps://doi.org/10.1016/j.microc.2023.109884openalex-snapshot
Development and application of a new deep eutectic solvent based magnetic metal–organic framework adsorbent for the detection of fluorotelomer alcohols in edible oils
inferred← citeshttps://doi.org/10.1016/j.redox.2020.101580openalex-snapshot
Role of non-coding-RNAs in response to environmental stressors and consequences on human health
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2017.07.241openalex-snapshot
Biotransformation of 8:2 polyfluoroalkyl phosphate diester in gilthead bream (Sparus aurata)
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2017.08.075openalex-snapshot
Effects of microbial activity on perfluorinated carboxylic acids (PFCAs) generation during aerobic biotransformation of fluorotelomer alcohols in activated sludge
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2022.157255openalex-snapshot
A review of omics-based PFAS exposure studies reveals common biochemical response pathways
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2025.180727openalex-snapshot
Urban possums as sentinels for environmental contamination: First evidence of PFAS in Australian marsupials
inferred← citeshttps://doi.org/10.1016/j.talanta.2016.02.022openalex-snapshot
Fast and simple determination of perfluorinated compounds and their potential precursors in different packaging materials
inferred← citeshttps://doi.org/10.1016/j.tox.2016.11.011openalex-snapshot
Is there a human health risk associated with indirect exposure to perfluoroalkyl carboxylates (PFCAs)?
inferred← citeshttps://doi.org/10.1016/j.toxrep.2019.08.009openalex-snapshot
Toxicokinetics of 8:2 fluorotelomer alcohol (8:2-FTOH) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration
inferred← citeshttps://doi.org/10.1016/j.trac.2019.02.032openalex-snapshot
Unique analytical considerations for laboratory studies identifying metabolic products of per- and polyfluoroalkyl substances (PFASs)
inferred← citeshttps://doi.org/10.1021/acs.est.1c03773openalex-snapshot
A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to Eggs in an Arctic Seabird
inferred← citeshttps://doi.org/10.1021/acs.est.2c00254openalex-snapshot
Widening the Lens on PFASs: Direct Human Exposure to Perfluoroalkyl Acid Precursors (pre-PFAAs)
inferred← citeshttps://doi.org/10.1021/acs.est.5b00679openalex-snapshot
World-Wide Indoor Exposure to Polyfluoroalkyl Phosphate Esters (PAPs) and other PFASs in Household Dust
inferred← citeshttps://doi.org/10.1021/acs.estlett.1c00049openalex-snapshot
Response to “Comment on Scientific Basis for Managing PFAS as a Chemical Class”
inferred← citeshttps://doi.org/10.1021/acs.estlett.2c00926openalex-snapshot
Per- and Polyfluoroalkyl Substances in Canadian Fast Food Packaging
inferred← citeshttps://doi.org/10.1021/acsestwater.3c00464openalex-snapshot
Controllable Generation of Sulfate and Hydroxyl Radicals to Efficiently Degrade Perfluorooctanoic Acid in Cathode-Dominated Electrochemical Process
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Advancing Toxicity Predictions: A Review on in Vitro to in Vivo Extrapolation in Next-Generation Risk Assessment
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Nanoscale fletching of liquid-like polydimethylsiloxane with single perfluorocarbons enables sustainable oil-repellency
inferred← citeshttps://doi.org/10.1039/c5ra04945hopenalex-snapshot
Controlling electrodeposited conducting polymer nanostructures with the number and the length of fluorinated chains for adjusting superhydrophobic properties and adhesion
inferred← citeshttps://doi.org/10.1039/c6em00071aopenalex-snapshot
Biotransformation of 8:2 fluorotelomer alcohol by recombinant human cytochrome P450s, human liver microsomes and human liver cytosol
inferred← citeshttps://doi.org/10.1039/d0em00147copenalex-snapshot
Strategies for grouping per- and polyfluoroalkyl substances (PFAS) to protect human and environmental health
inferred← citeshttps://doi.org/10.1039/d1em00307kopenalex-snapshot
Emerging investigator series: human CYP2A6 catalyzes the oxidation of 6:2 fluorotelomer alcohol
inferred← citeshttps://doi.org/10.1039/d2em00225fopenalex-snapshot
The human fecal microbiome contributes to the biotransformation of the PFAS surfactant 8:2 monosubstituted polyfluoroalkyl phosphate ester
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Chemical food contaminants during food processing: sources and control
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The Role of MicroRNAs in Environmental Risk Factors, Noise-Induced Hearing Loss, and Mental Stress
inferred← citeshttps://doi.org/10.1101/2024.01.26.577438openalex-snapshot
Transcriptomics effects of per- and polyfluorinated alkyl substances in differentiated neuronal cells
inferred← citeshttps://doi.org/10.1289/ehp7431openalex-snapshot
Regulating PFAS as a Chemical Class under the California Safer Consumer Products Program
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3837067/v1openalex-snapshot
Determination of Perfluorinated Substances (Pfas) in Certain Foodstuffs According to Newly Established Eu Legislation
inferred← citeshttps://doi.org/10.22215/etd/2021-14487openalex-snapshot
The Metabolism of 6:2 Fluorotelomer Alcohol by CYP 2A6
inferred← citeshttps://doi.org/10.25148/etd.fidc008899openalex-snapshot
Advanced Oxidation Processes for the Remediation of Problematic Organophosphorus Compounds and Perfluoroalkyl Substances
inferred← citeshttps://doi.org/10.2903/j.efsa.2020.6223openalex-snapshot
Risk to human health related to the presence of perfluoroalkyl substances in food
inferred← citeshttps://doi.org/10.3390/ijerph17010100openalex-snapshot
Cost-Effective Detection of Perfluoroalkyl Carboxylic Acids with Gas Chromatography: Optimization of Derivatization Approaches and Method Validation
inferred← citeshttps://doi.org/10.3390/pr13124032openalex-snapshot
Confronting Novel Alternatives of Per- and Polyfluoroalkyl Substances: From the Exposure Pathway to the Health Risk Estimation
inferred← citeshttps://doi.org/10.3390/toxics11050446openalex-snapshot
A Review: Per- and Polyfluoroalkyl Substances—Biological Degradation
inferred← citeshttps://doi.org/10.70675/e97ccda4z438dz4cddzb54cz12df5cf693edopenalex-snapshot
Maternal transfer and physiological consequences of per- and polyfluoroalkyl substances in seabird eggs
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