On the public citation graph

Scutellarin protects against Aβ-induced learning and memory deficits in rats: involvement of nicotinic acetylcholine receptors and cholinesterase

https://doi.org/10.1038/aps.2011.115

0 signed · 83 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ana.410220206openalex-snapshot

Cholinesterases within neurofibrillary tangles related to age and Alzheimer's disease

inferredcites →https://doi.org/10.1002/jnr.10391openalex-snapshot

In vivo conversion of racemized β‐amyloid ([ D ‐Ser26]Aβ1–40) to truncated and toxic fragments ([ D ‐Ser26]Aβ25–35/40) and fragment presence in the brains of Alzheimer's patients

inferredcites →https://doi.org/10.1002/jnr.21463openalex-snapshot

Decreased nicotinic receptors and cognitive deficit in rats intracerebroventricularly injected with beta‐amyloid peptide(1‐42) and fed a high‐cholesterol diet

inferredcites →https://doi.org/10.1007/bf00307630openalex-snapshot

Senile plaques: staining for acetylcholinesterase and A4 protein: a comparative study in the hippocampus and entorhinal cortex

inferredcites →https://doi.org/10.1007/s00702-008-0022-yopenalex-snapshot

Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis

inferredcites →https://doi.org/10.1007/s007020100017openalex-snapshot

Suppressed expression of nicotinic acetylcholine receptors by nanomolar β-amyloid peptides in PC12 cells

inferredcites →https://doi.org/10.1016/0006-2952(61)90145-9openalex-snapshot

A new and rapid colorimetric determination of acetylcholinesterase activity

inferredcites →https://doi.org/10.1016/0165-0270(84)90007-4openalex-snapshot

Developments of a water-maze procedure for studying spatial learning in the rat

inferredcites →https://doi.org/10.1016/b978-0-12-547620-1.50003-5openalex-snapshot

WITHDRAWN: Dedication

inferredcites →https://doi.org/10.1016/c2009-0-63235-9openalex-snapshot

The Rat Brain in Stereotaxic Coordinates

inferredcites →https://doi.org/10.1016/j.bbr.2004.04.012openalex-snapshot

β-Amyloid (1–42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex

inferredcites →https://doi.org/10.1016/j.ejphar.2003.08.026openalex-snapshot

Amnesia induced by β-amyloid fragments is counteracted by cannabinoid CB1 receptor blockade

inferredcites →https://doi.org/10.1016/j.febslet.2009.11.036openalex-snapshot

Neuronal nicotinic acetylcholine receptor–cholesterol crosstalk in Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.lfs.2003.09.074openalex-snapshot

Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin

inferredcites →https://doi.org/10.1016/j.neuint.2010.08.001openalex-snapshot

Amyloid precursor protein gene mutated at Swedish 670/671 sites in vitro induces changed expression of nicotinic acetylcholine receptors and neurotoxicity

inferredcites →https://doi.org/10.1016/s0006-3223(00)01116-1openalex-snapshot

Nicotinic receptor abnormalities in Alzheimer’s disease

inferredcites →https://doi.org/10.1016/s0006-8993(02)03571-0openalex-snapshot

Selective changes in the levels of nicotinic acetylcholine receptor protein and of corresponding mRNA species in the brains of patients with Parkinson’s disease

inferredcites →https://doi.org/10.1016/s0026-895x(25)13162-3openalex-snapshot

Commonly occurring plant flavonoids have estrogenic activity.

inferredcites →https://doi.org/10.1016/s0091-3057(03)00128-xopenalex-snapshot

Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function

inferredcites →https://doi.org/10.1016/s0166-2236(98)01361-7openalex-snapshot

Acetylcholine in mind: a neurotransmitter correlate of consciousness?

inferredcites →https://doi.org/10.1016/s0197-4580(02)00230-0openalex-snapshot

Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex

inferredcites →https://doi.org/10.1016/s0301-0082(99)00045-3openalex-snapshot

Neuronal nicotinic receptors in the human brain

inferredcites →https://doi.org/10.1021/jf051985copenalex-snapshot

Effects of Naturally Occurring Compounds on Fibril Formation and Oxidative Stress of β-Amyloid

inferredcites →https://doi.org/10.1021/jf063299zopenalex-snapshot

Flavonoids Possess Neuroprotective Effects on Cultured Pheochromocytoma PC12 Cells: A Comparison of Different Flavonoids in Activating Estrogenic Effect and in Preventing β-Amyloid-Induced Cell Death

inferredcites →https://doi.org/10.1038/nrd2314openalex-snapshot

Therapies for Alzheimer's disease

inferredcites →https://doi.org/10.1046/j.1471-4159.2000.0740237.xopenalex-snapshot

Decreased Protein Levels of Nicotinic Receptor Subunits in the Hippocampus and Temporal Cortex of Patients with Alzheimer’s Disease

inferredcites →https://doi.org/10.1055/s-0028-1088368openalex-snapshot

Protective Effects of Scutellarin Against Cerebral Ischemia in Rats: Evidence for Inhibition of the Apoptosis-Inducing Factor Pathway

inferredcites →https://doi.org/10.1055/s-0029-1185776openalex-snapshot

Estrogenic and Neuroprotective Properties of Scutellarin fromErigeron breviscapus: A Drug against Postmenopausal Symptoms and Alzheimer's Disease

inferredcites →https://doi.org/10.1074/jbc.m006406200openalex-snapshot

The Neuroprotective Effects of Phytoestrogens on Amyloid β Protein-induced Toxicity Are Mediated by Abrogating the Activation of Caspase Cascade in Rat Cortical Neurons

inferredcites →https://doi.org/10.1097/fjc.0b013e3180cbd0e7openalex-snapshot

Protective Effects of Scutellarin and Breviscapine on Brain and Heart Ischemia in Rats

inferredcites →https://doi.org/10.1101/lm.69204openalex-snapshot

The Cholinergic Lesion of Alzheimer's Disease: Pivotal Factor or Side Show?

inferredcites →https://doi.org/10.1111/j.1745-7254.2007.00502.xopenalex-snapshot

Effects of scutellarin on PKC? in PC12 cell injury induced by oxygen and glucose deprivation

inferredcites →https://doi.org/10.1124/jpet.105.098640openalex-snapshot

Effects of a Novel Cognitive Enhancer, Spiro[imidazo-[1,2-a]pyridine-3,2-indan]-2(3 H)-one (ZSET1446), on Learning Impairments Induced by Amyloid-β1–40 in the Rat

inferredcites →https://doi.org/10.1124/pr.108.000562openalex-snapshot

Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer’s Disease and Amyloid Neuroprotection

inferredcites →https://doi.org/10.1146/annurev.pharmtox.47.120505.105214openalex-snapshot

Nicotinic Acetylcholine Receptors and Nicotinic Cholinergic Mechanisms of the Central Nervous System

inferredcites →https://doi.org/10.1196/annals.1254.007openalex-snapshot

Nicotinic Acetylcholine Receptors of Muscles and Nerves

inferredcites →https://doi.org/10.1212/wnl.43.2.301openalex-snapshot

Long‐term and high‐dose piracetam treatment of Alzheimer's disease

inferredcites →https://doi.org/10.1212/wnl.54.2.295openalex-snapshot

Estrogen for Alzheimer’s disease in women

inferredcites →https://doi.org/10.1248/bpb.29.1880openalex-snapshot

Protective Effects of Breviscapine on Ischemic Vascular Dementia in Rats

inferredcites →https://doi.org/10.1358/dot.2004.40.8.850473openalex-snapshot

Butyrylcholinesterase, cholinergic neurotransmission and the pathology of Alzheimer's disease

inferredcites →https://doi.org/10.1385/jmn:30:1:19openalex-snapshot

Ispronicline: A Novel α4β2 Nicotinic Acetylcholine Receptor-Selective Agonist With Cognition-Enhancing and Neuroprotective Properties

inferredcites →https://doi.org/10.14712/18059694.2018.95openalex-snapshot

Acetylcholinesterase and Butyrylcholinesterase – Important Enzymes of Human Body

inferredcites →https://doi.org/10.2174/138955705774329546openalex-snapshot

New Anti-Alzheimer Drugs from Biodiversity: The Role of the Natural Acetylcholinesterase Inhibitors

inferredcites →https://doi.org/10.3233/jad-2010-1283openalex-snapshot

Cholinesterase Activity and mRNA Level of Nicotinic Acetylcholine Receptors (α4 and β2 Subunits) in Blood of Elderly Chinese Diagnosed as Alzheimer's Disease

inferredcites →https://doi.org/10.3389/fnagi.2010.00008openalex-snapshot

Intracellular accumulation of amyloid-beta – a predictor for synaptic dysfunction and neuron loss in Alzheimer’s disease

inferredcites →https://doi.org/10.3389/neuro.24.003.2010openalex-snapshot

Oxidative stress mediates the pathogenic effect of different Alzheimer’s disease risk factors

inferredcites →https://doi.org/10.55782/ane-2004-1495openalex-snapshot

Alzheimer's disease and acetylcholine receptors

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4702812openalex-extracted

HSPA8 and 3,4,5-Tricaffeoylquinic Acid May Be Essential Hub Genes and Active Components for the Treatment of Alzheimer's Disease with Erigeron Breviscapus (Vant.) Hand-Mazz by Regulating Ferroptosis: A Study Based on WGCNA, Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations

inferred← citeshttps://doi.org/10.1007/978-3-030-94753-8_8-1openalex-snapshot

Scutellarin: Bioactivities, Pharmacology, and Development as Promising Therapeutic Agents and Nutraceuticals

inferred← citeshttps://doi.org/10.1007/s00702-017-1797-5openalex-snapshot

Neurotrophic function of phytochemicals for neuroprotection in aging and neurodegenerative disorders: modulation of intracellular signaling and gene expression

inferred← citeshttps://doi.org/10.1007/s12017-016-8394-xopenalex-snapshot

Scutellarin as a Potential Therapeutic Agent for Microglia-Mediated Neuroinflammation in Cerebral Ischemia

inferred← citeshttps://doi.org/10.1007/s12668-025-02386-4openalex-snapshot

Development and Fabrication of Mesoporous Silica Nanoparticle Loaded in Situ Nasal Gel of Scutellarin for Alzheimer’s Disease

inferred← citeshttps://doi.org/10.1016/j.bioorg.2020.103980openalex-snapshot

Synthesis, pharmacological evaluation and mechanistic study of scutellarin methyl ester -4′-dipeptide conjugates for the treatment of hypoxic-ischemic encephalopathy (HIE) in rat pups

inferred← citeshttps://doi.org/10.1016/j.etp.2012.05.003openalex-snapshot

The neurotoxicity of β-amyloid peptide toward rat brain is associated with enhanced oxidative stress, inflammation and apoptosis, all of which can be attenuated by scutellarin

inferred← citeshttps://doi.org/10.1016/j.intimp.2017.11.033openalex-snapshot

Scutellarin alleviates lipopolysaccharide-induced cognitive deficits in the rat: Insights into underlying mechanisms

inferred← citeshttps://doi.org/10.1016/j.intimp.2020.106943openalex-snapshot

Scutellarin protects against lipopolysaccharide-induced behavioral deficits by inhibiting neuroinflammation and microglia activation in rats

inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.138698openalex-snapshot

Integrated bioinformatics, network pharmacology, molecular docking, and molecular dynamics simulation to explore the potential pharmacological mechanism of Erigeron breviscapus (Vant.) Hand-Mazz regulating ferroptosis for the treatment of Alzheimer's disease

inferred← citeshttps://doi.org/10.1016/j.neuint.2016.04.007openalex-snapshot

Scutellarin promotes microglia-mediated astrogliosis coupled with improved behavioral function in cerebral ischemia

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2015.04.017openalex-snapshot

Selective activation of α7 nicotinic acetylcholine receptor by PHA-543613 improves Aβ25–35-mediated cognitive deficits in mice

inferred← citeshttps://doi.org/10.1016/j.pharmthera.2018.05.006openalex-snapshot

Clinical benefits and pharmacology of scutellarin: A comprehensive review

inferred← citeshttps://doi.org/10.1016/j.tice.2021.101624openalex-snapshot

Metanil yellow promotes oxidative stress, astrogliosis, and apoptosis in the cerebellar cortex of adult male rat with possible protective effect of scutellarin: A histological and immunohistochemical study

inferred← citeshttps://doi.org/10.1016/j.yexcr.2019.111546openalex-snapshot

Effect of α7nAChR on learning and memory dysfunction in a rat model of diffuse axonal injury

inferred← citeshttps://doi.org/10.1039/c9fo00058eopenalex-snapshot

Essential oil of Schisandra chinensis ameliorates cognitive decline in mice by alleviating inflammation

inferred← citeshttps://doi.org/10.1042/bcj20190705openalex-snapshot

Scutellarin inhibits the uninduced and metal-induced aggregation of α-Synuclein and disaggregates preformed fibrils: implications for Parkinson's disease

inferred← citeshttps://doi.org/10.1111/cns.70069openalex-snapshot

Alterations in Neuronal Nicotinic Acetylcholine Receptors in the Pathogenesis of Various Cognitive Impairments

inferred← citeshttps://doi.org/10.1142/s0192415x18500167openalex-snapshot

Pharmacological Effects of Scutellarin, An Active Component of GenusScutellariaandErigeron: A Systematic Review

inferred← citeshttps://doi.org/10.1142/s0192415x18500635openalex-snapshot

Scutellarin Ameliorates Learning and Memory Deficit via Suppressing β-Amyloid Formation and Microglial Activation in Rats with Chronic Cerebral Hypoperfusion

inferred← citeshttps://doi.org/10.1142/s0192415x21500312openalex-snapshot

Effect of Sutellarin on Neurogenesis in Neonatal Hypoxia–Ischemia Rat Model: Potential Mechanisms of Action

inferred← citeshttps://doi.org/10.1155/2013/507091openalex-snapshot

Functional Recovery after Scutellarin Treatment in Transient Cerebral Ischemic Rats: A Pilot Study with18F-Fluorodeoxyglucose MicroPET

inferred← citeshttps://doi.org/10.1155/2021/8820406openalex-snapshot

[Retracted] Natural Products for Neurodegeneration: Regulating Neurotrophic Signals

inferred← citeshttps://doi.org/10.1186/s13020-021-00517-zopenalex-snapshot

Scutellarin ameliorates neonatal hypoxic-ischemic encephalopathy associated with GAP43-dependent signaling pathway

inferred← citeshttps://doi.org/10.14670/hh-18-239openalex-snapshot

Microglia mediated neuroinflammation - signaling regulation and therapeutic considerations with special reference to some natural compounds.

inferred← citeshttps://doi.org/10.2174/0118746098373086251201095903openalex-snapshot

Recent Alzheimer’s Research Targets Amyloid-β with Novel Phytochemicals and Pharmacological Strategies for Therapy

inferred← citeshttps://doi.org/10.2174/1389200221666201217093255openalex-snapshot

Metabolism and Pharmacological Mechanisms of Active Ingredients in Erigeron breviscapus

inferred← citeshttps://doi.org/10.3389/fphar.2019.01035openalex-snapshot

Xanthoceraside Could Ameliorate Alzheimer’s Disease Symptoms of Rats by Affecting the Gut Microbiota Composition and Modulating the Endogenous Metabolite Levels

inferred← citeshttps://doi.org/10.3389/fphar.2022.877872openalex-snapshot

Erigeron breviscapus (Vant.) Hand-Mazz.: A Promising Natural Neuroprotective Agent for Alzheimer’s Disease

inferred← citeshttps://doi.org/10.3389/fphar.2024.1470879openalex-snapshot

Scutellarin: pharmacological effects and therapeutic mechanisms in chronic diseases

inferred← citeshttps://doi.org/10.3389/fphar.2026.1707688openalex-snapshot

Multi-target intervention mechanisms and prospects of the traditional Chinese medicine Scutellaria baicalensis georgi in Alzheimer’s disease

inferred← citeshttps://doi.org/10.3390/molecules19055748openalex-snapshot

In Vitro Inhibitory Effects of Scutellarin on Six Human/Rat Cytochrome P450 Enzymes and P-glycoprotein

inferred← citeshttps://doi.org/10.3390/molecules23040869openalex-snapshot

Scutellarin Mitigates Aβ-Induced Neurotoxicity and Improves Behavior Impairments in AD Mice

inferred← citeshttps://doi.org/10.3969/j.issn.1673-5374.2012.15.002openalex-snapshot

Wendan decoction improves learning and memory deficits in a rat model of schizophrenia.

inferred← citeshttps://doi.org/10.6084/m9.figshare.16829326openalex-snapshot

Additional file 1 of Scutellarin ameliorates neonatal hypoxic-ischemic encephalopathy associated with GAP43-dependent signaling pathway

inferred← citeshttps://doi.org/10.61958/ndtj4325openalex-snapshot

Scutellarin promotes neuronal function repair in oxygen-glucose deprivation neuronal model by regulating netrin-1 and associated with 3-kinase and protein kinase B

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.