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Jmjd3 is essential for the epigenetic modulation of microglia phenotypes in the immune pathogenesis of Parkinson’s disease

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1 of the 44 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1523/jneurosci.3878-11.2011 (notice 2013-12-11).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archneur.64.9.1242openalex-snapshot
The Relationship of Parkinson Disease With Aging
inferredcites →https://doi.org/10.1002/glia.20468openalex-snapshot
Microglia derived from aging mice exhibit an altered inflammatory profile
inferredcites →https://doi.org/10.1002/jnr.20315openalex-snapshot
(−)‐Epigallocatechin gallate inhibits lipopolysaccharide‐induced microglial activation and protects against inflammation‐mediated dopaminergic neuronal injury
inferredcites →https://doi.org/10.1002/mds.10332openalex-snapshot
Pathogenic role of glial cells in Parkinson's disease
inferredcites →https://doi.org/10.1002/syn.20768openalex-snapshot
Hippocampal epigenetic modification at the doublecortin gene is involved in the impairment of neurogenesis with aging
inferredcites →https://doi.org/10.1007/s00401-003-0766-2openalex-snapshot
Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains
inferredcites →https://doi.org/10.1007/s004010050792openalex-snapshot
Enlarged and phagocytic, but not primed, interleukin-1α-immunoreactive microglia increase with age in normal human brain
inferredcites →https://doi.org/10.1007/s11481-009-9164-4openalex-snapshot
Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain
inferredcites →https://doi.org/10.1016/0197-4580(93)90112-oopenalex-snapshot
New stereological methods for counting neurons
inferredcites →https://doi.org/10.1016/j.bcp.2006.07.012openalex-snapshot
Keeping up NF-κB appearances: Epigenetic control of immunity or inflammation-triggered epigenetics
inferredcites →https://doi.org/10.1016/j.cell.2007.08.019openalex-snapshot
The Histone H3 Lysine-27 Demethylase Jmjd3 Links Inflammation to Inhibition of Polycomb-Mediated Gene Silencing
inferredcites →https://doi.org/10.1016/j.cell.2009.01.038openalex-snapshot
A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death
inferredcites →https://doi.org/10.1016/j.it.2004.09.015openalex-snapshot
The chemokine system in diverse forms of macrophage activation and polarization
inferredcites →https://doi.org/10.1016/j.pneurobio.2005.06.004openalex-snapshot
Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
inferredcites →https://doi.org/10.1016/j.yexmp.2008.10.004openalex-snapshot
Role of nuclear transcription factor kappa B (NF-kappaB) for MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine)-induced apoptosis in nigral neurons of mice
inferredcites →https://doi.org/10.1016/s0006-8993(02)04085-4openalex-snapshot
Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice
inferredcites →https://doi.org/10.1016/s0165-5728(98)00217-3openalex-snapshot
Increased interleukin-6 expression by microglia from brain of aged mice
inferredcites →https://doi.org/10.1016/s0197-4580(02)00065-9openalex-snapshot
Staging of brain pathology related to sporadic Parkinson’s disease
inferredcites →https://doi.org/10.1016/s0896-6273(03)00568-3openalex-snapshot
Parkinson's Disease
inferredcites →https://doi.org/10.1038/70978openalex-snapshot
Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
inferredcites →https://doi.org/10.1038/77046openalex-snapshot
Gene-expression profile of the ageing brain in mice
inferredcites →https://doi.org/10.1038/nature05915openalex-snapshot
The complex language of chromatin regulation during transcription
inferredcites →https://doi.org/10.1038/nature06145openalex-snapshot
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
inferredcites →https://doi.org/10.1038/nature06270openalex-snapshot
SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron
inferredcites →https://doi.org/10.1038/nbt.1685openalex-snapshot
Epigenetic modifications and human disease
inferredcites →https://doi.org/10.1038/ni.1920openalex-snapshot
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
inferredcites →https://doi.org/10.1038/nn1997openalex-snapshot
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
inferredcites →https://doi.org/10.1038/nri1668openalex-snapshot
Regulation of immune responses by L-arginine metabolism
inferredcites →https://doi.org/10.1038/sj.cdd.4401989openalex-snapshot
Characterization of LPS and interferon-γ triggered activation-induced cell death in N9 and primary microglial cells: induction of the mitochondrial gateway by nitric oxide
inferredcites →https://doi.org/10.1038/sj.cdd.4402144openalex-snapshot
Glia: the fulcrum of brain diseases
inferredcites →https://doi.org/10.1073/pnas.0735876100openalex-snapshot
Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox
inferredcites →https://doi.org/10.1093/brain/awn230openalex-snapshot
Role of microglial IKKβ in kainic acid-induced hippocampal neuronal cell death
inferredcites →https://doi.org/10.1111/j.1471-4159.2010.06914.xopenalex-snapshot
Proteasome inhibition modeling nigral neuron degeneration in Parkinson’s disease
inferredcites →https://doi.org/10.1111/j.1749-6632.2002.tb04077.xopenalex-snapshot
Role of Nitric Oxide in Inflammation‐Mediated Neurodegeneration
inferredcites →https://doi.org/10.1161/atvbaha.111.229302openalex-snapshot
Arginase I Attenuates Inflammatory Cytokine Secretion Induced by Lipopolysaccharide in Vascular Smooth Muscle Cells
inferredcites →https://doi.org/10.1182/blood-2009-04-217620openalex-snapshot
Epigenetic regulation of the alternatively activated macrophage phenotype
inferredcites →https://doi.org/10.1189/jlb.0303114openalex-snapshot
Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification
inferredcites →https://doi.org/10.1515/revneuro.2002.13.3.221openalex-snapshot
Reciprocal Interactions Between Microglia and Neurons: From Survival to Neuropathology
inferredcites →https://doi.org/10.1523/jneurosci.21-21-08447.2001openalex-snapshot
Microglial Activation and Dopaminergic Cell Injury: AnIn VitroModel Relevant to Parkinson's Disease
inferredcites →https://doi.org/10.1523/jneurosci.2531-06.2006openalex-snapshot
Suppression of Microglial Inflammatory Activity by Myelin Phagocytosis: Role of p47-PHOX-Mediated Generation of Reactive Oxygen Species
inferredcites →https://doi.org/10.1523/jneurosci.3878-11.2011openalex-snapshot
Epigenetic Enhancement of BDNF Signaling Rescues Synaptic Plasticity in Aging
inferredcites →https://doi.org/10.2174/187152710791012053openalex-snapshot
Assessing Activation States in Microglia
inferredcites →https://doi.org/10.4049/jimmunol.0901088openalex-snapshot
Compound A, a Plant Origin Ligand of Glucocorticoid Receptors, Increases Regulatory T Cells and M2 Macrophages to Attenuate Experimental Autoimmune Neuritis with Reduced Side Effects
inferredcites →https://doi.org/10.4049/jimmunol.167.9.5004openalex-snapshot
Microglial Phagocytosis of Apoptotic Inflammatory T Cells Leads to Down-Regulation of Microglial Immune Activation

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Coptisine Improves Anxiety-Like Behaviors by Regulating the Warburg Effect in Microglia Via Pkm2
inferred← citeshttps://doi.org/10.1002/advs.202405537openalex-snapshot
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Pharmacokinetics, Pharmacodynamics, and Safety of a Single Escalating Dose and Repeated Doses of Rasagiline Transdermal Patch in Healthy Chinese Subjects
inferred← citeshttps://doi.org/10.1002/glia.23689openalex-snapshot
SIRPα deficiency accelerates the pathologic process in models of Parkinson disease
inferred← citeshttps://doi.org/10.1002/glia.23826openalex-snapshot
Nurr1 Cd11bcre conditional knockout mice display inflammatory injury to nigrostriatal dopaminergic neurons
inferred← citeshttps://doi.org/10.1002/glia.70035openalex-snapshot
Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice
inferred← citeshttps://doi.org/10.1002/ibra.12106openalex-snapshot
Aging‐related histone modification changes in brain function
inferred← citeshttps://doi.org/10.1002/jcp.26497openalex-snapshot
Histone methylation and acetylation in macrophages as a mechanism for regulation of inflammatory responses
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inferred← citeshttps://doi.org/10.1007/978-3-031-91072-2_13openalex-snapshot
Epigenetic Regulation Mediating Immunopathology in Parkinson’s Disease
inferred← citeshttps://doi.org/10.1007/978-3-319-08046-8_4openalex-snapshot
“Good” and “Bad” Microglia in Parkinson’s Disease: An Understanding of Homeostatic Mechanisms in Immunomodulation
inferred← citeshttps://doi.org/10.1007/978-3-319-40764-7_10openalex-snapshot
Age-Dependent Changes in the Activation and Regulation of Microglia
inferred← citeshttps://doi.org/10.1007/978-981-97-9877-3_39openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s00018-022-04536-3openalex-snapshot
The heterogeneity of microglial activation and its epigenetic and non-coding RNA regulations in the immunopathogenesis of neurodegenerative diseases
inferred← citeshttps://doi.org/10.1007/s00109-014-1182-xopenalex-snapshot
Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process
inferred← citeshttps://doi.org/10.1007/s00213-021-05912-wopenalex-snapshot
Human umbilical cord mesenchymal stem cells ameliorate depression by regulating Jmjd3 and microglia polarization in myocardial infarction mice
inferred← citeshttps://doi.org/10.1007/s00441-014-1924-7openalex-snapshot
Jumonji family histone demethylases in neural development
inferred← citeshttps://doi.org/10.1007/s00702-015-1438-9openalex-snapshot
G2019S LRRK2 and aging confer susceptibility to proteasome inhibitor-induced neurotoxicity in nigrostriatal dopaminergic system
inferred← citeshttps://doi.org/10.1007/s00702-016-1603-9openalex-snapshot
Therapies for Parkinson’s diseases: alternatives to current pharmacological interventions
inferred← citeshttps://doi.org/10.1007/s10072-020-04468-5openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10565-021-09669-yopenalex-snapshot
The H3K27 demethylase controls the lateral line embryogenesis of zebrafish
inferred← citeshttps://doi.org/10.1007/s10571-017-0504-2openalex-snapshot
Microglia: Housekeeper of the Central Nervous System
inferred← citeshttps://doi.org/10.1007/s10571-025-01564-yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10753-019-00977-4openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10753-022-01637-wopenalex-snapshot
Lactylation: a Passing Fad or the Future of Posttranslational Modification
inferred← citeshttps://doi.org/10.1007/s11064-020-03210-zopenalex-snapshot
Unlocking the Recovery Potential: JMJD3 Inhibition-Mediated SAPK/JNK Signaling Inactivation Supports Endogenous Oligodendrocyte-Lineage Commitment Post Mammalian Spinal Cord Injury
inferred← citeshttps://doi.org/10.1007/s11357-024-01223-yopenalex-snapshot
Rotating magnetic field improved cognitive and memory impairments in a sporadic ad model of mice by regulating microglial polarization
inferred← citeshttps://doi.org/10.1007/s12035-014-9070-5openalex-snapshot
Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1007/s12035-017-0532-4openalex-snapshot
Therapeutic Strategies Under Development Targeting Inflammatory Mechanisms in Amyotrophic Lateral Sclerosis
inferred← citeshttps://doi.org/10.1007/s12035-022-03120-xopenalex-snapshot
Fingolimod Alleviates Cognitive Deficit in Type 2 Diabetes by Promoting Microglial M2 Polarization via the pSTAT3-jmjd3 Axis
inferred← citeshttps://doi.org/10.1007/s12264-015-1539-3openalex-snapshot
Histone deacetylase 6 delays motor neuron degeneration by ameliorating the autophagic flux defect in a transgenic mouse model of amyotrophic lateral sclerosis
inferred← citeshttps://doi.org/10.1007/s13238-019-0653-9openalex-snapshot
JMJD3 in the regulation of human diseases
inferred← citeshttps://doi.org/10.1007/s13311-016-0463-1openalex-snapshot
Microglia and Monocyte-Derived Macrophages in Stroke
inferred← citeshttps://doi.org/10.1016/b978-0-12-802389-1.00016-2openalex-snapshot
Chromatin Signaling in Aging and Cellular Senescence
inferred← citeshttps://doi.org/10.1016/b978-0-12-816422-8.00007-6openalex-snapshot
Histone demethylase inhibitors and their potential in cancer treatment
inferred← citeshttps://doi.org/10.1016/b978-0-12-822368-0.00008-6openalex-snapshot
Microglia and macrophages in central nervous systems
inferred← citeshttps://doi.org/10.1016/b978-0-323-40139-5.00062-0openalex-snapshot
Neuroprotection Strategies for the Newborn
inferred← citeshttps://doi.org/10.1016/b978-0-443-19001-8.00018-0openalex-snapshot
Chromatin signaling in aging and cellular senescence
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2019.06.003openalex-snapshot
Blood-brain barrier and innate immunity in the pathogenesis of Alzheimer's disease
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MicroRNAs and their potential therapeutic applications in neural tissue engineering
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Metabolic regulation of immune cells in proinflammatory microenvironments and diseases during ageing
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Glial polarization in neurological diseases: Molecular mechanisms and therapeutic opportunities
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ACSL4 promotes microglia-mediated neuroinflammation by regulating lipid metabolism and VGLL4 expression
inferred← citeshttps://doi.org/10.1016/j.bbr.2025.115703openalex-snapshot
Low-grade chronic inflammatory stimulation alleviates α‑syn accumulation in Parkinson's disease by activating autophagy to promote neuronal survival in the Thy1-h[A30P]α-syn mouse model
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Activation of murine microglial N9 cells is attenuated through cannabinoid receptor CB2 signaling
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Small-molecule arone protects from neuroinflammation in LPS-activated microglia BV-2 cells by targeting histone-remodeling chaperone ASF1a
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KDM6B knockdown alleviates sleep deprivation-induced cerebrovascular lesions in APP/PS1 mice by inhibiting PARP16 expression
inferred← citeshttps://doi.org/10.1016/j.biocel.2015.07.006openalex-snapshot
JMJD3 as an epigenetic regulator in development and disease
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Emerging of lysine demethylases (KDMs): From pathophysiological insights to novel therapeutic opportunities
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Coptisine improves LPS-induced anxiety-like behaviors by regulating the Warburg effect in microglia via PKM2
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119893openalex-snapshot
Pleiotropic regulation of KDM6B in macrophage-associated physiological and pathological processes
inferred← citeshttps://doi.org/10.1016/j.cbi.2023.110387openalex-snapshot
Revisiting the intersection of microglial activation and neuroinflammation in Alzheimer's disease from the perspective of ferroptosis
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Neuro-immune dysfunction during brain aging: new insights in microglial cell regulation
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Epigenetic code and potential epigenetic-based therapies against chronic diseases in developmental origins
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Glutamine alleviates lead-induced neuroinflammation via αKG-JMJD3-H3K27me3 pathway: Population, animal, and in vitro evidence
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Retinal ganglion cell death in glaucoma: Exploring the role of neuroinflammation
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EGb761 improves cognitive function and regulates inflammatory responses in the APP/PS1 mouse
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Microglia in the TBI brain: The good, the bad, and the dysregulated
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TREM2 overexpression rescues cognitive deficits in APP/PS1 transgenic mice by reducing neuroinflammation via the JAK/STAT/SOCS signaling pathway
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The interplay between neuroinflammatory pathways and Parkinson's disease
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Microglial hyperactivation and NLRP3 methylation mediated by SETD3 after anesthesia/surgery: Unraveling new mechanisms of perioperative neurocognitive disorders
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Analysis of multidimensional molecular mechanisms in Parkinson's disease and precise therapeutic strategies
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One-carbon epigenetics and redox biology of neurodegeneration
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Nutritional neurology: Unraveling cellular mechanisms of natural supplements in brain health
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CSB6B prevents β-amyloid-associated neuroinflammation and cognitive impairments via inhibiting NF-κB and NLRP3 in microglia cells
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Pseudoginsenoside-F11 promotes functional recovery after transient cerebral ischemia by regulating the microglia/macrophage polarization in rats
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Therapeutic Epigenetic Reprogramming of Trained Immunity in Myeloid Cells
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Iron scavenging and myeloid cell polarization
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EZH2 is involved in vulnerability to neuroinflammation and depression-like behaviors induced by chronic stress in different aged mice
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Histone H3K27 Demethylase JMJD3 in Cooperation with NF-κB Regulates Keratinocyte Wound Healing
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The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival
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Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury
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Neuroinflammation: An overview of neurodegenerative and metabolic diseases and of biotechnological studies
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Long non-coding RNA: An underlying bridge linking neuroinflammation and central nervous system diseases
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Epigenetic regulation in the neurogenic niche of the adult dentate gyrus
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The role of ACE2 in RAS axis on microglia activation in Parkinson’s disease
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Liver X receptor α contribution to neuroinflammation and glial cells activation induced by MPTP: Implications for Parkinson’s disease
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Epigenetic mechanisms linking environmental exposure to Parkinson’s disease: A comprehensive review
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Dietary nutrition for neurological disease therapy: Current status and future directions
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Alternatively activated microglia and macrophages in the central nervous system
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Neurosteroids as regulators of neuroinflammation
inferred← citeshttps://doi.org/10.1021/acs.jcim.8b00539openalex-snapshot
In Silico Identification of JMJD3 Demethylase Inhibitors
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.8b00589openalex-snapshot
Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition
inferred← citeshttps://doi.org/10.1038/aps.2016.162openalex-snapshot
Regulation of microglial activation in stroke
inferred← citeshttps://doi.org/10.1038/icb.2014.114openalex-snapshot
Epigenetic modifications of the immune system in health and disease
inferred← citeshttps://doi.org/10.1038/mp.2017.167openalex-snapshot
DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway
inferred← citeshttps://doi.org/10.1038/s41380-021-01186-yopenalex-snapshot
Neuroadaptations and TGF-β signaling: emerging role in models of neuropsychiatric disorders
inferred← citeshttps://doi.org/10.1038/s41392-022-01145-1openalex-snapshot
JMJD family proteins in cancer and inflammation
inferred← citeshttps://doi.org/10.1038/s41419-018-0437-9openalex-snapshot
Kir6.1/K-ATP channel modulates microglia phenotypes: implication in Parkinson’s disease
inferred← citeshttps://doi.org/10.1038/s41419-018-0468-2openalex-snapshot
Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization
inferred← citeshttps://doi.org/10.1038/s41419-018-0821-5openalex-snapshot
A lincRNA-p21/miR-181 family feedback loop regulates microglial activation during systemic LPS- and MPTP- induced neuroinflammation
inferred← citeshttps://doi.org/10.1038/s41419-021-03412-5openalex-snapshot
Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration
inferred← citeshttps://doi.org/10.1038/s41531-022-00352-5openalex-snapshot
Melatonin ameliorates Parkinson’s disease via regulating microglia polarization in a RORα‐dependent pathway
inferred← citeshttps://doi.org/10.1038/s41577-024-01104-7openalex-snapshot
Neuroinflammation in Alzheimer disease
inferred← citeshttps://doi.org/10.1042/an20130050openalex-snapshot
Cell-Type-Specific Jumonji Histone Demethylase Gene Expression in the Healthy Rat CNS: Detection by a Novel Flow Cytometry Method
inferred← citeshttps://doi.org/10.1080/14728222.2018.1515917openalex-snapshot
Recent progress in therapeutic strategies for microglia-mediated neuroinflammation in neuropathologies
inferred← citeshttps://doi.org/10.1080/17460441.2018.1465925openalex-snapshot
Identification of glia phenotype modulators based on select glial function regulatory signaling pathways
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Review article: the role of epigenetics as an underlying regulator of the immune responses in Parkinson’s disease
inferred← citeshttps://doi.org/10.1089/ars.2024.0605openalex-snapshot
H 2 S Donor SPRC Ameliorates Cardiac Aging by Suppression of JMJD3, a Histone Demethylase
inferred← citeshttps://doi.org/10.1089/scd.2018.0258openalex-snapshot
Inhibition of Ezh2 In Vitro and the Decline of Ezh2 in Developing Midbrain Promote Dopaminergic Neurons Differentiation Through Modifying H3K27me3
inferred← citeshttps://doi.org/10.1089/scd.2019.0216openalex-snapshot
RNA-Seq Reveals Underlying Transcriptomic Mechanisms of Bone Marrow-Derived Mesenchymal Stem Cells in the Regulation of Microglia-Mediated Neuroinflammation After Subarachnoid Hemorrhage
inferred← citeshttps://doi.org/10.1093/hmg/ddad115openalex-snapshot
JMJD3 and SNAI2 synergistically protect against Parkinson’s disease by mediating the YAP/HIF1α signaling pathway in a mouse model
inferred← citeshttps://doi.org/10.1093/hmg/ddz110openalex-snapshot
RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways
inferred← citeshttps://doi.org/10.1097/md.0000000000032991openalex-snapshot
Postoperative delirium, neuroinflammation, and influencing factors of postoperative delirium: A review
inferred← citeshttps://doi.org/10.1111/adb.12816openalex-snapshot
Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways
inferred← citeshttps://doi.org/10.1111/bpa.13028openalex-snapshot
Chronic sleep deprivation altered the expression of circadian clock genes and aggravated Alzheimer's disease neuropathology
inferred← citeshttps://doi.org/10.1111/bph.13139openalex-snapshot
Microglial M1/M2 polarization and metabolic states
inferred← citeshttps://doi.org/10.1111/cen3.12492openalex-snapshot
Neuroimmunological phenomena involved in chronic traumatic brain injury
inferred← citeshttps://doi.org/10.1111/jnc.15327openalex-snapshot
Microglial phagocytosis of neurons in neurodegeneration, and its regulation
inferred← citeshttps://doi.org/10.1111/neup.12180openalex-snapshot
Short‐, middle‐ and long‐term safety of superparamagnetic iron oxide‐labeled allogeneic bone marrow stromal cell transplantation in rat model of lacunar infarction
inferred← citeshttps://doi.org/10.1113/jp271502openalex-snapshot
Mechanisms of microglial activation in models of inflammation and hypoxia: Implications for chronic intermittent hypoxia
inferred← citeshttps://doi.org/10.1146/annurev-med-050715-104343openalex-snapshot
Innate Immunity and Neurodegeneration
inferred← citeshttps://doi.org/10.1155/2016/4854378openalex-snapshot
Cannabinoid CB2 Receptor Mediates Nicotine-Induced Anti-Inflammation in N9 Microglial Cells Exposed toβAmyloid via Protein Kinase C
inferred← citeshttps://doi.org/10.1155/2016/6591703openalex-snapshot
Epigenetic Control of Macrophage Polarisation and Soluble Mediator Gene Expression during Inflammation
inferred← citeshttps://doi.org/10.1155/2021/9912686openalex-snapshot
Epigenetic Modulation of Microglia Function and Phenotypes in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1155/2022/9404977openalex-snapshot
Age of Rats Affects the Degree of Retinal Neuroinflammatory Response Induced by High Acute Intraocular Pressure
inferred← citeshttps://doi.org/10.11606/d.42.2023.tde-13122023-155346openalex-snapshot
Caracterização epigenética nos núcleos respiratórios no modelo animal 6-OHDA da doença de Parkinson.
inferred← citeshttps://doi.org/10.1177/0271678x20951995openalex-snapshot
Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity
inferred← citeshttps://doi.org/10.1177/13872877241288709openalex-snapshot
The impact of sex on memory during aging and Alzheimer's disease progression: Epigenetic mechanisms
inferred← citeshttps://doi.org/10.1186/preaccept-4817442551293959openalex-snapshot
Suppression of histone deacetylation promotes the differentiation of human pluripotent stem cells towards neural progenitor cells
inferred← citeshttps://doi.org/10.1186/s12964-024-02006-wopenalex-snapshot
Histone demethylases in autophagy and inflammation
inferred← citeshttps://doi.org/10.1186/s12967-025-07388-0openalex-snapshot
Single-cell transcriptome analysis reveals mechanisms by which hippocampal deep brain stimulation promotes neurorepair and microglial subpopulation remodeling in ischemic stroke
inferred← citeshttps://doi.org/10.1186/s12974-015-0302-zopenalex-snapshot
Electroacupuncture remediates glial dysfunction and ameliorates neurodegeneration in the astrocytic α-synuclein mutant mouse model
inferred← citeshttps://doi.org/10.1186/s12974-017-0866-xopenalex-snapshot
YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by β-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2
inferred← citeshttps://doi.org/10.1186/s12974-019-1641-yopenalex-snapshot
DHEA Attenuates Microglial Activation via Induction of JMJD3 in Experimental Subarachnoid Haemorrhage
inferred← citeshttps://doi.org/10.1186/s12974-021-02209-9openalex-snapshot
Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model
inferred← citeshttps://doi.org/10.1186/s12974-023-02723-yopenalex-snapshot
The reciprocal interactions between microglia and T cells in Parkinson’s disease: a double-edged sword
inferred← citeshttps://doi.org/10.1186/s12974-024-03024-8openalex-snapshot
Modeling the neuroimmune system in Alzheimer’s and Parkinson’s diseases
inferred← citeshttps://doi.org/10.1186/s12974-026-03863-7openalex-snapshot
Pulmonary microbiota–associated formononetin modulates microglial activation in asthma-related anxiety
inferred← citeshttps://doi.org/10.1186/s12987-025-00690-5openalex-snapshot
Imatinib prevents blood-spinal cord barrier disruption by inhibiting PDGFR-mediated JMJD3 expression and activation after spinal cord injury
inferred← citeshttps://doi.org/10.1186/s13148-016-0202-9openalex-snapshot
TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus
inferred← citeshttps://doi.org/10.1186/s40035-015-0042-0openalex-snapshot
Neuroinflammation in Parkinson’s disease and its potential as therapeutic target
inferred← citeshttps://doi.org/10.1186/s40035-020-00221-2openalex-snapshot
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
inferred← citeshttps://doi.org/10.1186/s40364-024-00621-wopenalex-snapshot
Lysine methylation modifications in tumor immunomodulation and immunotherapy: regulatory mechanisms and perspectives
inferred← citeshttps://doi.org/10.1186/s40478-024-01912-xopenalex-snapshot
JMJD3 deficiency disturbs dopamine biosynthesis in midbrain and aggravates chronic inflammatory pain
inferred← citeshttps://doi.org/10.1186/s41232-024-00320-xopenalex-snapshot
Rapid and high-purity differentiation of human medium spiny neurons reveals LMNB1 hypofunction and subtype necessity in modeling Huntington’s disease
inferred← citeshttps://doi.org/10.1186/s41544-019-0031-zopenalex-snapshot
Viral infection and neurological disorders—potential role of extracellular nucleotides in neuroinflammation
inferred← citeshttps://doi.org/10.1186/s43556-026-00434-3openalex-snapshot
The JMJD family histone demethylases: structure, mechanism of action, diseases and therapeutic targets
inferred← citeshttps://doi.org/10.1210/endocr/bqac047openalex-snapshot
Jumonji Domain–containing Protein-3 (JMJD3/Kdm6b) Is Critical for Normal Ovarian Function and Female Fertility
inferred← citeshttps://doi.org/10.1371/journal.pone.0341313openalex-snapshot
JMJD3 regulates the M2-like macrophage polarization and promotes the growth of breast cancer cells via STAT6/IRF4 axis
inferred← citeshttps://doi.org/10.14336/ad.2020.0701openalex-snapshot
Microglial Polarization: Novel Therapeutic Strategy against Ischemic Stroke
inferred← citeshttps://doi.org/10.1515/hsz-2014-0180openalex-snapshot
The epigenetic tracks of aging
inferred← citeshttps://doi.org/10.1523/jneurosci.1001-15.2015openalex-snapshot
Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity
inferred← citeshttps://doi.org/10.15252/emmm.201404610openalex-snapshot
Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease
inferred← citeshttps://doi.org/10.15761/jsin.1000155openalex-snapshot
The role of cell based therapy in the treatment of Parkinson’s disease
inferred← citeshttps://doi.org/10.17691/stm2021.13.6.10openalex-snapshot
Current Methods for the Isolation and Cultivation of Microglia (Review)
inferred← citeshttps://doi.org/10.18632/aging.100740openalex-snapshot
Coronary artery calcifications predict long term cardiovascular events in non diabetic Caucasian hemodialysis patients
inferred← citeshttps://doi.org/10.18632/oncotarget.17027openalex-snapshot
Promising landscape for regulating macrophage polarization: epigenetic viewpoint
inferred← citeshttps://doi.org/10.20935/acadbiol7909openalex-snapshot
Molecular pathways and biomarkers associated with age-related cognitive decline
inferred← citeshttps://doi.org/10.2174/1381612825666190722114248openalex-snapshot
Heterogeneity of Microglia Phenotypes: Developmental, Functional and Some Therapeutic Considerations
inferred← citeshttps://doi.org/10.2174/1568026619666190619143706openalex-snapshot
Epigenetic Modification in Macrophages: A Promising Target for Tumor and Inflammation-associated Disease Therapy
inferred← citeshttps://doi.org/10.2174/1568026619666191202155738openalex-snapshot
Neuroprotection with Natural Antioxidants and Nutraceuticals in the Context of Brain Cell Degeneration: The Epigenetic Connection
inferred← citeshttps://doi.org/10.2174/9789815238754124010010openalex-snapshot
Epigenetic Regulation of Microglia: Plausible Mechanism and Interventional Approaches in Neurodegeneration
inferred← citeshttps://doi.org/10.2463/mrms.mp.2015-0090openalex-snapshot
11.7 T MR Imaging Revealed Dilatation of Virchow–Robin Spaces within Hippocampus in Maternally Lipopolysaccharide-exposed Rats
inferred← citeshttps://doi.org/10.31274/td-20240329-388openalex-snapshot
Histone Acetylation Contributes to Mitochondrial Dysfunction and Neuroinflammation in Parkinson's disease
inferred← citeshttps://doi.org/10.3233/jad-200099openalex-snapshot
M2-Like Microglia Polarization Attenuates Neuropathic Pain Associated with Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3384/diss.diva-160949openalex-snapshot
The Propagation of Neurodegenerative Diseases by Inflammation and Exosomes
inferred← citeshttps://doi.org/10.33882/clinicaldent.15.39854openalex-snapshot
Tissue Engineering in Periodontal Regeneration – A Review
inferred← citeshttps://doi.org/10.3389/fendo.2019.00719openalex-snapshot
Overexpression of miR-146a Might Regulate Polarization Transitions of BV-2 Cells Induced by High Glucose and Glucose Fluctuations
inferred← citeshttps://doi.org/10.3389/fgene.2023.1135404openalex-snapshot
Epigenetics and immune cells in medulloblastoma
inferred← citeshttps://doi.org/10.3389/fimmu.2022.1094132openalex-snapshot
Protective effects of blocking PD-1 pathway on retinal ganglion cells in a mouse model of chronic ocular hypertension
inferred← citeshttps://doi.org/10.3389/fnagi.2017.00176openalex-snapshot
Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson’s Disease
inferred← citeshttps://doi.org/10.3389/fnagi.2017.00194openalex-snapshot
Aging Microglia—Phenotypes, Functions and Implications for Age-Related Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.3389/fnagi.2017.00282openalex-snapshot
Acute Hypoxia Induced an Imbalanced M1/M2 Activation of Microglia through NF-κB Signaling in Alzheimer’s Disease Mice and Wild-Type Littermates
inferred← citeshttps://doi.org/10.3389/fnagi.2021.772717openalex-snapshot
Microglia Polarization in Alzheimer’s Disease: Mechanisms and a Potential Therapeutic Target
inferred← citeshttps://doi.org/10.3389/fnagi.2022.815347openalex-snapshot
Microglia Polarization From M1 to M2 in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.3389/fncel.2016.00098openalex-snapshot
Inflammogenesis of Secondary Spinal Cord Injury
inferred← citeshttps://doi.org/10.3389/fncel.2018.00243openalex-snapshot
Epigenetics Control Microglia Plasticity
inferred← citeshttps://doi.org/10.3389/fncel.2019.00453openalex-snapshot
The Role of Neuronal Factors in the Epigenetic Reprogramming of Microglia in the Normal and Diseased Central Nervous System
inferred← citeshttps://doi.org/10.3389/fncel.2019.00542openalex-snapshot
Editorial: Linking Neuroinflammation and Glial Phenotypic Changes in Neurological Diseases
inferred← citeshttps://doi.org/10.3389/fncel.2020.00209openalex-snapshot
Glia Crosstalk in Neuroinflammatory Diseases
inferred← citeshttps://doi.org/10.3389/fncel.2025.1669272openalex-snapshot
Glioinflammation: disease-associated microglia and astrocytes in psychiatric disorders, neurodegeneration, and senescence
inferred← citeshttps://doi.org/10.3389/fneur.2018.00860openalex-snapshot
Outside in: Unraveling the Role of Neuroinflammation in the Progression of Parkinson's Disease
inferred← citeshttps://doi.org/10.3389/fneur.2022.921705openalex-snapshot
The dual function of microglial polarization and its treatment targets in ischemic stroke
inferred← citeshttps://doi.org/10.3389/fnins.2016.00061openalex-snapshot
Interleukin-4 Ameliorates the Functional Recovery of Intracerebral Hemorrhage Through the Alternative Activation of Microglia/Macrophage
inferred← citeshttps://doi.org/10.3389/fnins.2018.00314openalex-snapshot
Impacts of Acute Hypoxia on Alzheimer's Disease-Like Pathologies in APPswe/PS1dE9 Mice and Their Wild Type Littermates
inferred← citeshttps://doi.org/10.3389/fnins.2019.00277openalex-snapshot
Entanglement of Genetics and Epigenetics in Parkinson’s Disease
inferred← citeshttps://doi.org/10.3389/fnmol.2016.00089openalex-snapshot
Protective Microglia and Their Regulation in Parkinson’s Disease
inferred← citeshttps://doi.org/10.3389/fnmol.2017.00359openalex-snapshot
Direct Reprogramming Rather than iPSC-Based Reprogramming Maintains Aging Hallmarks in Human Motor Neurons
inferred← citeshttps://doi.org/10.3389/fnmol.2021.697416openalex-snapshot
Epigenetic Regulations of Microglia/Macrophage Polarization in Ischemic Stroke
inferred← citeshttps://doi.org/10.3389/fnut.2024.1425839openalex-snapshot
Neurodegenerative diseases and catechins: (−)-epigallocatechin-3-gallate is a modulator of chronic neuroinflammation and oxidative stress
inferred← citeshttps://doi.org/10.3389/fragi.2023.1231706openalex-snapshot
The dual face of microglia (M1/M2) as a potential target in the protective effect of nutraceuticals against neurodegenerative diseases
inferred← citeshttps://doi.org/10.3390/antiox12061281openalex-snapshot
Anti-Neuroinflammatory Effects of the Human Milk Oligosaccharide, 2′-Fucosyllactose, Exerted via Modulation of M2 Microglial Activation in a Mouse Model of Ischemia–Reperfusion Injury
inferred← citeshttps://doi.org/10.3390/antiox13020178openalex-snapshot
Management of the Brain: Essential Oils as Promising Neuroinflammation Modulator in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.3390/biology13121008openalex-snapshot
Epigenetic Modifiers: Exploring the Roles of Histone Methyltransferases and Demethylases in Cancer and Neurodegeneration
inferred← citeshttps://doi.org/10.3390/biology14080955openalex-snapshot
Exercise Ameliorates Dopaminergic Neurodegeneration in Parkinson’s Disease Mice by Suppressing Microglia-Regulated Neuroinflammation Through Irisin/AMPK/Sirt1 Pathway
inferred← citeshttps://doi.org/10.3390/biom11020306openalex-snapshot
Epigenetics and Communication Mechanisms in Microglia Activation with a View on Technological Approaches
inferred← citeshttps://doi.org/10.3390/biomedicines12081737openalex-snapshot
Aged-Related Changes in Microglia and Neurodegenerative Diseases: Exploring the Connection
inferred← citeshttps://doi.org/10.3390/cells13010079openalex-snapshot
Epigenetic Regulation of Neuroinflammation in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3390/cells9071687openalex-snapshot
Inflammation in Parkinson’s Disease: Mechanisms and Therapeutic Implications
inferred← citeshttps://doi.org/10.3390/cells9071717openalex-snapshot
Microglia: Agents of the CNS Pro-Inflammatory Response
inferred← citeshttps://doi.org/10.3390/ijms19103199openalex-snapshot
Pharmacoepigenomic Interventions as Novel Potential Treatments for Alzheimer’s and Parkinson’s Diseases
inferred← citeshttps://doi.org/10.3390/ijms21239074openalex-snapshot
Synthesis, Molecular Modeling and Biological Evaluation of Metabolically Stable Analogues of the Endogenous Fatty Acid Amide Palmitoylethanolamide
inferred← citeshttps://doi.org/10.3390/ijms22094956openalex-snapshot
Epigenetic Regulation of Neuroinflammation in Parkinson’s Disease
inferred← citeshttps://doi.org/10.3390/ijms232315218openalex-snapshot
The Role of Epigenetics in Neuroinflammatory-Driven Diseases
inferred← citeshttps://doi.org/10.3390/ijms242417339openalex-snapshot
Insights into the Role of Histone Methylation in Brain Aging and Potential Therapeutic Interventions
inferred← citeshttps://doi.org/10.3390/jcm8101719openalex-snapshot
Reformulating Pro-Oxidant Microglia in Neurodegeneration
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