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Overcoming Insulin Insufficiency by Forced Follistatin Expression in β -cells of db/db Mice
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1 of the 54 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1016/j.cell.2013.04.008 (notice 2017-01-01).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1096-9136(199804)15:4<290::aid-dia570>3.0.co;2-mopenalex-snapshot
Beta-cell deterioration determines the onset and rate of progression of secondary dietary failure in Type 2 diabetes mellitus: the 10-year follow-up of the Belfast Diet Study
inferredcites →https://doi.org/10.1002/dme.1996.13.s6.103openalex-snapshot
Insulin Resistance and Growth Retardation in Mice Lacking Insulin Receptor Substrate‐1 and Identification of Insulin Receptor Substrate‐2
inferredcites →https://doi.org/10.1002/dmrr.2350openalex-snapshot
Second line therapy: type 2 diabetic subjects failing on metformin GLP‐1/DPP‐IV inhibitors versus sulphonylurea/insulin: For GLP‐1/DPP‐IV inhibitors
inferredcites →https://doi.org/10.1002/jcp.20477openalex-snapshot
Myostatin auto‐regulates its expression by feedback loop through Smad7 dependent mechanism
inferredcites →https://doi.org/10.1002/mus.21244openalex-snapshot
Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease
inferredcites →https://doi.org/10.1006/dbio.1998.8893openalex-snapshot
Xenopus Smad7 Inhibits both the Activin and BMP Pathways and Acts as a Neural Inducer
inferredcites →https://doi.org/10.1007/bf03343713openalex-snapshot
Activin A stimulates insulin secretion in cultured human pancreatic islets
inferredcites →https://doi.org/10.1007/s12020-008-9039-0openalex-snapshot
ID2 promotes the expansion and survival of growth-arrested pancreatic beta cells
inferredcites →https://doi.org/10.1016/b978-0-12-385961-7.00011-1openalex-snapshot
Activin in Glucose Metabolism
inferredcites →https://doi.org/10.1016/j.cell.2005.05.027openalex-snapshot
Loss of ARNT/HIF1β Mediates Altered Gene Expression and Pancreatic-Islet Dysfunction in Human Type 2 Diabetes
inferredcites →https://doi.org/10.1016/j.cell.2013.04.008openalex-snapshot
RETRACTED: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation
inferredcites →https://doi.org/10.1016/j.clinthera.2011.04.008openalex-snapshot
Evaluating Treatment Algorithms for the Management of Patients With Type 2 Diabetes Mellitus: A Perspective on the Definition of Treatment Success
inferredcites →https://doi.org/10.1016/j.cmet.2011.04.013openalex-snapshot
Protection from Obesity and Diabetes by Blockade of TGF-β/Smad3 Signaling
inferredcites →https://doi.org/10.1016/j.mce.2004.02.010openalex-snapshot
Autocrine/paracrine regulation of pituitary function by activin, inhibin and follistatin
inferredcites →https://doi.org/10.1016/j.mce.2012.02.015openalex-snapshot
Roles of activin family in pancreatic development and homeostasis
inferredcites →https://doi.org/10.1016/j.tem.2009.03.002openalex-snapshot
Akt and PTEN: β-cell mass and pancreas plasticity
inferredcites →https://doi.org/10.1016/j.yexcr.2011.01.010openalex-snapshot
GLP-1 for type 2 diabetes
inferredcites →https://doi.org/10.1016/s0092-8674(00)81294-5openalex-snapshot
Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice
inferredcites →https://doi.org/10.1016/s0140-6736(12)61031-9openalex-snapshot
Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy
inferredcites →https://doi.org/10.1016/s0962-8924(97)01036-2openalex-snapshot
TGF-β signalling through the Smad pathway
inferredcites →https://doi.org/10.1038/46794openalex-snapshot
Silencing of TGF-β signalling by the pseudoreceptor BAMBI
inferredcites →https://doi.org/10.1038/cr.2008.327openalex-snapshot
Phospho-control of TGF-β superfamily signaling
inferredcites →https://doi.org/10.1038/gt.2009.157openalex-snapshot
High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency
inferredcites →https://doi.org/10.1038/nature13633openalex-snapshot
Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers
inferredcites →https://doi.org/10.1038/oby.2011.97openalex-snapshot
Follistatin and Follistatin Like‐3 Differentially Regulate Adiposity and Glucose Homeostasis
inferredcites →https://doi.org/10.1038/sj.gt.3302530openalex-snapshot
Efficient gene delivery to human and rodent islets with double-stranded (ds) AAV-based vectors
inferredcites →https://doi.org/10.1073/pnas.0505996102openalex-snapshot
Regulation of muscle growth by multiple ligands signaling through activin type II receptors
inferredcites →https://doi.org/10.1073/pnas.0607966104openalex-snapshot
FSTL3 deletion reveals roles for TGF-β family ligands in glucose and fat homeostasis in adults
inferredcites →https://doi.org/10.1074/jbc.m111.293381openalex-snapshot
Inhibin α-Subunit N Terminus Interacts with Activin Type IB Receptor to Disrupt Activin Signaling
inferredcites →https://doi.org/10.1074/jbc.m801045200openalex-snapshot
Suppression of Inhibin A Biological Activity by Alterations in the Binding Site for Betaglycan
inferredcites →https://doi.org/10.1074/jbc.m805379200openalex-snapshot
Transforming Growth Factor-β/Smad3 Signaling Regulates Insulin Gene Transcription and Pancreatic Islet β-Cell Function
inferredcites →https://doi.org/10.1089/hum.2007.159openalex-snapshot
Myostatin Propeptide Gene Delivery by Adeno-Associated Virus Serotype 8 Vectors Enhances Muscle Growth and Ameliorates Dystrophic Phenotypes in mdx Mice
inferredcites →https://doi.org/10.1093/jb/mvt046openalex-snapshot
New insights into extracellular and post-translational regulation of TGF- family signalling pathways
inferredcites →https://doi.org/10.1093/qjmed/hcg040openalex-snapshot
Deteriorating beta‐cell function in type 2 diabetes: a long‐term model
inferredcites →https://doi.org/10.1097/mjt.0b013e3181afbf51openalex-snapshot
Advances in the Treatment of Type 2 Diabetes Mellitus
inferredcites →https://doi.org/10.1111/j.1463-1326.2007.00783.xopenalex-snapshot
Regulation of β‐cell mass and function by the Akt/protein kinase B signalling pathway
inferredcites →https://doi.org/10.1126/science.2106159openalex-snapshot
Activin-Binding Protein from Rat Ovary Is Follistatin
inferredcites →https://doi.org/10.1126/science.296.5573.1655openalex-snapshot
The Phosphoinositide 3-Kinase Pathway
inferredcites →https://doi.org/10.1126/scitranslmed.3000112openalex-snapshot
Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates
inferredcites →https://doi.org/10.1128/jvi.76.24.13015-13027.2002openalex-snapshot
A Novel Gene Expression Control System and Its Use in Stable, High-Titer 293 Cell-Based Adeno-Associated Virus Packaging Cell Lines
inferredcites →https://doi.org/10.1139/cjpp-2014-0114openalex-snapshot
Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2
inferredcites →https://doi.org/10.1152/ajpendo.00193.2009openalex-snapshot
Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin
inferredcites →https://doi.org/10.1155/2012/381713openalex-snapshot
Choosing between GLP-1 Receptor Agonists and DPP-4 Inhibitors: A Pharmacological Perspective
inferredcites →https://doi.org/10.1159/000350831openalex-snapshot
Fit Yourself and Take Your Lungs to Heart
inferredcites →https://doi.org/10.1210/en.2002-0124openalex-snapshot
Expression of Bambi Is Widespread in Juvenile and Adult Rat Tissues and Is Regulated in Male Germ Cells
inferredcites →https://doi.org/10.1210/en.2006-0089openalex-snapshot
Biological Activity of Follistatin Isoforms and Follistatin-Like-3 Is Dependent on Differential Cell Surface Binding and Specificity for Activin, Myostatin, and Bone Morphogenetic Proteins
inferredcites →https://doi.org/10.1371/journal.pbio.0040039openalex-snapshot
Conditional Expression of Smad7 in Pancreatic β Cells Disrupts TGF-β Signaling and Induces Reversible Diabetes Mellitus
inferredcites →https://doi.org/10.1517/17460441.2013.741580openalex-snapshot
Discovery and development of exenatide: the first antidiabetic agent to leverage the multiple benefits of the incretin hormone, GLP-1
inferredcites →https://doi.org/10.2337/db12-0018openalex-snapshot
Human β-Cell Proliferation and Intracellular Signaling
inferredcites →https://doi.org/10.2337/db12-1428openalex-snapshot
TGFβ Receptor Signaling Is Essential for Inflammation-Induced but Not β-Cell Workload–Induced β-Cell Proliferation
inferredcites →https://doi.org/10.2337/db13-0432openalex-snapshot
A Smad Signaling Network Regulates Islet Cell Proliferation
inferredcites →https://doi.org/10.2337/diabetes.55.04.06.db05-0927openalex-snapshot
Widespread and Stable Pancreatic Gene Transfer by Adeno-Associated Virus Vectors via Different Routes
inferredcites →https://doi.org/10.4161/isl.3.6.18013openalex-snapshot
Differential synthesis and action of TGFβ superfamily ligands in mouse and rat islets
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4789208openalex-extracted
Unlocking Regenerative Potential: Beta-Cell Neogenesis and Novel Myokines Involved in Adaptation to Insulin Resistance in Mice
inferred← citeshttps://doi.org/10.1002/jcp.30033openalex-snapshot
Myokines mediate the cross talk between skeletal muscle and other organs
inferred← citeshttps://doi.org/10.1002/jcsm.13692openalex-snapshot
The Effect of Exercise on Spexin and Follistatin in Elderly Individuals
inferred← citeshttps://doi.org/10.1007/s12026-024-09470-zopenalex-snapshot
Hormone and reproductive factors and risk of systemic lupus erythematosus: a Mendelian randomized study
inferred← citeshttps://doi.org/10.1016/j.apsb.2026.01.018openalex-snapshot
Liver–pancreas communication in disease and drug development
inferred← citeshttps://doi.org/10.1016/j.bbadis.2024.167055openalex-snapshot
Therapeutic potential of AAV-FL-Klotho in obesity: Impact on weight loss and lipid metabolism in mice
inferred← citeshttps://doi.org/10.1016/j.isci.2023.106451openalex-snapshot
Steroidogenic factor 1 protects mice from obesity-induced glucose intolerance via improving glucose-stimulated insulin secretion by beta cells
inferred← citeshttps://doi.org/10.1016/j.kint.2019.05.032openalex-snapshot
The caveolin-1 regulated protein follistatin protects against diabetic kidney disease
inferred← citeshttps://doi.org/10.1016/j.molmet.2020.101138openalex-snapshot
Hepatokines and metabolism: Deciphering communication from the liver
inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2023.106785openalex-snapshot
Follistatin and follistatin-like 3 in metabolic disorders
inferred← citeshttps://doi.org/10.1016/j.tem.2020.11.006openalex-snapshot
A Decade Later: Revisiting the TGFβ Family’s Role in Diabetes
inferred← citeshttps://doi.org/10.1038/emm.2017.135openalex-snapshot
Follistatin N terminus differentially regulates muscle size and fat in vivo
inferred← citeshttps://doi.org/10.1038/s41467-021-26536-wopenalex-snapshot
Elevated circulating follistatin associates with an increased risk of type 2 diabetes
inferred← citeshttps://doi.org/10.1038/s41467-026-72077-5openalex-snapshot
TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network
inferred← citeshttps://doi.org/10.1038/s41556-022-00919-7openalex-snapshot
Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth
inferred← citeshttps://doi.org/10.1038/s41598-019-44076-8openalex-snapshot
ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes
inferred← citeshttps://doi.org/10.1038/s41598-021-88105-xopenalex-snapshot
Resistance exercise training improves glucose homeostasis by enhancing insulin secretion in C57BL/6 mice
inferred← citeshttps://doi.org/10.1096/fj.201700064ropenalex-snapshot
Adeno‐associated virus 9–mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model
inferred← citeshttps://doi.org/10.1096/fj.201802059rrropenalex-snapshot
Intravascular Follistatin gene delivery improves glycemic control in a mouse model of type 2 diabetes
inferred← citeshttps://doi.org/10.1126/scitranslmed.abb1038openalex-snapshot
Paired box 6 programs essential exocytotic genes in the regulation of glucose-stimulated insulin secretion and glucose homeostasis
inferred← citeshttps://doi.org/10.1139/apnm-2018-0818openalex-snapshot
Effect of exercise intensity on circulating hepatokine concentrations in healthy men
inferred← citeshttps://doi.org/10.1139/cjpp-2014-0114openalex-snapshot
Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2
inferred← citeshttps://doi.org/10.1152/ajpendo.00353.2017openalex-snapshot
Do skeletal muscle-secreted factors influence the function of pancreatic β-cells?
inferred← citeshttps://doi.org/10.1152/ajpendo.00433.2018openalex-snapshot
Role of exercise-induced hepatokines in metabolic disorders
inferred← citeshttps://doi.org/10.1172/jci.insight.131610openalex-snapshot
Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors
inferred← citeshttps://doi.org/10.1210/clinem/dgaa090openalex-snapshot
Circulating Follistatin and Activin A and Their Regulation by Insulin in Obesity and Type 2 Diabetes
inferred← citeshttps://doi.org/10.1210/jc.2015-3668openalex-snapshot
Circulating Follistatin Is Liver-Derived and Regulated by the Glucagon-to-Insulin Ratio
inferred← citeshttps://doi.org/10.1210/jc.2016-1681openalex-snapshot
Exercise-Induced Secretion of FGF21 and Follistatin Are Blocked by Pancreatic Clamp and Impaired in Type 2 Diabetes
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3734627/v1openalex-snapshot
Cross-talk between hepatokines as Liver indused-exercise factors and organokines
inferred← citeshttps://doi.org/10.3389/fendo.2021.653179openalex-snapshot
Novel Roles of Follistatin/Myostatin in Transforming Growth Factor-β Signaling and Adipose Browning: Potential for Therapeutic Intervention in Obesity Related Metabolic Disorders
inferred← citeshttps://doi.org/10.3389/fendo.2022.892672openalex-snapshot
Contribution of Liver and Pancreatic Islet Crosstalk to β-Cell Function/Dysfunction in the Presence of Fatty Liver
inferred← citeshttps://doi.org/10.3390/ijms23169427openalex-snapshot
Resistance Training Improves Beta Cell Glucose Sensing and Survival in Diabetic Models
inferred← citeshttps://doi.org/10.3390/jcm10030385openalex-snapshot
Hepatokines as a Molecular Transducer of Exercise
inferred← citeshttps://doi.org/10.3390/jpm14050487openalex-snapshot
Follistatin as a Potential Biomarker for Identifying Metabolically Healthy and Unhealthy Obesity: A Cross-Sectional Study
inferred← citeshttps://doi.org/10.3390/nu10010075openalex-snapshot
Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice
inferred← citeshttps://doi.org/10.3390/nu18030509openalex-snapshot
Adipo-Myokine Modulation in Obesity: Integrative Effects of Spinach Thylakoids and Functional Training in Men with Obesity: A Randomized Controlled Clinical Trial
inferred← citeshttps://doi.org/10.5352/jls.2021.31.8.699openalex-snapshot
Effect of Scytosiphon lomentaria Ethanol Extracts on Myostatin Activity and Zebrafish Obesity Induced by High Feeding
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