On the public citation graph

Inactivation of hCDC4 can cause chromosomal instability

https://doi.org/10.1038/nature02313
0 signed · 543 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1097-0142(19810801)48:3<745::aid-cncr2820480314>3.0.co;2-7openalex-snapshot
A Neoplastic Epithelial Duct Cell Line Established From An Irradiated Human Salivary Gland
inferredcites →https://doi.org/10.1002/elps.1150181505openalex-snapshot
SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling
inferredcites →https://doi.org/10.1016/0165-7992(89)90115-2openalex-snapshot
Acentric chromosomal fragments and micronuclei: the time-displacement factor
inferredcites →https://doi.org/10.1016/s0092-8674(01)00340-3openalex-snapshot
Securin Is Required for Chromosomal Stability in Human Cells
inferredcites →https://doi.org/10.1016/s0092-8674(03)00034-5openalex-snapshot
Structural Basis for Phosphodependent Substrate Selection and Orientation by the SCFCdc4 Ubiquitin Ligase
inferredcites →https://doi.org/10.1016/s0960-9822(00)80021-4openalex-snapshot
A family of mammalian F-box proteins
inferredcites →https://doi.org/10.1016/s0960-9822(98)70156-3openalex-snapshot
Histone–GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells
inferredcites →https://doi.org/10.1038/25292openalex-snapshot
Genetic instabilities in human cancers
inferredcites →https://doi.org/10.1038/32688openalex-snapshot
Mutations of mitotic checkpoint genes in human cancers
inferredcites →https://doi.org/10.1038/35095068openalex-snapshot
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines
inferredcites →https://doi.org/10.1038/35095076openalex-snapshot
Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line
inferredcites →https://doi.org/10.1038/35095157openalex-snapshot
Archipelago of destruction
inferredcites →https://doi.org/10.1038/35107009openalex-snapshot
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
inferredcites →https://doi.org/10.1038/386623a0openalex-snapshot
Genetic instability in colorectal cancers
inferredcites →https://doi.org/10.1038/45836openalex-snapshot
Deregulated cyclin E induces chromosome instability
inferredcites →https://doi.org/10.1038/ng0796-343openalex-snapshot
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
inferredcites →https://doi.org/10.1038/nrc1165openalex-snapshot
The significance of unstable chromosomes in colorectal cancer
inferredcites →https://doi.org/10.1038/nrc1170openalex-snapshot
Genomic instability — the engine of tumorigenesis?
inferredcites →https://doi.org/10.1073/pnas.012679099openalex-snapshot
Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC
inferredcites →https://doi.org/10.1073/pnas.202617399openalex-snapshot
The role of chromosomal instability in tumor initiation
inferredcites →https://doi.org/10.1126/science.1065203openalex-snapshot
Phosphorylation-Dependent Ubiquitination of Cyclin E by the SCF Fbw7 Ubiquitin Ligase
inferredcites →https://doi.org/10.1126/science.1066237openalex-snapshot
Order from Destruction
inferredcites →https://doi.org/10.1126/science.1082596openalex-snapshot
Mutational Analysis of the Tyrosine Kinome in Colorectal Cancers
inferredcites →https://doi.org/10.1128/mcb.19.8.5512openalex-snapshot
Cdc4, a Protein Required for the Onset of S Phase, Serves an Essential Function during G 2 /M Transition in Saccharomyces cerevisiae

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3281653openalex-extracted
LSD1 Destabilizes FBXW7 Independent of Its Demethylase Activity
inferred← citeshttps://doi.org/10.1002/1878-0261.12012openalex-snapshot
Multiregion ultra‐deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer
inferred← citeshttps://doi.org/10.1002/1878-0261.12200openalex-snapshot
FBXW 7 deletion contributes to lung tumor development and confers resistance to gefitinib therapy
inferred← citeshttps://doi.org/10.1002/1878-0261.12307openalex-snapshot
Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents
inferred← citeshttps://doi.org/10.1002/1878-0261.13537openalex-snapshot
Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7
inferred← citeshttps://doi.org/10.1002/9780470025079.chap07.pub2openalex-snapshot
Genomic Instability and DNA Repair
inferred← citeshttps://doi.org/10.1002/9781118512074.ch31openalex-snapshot
Neoplasia of the Gastrointestinal Tract
inferred← citeshttps://doi.org/10.1002/advs.202404718openalex-snapshot
The FBXW7‐RPAP2 Axis Controls the Growth of Hepatocellular Carcinoma Cells and Determines the Fate of Liver Cell Differentiation
inferred← citeshttps://doi.org/10.1002/ange.202512791openalex-snapshot
Neo‐Cysteine Molecular Glues for Targeting Mutated SMAD4 Protein
inferred← citeshttps://doi.org/10.1002/anie.202512791openalex-snapshot
Neo‐Cysteine Molecular Glues for Targeting Mutated SMAD4 Protein
inferred← citeshttps://doi.org/10.1002/bies.201100101openalex-snapshot
The two faces of FBW7 in cancer drug resistance
inferred← citeshttps://doi.org/10.1002/cbin.10713openalex-snapshot
Skeletal muscle atrophy is induced by Fbxw7β via atrogene upregulation
inferred← citeshttps://doi.org/10.1002/cbin.11396openalex-snapshot
Tumor‐suppressor Fbxw7 targets SIK2 for degradation to interfere with TORC2‐AKT signaling in pancreatic cancer
inferred← citeshttps://doi.org/10.1002/cnr2.1822openalex-snapshot
Chromosomal instability and its effect on cell lines
inferred← citeshttps://doi.org/10.1002/dc.21297openalex-snapshot
Micronucleus in atypical urothelial cells
inferred← citeshttps://doi.org/10.1002/gcc.20351openalex-snapshot
Contribution of theBOP1 gene, located on 8q24, to colorectal tumorigenesis
inferred← citeshttps://doi.org/10.1002/ijc.24879openalex-snapshot
Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: Clinical significance
inferred← citeshttps://doi.org/10.1002/ijc.25529openalex-snapshot
Somatic mutations and germline sequence variants in patients with familial colorectal cancer
inferred← citeshttps://doi.org/10.1002/ijc.29168openalex-snapshot
The sensitivity of gastric cancer to trastuzumab is regulated by the mi R ‐223/ FBXW 7 pathway
inferred← citeshttps://doi.org/10.1002/ijc.31736openalex-snapshot
Clinical significance and biological function of WD repeat domain 54 as an oncogene in colorectal cancer
inferred← citeshttps://doi.org/10.1002/jcp.24812openalex-snapshot
Isoform‐Specific SCFFbw7 Ubiquitination Mediates Differential Regulation of PGC‐1α
inferred← citeshttps://doi.org/10.1002/path.2874openalex-snapshot
FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development
inferred← citeshttps://doi.org/10.1002/path.4004openalex-snapshot
CDC4/FBXW7 and the ‘just enough’ model of tumourigenesis
inferred← citeshttps://doi.org/10.1002/path.4139openalex-snapshot
Use of multivariate analysis to suggest a new molecular classification of colorectal cancer
inferred← citeshttps://doi.org/10.1002/path.4310openalex-snapshot
Whole‐exome sequencing of pancreatic neoplasms with acinar differentiation
inferred← citeshttps://doi.org/10.1002/pmic.200401307openalex-snapshot
Proteomic identification of differentially‐expressed genes in human gastric carcinomas
inferred← citeshttps://doi.org/10.1002/pmic.200800121openalex-snapshot
Chromosomal and proteome analysis of a new T24‐based cell line model for aggressive bladder cancer
inferred← citeshttps://doi.org/10.1002/stem.2668openalex-snapshot
Colorectal Cancer Stem Cells Acquire Chemoresistance Through the Upregulation of F-Box/WD Repeat-Containing Protein 7 and the Consequent Degradation of c-Myc
inferred← citeshttps://doi.org/10.1007/978-0-387-09568-4_3openalex-snapshot
The Chromosomal-Instability Pathway and APC Gene Mutation in Colorectal Cancer
inferred← citeshttps://doi.org/10.1007/978-0-387-69076-6_14openalex-snapshot
The Kinetochore-Cancer Connection
inferred← citeshttps://doi.org/10.1007/978-0-387-74039-3_4openalex-snapshot
Cell Cycle Deregulation in Breast Cancer: Insurmountable Chemoresistance or Achilles’ Heel?
inferred← citeshttps://doi.org/10.1007/978-1-4614-8412-7_10openalex-snapshot
Copy-Number Alterations in the Colorectal Cancer Genome
inferred← citeshttps://doi.org/10.1007/978-1-4614-8412-7_2openalex-snapshot
Molecular Mechanisms of Colorectal Carcinogenesis
inferred← citeshttps://doi.org/10.1007/978-1-60761-178-3_9openalex-snapshot
G1 Phase Cyclins in Cancer Development and Progression
inferred← citeshttps://doi.org/10.1007/978-1-60761-849-2_7openalex-snapshot
Micronucleus Assay and Labeling of Centromeres with FISH Technique
inferred← citeshttps://doi.org/10.1007/978-3-030-38266-7_1openalex-snapshot
Ubiquitin-Regulated Cell Proliferation and Cancer
inferred← citeshttps://doi.org/10.1007/978-3-030-64668-4_7openalex-snapshot
Diagnosis of Colorectal Cancer Using Molecular Techniques
inferred← citeshttps://doi.org/10.1007/978-3-319-12136-9_9openalex-snapshot
Synthetic Genetic Approaches in Colorectal Cancer: Exploiting and Targeting Genome Instability
inferred← citeshttps://doi.org/10.1007/978-3-319-20291-4_5openalex-snapshot
Causes of Chromosomal Instability
inferred← citeshttps://doi.org/10.1007/978-3-540-28656-1_52openalex-snapshot
Genetic Pathways in Pancreatic Tumorigenesis
inferred← citeshttps://doi.org/10.1007/978-90-481-2561-6_3openalex-snapshot
An Oncogene-Induced DNA Replication Stress Model for Cancer Development
inferred← citeshttps://doi.org/10.1007/978-90-481-8833-8openalex-snapshot
Metastasis of Colorectal Cancer
inferred← citeshttps://doi.org/10.1007/978-90-481-8833-8_3openalex-snapshot
The Genetics of Colorectal Cancer
inferred← citeshttps://doi.org/10.1007/978-981-10-6955-0_22openalex-snapshot
Cyclin E Deregulation and Genomic Instability
inferred← citeshttps://doi.org/10.1007/978-981-13-5877-7_4openalex-snapshot
Predicting E3 Ubiquitin Ligases as Possible Promising Biomarkers for Brain Tumors
inferred← citeshttps://doi.org/10.1007/978-981-15-1025-0_10openalex-snapshot
Knockout Mouse Models Provide Insight into the Biological Functions of CRL1 Components
inferred← citeshttps://doi.org/10.1007/978-981-15-1025-0_9openalex-snapshot
Targeting SCF E3 Ligases for Cancer Therapies
inferred← citeshttps://doi.org/10.1007/b136681openalex-snapshot
The ubiquitin-proteasome pathway in cell cycle control
inferred← citeshttps://doi.org/10.1007/s00018-023-05019-9openalex-snapshot
E3-ubiquitin ligase, FBXW7 regulates mitotic progression by targeting BubR1 for ubiquitin-mediated degradation
inferred← citeshttps://doi.org/10.1007/s00204-011-0691-4openalex-snapshot
The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance
inferred← citeshttps://doi.org/10.1007/s00384-010-1022-6openalex-snapshot
Stem cells in colon cancer. A new era in cancer theory begins
inferred← citeshttps://doi.org/10.1007/s00412-008-0169-1openalex-snapshot
Classification of chromosome segregation errors in cancer
inferred← citeshttps://doi.org/10.1007/s10441-008-9047-8openalex-snapshot
Beyond the Oncogene Paradigm: Understanding Complexity in Cancerogenesis
inferred← citeshttps://doi.org/10.1007/s10549-007-9623-7openalex-snapshot
FBXW7 and DNA copy number instability
inferred← citeshttps://doi.org/10.1007/s10555-005-1581-0openalex-snapshot
De-regulation of ubiquitin-dependent proteolysis and the pathogenesis of malignant melanoma
inferred← citeshttps://doi.org/10.1007/s10555-011-9330-zopenalex-snapshot
Role of the ubiquitin ligase Fbw7 in cancer progression
inferred← citeshttps://doi.org/10.1007/s10577-015-9511-7openalex-snapshot
Ubiquitin, the centrosome, and chromosome segregation
inferred← citeshttps://doi.org/10.1007/s11888-006-0004-0openalex-snapshot
Genomic instability and colorectal cancer
inferred← citeshttps://doi.org/10.1007/s11888-007-0001-yopenalex-snapshot
Mitotic origins of chromosomal instability in colorectal cancer
inferred← citeshttps://doi.org/10.1007/s12185-024-03880-3openalex-snapshot
Clinical significance of NOTCH1 and FBXW7 alterations in adult T-cell leukemia/lymphoma
inferred← citeshttps://doi.org/10.1007/s12272-020-01281-8openalex-snapshot
Ubiquitin–proteasome system (UPS) as a target for anticancer treatment
inferred← citeshttps://doi.org/10.1007/s13277-015-4375-1openalex-snapshot
Increased expression of ESCO1 is correlated with poor patient survival and its role in human bladder cancer
inferred← citeshttps://doi.org/10.1007/s13277-016-5217-5openalex-snapshot
Tumor suppressor Fbxw7 antagonizes WNT signaling by targeting β-catenin for degradation in pancreatic cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-382026-6.00015-4openalex-snapshot
The Cell Cycle
inferred← citeshttps://doi.org/10.1016/b978-0-12-803309-8.00027-6openalex-snapshot
Cancer and Genomic Instability
inferred← citeshttps://doi.org/10.1016/b978-0-12-809954-4.00008-6openalex-snapshot
The Cell Cycle
inferred← citeshttps://doi.org/10.1016/b978-0-12-811913-6.00005-9openalex-snapshot
Ubiquitin Mediated Posttranslational Modification of Proteins Involved in Various Signaling Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-323-85679-9.00026-xopenalex-snapshot
Cancer and genomic instability
inferred← citeshttps://doi.org/10.1016/j.abb.2015.07.005openalex-snapshot
The role of Myc and let-7a in glioblastoma, glucose metabolism and response to therapy
inferred← citeshttps://doi.org/10.1016/j.aquatox.2013.10.006openalex-snapshot
Arsenic exposure alters expression of cell cycle and lipid metabolism genes in the liver of adult zebrafish (Danio rerio)
inferred← citeshttps://doi.org/10.1016/j.aquatox.2017.11.001openalex-snapshot
Oxidative stress, cell cycle arrest, DNA damage and apoptosis in adult zebrafish (Danio rerio) induced by tris(1,3-dichloro-2-propyl) phosphate
inferred← citeshttps://doi.org/10.1016/j.bbagen.2021.129995openalex-snapshot
Therapeutic targeting of PIM KINASE signaling in cancer therapy: Structural and clinical prospects
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2004.09.027openalex-snapshot
A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2013.02.028openalex-snapshot
The ubiquitin proteasome system — Implications for cell cycle control and the targeted treatment of cancer
inferred← citeshttps://doi.org/10.1016/j.bbcan.2006.08.004openalex-snapshot
Expression and genomic profiling of colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.bbcan.2008.07.007openalex-snapshot
When 2+2=5: The origins and fates of aneuploid and tetraploid cells
inferred← citeshttps://doi.org/10.1016/j.bbcan.2023.189035openalex-snapshot
Role of F-box proteins in human upper gastrointestinal tumors
inferred← citeshttps://doi.org/10.1016/j.bbrc.2006.09.003openalex-snapshot
Expression of mouse Fbxw7 isoforms is regulated in a cell cycle- or p53-dependent manner
inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.01.080openalex-snapshot
The FBXW7 β-form is suppressed in human glioma cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.10.047openalex-snapshot
The methylation status of FBXW7 β-form correlates with histological subtype in human thymoma
inferred← citeshttps://doi.org/10.1016/j.bbrc.2013.03.077openalex-snapshot
Rapamycin inhibits FBXW7 loss-induced epithelial–mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells
inferred← citeshttps://doi.org/10.1016/j.biocel.2005.01.003openalex-snapshot
Chromosome instability in neoplasia: chaotic roots to continuous growth
inferred← citeshttps://doi.org/10.1016/j.biocel.2016.02.005openalex-snapshot
Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteins
inferred← citeshttps://doi.org/10.1016/j.biocel.2021.106152openalex-snapshot
Proline-serine-threonine-repeat region of MDC1 mediates Chk1 phosphorylation and the DNA double-strand break repair
inferred← citeshttps://doi.org/10.1016/j.biochi.2006.07.004openalex-snapshot
Chromosomal changes: induction, detection methods and applicability in human biomonitoring
inferred← citeshttps://doi.org/10.1016/j.cancergencyto.2005.01.009openalex-snapshot
Genome-wide aberrations in pancreatic adenocarcinoma
inferred← citeshttps://doi.org/10.1016/j.cancergencyto.2006.04.007openalex-snapshot
hCDC4 variation in osteosarcoma
inferred← citeshttps://doi.org/10.1016/j.canlet.2008.04.036openalex-snapshot
The Fbxw7/hCdc4 tumor suppressor in human cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2019.04.014openalex-snapshot
Pseudophosphatase STYX promotes tumor growth and metastasis by inhibiting FBXW7 function in colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.ccell.2014.09.013openalex-snapshot
Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities
inferred← citeshttps://doi.org/10.1016/j.ccr.2005.06.005openalex-snapshot
The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
inferred← citeshttps://doi.org/10.1016/j.ccr.2005.06.010openalex-snapshot
A mouse model for cyclin E-dependent genetic instability and tumorigenesis
inferred← citeshttps://doi.org/10.1016/j.ccr.2006.03.030openalex-snapshot
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
inferred← citeshttps://doi.org/10.1016/j.ccr.2013.04.027openalex-snapshot
Epidermal Growth Factor Receptor Potentiates MCM7-Mediated DNA Replication through Tyrosine Phosphorylation of Lyn Kinase in Human Cancers
inferred← citeshttps://doi.org/10.1016/j.ceb.2005.09.012openalex-snapshot
The kinetochore and cancer: what's the connection?
inferred← citeshttps://doi.org/10.1016/j.ceb.2011.11.012openalex-snapshot
Kinetochores and disease: keeping microtubule dynamics in check!
inferred← citeshttps://doi.org/10.1016/j.cell.2006.09.045openalex-snapshot
Deletion of DDB1 in Mouse Brain and Lens Leads to p53-Dependent Elimination of Proliferating Cells
inferred← citeshttps://doi.org/10.1016/j.cell.2007.04.042openalex-snapshot
Suprafacial Orientation of the SCFCdc4 Dimer Accommodates Multiple Geometries for Substrate Ubiquitination
inferred← citeshttps://doi.org/10.1016/j.cell.2013.05.041openalex-snapshot
The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability
inferred← citeshttps://doi.org/10.1016/j.cellsig.2007.12.020openalex-snapshot
Transcriptional repression of c-Jun's E3 ubiquitin ligases contributes to c-Jun induction by UV
inferred← citeshttps://doi.org/10.1016/j.celrep.2012.04.002openalex-snapshot
SCFFbw7 Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.06.101openalex-snapshot
BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.12.032openalex-snapshot
FBXW7 Confers Radiation Survival by Targeting p53 for Degradation
inferred← citeshttps://doi.org/10.1016/j.chom.2013.06.008openalex-snapshot
Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7
inferred← citeshttps://doi.org/10.1016/j.cmet.2005.04.010openalex-snapshot
Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCFFbw7
inferred← citeshttps://doi.org/10.1016/j.cub.2004.04.040openalex-snapshot
The Drosophila F Box Protein Archipelago Regulates dMyc Protein Levels In Vivo
inferred← citeshttps://doi.org/10.1016/j.cub.2004.09.083openalex-snapshot
A Nucleolar Isoform of the Fbw7 Ubiquitin Ligase Regulates c-Myc and Cell Size
inferred← citeshttps://doi.org/10.1016/j.cub.2009.09.055openalex-snapshot
Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability
inferred← citeshttps://doi.org/10.1016/j.cub.2010.01.034openalex-snapshot
Mechanisms of Chromosomal Instability
inferred← citeshttps://doi.org/10.1016/j.devcel.2011.09.014openalex-snapshot
SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation
inferred← citeshttps://doi.org/10.1016/j.ejca.2005.10.034openalex-snapshot
Mutational analysis of the hCDC4 gene in gastric carcinomas
inferred← citeshttps://doi.org/10.1016/j.ejmech.2020.112870openalex-snapshot
Design, synthesis and screening of benzimidazole containing compounds with methoxylated aryl radicals as cytotoxic molecules on (HCT-116) colon cancer cells
inferred← citeshttps://doi.org/10.1016/j.ejmhg.2012.09.001openalex-snapshot
Novel mutation predicted to disrupt SGOL1 protein function
inferred← citeshttps://doi.org/10.1016/j.ejso.2011.08.139openalex-snapshot
Overexpression of cyclin E isoforms correlates with poor prognosis in rectal cancer
inferred← citeshttps://doi.org/10.1016/j.esmoop.2022.100592openalex-snapshot
A phase II study to explore biomarkers for the use of mFOLFOX6/XELOX plus bevacizumab as a first-line chemotherapy in patients with metastatic colorectal cancer (WJOG7612GTR)
inferred← citeshttps://doi.org/10.1016/j.febslet.2011.05.036openalex-snapshot
PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity
inferred← citeshttps://doi.org/10.1016/j.febslet.2012.03.017openalex-snapshot
Tumor suppressor functions of FBW7 in cancer development and progression
inferred← citeshttps://doi.org/10.1016/j.gene.2024.148181openalex-snapshot
FBXW7 polymorphism asserts susceptibility to colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.identj.2022.11.008openalex-snapshot
FBXW7 Enhances Cisplatin-Induced Apoptosis in Oral Cancer Cell Lines
inferred← citeshttps://doi.org/10.1016/j.jbc.2025.111104openalex-snapshot
FBXW7 E3 ligase prevents centriole overduplication by degrading the Plk4 phosphorylated STIL-SAS6 cartwheel assembly
inferred← citeshttps://doi.org/10.1016/j.jtbi.2005.11.012openalex-snapshot
Genetic instability and clonal expansion
inferred← citeshttps://doi.org/10.1016/j.jtbi.2008.05.027openalex-snapshot
A stochastic carcinogenesis model incorporating multiple types of genomic instability fitted to colon cancer data
inferred← citeshttps://doi.org/10.1016/j.leukres.2008.03.040openalex-snapshot
FBXW7 mutation in adult T-cell and B-cell acute lymphocytic leukemias
inferred← citeshttps://doi.org/10.1016/j.molcel.2006.05.020openalex-snapshot
Ubiquitylation of Cyclin E Requires the Sequential Function of SCF Complexes Containing Distinct hCdc4 Isoforms
inferred← citeshttps://doi.org/10.1016/j.molcel.2007.02.022openalex-snapshot
Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
inferred← citeshttps://doi.org/10.1016/j.molcel.2011.08.029openalex-snapshot
DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy
inferred← citeshttps://doi.org/10.1016/j.molcel.2014.09.023openalex-snapshot
SGK3 Mediates INPP4B-Dependent PI3K Signaling in Breast Cancer
inferred← citeshttps://doi.org/10.1016/j.molcel.2015.12.010openalex-snapshot
FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4
inferred← citeshttps://doi.org/10.1016/j.molcel.2017.10.018openalex-snapshot
NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis
inferred← citeshttps://doi.org/10.1016/j.molcel.2023.07.026openalex-snapshot
FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress
inferred← citeshttps://doi.org/10.1016/j.mrfmmm.2005.03.031openalex-snapshot
Moderate acute intake of de-alcoholised red wine, but not alcohol, is protective against radiation-induced DNA damage ex vivo—Results of a comparative in vivo intervention study in younger men
inferred← citeshttps://doi.org/10.1016/j.mrfmmm.2006.05.028openalex-snapshot
Cytokinesis-block micronucleus assay evolves into a “cytome” assay of chromosomal instability, mitotic dysfunction and cell death
inferred← citeshttps://doi.org/10.1016/j.mrgentox.2006.04.008openalex-snapshot
The in vitro micronucleus test: From past to future
inferred← citeshttps://doi.org/10.1016/j.mrgentox.2007.10.020openalex-snapshot
Mitotic checkpoints and the maintenance of the chromosome karyotype
inferred← citeshttps://doi.org/10.1016/j.mrrev.2012.12.001openalex-snapshot
Non-targeted effects of ionising radiation—Implications for low dose risk
inferred← citeshttps://doi.org/10.1016/j.mrrev.2016.03.003openalex-snapshot
Biomonitoring of humans exposed to arsenic, chromium, nickel, vanadium, and complex mixtures of metals by using the micronucleus test in lymphocytes
inferred← citeshttps://doi.org/10.1016/j.neo.2016.08.009openalex-snapshot
Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation
inferred← citeshttps://doi.org/10.1016/j.neo.2017.02.012openalex-snapshot
Chromosomal Instability in Gastric Cancer Biology
inferred← citeshttps://doi.org/10.1016/j.otohns.2005.09.003openalex-snapshot
Genomic Instability in the Progression of Sporadic Nasopharyngeal Carcinoma
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2019.02.006openalex-snapshot
Targeting the CINful genome: Strategies to overcome tumor heterogeneity
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2023.04.002openalex-snapshot
Colon cancer transcriptome
inferred← citeshttps://doi.org/10.1016/j.semcancer.2004.09.002openalex-snapshot
Connecting mitotic instability and chromosome aberrations in cancer—can telomeres bridge the gap?
inferred← citeshttps://doi.org/10.1016/j.semcancer.2004.09.004openalex-snapshot
Mechanisms leading to chromosomal instability
inferred← citeshttps://doi.org/10.1016/j.semcancer.2004.09.007openalex-snapshot
Can chromosomal instability initiate tumorigenesis?
inferred← citeshttps://doi.org/10.1016/j.semcancer.2004.09.008openalex-snapshot
The evolutionary origin of genetic instability in cancer development
inferred← citeshttps://doi.org/10.1016/j.semcancer.2015.09.005openalex-snapshot
Regulating Fbw7 on the road to cancer
inferred← citeshttps://doi.org/10.1016/j.semcancer.2015.09.006openalex-snapshot
Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance
inferred← citeshttps://doi.org/10.1016/j.semcancer.2015.09.015openalex-snapshot
Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis
inferred← citeshttps://doi.org/10.1016/j.semcdb.2005.02.010openalex-snapshot
Regulation of the cell cycle by SCF-type ubiquitin ligases
inferred← citeshttps://doi.org/10.1016/j.soc.2009.08.004openalex-snapshot
Overview of Colorectal Cancer Genetics
inferred← citeshttps://doi.org/10.1016/j.surg.2009.09.037openalex-snapshot
Gene-expression phenotypes for vascular invasiveness of hepatocellular carcinomas
inferred← citeshttps://doi.org/10.1016/j.tig.2007.11.006openalex-snapshot
Defining ‘chromosomal instability’
inferred← citeshttps://doi.org/10.1016/j.tree.2007.12.007openalex-snapshot
Evolutionary dynamics of cancer
inferred← citeshttps://doi.org/10.1016/j.ydbio.2007.10.002openalex-snapshot
The Drosophila F-box protein Archipelago controls levels of the Trachealess transcription factor in the embryonic tracheal system
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.04.014openalex-snapshot
Developmental downregulation of Xenopus cyclin E is phosphorylation and nuclear import dependent and is mediated by ubiquitination
inferred← citeshttps://doi.org/10.1016/j.yexcr.2005.02.017openalex-snapshot
A temperature-sensitive mutation in the WD repeat-containing protein Smu1 is related to maintenance of chromosome integrity
inferred← citeshttps://doi.org/10.1016/j.yexcr.2008.11.017openalex-snapshot
SCFFbxw7/hCdc4 targets cyclin E2 for ubiquitin-dependent proteolysis
inferred← citeshttps://doi.org/10.1016/j.ygyno.2005.04.007openalex-snapshot
Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer
inferred← citeshttps://doi.org/10.1016/s0065-230x(10)07006-5openalex-snapshot
MYC in Oncogenesis and as a Target for Cancer Therapies
inferred← citeshttps://doi.org/10.1016/s0140-6736(05)17706-xopenalex-snapshot
Colorectal cancer
inferred← citeshttps://doi.org/10.1016/s1359-6349(08)71417-4openalex-snapshot
An oncogene-induced DNA replication stress model for human cancer development
inferred← citeshttps://doi.org/10.1017/cbo9780511979811.008openalex-snapshot
Events responsible for aberrant genetic and epigenetic codes in cancer
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b01346openalex-snapshot
Regulating the Master Regulator: Controlling Ubiquitination by Thinking Outside the Active Site
inferred← citeshttps://doi.org/10.1038/ajg.2009.85openalex-snapshot
Metaplastic Esophageal Columnar Epithelium Without Goblet Cells Shows DNA Content Abnormalities Similar to Goblet Cell–Containing Epithelium
inferred← citeshttps://doi.org/10.1038/bjc.2017.277openalex-snapshot
RNAi screen reveals synthetic lethality between cyclin G-associated kinase and FBXW7 by inducing aberrant mitoses
inferred← citeshttps://doi.org/10.1038/cr.2013.67openalex-snapshot
Regulation of APCCdh1 E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7
inferred← citeshttps://doi.org/10.1038/emboj.2009.14openalex-snapshot
An unsteady scaffold for Myc
inferred← citeshttps://doi.org/10.1038/mtm.2016.24openalex-snapshot
Fbxw7-associated drug resistance is reversed by induction of terminal differentiation in murine intestinal organoid culture
inferred← citeshttps://doi.org/10.1038/nature03099openalex-snapshot
Aneuploidy and cancer
inferred← citeshttps://doi.org/10.1038/nature03155openalex-snapshot
Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene
inferred← citeshttps://doi.org/10.1038/nature03482openalex-snapshot
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
inferred← citeshttps://doi.org/10.1038/nature03958openalex-snapshot
Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines
inferred← citeshttps://doi.org/10.1038/nature05886openalex-snapshot
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
inferred← citeshttps://doi.org/10.1038/nbt.1646openalex-snapshot
An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase
inferred← citeshttps://doi.org/10.1038/nbt0505-535openalex-snapshot
The Human Cancer Genome Project—one more misstep in the war on cancer
inferred← citeshttps://doi.org/10.1038/ncb1809openalex-snapshot
Genome stability is ensured by temporal control of kinetochore–microtubule dynamics
inferred← citeshttps://doi.org/10.1038/ncb2463openalex-snapshot
Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma
inferred← citeshttps://doi.org/10.1038/ncb3121openalex-snapshot
FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification
inferred← citeshttps://doi.org/10.1038/ncomms1975openalex-snapshot
Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway
inferred← citeshttps://doi.org/10.1038/ng.2981openalex-snapshot
Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins
inferred← citeshttps://doi.org/10.1038/ng.491openalex-snapshot
Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies
inferred← citeshttps://doi.org/10.1038/nm1087openalex-snapshot
Cancer genes and the pathways they control
inferred← citeshttps://doi.org/10.1038/nm1266openalex-snapshot
Genomic instability in laminopathy-based premature aging
inferred← citeshttps://doi.org/10.1038/nmeth1081openalex-snapshot
Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection
inferred← citeshttps://doi.org/10.1038/nprot.2007.77openalex-snapshot
Cytokinesis-block micronucleus cytome assay
inferred← citeshttps://doi.org/10.1038/nrc.2017.105openalex-snapshot
Ubiquitin ligases in oncogenic transformation and cancer therapy
inferred← citeshttps://doi.org/10.1038/nrc1295openalex-snapshot
Dynamics of cancer progression
inferred← citeshttps://doi.org/10.1038/nrc1327openalex-snapshot
All about E
inferred← citeshttps://doi.org/10.1038/nrc1881openalex-snapshot
Ubiquitin ligases: cell-cycle control and cancer
inferred← citeshttps://doi.org/10.1038/nrc2290openalex-snapshot
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
inferred← citeshttps://doi.org/10.1038/nrc2645openalex-snapshot
Genetic prognostic and predictive markers in colorectal cancer
inferred← citeshttps://doi.org/10.1038/nrc2916openalex-snapshot
Harnessing transposons for cancer gene discovery
inferred← citeshttps://doi.org/10.1038/nrc3468openalex-snapshot
In the wrong place at the wrong time: does cyclin mislocalization drive oncogenic transformation?
inferred← citeshttps://doi.org/10.1038/nrd2056openalex-snapshot
Drug discovery in the ubiquitin–proteasome system
inferred← citeshttps://doi.org/10.1038/nrm1960openalex-snapshot
Reading protein modifications with interaction domains
inferred← citeshttps://doi.org/10.1038/onc.2008.77openalex-snapshot
Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy
inferred← citeshttps://doi.org/10.1038/onc.2009.477openalex-snapshot
p53 suppresses structural chromosome instability after mitotic arrest in human cells
inferred← citeshttps://doi.org/10.1038/onc.2010.222openalex-snapshot
The ubiquitous nature of cancer: the role of the SCFFbw7 complex in development and transformation
inferred← citeshttps://doi.org/10.1038/onc.2010.278openalex-snapshot
Tumor suppressor Fbxw7 regulates TGFβ signaling by targeting TGIF1 for degradation
inferred← citeshttps://doi.org/10.1038/onc.2011.339openalex-snapshot
PP2A-B56α controls oncogene-induced senescence in normal and tumor human melanocytic cells
showing the first 200 of 519
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.