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An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/0968-0004(96)30009-1openalex-snapshot
The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB
inferredcites →https://doi.org/10.1016/j.cell.2004.12.012openalex-snapshot
Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1
inferredcites →https://doi.org/10.1016/s0896-6273(01)00371-3openalex-snapshot
Regulation of Neuronal Traits by a Novel Transcriptional Complex
inferredcites →https://doi.org/10.1016/s0969-2126(99)80037-9openalex-snapshot
A 30 Å long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase
inferredcites →https://doi.org/10.1016/s1097-2765(02)00634-2openalex-snapshot
Essential Role for the SANT Domain in the Functioning of Multiple Chromatin Remodeling Enzymes
inferredcites →https://doi.org/10.1016/s1097-2765(03)00424-6openalex-snapshot
Regulation of BRCC, a Holoenzyme Complex Containing BRCA1 and BRCA2, by a Signalosome-like Subunit and Its Role in DNA Repair
inferredcites →https://doi.org/10.1038/nature03120openalex-snapshot
The Microprocessor complex mediates the genesis of microRNAs
inferredcites →https://doi.org/10.1073/pnas.112008599openalex-snapshot
A core–BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes
inferredcites →https://doi.org/10.1073/pnas.1633804100openalex-snapshot
Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures
inferredcites →https://doi.org/10.1073/pnas.96.17.9873openalex-snapshot
CoREST: A functional corepressor required for regulation of neural-specific gene expression
inferredcites →https://doi.org/10.1073/pnas.98.4.1454openalex-snapshot
CoREST is an integral component of the CoREST- human histone deacetylase complex
inferredcites →https://doi.org/10.1074/jbc.275.13.9461openalex-snapshot
The Co-repressor mSin3A Is a Functional Component of the REST-CoREST Repressor Complex
inferredcites →https://doi.org/10.1074/jbc.m007372200openalex-snapshot
Stable Histone Deacetylase Complexes Distinguished by the Presence of SANT Domain Proteins CoREST/kiaa0071 and Mta-L1
inferredcites →https://doi.org/10.1074/jbc.m108601200openalex-snapshot
The SANT Domain of Ada2 Is Required for Normal Acetylation of Histones by the Yeast SAGA Complex
inferredcites →https://doi.org/10.1074/jbc.m205691200openalex-snapshot
REST Repression of Neuronal Genes Requires Components of the hSWI·SNF Complex
inferredcites →https://doi.org/10.1074/jbc.m208992200openalex-snapshot
A Candidate X-linked Mental Retardation Gene Is a Component of a New Family of Histone Deacetylase-containing Complexes
inferredcites →https://doi.org/10.1093/emboj/cdg326openalex-snapshot
A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation
inferredcites →https://doi.org/10.1093/emboj/cdg582openalex-snapshot
Isolation of human NURF: a regulator of Engrailed gene expression
inferredcites →https://doi.org/10.1126/science.1076469openalex-snapshot
Corepressor-Dependent Silencing of Chromosomal Regions Encoding Neuronal Genes
inferredcites →https://doi.org/10.1128/mcb.21.18.6091-6101.2001openalex-snapshot
The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3
inferredcites →https://doi.org/10.1128/mcb.23.1.250-258.2003openalex-snapshot
Human MI-ER1 Alpha and Beta Function as Transcriptional Repressors by Recruitment of Histone Deacetylase 1 to Their Conserved ELM2 Domain
inferredcites →https://doi.org/10.1128/mcb.23.3.1025-1033.2003openalex-snapshot
Interaction of Histone Acetylases and Deacetylases In Vivo
inferredcites →https://doi.org/10.1523/jneurosci.0238-04.2004openalex-snapshot
A Conserved Role But Different Partners for the Transcriptional Corepressor CoREST in Fly and Mammalian Nervous System Formation
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inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.11.066openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.05.056openalex-snapshot
Esco2 is a novel corepressor that associates with various chromatin modifying enzymes
inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.09.149openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.biocel.2007.01.025openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.bioorg.2020.103808openalex-snapshot
New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.01.055openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113934openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.blre.2016.02.002openalex-snapshot
Epigenetics: A primer for clinicians
inferred← citeshttps://doi.org/10.1016/j.bmc.2016.12.033openalex-snapshot
Activation of lysine-specific demethylase 1 inhibitor peptide by redox-controlled cleavage of a traceless linker
inferred← citeshttps://doi.org/10.1016/j.bmc.2018.10.037openalex-snapshot
Design, synthesis and in vitro evaluation of stilbene derivatives as novel LSD1 inhibitors for AML therapy
inferred← citeshttps://doi.org/10.1016/j.brainres.2011.12.011openalex-snapshot
Overexpression of either lysine-specific demethylase-1 or CLOCK, but not Co-Rest, improves long-term expression from a modified neurofilament promoter, in a helper virus-free HSV-1 vector system
inferred← citeshttps://doi.org/10.1016/j.cancergen.2014.11.001openalex-snapshot
The role of the histone demethylase KDM4A in cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2016.02.004openalex-snapshot
The histone demethylase LSD1 is a novel oncogene and therapeutic target in oral cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2017.03.038openalex-snapshot
Targeting KDM1A attenuates Wnt/β-catenin signaling pathway to eliminate sorafenib-resistant stem-like cells in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1016/j.canlet.2024.217093openalex-snapshot
Targeting LSD1 in cancer: Molecular elucidation and recent advances
inferred← citeshttps://doi.org/10.1016/j.cbpa.2007.07.014openalex-snapshot
LSD1 and the chemistry of histone demethylation
inferred← citeshttps://doi.org/10.1016/j.cbpa.2012.09.015openalex-snapshot
Mechanisms of human histone and nucleic acid demethylases
inferred← citeshttps://doi.org/10.1016/j.cbpa.2021.02.018openalex-snapshot
Structures of chromatin modulators in complex with nucleosome
inferred← citeshttps://doi.org/10.1016/j.ccell.2019.09.005openalex-snapshot
Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
inferred← citeshttps://doi.org/10.1016/j.ccr.2012.03.014openalex-snapshot
The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells
inferred← citeshttps://doi.org/10.1016/j.ceb.2007.09.011openalex-snapshot
Signaling and epigenetic regulation of pituitary development
inferred← citeshttps://doi.org/10.1016/j.ceb.2008.03.004openalex-snapshot
Mechanisms involved in the regulation of histone lysine demethylases
inferred← citeshttps://doi.org/10.1016/j.cell.2005.08.023openalex-snapshot
Nuclear Reprogramming by Human Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1016/j.cell.2006.03.028openalex-snapshot
Reversal of Histone Lysine Trimethylation by the JMJD2 Family of Histone Demethylases
inferred← citeshttps://doi.org/10.1016/j.cell.2006.12.038openalex-snapshot
Histone Methylation-Dependent Mechanisms Impose Ligand Dependency for Gene Activation by Nuclear Receptors
inferred← citeshttps://doi.org/10.1016/j.cell.2007.01.017openalex-snapshot
Visualizing the Histone Code on LSD1
inferred← citeshttps://doi.org/10.1016/j.cell.2007.02.004openalex-snapshot
Physical and Functional Association of a Trimethyl H3K4 Demethylase and Ring6a/MBLR, a Polycomb-like Protein
inferred← citeshttps://doi.org/10.1016/j.cell.2007.02.005openalex-snapshot
Chromatin Modifications and Their Function
inferred← citeshttps://doi.org/10.1016/j.cell.2007.02.013openalex-snapshot
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
inferred← citeshttps://doi.org/10.1016/j.cell.2007.11.005openalex-snapshot
SnapShot: Histone-Modifying Enzymes
inferred← citeshttps://doi.org/10.1016/j.cell.2009.02.015openalex-snapshot
A C. elegans LSD1 Demethylase Contributes to Germline Immortality by Reprogramming Epigenetic Memory
inferred← citeshttps://doi.org/10.1016/j.cell.2009.05.050openalex-snapshot
LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer
inferred← citeshttps://doi.org/10.1016/j.cell.2025.02.023openalex-snapshot
20 years of histone lysine demethylases: From discovery to the clinic and beyond
inferred← citeshttps://doi.org/10.1016/j.cellsig.2026.112919openalex-snapshot
Functional interplay between LSD1 and HDAC6 supports malignant phenotypes in breast cancer models and is associated with notch-related protein changes
inferred← citeshttps://doi.org/10.1016/j.celrep.2014.01.022openalex-snapshot
TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres
inferred← citeshttps://doi.org/10.1016/j.celrep.2014.06.035openalex-snapshot
Silencing of the DNA Mismatch Repair Gene MLH1 Induced by Hypoxic Stress in a Pathway Dependent on the Histone Demethylase LSD1
inferred← citeshttps://doi.org/10.1016/j.celrep.2014.11.008openalex-snapshot
Lysine-Specific Demethylase 1 Has Dual Functions as a Major Regulator of Androgen Receptor Transcriptional Activity
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.05.050openalex-snapshot
MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.09.053openalex-snapshot
Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.03.012openalex-snapshot
Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.03.061openalex-snapshot
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.01.091openalex-snapshot
Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.03.080openalex-snapshot
Integrative Modeling of a Sin3/HDAC Complex Sub-structure
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.115213openalex-snapshot
Coordinated neuron-specific splicing events restrict nucleosome engagement of the LSD1 histone demethylase complex
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115951openalex-snapshot
Non-canonical activating roles of RCoR2 sustain transcription in adrenergic neuroblastoma
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117293openalex-snapshot
RLF/ZFP292 stabilize CoREST-linked LSD1 engagement at bivalent promoters to safeguard pluripotency
inferred← citeshttps://doi.org/10.1016/j.chembiol.2006.05.004openalex-snapshot
Histone H3 Lysine 4 Demethylation Is a Target of Nonselective Antidepressive Medications
inferred← citeshttps://doi.org/10.1016/j.coi.2006.01.012openalex-snapshot
Lysine methylation and ‘signaling memory’
inferred← citeshttps://doi.org/10.1016/j.conb.2017.12.008openalex-snapshot
REST, a master transcriptional regulator in neurodegenerative disease
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2014.12.016openalex-snapshot
New perspectives in the treatment of adult medulloblastoma in the era of molecular oncology
inferred← citeshttps://doi.org/10.1016/j.ctrv.2013.05.009openalex-snapshot
The promise and failures of epigenetic therapies for cancer treatment
inferred← citeshttps://doi.org/10.1016/j.cub.2007.03.068openalex-snapshot
Mutation of Drosophila Lsd1 Disrupts H3-K4 Methylation, Resulting in Tissue-Specific Defects during Development
inferred← citeshttps://doi.org/10.1016/j.cub.2010.06.037openalex-snapshot
Transcriptional Repression: Conserved and Evolved Features
inferred← citeshttps://doi.org/10.1016/j.devcel.2021.09.001openalex-snapshot
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
inferred← citeshttps://doi.org/10.1016/j.ejcb.2010.01.004openalex-snapshot
LSD1 is required for chromosome segregation during mitosis
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113453openalex-snapshot
Design, synthesis, and biological evaluation of novel dual inhibitors targeting lysine specific demethylase 1 (LSD1) and histone deacetylases (HDAC) for treatment of gastric cancer
inferred← citeshttps://doi.org/10.1016/j.exphem.2022.03.003openalex-snapshot
Epigenetic maintenance strategies after allogeneic stem cell transplantation in acute myeloid leukemia
inferred← citeshttps://doi.org/10.1016/j.febslet.2006.04.065openalex-snapshot
A component of BRAF‐HDAC complex, BHC80, is required for neonatal survival in mice
inferred← citeshttps://doi.org/10.1016/j.febslet.2015.07.028openalex-snapshot
A rationally‐designed chimeric KDM1A/KDM1B histone demethylase tower domain deletion mutant retaining enzymatic activity
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2013.01.124openalex-snapshot
Epigenetic disorders and male subfertility
inferred← citeshttps://doi.org/10.1016/j.fertnstert.2013.11.033openalex-snapshot
Overexpression of lysine-specific demethylase 1 in ovarian endometriomas and its inhibition reduces cellular proliferation, cell cycle progression, and invasiveness
inferred← citeshttps://doi.org/10.1016/j.gde.2006.02.015openalex-snapshot
Histone modifications: signalling receptors and potential elements of a heritable epigenetic code
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.08.221openalex-snapshot
The R251Q mutation of LSD1 promotes invasion and migration of luminal breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.126801openalex-snapshot
Neddylation-dependent LSD1 destabilization inhibits the stemness and chemoresistance of gastric cancer
inferred← citeshttps://doi.org/10.1016/j.ijdevneu.2016.12.006openalex-snapshot
SFPQ associates to LSD1 and regulates the migration of newborn pyramidal neurons in the developing cerebral cortex
inferred← citeshttps://doi.org/10.1016/j.jbc.2024.107881openalex-snapshot
Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis
inferred← citeshttps://doi.org/10.1016/j.jhepr.2020.100177openalex-snapshot
Our emerging understanding of the roles of long non-coding RNAs in normal liver function, disease, and malignancy
inferred← citeshttps://doi.org/10.1016/j.jlr.2024.100513openalex-snapshot
Histone demethylase KDM1A promotes hepatic steatosis and inflammation by increasing chromatin accessibility in NAFLD
inferred← citeshttps://doi.org/10.1016/j.jmb.2014.07.032openalex-snapshot
The Gene Silencing Transcription Factor REST Represses miR-132 Expression in Hippocampal Neurons Destined to Die
inferred← citeshttps://doi.org/10.1016/j.jmb.2016.10.004openalex-snapshot
Systematic Analysis of Known and Candidate Lysine Demethylases in the Regulation of Myoblast Differentiation
inferred← citeshttps://doi.org/10.1016/j.jmb.2023.168376openalex-snapshot
Distinct Histone H3 Lysine 27 Modifications Dictate Different Outcomes of Gene Transcription
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2010.12.003openalex-snapshot
Acetylation and nuclear receptor action
inferred← citeshttps://doi.org/10.1016/j.jtho.2019.06.021openalex-snapshot
Phase I, Open-Label, Dose-Escalation Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of GSK2879552 in Relapsed/Refractory SCLC
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