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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

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1 of the 44 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1172/jci23187 (notice 2016-11-01).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/0471143030.cb0303s04openalex-snapshot
Isolation of Mitochondria from Tissues and Cells by Differential Centrifugation
inferredcites →https://doi.org/10.1002/0471143030.cb0304s04openalex-snapshot
Purification of a Crude Mitochondrial Fraction by Density‐Gradient Centrifugation
inferredcites →https://doi.org/10.1002/hep.22284openalex-snapshot
Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl–CoA dehydrogenase (MCAD)–deficient mice
inferredcites →https://doi.org/10.1016/0006-2944(85)90124-3openalex-snapshot
Fluorometric assay of acyl-CoA dehydrogenases in normal and mutant human fibroblasts
inferredcites →https://doi.org/10.1016/0076-6879(69)13005-0openalex-snapshot
[1] Citrate synthase
inferredcites →https://doi.org/10.1016/b978-0-12-457950-7.x5001-3openalex-snapshot
A Flexible System of Enzymatic Analysis
inferredcites →https://doi.org/10.1016/j.bbrc.2003.12.120openalex-snapshot
Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo
inferredcites →https://doi.org/10.1016/j.cell.2007.07.035openalex-snapshot
Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival
inferredcites →https://doi.org/10.1016/j.cell.2007.11.025openalex-snapshot
Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer
inferredcites →https://doi.org/10.1016/j.cmet.2007.11.006openalex-snapshot
Conserved Metabolic Regulatory Functions of Sirtuins
inferredcites →https://doi.org/10.1016/j.lfs.2008.04.021openalex-snapshot
Adipose tissue gene expression profiles in ob/ob mice treated with leptin
inferredcites →https://doi.org/10.1016/j.molcel.2006.06.026openalex-snapshot
Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey
inferredcites →https://doi.org/10.1016/s0021-9258(18)64849-5openalex-snapshot
A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES
inferredcites →https://doi.org/10.1016/s0022-2275(20)40190-7openalex-snapshot
Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride–methanol
inferredcites →https://doi.org/10.1016/s0076-6879(09)05008-3openalex-snapshot
Chapter 8 Acetylation of Mitochondrial Proteins
inferredcites →https://doi.org/10.1016/s0091-679x(06)80009-9openalex-snapshot
Assays of Fatty Acid β‐Oxidation Activity
inferredcites →https://doi.org/10.1038/nature05486openalex-snapshot
Sirtuins as potential targets for metabolic syndrome
inferredcites →https://doi.org/10.1038/nbt1046openalex-snapshot
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells
inferredcites →https://doi.org/10.1042/bj3200345openalex-snapshot
Mammalian mitochondrial β -oxidation
inferredcites →https://doi.org/10.1055/s-2006-954581openalex-snapshot
Evidence for Impaired Gluconeogenesis in Very Long-chain Acyl-CoA Dehydrogenase-deficient Mice
inferredcites →https://doi.org/10.1073/pnas.0402511101openalex-snapshot
Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse
inferredcites →https://doi.org/10.1073/pnas.0407574101openalex-snapshot
Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: An in vivo analysis in MIRKO mice
inferredcites →https://doi.org/10.1073/pnas.0603968103openalex-snapshot
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
inferredcites →https://doi.org/10.1073/pnas.0604392103openalex-snapshot
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
inferredcites →https://doi.org/10.1073/pnas.0707060104openalex-snapshot
Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance
inferredcites →https://doi.org/10.1073/pnas.0803790105openalex-snapshot
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
inferredcites →https://doi.org/10.1073/pnas.83.10.3086openalex-snapshot
Hepatocellular influx of [14C]oleate reflects membrane transport rather than intracellular metabolism or binding.
inferredcites →https://doi.org/10.1073/pnas.95.26.15592openalex-snapshot
Targeted disruption of mouse long-chain acyl-CoA dehydrogenase gene reveals crucial roles for fatty acid oxidation
inferredcites →https://doi.org/10.1074/jbc.m604350200openalex-snapshot
Compensatory Responses to Pyruvate Carboxylase Suppression in Islet β-Cells
inferredcites →https://doi.org/10.1083/jcb.200205057openalex-snapshot
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase
inferredcites →https://doi.org/10.1093/hmg/10.19.2069openalex-snapshot
Gestational, pathologic and biochemical differences between very long-chain acyl-CoA dehydrogenase deficiency and long-chain acyl-CoA dehydrogenase deficiency in the mouse
inferredcites →https://doi.org/10.1093/ilar.43.2.57openalex-snapshot
Mouse Models for Disorders of Mitochondrial Fatty Acid -Oxidation
inferredcites →https://doi.org/10.1101/gr.3124505openalex-snapshot
Database of mRNA gene expression profiles of multiple human organs
inferredcites →https://doi.org/10.1111/j.1440-1746.2006.04698.xopenalex-snapshot
Significant correlations between severe fatty liver and risk factors for metabolic syndrome
inferredcites →https://doi.org/10.1111/j.1474-9726.2009.00503.xopenalex-snapshot
Calorie restriction alters mitochondrial protein acetylation
inferredcites →https://doi.org/10.1128/mcb.01636-07openalex-snapshot
Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation
inferredcites →https://doi.org/10.1139/o59-099openalex-snapshot
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION
inferredcites →https://doi.org/10.1146/annurev.bi.49.070180.002143openalex-snapshot
Regulation of Hepatic Fatty Acid Oxidation and Ketone Body Production
inferredcites →https://doi.org/10.1152/ajpendo.2000.279.5.e1039openalex-snapshot
Lipid oxidation is reduced in obese human skeletal muscle
inferredcites →https://doi.org/10.1172/jci19574openalex-snapshot
ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease
inferredcites →https://doi.org/10.1172/jci23187openalex-snapshot
Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
inferredcites →https://doi.org/10.1371/journal.pgen.0010023openalex-snapshot
Medium-Chain Acyl-CoA Dehydrogenase Deficiency in Gene-Targeted Mice
inferredcites →https://doi.org/10.2337/dc07-0792openalex-snapshot
Nonalcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-Aged Japanese Men
inferredcites →https://doi.org/10.2337/diabetes.54.12.3541openalex-snapshot
Nonalcoholic Fatty Liver Disease and Risk of Future Cardiovascular Events Among Type 2 Diabetic Patients

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3219265openalex-extracted
Targeting Hepatic Glutaminase 1 Ameliorates Non-Alcoholic Steatohepatitis by Restoring Disrupted Hepatic Very-Low Density Lipoproteins Triglyceride Assembly
inferred← citeshttps://doi.org/10.1002/1873-3468.13779openalex-snapshot
NAD+/sirtuin metabolism is enhanced in response to cold‐induced changes in lipid metabolism in mouse liver
inferred← citeshttps://doi.org/10.1002/1873-3468.14310openalex-snapshot
Diet‐derived ergothioneine induces necroptosis in colorectal cancer cells by activating the SIRT3/MLKL pathway
inferred← citeshttps://doi.org/10.1002/9781118387658.ch13openalex-snapshot
Regulation of glucose metabolism in liver
inferred← citeshttps://doi.org/10.1002/9781118663387.ch27openalex-snapshot
Sirtuins
inferred← citeshttps://doi.org/10.1002/9783527809257.ch12openalex-snapshot
Histone Acetyltransferases: Targets and Inhibitors
inferred← citeshttps://doi.org/10.1002/advs.202204190openalex-snapshot
PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms
inferred← citeshttps://doi.org/10.1002/advs.202206144openalex-snapshot
Reprogramming of Mitochondrial Respiratory Chain Complex by Targeting SIRT3‐COX4I2 Axis Attenuates Osteoarthritis Progression
inferred← citeshttps://doi.org/10.1002/advs.202307256openalex-snapshot
Role of Argininosuccinate Synthase 1 ‐Dependent L‐Arginine Biosynthesis in the Protective Effect of Endothelial Sirtuin 3 Against Atherosclerosis
inferred← citeshttps://doi.org/10.1002/advs.202411235openalex-snapshot
SIRT3‐Mediated Deacetylation of DRP1 K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease
inferred← citeshttps://doi.org/10.1002/ange.202218312openalex-snapshot
ATP‐Independent and Cell‐Free Biosynthesis of β‐Hydroxy Acids Using Vinyl Esters as Smart Substrates
inferred← citeshttps://doi.org/10.1002/ange.202412296openalex-snapshot
Ligand‐Enabled Pd‐Catalyzed sp3 C−H Macrocyclization: Synthesis and Evaluation of Macrocyclic Sulfonamide for the Treatment of Parkinson's Disease
inferred← citeshttps://doi.org/10.1002/anie.202218312openalex-snapshot
ATP‐Independent and Cell‐Free Biosynthesis of β‐Hydroxy Acids Using Vinyl Esters as Smart Substrates
inferred← citeshttps://doi.org/10.1002/anie.202412296openalex-snapshot
Ligand‐Enabled Pd‐Catalyzed sp 3 C−H Macrocyclization: Synthesis and Evaluation of Macrocyclic Sulfonamide for the Treatment of Parkinson's Disease
inferred← citeshttps://doi.org/10.1002/bies.202100014openalex-snapshot
NIPSNAP protein family emerges as a sensor of mitochondrial health
inferred← citeshttps://doi.org/10.1002/biof.112openalex-snapshot
Therapeutic potential of activators and inhibitors of sirtuins
inferred← citeshttps://doi.org/10.1002/biof.2116openalex-snapshot
Comparative effects of viable Lactobacillus rhamnosus GG and its heat‐inactivated paraprobiotic in the prevention of high‐fat high‐fructose diet‐induced non‐alcoholic fatty liver disease in rats
inferred← citeshttps://doi.org/10.1002/cam4.70786openalex-snapshot
Role of SIRT7 in Prostate Cancer Progression: New Insight Into Potential Therapeutic Target
inferred← citeshttps://doi.org/10.1002/cbf.3763openalex-snapshot
Epigenetics and mitochondrial dysfunction insights into the impact of the progression of non‐alcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1002/cbic.201000292openalex-snapshot
Lysine Acetylation: The Tale of a Modification from Transcription Regulation to Metabolism
inferred← citeshttps://doi.org/10.1002/cbic.201500364openalex-snapshot
The ɛ‐Amino Group of Protein Lysine Residues Is Highly Susceptible to Nonenzymatic Acylation by Several Physiological Acyl‐CoA Thioesters
inferred← citeshttps://doi.org/10.1002/chem.201905338openalex-snapshot
Photo Cross‐Linking Probes Containing ϵ‐ N ‐Thioacyllysine and ϵ‐ N ‐Acyl‐(δ‐aza)lysine Residues
inferred← citeshttps://doi.org/10.1002/cmdc.201300421openalex-snapshot
An Update on Lysine Deacylases Targeting the Expanding “Acylome”
inferred← citeshttps://doi.org/10.1002/cns.71139openalex-snapshot
P7C3 Compounds as Targeted Mitochondrial Therapeutics for Brain Disorders
inferred← citeshttps://doi.org/10.1002/cphy.c130024openalex-snapshot
Energy Metabolism in the Liver
inferred← citeshttps://doi.org/10.1002/cphy.c140064openalex-snapshot
Metabolic Flexibility: Hibernation, Torpor, and Estivation
inferred← citeshttps://doi.org/10.1002/cphy.c170001openalex-snapshot
Brown and Beige Adipose Tissues in Health and Disease
inferred← citeshttps://doi.org/10.1002/cphy.c200013openalex-snapshot
Glucagon's Metabolic Action in Health and Disease
inferred← citeshttps://doi.org/10.1002/ctm2.852openalex-snapshot
Mitochondrial GCN5L1 regulates glutaminase acetylation and hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1002/dmrr.70201openalex-snapshot
The Sirtuin Network: Linking NAD + Metabolism, Mitochondrial Function, and Metabolic Homoeostasis
inferred← citeshttps://doi.org/10.1002/ehf2.13198openalex-snapshot
Doxorubicin-Induced and Trastuzumab-Induced Cardiotoxicity in Mice is Not Prevented by Metoprolol
inferred← citeshttps://doi.org/10.1002/ehf2.13274openalex-snapshot
Metabolomics and Cardiovascular Imaging: A Combined Approach for Cardiovascular Ageing
inferred← citeshttps://doi.org/10.1002/emmm.201303782openalex-snapshot
Mitochondrial response to nutrient availability and its role in metabolic disease
inferred← citeshttps://doi.org/10.1002/hep.26085openalex-snapshot
HINT2 and fatty liver disease: Mitochondrial protein hyperacetylation gives a hint?
inferred← citeshttps://doi.org/10.1002/hep.28707openalex-snapshot
G‐protein‐coupled bile acid receptor plays a key role in bile acid metabolism and fasting‐induced hepatic steatosis in mice
inferred← citeshttps://doi.org/10.1002/hep.29229openalex-snapshot
Sirtuin 3 acts as a negative regulator of autophagy dictating hepatocyte susceptibility to lipotoxicity
inferred← citeshttps://doi.org/10.1002/hep.30876openalex-snapshot
Mitochondrial General Control of Amino Acid Synthesis 5 Like 1 Regulates Glutaminolysis, Mammalian Target of Rapamycin Complex 1 Activity, and Murine Liver Regeneration
inferred← citeshttps://doi.org/10.1002/hep.31409openalex-snapshot
Acyl‐Coenzyme A Thioesterase 9 Traffics Mitochondrial Short‐Chain Fatty Acids Toward De Novo Lipogenesis and Glucose Production in the Liver
inferred← citeshttps://doi.org/10.1002/hsr2.1145openalex-snapshot
Curcumin effects on chronic obstructive pulmonary disease: A systematic review
inferred← citeshttps://doi.org/10.1002/iid3.70106openalex-snapshot
Blast‐Overpressure Induced Modulation of PARP‐SIRT‐NRF2 Axis in Stress Signaling of Astrocytes and Microglia
inferred← citeshttps://doi.org/10.1002/inmd.70159openalex-snapshot
Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells
inferred← citeshttps://doi.org/10.1002/iub.1246openalex-snapshot
The sirtuin class of histone deacetylases: Regulation and roles in lipid metabolism
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2014.tb00548.xopenalex-snapshot
Energy Metabolism in the Liver
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2016.tb00689.xopenalex-snapshot
Metabolic Flexibility: Hibernation, Torpor, and Estivation
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2017.tb00784.xopenalex-snapshot
Brown and Beige Adipose Tissues in Health and Disease
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2021.tb00161.xopenalex-snapshot
Glucagon's Metabolic Action in Health and Disease
inferred← citeshttps://doi.org/10.1002/jbmr.4721openalex-snapshot
Sirt3 Promotes Chondrogenesis, Chondrocyte Mitochondrial Respiration and the Development of High-Fat Diet-Induced Osteoarthritis in Mice
inferred← citeshttps://doi.org/10.1002/jbt.23047openalex-snapshot
Versatile role of sirtuins in metabolic disorders: From modulation of mitochondrial function to therapeutic interventions
inferred← citeshttps://doi.org/10.1002/jbt.23422openalex-snapshot
Melatonin attenuates monocrotaline‐induced hepatic sinusoidal obstruction syndrome in rats via activation of Sirtuin‐3
inferred← citeshttps://doi.org/10.1002/jbt.23812openalex-snapshot
The influential responsibility of sirtuins in senescence and associated diseases: A review
inferred← citeshttps://doi.org/10.1002/jcb.22795openalex-snapshot
Characterization of murine SIRT3 transcript variants and corresponding protein products
inferred← citeshttps://doi.org/10.1002/jcb.30197openalex-snapshot
Protein acetylation effects on enzyme activity and metabolic pathway fluxes
inferred← citeshttps://doi.org/10.1002/jcp.27200openalex-snapshot
Emerging role of SIRT3 in endothelial metabolism, angiogenesis, and cardiovascular disease
inferred← citeshttps://doi.org/10.1002/jcp.31328openalex-snapshot
The role of sirtuins in intervertebral disc degeneration: Mechanisms and therapeutic potential
inferred← citeshttps://doi.org/10.1002/jcsm.12322openalex-snapshot
Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure
inferred← citeshttps://doi.org/10.1002/jdn.10313openalex-snapshot
Late pregnancy maternal naringin supplementation affects the mitochondria in the cerebellum of Wistar rat offspring via sirtuin 3 and AKT
inferred← citeshttps://doi.org/10.1002/jgm.70007openalex-snapshot
Revealing the Complex Interaction of Noncoding RNAs, Sirtuin Family, and Mitochondrial Function
inferred← citeshttps://doi.org/10.1002/jimd.12296openalex-snapshot
Increased protein propionylation contributes to mitochondrial dysfunction in liver cells and fibroblasts, but not in myotubes
inferred← citeshttps://doi.org/10.1002/jimd.12617openalex-snapshot
New insights into the pathophysiology of methylmalonic acidemia
inferred← citeshttps://doi.org/10.1002/jmd2.12218openalex-snapshot
SLC25A42 ‐associated mitochondrial encephalomyopathy: Report of additional founder cases and functional characterization of a novel deletion
inferred← citeshttps://doi.org/10.1002/jnr.23806openalex-snapshot
Sirtuins as modifiers of Parkinson's disease pathology
inferred← citeshttps://doi.org/10.1002/jso.24043openalex-snapshot
Loss of ACSS2 expression predicts poor prognosis in patients with gastric cancer
inferred← citeshttps://doi.org/10.1002/mas.21618openalex-snapshot
MASS SPECTROMETRY‐BASED MITOCHONDRIAL PROTEOMICS IN HUMAN OVARIAN CANCERS
inferred← citeshttps://doi.org/10.1002/mco2.70127openalex-snapshot
Colorectal Cancer: Pathogenesis and Targeted Therapy
inferred← citeshttps://doi.org/10.1002/mco2.70866openalex-snapshot
SIRT Family: Biological Functions and Therapeutic Targets
inferred← citeshttps://doi.org/10.1002/med.21436openalex-snapshot
The Current State of NAD+‐Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets
inferred← citeshttps://doi.org/10.1002/med.22076openalex-snapshot
Activation and inhibition of sirtuins: From bench to bedside
inferred← citeshttps://doi.org/10.1002/mnfr.201100509openalex-snapshot
Molecular mechanisms for anti‐aging by natural dietary compounds
inferred← citeshttps://doi.org/10.1002/mnfr.201700828openalex-snapshot
Oral Administration of Edible Seaweed Undaria Pinnatifida (Wakame) Modifies Glucose and Lipid Metabolism in Rats: A DNA Microarray Analysis
inferred← citeshttps://doi.org/10.1002/mnfr.201900043openalex-snapshot
Mitochondria‐Mediated Pathogenesis and Therapeutics for Non‐Alcoholic Fatty Liver Disease
inferred← citeshttps://doi.org/10.1002/mnfr.202200225openalex-snapshot
Polyphenols in Highland Barley Tea Inhibit the Production of Advanced Glycosylation End‐Products and Alleviate the Skeletal Muscle Damage
inferred← citeshttps://doi.org/10.1002/oby.22065openalex-snapshot
Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting
inferred← citeshttps://doi.org/10.1002/pmic.201300376openalex-snapshot
Mitochondria in metabolic disease: Getting clues from proteomic studies
inferred← citeshttps://doi.org/10.1002/prot.70082openalex-snapshot
Human Citrate Synthase Post‐Translational Modification Mimics and Molecular Dynamic Simulations Demonstrate Attenuation of Acetyl‐ CoA / CoA Binding
inferred← citeshttps://doi.org/10.1002/ptr.7965openalex-snapshot
Fatty acid metabolism disorders and potential therapeutic traditional Chinese medicines in cardiovascular diseases
inferred← citeshttps://doi.org/10.1002/sstr.202400014openalex-snapshot
Photothermal Microneedle Hydrogel Patch for Refractory Soft Tissue Injuries through Thermosensitized Anti‐Inflammaging Modulation
inferred← citeshttps://doi.org/10.1002/tox.24412openalex-snapshot
Resveratrol Alleviated T‐2 Toxin‐Induced Liver Injury via Preservation of Nrf2 Pathway and GSH Synthesis
inferred← citeshttps://doi.org/10.1002/tox.24582openalex-snapshot
Acute Inhalation Exposure to Ultrafine Carbon Black Alters Mitochondrial Substrate Utilization in the Heart
inferred← citeshttps://doi.org/10.1002/wsbm.1373openalex-snapshot
Traditional and novel tools to probe the mitochondrial metabolism in health and disease
inferred← citeshttps://doi.org/10.1007/164_2015_5openalex-snapshot
Nuclear Receptor Coregulators in Metabolism and Disease
inferred← citeshttps://doi.org/10.1007/978-1-0716-1712-0_5openalex-snapshot
Role of SIRT3 and Mitochondrial Dysfunction in Neurodegeneration
inferred← citeshttps://doi.org/10.1007/978-1-4614-5203-4_19openalex-snapshot
Role of Sirtuins in Regulation of Cardiac Adaptation Associated with Hypertrophy
inferred← citeshttps://doi.org/10.1007/978-1-4939-1203-2_4openalex-snapshot
Critical Importance of the Perinatal Period in the Development of Obesity
inferred← citeshttps://doi.org/10.1007/978-1-4939-1227-8_5openalex-snapshot
Cardiac Energy Metabolism in Heart Failure Associated with Obesity and Diabetes
inferred← citeshttps://doi.org/10.1007/978-1-4939-1227-8_8openalex-snapshot
Acetylation in the Control of Mitochondrial Metabolism and Integrity
inferred← citeshttps://doi.org/10.1007/978-1-4939-3667-0_14openalex-snapshot
Cloning and Characterization of Sirtuin3 (SIRT3)
inferred← citeshttps://doi.org/10.1007/978-1-4939-6386-7_12openalex-snapshot
Developmental Programming of Nonalcoholic Fatty Liver Disease (NAFLD)
inferred← citeshttps://doi.org/10.1007/978-1-4939-9802-9_7openalex-snapshot
Proteomic Profiling of Human Skeletal Muscle in Health and Disease
inferred← citeshttps://doi.org/10.1007/978-1-62703-101-1_6openalex-snapshot
The Role of Mitochondrial DNA in Tumorigenesis
inferred← citeshttps://doi.org/10.1007/978-1-62703-637-5_1openalex-snapshot
Introduction: Sirtuins in Aging and Diseases
inferred← citeshttps://doi.org/10.1007/978-1-62703-637-5_16openalex-snapshot
Oxygen Flux Analysis to Understand the Biological Function of Sirtuins
inferred← citeshttps://doi.org/10.1007/978-3-030-12668-1_3openalex-snapshot
Current Models of Fatty Liver Disease; New Insights, Therapeutic Targets and Interventions
inferred← citeshttps://doi.org/10.1007/978-3-030-56905-1_2openalex-snapshot
Sirtuin Deacetylases: Linking Mycobacterial Infection and Host Metabolism
inferred← citeshttps://doi.org/10.1007/978-3-031-07634-3_12openalex-snapshot
Metabolic Regulation of Lysine Acetylation: Implications in Cancer
inferred← citeshttps://doi.org/10.1007/978-3-031-07634-3_8openalex-snapshot
Nutritional Epigenetics: How Metabolism Epigenetically Controls Cellular Physiology, Gene Expression and Disease
inferred← citeshttps://doi.org/10.1007/978-3-031-47065-3_8openalex-snapshot
The Effects of Exercise on Skeletal Muscle
inferred← citeshttps://doi.org/10.1007/978-3-031-88361-3_17openalex-snapshot
Protein Acetylation and NAD+ Homeostasis in Aging Muscle
inferred← citeshttps://doi.org/10.1007/978-3-031-91459-1_9openalex-snapshot
Acetylation in Cardiac Aging: Molecular Mechanism and Therapeutic Approaches
inferred← citeshttps://doi.org/10.1007/978-3-031-93459-9_21openalex-snapshot
Protective Effects of Coffee on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Potential Interplay with the Gut Microbiome
inferred← citeshttps://doi.org/10.1007/978-3-032-08045-5_8openalex-snapshot
Exercise-Induced Epigenetics Modulation of Metabolism
inferred← citeshttps://doi.org/10.1007/978-3-642-21631-2_8openalex-snapshot
Mitochondrial Sirtuins in the Regulation of Mitochondrial Activity and Metabolic Adaptation
inferred← citeshttps://doi.org/10.1007/978-3-642-25950-0_6openalex-snapshot
Circadian Clocks and Metabolism
inferred← citeshttps://doi.org/10.1007/978-3-7091-1883-2_14openalex-snapshot
Post-translational Modification
inferred← citeshttps://doi.org/10.1007/978-94-024-0962-8_1openalex-snapshot
Biochemistry and Enzymology of Sirtuins
inferred← citeshttps://doi.org/10.1007/978-94-024-0962-8_12openalex-snapshot
Sirtuin Activation by Small Molecules
inferred← citeshttps://doi.org/10.1007/978-94-024-0962-8_3openalex-snapshot
Protein Lysine Acylation: Abundance, Dynamics and Function
inferred← citeshttps://doi.org/10.1007/978-94-024-0962-8_5openalex-snapshot
Deacetylation by SIRT3 Relieves Inhibition of Mitochondrial Protein Function
inferred← citeshttps://doi.org/10.1007/978-94-024-0962-8_9openalex-snapshot
Sirtuins as Metabolic Modulators of Muscle Plasticity
inferred← citeshttps://doi.org/10.1007/978-981-13-8367-0_4openalex-snapshot
Mitochondria Lysine Acetylation and Phenotypic Control
inferred← citeshttps://doi.org/10.1007/978-981-15-2509-4_1openalex-snapshot
Introduction to Protein Posttranslational Modifications (PTMs)
inferred← citeshttps://doi.org/10.1007/978-981-15-4501-6_111-1openalex-snapshot
Noncoding RNAs Regulation of Redox Balance in Cancer
inferred← citeshttps://doi.org/10.1007/978-981-15-9411-3_111openalex-snapshot
Noncoding RNAs Regulation of Redox Balance in Cancer
inferred← citeshttps://doi.org/10.1007/s00011-026-02353-zopenalex-snapshot
BGP-15 ameliorates sepsis-induced cardiomyopathy via SIRT3/SOD2-associated antioxidant signaling and suppression of myocardial inflammation
inferred← citeshttps://doi.org/10.1007/s00018-010-0402-yopenalex-snapshot
Protein deacetylation by sirtuins: delineating a post-translational regulatory program responsive to nutrient and redox stressors
inferred← citeshttps://doi.org/10.1007/s00018-014-1574-7openalex-snapshot
Circadian clocks and energy metabolism
inferred← citeshttps://doi.org/10.1007/s00018-016-2180-7openalex-snapshot
Using mitochondrial sirtuins as drug targets: disease implications and available compounds
inferred← citeshttps://doi.org/10.1007/s00018-016-2280-4openalex-snapshot
Post-translational modifications in mitochondria: protein signaling in the powerhouse
inferred← citeshttps://doi.org/10.1007/s00018-016-2431-7openalex-snapshot
The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome
inferred← citeshttps://doi.org/10.1007/s00018-023-04771-2openalex-snapshot
Effects of short-term endurance and strength exercise in the molecular regulation of skeletal muscle in hyperinsulinemic and hyperglycemic Slc2a4+/− mice
inferred← citeshttps://doi.org/10.1007/s00018-023-05064-4openalex-snapshot
Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models
inferred← citeshttps://doi.org/10.1007/s00109-017-1616-3openalex-snapshot
Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice
inferred← citeshttps://doi.org/10.1007/s00125-011-2304-4openalex-snapshot
Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice
inferred← citeshttps://doi.org/10.1007/s00125-013-2851-yopenalex-snapshot
Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients
inferred← citeshttps://doi.org/10.1007/s00232-012-9426-6openalex-snapshot
Unsaturation of Mitochondrial Membrane Lipids is Related to Palmitate Oxidation in Subsarcolemmal and Intermyofibrillar Mitochondria
inferred← citeshttps://doi.org/10.1007/s00246-018-1848-1openalex-snapshot
Sirtuins in the Cardiovascular System: Potential Targets in Pediatric Cardiology
inferred← citeshttps://doi.org/10.1007/s00268-013-2359-0openalex-snapshot
SIRT3 Expression as a Biomarker for Better Prognosis in Gastric Cancer
inferred← citeshttps://doi.org/10.1007/s00335-014-9533-zopenalex-snapshot
Approach to assessing determinants of glucose homeostasis in the conscious mouse
inferred← citeshttps://doi.org/10.1007/s00335-016-9651-xopenalex-snapshot
Mitophagy plays a central role in mitochondrial ageing
inferred← citeshttps://doi.org/10.1007/s00395-012-0273-5openalex-snapshot
Emerging beneficial roles of sirtuins in heart failure
inferred← citeshttps://doi.org/10.1007/s00395-013-0399-0openalex-snapshot
Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development
inferred← citeshttps://doi.org/10.1007/s00395-015-0493-6openalex-snapshot
SIRT3 deficiency impairs mitochondrial and contractile function in the heart
inferred← citeshttps://doi.org/10.1007/s00395-023-01013-1openalex-snapshot
Outcomes of hypothalamic oxytocin neuron-driven cardioprotection after acute myocardial infarction
inferred← citeshttps://doi.org/10.1007/s00415-013-6970-7openalex-snapshot
Genetic association of sirtuin genes and Parkinson’s disease
inferred← citeshttps://doi.org/10.1007/s00421-015-3232-7openalex-snapshot
Effect of regional muscle location but not adiposity on mitochondrial biogenesis-regulating proteins
inferred← citeshttps://doi.org/10.1007/s00424-018-2164-6openalex-snapshot
Training state and fasting-induced PDH regulation in human skeletal muscle
inferred← citeshttps://doi.org/10.1007/s00424-020-02359-4openalex-snapshot
Fiber-specific and whole-muscle LRP130 expression in rested, exercised, and fasted human skeletal muscle
inferred← citeshttps://doi.org/10.1007/s00467-020-04866-zopenalex-snapshot
Sirtuins play critical and diverse roles in acute kidney injury
inferred← citeshttps://doi.org/10.1007/s00535-013-0791-4openalex-snapshot
Mitochondrial metabolism in the noncancerous liver determine the occurrence of hepatocellular carcinoma: a prospective study
inferred← citeshttps://doi.org/10.1007/s00726-015-2126-7openalex-snapshot
β-Hydroxy-β-methylbutyrate, mitochondrial biogenesis, and skeletal muscle health
inferred← citeshttps://doi.org/10.1007/s00726-019-02765-8openalex-snapshot
Establishment of reference values for the lysine acetylation marker Nɛ-acetyllysine in small volume human plasma samples by a multi-target LC–MS/MS method
inferred← citeshttps://doi.org/10.1007/s10059-013-0130-xopenalex-snapshot
Do Sirtuins Promote Mammalian Longevity?: A Critical Review on Its Relevance to the Longevity Effect Induced by Calorie Restriction
inferred← citeshttps://doi.org/10.1007/s10495-024-02003-xopenalex-snapshot
Glutamine deprivation in glioblastoma stem cells triggers autophagic SIRT3 degradation to epigenetically restrict CD133 expression and stemness
inferred← citeshttps://doi.org/10.1007/s10522-017-9685-9openalex-snapshot
Sirtuins, a promising target in slowing down the ageing process
inferred← citeshttps://doi.org/10.1007/s10522-020-09868-wopenalex-snapshot
17β-estradiol inhibits H2O2-induced senescence in HUVEC cells through upregulating SIRT3 expression and promoting autophagy
inferred← citeshttps://doi.org/10.1007/s10522-022-09965-yopenalex-snapshot
Aging and short-term calorie restriction differently affect the cardiac and skeletal muscle expression of genes regulating energy substrate utilization in male rats
inferred← citeshttps://doi.org/10.1007/s10522-026-10445-wopenalex-snapshot
Stress is inevitable; recovery is conditional: bioenergetic limits of resilience in aging and disease
inferred← citeshttps://doi.org/10.1007/s10528-018-9868-3openalex-snapshot
Detection of Insertions/Deletions Within SIRT1, SIRT2 and SIRT3 Genes and Their Associations with Body Measurement Traits in Cattle
inferred← citeshttps://doi.org/10.1007/s10545-012-9480-3openalex-snapshot
Mitochondrial proteomics—a tool for the study of metabolic disorders
inferred← citeshttps://doi.org/10.1007/s10545-014-9684-9openalex-snapshot
Aberrant protein acylation is a common observation in inborn errors of acyl‐CoA metabolism
inferred← citeshttps://doi.org/10.1007/s10545-016-9939-8openalex-snapshot
Sirtuin activation as a therapeutic approach against inborn errors of metabolism
inferred← citeshttps://doi.org/10.1007/s10557-026-07843-0openalex-snapshot
Targeting SIRT3 in Diabetic Cardiomyopathy: Mechanism-Based Therapeutic Strategies
inferred← citeshttps://doi.org/10.1007/s10565-026-10138-7openalex-snapshot
SIRT3 attenuates AGEs-induced senescence in human granulosa cells through enhancing mitophagy
inferred← citeshttps://doi.org/10.1007/s10571-016-0452-2openalex-snapshot
Could Sirtuin Activities Modify ALS Onset and Progression?
inferred← citeshttps://doi.org/10.1007/s10620-017-4615-xopenalex-snapshot
Interplay Between SIRT-3, Metabolism and Its Tumor Suppressor Role in Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.1007/s10653-025-02547-0openalex-snapshot
Untargeted metabolomics offers insights into the risks of chronic exposure to mixtures of polycyclic aromatic hydrocarbons at environmentally relevant low concentrations
inferred← citeshttps://doi.org/10.1007/s10719-026-10223-3openalex-snapshot
Mechanistic and functional integration of sirtuin deacylases: from substrate specificity to biological outcomes
inferred← citeshttps://doi.org/10.1007/s10735-026-10935-8openalex-snapshot
Subcellular sirtuin signaling networks: pivotal regulators of cardiovascular homeostasis and remodeling
inferred← citeshttps://doi.org/10.1007/s10741-016-9570-7openalex-snapshot
Mitochondrial sirtuins in the heart
inferred← citeshttps://doi.org/10.1007/s10863-018-9752-1openalex-snapshot
Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition
inferred← citeshttps://doi.org/10.1007/s11010-016-2881-0openalex-snapshot
Post-translational modification by acetylation regulates the mitochondrial carnitine/acylcarnitine transport protein
inferred← citeshttps://doi.org/10.1007/s11010-017-2993-1openalex-snapshot
Methylene blue decreases mitochondrial lysine acetylation in the diabetic heart
inferred← citeshttps://doi.org/10.1007/s11010-019-03644-2openalex-snapshot
SIRT3 promotes the invasion and metastasis of cervical cancer cells by regulating fatty acid synthase
inferred← citeshttps://doi.org/10.1007/s11011-021-00895-1openalex-snapshot
LncRNA NEAT1 ameliorate ischemic stroke via promoting Mfn2 expression through binding to Nova and activates Sirt3
inferred← citeshttps://doi.org/10.1007/s11011-022-00956-zopenalex-snapshot
Crosstalk between Sirtuins and Nrf2: SIRT1 activators as emerging treatment for diabetic neuropathy
inferred← citeshttps://doi.org/10.1007/s11011-022-01111-4openalex-snapshot
Role of SIRT3 in neurological diseases and rehabilitation training
inferred← citeshttps://doi.org/10.1007/s11033-011-1096-4openalex-snapshot
Modulatory effect of resveratrol on SIRT1, SIRT3, SIRT4, PGC1α and NAMPT gene expression profiles in wild-type adult zebrafish liver
inferred← citeshttps://doi.org/10.1007/s11033-026-12062-9openalex-snapshot
MicroRNA–SIRT1 crosstalk in liver diseases: molecular regulation of metabolism, inflammation, and cell survival
inferred← citeshttps://doi.org/10.1007/s11055-023-01379-8openalex-snapshot
Sirtuins and Aging
inferred← citeshttps://doi.org/10.1007/s11064-014-1507-8openalex-snapshot
SIRT3 Attenuates MPTP-Induced Nigrostriatal Degeneration Via Enhancing Mitochondrial Antioxidant Capacity
inferred← citeshttps://doi.org/10.1007/s11064-016-2110-yopenalex-snapshot
Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders
inferred← citeshttps://doi.org/10.1007/s11239-018-1677-3openalex-snapshot
The effect of oxygen in Sirt3-mediated myocardial protection: a proof-of-concept study in cultured cardiomyoblasts
inferred← citeshttps://doi.org/10.1007/s11306-011-0370-8openalex-snapshot
Comparison of tissue harvest protocols for the quantitation of acylcarnitines in mouse heart and liver by mass spectrometry
inferred← citeshttps://doi.org/10.1007/s11306-016-1091-9openalex-snapshot
Transient decrease of hepatic NAD+ and amino acid alterations during treatment with valproate: new insights on drug-induced effects in vivo using targeted MS-based metabolomics
inferred← citeshttps://doi.org/10.1007/s11356-023-31683-2openalex-snapshot
Arsenic and adipose tissue: an unexplored pathway for toxicity and metabolic dysfunction
inferred← citeshttps://doi.org/10.1007/s11357-025-01847-8openalex-snapshot
Sirtuins mediate the reduction of age-related oxidative damage in the cochlea under a cocoa-rich diet
inferred← citeshttps://doi.org/10.1007/s11427-014-4709-zopenalex-snapshot
Mechanistic perspectives of calorie restriction on vascular homeostasis
inferred← citeshttps://doi.org/10.1007/s11427-024-2823-2openalex-snapshot
SIRT3 deficiency reduces PFKFB3-driven T-cell glycolysis and promotes arthritic inflammation
inferred← citeshttps://doi.org/10.1007/s11434-010-4038-yopenalex-snapshot
Novel findings in intermediary metabolism regulation
inferred← citeshttps://doi.org/10.1007/s11515-010-0700-7openalex-snapshot
Therapeutic potential and challenges of targeting sirtuins in neurodegenerative diseases
inferred← citeshttps://doi.org/10.1007/s11515-011-1126-6openalex-snapshot
Metabolism is regulated by protein acetylation
inferred← citeshttps://doi.org/10.1007/s11596-019-1997-3openalex-snapshot
Berberine Ameliorates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats via Activation of SIRT3/AMPK/ACC Pathway
inferred← citeshttps://doi.org/10.1007/s11897-022-00550-5openalex-snapshot
Harnessing NAD+ Metabolism as Therapy for Cardiometabolic Diseases
inferred← citeshttps://doi.org/10.1007/s12012-020-09626-xopenalex-snapshot
Mitochondrial Sirtuins and Doxorubicin-induced Cardiotoxicity
inferred← citeshttps://doi.org/10.1007/s12012-025-10052-0openalex-snapshot
Sirtuins as Endogenous Regulators of Cardiac Fibrosis: A Current Perspective
inferred← citeshttps://doi.org/10.1007/s12020-018-1689-yopenalex-snapshot
Berberine promotes glucose uptake and inhibits gluconeogenesis by inhibiting deacetylase SIRT3
inferred← citeshttps://doi.org/10.1007/s12035-018-1399-8openalex-snapshot
Sirtuin3 Protected Against Neuronal Damage and Cycled into Nucleus in Status Epilepticus Model
inferred← citeshttps://doi.org/10.1007/s12264-023-01060-7openalex-snapshot
nNOS and Neurological, Neuropsychiatric Disorders: A 20-Year Story
inferred← citeshttps://doi.org/10.1007/s12265-020-09984-5openalex-snapshot
Exendin-4 Protects Against Myocardial Ischemia-Reperfusion Injury by Upregulation of SIRT1 and SIRT3 and Activation of AMPK
inferred← citeshttps://doi.org/10.1007/s12975-017-0544-4openalex-snapshot
Emerging Roles of Sirtuins in Ischemic Stroke
inferred← citeshttps://doi.org/10.1007/s13105-019-00711-6openalex-snapshot
GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes
inferred← citeshttps://doi.org/10.1007/s13148-010-0004-4openalex-snapshot
Continuous multiparametric monitoring of cell metabolism in response to transient overexpression of the sirtuin deacetylase SIRT3
inferred← citeshttps://doi.org/10.1007/s13148-010-0008-0openalex-snapshot
The sirtuins in the pathogenesis of cancer
inferred← citeshttps://doi.org/10.1007/s13238-021-00846-7openalex-snapshot
Metabolic reprogramming and epigenetic modifications on the path to cancer
inferred← citeshttps://doi.org/10.1007/s13277-015-4522-8openalex-snapshot
The expression levels of the sirtuins in patients with BCC
inferred← citeshttps://doi.org/10.1007/s13311-013-0214-5openalex-snapshot
Sirtuin Deacetylases as Therapeutic Targets in the Nervous System
inferred← citeshttps://doi.org/10.1007/s13340-015-0226-yopenalex-snapshot
Role of SIRT7 in hepatic lipid metabolism
inferred← citeshttps://doi.org/10.1007/s13361-016-1476-zopenalex-snapshot
Quantification of Lysine Acetylation and Succinylation Stoichiometry in Proteins Using Mass Spectrometric Data-Independent Acquisitions (SWATH)
inferred← citeshttps://doi.org/10.1007/s13679-025-00609-zopenalex-snapshot
Time Restricted Eating: A Valuable Alternative to Calorie Restriction for Addressing Obesity?
inferred← citeshttps://doi.org/10.1007/s40139-013-0021-zopenalex-snapshot
Role of Mitochondria in Alcoholic Liver Disease
inferred← citeshttps://doi.org/10.1007/s40142-017-0125-6openalex-snapshot
Advances in the Understanding and Treatment of Mitochondrial Fatty Acid Oxidation Disorders
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