On the public citation graph
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
0 signed · 1502 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.ccr.2009.12.040openalex-snapshot
A Higher-Order Complex Containing AF4 and ENL Family Proteins with P-TEFb Facilitates Oncogenic and Physiologic MLL-Dependent Transcription
inferredcites →https://doi.org/10.1016/j.ccr.2010.04.012openalex-snapshot
The PAF Complex Synergizes with MLL Fusion Proteins at HOX Loci to Promote Leukemogenesis
inferredcites →https://doi.org/10.1016/j.molcel.2005.06.027openalex-snapshot
The Bromodomain Protein Brd4 Is a Positive Regulatory Component of P-TEFb and Stimulates RNA Polymerase II-Dependent Transcription
inferredcites →https://doi.org/10.1016/j.molcel.2005.06.029openalex-snapshot
Recruitment of P-TEFb for Stimulation of Transcriptional Elongation by the Bromodomain Protein Brd4
inferredcites →https://doi.org/10.1016/j.molcel.2010.01.026openalex-snapshot
AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia
inferredcites →https://doi.org/10.1016/j.molcel.2010.05.011openalex-snapshot
Multiple Interactions Recruit MLL1 and MLL1 Fusion Proteins to the HOXA9 Locus in Leukemogenesis
inferredcites →https://doi.org/10.1016/j.stem.2008.11.015openalex-snapshot
Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells
inferredcites →https://doi.org/10.1021/jm200108topenalex-snapshot
Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains
inferredcites →https://doi.org/10.1038/nature08448openalex-snapshot
JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin
inferredcites →https://doi.org/10.1038/nature09504openalex-snapshot
Selective inhibition of BET bromodomains
inferredcites →https://doi.org/10.1038/nature09589openalex-snapshot
Suppression of inflammation by a synthetic histone mimic
inferredcites →https://doi.org/10.1038/nature10334openalex-snapshot
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
inferredcites →https://doi.org/10.1038/nbt.1759openalex-snapshot
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
inferredcites →https://doi.org/10.1038/nm.2305openalex-snapshot
Cancer epigenetics reaches mainstream oncology
inferredcites →https://doi.org/10.1038/nrc2253openalex-snapshot
MLL translocations, histone modifications and leukaemia stem-cell development
inferredcites →https://doi.org/10.1038/sj.emboj.7600521openalex-snapshot
Conditional MLL‐CBP targets GMP and models therapy‐related myeloproliferative disease
inferredcites →https://doi.org/10.1111/j.1365-2141.2008.07100.xopenalex-snapshot
Abundant anti‐apoptotic BCL‐2 is a molecular target in leukaemias with t(4;11) translocation
inferredcites →https://doi.org/10.1128/mcb.22.18.6509-6520.2002openalex-snapshot
A Mammalian Bromodomain Protein, Brd4, Interacts with Replication Factor C and Inhibits Progression to S Phase
inferredcites →https://doi.org/10.1182/blood-2002-07-2307openalex-snapshot
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
inferredcites →https://doi.org/10.1182/blood-2010-07-298349openalex-snapshot
The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells
inferredcites →https://doi.org/10.1182/blood-2010-12-324699openalex-snapshot
MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4765186openalex-extracted
The Epigenetic Roles of Bet Inhibitors Jq1 and I-Bet726 in Regulating Inflammation and Treatment for Experimental Autoimmune Encephalomyelitis
inferred← citeshttps://doi.org/10.1002/9781118681121.ch20openalex-snapshot
Targeting Protein–Protein Interactions Perspective
inferred← citeshttps://doi.org/10.1002/9781119000822.hfcm006.pub2openalex-snapshot
Epigenetic Contributions to Human Cancer
inferred← citeshttps://doi.org/10.1002/9781119000822.hfcm011.pub2openalex-snapshot
Differentiation Therapy
inferred← citeshttps://doi.org/10.1002/9781119081661.ch10openalex-snapshot
Characterization of Drug–Protein Interactions by Chemoproteomics
inferred← citeshttps://doi.org/10.1002/9781119819950.ch15openalex-snapshot
Quantitating and Characterizing the Effects of Epigenetic Targeted Drugs
inferred← citeshttps://doi.org/10.1002/9783527683604.ch15openalex-snapshot
Epigenetics and Fragment‐Based Drug Discovery
inferred← citeshttps://doi.org/10.1002/9783527687503.ch20openalex-snapshot
Selective Targeting of Protein Interactions Mediated by BET Bromodomains
inferred← citeshttps://doi.org/10.1002/9783527809257.ch13openalex-snapshot
Bromodomains: Promising Targets for Drug Discovery
inferred← citeshttps://doi.org/10.1002/9783527809257.ch4openalex-snapshot
Mass Spectrometry and Chemical Biology in Epigenetics Drug Discovery
inferred← citeshttps://doi.org/10.1002/advs.202300548openalex-snapshot
A T Cell‐Engaging Tumor Organoid Platform for Pancreatic Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1002/advs.202404260openalex-snapshot
Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential
inferred← citeshttps://doi.org/10.1002/ange.201307652openalex-snapshot
4‐Acyl Pyrroles: Mimicking Acetylated Lysines in Histone Code Reading
inferred← citeshttps://doi.org/10.1002/ange.201402750openalex-snapshot
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction
inferred← citeshttps://doi.org/10.1002/ange.201710195openalex-snapshot
Neue Anwendungen der Klick‐Chemie in Zellbiologie und Wirkstoffentwicklung
inferred← citeshttps://doi.org/10.1002/ange.201812164openalex-snapshot
Chemische Epigenetik: der Einfluss chemischer und chemo‐biologischer Techniken auf die Zielstruktur‐Validierung von Bromodomänen
inferred← citeshttps://doi.org/10.1002/anie.201307652openalex-snapshot
4‐Acyl Pyrroles: Mimicking Acetylated Lysines in Histone Code Reading
inferred← citeshttps://doi.org/10.1002/anie.201402750openalex-snapshot
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction
inferred← citeshttps://doi.org/10.1002/anie.201710195openalex-snapshot
Click Chemistry: Novel Applications in Cell Biology and Drug Discovery
inferred← citeshttps://doi.org/10.1002/anie.201812164openalex-snapshot
Chemical Epigenetics: The Impact of Chemical and Chemical Biology Techniques on Bromodomain Target Validation
inferred← citeshttps://doi.org/10.1002/ardp.201400449openalex-snapshot
MLL Leukemia and Future Treatment Strategies
inferred← citeshttps://doi.org/10.1002/ardp.201700147openalex-snapshot
Fragment‐Based Drug Discovery in the Bromodomain and Extra‐Terminal Domain Family
inferred← citeshttps://doi.org/10.1002/art.40194openalex-snapshot
Review: Enhancers in Autoimmune Arthritis: Implications and Therapeutic Potential
inferred← citeshttps://doi.org/10.1002/bies.201200007openalex-snapshot
Menin as a hub controlling mixed lineage leukemia
inferred← citeshttps://doi.org/10.1002/bies.201700247openalex-snapshot
PROTACs: An Emerging Targeting Technique for Protein Degradation in Drug Discovery
inferred← citeshttps://doi.org/10.1002/bies.70006openalex-snapshot
Is Enhancer Function Driven by Protein–Protein Interactions? From Bacteria to Leukemia
inferred← citeshttps://doi.org/10.1002/bmc.5616openalex-snapshot
Acidotic and hypoxic tumor microenvironment induces changes to histone acetylation and methylation in oral squamous cell carcinoma
inferred← citeshttps://doi.org/10.1002/cam4.146openalex-snapshot
BRD 4 associates with p53 in DNMT 3A‐mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ 1
inferred← citeshttps://doi.org/10.1002/cbic.201600184openalex-snapshot
NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains
inferred← citeshttps://doi.org/10.1002/cmdc.201300259openalex-snapshot
Naphthyridines as Novel BET Family Bromodomain Inhibitors
inferred← citeshttps://doi.org/10.1002/cmdc.201300434openalex-snapshot
Bromodomains and Their Pharmacological Inhibitors
inferred← citeshttps://doi.org/10.1002/cmdc.201500540openalex-snapshot
Progress in the Development of non‐BET Bromodomain Chemical Probes
inferred← citeshttps://doi.org/10.1002/cmdc.201600502openalex-snapshot
Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET‐BRET
inferred← citeshttps://doi.org/10.1002/cmdc.201800074openalex-snapshot
Design, Synthesis, and in vitro Biological Evaluation of 3,5‐Dimethylisoxazole Derivatives as BRD4 Inhibitors
inferred← citeshttps://doi.org/10.1002/cmdc.202100731openalex-snapshot
Recent Advances in Dual BRD4‐Kinase Inhibitors Based on Polypharmacology
inferred← citeshttps://doi.org/10.1002/ctm2.181openalex-snapshot
BRD4 regulates self‐renewal ability and tumorigenicity of glioma‐initiating cells by enrichment in the Notch1 promoter region
inferred← citeshttps://doi.org/10.1002/ctm2.933openalex-snapshot
Direct targeted therapy for MLL‐fusion‐driven high‐risk acute leukaemias
inferred← citeshttps://doi.org/10.1002/eji.201444862openalex-snapshot
BET bromodomain inhibition suppresses transcriptional responses to cytokine‐Jak‐STAT signaling in a gene‐specific manner in human monocytes
inferred← citeshttps://doi.org/10.1002/eji.201848081openalex-snapshot
Bromodomain inhibitor I‐BET151 suppresses immune responses during fungal–immune interaction
inferred← citeshttps://doi.org/10.1002/eji.202048945openalex-snapshot
Immunity in acute myeloid leukemia: Where the immune response and targeted therapy meet
inferred← citeshttps://doi.org/10.1002/ejoc.201701772openalex-snapshot
Acid‐Promoted Cascade Reaction of N‐(4‐Chloroquinolin‐3‐yl)carbamates with Amines: One‐Pot Assembly of Imidazo[4,5‐c]quinolin‐2‐ones
inferred← citeshttps://doi.org/10.1002/gcc.22794openalex-snapshot
Transcriptional networks in acute myeloid leukemia
inferred← citeshttps://doi.org/10.1002/hem3.70071openalex-snapshot
Dynamic evolution of TCF3‐PBX1 leukemias at the single‐cell level under chemotherapy pressure
inferred← citeshttps://doi.org/10.1002/hep.30544openalex-snapshot
Aberrant Super‐Enhancer Landscape in Human Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.1002/iid3.150openalex-snapshot
Inhibition of the BET family of epigenetic reader proteins: A novel principle for modulating gene expression in IgE-activated mast cells
inferred← citeshttps://doi.org/10.1002/ijc.33000openalex-snapshot
Co‐targeting bromodomain and extra‐terminal proteins and MCL1 induces synergistic cell death in melanoma
inferred← citeshttps://doi.org/10.1002/ijc.33142openalex-snapshot
Promising strategies: Combination of epigenetic inhibitors for cancer therapy
inferred← citeshttps://doi.org/10.1002/ijch.201400009openalex-snapshot
Molecular Dynamics Simulations of Bromodomains Reveal Binding‐Site Flexibility and Multiple Binding Modes of the Natural Ligand Acetyl‐Lysine
inferred← citeshttps://doi.org/10.1002/jcb.25858openalex-snapshot
Link Between ER-Stress, PPAR-Alpha Activation, and BET Inhibition in Relation to Apolipoprotein A-I Transcription in HepG2 Cells
inferred← citeshttps://doi.org/10.1002/jcb.26264openalex-snapshot
BRD4 promotes gastric cancer progression through the transcriptional and epigenetic regulation of c‐MYC
inferred← citeshttps://doi.org/10.1002/jcb.28005openalex-snapshot
BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML
inferred← citeshttps://doi.org/10.1002/jcp.26010openalex-snapshot
Biological function and histone recognition of family IV bromodomain‐containing proteins
inferred← citeshttps://doi.org/10.1002/jlb.5ri0917-380rropenalex-snapshot
BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment
inferred← citeshttps://doi.org/10.1002/mco2.70728openalex-snapshot
The Histone‐Lysine N‐Methyltransferase (KMT2) Family in Health and Disease
inferred← citeshttps://doi.org/10.1002/med.21730openalex-snapshot
Inhibitors of bromodomain and extra‐terminal proteins for treating multiple human diseases
inferred← citeshttps://doi.org/10.1002/med.21859openalex-snapshot
Dual‐target inhibitors of bromodomain and extra‐terminal proteins in cancer: A review from medicinal chemistry perspectives
inferred← citeshttps://doi.org/10.1002/med.21942openalex-snapshot
Recent progress and structural analyses of domain‐selective BET inhibitors
inferred← citeshttps://doi.org/10.1002/pmic.201300261openalex-snapshot
Chemical proteomic strategies for the discovery and development of anticancer drugs
inferred← citeshttps://doi.org/10.1002/pmic.202200435openalex-snapshot
Proteomics contributions to epigenetic drug discovery
inferred← citeshttps://doi.org/10.1002/prca.201200091openalex-snapshot
The emerging field of chemo‐ and pharmacoproteomics
inferred← citeshttps://doi.org/10.1002/pros.23175openalex-snapshot
Concurrent nuclear ERG and MYC protein overexpression defines a subset of locally advanced prostate cancer: Potential opportunities for synergistic targeted therapeutics
inferred← citeshttps://doi.org/10.1002/pros.24351openalex-snapshot
Novel forms of prostate cancer chemoresistance to successful androgen deprivation therapy demand new approaches: Rationale for targeting BET proteins
inferred← citeshttps://doi.org/10.1002/prot.25818openalex-snapshot
In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4
inferred← citeshttps://doi.org/10.1002/stem.2655openalex-snapshot
Brief Report: Human Acute Myeloid Leukemia Reprogramming to Pluripotency Is a Rare Event and Selects for Patient Hematopoietic Cells Devoid of Leukemic Mutations
inferred← citeshttps://doi.org/10.1002/tcr.201800074openalex-snapshot
Bromodomain Drug Discovery – the Past, the Present, and the Future
inferred← citeshttps://doi.org/10.1002/wrna.1148openalex-snapshot
Mutual relationships between transcription and pre‐mRNA processing in the synthesis of mRNA
inferred← citeshttps://doi.org/10.1002/wrna.1734openalex-snapshot
Emerging roles of BET proteins in transcription and co‐transcriptional RNA processing
inferred← citeshttps://doi.org/10.1007/164_2015_28openalex-snapshot
Emerging Target Families: Intractable Targets
inferred← citeshttps://doi.org/10.1007/978-1-4614-6819-6_3openalex-snapshot
Uncoupling Obesity from Cancer: Bromodomain Co-regulators That Control Inflammatory Networks
inferred← citeshttps://doi.org/10.1007/978-1-4614-7931-4_11openalex-snapshot
Structural Genomics and Drug Discovery for Chromatin-Related Protein Complexes Involved in Histone Tail Recognition
inferred← citeshttps://doi.org/10.1007/978-1-4614-8039-6_11openalex-snapshot
Selective Inhibition of Acetyl-Lysine Effector Domains of the Bromodomain Family in Oncology
inferred← citeshttps://doi.org/10.1007/978-1-4614-8624-4_4openalex-snapshot
Regulating Chromatin by Histone Acetylation
inferred← citeshttps://doi.org/10.1007/978-1-4939-0685-7_19openalex-snapshot
Mapping Protein Complexes Using Covalently Linked Antibodies and Isobaric Mass Tags
inferred← citeshttps://doi.org/10.1007/978-1-62703-269-8_7openalex-snapshot
The Detection of Chromosomal Translocations Involving the Immunoglobulin Loci in B-Cell Malignancies
inferred← citeshttps://doi.org/10.1007/978-3-030-16465-2_28openalex-snapshot
Genetic and Epigenetic Profiling in Personalized Medicine: Advances in Treatment of Acute Myeloid Leukemia
inferred← citeshttps://doi.org/10.1007/978-3-030-80962-1_401-1openalex-snapshot
BET Bromodomain Inhibitors as an Emerging Class of Anticancer Agents
inferred← citeshttps://doi.org/10.1007/978-3-031-62558-9_19openalex-snapshot
Epigenetic Changes Induced by Infectious Agents in Cancer
inferred← citeshttps://doi.org/10.1007/978-3-031-79456-8openalex-snapshot
Semantic Breakthrough in Drug Discovery
inferred← citeshttps://doi.org/10.1007/978-3-032-00771-1_401openalex-snapshot
BET Bromodomain Inhibitors as an Emerging Class of Anticancer Agents
inferred← citeshttps://doi.org/10.1007/978-3-032-12166-0_12openalex-snapshot
Epigenetic alterations in Myeloid Malignancies
inferred← citeshttps://doi.org/10.1007/978-3-319-18102-8_1openalex-snapshot
The Bromodomain as the Acetyl-Lysine Binding Domain in Gene Transcription
inferred← citeshttps://doi.org/10.1007/978-3-319-18102-8_11openalex-snapshot
Activating Latent HIV by Inhibiting Bromodomain Proteins
inferred← citeshttps://doi.org/10.1007/978-3-319-18102-8_9openalex-snapshot
BET Bromodomain Inhibition as a Therapeutic Approach in Hematological Malignancies
inferred← citeshttps://doi.org/10.1007/978-3-319-19983-2_11openalex-snapshot
Cellular and Molecular Basis of KMT2A/MLL Leukaemias: From Transformation Mechanisms to Novel Therapeutic Strategies
inferred← citeshttps://doi.org/10.1007/978-3-319-19983-2_22openalex-snapshot
Aberrant Transcriptional Programming in Blood Cancers
inferred← citeshttps://doi.org/10.1007/978-3-319-41610-6_2openalex-snapshot
Epigenetics, Enhancers, and Cancer
inferred← citeshttps://doi.org/10.1007/978-3-319-42949-6_3openalex-snapshot
Translating STAT Inhibitors from the Lab to the Clinic
inferred← citeshttps://doi.org/10.1007/978-3-319-71553-7_13openalex-snapshot
Signaling Landscape of AML: The Story So Far
inferred← citeshttps://doi.org/10.1007/978-3-642-28965-1_1openalex-snapshot
Protein-Protein Interactions as Drug Targets
inferred← citeshttps://doi.org/10.1007/978-3-642-38404-2_6openalex-snapshot
Epigenetic Modifications Mediated by the AML1/ETO and MLL Leukemia Fusion Proteins
inferred← citeshttps://doi.org/10.1007/978-3-642-45198-0_7openalex-snapshot
Role of the Trithorax (MLL): HOX Axis in HSC Development, Function, and Leukemia
inferred← citeshttps://doi.org/10.1007/978-3-7091-1431-5_2openalex-snapshot
Epigenetic Changes in Gliomas
inferred← citeshttps://doi.org/10.1007/978-4-431-55576-6_12openalex-snapshot
Macrophage Activation as a Model System for Understanding Enhancer Transcription and eRNA Function
inferred← citeshttps://doi.org/10.1007/978-94-007-6621-1_11openalex-snapshot
Transcriptional Regulation of Haematopoietic Stem Cells
inferred← citeshttps://doi.org/10.1007/978-981-15-0548-5_2openalex-snapshot
Genetic Alterations of Pediatric Acute Lymphoblastic Leukemia
inferred← citeshttps://doi.org/10.1007/978-981-15-3449-2_9openalex-snapshot
The Role of Epigenetics in Type 1 Diabetes
inferred← citeshttps://doi.org/10.1007/978-981-32-9620-6_5openalex-snapshot
Epigenetic Regulation in Breast Cancer
inferred← citeshttps://doi.org/10.1007/s00018-017-2620-zopenalex-snapshot
Molecular processes involved in B cell acute lymphoblastic leukaemia
inferred← citeshttps://doi.org/10.1007/s00018-021-03878-8openalex-snapshot
CDK9 keeps RNA polymerase II on track
inferred← citeshttps://doi.org/10.1007/s00018-021-03946-zopenalex-snapshot
Structure–function relationships explain CTCF zinc finger mutation phenotypes in cancer
inferred← citeshttps://doi.org/10.1007/s00018-026-06456-yopenalex-snapshot
An InDel genomic variant within a bifunctional super-enhancer for LINC00636 and CD47 regulation in breast cancer
inferred← citeshttps://doi.org/10.1007/s00044-018-2218-5openalex-snapshot
Development of 7-methylimidazo[1,5-a]pyrazin-8(7H)-one derivatives as a novel chemical series of BRD4 inhibitors
inferred← citeshttps://doi.org/10.1007/s00125-025-06541-0openalex-snapshot
I-BET151 modulates glucokinase gene expression and beta cell function in part through changes in FOXO1 expression
inferred← citeshttps://doi.org/10.1007/s00204-014-1315-6openalex-snapshot
Epigenetic drugs against cancer: an evolving landscape
inferred← citeshttps://doi.org/10.1007/s00210-025-04402-6openalex-snapshot
LncRNA-Histone Modification Crosstalk: Orchestrating Cancer Pathobiology
inferred← citeshttps://doi.org/10.1007/s00216-012-6203-4openalex-snapshot
Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present
inferred← citeshttps://doi.org/10.1007/s00277-013-1803-4openalex-snapshot
MicroRNAs mark in the MLL-rearranged leukemia
inferred← citeshttps://doi.org/10.1007/s00280-015-2766-zopenalex-snapshot
Direct and indirect targeting of MYC to treat acute myeloid leukemia
inferred← citeshttps://doi.org/10.1007/s00412-015-0530-0openalex-snapshot
Chromatin deregulation in disease
inferred← citeshttps://doi.org/10.1007/s00412-021-00762-zopenalex-snapshot
The Trithorax group protein ASH1 requires a combination of BAH domain and AT hooks, but not the SET domain, for mitotic chromatin binding and survival
inferred← citeshttps://doi.org/10.1007/s00740-012-0059-2openalex-snapshot
Epigenetik in der Onkologie
inferred← citeshttps://doi.org/10.1007/s00761-015-2998-xopenalex-snapshot
Epigenetische Strategien in der Krebstherapie
inferred← citeshttps://doi.org/10.1007/s10120-014-0348-0openalex-snapshot
Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer
inferred← citeshttps://doi.org/10.1007/s10555-020-09946-yopenalex-snapshot
Neuroblastoma and the epigenome
inferred← citeshttps://doi.org/10.1007/s11030-016-9707-6openalex-snapshot
Synthesis and biological evaluation of N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)benzenesulfonamide derivatives as new BET bromodomain inhibitors for anti-hematologic malignancies activities
inferred← citeshttps://doi.org/10.1007/s11033-019-04958-6openalex-snapshot
Cell signaling and cancer: a mechanistic insight into drug resistance
inferred← citeshttps://doi.org/10.1007/s11523-017-0503-8openalex-snapshot
Novel Therapies for Acute Myeloid Leukemia: Are We Finally Breaking the Deadlock?
inferred← citeshttps://doi.org/10.1007/s11538-019-00621-0openalex-snapshot
Modeling HIV Dynamics Under Combination Therapy with Inducers and Antibodies
inferred← citeshttps://doi.org/10.1007/s11654-017-0006-1openalex-snapshot
Epigenetische Strategien in der Krebstherapie
inferred← citeshttps://doi.org/10.1007/s11684-017-0604-xopenalex-snapshot
BRD4 interacts with PML/RARα in acute promyelocytic leukemia
inferred← citeshttps://doi.org/10.1007/s11684-020-0780-yopenalex-snapshot
Targeting “undruggable” c-Myc protein by synthetic lethality
inferred← citeshttps://doi.org/10.1007/s11899-021-00621-9openalex-snapshot
Novel Targeted Therapeutics in Acute Myeloid Leukemia: an Embarrassment of Riches
inferred← citeshttps://doi.org/10.1007/s12031-021-01861-3openalex-snapshot
Identification of Four Enhancer-Associated Genes as Risk Signature for Diffuse Glioma Patients
inferred← citeshttps://doi.org/10.1007/s12032-016-0841-xopenalex-snapshot
7SK small nuclear RNA transcription level down-regulates in human tumors and stem cells
inferred← citeshttps://doi.org/10.1007/s12038-016-9600-6openalex-snapshot
Bromodomain and extra-terminal (BET) family proteins: New therapeutic targets in major diseases
inferred← citeshttps://doi.org/10.1007/s12038-019-9969-0openalex-snapshot
The role of histone modifications in leukemogenesis
inferred← citeshttps://doi.org/10.1007/s12039-020-01874-2openalex-snapshot
Synthesis, evaluation and in silico studies of novel BRD4 bromodomain inhibitors bearing a benzo[d]isoxazol scaffold
inferred← citeshttps://doi.org/10.1007/s12094-020-02298-7openalex-snapshot
Precision medicine in Ewing sarcoma: a translational point of view
inferred← citeshttps://doi.org/10.1007/s12185-012-1180-0openalex-snapshot
Disordered epigenetic regulation in MLL-related leukemia
inferred← citeshttps://doi.org/10.1007/s12185-012-1181-zopenalex-snapshot
Epigenetic alterations in hematopoietic malignancies
inferred← citeshttps://doi.org/10.1007/s12308-014-0220-5openalex-snapshot
When and how to test for C-MYC in aggressive B cell lymphomas
inferred← citeshttps://doi.org/10.1007/s13238-021-00846-7openalex-snapshot
Metabolic reprogramming and epigenetic modifications on the path to cancer
inferred← citeshttps://doi.org/10.1007/s13402-014-0177-5openalex-snapshot
The cancer genome: from structure to function
inferred← citeshttps://doi.org/10.1007/s13402-018-0414-4openalex-snapshot
Therapeutic targeting potential of chromatin-associated proteins in MLL-rearranged acute leukemia
inferred← citeshttps://doi.org/10.1007/s40495-018-0130-9openalex-snapshot
Targeting Epigenetic Modifiers for Cancer Treatments
inferred← citeshttps://doi.org/10.1016/b978-0-12-396493-9.00001-7openalex-snapshot
Small Molecule Bromodomain Inhibitors
inferred← citeshttps://doi.org/10.1016/b978-0-12-407707-2.00004-7openalex-snapshot
Logic of the Inflammation-Associated Transcriptional Response
inferred← citeshttps://doi.org/10.1016/b978-0-12-407708-9.00002-9openalex-snapshot
Epigenetic Control of Cytokine Gene Expression
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.12325-xopenalex-snapshot
Novel Therapeutics Targeting Epigenetics
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.12326-1openalex-snapshot
Small-Molecule Inhibitors of Protein–Protein Interactions
inferred← citeshttps://doi.org/10.1016/b978-0-12-410524-9.00001-3openalex-snapshot
Mechanisms of Epigenetic Regulation of Leukemia Onset and Progression
inferred← citeshttps://doi.org/10.1016/b978-0-12-416024-8.00011-8openalex-snapshot
The Role of the Double Bromodomain-Containing BET Genes During Mammalian Spermatogenesis
inferred← citeshttps://doi.org/10.1016/b978-0-12-417150-3.00013-2openalex-snapshot
Recent Advances in Small-Molecule Modulation of Epigenetic Targets
inferred← citeshttps://doi.org/10.1016/b978-0-12-799958-6.00018-4openalex-snapshot
Epigenetic drugs for cancer therapy
inferred← citeshttps://doi.org/10.1016/b978-0-12-800206-3.00003-3openalex-snapshot
Writers, Readers, and Erasers of Epigenetic Marks
inferred← citeshttps://doi.org/10.1016/b978-0-12-800206-3.00022-7openalex-snapshot
Emerging Epigenetic Therapies—Bromodomain Ligands
inferred← citeshttps://doi.org/10.1016/b978-0-12-800206-3.00029-xopenalex-snapshot
Personalized Therapy—Epigenetic Profiling as Predictors of Prognosis and Response
inferred← citeshttps://doi.org/10.1016/b978-0-12-800226-1.00010-1openalex-snapshot
Epigenetics and multiple sclerosis
inferred← citeshttps://doi.org/10.1016/b978-0-12-800802-7.00005-8openalex-snapshot
Clinical Epigenetics of Lung Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-802208-5.00010-2openalex-snapshot
Bromodomains as Anticancer Targets
inferred← citeshttps://doi.org/10.1016/b978-0-12-802389-1.00005-8openalex-snapshot
The Bromodomain as an Acetyl-Lysine Reader Domain
inferred← citeshttps://doi.org/10.1016/b978-0-12-802389-1.00018-6openalex-snapshot
Altered Chromatin Signaling in Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-802808-7.00013-7openalex-snapshot
Computational Structure–Activity Relationship Studies of Epigenetic Target Inhibitors
inferred← citeshttps://doi.org/10.1016/b978-0-12-803239-8.00012-0openalex-snapshot
Immune System Disorders and Epigenetics
inferred← citeshttps://doi.org/10.1016/b978-0-12-803395-1.00002-2openalex-snapshot
Histone Modifications and Histone Variants in Pluripotency and Differentiation
inferred← citeshttps://doi.org/10.1016/b978-0-12-812215-0.00006-6openalex-snapshot
Alterations of Histone Modifications in Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-813939-4.00011-5openalex-snapshot
Bromodomain Inhibition and Its Application to Human Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-813939-4.00012-7openalex-snapshot
Epigenetic Drug Discovery for Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-816422-8.00006-4openalex-snapshot
BET mechanisms in cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-816422-8.00016-7openalex-snapshot
Targeting histone modifications in cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/b978-0-12-819753-0.00019-2openalex-snapshot
Epigenetics in diagnosis, prognosis and therapy
inferred← citeshttps://doi.org/10.1016/b978-0-12-821909-6.00008-0openalex-snapshot
Targeting YY1 in cancer through histone acetylation
inferred← citeshttps://doi.org/10.1016/b978-0-12-823928-5.00013-xopenalex-snapshot
Clinical utility of solid tumor epigenetics
inferred← citeshttps://doi.org/10.1016/b978-0-323-91367-6.00017-9openalex-snapshot
Epigenetic targeted therapies in hematological malignancies
inferred← citeshttps://doi.org/10.1016/b978-0-443-18722-3.00046-3openalex-snapshot
Epigenetic drug discovery for cancer
inferred← citeshttps://doi.org/10.1016/b978-0-443-19001-8.00024-6openalex-snapshot
Altered chromatin signaling in cancer
inferred← citeshttps://doi.org/10.1016/b978-0-443-31592-3.00018-2openalex-snapshot
Epigenetic modulators in cancer therapy: Treatment and beyond
inferred← citeshttps://doi.org/10.1016/b978-1-4557-2865-7.00096-5openalex-snapshot
Childhood Leukemia
inferred← citeshttps://doi.org/10.1016/b978-1-4557-4066-6.00005-6openalex-snapshot
Epigenetics and Cancer
inferred← citeshttps://doi.org/10.1016/b978-1-4557-5414-4.00044-9openalex-snapshot
10.1016/b978-1-4557-5414-4.00044-9
inferred← citeshttps://doi.org/10.1016/bs.acc.2019.11.002openalex-snapshot
New biomarkers in non-Hodgkin lymphoma and acute leukemias
inferred← citeshttps://doi.org/10.1016/bs.acr.2015.09.003openalex-snapshot
Hsp90 as a “Chaperone” of the Epigenome
inferred← citeshttps://doi.org/10.1016/bs.acr.2016.04.001openalex-snapshot
Small-Molecule Targeting of BET Proteins in Cancer
inferred← citeshttps://doi.org/10.1016/bs.mie.2016.01.018openalex-snapshot
Preparation, Biochemical Analysis, and Structure Determination of the Bromodomain, an Acetyl-Lysine Binding Domain
inferred← citeshttps://doi.org/10.1016/j.aca.2024.342513openalex-snapshot
Exploring affinity chromatography in proteomics: A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.adcanc.2021.100024openalex-snapshot
Relation between tumor micro-environment and epigenetic alterations in hematological malignancies
inferred← citeshttps://doi.org/10.1016/j.addr.2015.10.006openalex-snapshot
Targeting cancer epigenetics: Linking basic biology to clinical medicine
inferred← citeshttps://doi.org/10.1016/j.ajpath.2018.02.006openalex-snapshot
Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration
inferred← citeshttps://doi.org/10.1016/j.antiviral.2018.03.012openalex-snapshot
BET bromodomain inhibitors show anti-papillomavirus activity in vitro and block CRPV wart growth in vivo
inferred← citeshttps://doi.org/10.1016/j.apsb.2025.08.022openalex-snapshot
The epigenetic landscape of rheumatoid arthritis: Pathogenesis and drug therapeutic potentials
inferred← citeshttps://doi.org/10.1016/j.bbadis.2014.05.013openalex-snapshot
I-BET151 selectively regulates IL-6 production
inferred← citeshttps://doi.org/10.1016/j.bbadis.2020.165923openalex-snapshot
Bromodomain and Extraterminal (BET) protein inhibition suppresses tumor progression and inhibits HGF-MET signaling through targeting cancer-associated fibroblasts in colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2015.09.008openalex-snapshot
Histone H1 alterations in cancer
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2020.194503openalex-snapshot
MLL fusion proteins and transcriptional control
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2020.194547openalex-snapshot
The reciprocal world of MLL fusions: A personal view
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2020.194550openalex-snapshot
Learning from mouse models of MLL fusion gene-driven acute leukemia
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2020.194560openalex-snapshot
The complex activities of the SET1/MLL complex core subunits in development and disease
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2020.194564openalex-snapshot
MLL-rearranged infant leukaemia: A ‘thorn in the side’ of a remarkable success story
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2020.194584openalex-snapshot
Novel therapeutic strategies for MLL-rearranged leukemias
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2022.194859openalex-snapshot
Catching BETs by viruses
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2017.09.009openalex-snapshot
The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability
inferred← citeshttps://doi.org/10.1016/j.bbcan.2012.02.002openalex-snapshot
ETV1, 4 and 5: An oncogenic subfamily of ETS transcription factors
inferred← citeshttps://doi.org/10.1016/j.bbcan.2014.08.006openalex-snapshot
MYC deregulation in lymphoid tumors: molecular mechanisms, clinical consequences and therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.bbcan.2015.02.002openalex-snapshot
Transcription factors and chromatin proteins as therapeutic targets in cancer
inferred← citeshttps://doi.org/10.1016/j.bbcan.2022.188697openalex-snapshot
Super enhancers as master gene regulators in the pathogenesis of hematologic malignancies
inferred← citeshttps://doi.org/10.1016/j.bbrc.2012.10.112openalex-snapshot
BET bromodomain inhibition rescues erythropoietin differentiation of human erythroleukemia cell line UT7
inferred← citeshttps://doi.org/10.1016/j.bbrc.2014.08.004openalex-snapshot
Somatic alterations and dysregulation of epigenetic modifiers in cancers
showing the first 200 of 1481 · page through all 1481
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.