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PIK3CAH1047R induces multipotency and multi-lineage mammary tumours
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/path.4096openalex-snapshot
Developmental stage‐specific contribution of LGR5 + cells to basal and luminal epithelial lineages in the postnatal mammary gland
inferredcites →https://doi.org/10.1016/j.cell.2009.06.048openalex-snapshot
The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells
inferredcites →https://doi.org/10.1016/j.celrep.2012.12.017openalex-snapshot
Lgr5-Expressing Cells Are Sufficient and Necessary for Postnatal Mammary Gland Organogenesis
inferredcites →https://doi.org/10.1016/j.jim.2009.06.008openalex-snapshot
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
inferredcites →https://doi.org/10.1016/j.stem.2010.07.010openalex-snapshot
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
inferredcites →https://doi.org/10.1016/j.stem.2011.12.018openalex-snapshot
A Mammary Stem Cell Population Identified and Characterized in Late Embryogenesis Reveals Similarities to Human Breast Cancer
inferredcites →https://doi.org/10.1016/j.stem.2012.05.023openalex-snapshot
Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland
inferredcites →https://doi.org/10.1016/j.stemcr.2014.04.004openalex-snapshot
Lineage Tracing of Mammary Epithelial Cells Using Cell-Type-Specific Cre-Expressing Adenoviruses
inferredcites →https://doi.org/10.1016/j.ydbio.2014.03.009openalex-snapshot
Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice
inferredcites →https://doi.org/10.1016/s1534-5807(01)00064-8openalex-snapshot
Signaling Pathways in Mammary Gland Development
inferredcites →https://doi.org/10.1038/nature04372openalex-snapshot
Generation of a functional mammary gland from a single stem cell
inferredcites →https://doi.org/10.1038/nature04496openalex-snapshot
Purification and unique properties of mammary epithelial stem cells
inferredcites →https://doi.org/10.1038/nature10573openalex-snapshot
Distinct stem cells contribute to mammary gland development and maintenance
inferredcites →https://doi.org/10.1038/nature11412openalex-snapshot
Comprehensive molecular portraits of human breast tumours
inferredcites →https://doi.org/10.1038/nature12948openalex-snapshot
In situ identification of bipotent stem cells in the mammary gland
inferredcites →https://doi.org/10.1038/nature13851openalex-snapshot
Identification of multipotent mammary stem cells by protein C receptor expression
inferredcites →https://doi.org/10.1038/ncb3025openalex-snapshot
Mammary stem cells have myoepithelial cell properties
inferredcites →https://doi.org/10.1038/nm.2000openalex-snapshot
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
inferredcites →https://doi.org/10.1038/nm.2402openalex-snapshot
Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway–dependent and PI3K pathway–independent mechanisms
inferredcites →https://doi.org/10.1038/oncsis.2013.38openalex-snapshot
Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R
inferredcites →https://doi.org/10.1083/jcb.200604065openalex-snapshot
Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland
inferredcites →https://doi.org/10.1093/bioinformatics/btq431openalex-snapshot
A framework for oligonucleotide microarray preprocessing
inferredcites →https://doi.org/10.1093/nar/gkh073openalex-snapshot
Database resources of the National Center for Biotechnology Information: update
inferredcites →https://doi.org/10.1093/nar/gkt1146openalex-snapshot
Database resources of the National Center for Biotechnology Information
inferredcites →https://doi.org/10.1109/isbi.2011.5872394openalex-snapshot
Ilastik: Interactive learning and segmentation toolkit
inferredcites →https://doi.org/10.1111/febs.12175openalex-snapshot
Mouse models of PIK 3 CA mutations: one mutation initiates heterogeneous mammary tumors
inferredcites →https://doi.org/10.1126/science.1096502openalex-snapshot
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
inferredcites →https://doi.org/10.1158/0008-5472.can-10-3827openalex-snapshot
Luminal Expression of PIK3CA Mutant H1047R in the Mammary Gland Induces Heterogeneous Tumors
inferredcites →https://doi.org/10.1159/000353099openalex-snapshot
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
inferredcites →https://doi.org/10.1159/000453569openalex-snapshot
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
inferredcites →https://doi.org/10.1186/1471-2105-11-367openalex-snapshot
A flexible R package for nonnegative matrix factorization
inferredcites →https://doi.org/10.1186/bcr1371openalex-snapshot
CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells
inferredcites →https://doi.org/10.1186/bcr2560openalex-snapshot
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
inferredcites →https://doi.org/10.1186/bcr3419openalex-snapshot
Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Single-Cell Transcriptomic Analysis of Mammary Tumors Reveals Distinct Patterns of Hierarchical and Subtype Heterogeneity
inferred← citeshttps://doi.org/10.1002/1878-0261.12053openalex-snapshot
Inhibitors of STAT 3, β‐catenin, and IGF ‐1R sensitize mouse PIK 3 CA ‐mutant breast cancer to PI 3K inhibitors
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Engineered crRNA Drives RPA‐T7‐CRISPR/Cas14a Cascade for Ultrasensitive Detection of ctDNA PIK3CA H1047R
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Tissue disruption increases stochastic gene expression thus producing tumors: Cancer initiation without driver mutation
inferred← citeshttps://doi.org/10.1002/ijc.32522openalex-snapshot
GLI1‐induced mammary gland tumours are transplantable and maintain major molecular features
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inferred← citeshttps://doi.org/10.1007/82_2017_6openalex-snapshot
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Estrogen receptor-α signaling in post-natal mammary development and breast cancers
inferred← citeshttps://doi.org/10.1007/s00109-015-1352-5openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10539-018-9629-zopenalex-snapshot
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Transcriptome- and proteome-oriented identification of dysregulated eIF4G, STAT3, and Hippo pathways altered by PIK3CA H1047R in HER2/ER-positive breast cancer
inferred← citeshttps://doi.org/10.1007/s10549-022-06570-yopenalex-snapshot
PIK3CA-AKT pathway predominantly acts in developing ipsilateral breast tumor recurrence long after breast-conserving surgery
inferred← citeshttps://doi.org/10.1007/s10549-022-06731-zopenalex-snapshot
TP53-positive clones are responsible for drug-tolerant persister and recurrence of HER2-positive breast cancer
inferred← citeshttps://doi.org/10.1007/s10911-018-9412-4openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10911-020-09470-3openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10911-023-09544-yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s10911-025-09584-6openalex-snapshot
Intraductal Injection of Adenoviruses to Perform Lineage Tracing in the Mammary Gland
inferred← citeshttps://doi.org/10.1007/s10911-025-09586-4openalex-snapshot
Reactivation of Multipotency in the Mammary Gland – a Ripple in the Pond and a Turn of the Tide
inferred← citeshttps://doi.org/10.1007/s10911-025-09592-6openalex-snapshot
BRCA1: An Unrecognized Modulator of Lineage Plasticity in Basal-like Breast Cancer
inferred← citeshttps://doi.org/10.1007/s10911-026-09595-xopenalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s11684-018-0656-6openalex-snapshot
Epithelial-to-mesenchymal transition in cancer: complexity and opportunities
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Comprehensive Review on the Effect of Stem Cells in Cancer Progression
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Tumor Heterogeneity
inferred← citeshttps://doi.org/10.1016/b978-0-12-812034-7.00020-0openalex-snapshot
Combination Therapies in Solid Tumour Oncology
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Introduction to breast cancer stem cells and tumor heterogeneity
inferred← citeshttps://doi.org/10.1016/j.bbadis.2024.167226openalex-snapshot
Heterogeneity generating capacity in tumorigenesis and cancer therapeutics
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Mammary basal cells: Stars of the show
inferred← citeshttps://doi.org/10.1016/j.canlet.2026.218799openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.ccell.2018.12.002openalex-snapshot
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Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging
inferred← citeshttps://doi.org/10.1016/j.ceb.2016.07.005openalex-snapshot
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In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111759openalex-snapshot
The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
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ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen
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Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
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TP53-based tripartite classification reveals three distinct mutation patterns across pan-cancer
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FGD5 in basal cells induces CXCL14 secretion that initiates a feedback loop to promote murine mammary epithelial growth and differentiation
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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders
inferred← citeshttps://doi.org/10.1016/j.molonc.2016.07.005openalex-snapshot
Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2‐negative metastatic breast cancer
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SOX factors as cell-state regulators in the mammary gland and breast cancer
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Cryo-EM structures reveal two allosteric inhibition modes of PI3KαH1047R involving a re-shaping of the activation loop
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inferred← citeshttps://doi.org/10.1016/j.tcb.2023.03.010openalex-snapshot
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IGF1R constitutive activation expands luminal progenitors and influences lineage differentiation during breast tumorigenesis
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The extracellular matrix in breast cancer predicts prognosis through composition, splicing, and crosslinking
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The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα
inferred← citeshttps://doi.org/10.1038/ncb3434openalex-snapshot
Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours
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Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma
inferred← citeshttps://doi.org/10.1038/ncomms11479openalex-snapshot
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes
inferred← citeshttps://doi.org/10.1038/ncomms13053openalex-snapshot
Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny
inferred← citeshttps://doi.org/10.1038/ncomms14431openalex-snapshot
Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours
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Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition
inferred← citeshttps://doi.org/10.1038/s12276-026-01869-yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1038/s41379-020-0589-xopenalex-snapshot
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inferred← citeshttps://doi.org/10.1038/s41388-020-01508-4openalex-snapshot
Multi-color clonal tracking reveals intra-stage proliferative heterogeneity during mammary tumor progression
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Breast cancer as an example of tumour heterogeneity and tumour cell plasticity during malignant progression
inferred← citeshttps://doi.org/10.1038/s41416-022-02021-zopenalex-snapshot
PIK3CA mutations are associated with pathologic complete response rate to neoadjuvant pyrotinib and trastuzumab plus chemotherapy for HER2-positive breast cancer
inferred← citeshttps://doi.org/10.1038/s41420-018-0072-3openalex-snapshot
Combined effects of FH (E404D) and ACOX2 (R409H) cause metabolic defects in primary cardiac malignant tumor
inferred← citeshttps://doi.org/10.1038/s41422-018-0137-0openalex-snapshot
Hormones induce the formation of luminal-derived basal cells in the mammary gland
inferred← citeshttps://doi.org/10.1038/s41467-017-01971-wopenalex-snapshot
Long-lived unipotent Blimp1-positive luminal stem cells drive mammary gland organogenesis throughout adult life
inferred← citeshttps://doi.org/10.1038/s41467-018-03264-2openalex-snapshot
MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state
inferred← citeshttps://doi.org/10.1038/s41467-018-04128-5openalex-snapshot
Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas
inferred← citeshttps://doi.org/10.1038/s41467-020-17249-7openalex-snapshot
Comprehensive characterization of claudin-low breast tumors reflects the impact of the cell-of-origin on cancer evolution
inferred← citeshttps://doi.org/10.1038/s41467-020-18701-4openalex-snapshot
Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency
inferred← citeshttps://doi.org/10.1038/s41467-021-24836-9openalex-snapshot
Canine tumor mutational burden is correlated with TP53 mutation across tumor types and breeds
inferred← citeshttps://doi.org/10.1038/s41467-021-25240-zopenalex-snapshot
Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast
inferred← citeshttps://doi.org/10.1038/s41467-022-34863-9openalex-snapshot
Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis
inferred← citeshttps://doi.org/10.1038/s41467-022-34864-8openalex-snapshot
Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas
inferred← citeshttps://doi.org/10.1038/s41467-024-54843-5openalex-snapshot
Collagen signaling and matrix stiffness regulate multipotency in glandular epithelial stem cells in mice
inferred← citeshttps://doi.org/10.1038/s41467-026-70020-2openalex-snapshot
Rank signaling drives basal cell-lineage infidelity leading to mammary tumorigenesis
inferred← citeshttps://doi.org/10.1038/s41523-017-0012-zopenalex-snapshot
Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity
inferred← citeshttps://doi.org/10.1038/s41523-020-00175-8openalex-snapshot
Integrating single-cell RNA-sequencing and functional assays to decipher mammary cell states and lineage hierarchies
inferred← citeshttps://doi.org/10.1038/s41523-020-0165-zopenalex-snapshot
Somatic genetic aberrations in benign breast disease and the risk of subsequent breast cancer
inferred← citeshttps://doi.org/10.1038/s41523-026-00928-xopenalex-snapshot
Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance
inferred← citeshttps://doi.org/10.1038/s41556-018-0108-1openalex-snapshot
Clonal analysis of Notch1-expressing cells reveals the existence of unipotent stem cells that retain long-term plasticity in the embryonic mammary gland
inferred← citeshttps://doi.org/10.1038/s41556-018-0111-6openalex-snapshot
Mammary lineage restriction in development
inferred← citeshttps://doi.org/10.1038/s41556-024-01409-8openalex-snapshot
Cell-intrinsic and microenvironmental determinants of metastatic colonization
inferred← citeshttps://doi.org/10.1038/s41568-021-00332-6openalex-snapshot
Linking EMT programmes to normal and neoplastic epithelial stem cells
inferred← citeshttps://doi.org/10.1038/s41568-022-00512-yopenalex-snapshot
Learning to distinguish progressive and non-progressive ductal carcinoma in situ
inferred← citeshttps://doi.org/10.1038/s41568-025-00873-0openalex-snapshot
Identification, functional insights and therapeutic targeting of EMT tumour states
inferred← citeshttps://doi.org/10.1038/s41586-020-2632-yopenalex-snapshot
Heterotypic cell–cell communication regulates glandular stem cell multipotency
inferred← citeshttps://doi.org/10.1038/s41586-024-07882-3openalex-snapshot
Mechanisms that clear mutations drive field cancerization in mammary tissue
inferred← citeshttps://doi.org/10.1038/s41588-025-02289-wopenalex-snapshot
ERG-driven prostate cancer initiation is cell-context dependent and requires KMT2A and DOT1L
inferred← citeshttps://doi.org/10.1038/s41596-019-0234-7openalex-snapshot
Analysis pipelines for cancer genome sequencing in mice
inferred← citeshttps://doi.org/10.1038/s41598-017-11666-3openalex-snapshot
Altered Adipose-Derived Stem Cell Characteristics in Macrodactyly
inferred← citeshttps://doi.org/10.1038/s41598-018-22473-9openalex-snapshot
A simple and robust real-time qPCR method for the detection of PIK3CA mutations
inferred← citeshttps://doi.org/10.1038/s41598-018-35619-6openalex-snapshot
Disulfiram and BKM120 in Combination with Chemotherapy Impede Tumor Progression and Delay Tumor Recurrence in Tumor Initiating Cell-Rich TNBC
inferred← citeshttps://doi.org/10.1038/s41598-020-73164-3openalex-snapshot
Assessing the prognostic value of stemness-related genes in breast cancer patients
inferred← citeshttps://doi.org/10.1038/s41598-026-43069-8openalex-snapshot
Transient adenovirus-Cre infection causes long-lasting remodeling of the mammary gland immune landscape
inferred← citeshttps://doi.org/10.1038/s42003-021-01959-9openalex-snapshot
Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast
inferred← citeshttps://doi.org/10.1038/s42003-022-03161-xopenalex-snapshot
Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation
inferred← citeshttps://doi.org/10.1038/s42255-021-00388-6openalex-snapshot
Mammary epithelial cells have lineage-rooted metabolic identities
inferred← citeshttps://doi.org/10.1038/s43018-023-00595-yopenalex-snapshot
Cancer cell plasticity during tumor progression, metastasis and response to therapy
inferred← citeshttps://doi.org/10.1038/s43018-024-00839-5openalex-snapshot
Two distinct epithelial-to-mesenchymal transition programs control invasion and inflammation in segregated tumor cell populations
inferred← citeshttps://doi.org/10.1038/s44318-025-00424-1openalex-snapshot
Transcriptional landscapes underlying Notch-induced lineage conversion and plasticity of mammary basal cells
inferred← citeshttps://doi.org/10.1038/s44320-024-00078-xopenalex-snapshot
Oncogenic PIK3CA corrupts growth factor signaling specificity
inferred← citeshttps://doi.org/10.1038/sigtrans.2016.38openalex-snapshot
Mammary stem cells: angels or demons in mammary gland?
inferred← citeshttps://doi.org/10.1042/bst20190778openalex-snapshot
PI3K in stemness regulation: from development to cancer
inferred← citeshttps://doi.org/10.1063/1.5058278openalex-snapshot
Letter: Evolution of coherent vortical structures in a shock wave/turbulent boundary-layer interaction flow
inferred← citeshttps://doi.org/10.1073/pnas.1603645113openalex-snapshot
Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay
inferred← citeshttps://doi.org/10.1073/pnas.1714063114openalex-snapshot
Proof of region-specific multipotent progenitors in human breast epithelia
inferred← citeshttps://doi.org/10.1073/pnas.1803177115openalex-snapshot
BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexes
inferred← citeshttps://doi.org/10.1073/pnas.1821093116openalex-snapshot
Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner
inferred← citeshttps://doi.org/10.1080/15384101.2015.1062330openalex-snapshot
Stem cell division theory of cancer
inferred← citeshttps://doi.org/10.1080/15384101.2015.1121351openalex-snapshot
MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures
inferred← citeshttps://doi.org/10.1083/jcb.202112001openalex-snapshot
Aberrant phosphorylation inactivates Numb in breast cancer causing expansion of the stem cell pool
inferred← citeshttps://doi.org/10.1089/ars.2015.6546openalex-snapshot
Breast Cancer: A Molecular and Redox Snapshot
inferred← citeshttps://doi.org/10.1089/dna.2017.3981openalex-snapshot
Clinical Applications of and Challenges in Single-Cell Analysis of Circulating Tumor Cells
inferred← citeshttps://doi.org/10.1093/med/9780192867636.003.0010openalex-snapshot
Modelling phenotypic heterogeneity and cell-state transitions during cancer progression
inferred← citeshttps://doi.org/10.1093/neuonc/now073.72openalex-snapshot
HG-76SPATIAL AND TEMPORAL HOMOGENEITY OF DRIVER MUTATIONS IN DIFFUSE INTRINSIC PONTINE GLIOMA
inferred← citeshttps://doi.org/10.1097/mog.0000000000001005openalex-snapshot
Biliary stem cells in health and cholangiopathies and cholangiocarcinoma
inferred← citeshttps://doi.org/10.1101/2020.06.05.136192openalex-snapshot
A Genome-wide Library of MADM Mice for Single-Cell Genetic Mosaic Analysis
inferred← citeshttps://doi.org/10.1101/2020.07.09.195974openalex-snapshot
Transcriptomically-inferred PI3K activity and stemness show a counterintuitive correlation with PIK3CA genotype in breast cancer
inferred← citeshttps://doi.org/10.1101/2020.09.10.291872openalex-snapshot
Fine-tuning of Epithelial EGFR signals Supports Coordinated Mammary Gland Development
inferred← citeshttps://doi.org/10.1101/2021.06.22.449401openalex-snapshot
In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation
inferred← citeshttps://doi.org/10.1101/2021.06.22.449461openalex-snapshot
Hyperactive WNT/CTNNB1 signaling induces a competing cell proliferation and epidermal differentiation response in the mouse mammary epithelium
inferred← citeshttps://doi.org/10.1101/2021.10.22.465428openalex-snapshot
Loss of epigenetic regulation disrupts lineage integrity, reactivates multipotency and promotes breast cancer
inferred← citeshttps://doi.org/10.1101/2023.12.23.573207openalex-snapshot
Oncogenic PIK3CA corrupts growth factor signaling specificity
inferred← citeshttps://doi.org/10.1101/2024.08.01.606240openalex-snapshot
Pregnancy Reduces Il33+ Hybrid Progenitor Accumulation in the Aged Mammary Gland
inferred← citeshttps://doi.org/10.1101/2025.02.25.640041openalex-snapshot
Context-dependent response of endothelial cells to PIK3CA mutation
inferred← citeshttps://doi.org/10.1101/270975openalex-snapshot
Classification of breast tumours into molecular apocrine, luminal and basal groups based on an explicit biological model
inferred← citeshttps://doi.org/10.1101/430611openalex-snapshot
Changes in epithelial proportions and transcriptional state underlie major premenopausal breast cancer risks
inferred← citeshttps://doi.org/10.1101/gad.280057.116openalex-snapshot
Quantitative lineage tracing strategies to resolve multipotency in tissue-specific stem cells
inferred← citeshttps://doi.org/10.1111/bpa.12348openalex-snapshot
Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models
inferred← citeshttps://doi.org/10.1111/vco.12917openalex-snapshot
New molecular targets in canine hemangiosarcoma—Comparative review and future of the precision medicine
inferred← citeshttps://doi.org/10.1124/pr.118.016253openalex-snapshot
Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health
inferred← citeshttps://doi.org/10.1126/sciadv.ade0059openalex-snapshot
Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice
inferred← citeshttps://doi.org/10.1126/sciadv.adk8958openalex-snapshot
Tumor suppressor FRMD3 controls mammary epithelial cell fate determination via notch signaling pathway
inferred← citeshttps://doi.org/10.1126/scisignal.aad5856openalex-snapshot
Oncogenic PI3Kα promotes multipotency in breast epithelial cells
inferred← citeshttps://doi.org/10.1126/scisignal.aay2940openalex-snapshot
Cracking the context-specific PI3K signaling code
inferred← citeshttps://doi.org/10.1146/annurev-cancerbio-051320-124252openalex-snapshot
Mutant Allele Imbalance in Cancer
inferred← citeshttps://doi.org/10.1146/annurev-pathmechdis-031621-025610openalex-snapshot
Cancer as a Disease of Development Gone Awry
inferred← citeshttps://doi.org/10.1152/physrev.00024.2015openalex-snapshot
Acquired Resistance to Clinical Cancer Therapy: A Twist in Physiological Signaling
inferred← citeshttps://doi.org/10.1152/physrev.00040.2018openalex-snapshot
Stem Cells and the Differentiation Hierarchy in Mammary Gland Development
inferred← citeshttps://doi.org/10.1155/2018/4598195openalex-snapshot
Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and Epigenetics
inferred← citeshttps://doi.org/10.1155/2019/4247168openalex-snapshot
Stem Cells and Cellular Origins of Mammary Gland: Updates in Rationale, Controversies, and Cancer Relevance
inferred← citeshttps://doi.org/10.11575/prism/28345openalex-snapshot
The Role of PIK3CA in Cisplatin Resistance of Cervical Cancer
inferred← citeshttps://doi.org/10.1158/0008-5472.can-17-0985openalex-snapshot
Antiestrogen Therapy Increases Plasticity and Cancer Stemness of Prolactin-Induced ERα+ Mammary Carcinomas
inferred← citeshttps://doi.org/10.1158/0008-5472.can-18-1087openalex-snapshot
Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes
inferred← citeshttps://doi.org/10.1158/0008-5472.can-19-1242openalex-snapshot
Targeting Cancer Cell Metastasis by Converting Cancer Cells into Fat
inferred← citeshttps://doi.org/10.1158/1541-7786.mcr-21-0215openalex-snapshot
HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase
inferred← citeshttps://doi.org/10.1158/1940-6207.c.6547696.v1openalex-snapshot
Data from Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer
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