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Correction of aberrant growth preserves tissue homeostasis
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/dvg.20397openalex-snapshot
A CK19CreERT knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs
inferredcites →https://doi.org/10.1002/dvg.20651openalex-snapshot
Generation of mice with a conditional null allele for Wntless
inferredcites →https://doi.org/10.1002/emmm.201100186openalex-snapshot
The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis
inferredcites →https://doi.org/10.1007/978-1-62703-227-8_23openalex-snapshot
RNAi-Mediated Gene Function Analysis in Skin
inferredcites →https://doi.org/10.1016/j.cell.2006.10.018openalex-snapshot
Wnt/β-Catenin Signaling in Development and Disease
inferredcites →https://doi.org/10.1016/j.cell.2011.01.014openalex-snapshot
The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche
inferredcites →https://doi.org/10.1016/j.celrep.2015.12.041openalex-snapshot
Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity
inferredcites →https://doi.org/10.1016/j.devcel.2009.06.016openalex-snapshot
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
inferredcites →https://doi.org/10.1016/j.stem.2012.05.023openalex-snapshot
Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland
inferredcites →https://doi.org/10.1016/j.stemcr.2015.09.013openalex-snapshot
Dynamics of Lgr6 + Progenitor Cells in the Hair Follicle, Sebaceous Gland, and Interfollicular Epidermis
inferredcites →https://doi.org/10.1016/j.ydbio.2010.04.005openalex-snapshot
Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation
inferredcites →https://doi.org/10.1016/s0002-9440(10)62511-4openalex-snapshot
Persistent p53 Mutations in Single Cells from Normal Human Skin
inferredcites →https://doi.org/10.1016/s0092-8674(00)81631-1openalex-snapshot
De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin
inferredcites →https://doi.org/10.1038/7747openalex-snapshot
A common human skin tumour is caused by activating mutations in β-catenin
inferredcites →https://doi.org/10.1038/nature11218openalex-snapshot
Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration
inferredcites →https://doi.org/10.1038/nature14306openalex-snapshot
Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool
inferredcites →https://doi.org/10.1038/ncomms3626openalex-snapshot
Cdkn1b overexpression in adult mice alters the balance between genome and tissue ageing
inferredcites →https://doi.org/10.1038/ng.2271openalex-snapshot
Detectable clonal mosaicism from birth to old age and its relationship to cancer
inferredcites →https://doi.org/10.1038/nm.2167openalex-snapshot
Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos
inferredcites →https://doi.org/10.1038/nn.2467openalex-snapshot
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
inferredcites →https://doi.org/10.1038/nprot.2015.070openalex-snapshot
Intravital imaging of hair follicle regeneration in the mouse
inferredcites →https://doi.org/10.1038/sj.mt.6300332openalex-snapshot
Efficient In Vivo Targeting of Epidermal Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector Driven by the Keratin 5 Promoter
inferredcites →https://doi.org/10.1038/sj.onc.1202673openalex-snapshot
Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFα expression in transgenic mice
inferredcites →https://doi.org/10.1073/pnas.0900343106openalex-snapshot
Endogenous expression of Hras G12V induces developmental defects and neoplasms with copy number imbalances of the oncogene
inferredcites →https://doi.org/10.1093/emboj/18.21.5931openalex-snapshot
Intestinal polyposis in mice with a dominant stable mutation of the β‐catenin gene
inferredcites →https://doi.org/10.1101/gad.1115203openalex-snapshot
GATA-3: an unexpected regulator of cell lineage determination in skin
inferredcites →https://doi.org/10.1126/science.1092436openalex-snapshot
Defining the Epithelial Stem Cell Niche in Skin
inferredcites →https://doi.org/10.1126/science.1184733openalex-snapshot
Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin
inferredcites →https://doi.org/10.1126/science.1233029openalex-snapshot
Sept4/ ARTS Regulates Stem Cell Apoptosis and Skin Regeneration
inferredcites →https://doi.org/10.1126/science.1248373openalex-snapshot
β-Catenin Activation Regulates Tissue Growth Non–Cell Autonomously in the Hair Stem Cell Niche
inferredcites →https://doi.org/10.1126/science.275.5307.1787openalex-snapshot
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
inferredcites →https://doi.org/10.1126/science.aaa6806openalex-snapshot
High burden and pervasive positive selection of somatic mutations in normal human skin
inferredcites →https://doi.org/10.1177/0022034510370090openalex-snapshot
β-catenin Initiates Tooth Neogenesis in Adult Rodent Incisors
inferredcites →https://doi.org/10.1186/1471-213x-10-121openalex-snapshot
A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse
inferredcites →https://doi.org/10.1242/dev.01052openalex-snapshot
Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1016/j.semcancer.2018.02.010openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.semcancer.2019.06.010openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.semcancer.2019.07.008openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.semcancer.2023.04.002openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.stem.2018.10.019openalex-snapshot
Epidermal Darwinism and Competitive Equilibrium within the Epidermis
inferred← citeshttps://doi.org/10.1016/j.stem.2019.08.006openalex-snapshot
Changing the Rules of the Game: How Winners Become Losers during Oncogenic Cell Selection
inferred← citeshttps://doi.org/10.1016/j.stem.2020.03.015openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.stem.2020.05.007openalex-snapshot
Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress
inferred← citeshttps://doi.org/10.1016/j.stemcr.2017.09.022openalex-snapshot
Covering the Stem Cell Explosion at the 2017 ISSCR Conference in Boston
inferred← citeshttps://doi.org/10.1016/j.tcb.2018.05.002openalex-snapshot
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Extracellular serine controls epidermal stem cell fate and tumour initiation
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Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation
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Hair follicle regeneration suppresses Ras-driven oncogenic growth
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Adult hair follicles keep oncogenic growth in check
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Cell competition in tumorigenesis and epithelial defence against cancer
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Wnt-mediated interactions of tumor-initiating cells with a macrophage niche drive skin tumor formation
inferred← citeshttps://doi.org/10.1101/2022.11.21.517380openalex-snapshot
Differential metabolic adaptations define responses of winner and loser oncogenic mutant stem cells in skin epidermis in vivo
inferred← citeshttps://doi.org/10.1101/2024.05.15.593526openalex-snapshot
Heterotypic competition between cancer cells and hepatocytes generates heterogeneous context-dependent phenotypes
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Stromal KITL/SCF promotes pancreas tissue homeostasis and restrains tumor progression
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Tumor establishment requires tumor autonomous and non-autonomous deregulation of homeostatic feedback control
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Stem Cell DNA Damage and Genome Mutation in the Context of Aging and Cancer Initiation
inferred← citeshttps://doi.org/10.1101/cshperspect.a037267openalex-snapshot
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inferred← citeshttps://doi.org/10.1101/cshperspect.a041330openalex-snapshot
Multidimensional Imaging of Breast Cancer
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Mutant p53 in cell-cell interactions
inferred← citeshttps://doi.org/10.1103/physreve.98.050401openalex-snapshot
Extreme value statistics of mutation accumulation in renewing cell populations
inferred← citeshttps://doi.org/10.1111/cas.15483openalex-snapshot
Basal extrusion of single‐oncogenic mutant cells induces dome‐like structures with altered microenvironments
inferred← citeshttps://doi.org/10.1111/exd.14305openalex-snapshot
Epigenetic and metabolic regulation of epidermal homeostasis
inferred← citeshttps://doi.org/10.1111/joim.13177openalex-snapshot
Cellular heterogeneity and microenvironmental control of skin cancer
inferred← citeshttps://doi.org/10.1111/nyas.14678openalex-snapshot
Metabolic decisions in development and disease—a Keystone Symposia report
inferred← citeshttps://doi.org/10.1126/science.adv8291openalex-snapshot
Chemically induced skin tumors arise from long-lived stem cells of the upper hair follicle
inferred← citeshttps://doi.org/10.1126/science.aed3065openalex-snapshot
Loss of the tumor suppressor p53 generates a signaling gradient that drives epithelial clonal expansion
inferred← citeshttps://doi.org/10.1134/s2079086419020075openalex-snapshot
Some Aspects of Carcinogenesis Associated with Genetic and Epigenetic Factors
inferred← citeshttps://doi.org/10.1158/0008-5472.can-17-2769openalex-snapshot
Genetic Mosaicism and Cancer: Cause and Effect
inferred← citeshttps://doi.org/10.1158/2159-8290.cd-24-1079openalex-snapshot
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inferred← citeshttps://doi.org/10.1158/2159-8290.cd-25-0779openalex-snapshot
Of Barriers and Loops—How Evolution Limits Most Cancer Risks to Older Ages
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An expanded view of cell competition
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Plasticity of differentiated cells in wound repair and tumorigenesis, part II: skin and intestine
inferred← citeshttps://doi.org/10.1242/dmm.052113openalex-snapshot
Nonlinear progression during the occult transition establishes cancer lethality
inferred← citeshttps://doi.org/10.1387/ijdb.170341fwopenalex-snapshot
Homeostasis, regeneration and tumour formation in the mammalian epidermis
inferred← citeshttps://doi.org/10.15252/embj.2021109675openalex-snapshot
3D imaging for driving cancer discovery
inferred← citeshttps://doi.org/10.15252/emmm.201910697openalex-snapshot
Role of bulge epidermal stem cells and TSLP signaling in psoriasis
inferred← citeshttps://doi.org/10.1530/erc-25-0242openalex-snapshot
Phaeochromocytomas and paragangliomas harbour tumour-initiating SOX2+ stem cells
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Cancer-associated fibroblasts of colorectal cancer and their markers: updates, challenges and translational outlook
inferred← citeshttps://doi.org/10.3389/fcell.2022.933370openalex-snapshot
Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1176594openalex-snapshot
Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1630658openalex-snapshot
Visualizing cellular interactions: intravital imaging in tumor microenvironment
inferred← citeshttps://doi.org/10.3389/fmed.2018.00165openalex-snapshot
Pathogenesis of Skin Carcinomas and a Stem Cell as Focal Origin
inferred← citeshttps://doi.org/10.3389/fonc.2018.00355openalex-snapshot
Multiple Myeloma Exemplifies a Model of Cancer Based on Tissue Disruption as the Initiator Event
inferred← citeshttps://doi.org/10.3389/fonc.2019.01408openalex-snapshot
Anakoinosis: Correcting Aberrant Homeostasis of Cancer Tissue—Going Beyond Apoptosis Induction
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Targeting Staphylococcus aureus dominated skin dysbiosis in actinic keratosis to prevent the onset of cutaneous squamous cell carcinoma: Outlook for future therapies?
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The role and mechanism of compressive stress in tumor
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Changes in Stem Cell Regulation and Epithelial Organisation during Carcinogenesis and Disease Progression in Gynaecological Malignancies
inferred← citeshttps://doi.org/10.3390/genes11080939openalex-snapshot
Wnt/β-catenin Signaling in Tissue Self-Organization
inferred← citeshttps://doi.org/10.3390/ijms19113540openalex-snapshot
Peroxisome Proliferator-Activated Receptors (PPAR)γ Agonists as Master Modulators of Tumor Tissue
inferred← citeshttps://doi.org/10.3390/ijms20030756openalex-snapshot
Abnormal Expression of c-Myc Oncogene in NK Cells in Patients with Cancer
inferred← citeshttps://doi.org/10.3390/ijms241713615openalex-snapshot
Lymph Vessels Associate with Cancer Stem Cells from Initiation to Malignant Stages of Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.3410/f.735763945.793569301openalex-snapshot
Faculty Opinions recommendation of Distinct modes of cell competition shape mammalian tissue morphogenesis.
inferred← citeshttps://doi.org/10.3934/mbe.2022625openalex-snapshot
Optimal treatment strategy of cancers with intratumor heterogeneity
inferred← citeshttps://doi.org/10.70675/c5a4265cz7577z45eeza66bz4aaa728ab681openalex-snapshot
Mechanisms of spontaneous loss of heterozygosity in adult stem cells
inferred← citeshttps://doi.org/10.7554/elife.46756openalex-snapshot
Coordinated hedgehog signaling induces new hair follicles in adult skin
inferred← citeshttps://doi.org/10.7554/elife.48482openalex-snapshot
Regulated spindle orientation buffers tissue growth in the epidermis
inferred← citeshttps://doi.org/10.7554/elife.54618openalex-snapshot
Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
inferred← citeshttps://doi.org/10.7554/elife.60541openalex-snapshot
MAPK activity dynamics regulate non-cell autonomous effects of oncogene expression
inferred← citeshttps://doi.org/10.7554/elife.74912openalex-snapshot
When oncogenes do not cause cancer
inferred← citeshttps://doi.org/10.7554/elife.78837openalex-snapshot
Live-cell imaging in human colonic monolayers reveals ERK waves limit the stem cell compartment to maintain epithelial homeostasis
inferred← citeshttps://doi.org/10.7554/elife.97650openalex-snapshot
In vivo targeted and deterministic single-cell malignant transformation
inferred← citeshttps://doi.org/10.7554/elife.97650.1openalex-snapshot
In vivo targeted and deterministic single cell malignant transformation
inferred← citeshttps://doi.org/10.7554/elife.97650.2openalex-snapshot
In vivo targeted and deterministic single cell malignant transformation
inferred← citeshttps://doi.org/10.7554/elife.97650.3openalex-snapshot
In vivo targeted and deterministic single-cell malignant transformation
inferred← citeshttps://doi.org/10.7868/s0042132418050010openalex-snapshot
НЕКОТОРЫЕ АСПЕКТЫ КАНЦЕРОГЕНЕЗА, СВЯЗАННЫЕ С ГЕНЕТИЧЕСКИМИ И ЭПИГЕНЕТИЧЕСКИМИ ФАКТОРАМИ, "Успехи современной биологии"
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