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MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

https://doi.org/10.1038/ncb2741
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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pWormgatePro enables promoter-driven knockdown by hairpin RNA interference of muscle and neuronal gene products in Caenorhabditis elegans
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A Multiparameter Network Reveals Extensive Divergence between C. elegans bHLH Transcription Factors
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IRE-1 and HSP-4 Contribute to Energy Homeostasis via Fasting-Induced Lipases in C. elegans
inferredcites →https://doi.org/10.1016/j.cmet.2009.10.002openalex-snapshot
C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles
inferredcites →https://doi.org/10.1016/j.cmet.2011.06.019openalex-snapshot
Insulin/IGF-1 Receptor Signaling Enhances Biosynthetic Activity and Fat Mobilization in the Initial Phase of Starvation in Adult Male C. elegans
inferredcites →https://doi.org/10.1016/s0960-9822(02)00928-4openalex-snapshot
Inducible Antibacterial Defense System in C. elegans
inferredcites →https://doi.org/10.1038/emboj.2012.32openalex-snapshot
A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
inferredcites →https://doi.org/10.1038/nature01279openalex-snapshot
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
inferredcites →https://doi.org/10.1038/nature07536openalex-snapshot
Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
inferredcites →https://doi.org/10.1038/nature07976openalex-snapshot
Autophagy regulates lipid metabolism
inferredcites →https://doi.org/10.1038/nprot.2008.38openalex-snapshot
Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans
inferredcites →https://doi.org/10.1073/pnas.0506234102openalex-snapshot
A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49
inferredcites →https://doi.org/10.1073/pnas.092064799openalex-snapshot
Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans
inferredcites →https://doi.org/10.1091/mbc.e06-08-0685openalex-snapshot
Function of the Caenorhabditis elegans ABC Transporter PGP-2 in the Biogenesis of a Lysosome-related Fat Storage Organelle
inferredcites →https://doi.org/10.1093/bioinformatics/bti650openalex-snapshot
TARGET: a new method for predicting protein subcellular localization in eukaryotes
inferredcites →https://doi.org/10.1093/emboj/cdf600openalex-snapshot
Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar‐dependent response
inferredcites →https://doi.org/10.1093/nar/29.9.e45openalex-snapshot
A new mathematical model for relative quantification in real-time RT-PCR
inferredcites →https://doi.org/10.1093/nar/gkl093openalex-snapshot
pTARGET: a web server for predicting protein subcellular localization
inferredcites →https://doi.org/10.1101/gad.1588907openalex-snapshot
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants
inferredcites →https://doi.org/10.1101/gad.1901210openalex-snapshot
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
inferredcites →https://doi.org/10.1101/gr.2445504openalex-snapshot
A Gateway-Compatible Yeast One-Hybrid System
inferredcites →https://doi.org/10.1126/science.1087782openalex-snapshot
Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans
inferredcites →https://doi.org/10.1126/science.1174447openalex-snapshot
A Gene Network Regulating Lysosomal Biogenesis and Function
inferredcites →https://doi.org/10.1126/science.1204592openalex-snapshot
TFEB Links Autophagy to Lysosomal Biogenesis
inferredcites →https://doi.org/10.1126/science.1220281openalex-snapshot
LAAT-1 Is the Lysosomal Lysine/Arginine Transporter That Maintains Amino Acid Homeostasis
inferredcites →https://doi.org/10.1126/scisignal.2002790openalex-snapshot
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
inferredcites →https://doi.org/10.1146/annurev-genet-102808-114910openalex-snapshot
Regulation Mechanisms and Signaling Pathways of Autophagy
inferredcites →https://doi.org/10.1152/ajpendo.00562.2009openalex-snapshot
Potential role of autophagy in modulation of lipid metabolism
inferredcites →https://doi.org/10.1152/ajplegacy.1909.24.2.294openalex-snapshot
A NOTE ON THE ABSORPTION OF FAT
inferredcites →https://doi.org/10.1152/physiolgenomics.00203.2003openalex-snapshot
Starvation response in mouse liver shows strong correlation with life-span-prolonging processes
inferredcites →https://doi.org/10.1242/dev.00363openalex-snapshot
Global analysis of dauer gene expression inCaenorhabditis elegans
inferredcites →https://doi.org/10.1371/journal.pgen.0040024openalex-snapshot
A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans
inferredcites →https://doi.org/10.4161/auto.9040openalex-snapshot
Lipases in lysosomes, what for?

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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A Sphingolipid-mTORC1 Nutrient-Sensing Machinery Enables Animal Development by Suppression of the Intestinal Peroxisome Relocation, Hormone Secretion and the Gut-Brain Crosstalk
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C. elegans ACAT regulates lipolysis and its related lifespan in fasting through modulation of the genes in lipolysis and insulin/ IGF ‐1 signaling
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Lysosomes Mediate Benefits of Intermittent Fasting in Cardiometabolic Disease: The Janitor Is the Undercover Boss
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Genome‐wide screen identifies signaling pathways that regulate autophagy during Caenorhabditis elegans development
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A Multiplex Gene Expression Assay for Direct Measurement of RNA Transcripts in Crude Lysates of the Nematode Caenorhabditis elegans Used as a Bioanalytical Tool
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Suppression of Autophagy During Liver Regeneration Impairs Energy Charge and Hepatocyte Senescence in Mice
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Lysosomes Mediate Benefits of Intermittent Fasting in Cardiometabolic Disease: The Janitor Is the Undercover Boss
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Lipophagy in nonliver tissues and some related diseases: Pathogenic and therapeutic implications
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Relative transcription of autophagy-related genes in Amblyomma sculptum and Rhipicephalus microplus ticks
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C. elegans to model autophagy-related human disorders
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Irisin-mediated hepatic autophagy remodels nutritional metabolism to prevent cognitive dysfunction
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FoxO1 at the nexus between fat catabolism and longevity pathways
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Lipid droplets, lipophagy, and beyond
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Lipase-like 5 enzyme controls mitochondrial activity in response to starvation in Caenorhabditis elegans
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Managing lipid metabolism in proliferating cells: New perspective for metformin usage in cancer therapy
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Impacts of a high-glucose diet or starvation on microRNA-transcription factor networks in Caenorhabditis elegans through Boolean mathematical modeling
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Fatty Acids Regulate Germline Sex Determination through ACS-4-Dependent Myristoylation
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Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan
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Coelomocytes Regulate Starvation-Induced Fat Catabolism and Lifespan Extension through the Lipase LIPL-5 in Caenorhabditis elegans
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A sphingolipid-mTORC1 nutrient-sensing pathway regulates animal development by an intestinal peroxisome relocation-based gut-brain crosstalk
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Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans
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An ECM-to-Nucleus Signaling Pathway Activates Lysosomes for C. elegans Larval Development
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HLH-30/TFEB Is a Master Regulator of Reproductive Quiescence
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Lipid metabolism and lipid signals in aging and longevity
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Ferulic acid delayed amyloid β-induced pathological symptoms by autophagy pathway via a fasting-like effect in Caenorhabditis elegans
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Innate Host Defense Requires TFEB-Mediated Transcription of Cytoprotective and Antimicrobial Genes
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Cell non-autonomous control of autophagy and metabolism by glial cells
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Bile Acids: The Hidden Gateway Behind Autophagy Modulation in the Liver
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Critical Role of TFEB-Mediated Lysosomal Biogenesis in Alcohol-Induced Pancreatitis in Mice and Humans
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Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics
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Metformin-induced TTP mediates communication between Kupffer cells and hepatocytes to alleviate hepatic steatosis by regulating lipophagy and necroptosis
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Caffeine extends lifespan by enhancing lysosomal lipolysis in Caenorhabditis elegans
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The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity
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Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A
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Lysosome: regulator of lipid degradation pathways
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Emerging Roles for the Lysosome in Lipid Metabolism
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Lysosomes: Signaling Hubs for Metabolic Sensing and Longevity
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Caenorhabditis elegans metabolic gene regulatory networks govern the cellular economy
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Investigating Connections between Metabolism, Longevity, and Behavior in Caenorhabditis elegans
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Lipophagy: a new player in CNS disorders
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Lipophagy and lipid droplets in neurodegeneration
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High- and low-throughput scoring of fat mass and body fat distribution in C. elegans
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Tools and methods to analyze autophagy in C. elegans
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Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate Enhances foxo1-Mediated Lipophagy to Remodel Lipid Metabolism in Zebrafish Liver
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FoxO1 controls lysosomal acid lipase in adipocytes: implication of lipophagy during nutrient restriction and metformin treatment
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You are what you eat: multifaceted functions of autophagy during C. elegans development
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Preventing lysosomal fat indigestion
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Erratum: Corrigendum: MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
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Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
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Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans
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Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
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The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans
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SKN-1 and Nrf2 couples proline catabolism with lipid metabolism during nutrient deprivation
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The role of protein clearance mechanisms in organismal ageing and age-related diseases
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Protein Kinase C β: a New Target Therapy to Prevent the Long-Term Atypical Antipsychotic-Induced Weight Gain
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Liver autophagy: much more than just taking out the trash
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Autophagy in the liver: functions in health and disease
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Cytosolic lipolysis and lipophagy: two sides of the same coin
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Signals from the lysosome: a control centre for cellular clearance and energy metabolism
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Autophagy at the crossroads of catabolism and anabolism
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Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation
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Past, present, and future perspectives of transcription factor EB (TFEB): mechanisms of regulation and association with disease
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The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders
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DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
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HLH-11 modulates lipid metabolism in response to nutrient availability
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Glycerol 3-phosphate phosphatase/PGPH-2 counters metabolic stress and promotes healthy aging via a glycogen sensing-AMPK-HLH-30-autophagy axis in C. elegans
inferred← citeshttps://doi.org/10.1038/s41467-024-44978-wopenalex-snapshot
ATG14 targets lipid droplets and acts as an autophagic receptor for syntaxin18-regulated lipid droplet turnover
inferred← citeshttps://doi.org/10.1038/s41467-025-55950-7openalex-snapshot
Modulation by NPY/NPF-like receptor underlies experience-dependent, sexually dimorphic learning
inferred← citeshttps://doi.org/10.1038/s41467-025-64341-xopenalex-snapshot
Different gametogenesis states uniquely impact longevity in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1038/s41556-018-0244-7openalex-snapshot
The lysosome as a cellular centre for signalling, metabolism and quality control
inferred← citeshttps://doi.org/10.1038/s41556-025-01693-yopenalex-snapshot
A lysosomal surveillance response to stress extends healthspan
inferred← citeshttps://doi.org/10.1038/s41577-025-01167-0openalex-snapshot
Patterns of pathogenesis in innate immunity: insights from C. elegans
inferred← citeshttps://doi.org/10.1038/s41580-018-0033-yopenalex-snapshot
Autophagy as a promoter of longevity: insights from model organisms
inferred← citeshttps://doi.org/10.1038/s41580-023-00641-8openalex-snapshot
The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease
inferred← citeshttps://doi.org/10.1038/s41580-023-00676-xopenalex-snapshot
Lysosomes as coordinators of cellular catabolism, metabolic signalling and organ physiology
inferred← citeshttps://doi.org/10.1038/s41589-020-0565-2openalex-snapshot
Spectroscopic coherent Raman imaging of Caenorhabditis elegans reveals lipid particle diversity
inferred← citeshttps://doi.org/10.1038/s41598-017-05276-2openalex-snapshot
Differential adiponectin signalling couples ER stress with lipid metabolism to modulate ageing in C. elegans
inferred← citeshttps://doi.org/10.1038/s41598-022-11325-2openalex-snapshot
Remofuscin induces xenobiotic detoxification via a lysosome-to-nucleus signaling pathway to extend the Caenorhabditis elegans lifespan
inferred← citeshttps://doi.org/10.1038/s42255-024-01003-0openalex-snapshot
Futile lipid cycling: from biochemistry to physiology
inferred← citeshttps://doi.org/10.1038/s43587-022-00329-2openalex-snapshot
piRNAs regulate a Hedgehog germline-to-soma pro-aging signal
inferred← citeshttps://doi.org/10.1038/s43587-023-00524-9openalex-snapshot
A drug-like molecule engages nuclear hormone receptor DAF-12/FXR to regulate mitophagy and extend lifespan
inferred← citeshttps://doi.org/10.1038/srep02777openalex-snapshot
Density dependence in Caenorhabditis larval starvation
inferred← citeshttps://doi.org/10.1038/srep43547openalex-snapshot
Antioxidant response is a protective mechanism against nutrient deprivation in C. elegans
inferred← citeshttps://doi.org/10.1039/c9en00473dopenalex-snapshot
Neuronal damage induced by nanopolystyrene particles in nematode Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1042/bj20140191openalex-snapshot
PKG and NHR-49 signalling co-ordinately regulate short-term fasting-induced lysosomal lipid accumulation in C. elegans
inferred← citeshttps://doi.org/10.1053/j.gastro.2015.09.042openalex-snapshot
Regulation of Liver Metabolism by Autophagy
inferred← citeshttps://doi.org/10.1073/pnas.2011379118openalex-snapshot
The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics
inferred← citeshttps://doi.org/10.1073/pnas.2101410118openalex-snapshot
Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling
inferred← citeshttps://doi.org/10.1073/pnas.2104832118openalex-snapshot
Context-specific regulation of lysosomal lipolysis through network-level diverting of transcription factor interactions
inferred← citeshttps://doi.org/10.1073/pnas.2403906121openalex-snapshot
The neurotrophic factor MANF regulates autophagy and lysosome function to promote proteostasis in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1080/15548627.2014.1003478openalex-snapshot
Guidelines for monitoring autophagy in Caenorhabditis elegans.
inferred← citeshttps://doi.org/10.1080/15548627.2015.1034410openalex-snapshot
Transcriptional and epigenetic regulation of autophagy in aging
inferred← citeshttps://doi.org/10.1080/15548627.2015.1100356openalex-snapshot
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
inferred← citeshttps://doi.org/10.1080/15548627.2015.1127464openalex-snapshot
Autophagy-mediated longevity is modulated by lipoprotein biogenesis
inferred← citeshttps://doi.org/10.1080/15548627.2015.1134080openalex-snapshot
Control of lysosomal biogenesis and Notch-dependent tissue patterning by components of the TFEB-V-ATPase axis inDrosophila melanogaster
inferred← citeshttps://doi.org/10.1080/15548627.2015.1134081openalex-snapshot
DrosophilaMitf regulates the V-ATPase and the lysosomal-autophagic pathway
inferred← citeshttps://doi.org/10.1080/15548627.2015.1136771openalex-snapshot
Autophagy and modular restructuring of metabolism control germline tumor differentiation and proliferation inC. elegans
inferred← citeshttps://doi.org/10.1080/15548627.2016.1147671openalex-snapshot
A lysosome-centered view of nutrient homeostasis
inferred← citeshttps://doi.org/10.1080/15548627.2016.1256933openalex-snapshot
HLH-30/TFEB-mediated autophagy functions in a cell-autonomous manner for epithelium intrinsic cellular defense against bacterial pore-forming toxin inC. elegans
inferred← citeshttps://doi.org/10.1080/15548627.2017.1313943openalex-snapshot
Emerging roles for TFEB in the immune response and inflammation
inferred← citeshttps://doi.org/10.1080/15548627.2020.1728097openalex-snapshot
Lipophagy-derived fatty acids undergo extracellular efflux via lysosomal exocytosis
inferred← citeshttps://doi.org/10.1080/15548627.2020.1797280openalex-snapshot
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
inferred← citeshttps://doi.org/10.1080/15548627.2022.2068267openalex-snapshot
SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity
inferred← citeshttps://doi.org/10.1080/15548627.2022.2105561openalex-snapshot
Regulation of TFEB nuclear localization by HSP90AA1 promotes autophagy and longevity
inferred← citeshttps://doi.org/10.1080/15548627.2025.2482724openalex-snapshot
T16G12.6/IMPORTIN 13-mediated cytoplasm-to-nucleus transport of the THAP transcription factor LIN-15B controls autophagy and lysosome function in C. elegans
inferred← citeshttps://doi.org/10.1080/21541264.2016.1264353openalex-snapshot
TFEB and TFE3: The art of multi-tasking under stress conditions
inferred← citeshttps://doi.org/10.1080/21655979.2022.2065761openalex-snapshot
High expression of H2A histone family member Y promotes the proliferation and autophagy of hepatocellular carcinoma cells
inferred← citeshttps://doi.org/10.1080/27694127.2023.2277584openalex-snapshot
MALT-1 shortens lifespan by inhibiting autophagy in the intestine of C. elegans
inferred← citeshttps://doi.org/10.1083/jcb.201307084openalex-snapshot
Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases
inferred← citeshttps://doi.org/10.1083/jcb.201607005openalex-snapshot
The lysosome as a command-and-control center for cellular metabolism
inferred← citeshttps://doi.org/10.1083/jcb.201907067openalex-snapshot
Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30
inferred← citeshttps://doi.org/10.1083/jcb.202102001openalex-snapshot
Lysosome biogenesis: Regulation and functions
inferred← citeshttps://doi.org/10.1083/jcb.202402016openalex-snapshot
LYSMD proteins promote activation of Rab32-family GTPases for lysosome-related organelle biogenesis
inferred← citeshttps://doi.org/10.1091/mbc.e13-09-0521openalex-snapshot
Caenorhabditis elegansHOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1
inferred← citeshttps://doi.org/10.1093/genetics/iyaf007openalex-snapshot
Conserved components of the macroautophagy machinery in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1093/genetics/iyaf016openalex-snapshot
Activated SKN-1 alters the aging trajectories of long-lived Caenorhabditis elegans mutants
inferred← citeshttps://doi.org/10.1093/genetics/iyag044openalex-snapshot
The TWK-26/KCNK3 potassium channel and FLR-4 protein kinase coordinate nutrient absorption in the C. elegans intestine
inferred← citeshttps://doi.org/10.1093/jleuko/qiaf077openalex-snapshot
TFEB-mediated proinflammatory response in murine macrophages induced by acute Alpha7 nicotinic receptor activation
inferred← citeshttps://doi.org/10.1093/nar/gkag949openalex-snapshot
HLH-30/TFEB is necessary for chromatin reorganization and maintenance of cell quiescence during starvation in C. elegans
inferred← citeshttps://doi.org/10.1093/procel/pwac063openalex-snapshot
ORP8 acts as a lipophagy receptor to mediate lipid droplet turnover
inferred← citeshttps://doi.org/10.1096/fj.201901880ropenalex-snapshot
Lifespan‐extending interventions enhance lipid‐supported mitochondrial respiration in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1097/mol.0000000000000273openalex-snapshot
AMP-activated protein kinase and its multifaceted regulation of hepatic metabolism
inferred← citeshttps://doi.org/10.1101/156109openalex-snapshot
Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1101/2019.12.20.882514openalex-snapshot
A neuronal thermostat controls membrane fluidity in C. elegans
inferred← citeshttps://doi.org/10.1101/2020.08.31.276006openalex-snapshot
A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage
inferred← citeshttps://doi.org/10.1101/2021.01.21.427623openalex-snapshot
miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to affect muscle contractility upon proteotoxic challenge during ageing
inferred← citeshttps://doi.org/10.1101/2021.05.15.444169openalex-snapshot
A lipid-mTORC1 nutrient sensing pathway regulates animal development by peroxisome-derived hormones
inferred← citeshttps://doi.org/10.1101/2022.01.28.478261openalex-snapshot
Transcriptome Analysis of the Nematode Caenorhabditis elegans and Litoditis marina in a Chemically Defined Food Environment
inferred← citeshttps://doi.org/10.1101/2022.04.07.487519openalex-snapshot
Neuronal HLH-30/TFEB modulates muscle mitochondrial fragmentation to improve thermoresistance in C. elegans
inferred← citeshttps://doi.org/10.1101/2022.09.12.507697openalex-snapshot
Negative regulation of C. elegans innate immunity by orphan nuclear receptor NHR-42
inferred← citeshttps://doi.org/10.1101/2023.01.13.523898openalex-snapshot
IL-17 undermines longevity and stress tolerance by inhibiting a protective transcriptional network
inferred← citeshttps://doi.org/10.1101/2023.07.31.551399openalex-snapshot
Neurotrophic factor MANF regulates autophagy and lysosome function to promote proteostasis in C. elegans
inferred← citeshttps://doi.org/10.1101/2023.10.19.563073openalex-snapshot
Modulation by NPYR underlies experience-dependent, sexually dimorphic learning
inferred← citeshttps://doi.org/10.1101/2023.12.07.570559openalex-snapshot
Lithocholic acid phenocopies rejuvenating and life-extending effects of calorie restriction
inferred← citeshttps://doi.org/10.1101/2024.04.11.588856openalex-snapshot
An intestinal Sir2-HSF1-ATGL1 pathway regulates lipolysis in C. elegans
inferred← citeshttps://doi.org/10.1101/2024.04.11.589121openalex-snapshot
Mechanical stress through growth on stiffer substrates impacts animal health and longevity in C. elegans
inferred← citeshttps://doi.org/10.1101/2024.07.09.602737openalex-snapshot
Activated SKN-1 alters the aging trajectories of long-lived C. elegans mutants
inferred← citeshttps://doi.org/10.1101/2024.11.29.625995openalex-snapshot
TFEB/HLH-30-mediated expansion of neuronal lysosomal capacity in early adulthood protects dendrite maintenance during aging in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1101/2025.06.28.662086openalex-snapshot
Microbial Tryptophan Metabolism Activates Host Lysosomal Activity to Facilitate Lipid Breakdown and Ameliorate Hepatic Steatosis
inferred← citeshttps://doi.org/10.1101/2025.10.03.680215openalex-snapshot
RiboTRAP-seq identifies spatially distinct functions for the anterior and posterior intestine in immune and metabolic regulation in C. elegans
inferred← citeshttps://doi.org/10.1101/549907openalex-snapshot
Nuclear hormone receptor NHR-49 shapes immuno-metabolic response of Caenorhabditis elegans to Enterococcus faecalis infection
inferred← citeshttps://doi.org/10.1101/609610openalex-snapshot
Caenorhabditis elegans sensory neurons modulate pathogen specific responses via HLH-30/TFEB transcription factor and FSHR-1 GPCR axes of immunity
inferred← citeshttps://doi.org/10.1101/723312openalex-snapshot
Nutrient-dependent mTORC1 signaling in coral-algal symbiosis
inferred← citeshttps://doi.org/10.1101/cshperspect.a016907openalex-snapshot
Lysosomal Adaptation: How the Lysosome Responds to External Cues
inferred← citeshttps://doi.org/10.1111/acel.12689openalex-snapshot
TOR ‐mediated regulation of metabolism in aging
inferred← citeshttps://doi.org/10.1111/acel.12743openalex-snapshot
NHR ‐49/ HNF 4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting
inferred← citeshttps://doi.org/10.1111/acel.13342openalex-snapshot
HLH‐30‐dependent rewiring of metabolism during starvation in C . elegans
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