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Elimination of HIV-1-infected cells by broadly neutralizing antibodies

https://doi.org/10.1038/ncomms10844
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.cell.2013.09.044openalex-snapshot
An Integrated Overview of HIV-1 Latency
inferredcites →https://doi.org/10.1016/j.cell.2014.07.043openalex-snapshot
Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice
inferredcites →https://doi.org/10.1016/j.cell.2014.08.023openalex-snapshot
Broadly Neutralizing Anti-HIV-1 Antibodies Require Fc Effector Functions for In Vivo Activity
inferredcites →https://doi.org/10.1016/j.cell.2015.01.020openalex-snapshot
HIV-1 Integration Landscape during Latent and Active Infection
inferredcites →https://doi.org/10.1016/j.cell.2015.10.027openalex-snapshot
Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology
inferredcites →https://doi.org/10.1016/j.chom.2015.03.002openalex-snapshot
Passively Acquired Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity in HIV-Infected Infants Is Associated with Reduced Mortality
inferredcites →https://doi.org/10.1016/j.immuni.2012.01.014openalex-snapshot
Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation
inferredcites →https://doi.org/10.1016/j.it.2014.08.007openalex-snapshot
Antibody B cell responses in HIV-1 infection
inferredcites →https://doi.org/10.1016/j.tim.2015.01.013openalex-snapshot
Towards an HIV-1 cure: measuring the latent reservoir
inferredcites →https://doi.org/10.1038/nature06106openalex-snapshot
Fc receptor but not complement binding is important in antibody protection against HIV
inferredcites →https://doi.org/10.1038/nature13612openalex-snapshot
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
inferredcites →https://doi.org/10.1038/nature14411openalex-snapshot
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
inferredcites →https://doi.org/10.1038/ncomms9447openalex-snapshot
Activation and lysis of human CD4 cells latently infected with HIV-1
inferredcites →https://doi.org/10.1038/ni.3158openalex-snapshot
Antibody responses to envelope glycoproteins in HIV-1 infection
inferredcites →https://doi.org/10.1038/nm.1949openalex-snapshot
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
inferredcites →https://doi.org/10.1038/nm.1972openalex-snapshot
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
inferredcites →https://doi.org/10.1038/nri3262openalex-snapshot
Towards an HIV cure: a global scientific strategy
inferredcites →https://doi.org/10.1056/nejmoa1113425openalex-snapshot
Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial
inferredcites →https://doi.org/10.1073/pnas.1016048108openalex-snapshot
Immune escape from HIV-specific antibody-dependent cellular cytotoxicity (ADCC) pressure
inferredcites →https://doi.org/10.1073/pnas.1217207109openalex-snapshot
Complex-type N -glycan recognition by potent broadly neutralizing HIV antibodies
inferredcites →https://doi.org/10.1073/pnas.1321507111openalex-snapshot
Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity
inferredcites →https://doi.org/10.1073/pnas.1414148111openalex-snapshot
Broadly neutralizing antibodies suppress HIV in the persistent viral reservoir
inferredcites →https://doi.org/10.1073/pnas.1506755112openalex-snapshot
CD4 mimetics sensitize HIV-1-infected cells to ADCC
inferredcites →https://doi.org/10.1084/jem.20090378openalex-snapshot
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
inferredcites →https://doi.org/10.1084/jem.20121827openalex-snapshot
Neutralizing antibodies to HIV-1 induced by immunization
inferredcites →https://doi.org/10.1084/jem.20131244openalex-snapshot
Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission
inferredcites →https://doi.org/10.1089/aid.2014.0235openalex-snapshot
Exploring the Potential of Monoclonal Antibody Therapeutics for HIV-1 Eradication
inferredcites →https://doi.org/10.1097/01.qai.0000479721.09749.2dopenalex-snapshot
B-108 Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
inferredcites →https://doi.org/10.1097/qad.0000000000000523openalex-snapshot
The role of HIV-specific antibody-dependent cellular cytotoxicity in HIV prevention and the influence of the HIV-1 Vpu protein
inferredcites →https://doi.org/10.1097/qad.0b013e328329f97dopenalex-snapshot
Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers
inferredcites →https://doi.org/10.1126/science.1207227openalex-snapshot
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
inferredcites →https://doi.org/10.1126/science.1241144openalex-snapshot
Antibodies in HIV-1 Vaccine Development and Therapy
inferredcites →https://doi.org/10.1126/science.1254194openalex-snapshot
Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
inferredcites →https://doi.org/10.1126/science.aab3886openalex-snapshot
Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys
inferredcites →https://doi.org/10.1126/science.aac4223openalex-snapshot
HIV-1 neutralizing antibodies induced by native-like envelope trimers
inferredcites →https://doi.org/10.1128/jvi.00287-12openalex-snapshot
Antibody-Dependent Cellular Cytotoxicity against Primary HIV-Infected CD4+T Cells Is Directly Associated with the Magnitude of Surface IgG Binding
inferredcites →https://doi.org/10.1128/jvi.00449-14openalex-snapshot
HIV-1 Vpu Antagonism of Tetherin Inhibits Antibody-Dependent Cellular Cytotoxic Responses by Natural Killer Cells
inferredcites →https://doi.org/10.1128/jvi.02108-09openalex-snapshot
Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
inferredcites →https://doi.org/10.1128/jvi.02717-15openalex-snapshot
Antibody-Dependent Cellular Cytotoxicity against Reactivated HIV-1-Infected Cells
inferredcites →https://doi.org/10.1128/jvi.03136-14openalex-snapshot
Improving Neutralization Potency and Breadth by Combining Broadly Reactive HIV-1 Antibodies Targeting Major Neutralization Epitopes
inferredcites →https://doi.org/10.1128/jvi.06157-11openalex-snapshot
Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of Their Replication Capacity in CD4 T Lymphocytes and Monocyte-Derived Macrophages
inferredcites →https://doi.org/10.1128/jvi.79.15.9625-9634.2005openalex-snapshot
Evidence that Low-Level Viremias during Effective Highly Active Antiretroviral Therapy Result from Two Processes: Expression of Archival Virus and Replication of Virus
inferredcites →https://doi.org/10.1186/1742-4690-11-15openalex-snapshot
HIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2
inferredcites →https://doi.org/10.1371/journal.pone.0024078openalex-snapshot
Memory B Cell Antibodies to HIV-1 gp140 Cloned from Individuals Infected with Clade A and B Viruses
inferredcites →https://doi.org/10.1371/journal.ppat.1000955openalex-snapshot
Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission
inferredcites →https://doi.org/10.1371/journal.ppat.1004966openalex-snapshot
Capacity of Broadly Neutralizing Antibodies to Inhibit HIV-1 Cell-Cell Transmission Is Strain- and Epitope-Dependent
inferredcites →https://doi.org/10.3389/fimmu.2015.00265openalex-snapshot
Can HIV-1-Specific ADCC Assist the Clearance of Reactivated Latently Infected Cells?

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Structural Basis for Broad HIV-1 Neutralization by a Novel MPER-Specific Human Broadly Neutralizing Antibody
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Estrogen Modulation of B Cell Immunity: Implications for HIV Control and Therapeutic Strategies
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γδ T cells mediate robust anti‐HIV functions during antiretroviral therapy regardless of immune checkpoint expression
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Identification of the predominant human NK cell effector subset mediating ADCC against HIV‐infected targets coated with BNAbs or plasma from PLWH
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Adaptive NK cell responses in HIV/SIV infections: A roadmap to cell-based therapeutics?
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Peering into the HIV reservoir
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Techniques for Developing and Assessing Immune Responses Induced by Synthetic DNA Vaccines for Emerging Infectious Diseases
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Broadly Neutralizing Antibodies as Treatment: Effects on Virus and Immune System
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Breaking the Glyco-Code of HIV Persistence and Immunopathogenesis
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Viral and Host Biomarkers of HIV Remission Post Treatment Interruption
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More than the Infinite Monkey Theorem: NHP Models in the Development of a Pediatric HIV Cure
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Strategies for HIV-1 elimination
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Next-generation bNAbs for HIV-1 cure strategies
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Functional comparison of Fc-engineering strategies to improve anti-HIV-1 antibody effector functions
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The role of conventional antibodies targeting the CD4 binding site and CD4-induced epitopes in the control of HIV-1 CRF01_AE viruses
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Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform
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Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.03.032openalex-snapshot
HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.108502openalex-snapshot
HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound
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Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111983openalex-snapshot
Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115331openalex-snapshot
Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope
inferred← citeshttps://doi.org/10.1016/j.chom.2019.05.009openalex-snapshot
HIV-1 Envelope FRETted Over by Antibodies
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Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01
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Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller
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HIV in Neonates and Infants
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Hunting Down the HIV-1 Reservoir: A Starring Role for Antibodies?
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Comprehensive analysis of neutrophil immunomodulatory properties and FcR dynamics in HIV-1 infection and therapy
inferred← citeshttps://doi.org/10.1016/j.it.2017.12.006openalex-snapshot
HIV Reactivation after Partial Protection by Neutralizing Antibodies
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Decoding the glycan shield: Immune recognition and response to the HIV-1 envelope trimer
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Modeling HIV dynamics under broadly neutralizing antibodies: The potential role of cell-to-cell virus transmission
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Adeno-associated virus-vectored delivery of HIV biologics: the promise of a “single-shot” functional cure for HIV infection
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Broadly neutralising antibodies in HIV: from clinical promise to therapeutic reality—a narrative review
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Targeting HIV-1 immune escape mechanisms: Key advances and challenges in HIV-1 vaccine design
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Engineered Antigen-Specific T Cells Secreting Broadly Neutralizing Antibodies: Combining Innate and Adaptive Immune Response against HIV
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HIV Entry and Its Inhibition by Bifunctional Antiviral Proteins
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Genetic Strategies for HIV Treatment and Prevention
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RNA-encoded PGT121-LS anti-HIV antibody: Comprehensive preclinical characterization and translational pharmacokinetics
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H3BERTa: A CDR-H3-specific language model for antibody repertoire analysis
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Immunological approaches to HIV cure
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Collective Infectious Units in Viruses
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Impact of HIV-1 Envelope Conformation on ADCC Responses
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The Conformational States of the HIV-1 Envelope Glycoproteins
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Immunological profiles of HIV-positive recipients of liver transplant
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Selective reactivation of latent HIV using CyclinT1-Tat-containing virus-like particles
inferred← citeshttps://doi.org/10.1016/j.virusres.2021.198470openalex-snapshot
Identification of a CD4-binding site-directed antibody with ADCC activity from a chronic HIV-1B′-infected Chinese donor
inferred← citeshttps://doi.org/10.1016/j.xcrm.2021.100275openalex-snapshot
Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies
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Long-Term Persistence of Anti-HIV Broadly Neutralizing Antibody-Secreting Hematopoietic Cells in Humanized Mice
inferred← citeshttps://doi.org/10.1016/s0140-6736(21)00570-5openalex-snapshot
Eliminating postnatal HIV transmission in high incidence areas: need for complementary biomedical interventions
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Barriers and strategies to achieve a cure for HIV
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Preventive and therapeutic features of broadly neutralising monoclonal antibodies against HIV-1
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Proof-of-Concept Development and Preclinical Evaluation of a Microarray Patch Platform for Codelivery of Multiple Broadly Neutralizing Antibodies for HIV Prevention
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Harnessing Antibody-Dependent Cellular Cytotoxicity To Control HIV-1 Infection
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Identification of Novel Neutralizing Monoclonal Antibodies against SARS-CoV-2 Spike Glycoprotein
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Combination treatment prevents HIV re-emergence in monkeys
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An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene
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HIV-1 Env DNA prime plus gp120 and gp70-V1V2 boosts induce high level of V1V2-specific IgG and ADCC responses and low level of Env-specific IgA response: implication for improving RV144 vaccine regimen
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Broadly neutralizing antibodies suppress post-transcytosis HIV-1 infectivity
inferred← citeshttps://doi.org/10.1038/nature21710openalex-snapshot
CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
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Beyond binding: antibody effector functions in infectious diseases
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A potent and broad CD4 binding site neutralizing antibody with strong ADCC activity from a Chinese HIV-1 elite neutralizer
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HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA)
inferred← citeshttps://doi.org/10.1038/s41467-022-28307-7openalex-snapshot
Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells
inferred← citeshttps://doi.org/10.1038/s41467-022-29511-1openalex-snapshot
Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers
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Mucosal application of the broadly neutralizing antibody 10-1074 protects macaques from cell-associated SHIV vaginal exposure
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High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials
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Engaging innate immunity in HIV-1 cure strategies
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Sustained HIV-1 remission after heterozygous CCR5Δ32 stem cell transplantation
inferred← citeshttps://doi.org/10.1038/s41590-020-0593-9openalex-snapshot
HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells
inferred← citeshttps://doi.org/10.1038/s41590-023-01741-5openalex-snapshot
Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells
inferred← citeshttps://doi.org/10.1038/s41590-026-02448-zopenalex-snapshot
Autologous neutralizing antibodies and polyfunctional T cells contribute to long-term HIV-1 post-intervention control
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AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques
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Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells
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Autologous and broadly neutralizing antibodies drive ART-free HIV control
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Development of an antibody-dependent cellular cytotoxicity reporter assay for measuring anti-Middle East Respiratory Syndrome antibody bioactivity
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Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies
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Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through cell-mediated killing
inferred← citeshttps://doi.org/10.1038/s44222-025-00387-2openalex-snapshot
mRNA technology for the prevention and treatment of HIV-1 infection
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CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge
inferred← citeshttps://doi.org/10.1038/srep37225openalex-snapshot
Enhancing Virion Tethering by BST2 Sensitizes Productively and Latently HIV-infected T cells to ADCC Mediated by Broadly Neutralizing Antibodies
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Naturally Occurring Fc-Dependent Antibody From HIV-Seronegative Individuals Promotes HIV-Induced IFN-α Production
inferred← citeshttps://doi.org/10.1051/medsci/20163208004openalex-snapshot
Des anticorps qui détruisent les cellules infectées par le VIH-1
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Dysregulated Response of Follicular Helper T Cells to Hepatitis B Surface Antigen Promotes HBV Persistence in Mice and Associates With Outcomes of Patients
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Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA
inferred← citeshttps://doi.org/10.1080/14760584.2018.1425619openalex-snapshot
Passive and active antibody studies in primates to inform HIV vaccines
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Progress Towards a Therapeutic HIV DNA Vaccine
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From natural defenders to therapeutic warriors: NK cells in HIV immunotherapy
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Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses
inferred← citeshttps://doi.org/10.1080/21645515.2020.1765622openalex-snapshot
The importance of semen leukocytes in HIV-1 transmission and the development of prevention strategies
inferred← citeshttps://doi.org/10.1080/22221751.2024.2432345openalex-snapshot
Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches
inferred← citeshttps://doi.org/10.1084/jem.20212045openalex-snapshot
Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller
inferred← citeshttps://doi.org/10.1089/aid.2016.0299openalex-snapshot
Beyond Viral Neutralization
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From Elimination to Eradication: The Role of an HIV Vaccine and/or Cure
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Phenotypic and functional characteristics of highly differentiated CD57+NKG2C+ NK cells in HIV-1-infected individuals
inferred← citeshttps://doi.org/10.1093/femspd/ftz043openalex-snapshot
Simulating the entire natural course of HIV infection by extending the basic viral dynamics equations to include declining viral clearance
inferred← citeshttps://doi.org/10.1093/infdis/jiaa165openalex-snapshot
Antibodies for Human Immunodeficiency Virus-1 Cure Strategies
inferred← citeshttps://doi.org/10.1093/jimmun/vkae028openalex-snapshot
Gene-modified NK cells expressing CD64 and preloaded with HIV-specific BNAbs target autologous HIV-1–infected CD4+ T cells by ADCC
inferred← citeshttps://doi.org/10.1093/jimmun/vkaf015openalex-snapshot
HIV-1 broadly neutralizing antibodies demonstrate a high propensity for binding to heme
inferred← citeshttps://doi.org/10.1093/jleuko/qiac007openalex-snapshot
Mapping the interplay between NK cells and HIV: therapeutic implications
inferred← citeshttps://doi.org/10.1093/jleuko/qiaf033openalex-snapshot
Afucosylated broadly neutralizing antibodies targeting the HIV envelope elicit enhanced NK-cell–mediated cytotoxicity against HIV-infected CD4+ T-cell and macrophage targets
inferred← citeshttps://doi.org/10.1093/med/9780197576595.003.0026openalex-snapshot
The HIV Reservoir and Cure and Remission Strategies
inferred← citeshttps://doi.org/10.1093/med/9780197679098.003.0019openalex-snapshot
The HIV Reservoir and Cure and Remission Strategies
inferred← citeshttps://doi.org/10.1093/med/9780197812631.003.0018openalex-snapshot
The HIV Reservoir and Cure and Remission Strategies
inferred← citeshttps://doi.org/10.1093/ofid/ofy242openalex-snapshot
Randomized Clinical Trial to Assess the Impact of the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 on HIV-1 Persistence in Individuals on Effective ART
inferred← citeshttps://doi.org/10.1097/coh.0000000000000439openalex-snapshot
Anti-HIV-1 antibody-dependent cellular cytotoxicity
inferred← citeshttps://doi.org/10.1097/coh.0000000000000475openalex-snapshot
Broadly neutralizing antibodies for treatment and prevention of HIV-1 infection
inferred← citeshttps://doi.org/10.1097/coh.0000000000000600openalex-snapshot
Broadly neutralizing antibodies for the treatment and prevention of HIV infection
inferred← citeshttps://doi.org/10.1097/coh.0000000000000644openalex-snapshot
Roles of fragment crystallizable-mediated effector functions in broadly neutralizing antibody activity against HIV
inferred← citeshttps://doi.org/10.1097/coh.0000000000000799openalex-snapshot
Polyfunctionality of broadly neutralizing HIV-1 antibodies
inferred← citeshttps://doi.org/10.1097/coh.0000000000000802openalex-snapshot
Broadly neutralizing antibodies for HIV treatment and cure approaches
inferred← citeshttps://doi.org/10.1097/coh.0000000000000840openalex-snapshot
Harnessing immune cells to eliminate HIV reservoirs
inferred← citeshttps://doi.org/10.1097/coh.0000000000000889openalex-snapshot
Soluble markers of viral rebound and post-treatment HIV control
inferred← citeshttps://doi.org/10.1097/coh.0000000000000893openalex-snapshot
Humoral immunity in HIV-1 post-treatment controllers
inferred← citeshttps://doi.org/10.1097/coh.0000000000000909openalex-snapshot
Elephant in the room: natural killer cells don’t forget HIV either
inferred← citeshttps://doi.org/10.1097/coh.0000000000000928openalex-snapshot
New developments in antiretroviral therapy strategies to improve clinical management of neonates and young infants with HIV
inferred← citeshttps://doi.org/10.1097/coh.0000000000000972openalex-snapshot
Harnessing innate immunity: natural killer cells and innate immune responses in reservoir clearance
inferred← citeshttps://doi.org/10.1097/coh.0000000000001034openalex-snapshot
Natural killer cells in pediatric HIV cure strategies: from viral control to immunotherapeutics
inferred← citeshttps://doi.org/10.1097/qad.0000000000001380openalex-snapshot
IFN-α augments natural killer-mediated antibody-dependent cellular cytotoxicity of HIV-1-infected autologous CD4+ T cells regardless of major histocompatibility complex class 1 downregulation
inferred← citeshttps://doi.org/10.1097/qad.0000000000001460openalex-snapshot
Humoral responses against HIV in male genital tract
inferred← citeshttps://doi.org/10.1097/qad.0000000000001645openalex-snapshot
Natural killer cells in HIV-1 infection and therapy
inferred← citeshttps://doi.org/10.1097/qad.0000000000001869openalex-snapshot
A defucosylated bispecific multivalent molecule exhibits broad HIV-1-neutralizing activity and enhanced antibody-dependent cellular cytotoxicity against reactivated HIV-1 latently infected cells
inferred← citeshttps://doi.org/10.1097/qad.0000000000002011openalex-snapshot
Antibody-dependent cellular cytotoxicity in HIV infection
inferred← citeshttps://doi.org/10.1097/qad.0000000000002976openalex-snapshot
Coordinated Fc-effector and neutralization functions in HIV-infected children define a window of opportunity for HIV vaccination
inferred← citeshttps://doi.org/10.1097/qad.0000000000003319openalex-snapshot
Natural killer cells during acute HIV-1 infection: clues for HIV-1 prevention and therapy
inferred← citeshttps://doi.org/10.1097/qad.0000000000004115openalex-snapshot
Broadly neutralizing antibodies, nonneutralizing antibodies and broadly effector antibodies to prevent HIV transmission?
inferred← citeshttps://doi.org/10.1101/2021.06.16.448593openalex-snapshot
A Remarkable Genetic Shift in a Transmitted/Founder Virus Broadens Antibody Responses Against HIV-1
inferred← citeshttps://doi.org/10.1101/2022.09.05.506592openalex-snapshot
Reduction of the HIV-1 reservoir in T cells from persons with HIV-1 on suppressive antiretroviral therapy using expanded natural killer cells ex vivo
inferred← citeshttps://doi.org/10.1101/2024.06.20.599937openalex-snapshot
Gene-modified NK Cells Expressing CD64 and Pre-loaded with HIV-specific BNAbs Target Autologous HIV-1 Infected CD4 + T Cells by ADCC
inferred← citeshttps://doi.org/10.1101/2025.08.06.668975openalex-snapshot
Synergistic latency reversal by the IAP antagonist AZD5582 and BET inhibitor JQ1, combined with Nef ablation, facilitates immune-mediated elimination of latently HIV-1-infected T-cells
inferred← citeshttps://doi.org/10.1101/2025.11.12.688078openalex-snapshot
Functional Activity of HIV-1 bNAbs Across Diverse Strains is Driven by Binding Site and Can be Enhanced Through Fc Engineering
inferred← citeshttps://doi.org/10.1101/221010openalex-snapshot
HIV-1-induced cytokines deplete homeostatic ILCs and expand TCF7-dependent memory NK cells: Supplemental Figures and Tables
inferred← citeshttps://doi.org/10.1111/hiv.70197openalex-snapshot
Immune non‐response despite effective antiretroviral therapy in people living with HIV : A review of potential mechanisms, biomarkers and therapeutic approaches
inferred← citeshttps://doi.org/10.1111/imr.12511openalex-snapshot
Use of broadly neutralizing antibodies for HIV ‐1 prevention
inferred← citeshttps://doi.org/10.1111/imr.13393openalex-snapshot
Fc‐ FcγR interactions during infections: From neutralizing antibodies to antibody‐dependent enhancement
inferred← citeshttps://doi.org/10.1111/pbi.13090openalex-snapshot
A novel anti‐HIV‐1 bispecific bNAb‐lectin fusion protein engineered in a plant‐based transient expression system
inferred← citeshttps://doi.org/10.1126/sciimmunol.adq4973openalex-snapshot
Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy
inferred← citeshttps://doi.org/10.1126/scitranslmed.aaf1483openalex-snapshot
Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection
inferred← citeshttps://doi.org/10.1126/scitranslmed.aaz2254openalex-snapshot
An amphipathic peptide targeting the gp41 cytoplasmic tail kills HIV-1 virions and infected cells
inferred← citeshttps://doi.org/10.1128/jvi.00235-18openalex-snapshot
Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo
inferred← citeshttps://doi.org/10.1128/jvi.00293-19openalex-snapshot
Antibody-Induced Internalization of HIV-1 Env Proteins Limits Surface Expression of the Closed Conformation of Env
inferred← citeshttps://doi.org/10.1128/jvi.00347-16openalex-snapshot
Comparison of Antibody-Dependent Cell-Mediated Cytotoxicity and Virus Neutralization by HIV-1 Env-Specific Monoclonal Antibodies
inferred← citeshttps://doi.org/10.1128/jvi.00603-17openalex-snapshot
Anti-HIV-1 ADCC Antibodies following Latency Reversal and Treatment Interruption
inferred← citeshttps://doi.org/10.1128/jvi.00634-17openalex-snapshot
Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the HIV-1 Reservoir
inferred← citeshttps://doi.org/10.1128/jvi.00793-20openalex-snapshot
SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques
inferred← citeshttps://doi.org/10.1128/jvi.00895-18openalex-snapshot
Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs
inferred← citeshttps://doi.org/10.1128/jvi.00937-17openalex-snapshot
PotentIn VivoNK Cell-Mediated Elimination of HIV-1-Infected Cells Mobilized by a gp120-Bispecific and Hexavalent Broadly Neutralizing Fusion Protein
inferred← citeshttps://doi.org/10.1128/jvi.01246-19openalex-snapshot
A MUC16 IgG Binding Activity Selects for a Restricted Subset of IgG Enriched for Certain Simian Immunodeficiency Virus Epitope Specificities
inferred← citeshttps://doi.org/10.1128/jvi.01446-18openalex-snapshot
Neutralization Synergy between HIV-1 Attachment Inhibitor Fostemsavir and Anti-CD4 Binding Site Broadly Neutralizing Antibodies against HIV
inferred← citeshttps://doi.org/10.1128/jvi.01485-25openalex-snapshot
Dissecting the steps in early simian immunodeficiency virus dissemination following mucosal and intravenous infection of rhesus macaques
inferred← citeshttps://doi.org/10.1128/jvi.01620-25openalex-snapshot
Retinoids enhance NK effector function against HIV-infected CD4 T cells
inferred← citeshttps://doi.org/10.1128/jvi.01625-21openalex-snapshot
Evolution of Antibodies to Native Trimeric Envelope and Their Fc-Dependent Functions in Untreated and Treated Primary HIV Infection
inferred← citeshttps://doi.org/10.1128/jvi.01635-22openalex-snapshot
Evolution of Antibody Responses in HIV-1 CRF01_AE Acute Infection: Founder Envelope V1V2 Impacts the Timing and Magnitude of Autologous Neutralizing Antibodies
inferred← citeshttps://doi.org/10.1128/jvi.01643-21openalex-snapshot
Selection of HIV Envelope Strains for Standardized Assessments of Vaccine-Elicited Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies
inferred← citeshttps://doi.org/10.1128/jvi.01667-20openalex-snapshot
Systematic Assessment of Antiviral Potency, Breadth, and Synergy of Triple Broadly Neutralizing Antibody Combinations against Simian-Human Immunodeficiency Viruses
inferred← citeshttps://doi.org/10.1128/jvi.01684-17openalex-snapshot
Etude fonctionnelle des glycoprotéines d'enveloppe du réservoir VIH-1
inferred← citeshttps://doi.org/10.1128/jvi.01783-19openalex-snapshot
Flow Cytometry Analysis of HIV-1 Env Conformations at the Surface of Infected Cells and Virions: Role of Nef, CD4, and SERINC5
inferred← citeshttps://doi.org/10.1128/jvi.01808-20openalex-snapshot
Relationships between Neutralization, Binding, and ADCC of Broadly Neutralizing Antibodies against Reservoir HIV
inferred← citeshttps://doi.org/10.1128/jvi.02051-18openalex-snapshot
Establishment of a Novel Humanized Mouse Model To Investigate In Vivo Activation and Depletion of Patient-Derived HIV Latent Reservoirs
inferred← citeshttps://doi.org/10.1128/jvi.02296-16openalex-snapshot
Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents
inferred← citeshttps://doi.org/10.1128/jvi.02440-16openalex-snapshot
Lack of ADCC Breadth of Human Nonneutralizing Anti-HIV-1 Antibodies
inferred← citeshttps://doi.org/10.1128/mbio.00358-18openalex-snapshot
Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses
inferred← citeshttps://doi.org/10.1128/mbio.00789-23openalex-snapshot
Impact of HIV-1 Vpu-mediated downregulation of CD48 on NK-cell-mediated antibody-dependent cellular cytotoxicity
inferred← citeshttps://doi.org/10.1128/mbio.01255-19openalex-snapshot
Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIV smm/mac Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization
inferred← citeshttps://doi.org/10.1128/mbio.01900-24openalex-snapshot
Underappreciated layers of antibody-mediated immune synapse architecture and dynamics
inferred← citeshttps://doi.org/10.1128/mbio.02424-20openalex-snapshot
Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier
inferred← citeshttps://doi.org/10.1128/mbio.02690-19openalex-snapshot
Antibody-Dependent Cellular Cytotoxicity-Competent Antibodies against HIV-1-Infected Cells in Plasma from HIV-Infected Subjects
inferred← citeshttps://doi.org/10.1128/mbio.02807-25openalex-snapshot
mGem: Opening Env and harnessing NK cell effector functions to eliminate HIV-1-infected cells
inferred← citeshttps://doi.org/10.1128/mbio.02956-25openalex-snapshot
Reduction of the HIV-1 reservoir in T cells from people with HIV-1 on suppressive antiretroviral therapy using expanded natural killer cells
inferred← citeshttps://doi.org/10.1128/mbio.03839-24openalex-snapshot
Engineering of CD8 + T cells with an HIV-specific synthetic notch receptor to secrete broadly therapeutic antibodies for combining antiviral humoral and cellular immune responses
inferred← citeshttps://doi.org/10.1172/jci.insight.88226openalex-snapshot
Enhanced FCGR2A and FCGR3A signaling by HIV viremic controller IgG
inferred← citeshttps://doi.org/10.1172/jci.insight.97339openalex-snapshot
Neutrophils are essential for induction of vaccine-like effects by antiviral monoclonal antibody immunotherapies
inferred← citeshttps://doi.org/10.1172/jci122466openalex-snapshot
Fc-dependent functions are redundant to efficacy of anti-HIV antibody PGT121 in macaques
inferred← citeshttps://doi.org/10.1172/jci135557openalex-snapshot
Improved killing of HIV-infected cells using three neutralizing and non-neutralizing antibodies
inferred← citeshttps://doi.org/10.1172/jci153204openalex-snapshot
HIV-specific CAR T cells return to the clinic
inferred← citeshttps://doi.org/10.1172/jci97555openalex-snapshot
Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells
inferred← citeshttps://doi.org/10.1177/08892229251370763openalex-snapshot
The Immunogenicity of AAV-Encoded HIV-1 bNAbs in Rhesus Macaques Is Unaffected by a Short Course of the Immunomodulator CTLA4Ig
inferred← citeshttps://doi.org/10.1177/2515135518800689openalex-snapshot
Broadly neutralizing antibodies in HIV-1 treatment and prevention
inferred← citeshttps://doi.org/10.1182/blood.2025032142openalex-snapshot
Antigen-boosted CD4CAR T cells fail to expand or control viremia in multiple nonhuman primate models of HIV
inferred← citeshttps://doi.org/10.1186/s12879-017-2683-3openalex-snapshot
Landscape review of current HIV ‘kick and kill’ cure research - some kicking, not enough killing
inferred← citeshttps://doi.org/10.1186/s12977-018-0433-2openalex-snapshot
Broadly neutralizing antibodies: What is needed to move from a rare event in HIV-1 infection to vaccine efficacy?
inferred← citeshttps://doi.org/10.1186/s12977-018-0434-1openalex-snapshot
HIV-1 cell-to-cell transmission and broadly neutralizing antibodies
inferred← citeshttps://doi.org/10.1186/s12977-018-0438-xopenalex-snapshot
Importance of Fc-mediated functions of anti-HIV-1 broadly neutralizing antibodies
inferred← citeshttps://doi.org/10.1186/s12977-018-0449-7openalex-snapshot
Adeno-associated virus gene delivery of broadly neutralizing antibodies as prevention and therapy against HIV-1
inferred← citeshttps://doi.org/10.1186/s12977-021-00560-6openalex-snapshot
Characterisation of a highly potent and near pan-neutralising anti-HIV monoclonal antibody expressed in tobacco plants
inferred← citeshttps://doi.org/10.1186/s12981-017-0168-5openalex-snapshot
Unlocking HIV-1 Env: implications for antibody attack
inferred← citeshttps://doi.org/10.1186/s12985-025-03042-9openalex-snapshot
Learning from nature: HIV elite controllers as blueprints for a functional cure
inferred← citeshttps://doi.org/10.12688/f1000research.8109.1openalex-snapshot
Targeting the latent reservoir to achieve functional HIV cure
inferred← citeshttps://doi.org/10.1371/journal.pone.0167640openalex-snapshot
Increased Natural Killer Cell Activation in HIV-Infected Immunologic Non-Responders Correlates with CD4+ T Cell Recovery after Antiretroviral Therapy and Viral Suppression
inferred← citeshttps://doi.org/10.1371/journal.ppat.1008082openalex-snapshot
IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and in vivo half-life: Potential application in combination with broad neutralizing antibodies
inferred← citeshttps://doi.org/10.1371/journal.ppat.1010470openalex-snapshot
Plasma antibodies from humans infected with zoonotic simian foamy virus do not inhibit cell-to-cell transmission of the virus despite binding to the surface of infected cells
inferred← citeshttps://doi.org/10.1371/journal.ppat.1011407openalex-snapshot
Antibody-dependent cellular cytotoxicity, infected cell binding and neutralization by antibodies to the SIV envelope glycoprotein
inferred← citeshttps://doi.org/10.1371/journal.ppat.1011819openalex-snapshot
Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge
inferred← citeshttps://doi.org/10.15252/embr.201949351openalex-snapshot
Anti‐HIV‐1 antibodies trigger non‐lytic complement deposition on infected cells
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