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ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ijc.22074openalex-snapshot
Melanocortin 1 receptor variants and skin cancer risk
inferredcites →https://doi.org/10.1002/ijc.23257openalex-snapshot
MC1R variants associated susceptibility to basal cell carcinoma of skin: Interaction with host factors and XRCC3 polymorphism
inferredcites →https://doi.org/10.1016/j.jdermsci.2005.08.001openalex-snapshot
Association study of the g.8818A > G polymorphism of the human agouti gene with melanoma risk and pigmentary characteristics in a French population
inferredcites →https://doi.org/10.1016/j.peptides.2004.11.021openalex-snapshot
The relation between melanocortin 1 receptor (MC1R) variation and the generation of phenotypic diversity in the cutaneous response to ultraviolet radiation
inferredcites →https://doi.org/10.1016/j.tig.2004.06.010openalex-snapshot
Eye colour: portals into pigmentation genes and ancestry
inferredcites →https://doi.org/10.1016/s0025-6196(11)61033-1openalex-snapshot
Malignant Melanoma in the 21st Century, Part 1: Epidemiology, Risk Factors, Screening, Prevention, and Diagnosis
inferredcites →https://doi.org/10.1016/s0190-9622(08)81509-5openalex-snapshot
Nonmelanoma skin cancer in the United States: Incidence
inferredcites →https://doi.org/10.1034/j.1600-0749.2002.00039.xopenalex-snapshot
Agouti: from Mouse to Man, from Skin to Fat
inferredcites →https://doi.org/10.1038/ng.160openalex-snapshot
Two newly identified genetic determinants of pigmentation in Europeans
inferredcites →https://doi.org/10.1038/ng.2007.13openalex-snapshot
Genetic determinants of hair, eye and skin pigmentation in Europeans
inferredcites →https://doi.org/10.1038/ng1245openalex-snapshot
The gene encoding phosphodiesterase 4D confers risk of ischemic stroke
inferredcites →https://doi.org/10.1038/ng1732openalex-snapshot
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
inferredcites →https://doi.org/10.1038/ng2064openalex-snapshot
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer
inferredcites →https://doi.org/10.1038/sj.jid.5700345openalex-snapshot
Plenty New Under the Sun
inferredcites →https://doi.org/10.1046/j.0022-202x.2001.01421.xopenalex-snapshot
Melanocortin 1 Receptor (MC1R) Gene Variants are Associated with an Increased Risk for Cutaneous Melanoma Which is Largely Independent of Skin Type and Hair Color
inferredcites →https://doi.org/10.1046/j.1523-1747.2001.01224.xopenalex-snapshot
Melanocortin-1 Receptor Genotype is a Risk Factor for Basal and Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1086/302711openalex-snapshot
Melanocortin-1 Receptor Polymorphisms and Risk of Melanoma: Is the Association Explained Solely by Pigmentation Phenotype?
inferredcites →https://doi.org/10.1086/319500openalex-snapshot
Melanocortin-1 Receptor Gene Variants Determine the Risk of Nonmelanoma Skin Cancer Independently of Fair Skin and Red Hair
inferredcites →https://doi.org/10.1086/339076openalex-snapshot
A Polymorphism in the Agouti Signaling Protein Gene Is Associated with Human Pigmentation
inferredcites →https://doi.org/10.1086/510885openalex-snapshot
A Three–Single-Nucleotide Polymorphism Haplotype in Intron 1 of OCA2 Explains Most Human Eye-Color Variation
inferredcites →https://doi.org/10.1093/genetics/165.4.2071openalex-snapshot
Sequences Associated With Human Iris Pigmentation
inferredcites →https://doi.org/10.1093/hmg/5.10.1663openalex-snapshot
The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma
inferredcites →https://doi.org/10.1093/ije/dyl197openalex-snapshot
Risk factors for skin cancers: a nested case–control study within the Nurses’ Health Study
inferredcites →https://doi.org/10.1093/jnci/dji176openalex-snapshot
MC1R, ASIP, and DNA Repair in Sporadic and Familial Melanoma in a Mediterranean Population
inferredcites →https://doi.org/10.1093/nar/gkl679openalex-snapshot
A novel endonuclease IV post-PCR genotyping system
inferredcites →https://doi.org/10.1111/1523-1747.ep12292572openalex-snapshot
Agouti Signaling Protein Inhibits Melanogenesis and the Response of Human Melanocytes to α-Melanotropin
inferredcites →https://doi.org/10.1111/j.1365-2133.2006.07229.xopenalex-snapshot
Genetics and risk factors for basal cell carcinoma
inferredcites →https://doi.org/10.1136/adc.2005.086918openalex-snapshot
Sun exposure and risk of melanoma
inferredcites →https://doi.org/10.1172/jci115064openalex-snapshot
Temperature-sensitive tyrosinase associated with peripheral pigmentation in oculocutaneous albinism.
inferredcites →https://doi.org/10.3322/canjclin.57.1.43openalex-snapshot
Cancer Statistics, 2007

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Molecular Biology
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Does MC1R genotype convey information about melanoma risk beyond risk phenotypes?
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Characteristics of the coexistence of melanoma and renal cell carcinoma
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Genome‐wide linkage analysis of Swedish families to identify putative susceptibility loci for cutaneous malignant melanoma
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MC1R, ASIP, TYR, and TYRP1 gene variants in a population‐based series of multiple primary melanomas
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Truncating mutations of TP53AIP1 gene predispose to cutaneous melanoma
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Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians
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The association between Parkinson's disease and melanoma
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Variants at chromosome 20 (ASIP locus) and melanoma risk
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Genes involved in the WNT and vesicular trafficking pathways are associated with melanoma predisposition
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Inherited variation at MC1R and ASIP and association with melanoma‐specific survival
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Molecular mechanisms of flavonoids in melanin synthesis and the potential for the prevention and treatment of melanoma
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Melanoma Pathogenesis
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Inherited Gene Mutations in Melanoma
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Genodermatoses: Inherited Diseases of the Skin
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Epidemiology and Risk Factors of Basal Cell Carcinoma
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Germline Mutations Associated Melanocytic Lesions
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Personalized, Evolutionary, and Ecological Dermatology
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Genome and Skin Cancer
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Melanoma Genetics and Genomics
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Molecular Epidemiology of Melanoma
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Etiology
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Heat-shock-induced tyrosinase gene ablation with CRISPR in zebrafish
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Genetic risk factors for melanoma
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Metazoan innovation: from aromatic amino acids to extracellular signaling
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MC1R genotype may modify the effect of sun exposure on melanoma risk in the GEM study
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ASIP genetic variants and the number of non-melanoma skin cancers
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The Epidemiology of Melanoma of the Skin
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The Genetics of Skin Cancer
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The epidemiology of melanoma of the skin
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Updates of reactive oxygen species in melanoma etiology and progression
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Albinism: epidemiology, genetics, cutaneous characterization, psychosocial factors
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IRF4 Variants Have Age-Specific Effects on Nevus Count and Predispose to Melanoma
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A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR
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Mapping chromatin interactions at melanoma susceptibility loci uncovers distant cis-regulatory gene targets
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A UV-related risk analysis in ophthalmic malignancies: Increased UV exposure may cause ocular malignancies
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Investigation of a putative melanoma susceptibility locus at chromosome 3q29
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High SLC7A11 expression in normal skin of melanoma patients
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Hereditary Melanoma
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Melanoma Epidemiology and Public Health
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MC1R variant alleles and malignant melanoma risk in Israel
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Variants of the xeroderma pigmentosum variant gene (POLH) are associated with melanoma risk
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Vitamin D receptor gene polymorphisms, serum 25-hydroxyvitamin D levels, and melanoma: UK case–control comparisons and a meta-analysis of published VDR data
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High-ceiling diuretics are associated with an increased risk of basal cell carcinoma in a population-based follow-up study
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Relationship between sun exposure and melanoma risk for tumours in different body sites in a large case-control study in a temperate climate
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MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in Southern European populations: Results from a Meta-analysis
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Perceptions of genetic research and testing among members of families with an increased risk of malignant melanoma
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Risk of subsequent cutaneous malignancy in patients with prior keratinocyte carcinoma: A systematic review and meta-analysis
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Novel loss-of-function variant in DENND5A impedes melanosomal cargo transport and predisposes to familial cutaneous melanoma
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Applications of Genomics in Melanoma Oncogene Discovery
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Melanoma Epidemiology
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Inverse Relationship between Vitiligo-Related Genes and Skin Cancer Risk
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Inherited Genetic Variants Associated with Melanoma BRAF/NRAS Subtypes
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Cells to Surgery Quiz: September 2021
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Pigmentation genes link Parkinson’s disease to melanoma, opening a window on both etiologies
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Synthetic aromatic compounds interfering with melanogenesis are responsible of the rising trend of malignant melanoma incidence
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Association of the 16q24.3 region gene variants rs1805007 and rs4785763 with heightened risk of melanoma in Latvian population
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Tyrosinase related protein 1 (TYRP1/gp75) in human cutaneous melanoma
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Single-nucleotide polymorphisms in DNA-repair genes and cutaneous melanoma
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Genetics of pigmentation in skin cancer — A review
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Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease
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Evolución de la pigmentación en la especie humana
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Genetic Determinants of Cutaneous Melanoma Predisposition
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Specification and loss of melanocyte stem cells
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Colorful DNA polymorphisms in humans
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Mendelian Randomization Analysis reveals Inverse Genetic Risks between Skin Cancers and Vitiligo
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Identification of Associations with Dermatologic Diseases through a Focused GWAS of the UK Biobank
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Evaluation of Actinic Keratosis as a Risk Factor for Subsequent Nonskin Cancer Risk
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Non-melanoma skin cancer
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Quoi de neuf en recherche dermatologique ?
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Chapter 4 The Melanocortin‐1 Receptor Gene Polymorphism and Association with Human Skin Cancer
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Genome-wide association studies of cancer predisposition
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Molecular oncology of basal cell carcinomas
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An Unusual Conformation of γ-Melanocyte-Stimulating Hormone Analogues Leads to a Selective Human Melanocortin 1 Receptor Antagonist for Targeting Melanoma Cells
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The delicate balance of melanoma immunotherapy
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Joint analysis of tightly linked SNPs in screening step of genome-wide association studies leads to increased power
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Multiple Pigmentation Gene Polymorphisms Account for a Substantial Proportion of Risk of Cutaneous Malignant Melanoma
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CHEK2*1100delC and Risk of Malignant Melanoma: Danish and German Studies and Meta-Analysis
inferred← citeshttps://doi.org/10.1038/jid.2011.321openalex-snapshot
Six Decades of Vitiligo Genetics: Genome-Wide Studies Provide Insights into Autoimmune Pathogenesis
inferred← citeshttps://doi.org/10.1038/jid.2011.402openalex-snapshot
Host Phenotype Characteristics and MC1R in Relation to Early-Onset Basal Cell Carcinoma
inferred← citeshttps://doi.org/10.1038/jid.2012.4openalex-snapshot
A Community-Based Study of Nucleotide Excision Repair Polymorphisms in Relation to the Risk of Non-Melanoma Skin Cancer
inferred← citeshttps://doi.org/10.1038/jid.2012.75openalex-snapshot
Melanoma Genetics: Recent Findings Take Us Beyond Well-Traveled Pathways
inferred← citeshttps://doi.org/10.1038/nature10630openalex-snapshot
A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma
inferred← citeshttps://doi.org/10.1038/nbt.2282openalex-snapshot
Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
inferred← citeshttps://doi.org/10.1038/nbt.2749openalex-snapshot
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
inferred← citeshttps://doi.org/10.1038/ncomms12048openalex-snapshot
Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma
inferred← citeshttps://doi.org/10.1038/ncomms7825openalex-snapshot
New basal cell carcinoma susceptibility loci
inferred← citeshttps://doi.org/10.1038/ncomms8033openalex-snapshot
Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes
inferred← citeshttps://doi.org/10.1038/ng.234openalex-snapshot
Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits
inferred← citeshttps://doi.org/10.1038/ng.2571openalex-snapshot
A variant in FTO shows association with melanoma risk not due to BMI
inferred← citeshttps://doi.org/10.1038/ng.296openalex-snapshot
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types
inferred← citeshttps://doi.org/10.1038/ng.323openalex-snapshot
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
inferred← citeshttps://doi.org/10.1038/ng.3373openalex-snapshot
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma
inferred← citeshttps://doi.org/10.1038/ng.411openalex-snapshot
Genome-wide association study identifies three loci associated with melanoma risk
inferred← citeshttps://doi.org/10.1038/ng.412openalex-snapshot
New common variants affecting susceptibility to basal cell carcinoma
inferred← citeshttps://doi.org/10.1038/ng.424openalex-snapshot
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2
inferred← citeshttps://doi.org/10.1038/ng.926openalex-snapshot
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
inferred← citeshttps://doi.org/10.1038/ng.958openalex-snapshot
Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3
inferred← citeshttps://doi.org/10.1038/ng.959openalex-snapshot
Genome-wide association study identifies three new melanoma susceptibility loci
inferred← citeshttps://doi.org/10.1038/ng0708-817openalex-snapshot
Shedding light on skin cancer
inferred← citeshttps://doi.org/10.1038/nrc.2017.82openalex-snapshot
Genome-wide association studies of cancer: current insights and future perspectives
inferred← citeshttps://doi.org/10.1038/nrc2503openalex-snapshot
Basal cell carcinomas: attack of the hedgehog
inferred← citeshttps://doi.org/10.1038/nrc2840openalex-snapshot
Architecture of inherited susceptibility to common cancer
inferred← citeshttps://doi.org/10.1038/nrg2409openalex-snapshot
Pigmentation and skin-cancer risk
inferred← citeshttps://doi.org/10.1038/s41416-022-01923-2openalex-snapshot
Associations between circulating proteins and risk of breast cancer by intrinsic subtypes: a Mendelian randomisation analysis
inferred← citeshttps://doi.org/10.1038/s41467-020-16067-1openalex-snapshot
Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors
inferred← citeshttps://doi.org/10.1038/s41467-020-16590-1openalex-snapshot
Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma
inferred← citeshttps://doi.org/10.1038/s41531-024-00638-wopenalex-snapshot
Discovering genetic mechanisms underlying the co-occurrence of Parkinson’s disease and non-motor traits
inferred← citeshttps://doi.org/10.1038/s41588-024-01841-4openalex-snapshot
A sequence of SVA retrotransposon insertions in ASIP shaped human pigmentation
inferred← citeshttps://doi.org/10.1038/s41588-024-01849-wopenalex-snapshot
Mobile element insertions affect human pigmentation and skin cancer risk
inferred← citeshttps://doi.org/10.1039/c0pp90044copenalex-snapshot
The human health effects of ozone depletion and interactions with climate change
inferred← citeshttps://doi.org/10.1051/medsci/2011272153openalex-snapshot
La biogenèse des mélanosomes
inferred← citeshttps://doi.org/10.1053/j.seminoncol.2012.01.011openalex-snapshot
Advances in the Treatment of Basal Cell Carcinoma: Hedgehog Inhibitors
inferred← citeshttps://doi.org/10.1053/j.seminoncol.2016.08.003openalex-snapshot
Genetic predisposition to melanoma
inferred← citeshttps://doi.org/10.1056/jd200806060000001openalex-snapshot
Genotypes for Pigmentation and Skin Cancer
inferred← citeshttps://doi.org/10.1056/nejmoa0908547openalex-snapshot
Variant of TYR and Autoimmunity Susceptibility Loci in Generalized Vitiligo
inferred← citeshttps://doi.org/10.1073/pnas.0806753106openalex-snapshot
Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1r
inferred← citeshttps://doi.org/10.1073/pnas.2525288123openalex-snapshot
Scalable and accurate rare-variant association tests for whole genome sequencing time-to-event analysis in large biobanks
inferred← citeshttps://doi.org/10.1089/thy.2010.1643openalex-snapshot
Shared Genetic Relationships Underlying Generalized Vitiligo and Autoimmune Thyroid Disease
inferred← citeshttps://doi.org/10.1093/annonc/mdp252openalex-snapshot
Epidemiology of invasive cutaneous melanoma
inferred← citeshttps://doi.org/10.1093/annonc/mdz247.134openalex-snapshot
Investigation on gastric cancer susceptibility genes in Chinese early-onset diffuse gastric cancer
inferred← citeshttps://doi.org/10.1093/bib/bbaf564openalex-snapshot
Genetic imputation of transcriptome and proteome illuminates novel therapeutic targets of cutaneous melanoma
inferred← citeshttps://doi.org/10.1093/biomet/asy064openalex-snapshot
Counting process-based dimension reduction methods for censored outcomes
inferred← citeshttps://doi.org/10.1093/bmb/ldq038openalex-snapshot
Genome-wide association studies for detecting cancer susceptibility
inferred← citeshttps://doi.org/10.1093/carcin/bgu140openalex-snapshot
Identification of a melanoma susceptibility locus and somatic mutation inTET2
inferred← citeshttps://doi.org/10.1093/carcin/bgz173openalex-snapshot
Functional annotation of melanoma risk loci identifies novel susceptibility genes
inferred← citeshttps://doi.org/10.1093/cei/uxab002openalex-snapshot
Patho-immunological mechanisms of vitiligo: the role of the innate and adaptive immunities and environmental stress factors
inferred← citeshttps://doi.org/10.1093/genetics/iyaf204openalex-snapshot
Mutation ages and population origins inferred from genomes in structured populations
inferred← citeshttps://doi.org/10.1093/hmg/ddn287openalex-snapshot
Genome-wide association studies in cancer
inferred← citeshttps://doi.org/10.1093/hmg/ddp003openalex-snapshot
Molecular genetics of human pigmentation diversity
inferred← citeshttps://doi.org/10.1093/hmg/ddr287openalex-snapshot
Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma
inferred← citeshttps://doi.org/10.1093/hmg/ddr415openalex-snapshot
Genome-wide association study identifies novel loci predisposing to cutaneous melanoma†
inferred← citeshttps://doi.org/10.1093/hmg/dds381openalex-snapshot
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11
inferred← citeshttps://doi.org/10.1093/hmg/ddt671openalex-snapshot
Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma
inferred← citeshttps://doi.org/10.1093/hmg/ddv076openalex-snapshot
IRF4, MC1R and TYR genes are risk factors for actinic keratosis independent of skin color
inferred← citeshttps://doi.org/10.1093/jnci/djn437openalex-snapshot
A Field Synopsis on Low-Penetrance Variants in DNA Repair Genes and Cancer Susceptibility
inferred← citeshttps://doi.org/10.1093/jnci/djr219openalex-snapshot
Comprehensive Field Synopsis and Systematic Meta-analyses of Genetic Association Studies in Cutaneous Melanoma
inferred← citeshttps://doi.org/10.1093/jnci/djw004openalex-snapshot
Association of Interferon Regulatory Factor-4 Polymorphism rs12203592 With Divergent Melanoma Pathways
inferred← citeshttps://doi.org/10.1093/med/9780198746690.003.0563openalex-snapshot
Tumours of the skin
inferred← citeshttps://doi.org/10.1097/cmr.0b013e328336b000openalex-snapshot
Melanoma susceptibility genes
inferred← citeshttps://doi.org/10.1097/cmr.0b013e32833b159dopenalex-snapshot
Influence of loss of function MC1R variants in genetic susceptibility of familial melanoma in Spain
inferred← citeshttps://doi.org/10.1097/gim.0b013e3181993175openalex-snapshot
Genetic testing for melanoma risk: a prospective cohort study of uptake and outcomes among Australian families
inferred← citeshttps://doi.org/10.1097/scs.0000000000010597openalex-snapshot
Mapping the Research on Periocular Basal Cell Carcinoma in the Past 20 Years: A Bibliometric Network Analysis
inferred← citeshttps://doi.org/10.1101/2020.08.25.20181610openalex-snapshot
Recommendations for Primary Prevention of Skin Melanoma
inferred← citeshttps://doi.org/10.1101/2024.09.16.613289openalex-snapshot
Proof of concept study deploying CRISPR inhibition and activation opens new avenues for systematic biological exploration in zebrafish
inferred← citeshttps://doi.org/10.1101/2024.11.14.24317204openalex-snapshot
Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of cis -regulation
inferred← citeshttps://doi.org/10.1101/2025.02.09.25321567openalex-snapshot
DeepSpot: Leveraging Spatial Context for Enhanced Spatial Transcriptomics Prediction from H&E Images
inferred← citeshttps://doi.org/10.1101/231423openalex-snapshot
Cell-type specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes
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