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Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/archgenpsychiatry.2011.151openalex-snapshot
Epigenetic Signatures of Autism
inferredcites →https://doi.org/10.1016/0020-711x(90)90333-xopenalex-snapshot
Regulation of mitochondrial ATP synthesis in mammalian cells by transcriptional control
inferredcites →https://doi.org/10.1016/j.bbagrm.2012.08.008openalex-snapshot
Transcription-associated histone modifications and cryptic transcription
inferredcites →https://doi.org/10.1016/j.cell.2007.05.009openalex-snapshot
High-Resolution Profiling of Histone Methylations in the Human Genome
inferredcites →https://doi.org/10.1016/j.cell.2009.04.056openalex-snapshot
Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer
inferredcites →https://doi.org/10.1016/j.cell.2010.03.030openalex-snapshot
c-Myc Regulates Transcriptional Pause Release
inferredcites →https://doi.org/10.1016/j.cell.2012.08.026openalex-snapshot
Transcriptional Amplification in Tumor Cells with Elevated c-Myc
inferredcites →https://doi.org/10.1016/j.cell.2012.08.033openalex-snapshot
c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2012.11.009openalex-snapshot
UpSET Recruits HDAC Complexes and Restricts Chromatin Accessibility and Acetylation at Promoter Regions
inferredcites →https://doi.org/10.1016/j.cell.2013.01.052openalex-snapshot
H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation
inferredcites →https://doi.org/10.1016/j.cell.2013.03.035openalex-snapshot
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
inferredcites →https://doi.org/10.1016/j.cell.2013.03.036openalex-snapshot
Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
inferredcites →https://doi.org/10.1016/j.cell.2013.04.022openalex-snapshot
Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2013.09.053openalex-snapshot
Super-Enhancers in the Control of Cell Identity and Disease
inferredcites →https://doi.org/10.1016/j.cell.2013.10.011openalex-snapshot
Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome
inferredcites →https://doi.org/10.1016/j.cell.2014.06.027openalex-snapshot
H3K4me3 Breadth Is Linked to Cell Identity and Transcriptional Consistency
inferredcites →https://doi.org/10.1016/j.jmb.2008.04.061openalex-snapshot
Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor Suppressor
inferredcites →https://doi.org/10.1016/j.molcel.2007.11.010openalex-snapshot
Recognition of Trimethylated Histone H3 Lysine 4 Facilitates the Recruitment of Transcription Postinitiation Factors and Pre-mRNA Splicing
inferredcites →https://doi.org/10.1016/j.molcel.2013.01.038openalex-snapshot
Modification of Enhancer Chromatin: What, How, and Why?
inferredcites →https://doi.org/10.1016/j.stem.2007.08.004openalex-snapshot
Whole-Genome Mapping of Histone H3 Lys4 and 27 Trimethylations Reveals Distinct Genomic Compartments in Human Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.tig.2013.05.010openalex-snapshot
Human housekeeping genes, revisited
inferredcites →https://doi.org/10.1038/emboj.2008.257openalex-snapshot
Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites
inferredcites →https://doi.org/10.1038/leu.2010.63openalex-snapshot
Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia
inferredcites →https://doi.org/10.1038/nature11273openalex-snapshot
Chromatin organization is a major influence on regional mutation rates in human cancer cells
inferredcites →https://doi.org/10.1038/nature12213openalex-snapshot
Mutational heterogeneity in cancer and the search for new cancer-associated genes
inferredcites →https://doi.org/10.1038/nbt.2030openalex-snapshot
DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes
inferredcites →https://doi.org/10.1038/ng.2764openalex-snapshot
The Cancer Genome Atlas Pan-Cancer analysis project
inferredcites →https://doi.org/10.1038/ng.2836openalex-snapshot
Large conserved domains of low DNA methylation maintained by Dnmt3a
inferredcites →https://doi.org/10.1038/nsmb1352openalex-snapshot
RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes
inferredcites →https://doi.org/10.1073/pnas.1001064107openalex-snapshot
Mutant Ikzf1, Kras G12D , and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents
inferredcites →https://doi.org/10.1073/pnas.1310156110openalex-snapshot
Molecular basis for chromatin binding and regulation of MLL5
inferredcites →https://doi.org/10.1074/jbc.m102306200openalex-snapshot
Flavopiridol Inactivates P-TEFb and Blocks Most RNA Polymerase II Transcription in Vivo
inferredcites →https://doi.org/10.1093/nar/gkt1249openalex-snapshot
Systematic discovery and characterization of regulatory motifs in ENCODE TF binding experiments
inferredcites →https://doi.org/10.1101/gr.109389.110openalex-snapshot
A unique H3K4me2 profile marks tissue-specific gene regulation
inferredcites →https://doi.org/10.1101/gr.139105.112openalex-snapshot
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
inferredcites →https://doi.org/10.1101/gr.142067.112openalex-snapshot
DANPOS: Dynamic analysis of nucleosome position and occupancy by sequencing
inferredcites →https://doi.org/10.1101/gr.171405.113openalex-snapshot
Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications
inferredcites →https://doi.org/10.1146/annurev.immunol.15.1.155openalex-snapshot
THE ROLE OF THE IKAROS GENE IN LYMPHOCYTE DEVELOPMENT AND HOMEOSTASIS
inferredcites →https://doi.org/10.1158/0008-5472.can-12-3150openalex-snapshot
Tumor Suppressor Function of the Plasma Glutathione Peroxidase Gpx3 in Colitis-Associated Carcinoma
inferredcites →https://doi.org/10.1182/blood-2009-02-206722openalex-snapshot
High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia
inferredcites →https://doi.org/10.1182/blood-2014-03-562751openalex-snapshot
PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events
inferredcites →https://doi.org/10.15252/embj.201490306openalex-snapshot
Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer
inferredcites →https://doi.org/10.18632/oncotarget.332openalex-snapshot
Polo Like Kinase 2 Tumour Suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in cancer
inferredcites →https://doi.org/10.4161/cc.5.12.2813openalex-snapshot
Epigenetic Inactivation Implies a Tumor Suppressor Function in Hematologic Malignancies for Polo-Like Kinase 2 but not Polo-Like Kinase 3
inferredcites →https://doi.org/10.4161/cc.8.24.10800openalex-snapshot
The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions
inferredcites →https://doi.org/10.7554/elife.02407openalex-snapshot
Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Histone H3K4me3 breadth in hypoxia reveals endometrial core functions and stress adaptation linked to endometriosis
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CFP1 promotes B cell class switch recombination through the regulation of S region germline transcription and proliferation
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Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription
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The methyltransferase MLL4 promotes nonalcoholic steatohepatitis by enhancing NF-κB signaling
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A tumor necrosis factor-α–responsive cryptic promoter drives overexpression of the human endogenous retrovirus ERVK-7
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The Genetics of Seborrheic Dermatitis: A Candidate Gene Approach and Pilot Genome-Wide Association Study
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Shortening the list of essential genes in the human genome by network analysis
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EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape
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ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription
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Determinants of Histone H3K4 Methylation Patterns
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MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes
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The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions
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CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release
inferred← citeshttps://doi.org/10.1016/j.molcel.2025.10.010openalex-snapshot
DNA bendability inside the nucleosome regulates INO80’s nucleosome positioning
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A Functional Role for the Epigenetic Regulator ING1 in Activity-induced Gene Expression in Primary Cortical Neurons
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Broad domains of histone 3 lysine 4 trimethylation are associated with transcriptional activation in CA1 neurons of the hippocampus during memory formation
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Unique Patterns of H3K4me3 and H3K27me3 in 2-Cell-like Embryonic Stem Cells
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Tumor suppressive activity of AHR in environmental arsenic-induced carcinogenesis
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Epigenome in Early Mammalian Development: Inheritance, Reprogramming and Establishment
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Roles of H3K4 methylation in biology and disease
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To incise or not and where: SET-domain methyltransferases know
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RNAPII driven post-translational modifications of nucleosomal histones
inferred← citeshttps://doi.org/10.1016/j.yexcr.2022.113158openalex-snapshot
MAFB promotes the malignant phenotypes by IGFBP6 in esophageal squamous cell carcinomas
inferred← citeshttps://doi.org/10.1016/j.ygeno.2021.12.008openalex-snapshot
Integrative epigenomic profiling reveal AP-1 is a key regulator in intrahepatic cholangiocarcinoma
inferred← citeshttps://doi.org/10.1016/j.ymthe.2022.01.038openalex-snapshot
The establishment of CDK9/RNA PolII/H3K4me3/DNA methylation feedback promotes HOTAIR expression by RNA elongation enhancement in cancer
inferred← citeshttps://doi.org/10.1016/j.ymthe.2024.08.019openalex-snapshot
Targeting ROS-sensing Nrf2 potentiates anti-tumor immunity of intratumoral CD8+ T and CAR-T cells
inferred← citeshttps://doi.org/10.1016/s0021-9258(17)49885-1openalex-snapshot
Proteasome inhibition creates a chromatin landscape favorable to RNA Pol II processivity
inferred← citeshttps://doi.org/10.1021/acs.jafc.5c15154openalex-snapshot
Dual Defense Strategy of GhRAP1 Gene: Coordinating Antibiosis and Antixenosis to Enhance Aphid Resistance in Plants
inferred← citeshttps://doi.org/10.1038/emm.2017.57openalex-snapshot
Histone lysine demethylases in mammalian embryonic development
inferred← citeshttps://doi.org/10.1038/nature19362openalex-snapshot
Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos
inferred← citeshttps://doi.org/10.1038/ncb3629openalex-snapshot
The impact of cellular metabolism on chromatin dynamics and epigenetics
inferred← citeshttps://doi.org/10.1038/s41375-018-0174-1openalex-snapshot
Drug targeting of NR4A nuclear receptors for treatment of acute myeloid leukemia
inferred← citeshttps://doi.org/10.1038/s41375-025-02638-yopenalex-snapshot
Regulation of H3K4me3 breadth and MYC expression by the SETD1B catalytic domain in MLL-rearranged leukemia
inferred← citeshttps://doi.org/10.1038/s41388-022-02311-zopenalex-snapshot
H3K4 demethylase KDM5B regulates cancer cell identity and epigenetic plasticity
inferred← citeshttps://doi.org/10.1038/s41392-025-02436-zopenalex-snapshot
Deciphering the regulatory landscape of enhancer RNAs in health and disease
inferred← citeshttps://doi.org/10.1038/s41392-025-02471-wopenalex-snapshot
Integrative analysis of non-small cell lung cancer identifies Jumonji domain-containing 6/ETS homologous factor axis as a target to overcome radioresistance
inferred← citeshttps://doi.org/10.1038/s41418-021-00808-wopenalex-snapshot
RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease
inferred← citeshttps://doi.org/10.1038/s41418-023-01189-yopenalex-snapshot
ASH2L regulates postnatal neurogenesis through Onecut2-mediated inhibition of TGF-β signaling pathway
inferred← citeshttps://doi.org/10.1038/s41419-020-03081-wopenalex-snapshot
The histone H2B ubiquitin ligase RNF40 is required for HER2-driven mammary tumorigenesis
inferred← citeshttps://doi.org/10.1038/s41419-020-2482-4openalex-snapshot
The H2B ubiquitin-protein ligase RNF40 is required for somatic cell reprogramming
inferred← citeshttps://doi.org/10.1038/s41419-022-04940-4openalex-snapshot
PHF13 epigenetically activates TGFβ driven epithelial to mesenchymal transition
inferred← citeshttps://doi.org/10.1038/s41422-025-01080-0openalex-snapshot
SETD1B-mediated broad H3K4me3 controls proper temporal patterns of gene expression critical for spermatid development
inferred← citeshttps://doi.org/10.1038/s41467-018-04426-yopenalex-snapshot
Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width
inferred← citeshttps://doi.org/10.1038/s41467-018-04552-7openalex-snapshot
Distinct epigenomic patterns are associated with haploinsufficiency and predict risk genes of developmental disorders
inferred← citeshttps://doi.org/10.1038/s41467-019-09784-9openalex-snapshot
LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling
inferred← citeshttps://doi.org/10.1038/s41467-019-10502-8openalex-snapshot
Mediator complex interaction partners organize the transcriptional network that defines neural stem cells
inferred← citeshttps://doi.org/10.1038/s41467-019-13550-2openalex-snapshot
Cryo-EM structure of the human MLL1 core complex bound to the nucleosome
inferred← citeshttps://doi.org/10.1038/s41467-020-16539-4openalex-snapshot
Machine learning uncovers cell identity regulator by histone code
inferred← citeshttps://doi.org/10.1038/s41467-020-18913-8openalex-snapshot
Broad genic repression domains signify enhanced silencing of oncogenes
inferred← citeshttps://doi.org/10.1038/s41467-020-19877-5openalex-snapshot
TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains
inferred← citeshttps://doi.org/10.1038/s41467-021-21707-1openalex-snapshot
Integrative pan cancer analysis reveals epigenomic variation in cancer type and cell specific chromatin domains
inferred← citeshttps://doi.org/10.1038/s41467-021-22448-xopenalex-snapshot
A compendium and comparative epigenomics analysis of cis-regulatory elements in the pig genome
inferred← citeshttps://doi.org/10.1038/s41467-021-26604-1openalex-snapshot
Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling
inferred← citeshttps://doi.org/10.1038/s41467-022-30484-4openalex-snapshot
PRRX1 is a master transcription factor of stromal fibroblasts for myofibroblastic lineage progression
inferred← citeshttps://doi.org/10.1038/s41467-022-33063-9openalex-snapshot
Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis
inferred← citeshttps://doi.org/10.1038/s41467-022-35444-6openalex-snapshot
Functional crosstalk between the cohesin loader and chromatin remodelers
inferred← citeshttps://doi.org/10.1038/s41467-023-38002-wopenalex-snapshot
Epigenetic landscape reveals MECOM as an endothelial lineage regulator
inferred← citeshttps://doi.org/10.1038/s41467-023-41245-2openalex-snapshot
TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition
inferred← citeshttps://doi.org/10.1038/s41467-024-46524-0openalex-snapshot
Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory
inferred← citeshttps://doi.org/10.1038/s41467-024-48990-yopenalex-snapshot
Cis-regulatory evolution of the recently expanded Ly49 gene family
inferred← citeshttps://doi.org/10.1038/s41467-024-54740-xopenalex-snapshot
Nuclear microRNA 9 mediates G-quadruplex formation and 3D genome organization during TGF-β-induced transcription
inferred← citeshttps://doi.org/10.1038/s41467-025-59780-5openalex-snapshot
CREATE: cell-type-specific cis-regulatory element identification via discrete embedding
inferred← citeshttps://doi.org/10.1038/s41467-025-63291-8openalex-snapshot
CFP1 promotes germinal center affinity maturation and restrains memory B cell differentiation through H3K4me3 modulation
inferred← citeshttps://doi.org/10.1038/s41467-025-67104-wopenalex-snapshot
Chemical reprogramming of fibroblasts into retinal pigment epithelium cells for vision restoration
inferred← citeshttps://doi.org/10.1038/s41525-021-00232-6openalex-snapshot
Loss of grand histone H3 lysine 27 trimethylation domains mediated transcriptional activation in esophageal squamous cell carcinoma
inferred← citeshttps://doi.org/10.1038/s41576-022-00468-7openalex-snapshot
Histone post-translational modifications — cause and consequence of genome function
inferred← citeshttps://doi.org/10.1038/s41586-023-05780-8openalex-snapshot
H3K4me3 regulates RNA polymerase II promoter-proximal pause-release
inferred← citeshttps://doi.org/10.1038/s41586-023-06585-5openalex-snapshot
Inhibition of fatty acid oxidation enables heart regeneration in adult mice
inferred← citeshttps://doi.org/10.1038/s41586-025-09400-5openalex-snapshot
Establishment of chromatin architecture interplays with embryo hypertranscription
inferred← citeshttps://doi.org/10.1038/s41588-018-0234-5openalex-snapshot
Single-molecule nascent RNA sequencing identifies regulatory domain architecture at promoters and enhancers
inferred← citeshttps://doi.org/10.1038/s41588-019-0485-9openalex-snapshot
NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements
inferred← citeshttps://doi.org/10.1038/s41588-023-01329-7openalex-snapshot
Distinct chromatin signatures in the Arabidopsis male gametophyte
inferred← citeshttps://doi.org/10.1038/s41594-025-01573-xopenalex-snapshot
H2A.Z reinforces maternal H3K4me3 formation and is essential for meiotic progression in mouse oocytes
inferred← citeshttps://doi.org/10.1038/s41598-017-02257-3openalex-snapshot
Super-Enhancers and Broad H3K4me3 Domains Form Complex Gene Regulatory Circuits Involving Chromatin Interactions
inferred← citeshttps://doi.org/10.1038/s41598-017-14389-7openalex-snapshot
Chromatin interaction networks revealed unique connectivity patterns of broad H3K4me3 domains and super enhancers in 3D chromatin
inferred← citeshttps://doi.org/10.1038/s41598-021-86919-3openalex-snapshot
Accessible chromatin reveals regulatory mechanisms underlying cell fate decisions during early embryogenesis
inferred← citeshttps://doi.org/10.1038/s41598-022-25881-0openalex-snapshot
Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters
inferred← citeshttps://doi.org/10.1038/s41598-023-38280-wopenalex-snapshot
Transcription and FACT facilitate the restoration of replication-coupled chromatin assembly defects
inferred← citeshttps://doi.org/10.1038/s41598-024-55189-0openalex-snapshot
Dynamic and distinct histone modifications facilitate human trophoblast lineage differentiation
inferred← citeshttps://doi.org/10.1038/s42003-025-09305-zopenalex-snapshot
Multi-omics elucidation of KDM5C, KDM6A, and KMT2B roles in cancer epigenetic dysregulation and transcriptional reprogramming
inferred← citeshttps://doi.org/10.1038/s44318-024-00329-5openalex-snapshot
Histone methyltransferases MLL2 and SETD1A/B play distinct roles in H3K4me3 deposition during the transition from totipotency to pluripotency
inferred← citeshttps://doi.org/10.1038/srep37942openalex-snapshot
Mitochondrial control through nutritionally regulated global histone H3 lysine-4 demethylation
inferred← citeshttps://doi.org/10.1042/bsr20160028openalex-snapshot
Homeobox genes gain trimethylation of histone H3 lysine 4 in glioblastoma tissue
inferred← citeshttps://doi.org/10.1053/j.gastro.2018.04.020openalex-snapshot
Germline Duplication of SNORA18L5 Increases Risk for HBV-related Hepatocellular Carcinoma by Altering Localization of Ribosomal Proteins and Decreasing Levels of p53
inferred← citeshttps://doi.org/10.1073/pnas.1708044114openalex-snapshot
5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes
inferred← citeshttps://doi.org/10.1073/pnas.1800656115openalex-snapshot
Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylation
inferred← citeshttps://doi.org/10.1073/pnas.2406519121openalex-snapshot
Phase separation of PML/RARα and BRD4 coassembled microspeckles governs transcriptional dysregulation in acute promyelocytic leukemia
inferred← citeshttps://doi.org/10.1074/jbc.ra118.002839openalex-snapshot
H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation
inferred← citeshttps://doi.org/10.1074/jbc.ra119.011174openalex-snapshot
Proteasome inhibition creates a chromatin landscape favorable to RNA Pol II processivity
inferred← citeshttps://doi.org/10.1080/10985549.2024.2388254openalex-snapshot
Functional Roles of H3K4 Methylation in Transcriptional Regulation
inferred← citeshttps://doi.org/10.1080/15592294.2018.1514231openalex-snapshot
Super-enhancers are transcriptionally more active and cell type-specific than stretch enhancers
inferred← citeshttps://doi.org/10.1080/15592294.2019.1582275openalex-snapshot
The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors
inferred← citeshttps://doi.org/10.1080/17501911.2026.2665450openalex-snapshot
The signaling upstream of DOT1L-mediated H3K79 methylation
inferred← citeshttps://doi.org/10.1080/21541264.2020.1843958openalex-snapshot
Long-range chromatin interactions in pathogenic gene expression control
inferred← citeshttps://doi.org/10.1080/21541264.2025.2570066openalex-snapshot
Perspective: divergent mRNA transcription machinery in Paramecium
inferred← citeshttps://doi.org/10.1080/23723556.2021.1986350openalex-snapshot
Chromatin state profiling reveals PRC2 inhibition as a therapeutic target in NRAS–mutant melanoma
inferred← citeshttps://doi.org/10.1093/bioinformatics/btz173openalex-snapshot
Stable H3K4me3 is associated with transcription initiation during early embryo development
inferred← citeshttps://doi.org/10.1093/jimmun/vkaf156openalex-snapshot
Diet-induced obesity induces oxidative stress and enhances H3K4me3 levels, driving nonresolving inflammation and myelopoiesis in hematopoietic stem and progenitor cells
inferred← citeshttps://doi.org/10.1093/nar/gkac1090openalex-snapshot
CHD6 promotes broad nucleosome eviction for transcriptional activation in prostate cancer cells
inferred← citeshttps://doi.org/10.1093/nar/gkad300openalex-snapshot
Low RNA stability signifies increased post-transcriptional regulation of cell identity genes
inferred← citeshttps://doi.org/10.1093/nar/gkad838openalex-snapshot
Low RNA stability signifies strong expression regulatability of tumor suppressors
inferred← citeshttps://doi.org/10.1093/nar/gkae498openalex-snapshot
Efficient activation of hundreds of LTR12C elements reveals cis-regulatory function determined by distinct epigenetic mechanisms
inferred← citeshttps://doi.org/10.1093/nar/gkaf431openalex-snapshot
SCIG: Machine learning uncovers cell identity genes in single cells by genetic sequence codes
inferred← citeshttps://doi.org/10.1093/nar/gkaf931openalex-snapshot
Transcription factor 4 maintains endothelial cell identity by inhibiting endothelial to mesenchymal transition
inferred← citeshttps://doi.org/10.1093/nar/gkag125openalex-snapshot
CFP1-mediated H3K4me3 broad domains control early B cell lineage fate determination
inferred← citeshttps://doi.org/10.1093/nar/gkx251openalex-snapshot
H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells
inferred← citeshttps://doi.org/10.1093/nar/gky063openalex-snapshot
Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC
inferred← citeshttps://doi.org/10.1093/nar/gky1203openalex-snapshot
Characterizing the nuclease accessibility of DNA in human cells to map higher order structures of chromatin
inferred← citeshttps://doi.org/10.1093/nar/gkz287openalex-snapshot
EpiAlign: an alignment-based bioinformatic tool for comparing chromatin state sequences
inferred← citeshttps://doi.org/10.1093/narcan/zcad063openalex-snapshot
TSCRE: a comprehensive database for tumor-specific cis-regulatory elements
inferred← citeshttps://doi.org/10.1093/procel/pwaf010openalex-snapshot
Setd2 overexpression rescues bivalent gene expression during SCNT-mediated ZGA
inferred← citeshttps://doi.org/10.1096/fj.201901818rropenalex-snapshot
Lineage specification and pluripotency revealed by transcriptome analysis from oocyte to blastocyst in pig
inferred← citeshttps://doi.org/10.1096/fj.202402382ropenalex-snapshot
Targeting MLL1 / WDR5 ‐Mediated Epigenetic Regulation Mitigates Peritoneal Fibrosis by Reducing p16 INK4a
inferred← citeshttps://doi.org/10.1096/fj.202500089ropenalex-snapshot
SMYD3 as an Epigenetic Regulator of Renal Tubular Cell Survival and Regeneration Following Acute Kidney Injury in Mice
inferred← citeshttps://doi.org/10.1097/moh.0000000000000346openalex-snapshot
Distinct functions of histone H3, lysine 4 methyltransferases in normal and malignant hematopoiesis
inferred← citeshttps://doi.org/10.1101/2020.11.10.375717openalex-snapshot
accuEnhancer: Accurate enhancer prediction by integration of multiple cell type data with deep learning
inferred← citeshttps://doi.org/10.1101/2021.07.16.452657openalex-snapshot
Global and Gene-specific Transcriptional Responses to Acute Stress
inferred← citeshttps://doi.org/10.1101/2022.08.02.502545openalex-snapshot
Flnc: Machine Learning Improves the Identification of Novel Full-length Long Noncoding RNAs from RNA Sequencing Data Without Transcriptional Initiation Profiles
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