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A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/archgenpsychiatry.2009.83openalex-snapshot
Genome-wide Association Study of Alcohol Dependence
inferredcites →https://doi.org/10.1002/hep.21023openalex-snapshot
Do alcohol-metabolizing enzyme gene polymorphisms increase the risk of alcoholism and alcoholic liver disease?
inferredcites →https://doi.org/10.1002/hep.24017openalex-snapshot
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians
inferredcites →https://doi.org/10.1002/hep.27242openalex-snapshot
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis
inferredcites →https://doi.org/10.1002/hep.27490openalex-snapshot
Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease
inferredcites →https://doi.org/10.1002/sim.1186openalex-snapshot
Quantifying heterogeneity in a meta‐analysis
inferredcites →https://doi.org/10.1007/s00439-011-1054-1openalex-snapshot
Artifact due to differential error when cases and controls are imputed from different platforms
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Simultaneous Genotype Calling and Haplotype Phasing Improves Genotype Accuracy and Reduces False-Positive Associations for Genome-wide Association Studies
inferredcites →https://doi.org/10.1016/j.ajhg.2013.10.021openalex-snapshot
Integrating GWASs and Human Protein Interaction Networks Identifies a Gene Subnetwork Underlying Alcohol Dependence
inferredcites →https://doi.org/10.1016/j.jhep.2013.03.007openalex-snapshot
Global burden of alcoholic liver diseases
inferredcites →https://doi.org/10.1016/j.jhep.2013.03.024openalex-snapshot
Marked 25-hydroxyvitamin D deficiency is associated with poor prognosis in patients with alcoholic liver disease
inferredcites →https://doi.org/10.1016/j.jhep.2014.06.006openalex-snapshot
A common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease
inferredcites →https://doi.org/10.1016/s0140-6736(95)91685-7openalex-snapshot
Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver
inferredcites →https://doi.org/10.1038/ajg.2015.137openalex-snapshot
PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease
inferredcites →https://doi.org/10.1038/nature05911openalex-snapshot
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
inferredcites →https://doi.org/10.1038/ncomms5309openalex-snapshot
TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease
inferredcites →https://doi.org/10.1038/ng.257openalex-snapshot
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
inferredcites →https://doi.org/10.1038/ng.2901openalex-snapshot
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease
inferredcites →https://doi.org/10.1038/ng.379openalex-snapshot
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
inferredcites →https://doi.org/10.1038/ng.488openalex-snapshot
Variant in PNPLA3 is associated with alcoholic liver disease
inferredcites →https://doi.org/10.1038/ng.728openalex-snapshot
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
inferredcites →https://doi.org/10.1038/ng.789openalex-snapshot
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis
inferredcites →https://doi.org/10.1038/ng1847openalex-snapshot
Principal components analysis corrects for stratification in genome-wide association studies
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A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease
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Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection
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Burden of liver disease in the United States: Summary of a workshop
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Early Liver Transplantation for Severe Alcoholic Hepatitis
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A genome-wide association study of alcohol dependence
inferredcites →https://doi.org/10.1074/jbc.m109.064501openalex-snapshot
A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
inferredcites →https://doi.org/10.1074/jbc.m303391200openalex-snapshot
Reverse Reaction of Lysophosphatidylinositol Acyltransferase
inferredcites →https://doi.org/10.1074/jbc.m806194200openalex-snapshot
Lysophospholipid Acyltransferases and Arachidonate Recycling in Human Neutrophils
inferredcites →https://doi.org/10.1093/bioinformatics/btq419openalex-snapshot
LocusZoom: regional visualization of genome-wide association scan results
inferredcites →https://doi.org/10.1093/hmg/ddu121openalex-snapshot
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells
inferredcites →https://doi.org/10.1111/adb.12141openalex-snapshot
Genetic variants in or nearADH1BandADH1Caffect susceptibility to alcohol dependence in a British and Irish population
inferredcites →https://doi.org/10.1111/apt.12890openalex-snapshot
Systematic review with meta‐analysis: the I148M variant of patatin‐like phospholipase domain‐containing 3 gene (PNPLA3) is significantly associated with alcoholic liver cirrhosis
inferredcites →https://doi.org/10.1111/j.1365-2036.2008.03831.xopenalex-snapshot
Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non‐invasive laboratory tests
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Evidence of Genetic Predisposition to Alcoholic Cirrhosis and Psychosis: Twin Concordances for Alcoholism and Its Biological End Points by Zygosity among Male Veterans
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Alcoholic Liver Disease: Pathologic, Pathogenetic and Clinical Aspects
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Genetic Predisposition to Organ‐Specific Endpoints of Alcoholism
inferredcites →https://doi.org/10.1111/j.1600-6143.2009.02869.xopenalex-snapshot
Liver Transplantation for Alcoholic Liver Disease in Europe: A Study from the ELTR (European Liver Transplant Registry)
inferredcites →https://doi.org/10.1371/journal.pgen.1000529openalex-snapshot
A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies
inferredcites →https://doi.org/10.1371/journal.pgen.1001324openalex-snapshot
Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits
inferredcites →https://doi.org/10.1371/journal.pgen.1002078openalex-snapshot
Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue
inferredcites →https://doi.org/10.1371/journal.pone.0097589openalex-snapshot
fcGENE: A Versatile Tool for Processing and Transforming SNP Datasets
inferredcites →https://doi.org/10.2119/molmed.2011.00149openalex-snapshot
Cannabinoid Receptor Type I Modulates Alcohol-Induced Liver Fibrosis
inferredcites →https://doi.org/10.2337/db11-0649openalex-snapshot
The l -α-Lysophosphatidylinositol/ GPR55 System and Its Potential Role in Human Obesity
inferredcites →https://doi.org/10.7326/0003-4819-150-3-200902030-00004openalex-snapshot
Immediate Listing for Liver Transplantation Versus Standard Care for Child–Pugh Stage B Alcoholic Cirrhosis
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Identification of Alcoholic Hepatitis-Related and Mesenchymal Stem Cell Therapy Target Genes
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Diagnosis and Treatment of Alcohol-Associated Liver Disease
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Hepatic Lipid Droplets in Liver Function and Disease
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Clinical Genomics of NAFLD
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Evidence for PTGER 4 , PSCA , and MBOAT 7 as risk genes for gastric cancer on the genome and transcriptome level
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Genetics in liver diseases: From diagnostics to precise therapy
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Are We Really Taking Care of Alcohol‐Related Liver Disease in Latin America?
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Is moderate alcohol use in nonalcoholic fatty liver disease good or bad? A critical review
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The membrane‐bound O‐acyltransferase domain‐containing 7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B
inferred← citeshttps://doi.org/10.1002/hep.29751openalex-snapshot
Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride
inferred← citeshttps://doi.org/10.1002/hep.29809openalex-snapshot
Khat chewing increases the risk for developing chronic liver disease
inferred← citeshttps://doi.org/10.1002/hep.30350openalex-snapshot
17‐Beta Hydroxysteroid Dehydrogenase 13 Is a Hepatic Retinol Dehydrogenase Associated With Histological Features of Nonalcoholic Fatty Liver Disease
inferred← citeshttps://doi.org/10.1002/hep.30473openalex-snapshot
Alcohol-related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study
inferred← citeshttps://doi.org/10.1002/hep.30623openalex-snapshot
A 17‐Beta‐Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease
inferred← citeshttps://doi.org/10.1002/hep.30799openalex-snapshot
High Risk of Fatty Liver Disease Amplifies the Alanine Transaminase–Lowering Effect of a HSD17B13 Variant
inferred← citeshttps://doi.org/10.1002/hep.30866openalex-snapshot
Diagnosis and Treatment of Alcohol‐Associated Liver Diseases: 2019 Practice Guidance From the American Association for the Study of Liver Diseases
inferred← citeshttps://doi.org/10.1002/hep.30996openalex-snapshot
Genetic Variation in HSD17B13 Reduces the Risk of Developing Cirrhosis and Hepatocellular Carcinoma in Alcohol Misusers
inferred← citeshttps://doi.org/10.1002/hep.31229openalex-snapshot
Genetic Pathways in Nonalcoholic Fatty Liver Disease: Insights From Systems Biology
inferred← citeshttps://doi.org/10.1002/hep.31394openalex-snapshot
Genetics of Hepatocellular Carcinoma: Approaches to Explore Molecular Diversity
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Hepatic Fat—Genetic Risk Score Predicts Hepatocellular Carcinoma in Patients With Cirrhotic HCV Treated With DAAs
inferred← citeshttps://doi.org/10.1002/hep.31517openalex-snapshot
17‐Beta Hydroxysteroid Dehydrogenase 13 Deficiency Does Not Protect Mice From Obesogenic Diet Injury
inferred← citeshttps://doi.org/10.1002/hep.31535openalex-snapshot
Genome‐wide Association Study and Meta‐analysis on Alcohol‐Associated Liver Cirrhosis Identifies Genetic Risk Factors
inferred← citeshttps://doi.org/10.1002/hep.32115openalex-snapshot
Genome‐wide association of individual vulnerability with alcohol‐associated liver disease: A Korean genome and epidemiology study
inferred← citeshttps://doi.org/10.1002/hep.32288openalex-snapshot
Vulnerability to alcohol‐associated liver disease: A tale of two systems
inferred← citeshttps://doi.org/10.1002/hep4.1123openalex-snapshot
Interaction between the patatin‐like phospholipase domain‐containing protein 3 genotype and coffee drinking and the risk for acute alcoholic hepatitis
inferred← citeshttps://doi.org/10.1002/hep4.1183openalex-snapshot
Patatin‐like phospholipase domain containing 3 variants differentially impact metabolic traits in individuals at high risk for cardiovascular events
inferred← citeshttps://doi.org/10.1002/hep4.1319openalex-snapshot
Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease
inferred← citeshttps://doi.org/10.1002/hep4.1751openalex-snapshot
Association of Genetic Risk Score With NAFLD in An Ethnically Diverse Cohort
inferred← citeshttps://doi.org/10.1002/hep4.1822openalex-snapshot
TM6SF2: A Novel Genetic Player in Nonalcoholic Fatty Liver and Cardiovascular Disease
inferred← citeshttps://doi.org/10.1002/hep4.1886openalex-snapshot
The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis
inferred← citeshttps://doi.org/10.1002/hep4.1903openalex-snapshot
Transcriptomic Analysis Reveals the Messenger RNAs Responsible for the Progression of Alcoholic Cirrhosis
inferred← citeshttps://doi.org/10.1002/ijc.31910openalex-snapshot
PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases
inferred← citeshttps://doi.org/10.1002/jgm.3001openalex-snapshot
Association of PNPLA3 rs738409 polymorphism with liver steatosis but not with cirrhosis in patients with HBV infection: Systematic review with meta‐analysis
inferred← citeshttps://doi.org/10.1002/lci2.47openalex-snapshot
Validation of the aMAP score to predict hepatocellular carcinoma development in a cohort of alcohol‐related cirrhosis patients
inferred← citeshttps://doi.org/10.1002/lci2.70006openalex-snapshot
An Insight into the Genetic Predisposition of Metabolic Dysfunction‐Associated Steatotic Liver Disease in Africa
inferred← citeshttps://doi.org/10.1002/lipd.12033openalex-snapshot
Noncholesterol Sterols as Surrogate Markers in Patients with Severe Alcoholic Hepatitis
inferred← citeshttps://doi.org/10.1002/mgg3.824openalex-snapshot
The roles of transmembrane 6 superfamily member 2 rs58542926 polymorphism in chronic liver disease: A meta‐analysis of 24,147 subjects
inferred← citeshttps://doi.org/10.1002/pmic.201900138openalex-snapshot
Specificity of Acyl Chain Composition of Phosphatidylinositols
inferred← citeshttps://doi.org/10.1007/978-1-4471-4715-2_8openalex-snapshot
Alcohol Induced Liver Disease
inferred← citeshttps://doi.org/10.1007/978-3-030-37173-9_3openalex-snapshot
Genes and NAFLD/NASH Progression
inferred← citeshttps://doi.org/10.1007/978-3-030-40542-7_27openalex-snapshot
Genetic Confounders of Liver Stiffness and Controlled Attenuation Parameter
inferred← citeshttps://doi.org/10.1007/978-3-030-50621-6_2openalex-snapshot
Biosynthetic Enzymes of Membrane Glycerophospholipid Diversity as Therapeutic Targets for Drug Development
inferred← citeshttps://doi.org/10.1007/978-3-031-08552-9_4openalex-snapshot
Lifestyle and Genetic Modifiers of Liver Disease Progression
inferred← citeshttps://doi.org/10.1007/978-3-031-32483-3_51openalex-snapshot
Modulation of Alcohol-Related Liver Disease by Obesity and Diabetes
inferred← citeshttps://doi.org/10.1007/978-3-031-32483-3_52openalex-snapshot
The Genetics of Alcohol-Related Liver Disease
inferred← citeshttps://doi.org/10.1007/978-3-031-32483-3_54openalex-snapshot
Alcoholic Fibrosis/Cirrhosis and Its Reversibility
inferred← citeshttps://doi.org/10.1007/978-3-319-95828-6_6openalex-snapshot
Mechanisms of Fibrogenesis in NASH
inferred← citeshttps://doi.org/10.1007/978-3-319-98788-0_12openalex-snapshot
Suppressed Fat Mobilization Due to PNPLA3 rs738409 -Associated Liver Damage in Heavy Drinkers: The Liver Damage Feedback Hypothesis
inferred← citeshttps://doi.org/10.1007/978-3-319-98890-0_12openalex-snapshot
Genetic Aspects of Non-alcoholic Fatty Liver Disease (NAFLD)
inferred← citeshttps://doi.org/10.1007/978-3-662-62484-5_8openalex-snapshot
Pathophysiologie: Genetik
inferred← citeshttps://doi.org/10.1007/978-3-662-63123-2_35openalex-snapshot
Disorders of Intracellular Triglyceride and Phospholipid Metabolism
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Genome Editing and Fatty Liver
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Liver Steatosis: From Lipotoxicity to Cellular Damage
inferred← citeshttps://doi.org/10.1007/s00018-020-03715-4openalex-snapshot
Integrating lipidomics and genomics: emerging tools to understand cardiovascular diseases
inferred← citeshttps://doi.org/10.1007/s00109-019-01836-3openalex-snapshot
The PNPLA3 I148M variant promotes lipid-induced hepatocyte secretion of CXC chemokines establishing a tumorigenic milieu
inferred← citeshttps://doi.org/10.1007/s00125-026-06761-yopenalex-snapshot
MASLD, diabetes and PMOS across the female life stages
inferred← citeshttps://doi.org/10.1007/s00535-018-01533-xopenalex-snapshot
Independent and additive effects of PNPLA3 and TM6SF2 polymorphisms on the development of non-B, non-C hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1007/s00535-024-02157-0openalex-snapshot
Immunological dynamics in MASH: from landscape analysis to therapeutic intervention
inferred← citeshttps://doi.org/10.1007/s10557-016-6644-7openalex-snapshot
Experimental Biology for the Identification of Causal Pathways in Atherosclerosis
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Coexistent Alcohol-Related Liver Disease and Alcohol-Related Pancreatitis: Analysis of a Large Health Care System Cohort
inferred← citeshttps://doi.org/10.1007/s10620-023-08104-yopenalex-snapshot
MBOAT7 rs641738 Variant Is Not Associated with an Increased Risk of Hepatocellular Carcinoma in a Latin American Cohort
inferred← citeshttps://doi.org/10.1007/s11033-023-09009-9openalex-snapshot
MBOAT7 expression is associated with disease progression in COVID-19 patients
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Nicht alkoholische (NAFLE) und alkoholische Lebererkrankung (ALE)
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Genetik metabolischer und viraler Lebererkrankungen
inferred← citeshttps://doi.org/10.1007/s11428-020-00647-2openalex-snapshot
Genetisches Risiko bei metabolischer Fettlebererkrankung
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Genetic Contribution to Non-alcoholic Fatty Liver Disease and Prognostic Implications
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Alcohol Consumption in Concomitant Liver Disease: How Much is Too Much?
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Genetic and Epigenetic Associations of NAFLD: Focus on Clinical Decision Making
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Overcoming Alcohol Addiction in Patients with Alcohol-Related Liver Disease
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Liver Diseases in Latin America: Current Status, Unmet Needs, and Opportunities for Improvement
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Association of fetuin B with markers of liver fibrosis in nonalcoholic fatty liver disease
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Recent Advances in Anticancer Activity of Novel Plant Extracts and Compounds from Curcuma longa in Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.1007/s12072-018-9889-3openalex-snapshot
Single-nucleotide rs738409 polymorphisms in the PNPLA3 gene are strongly associated with alcoholic liver disease in Han Chinese males
inferred← citeshttps://doi.org/10.1007/s12072-022-10331-wopenalex-snapshot
A rare genetic variant in the manganese transporter SLC30A10 and elevated liver enzymes in the general population
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Characteristics and long-term mortality of patients with non-MAFLD hepatic steatosis
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The contribution of genetics and epigenetics to MAFLD susceptibility
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Waist-to-height ratio as a practical indicator for screening pediatric metabolic dysfunction-associated steatotic liver disease in diverse populations and genetic backgrounds
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A study of genetic variants, genetic risk score and DNA methylation of PNPLA3 and TM6SF2 in alcohol liver cirrhosis
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Impact of differential detection of TM6SF2 rs58542926 mutation in circulating tumor DNA versus peripheral blood cells on hepatocellular carcinoma patients
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Prognostication in NAFLD: physiological bases, clinical indicators, and newer biomarkers
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Genetics of Polygenic Metabolic Liver Disease
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Molecular prognosis in liver cirrhosis
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Molecular Basis of Liver Disease
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PNPLA3 Variant p.I148M and Bariatric Surgery
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Molecular basis of liver disease
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Nonalcoholic fatty liver disease
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Molecular pathology of hepatocellular carcinoma
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Molecular and Genetics-Based Diagnostics
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Metabolic-associated fatty liver disease: epidemiology, natural history and diagnosis, current paradigm and definitions for MAFLD
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Alcohol-associated liver disease
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10.1016/b978-84-9113-949-2.00086-x
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Predictive risk markers in alcoholism
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Liver fibrogenesis: un update on established and emerging basic concepts
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An Update on IL-22 Therapies in Alcohol-Associated Liver Disease and Beyond
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The Patatin-Like Phospholipase Domain–Containing 3 148M Variant Exacerbates Alcohol-Induced Liver Injury and Tumorigenesis in Mice
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Alcohol-Associated Hepatocarcinogenesis
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Binge alcohol alters PNPLA3 levels in liver through epigenetic mechanism involving histone H3 acetylation
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Mechanisms, biomarkers and targets for therapy in alcohol-associated liver injury: From Genetics to nutrition: Summary of the ISBRA 2018 symposium
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Alcohol-related liver disease: Clinical practice guidelines by the Latin American Association for the Study of the Liver (ALEH)
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PNPLA3 rs738409 associates with alcoholic liver cirrhosis but not with serum levels of IL6, IL10, IL8 or CCL2 in the Russian population
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The burden of liver disease in Latin America
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Clinical and molecular implications of antipsychotics in MASLD
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The role of PNPLA3 in health and disease
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Cytosolic phospholipase A2 and lysophospholipid acyltransferases
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Group VIA phospholipase A2 deficiency in mice chronically fed with high-fat-diet attenuates hepatic steatosis by correcting a defect of phospholipid remodeling
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iPla2β deficiency in mice fed with MCD diet does not correct the defect of phospholipid remodeling but attenuates hepatocellular injury via an inhibition of lipid uptake genes
inferred← citeshttps://doi.org/10.1016/j.bbalip.2021.158891openalex-snapshot
LPIAT1/MBOAT7 contains a catalytic dyad transferring polyunsaturated fatty acids to lysophosphatidylinositol
inferred← citeshttps://doi.org/10.1016/j.bbalip.2023.159348openalex-snapshot
Characterization of lipid signatures in the plasma and insulin-sensitive tissues of the C57BL/6J mice fed on obesogenic diets
inferred← citeshttps://doi.org/10.1016/j.bbcan.2025.189290openalex-snapshot
Alpha-1 antitrypsin deficiency and primary liver cancers
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116241openalex-snapshot
The fatty acid omega hydroxylase genes (CYP4 family) in the progression of metabolic dysfunction-associated steatotic liver disease (MASLD): An RNA sequence database analysis and review
inferred← citeshttps://doi.org/10.1016/j.biochi.2023.08.012openalex-snapshot
Lysophospholipid acyltransferases orchestrate the compositional diversity of phospholipids
inferred← citeshttps://doi.org/10.1016/j.bpg.2017.09.003openalex-snapshot
Alcohol, smoking and the liver disease patient
inferred← citeshttps://doi.org/10.1016/j.cbi.2019.108918openalex-snapshot
The role of cytochrome P4502E1 in the pathogenesis of alcoholic liver disease and carcinogenesis
inferred← citeshttps://doi.org/10.1016/j.cell.2021.04.015openalex-snapshot
Mechanisms and disease consequences of nonalcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1016/j.cell.2023.03.014openalex-snapshot
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease
inferred← citeshttps://doi.org/10.1016/j.cgh.2016.05.041openalex-snapshot
Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis
inferred← citeshttps://doi.org/10.1016/j.cgh.2019.08.011openalex-snapshot
Association Between PNPLA3 rs738409 C>G Variant and Liver-Related Outcomes in Patients With Nonalcoholic Fatty Liver Disease
inferred← citeshttps://doi.org/10.1016/j.cgh.2020.08.054openalex-snapshot
Interaction Between Alcohol Consumption and PNPLA3 Variant in the Prevalence of Hepatic Steatosis in the US Population
inferred← citeshttps://doi.org/10.1016/j.cgh.2020.11.038openalex-snapshot
Metabolic and Genetic Risk Factors Are the Strongest Predictors of Severity of Alcohol-Related Liver Fibrosis
inferred← citeshttps://doi.org/10.1016/j.cgh.2022.05.020openalex-snapshot
Admixture Mapping in African Americans Identifies New Risk Loci for HCV-Related Cirrhosis
inferred← citeshttps://doi.org/10.1016/j.cgh.2024.03.045openalex-snapshot
Liver Fibrosis Assessed Via Noninvasive Tests Is Associated With Incident Heart Failure in a General Population Cohort
inferred← citeshttps://doi.org/10.1016/j.cgh.2024.05.052openalex-snapshot
Genetics of Metabolic Dysfunction-associated Steatotic Liver Disease: The State of the Art Update
inferred← citeshttps://doi.org/10.1016/j.cld.2017.08.008openalex-snapshot
Risk Factors for the Development of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis, Including Genetics
inferred← citeshttps://doi.org/10.1016/j.cld.2021.03.009openalex-snapshot
Epidemiology of Alcohol-Associated Liver Disease
inferred← citeshttps://doi.org/10.1016/j.cld.2021.03.010openalex-snapshot
Current and Future Biomarkers in Alcoholic Hepatitis
inferred← citeshttps://doi.org/10.1016/j.cld.2021.04.001openalex-snapshot
Genetic and Environmental Susceptibility to Alcoholic Hepatitis
inferred← citeshttps://doi.org/10.1016/j.cld.2023.01.006openalex-snapshot
Genetic Markers Predisposing to Nonalcoholic Steatohepatitis
inferred← citeshttps://doi.org/10.1016/j.cld.2024.06.007openalex-snapshot
Alcohol and Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.1016/j.clinre.2019.01.008openalex-snapshot
Meta-analysis of the association between MBOAT7 rs641738, TM6SF2 rs58542926 and nonalcoholic fatty liver disease susceptibility
inferred← citeshttps://doi.org/10.1016/j.clinre.2019.12.006openalex-snapshot
The MBOAT7 rs641738 variant is associated with an improved outcome in primary sclerosing cholangitis
inferred← citeshttps://doi.org/10.1016/j.clinre.2026.102909openalex-snapshot
Gene–environment interaction between heavy alcohol use and PNPLA3 rs738409 in incident cirrhosis: Evidence from a diverse U.S. cohort
inferred← citeshttps://doi.org/10.1016/j.clnu.2023.03.020openalex-snapshot
Influence of alcohol on newly developed metabolic dysfunction-associated fatty liver disease in both sexes: A longitudinal study
inferred← citeshttps://doi.org/10.1016/j.cmet.2017.08.002openalex-snapshot
Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases
inferred← citeshttps://doi.org/10.1016/j.cmet.2019.12.002openalex-snapshot
Leveraging Human Genetics to Identify Potential New Treatments for Fatty Liver Disease
inferred← citeshttps://doi.org/10.1016/j.cyto.2018.08.013openalex-snapshot
The role of IFN in the development of NAFLD and NASH
inferred← citeshttps://doi.org/10.1016/j.dld.2019.09.015openalex-snapshot
Risk of chemotherapy-associated liver injury (CALI) in PNPLA3 p.148M allele carriers: Preliminary results of a transient elastography-based study
inferred← citeshttps://doi.org/10.1016/j.dld.2021.06.015openalex-snapshot
PNPLA3 is the dominant SNP linked to liver disease severity at time of first referral to a tertiary center
inferred← citeshttps://doi.org/10.1016/j.dld.2023.02.012openalex-snapshot
The impact of transmembrane 6 superfamily 2 (TM6SF2) rs58542926 on liver-related events in patients with advanced chronic liver disease
inferred← citeshttps://doi.org/10.1016/j.ebiom.2020.102658openalex-snapshot
MBOAT7 Down-Regulation by Hyperinsulinemia Induces Fat Accumulation in Hepatocytes
inferred← citeshttps://doi.org/10.1016/j.ebiom.2020.102866openalex-snapshot
MBOAT7 down-regulation by genetic and environmental factors predisposes to MAFLD
inferred← citeshttps://doi.org/10.1016/j.eclinm.2023.102350openalex-snapshot
Effect of donor HSD17B13 genotype on patient survival after liver transplant: a retrospective cohort study
inferred← citeshttps://doi.org/10.1016/j.foodres.2022.111180openalex-snapshot
Sequentially fermented dealcoholized apple juice intervenes fatty liver induced by high-fat diets via modulation of intestinal flora and gene pathways
inferred← citeshttps://doi.org/10.1016/j.gastha.2024.100592openalex-snapshot
Racial Disparities of Alcohol-Associated Liver Disease and Its Complications in Hospitalized Patients With Alcohol Use Disorder
inferred← citeshttps://doi.org/10.1016/j.gastre.2019.09.003openalex-snapshot
Alcohol-related liver disease. Clinical practice guidelines. Consensus document sponsored by AEEH
inferred← citeshttps://doi.org/10.1016/j.gastrohep.2019.09.006openalex-snapshot
Enfermedad hepática por alcohol. Guías de práctica clínica. Documento de consenso auspiciado por la AEEH
inferred← citeshttps://doi.org/10.1016/j.gtc.2019.09.001openalex-snapshot
Genetic Risk Factors and Disease Modifiers of Nonalcoholic Steatohepatitis
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.101470openalex-snapshot
Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity
inferred← citeshttps://doi.org/10.1016/j.jbc.2024.107353openalex-snapshot
Biochemical and functional characterization of the p.A165T missense variant of mitochondrial amidoxime-reducing component 1
inferred← citeshttps://doi.org/10.1016/j.jceh.2022.05.004openalex-snapshot
Pathogenesis of Alcohol-Associated Liver Disease
inferred← citeshttps://doi.org/10.1016/j.jceh.2022.07.246openalex-snapshot
Emerging Biomarkers in Alcohol-associated Hepatitis
inferred← citeshttps://doi.org/10.1016/j.jceh.2024.102446openalex-snapshot
Global Epidemiology of Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.11.007openalex-snapshot
TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.12.008openalex-snapshot
Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats
inferred← citeshttps://doi.org/10.1016/j.jep.2020.112813openalex-snapshot
Lignans from Schisandra chinensis ameliorate alcohol and CCl4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR
inferred← citeshttps://doi.org/10.1016/j.jhep.2016.03.011openalex-snapshot
PNPLA3 gene in liver diseases
inferred← citeshttps://doi.org/10.1016/j.jhep.2016.07.045openalex-snapshot
The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans
inferred← citeshttps://doi.org/10.1016/j.jhep.2016.08.011openalex-snapshot
The genetics of alcohol dependence and alcohol-related liver disease
inferred← citeshttps://doi.org/10.1016/j.jhep.2017.01.018openalex-snapshot
Homozygosity for rs738409:G in PNPLA3 is associated with increased mortality following an episode of severe alcoholic hepatitis
inferred← citeshttps://doi.org/10.1016/j.jhep.2017.04.001openalex-snapshot
Evidence for a role of genetics in alcoholic hepatitis: Data from the STOPAH randomized controlled trial
inferred← citeshttps://doi.org/10.1016/j.jhep.2017.09.003openalex-snapshot
Genetics and epigenetics of NAFLD and NASH: Clinical impact
inferred← citeshttps://doi.org/10.1016/j.jhep.2017.11.006openalex-snapshot
The bidirectional impacts of alcohol consumption and the metabolic syndrome: Cofactors for progressive fatty liver disease
inferred← citeshttps://doi.org/10.1016/j.jhep.2017.11.038openalex-snapshot
The PNPLA3 SNP rs738409:G allele is associated with increased liver disease-associated mortality but reduced overall mortality in a population-based cohort
inferred← citeshttps://doi.org/10.1016/j.jhep.2018.10.041openalex-snapshot
Alcohol-related liver disease: Areas of consensus, unmet needs and opportunities for further study
inferred← citeshttps://doi.org/10.1016/j.jhep.2018.12.003openalex-snapshot
Fibrosis and alcohol-related liver disease
inferred← citeshttps://doi.org/10.1016/j.jhep.2020.02.020openalex-snapshot
Update on NAFLD genetics: From new variants to the clinic
inferred← citeshttps://doi.org/10.1016/j.jhep.2020.08.027openalex-snapshot
rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis
inferred← citeshttps://doi.org/10.1016/j.jhep.2021.01.045openalex-snapshot
Diagnosis and management of secondary causes of steatohepatitis
inferred← citeshttps://doi.org/10.1016/j.jhep.2021.02.012openalex-snapshot
Targeting cell-intrinsic metabolism for antifibrotic therapy
inferred← citeshttps://doi.org/10.1016/j.jhep.2021.10.005openalex-snapshot
A genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers
inferred← citeshttps://doi.org/10.1016/j.jhep.2021.12.024openalex-snapshot
Metabolic and genetic contributions to NAFLD: Really distinct and homogeneous?
inferred← citeshttps://doi.org/10.1016/j.jhep.2022.03.026openalex-snapshot
Impact of non-invasive biomarkers on hepatology practice: Past, present and future
inferred← citeshttps://doi.org/10.1016/j.jhep.2022.04.008openalex-snapshot
A good step toward low-cost prognostication of liver-related outcome awaits more validation
inferred← citeshttps://doi.org/10.1016/j.jhep.2022.04.040openalex-snapshot
Ethyl glucuronide in hair detects a high rate of harmful alcohol consumption in presumed non-alcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1016/j.jhep.2022.11.003openalex-snapshot
Integrating genetic variants into clinical models for hepatocellular carcinoma risk stratification in cirrhosis
inferred← citeshttps://doi.org/10.1016/j.jhep.2023.03.038openalex-snapshot
An integrated view of anti-inflammatory and antifibrotic targets for the treatment of NASH
inferred← citeshttps://doi.org/10.1016/j.jhep.2023.05.007openalex-snapshot
Therapeutic opportunities for the treatment of NASH with genetically validated targets
inferred← citeshttps://doi.org/10.1016/j.jhep.2024.01.032openalex-snapshot
Exploring the impact of the PNPLA3 I148M variant on primary human hepatic stellate cells using 3D extracellular matrix models
inferred← citeshttps://doi.org/10.1016/j.jhep.2024.03.035openalex-snapshot
Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases
inferred← citeshttps://doi.org/10.1016/j.jhep.2024.12.030openalex-snapshot
Differences between hepatocellular carcinoma caused by alcohol and other aetiologies
inferred← citeshttps://doi.org/10.1016/j.jhep.2024.12.046openalex-snapshot
AZD2693, a PNPLA3 antisense oligonucleotide, for the treatment of MASH in 148M homozygous participants: Two randomized phase I trials
inferred← citeshttps://doi.org/10.1016/j.jhepr.2020.100101openalex-snapshot
Combined alcoholic and non-alcoholic steatohepatitis
inferred← citeshttps://doi.org/10.1016/j.jhepr.2021.100262openalex-snapshot
Inborn and acquired risk factors for severe liver disease in Europeans with type 2 diabetes from the UK Biobank
inferred← citeshttps://doi.org/10.1016/j.jhepr.2021.100284openalex-snapshot
Genetic predisposition similarities between NASH and ASH: Identification of new therapeutic targets
inferred← citeshttps://doi.org/10.1016/j.jhepr.2022.100466openalex-snapshot
Epigenetics of alcohol-related liver diseases
inferred← citeshttps://doi.org/10.1016/j.jhepr.2023.100684openalex-snapshot
High producer variant of lipoprotein lipase may protect from hepatocellular carcinoma in alcohol-associated cirrhosis
inferred← citeshttps://doi.org/10.1016/j.jhepr.2024.101243openalex-snapshot
Deep metabolic phenotyping of humans with protein-altering variants in TM6SF2 using a genome-first approach
inferred← citeshttps://doi.org/10.1016/j.jlr.2021.100104openalex-snapshot
Nonalcoholic fatty liver disease stratification by liver lipidomics
inferred← citeshttps://doi.org/10.1016/j.jlr.2022.100234openalex-snapshot
Membrane-bound O-acyltransferase 7 (MBOAT7)-driven phosphatidylinositol remodeling in advanced liver disease
inferred← citeshttps://doi.org/10.1016/j.jlr.2023.100349openalex-snapshot
MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis
inferred← citeshttps://doi.org/10.1016/j.jlr.2024.100514openalex-snapshot
Evaluation of antisense oligonucleotide therapy targeting Hsd17b13 in a fibrosis mice model
inferred← citeshttps://doi.org/10.1016/j.jlr.2025.100898openalex-snapshot
Advanced alcoholic liver disease driven by a proferroptotic diet
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2022.109081openalex-snapshot
The PNPLA3 variant I148M reveals protective effects toward hepatocellular carcinoma in mice via restoration of omega-3 polyunsaturated fats
inferred← citeshttps://doi.org/10.1016/j.jsb.2019.04.006openalex-snapshot
MBOAT7 is anchored to endomembranes by six transmembrane domains
inferred← citeshttps://doi.org/10.1016/j.jtauto.2019.100017openalex-snapshot
The complement system in liver diseases: Evidence-based approach and therapeutic options
inferred← citeshttps://doi.org/10.1016/j.jtauto.2024.100243openalex-snapshot
PNPLA3 I148 M genetic variant in autoimmune hepatitis characterises advanced disease at diagnosis and reduced survival free of cirrhotic events and liver-related mortality
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