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Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/aja.1002040211openalex-snapshot
Developmental expression of a type II collagen/β‐galactosidase fusion gene in transgenic mice
inferredcites →https://doi.org/10.1002/jbmr.5650090603openalex-snapshot
Opposite effects of osteogenic protein and transforming growth factor β on chondrogenesis in cultured long bone rudiments
inferredcites →https://doi.org/10.1006/abbi.2000.1820openalex-snapshot
Mechanical and Physicochemical Regulation of the Action of Insulin-Like Growth Factor-I on Articular Cartilage
inferredcites →https://doi.org/10.1006/bbrc.1993.2112openalex-snapshot
Nonradioisotopic Quantitative RT-PCR to Detect Changes in mRNA Levels during Early Mouse Embryo Development
inferredcites →https://doi.org/10.1006/geno.1994.1633openalex-snapshot
Molecular Cloning and Chromosomal Assignment of the Mouse C-Type Natriuretic Peptide (CNP) Gene (Nppc): Comparison with the Human CNP Gene (NPPC)
inferredcites →https://doi.org/10.1007/978-94-009-0083-7_9openalex-snapshot
Molecular biology and biochemistry of the natriuretic peptide system
inferredcites →https://doi.org/10.1007/s002470050165openalex-snapshot
Short-limb skeletal dysplasias and craniosynostosis: what do they have in common?
inferredcites →https://doi.org/10.1016/0014-5793(90)80544-sopenalex-snapshot
Cloning and sequence analysis of a cDNA encoding a precursor for rat C‐type natriuretic peptide (CNP)
inferredcites →https://doi.org/10.1016/0092-8674(94)90302-6openalex-snapshot
Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
inferredcites →https://doi.org/10.1016/b978-0-12-571146-3.50008-0openalex-snapshot
Guanylate Cyclase Receptor Family
inferredcites →https://doi.org/10.1016/s0092-8674(00)81069-7openalex-snapshot
Fibroblast Growth Factor Receptor 3 Is a Negative Regulator of Bone Growth
inferredcites →https://doi.org/10.1016/s1359-6101(00)00014-9openalex-snapshot
FGF signals for cell proliferation and migration through different pathways
inferredcites →https://doi.org/10.1016/s1534-5807(02)00261-7openalex-snapshot
Interaction of FGF, Ihh/Pthlh, and BMP Signaling Integrates Chondrocyte Proliferation and Hypertrophic Differentiation
inferredcites →https://doi.org/10.1038/ng0496-390openalex-snapshot
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
inferredcites →https://doi.org/10.1073/pnas.071389098openalex-snapshot
Dwarfism and early death in mice lacking C-type natriuretic peptide
inferredcites →https://doi.org/10.1073/pnas.92.17.7686openalex-snapshot
A synthetic inhibitor of the mitogen-activated protein kinase cascade.
inferredcites →https://doi.org/10.1073/pnas.95.5.2337openalex-snapshot
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
inferredcites →https://doi.org/10.1073/pnas.96.13.7403openalex-snapshot
The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system
inferredcites →https://doi.org/10.1073/pnas.96.18.10278openalex-snapshot
Three new allelic mouse mutations that cause skeletal overgrowth involve the natriuretic peptide receptor C gene ( Npr3 )
inferredcites →https://doi.org/10.1073/pnas.97.3.1113openalex-snapshot
Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway
inferredcites →https://doi.org/10.1074/jbc.273.19.11695openalex-snapshot
Natriuretic Peptide Regulation of Endochondral Ossification
inferredcites →https://doi.org/10.1074/jbc.274.7.4293openalex-snapshot
Reciprocal Antagonism Coordinates C-type Natriuretic Peptide and Mitogen-signaling Pathways in Fibroblasts
inferredcites →https://doi.org/10.1074/jbc.m110608200openalex-snapshot
Maintenance of Differentiated Phenotype of Articular Chondrocytes by Protein Kinase C and Extracellular Signal-regulated Protein Kinase
inferredcites →https://doi.org/10.1083/jcb.133.2.457openalex-snapshot
Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor.
inferredcites →https://doi.org/10.1083/jcb.200105052openalex-snapshot
Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures
inferredcites →https://doi.org/10.1093/nar/20.18.4939openalex-snapshot
Quantification of mRNA by non-radioactive RT-PCR and CCD imaging system
inferredcites →https://doi.org/10.1097/00004872-199210000-00002openalex-snapshot
Molecular biology and biochemistry of the natriuretic peptide system. II: Natriuretic peptide receptors
inferredcites →https://doi.org/10.1101/gad.13.11.1361openalex-snapshot
FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway
inferredcites →https://doi.org/10.1126/science.274.5295.2082openalex-snapshot
Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-Dependent Protein Kinase II
inferredcites →https://doi.org/10.1126/science.2823385openalex-snapshot
Physiological Role of Silent Receptors of Atrial Natriuretic Factor
inferredcites →https://doi.org/10.1136/jmg.16.2.140openalex-snapshot
Achondroplasia and hypochondroplasia. Comments on frequency, mutation rate, and radiological features in skull and spine.
inferredcites →https://doi.org/10.1159/000244257openalex-snapshot
Insulin-Like Growth Factor 1 and Parathyroid Hormone Effects on the Growth of Fetal Rat Metatarsal Bones Cultured in Serum-Free Medium
inferredcites →https://doi.org/10.1203/00006450-200002000-00007openalex-snapshot
Regulation of Fetal Rat Bone Growth by C-Type Natriuretic Peptide and cGMP
inferredcites →https://doi.org/10.1210/endo.141.10.7692openalex-snapshot
Genetic Models Reveal That Brain Natriuretic Peptide Can Signal through Different Tissue-Specific Receptor-Mediated Pathways1
inferredcites →https://doi.org/10.1242/dev.125.24.4977openalex-snapshot
Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3
inferredcites →https://doi.org/10.1242/dev.128.11.2119openalex-snapshot
STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2
inferredcites →https://doi.org/10.1515/jpem.2001.14.1.17openalex-snapshot
Present Status of the Use of Growth Hormone in Short Children with Bone Diseases (Diseases of the Skeleton)
inferredcites →https://doi.org/10.1530/acta.0.1240602openalex-snapshot
Longitudinal bone growth in vitro: effects of insulin-like growth factor I and growth hormone
inferredcites →https://doi.org/10.1530/eje.0.1380275openalex-snapshot
Effect of growth hormone therapy in children with achondroplasia: growth pattern, hypothalamic-pituitary function, and genotype
inferredcites →https://doi.org/10.1681/asn.v12122652openalex-snapshot
Overexpression of Brain Natriuretic Peptide in Mice Ameliorates Immune-Mediated Renal Injury
inferredcites →https://doi.org/10.2106/00004623-199806000-00003openalex-snapshot
Distraction Osteogenesis of the Lower Extremity with Use of Monolateral External Fixation. A Study of Two Hundred and Sixty-one Femora and Tibiae*
inferredcites →https://doi.org/10.2106/00004623-199905000-00004openalex-snapshot
Distraction Osteogenesis for Lengthening of the Tibia in Patients Who Have Limb-Length Discrepancy or Short Stature*
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4488940openalex-extracted
Once-Weekly TransCon CNP in Children with Achondroplasia (ACcomplisH): A Phase 2, Multicentre, Randomised, Double-Blind, Placebo-Controlled, Dose-Escalation Trial
inferred← citeshttps://doi.org/10.1002/9780470015902.a0024296openalex-snapshot
Molecular Genetics of Achondroplasia
inferred← citeshttps://doi.org/10.1002/ajmg.a.31029openalex-snapshot
Recent milestones in achondroplasia research
inferred← citeshttps://doi.org/10.1002/ajmg.a.33188openalex-snapshot
Review of the recently defined molecular mechanisms underlying thanatophoric dysplasia and their potential therapeutic implications for achondroplasia
inferred← citeshttps://doi.org/10.1002/ajmg.a.37463openalex-snapshot
Acromesomelic dysplasia, type maroteaux caused by novel loss‐of‐function mutations of the NPR2 gene: Three case reports
inferred← citeshttps://doi.org/10.1002/ajmg.a.37734openalex-snapshot
Emerging targeted drug therapies in skeletal dysplasias
inferred← citeshttps://doi.org/10.1002/ajmg.a.63525openalex-snapshot
Radiological characteristics of skeletal growth in neonates and infants with achondroplasia
inferred← citeshttps://doi.org/10.1002/art.38199openalex-snapshot
Protective Effects of C‐Type Natriuretic Peptide on Linear Growth and Articular Cartilage Integrity in a Mouse Model of Inflammatory Arthritis
inferred← citeshttps://doi.org/10.1002/bdrc.20126openalex-snapshot
Regulation of cartilage formation and maturation by mitogen‐activated protein kinase signaling
inferred← citeshttps://doi.org/10.1002/bdrc.21060openalex-snapshot
The chondrocytic journey in endochondral bone growth and skeletal dysplasia
inferred← citeshttps://doi.org/10.1002/bip.21336openalex-snapshot
C‐type natriuretic peptide: Structural studies, fragment synthesis, and preliminary biological evaluation in human osteosarcoma cell lines
inferred← citeshttps://doi.org/10.1002/dvdy.24479openalex-snapshot
Achondroplasia: Development, pathogenesis, and therapy
inferred← citeshttps://doi.org/10.1002/humu.20511openalex-snapshot
Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation
inferred← citeshttps://doi.org/10.1002/humu.20611openalex-snapshot
A cluster of translocation breakpoints in 2q37 is associated with overexpression of NPPC in patients with a similar overgrowth phenotype
inferred← citeshttps://doi.org/10.1002/humu.21636openalex-snapshot
Sixteen years and counting: The current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias
inferred← citeshttps://doi.org/10.1002/humu.22773openalex-snapshot
Heterozygous Mutations in Natriuretic Peptide Receptor-B (NPR2) Gene as a Cause of Short Stature
inferred← citeshttps://doi.org/10.1002/jcb.20316openalex-snapshot
Stat1-mediated cytoplasmic attenuation in osteoimmunology
inferred← citeshttps://doi.org/10.1002/jcb.21448openalex-snapshot
The receptor attributable to C‐type natriuretic peptide‐induced differentiation of osteoblasts is switched from type B‐ to type C‐natriuretic peptide receptor with aging
inferred← citeshttps://doi.org/10.1002/jcb.22629openalex-snapshot
FGFs in endochondral skeletal development
inferred← citeshttps://doi.org/10.1002/jcp.20111openalex-snapshot
Cell‐cycle control and the cartilage growth plate
inferred← citeshttps://doi.org/10.1002/jcp.20620openalex-snapshot
Downregulation of Akt activity contributes to the growth arrest induced by FGF in chondrocytes
inferred← citeshttps://doi.org/10.1002/jcp.24083openalex-snapshot
Role of FGFs/FGFRs in skeletal development and bone regeneration
inferred← citeshttps://doi.org/10.1002/jor.21262openalex-snapshot
Genetic inactivation of ERK1 and ERK2 in chondrocytes promotes bone growth and enlarges the spinal canal
inferred← citeshttps://doi.org/10.1002/med.21388openalex-snapshot
Short Anabolic Peptides for Bone Growth
inferred← citeshttps://doi.org/10.1002/mgg3.1146openalex-snapshot
Role of NPR2 mutation in idiopathic short stature: Identification of two novel mutations
inferred← citeshttps://doi.org/10.1002/mrd.22114openalex-snapshot
CNP/NPR2 signaling maintains oocyte meiotic arrest in early antral follicles and is suppressed by EGFR‐mediated signaling in preovulatory follicles
inferred← citeshttps://doi.org/10.1002/wdev.176openalex-snapshot
The Fibroblast Growth Factor signaling pathway
inferred← citeshttps://doi.org/10.1007/3-540-28782-5_20openalex-snapshot
Regulation der Chondrozytendifferenzierung in der Wachstumsfuge: Parakrine Signalsysteme
inferred← citeshttps://doi.org/10.1007/978-1-0716-1028-2_1openalex-snapshot
Overview of Skeletal Development
inferred← citeshttps://doi.org/10.1007/978-1-4419-1795-9_166openalex-snapshot
C-Type Natriuretic Peptide (CNP) and Postnatal Linear Growth
inferred← citeshttps://doi.org/10.1007/978-1-4419-1795-9_168openalex-snapshot
The Role of Osteocrin and Its Interaction with the Natriuretic System in Bone Growth
inferred← citeshttps://doi.org/10.1007/978-1-62703-459-3_2openalex-snapshot
cGMP-Dependent Protein Kinases (cGK)
inferred← citeshttps://doi.org/10.1007/978-1-62703-989-5_1openalex-snapshot
Overview of Skeletal Development
inferred← citeshttps://doi.org/10.1007/978-1-84882-822-3_6openalex-snapshot
FGF/FGFR Signaling in Skeletal Dysplasias
inferred← citeshttps://doi.org/10.1007/978-2-8178-0196-4_2openalex-snapshot
Mécanismes moléculaires impliqués en aval du récepteur de l’hormone de croissance
inferred← citeshttps://doi.org/10.1007/978-3-031-70835-0_8openalex-snapshot
FGF Signaling: A Key Pathway During Skeletal Development
inferred← citeshttps://doi.org/10.1007/978-3-319-29568-8_8openalex-snapshot
Molecular Control of Cartilage Differentiation
inferred← citeshttps://doi.org/10.1007/978-3-540-68964-5_15openalex-snapshot
Natriuretic Peptides: Their Structures, Receptors, Physiologic Functions and Therapeutic Applications
inferred← citeshttps://doi.org/10.1007/978-3-540-68964-5_8openalex-snapshot
cGMP Regulated Protein Kinases (cGK)
inferred← citeshttps://doi.org/10.1007/978-3-642-38664-0_19openalex-snapshot
Vasoactive Peptides and the Pathogenesis of Pulmonary Hypertension: Role and Potential Therapeutic Application
inferred← citeshttps://doi.org/10.1007/978-4-431-55651-0openalex-snapshot
Innovative Medicine: Basic Research and Development
inferred← citeshttps://doi.org/10.1007/978-4-431-55651-0_15openalex-snapshot
Translational Research of the Activation of the C-Type Natriuretic Peptide (CNP)-Guanylyl Cyclase-B Pathway for Skeletal Dysplasia
inferred← citeshttps://doi.org/10.1007/s00018-009-8716-3openalex-snapshot
Osteocrin – Beyond just another bone protein?
inferred← citeshttps://doi.org/10.1007/s00018-013-1346-9openalex-snapshot
Regulatory mechanisms for the development of growth plate cartilage
inferred← citeshttps://doi.org/10.1007/s00109-009-0487-7openalex-snapshot
Kyoto University graduate school of medicine: tradition and modernity harmonized
inferred← citeshttps://doi.org/10.1007/s00109-009-0515-7openalex-snapshot
Translational research of novel hormones: lessons from animal models and rare human diseases for common human diseases
inferred← citeshttps://doi.org/10.1007/s00109-010-0641-2openalex-snapshot
NPR-C: a component of the natriuretic peptide family with implications in human diseases
inferred← citeshttps://doi.org/10.1007/s00109-017-1602-9openalex-snapshot
Molecular therapeutic strategies for FGFR3 gene-related skeletal dysplasia
inferred← citeshttps://doi.org/10.1007/s00125-006-0352-yopenalex-snapshot
Transgenic overexpression of brain natriuretic peptide prevents the progression of diabetic nephropathy in mice
inferred← citeshttps://doi.org/10.1007/s00223-011-9567-0openalex-snapshot
Skeletal Analysis of the Long Bone Abnormality (lbab/lbab) Mouse, A Novel Chondrodysplastic C-Type Natriuretic Peptide Mutant
inferred← citeshttps://doi.org/10.1007/s00223-022-00966-0openalex-snapshot
Collagen X Marker Levels are Decreased in Individuals with Achondroplasia
inferred← citeshttps://doi.org/10.1007/s00223-022-01014-7openalex-snapshot
Guanylyl Cyclase-B Dependent Bone Formation in Mice is Associated with Youth, Increased Osteoblasts, and Decreased Osteoclasts
inferred← citeshttps://doi.org/10.1007/s00429-011-0313-1openalex-snapshot
Mapping of NPR-B immunoreactivity in the brainstem of Macaca fascicularis
inferred← citeshttps://doi.org/10.1007/s00431-023-05263-yopenalex-snapshot
Novel therapeutic perspectives in Noonan syndrome and RASopathies
inferred← citeshttps://doi.org/10.1007/s00431-024-05949-xopenalex-snapshot
Investigation of serum C-type natriuretic peptide concentration at diagnosis and remission in pediatric osteosarcomas
inferred← citeshttps://doi.org/10.1007/s00441-008-0607-7openalex-snapshot
Differential regulation of cellular maturation in chondrocytes and osteoblasts by glycine
inferred← citeshttps://doi.org/10.1007/s00774-004-0598-8openalex-snapshot
Mutation in cGMP-dependent protein kinase II causes dwarfism in a rat mutant KMI through uncoupling of proliferation and differentiation of chondrocytes
inferred← citeshttps://doi.org/10.1007/s00774-008-0009-7openalex-snapshot
FGFR3-related dwarfism and cell signaling
inferred← citeshttps://doi.org/10.1007/s00774-010-0199-7openalex-snapshot
Coordination of chondrogenesis and osteogenesis by hypertrophic chondrocytes in endochondral bone development
inferred← citeshttps://doi.org/10.1007/s10165-005-0436-4openalex-snapshot
Involvement of cyclic guanosine monophosphate-dependent protein kinase II in chondrocyte hypertrophy during endochondral ossification
inferred← citeshttps://doi.org/10.1007/s10354-020-00741-6openalex-snapshot
New developments in the management of achondroplasia
inferred← citeshttps://doi.org/10.1007/s10815-021-02118-zopenalex-snapshot
Improved maturation competence of ovarian tissue oocytes using a biphasic in vitro maturation system for patients with gynecological malignancy: a study on sibling oocytes
inferred← citeshttps://doi.org/10.1007/s11010-009-0326-8openalex-snapshot
Central role of guanylyl cyclase in natriuretic peptide signaling in hypertension and metabolic syndrome
inferred← citeshttps://doi.org/10.1007/s11095-015-1636-zopenalex-snapshot
Human Monoclonal Antibody Fragments Targeting Matrilin-3 in Growth Plate Cartilage
inferred← citeshttps://doi.org/10.1007/s11302-011-9234-yopenalex-snapshot
Effects of diadenosine tetraphosphate on FGF9-induced chloride flux changes in achondroplastic chondrocytes
inferred← citeshttps://doi.org/10.1007/s11914-017-0347-2openalex-snapshot
Current Care and Investigational Therapies in Achondroplasia
inferred← citeshttps://doi.org/10.1007/s11914-017-0392-xopenalex-snapshot
Skeletal Dysplasias: What Every Bone Health Clinician Needs to Know
inferred← citeshttps://doi.org/10.1007/s12020-020-02362-wopenalex-snapshot
Growth plate gene involment and isolated short stature
inferred← citeshttps://doi.org/10.1007/s12264-024-01259-2openalex-snapshot
The Principle of Cortical Development and Evolution
inferred← citeshttps://doi.org/10.1007/s13258-020-00955-3openalex-snapshot
A novel nonsense mutation in NPR2 gene causing Acromesomelic dysplasia, type Maroteaux in a consanguineous family in Southern Punjab (Pakistan)
inferred← citeshttps://doi.org/10.1007/s40262-021-01059-1openalex-snapshot
Pharmacokinetics and Exposure–Response of Vosoritide in Children with Achondroplasia
inferred← citeshttps://doi.org/10.1007/s42000-025-00742-3openalex-snapshot
C-type natriuretic peptide as mediator of growth in the absence of growth hormone: Unraveling the mystery of the growth without GH syndrome
inferred← citeshttps://doi.org/10.1016/b978-0-12-373884-4.00065-3openalex-snapshot
Fibroblast Growth Factor (FGF) and FGF Receptor Families in Bone
inferred← citeshttps://doi.org/10.1016/b978-0-12-375098-3.50011-1openalex-snapshot
Development of the Skeleton
inferred← citeshttps://doi.org/10.1016/b978-0-12-415853-5.00006-6openalex-snapshot
Development of the Skeleton
inferred← citeshttps://doi.org/10.1016/b978-0-12-813073-5.00003-4openalex-snapshot
Development of the skeleton
inferred← citeshttps://doi.org/10.1016/b978-0-12-814841-9.00045-2openalex-snapshot
Fibroblast growth factor (FGF) and FGF receptor families in bone
inferred← citeshttps://doi.org/10.1016/b978-0-12-820472-6.00086-4openalex-snapshot
Endocrinology of Bone and Growth Disorders
inferred← citeshttps://doi.org/10.1016/b978-0-323-18907-1.00060-3openalex-snapshot
Bone Development and Remodeling
inferred← citeshttps://doi.org/10.1016/b978-0-323-31696-5.00105-4openalex-snapshot
Heritable Diseases of Connective Tissue
inferred← citeshttps://doi.org/10.1016/b978-012370544-0.50012-4openalex-snapshot
Development of the Skeleton
inferred← citeshttps://doi.org/10.1016/b978-1-4160-3264-9.50016-1openalex-snapshot
THE FETAL MUSCULOSKELETAL SYSTEM
inferred← citeshttps://doi.org/10.1016/b978-1-4160-5583-9.00059-9openalex-snapshot
Bone Development and Remodeling
inferred← citeshttps://doi.org/10.1016/b978-1-4160-5583-9.00111-8openalex-snapshot
Hormones of the Cardiovascular System
inferred← citeshttps://doi.org/10.1016/b978-1-4377-1738-9.00105-5openalex-snapshot
Heritable Diseases of Connective Tissue
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2018.11.020openalex-snapshot
Fibroblast growth factors in skeletal development
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2019.02.002openalex-snapshot
Mechanistic insights into skeletal development gained from genetic disorders
inferred← citeshttps://doi.org/10.1016/bs.vh.2017.06.002openalex-snapshot
Thyroid Hormone and Skeletal Development
inferred← citeshttps://doi.org/10.1016/j.ajhg.2012.10.014openalex-snapshot
Evaluation of the Therapeutic Potential of a CNP Analog in a Fgfr3 Mouse Model Recapitulating Achondroplasia
inferred← citeshttps://doi.org/10.1016/j.ajoms.2016.07.007openalex-snapshot
A novel therapeutic strategy for midfacial hypoplasia using the CNP/GC-B system
inferred← citeshttps://doi.org/10.1016/j.ando.2021.11.006openalex-snapshot
The heart, an endocrine gland: Natriuretic peptides
inferred← citeshttps://doi.org/10.1016/j.bbrc.2004.11.068openalex-snapshot
Molecular mechanisms of endochondral bone development
inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.08.139openalex-snapshot
Hypomorphic mutation in mouse Nppc gene causes retarded bone growth due to impaired endochondral ossification
inferred← citeshttps://doi.org/10.1016/j.bbrc.2011.03.009openalex-snapshot
A guanosine 3′,5′-cyclic monophosphate (cGMP) reporter system based on the G-kinase/CREB/CRE signal transduction pathway
inferred← citeshttps://doi.org/10.1016/j.bbrc.2012.08.077openalex-snapshot
A new method for establishing stable cell lines and its use for large-scale production of human guanylyl cyclase-B receptor and of the extracellular domain
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.01.001openalex-snapshot
Type II cGMP-dependent protein kinase negatively regulates fibroblast growth factor signaling by phosphorylating Raf-1 at serine 43 in rat chondrosarcoma cells
inferred← citeshttps://doi.org/10.1016/j.bcp.2007.04.023openalex-snapshot
Effect of diadenosine polyphosphates in achondroplasic chondrocytes: Inhibitory effect of Ap4A on FGF9 induced MAPK cascade
inferred← citeshttps://doi.org/10.1016/j.bone.2005.03.006openalex-snapshot
Complementary antagonistic actions between C-type natriuretic peptide and the MAPK pathway through FGFR-3 in ATDC5 cells
inferred← citeshttps://doi.org/10.1016/j.bone.2010.03.021openalex-snapshot
FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence
inferred← citeshttps://doi.org/10.1016/j.bone.2015.03.016openalex-snapshot
Mechanistic and therapeutic insights gained from studying rare skeletal diseases
inferred← citeshttps://doi.org/10.1016/j.bone.2016.08.026openalex-snapshot
C-type natriuretic peptide restores impaired skeletal growth in a murine model of glucocorticoid-induced growth retardation
inferred← citeshttps://doi.org/10.1016/j.bone.2017.05.016openalex-snapshot
Activated FGFR3 promotes bone formation via accelerating endochondral ossification in mouse model of distraction osteogenesis
inferred← citeshttps://doi.org/10.1016/j.bone.2018.06.001openalex-snapshot
Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes
inferred← citeshttps://doi.org/10.1016/j.bone.2020.115320openalex-snapshot
Male mice with elevated C-type natriuretic peptide-dependent guanylyl cyclase-B activity have increased osteoblasts, bone mass and bone strength
inferred← citeshttps://doi.org/10.1016/j.bone.2020.115579openalex-snapshot
Novel therapeutic approaches for the treatment of achondroplasia
inferred← citeshttps://doi.org/10.1016/j.bone.2025.117722openalex-snapshot
Real-world safety and age-dependent effectiveness of vosoritide in achondroplasia: A single-center retrospective analysis of transition from growth hormone to vosoritide
inferred← citeshttps://doi.org/10.1016/j.bonr.2026.101905openalex-snapshot
Phosphodiesterase inhibitors as emerging therapeutics for skeletal disorders: A comprehensive review of mechanisms and repurposing potential
inferred← citeshttps://doi.org/10.1016/j.cellsig.2011.09.001openalex-snapshot
Guanylyl cyclase structure, function and regulation
inferred← citeshttps://doi.org/10.1016/j.celrep.2021.109380openalex-snapshot
Mechanical load regulates bone growth via periosteal Osteocrin
inferred← citeshttps://doi.org/10.1016/j.ddmod.2004.11.014openalex-snapshot
Model systems for human muscoskeletal diseases
inferred← citeshttps://doi.org/10.1016/j.devcel.2007.09.016openalex-snapshot
Snail1 Is a Transcriptional Effector of FGFR3 Signaling during Chondrogenesis and Achondroplasias
inferred← citeshttps://doi.org/10.1016/j.ebiom.2019.01.010openalex-snapshot
Suppressing UPR-dependent overactivation of FGFR3 signaling ameliorates SLC26A2-deficient chondrodysplasias
inferred← citeshttps://doi.org/10.1016/j.eclinm.2023.102258openalex-snapshot
Once-weekly TransCon CNP (navepegritide) in children with achondroplasia (ACcomplisH): a phase 2, multicentre, randomised, double-blind, placebo-controlled, dose-escalation trial
inferred← citeshttps://doi.org/10.1016/j.ejphar.2008.02.002openalex-snapshot
Effect of PPADS on achondroplasic chondrocytes: Inhibition of FGF receptor type 3 over-activity
inferred← citeshttps://doi.org/10.1016/j.ejphar.2013.04.005openalex-snapshot
Oleanolic acid increases plasma ANP levels via an accentuation of cardiac ANP synthesis and secretion in rats
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.05.022openalex-snapshot
8-Nitro-cGMP promotes bone growth through expansion of growth plate cartilage
inferred← citeshttps://doi.org/10.1016/j.gendis.2024.101436openalex-snapshot
Advances in the mechanism and therapies of achondroplasia
inferred← citeshttps://doi.org/10.1016/j.gep.2018.04.002openalex-snapshot
The expression of fgfr3 in the zebrafish head
inferred← citeshttps://doi.org/10.1016/j.ghir.2006.03.016openalex-snapshot
C-type natriuretic peptide in growth: A new paradigm
inferred← citeshttps://doi.org/10.1016/j.gim.2022.08.015openalex-snapshot
Growth parameters in children with achondroplasia: A 7-year, prospective, multinational, observational study
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2012.08.001openalex-snapshot
A novel method for the large-scale production of PG-CNP37, a C-type natriuretic peptide analogue
inferred← citeshttps://doi.org/10.1016/j.jbspin.2007.06.007openalex-snapshot
Achondroplasia: From genotype to phenotype
inferred← citeshttps://doi.org/10.1016/j.jchb.2012.05.007openalex-snapshot
Selection of skull morphological traits for sexual dimorphism analysis
inferred← citeshttps://doi.org/10.1016/j.joca.2014.07.018openalex-snapshot
Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function
inferred← citeshttps://doi.org/10.1016/j.joca.2015.01.002openalex-snapshot
A new prescription for growth? Statins, cholesterol and cartilage homeostasis
inferred← citeshttps://doi.org/10.1016/j.joca.2021.11.017openalex-snapshot
Expanding horizons of achondroplasia treatment: current options and future developments
inferred← citeshttps://doi.org/10.1016/j.jor.2019.05.006openalex-snapshot
Analogs of C-type natriuretic peptide as a potential new non-surgical treatment strategy in knee osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.medj.2024.11.019openalex-snapshot
Sustained growth-promoting effects of vosoritide in children with achondroplasia from an ongoing phase 3 extension study
inferred← citeshttps://doi.org/10.1016/j.metabol.2009.09.026openalex-snapshot
Effect of nutrition on plasma C-type natriuretic peptide forms in adult sheep: evidence for enhanced C-type natriuretic peptide degradation during caloric restriction
inferred← citeshttps://doi.org/10.1016/j.mrrev.2013.11.001openalex-snapshot
The paradox of FGFR3 signaling in skeletal dysplasia: Why chondrocytes growth arrest while other cells over proliferate
inferred← citeshttps://doi.org/10.1016/j.niox.2018.03.007openalex-snapshot
Nitric oxide and cyclic GMP functions in bone
inferred← citeshttps://doi.org/10.1016/j.peptides.2004.08.027openalex-snapshot
C-type natriuretic peptide and guanylyl cyclase B receptor
inferred← citeshttps://doi.org/10.1016/j.peptides.2008.04.020openalex-snapshot
Reduced ability of C-type natriuretic peptide (CNP) to activate natriuretic peptide receptor B (NPR-B) causes dwarfism in lbab−/− mice
inferred← citeshttps://doi.org/10.1016/j.peptides.2009.07.023openalex-snapshot
Skeletal contributions to plasma CNP forms: Evidence from regional sampling in growing lambs
inferred← citeshttps://doi.org/10.1016/j.peptides.2011.11.005openalex-snapshot
Plasma C-type natriuretic peptide levels in healthy children
inferred← citeshttps://doi.org/10.1016/j.peptides.2017.09.008openalex-snapshot
Design and evaluation of novel natriuretic peptide derivatives with improved pharmacokinetic and pharmacodynamic properties
inferred← citeshttps://doi.org/10.1016/j.peptides.2018.08.006openalex-snapshot
Natriuretic peptides in human heart: Novel insight into their molecular forms, functions, and diagnostic use
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2010.12.005openalex-snapshot
Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2024.108708openalex-snapshot
C-type natriuretic peptide (CNP): The cardiovascular system and beyond
inferred← citeshttps://doi.org/10.1016/j.regpep.2007.09.022openalex-snapshot
ProCNP and CNP are expressed primarily in male genital organs
inferred← citeshttps://doi.org/10.1016/j.rhum.2007.06.011openalex-snapshot
L’achondroplasie : du génotype au phénotype
inferred← citeshttps://doi.org/10.1016/j.semcdb.2015.12.005openalex-snapshot
Altered FGF signalling in congenital craniofacial and skeletal disorders
inferred← citeshttps://doi.org/10.1016/j.tem.2009.04.003openalex-snapshot
FGFs in endochondral skeletal development
inferred← citeshttps://doi.org/10.1016/j.tice.2025.102940openalex-snapshot
TACC3 facilitates chondrocyte differentiation by attenuating abnormally activated FGFR3 signaling in achondroplasia − An in vitro study
inferred← citeshttps://doi.org/10.1016/j.tripleo.2005.08.031openalex-snapshot
Abnormal oral mucosal light reflectance in achondroplasia
inferred← citeshttps://doi.org/10.1016/j.ydbio.2008.02.007openalex-snapshot
Ca2+/Calmodulin-dependent kinase II signaling causes skeletal overgrowth and premature chondrocyte maturation
inferred← citeshttps://doi.org/10.1016/j.ydbio.2008.04.031openalex-snapshot
Nitric oxide, C-type natriuretic peptide and cGMP as regulators of endochondral ossification
inferred← citeshttps://doi.org/10.1016/j.ydbio.2008.05.555openalex-snapshot
Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia
inferred← citeshttps://doi.org/10.1016/j.yexcr.2004.11.012openalex-snapshot
Cell responses to FGFR3 signalling: growth, differentiation and apoptosis
inferred← citeshttps://doi.org/10.1016/j.ygcen.2021.113797openalex-snapshot
Evolution of the membrane/particulate guanylyl cyclase: From physicochemical sensors to hormone receptors
inferred← citeshttps://doi.org/10.1016/j.ymgme.2007.06.014openalex-snapshot
C-natriuretic peptide: An important regulator of cartilage
inferred← citeshttps://doi.org/10.1016/s0140-6736(20)31541-5openalex-snapshot
Once-daily, subcutaneous vosoritide therapy in children with achondroplasia: a randomised, double-blind, phase 3, placebo-controlled, multicentre trial
inferred← citeshttps://doi.org/10.1016/s0929-693x(09)74104-1openalex-snapshot
Approches translationnelles chez l’enfant
inferred← citeshttps://doi.org/10.1017/erm.2012.4openalex-snapshot
FGFR3 targeting strategies for achondroplasia
inferred← citeshttps://doi.org/10.1038/boneres.2014.3openalex-snapshot
Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models
inferred← citeshttps://doi.org/10.1038/d41586-023-02647-wopenalex-snapshot
Is a boost to height a boost to health? Dwarfism therapies spark controversy
inferred← citeshttps://doi.org/10.1038/nrc1697openalex-snapshot
Urothelial tumorigenesis: a tale of divergent pathways
inferred← citeshttps://doi.org/10.1038/nrendo.2015.165openalex-snapshot
Short and tall stature: a new paradigm emerges
inferred← citeshttps://doi.org/10.1038/s41436-021-01287-7openalex-snapshot
Safe and persistent growth-promoting effects of vosoritide in children with achondroplasia: 2-year results from an open-label, phase 3 extension study
inferred← citeshttps://doi.org/10.1038/s41467-026-69507-9openalex-snapshot
Excess FGFR3 signaling in achondroplasia disrupts turnover of resting zone chondrocytes via CREB signaling
inferred← citeshttps://doi.org/10.1038/s41598-018-28742-xopenalex-snapshot
Live imaging analysis of the growth plate in a murine long bone explanted culture system
inferred← citeshttps://doi.org/10.1038/s41598-019-44975-wopenalex-snapshot
Exogenous C-type natriuretic peptide therapy for impaired skeletal growth in a murine model of glucocorticoid treatment
inferred← citeshttps://doi.org/10.1038/s41598-021-03593-1openalex-snapshot
Evidence of feedback regulation of C-type natriuretic peptide during Vosoritide therapy in Achondroplasia
inferred← citeshttps://doi.org/10.1038/srep10554openalex-snapshot
The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth
inferred← citeshttps://doi.org/10.1042/bsr20130025openalex-snapshot
Mutations in Tyr808 reveal a potential auto-inhibitory mechanism of guanylate cyclase-B regulation
inferred← citeshttps://doi.org/10.1051/medsci/20082410794openalex-snapshot
L’ostéocrine, une nouvelle molécule de signalisation osseuse
inferred← citeshttps://doi.org/10.1056/nejmc1910394openalex-snapshot
C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia
inferred← citeshttps://doi.org/10.1056/nejmoa1813446openalex-snapshot
C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia
inferred← citeshttps://doi.org/10.1073/pnas.1514250112openalex-snapshot
Musclin is an activity-stimulated myokine that enhances physical endurance
inferred← citeshttps://doi.org/10.1073/pnas.2314802121openalex-snapshot
ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period
inferred← citeshttps://doi.org/10.1074/jbc.c500024200openalex-snapshot
A Loss-of-Function Mutation in Natriuretic Peptide Receptor 2 (Npr2) Gene Is Responsible for Disproportionate Dwarfism in cn/cn Mouse
inferred← citeshttps://doi.org/10.1074/jbc.m109.083626openalex-snapshot
NF449 Is a Novel Inhibitor of Fibroblast Growth Factor Receptor 3 (FGFR3) Signaling Active in Chondrocytes and Multiple Myeloma Cells
inferred← citeshttps://doi.org/10.1074/jbc.m117.780536openalex-snapshot
Skeletal overgrowth-causing mutations mimic an allosterically activated conformation of guanylyl cyclase-B that is inhibited by 2,4,6,-trinitrophenyl ATP
inferred← citeshttps://doi.org/10.1074/jbc.m410148200openalex-snapshot
Fibroblast Growth Factor (FGF) 18 Signals through FGF Receptor 3 to Promote Chondrogenesis
inferred← citeshttps://doi.org/10.1074/jbc.m503640200openalex-snapshot
Gene Disruption of Spred-2 Causes Dwarfism
inferred← citeshttps://doi.org/10.1074/jbc.m606144200openalex-snapshot
Bisindolylmaleimide I Suppresses Fibroblast Growth Factor-mediated Activation of Erk MAP Kinase in Chondrocytes by Preventing Shp2 Association with the Frs2 and Gab1 Adaptor Proteins
inferred← citeshttps://doi.org/10.1074/jbc.m708596200openalex-snapshot
Osteocrin Is a Specific Ligand of the Natriuretic Peptide Clearance Receptor That Modulates Bone Growth
inferred← citeshttps://doi.org/10.1080/14728214.2021.2005577openalex-snapshot
Emerging therapies for Achondroplasia: changing the rules of the game
inferred← citeshttps://doi.org/10.1080/17446651.2024.2390416openalex-snapshot
Progress in managing children with achondroplasia
inferred← citeshttps://doi.org/10.1083/jcb.200707176openalex-snapshot
The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord
inferred← citeshttps://doi.org/10.1086/422013openalex-snapshot
Mutations in the Transmembrane Natriuretic Peptide Receptor NPR-B Impair Skeletal Growth and Cause Acromesomelic Dysplasia, Type Maroteaux
inferred← citeshttps://doi.org/10.1089/tea.2007.0035openalex-snapshot
Differential Effects of Natriuretic Peptide Stimulation on Tissue-Engineered Cartilage
inferred← citeshttps://doi.org/10.1089/ten.2007.0035openalex-snapshot
Differential Effects of Natriuretic Peptide Stimulation on Tissue-Engineered Cartilage
inferred← citeshttps://doi.org/10.1093/ejendo/lvag082openalex-snapshot
Navepegritide combined with lonapegsomatropin for the treatment of children with achondroplasia: 52-week results from the phase 2 COACH trial
inferred← citeshttps://doi.org/10.1093/hmg/ddi161openalex-snapshot
Sustained ERK1/2 but not STAT1 or 3 activation is required for thanatophoric dysplasia phenotypes in PC12 cells
inferred← citeshttps://doi.org/10.1093/hmg/ddm266openalex-snapshot
BNP is a transcriptional target of the short stature homeobox gene SHOX
inferred← citeshttps://doi.org/10.1093/hmg/ddn339openalex-snapshot
FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway
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