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Mechanisms of envelope permeability and antibiotic influx and efflux in Gram-negative bacteria
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Polymyxin Combinations: Pharmacokinetics and Pharmacodynamics for Rationale Use
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A fluorescent carbapenem for structure function studies of penicillin-binding proteins, β-lactamases, and β-lactam sensors
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Mechanisms of RND multidrug efflux pumps
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Outer membrane permeability and antibiotic resistance
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Drug transport mechanism of the AcrB efflux pump
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Resistance to imipenem, cefepime, and cefpirome associated with mutation in Omp36 osmoporin of Enterobacter aerogenes
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Practical applications and feasibility of efflux pump inhibitors in the clinic—A vision for applied use
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Antimicrobial Resistance in the Intensive Care Unit: Mechanisms, Epidemiology, and Management of Specific Resistant Pathogens
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Molecular Mechanisms Underlying Bacterial Persisters
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Discovery and development of new antibacterial agents targeting Gram-negative bacteria in the era of pandrug resistance: is the future promising?
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Treatment of MDR-Gram negative infections in the 21st century: a never ending threat for clinicians
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Physical methods to quantify small antibiotic molecules uptake into Gram-negative bacteria
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Strategies for bypassing the membrane barrier in multidrug resistant Gram‐negative bacteria
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An adaptive response of Enterobacter aerogenes to imipenem: regulation of porin balance in clinical isolates
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Crystal Structure of Osmoporin OmpC from E. coli at 2.0 Å
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Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa
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Polymyxins and their novel derivatives
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Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells
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Structure, mechanism and cooperation of bacterial multidrug transporters
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The Binding of Antibiotics in OmpF Porin
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Thinking Outside the “Bug”: A Unique Assay To Measure Intracellular Drug Penetration in Gram-Negative Bacteria
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Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It
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General Platform for Systematic Quantitative Evaluation of Small-Molecule Permeability in Bacteria
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Crystal structures explain functional properties of two E. coli porins
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Crystal structure of bacterial multidrug efflux transporter AcrB
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Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
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Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
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Structural basis for the inhibition of bacterial multidrug exporters
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Structure of the AcrAB–TolC multidrug efflux pump
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A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans
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Tripartite assembly of RND multidrug efflux pumps
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In vitro transport activity of the fully assembled MexAB-OprM efflux pump from Pseudomonas aeruginosa
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Advances in understanding bacterial outer-membrane biogenesis
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The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria
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Microspectrometric insights on the uptake of antibiotics at the single bacterial cell level
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Siderophore-dependent iron uptake systems as gates for antibiotic Trojan horse strategies against Pseudomonas aeruginosa
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A new mechanism of antibiotic resistance in Enterobacteriaceae induced by a structural modification of the major porin
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Protected environments allow parallel evolution of a bacterial pathogen in a patient subjected to long‐term antibiotic therapy
inferredcites →https://doi.org/10.1073/pnas.0901695106openalex-snapshot
Kinetic behavior of the major multidrug efflux pump AcrB of Escherichia coli
inferredcites →https://doi.org/10.1073/pnas.1114944109openalex-snapshot
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
inferredcites →https://doi.org/10.1073/pnas.1310333110openalex-snapshot
Permeation rates of penicillins indicate that Escherichia coli porins function principally as nonspecific channels
inferredcites →https://doi.org/10.1073/pnas.1316084111openalex-snapshot
Contribution of phenotypic heterogeneity to adaptive antibiotic resistance
inferredcites →https://doi.org/10.1073/pnas.152206799openalex-snapshot
Designed to penetrate: Time-resolved interaction of single antibiotic molecules with bacterial pores
inferredcites →https://doi.org/10.1073/pnas.1525143113openalex-snapshot
Aminoacyl β-naphthylamides as substrates and modulators of AcrB multidrug efflux pump
inferredcites →https://doi.org/10.1073/pnas.1602472113openalex-snapshot
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives
inferredcites →https://doi.org/10.1074/jbc.m114.585869openalex-snapshot
High Salt Concentrations Increase Permeability through OmpC Channels of Escherichia coli
inferredcites →https://doi.org/10.1074/jbc.m115.690156openalex-snapshot
Molecular Basis of Filtering Carbapenems by Porins from β-Lactam-resistant Clinical Strains of Escherichia coli
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A Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane in Escherichia coli
inferredcites →https://doi.org/10.1093/cid/cit152openalex-snapshot
10 x '20 Progress--Development of New Drugs Active Against Gram-Negative Bacilli: An Update From the Infectious Diseases Society of America
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Porin expression in clinical isolates of Klebsiella pneumoniae
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Sensitivity of Escherichia coli to various β‐lactams is determined by the interplay of outer membrane permeability and degradation by periplasmic β‐lactamases: a quantitative predictive treatment
inferredcites →https://doi.org/10.1111/j.1574-6976.2011.00290.xopenalex-snapshot
Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria
inferredcites →https://doi.org/10.1126/science.1131542openalex-snapshot
Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism
inferredcites →https://doi.org/10.1128/aac.01585-15openalex-snapshot
Role of the Outer Membrane and Porins in Susceptibility of β-Lactamase-Producing Enterobacteriaceae to Ceftazidime-Avibactam
inferredcites →https://doi.org/10.1128/aac.12.3.368openalex-snapshot
Function of the Outer Membrane of Escherichia coli as a Permeability Barrier to Beta-Lactam Antibiotics
inferredcites →https://doi.org/10.1128/aac.27.1.84openalex-snapshot
Diffusion of beta-lactam antibiotics through the porin channels of Escherichia coli K-12
inferredcites →https://doi.org/10.1128/aac.33.1.27openalex-snapshot
Fluorometric assay for fleroxacin uptake by bacterial cells
inferredcites →https://doi.org/10.1128/aac.40.12.2854openalex-snapshot
Prevalence of outer membrane porin alteration in beta-lactam-antibiotic-resistant Enterobacter aerogenes
inferredcites →https://doi.org/10.1128/aac.44.2.311-315.2000openalex-snapshot
Substitutions in the Eyelet Region Disrupt Cefepime Diffusion through the Escherichia coli OmpF Channel
inferredcites →https://doi.org/10.1128/cmr.00030-10openalex-snapshot
Challenges of Antibacterial Discovery
inferredcites →https://doi.org/10.1128/cmr.00117-14openalex-snapshot
The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria
inferredcites →https://doi.org/10.1128/jb.153.1.232-240.1983openalex-snapshot
Porin channels in Escherichia coli: studies with beta-lactams in intact cells
inferredcites →https://doi.org/10.1128/jb.153.1.241-252.1983openalex-snapshot
Porin channels in Escherichia coli: studies with liposomes reconstituted from purified proteins
inferredcites →https://doi.org/10.1128/jb.162.2.722-727.1985openalex-snapshot
Ion selectivity of gram-negative bacterial porins
inferredcites →https://doi.org/10.1128/mmbr.67.4.593-656.2003openalex-snapshot
Molecular Basis of Bacterial Outer Membrane Permeability Revisited
inferredcites →https://doi.org/10.1371/journal.pbio.0050007openalex-snapshot
Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors
inferredcites →https://doi.org/10.1371/journal.pbio.1000317openalex-snapshot
Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli
inferredcites →https://doi.org/10.1371/journal.pgen.0040002openalex-snapshot
Dissecting the Genetic Components of Adaptation of Escherichia coli to the Mouse Gut
inferredcites →https://doi.org/10.1371/journal.pone.0005453openalex-snapshot
How β-Lactam Antibiotics Enter Bacteria: A Dialogue with the Porins
inferredcites →https://doi.org/10.1371/journal.pone.0025825openalex-snapshot
Altered Antibiotic Transport in OmpC Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. coli
inferredcites →https://doi.org/10.1371/journal.pone.0038624openalex-snapshot
Antibiotic Transport in Resistant Bacteria: Synchrotron UV Fluorescence Microscopy to Determine Antibiotic Accumulation with Single Cell Resolution
inferredcites →https://doi.org/10.1371/journal.pone.0097903openalex-snapshot
Crystal Structure of the Neisseria gonorrhoeae MtrD Inner Membrane Multidrug Efflux Pump
inferredcites →https://doi.org/10.1371/journal.pone.0124814openalex-snapshot
A Mass Spectrometry-Based Assay for Improved Quantitative Measurements of Efflux Pump Inhibition
inferredcites →https://doi.org/10.1371/journal.pone.0138828openalex-snapshot
In Vivo Evolution of Bacterial Resistance in Two Cases of Enterobacter aerogenes Infections during Treatment with Imipenem
inferredcites →https://doi.org/10.1371/journal.pone.0152917openalex-snapshot
A Transporter Interactome Is Essential for the Acquisition of Antimicrobial Resistance to Antibiotics
inferredcites →https://doi.org/10.14348/molcells.2015.2277openalex-snapshot
Structure of the Tripartite Multidrug Efflux Pump AcrAB-TolC Suggests an Alternative Assembly Mode
inferredcites →https://doi.org/10.1529/biophysj.105.075192openalex-snapshot
Interaction of Zwitterionic Penicillins with the OmpF Channel Facilitates Their Translocation
inferredcites →https://doi.org/10.2174/092986711796150469openalex-snapshot
An Original Deal for New Molecule: Reversal of Efflux Pump Activity, A Rational Strategy to Combat Gram-Negative Resistant Bacteria
inferredcites →https://doi.org/10.3389/fmicb.2014.00290openalex-snapshot
Siderophores as “Trojan Horses”: tackling multidrug resistance?
inferredcites →https://doi.org/10.3389/fmicb.2015.00327openalex-snapshot
Structural basis of RND-type multidrug exporters
inferredcites →https://doi.org/10.3389/fmicb.2015.00421openalex-snapshot
Recent advances toward a molecular mechanism of efflux pump inhibition
inferredcites →https://doi.org/10.3389/fmicb.2015.00660openalex-snapshot
Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa
inferredcites →https://doi.org/10.7554/elife.03145openalex-snapshot
Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Bioactive profile of edible nasturtium and rose flowers during simulated gastrointestinal digestion
inferred← citeshttps://doi.org/10.1016/j.foodhyd.2021.106709openalex-snapshot
Biobased films of nanocellulose and mango leaf extract for active food packaging: Supercritical impregnation versus solvent casting
inferred← citeshttps://doi.org/10.1016/j.heliyon.2022.e10010openalex-snapshot
Biosynthesis and antibacterial activity of silver nanoparticles using Flos Sophorae Immaturus extract
inferred← citeshttps://doi.org/10.1016/j.insi.2026.100632openalex-snapshot
Strategies and role of artificial intelligence to combat antimicrobial resistance: A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.jcis.2020.06.125openalex-snapshot
One-pot synthesis of natural amine-modified biocompatible carbon quantum dots with antibacterial activity
inferred← citeshttps://doi.org/10.1016/j.jddst.2021.102730openalex-snapshot
Polyelectrolytic nature of chitosan: Influence on physicochemical properties and synthesis of nanoparticles
inferred← citeshttps://doi.org/10.1016/j.jece.2025.118940openalex-snapshot
Exploration of the antiviral and antibacterial efficacy of hydrozincite/graphene oxide nanocomposites: Molecular docking and in vitro investigations
inferred← citeshttps://doi.org/10.1016/j.jes.2024.05.023openalex-snapshot
Assessing the effectiveness and mechanisms of Fe/PS, Fe/H2O2, and O3 treatment for water disinfection: Spotlight on VBNC bacteria
inferred← citeshttps://doi.org/10.1016/j.jff.2018.11.028openalex-snapshot
Applications of new functions for inducing host defense peptides and synergy sterilization of medium chain fatty acids in substituting in-feed antibiotics
inferred← citeshttps://doi.org/10.1016/j.jgar.2018.10.009openalex-snapshot
Modulation of antimicrobial resistance in clinical isolates of Enterobacter aerogenes: A strategy combining antibiotics and chemosensitisers
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.134057openalex-snapshot
The intracellular concentrations of fluoroquinolones determined the antibiotic resistance response of Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.138236openalex-snapshot
Environmental high-risk efflux pumps mediate concurrent enhancement of resistance and virulence in reclaimed water from urban wastewater treatment plants
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.139010openalex-snapshot
Interfacial processes governing tetracycline-induced resistance on clay minerals
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.140201openalex-snapshot
Effects of sub-inhibitory antibiotic exposure on elemental cycling genes in an aquatic microbial community
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2025.112836openalex-snapshot
The antibacterial activity and selectivity of bismuth(III) tris(8-hydroxyquinolinates)
inferred← citeshttps://doi.org/10.1016/j.jpha.2019.11.002openalex-snapshot
Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification
inferred← citeshttps://doi.org/10.1016/j.jphotochem.2023.114619openalex-snapshot
N-aryl-2-(trifluoromethyl)benzo[b][1,8]naphthyridin-4(1H)-one as convenient platform to design high photostable and long-lived dyad fluorophore with potential application in live-cell imaging
inferred← citeshttps://doi.org/10.1016/j.jprot.2018.05.006openalex-snapshot
Identification and efficacy of glycine, serine and threonine metabolism in potentiating kanamycin-mediated killing of Edwardsiella piscicida
inferred← citeshttps://doi.org/10.1016/j.jtumed.2021.03.004openalex-snapshot
Extensive drug-resistance in strains of Escherichia coli and Klebsiella pneumoniae isolated from paediatric urinary tract infections
inferred← citeshttps://doi.org/10.1016/j.mattod.2026.103426openalex-snapshot
Stimuli-responsive two-dimensional material-based composites for anti-bacterial and anti-inflammatory synergies
inferred← citeshttps://doi.org/10.1016/j.micpath.2018.03.024openalex-snapshot
Antibacterial naphthoquinone derivatives targeting resistant strain Gram-negative bacteria in biofilms
inferred← citeshttps://doi.org/10.1016/j.micpath.2024.107099openalex-snapshot
Comparative genomic analysis reveals distinct virulence and resistance mechanisms in 21 bacterial fish pathogens
inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.135905openalex-snapshot
Antibacterial and catalytic applications of two water-soluble pillar[5]arene derivatives
inferred← citeshttps://doi.org/10.1016/j.molstruc.2026.146910openalex-snapshot
Multitarget isoxazole–1,2,3-triazole hybrids: From synthesis to antimicrobial, antioxidant and Culex pipiens larvicidal applications supported by molecular simulations
inferred← citeshttps://doi.org/10.1016/j.mtbio.2020.100084openalex-snapshot
A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria
inferred← citeshttps://doi.org/10.1016/j.nxmate.2025.101540openalex-snapshot
Fighting back against bacterial resistance: Harnessing nanocarrier strategies to counter antibiotic efflux pumps
inferred← citeshttps://doi.org/10.1016/j.progpolymsci.2025.102040openalex-snapshot
Recent advances in the molecular engineering of synthetic polypeptides: Design, synthesis, functionality, and biological applications
inferred← citeshttps://doi.org/10.1016/j.resmic.2017.11.004openalex-snapshot
Reconstitution of the activity of RND efflux pumps: a “bottom-up” approach
inferred← citeshttps://doi.org/10.1016/j.resmic.2017.11.005openalex-snapshot
Fluorescence enlightens RND pump activity and the intrabacterial concentration of antibiotics
inferred← citeshttps://doi.org/10.1016/j.resmic.2018.02.006openalex-snapshot
The Escherichia coli effluxome
inferred← citeshttps://doi.org/10.1016/j.resmic.2020.09.005openalex-snapshot
Comparative proteomics reveals essential mechanisms for osmotolerance in Gluconacetobacter diazotrophicus
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2021.152885openalex-snapshot
Copper-based fungicide copper hydroxide accelerates the evolution of antibiotic resistance via gene mutations in Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.snb.2019.03.091openalex-snapshot
Fluorescent fingerprint bacteria by multi-channel magnetic fluorescent nanosensor
inferred← citeshttps://doi.org/10.1016/j.surfin.2025.107567openalex-snapshot
Unveiling the phyto-corona of green-synthesized zinc oxide nanoparticles responsible for enhanced antibacterial property
inferred← citeshttps://doi.org/10.1016/j.tice.2025.103259openalex-snapshot
Biomimetic silk fibroin/alginate scaffolds incorporating ZnO nanoparticles and Citrus aurantium extract for epidermal differentiation of human adipose-derived stem cells
inferred← citeshttps://doi.org/10.1016/j.watres.2025.123206openalex-snapshot
Synergistic effects of quaternary ammonium compounds and antibiotics on the evolution of antibiotic resistance
inferred← citeshttps://doi.org/10.1016/j.watres.2025.123326openalex-snapshot
Stratified biofilm structure of MABR enabling efficient ammonia removal from aquaculture medicated bath wastewater
inferred← citeshttps://doi.org/10.1016/s1773-035x(20)30060-5openalex-snapshot
Le rôle des porines dans la résistance aux antibiotiques
inferred← citeshttps://doi.org/10.1021/acs.analchem.1c00521openalex-snapshot
Microorganisms as Bio-SPE Materials for Extraction of Pharmaceutical Drugs: Mechanism of Extraction
inferred← citeshttps://doi.org/10.1021/acs.analchem.9b00574openalex-snapshot
Unveiling the Modulating Role of Extracellular pH in Permeation and Accumulation of Small Molecules in Subcellular Compartments of Gram-negative Escherichia coli using Nonlinear Spectroscopy
inferred← citeshttps://doi.org/10.1021/acs.bioconjchem.1c00116openalex-snapshot
Nanotargeting of Resistant Infections with a Special Emphasis on the Biofilm Landscape
inferred← citeshttps://doi.org/10.1021/acs.bioconjchem.3c00488openalex-snapshot
Photoswitchable Antibiotic Hybrids: Spacer Length-Dependent Photochemical Control of Antibacterial Activity
inferred← citeshttps://doi.org/10.1021/acs.chemrev.0c01213openalex-snapshot
How to Enter a Bacterium: Bacterial Porins and the Permeation of Antibiotics
inferred← citeshttps://doi.org/10.1021/acs.chemrev.1c00138openalex-snapshot
Metallo-β-lactamases in the Age of Multidrug Resistance: From Structure and Mechanism to Evolution, Dissemination, and Inhibitor Design
inferred← citeshttps://doi.org/10.1021/acs.chemrev.8b00369openalex-snapshot
Enzymatic Transition States and Drug Design
inferred← citeshttps://doi.org/10.1021/acs.est.4c11346openalex-snapshot
Basic Nitrogenous Heterocyclic Rings at the 7-Position of Fluoroquinolones Foster Their Induction of Antibiotic Resistance in Escherichia coli
inferred← citeshttps://doi.org/10.1021/acs.est.5c06042openalex-snapshot
Antibiotics or Heavy Metals in Livestock Wastewater: Which One Is the Main Driver for the Development and Spread of Antibiotic Resistance under Coexposure?
inferred← citeshttps://doi.org/10.1021/acs.jafc.5c06813openalex-snapshot
Decoding Multidrug Resistance Mechanism in Fusarium graminearum : Reduced Intracellular Drug Accumulation
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c01282openalex-snapshot
Tackling Antimicrobial Resistance with Small Molecules Targeting LsrK: Challenges and Opportunities
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c02185openalex-snapshot
Chemical Highlights Supporting the Role of Lipid A in Efficient Biological Adaptation of Gram-Negative Bacteria to External Stresses
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.1c01482openalex-snapshot
Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c01831openalex-snapshot
Guiding the Way: Traditional Medicinal Chemistry Inspiration for Rational Gram-Negative Drug Design
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c02052openalex-snapshot
Design, Synthesis, and Biological Evaluation of Indole Derivatives Targeting LsrK as AI-2 Quorum Sensing Inhibitors
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.8b00114openalex-snapshot
Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-Pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-negative Bacteria
inferred← citeshttps://doi.org/10.1021/acs.jpcb.1c00607openalex-snapshot
Microscopic Approach to Intrinsic Antibiotic Resistance
inferred← citeshttps://doi.org/10.1021/acs.jpclett.4c01189openalex-snapshot
Role of AcrAB-TolC and Its Components in Influx–Efflux Dynamics of QAC Drugs in Escherichia coli Revealed Using SHG Spectroscopy
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.2c00258openalex-snapshot
Nanoparticle Fraught Liposomes: A Platform for Increased Antibiotic Selectivity in Multidrug Resistant Bacteria
inferred← citeshttps://doi.org/10.1021/acs.nanolett.3c04545openalex-snapshot
Nano-Emulsified Perfluorooctyl Bromide Can Infiltrate Gram-Negative Bacteria and Sensitize Them to Ultrasound
inferred← citeshttps://doi.org/10.1021/acsami.1c15868openalex-snapshot
Tug-of-War between Covalent Binding and Electrostatic Interaction Effectively Killing E. coli without Detectable Resistance
inferred← citeshttps://doi.org/10.1021/acsanm.4c06859openalex-snapshot
Dual Enzyme-Mimic Popcorn-Shaped Copper–Erbium Nanoalloys for Combating Gram-Negative Pathogens and Promoting Wound Healing
inferred← citeshttps://doi.org/10.1021/acsbiomaterials.4c02045openalex-snapshot
Biomedical Engineering on Smart Polymeric Nanoparticle–Hydrogel Platforms for Efficient Antibiotic Delivery against Bacterial-Infected Wounds
inferred← citeshttps://doi.org/10.1021/acsbiomedchemau.5c00273openalex-snapshot
Advancements in Technologies Targeting Horizontal Gene Transfer─Routes to Control Drug Resistance Evolution
inferred← citeshttps://doi.org/10.1021/acschembio.1c00626openalex-snapshot
Short Peptides and Their Mimetics as Potent Antibacterial Agents and Antibiotic Adjuvants
inferred← citeshttps://doi.org/10.1021/acschembio.3c00073openalex-snapshot
Detection of Cysteine Sulfenic Acid on E. coli Proteins with a Biotin-Benzoboroxole Probe
inferred← citeshttps://doi.org/10.1021/acschembio.9b00529openalex-snapshot
Leveraging Peptide Substrate Libraries to Design Inhibitors of Bacterial Lon Protease
inferred← citeshttps://doi.org/10.1021/acsinfecdis.0c00015openalex-snapshot
Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries
inferred← citeshttps://doi.org/10.1021/acsinfecdis.0c00389openalex-snapshot
An Assay for Periplasm Entry Advances the Development of Chimeric Peptide Antibiotics
inferred← citeshttps://doi.org/10.1021/acsinfecdis.1c00171openalex-snapshot
Azaindole Based Potentiator of Antibiotics against Gram-Negative Bacteria
inferred← citeshttps://doi.org/10.1021/acsinfecdis.2c00223openalex-snapshot
Tea Tree Oil Nanoemulsion Potentiates Antibiotics against Multidrug-Resistant Escherichia coli
inferred← citeshttps://doi.org/10.1021/acsinfecdis.2c00263openalex-snapshot
Analysis of Orthogonal Efflux and Permeation Properties of Compounds Leads to the Discovery of New Efflux Pump Inhibitors
inferred← citeshttps://doi.org/10.1021/acsinfecdis.2c00406openalex-snapshot
Development of Antimicrobial Peptide–Antibiotic Conjugates to Improve the Outer Membrane Permeability of Antibiotics Against Gram-Negative Bacteria
inferred← citeshttps://doi.org/10.1021/acsinfecdis.2c00435openalex-snapshot
Measurement of Small Molecule Accumulation into Diderm Bacteria
inferred← citeshttps://doi.org/10.1021/acsinfecdis.2c00567openalex-snapshot
Molecular Signatures of the Eagle Effect Induced by the Artificial Siderophore Conjugate LP-600 in E. coli
inferred← citeshttps://doi.org/10.1021/acsinfecdis.3c00408openalex-snapshot
Outer Membrane Proteins and Efflux Pumps Mediated Multi-Drug Resistance in Salmonella: Rising Threat to Antimicrobial Therapy
inferred← citeshttps://doi.org/10.1021/acsinfecdis.4c00252openalex-snapshot
Growth Phase Contribution in Dictating Drug Transport and Subcellular Accumulation inside Escherichia coli
inferred← citeshttps://doi.org/10.1021/acsinfecdis.4c00404openalex-snapshot
Niacin-Cholic Acid-Peptide Conjugate Act as a Potential Antibiotic Adjuvant to Mitigate Polymicrobial Infections Caused by Gram-Negative Pathogens
inferred← citeshttps://doi.org/10.1021/acsinfecdis.5c00635openalex-snapshot
Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria
inferred← citeshttps://doi.org/10.1021/acsinfecdis.6c00322openalex-snapshot
Tobramycin-Peptide Nucleic Acids Synergize with Polymyxin B and Other Bioactive Compounds to Inhibit Growth of Gram-Negative Bacteria
inferred← citeshttps://doi.org/10.1021/acsinfecdis.7b00165openalex-snapshot
In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics
inferred← citeshttps://doi.org/10.1021/acsinfecdis.8b00093openalex-snapshot
Molecular Probes for the Determination of Subcellular Compound Exposure Profiles in Gram-Negative Bacteria
inferred← citeshttps://doi.org/10.1021/acsinfecdis.8b00108openalex-snapshot
Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins
inferred← citeshttps://doi.org/10.1021/acsinfecdis.9b00256openalex-snapshot
Size Matters and How You Measure It: A Gram-Negative Antibacterial Example Exceeding Typical Molecular Weight Limits
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.6c00164openalex-snapshot
Nicotinamide-Based Covalent Inhibitors of tRNA (m1G37) Methyltransferase (TrmD) to Increase Antibacterial Activity
inferred← citeshttps://doi.org/10.1021/acsnano.3c11179openalex-snapshot
Coassembled Multicomponent Protein Nanoparticles Elicit Enhanced Antibacterial Activity
inferred← citeshttps://doi.org/10.1021/acsnano.4c06501openalex-snapshot
Siderophore-Functionalized Nanodrug for Treating Antibiotic-Resistant Bacteria
inferred← citeshttps://doi.org/10.1021/acsnano.4c12664openalex-snapshot
Intracellular Quantification of an Antibiotic Metal Complex in Single Cells of Escherichia coli Using Cryo-X-ray Fluorescence Nanoimaging
inferred← citeshttps://doi.org/10.1021/acsnano.8b07251openalex-snapshot
Pathogen-Specific Polymeric Antimicrobials with Significant Membrane Disruption and Enhanced Photodynamic Damage To Inhibit Highly Opportunistic Bacteria
inferred← citeshttps://doi.org/10.1021/acsnano.9b05766openalex-snapshot
Bacteria-Responsive Biomimetic Selenium Nanosystem for Multidrug-Resistant Bacterial Infection Detection and Inhibition
inferred← citeshttps://doi.org/10.1021/jacs.0c04427openalex-snapshot
Gram-Negative Antibiotic Active Through Inhibition of an Essential Riboswitch
inferred← citeshttps://doi.org/10.1021/jacs.5c10219openalex-snapshot
A Bioinspired Lipopeptide Surmounts Therapeutic Dilemmas of Gram-Positive and Gram-Negative Polymicrobial Infection
inferred← citeshttps://doi.org/10.1021/jacsau.2c00532openalex-snapshot
Chemical Basis of Combination Therapy to Combat Antibiotic Resistance
inferred← citeshttps://doi.org/10.1021/jacsau.3c00025openalex-snapshot
Expanding Knowledge of Methylotrophic Capacity: Structure and Properties of the Rough-Type Lipopolysaccharide from Methylobacterium extorquens and Its Role on Membrane Resistance to Methanol
inferred← citeshttps://doi.org/10.1038/nprot.2018.036openalex-snapshot
Spectrofluorimetric quantification of antibiotic drug concentration in bacterial cells for the characterization of translocation across bacterial membranes
inferred← citeshttps://doi.org/10.1038/s41467-023-37827-9openalex-snapshot
In vivo bioluminescence imaging of natural bacteria within deep tissues via ATP-binding cassette sugar transporter
inferred← citeshttps://doi.org/10.1038/s41467-023-39264-0openalex-snapshot
A data-driven approach for predicting the impact of drugs on the human microbiome
inferred← citeshttps://doi.org/10.1038/s41467-023-40494-5openalex-snapshot
Profiling cell envelope-antibiotic interactions reveals vulnerabilities to β-lactams in a multidrug-resistant bacterium
inferred← citeshttps://doi.org/10.1038/s41467-026-70138-3openalex-snapshot
Bioengineered ROS-tolerant probiotic reshapes gut microbiota-host axis to ameliorate type 2 diabetes in male mice
inferred← citeshttps://doi.org/10.1038/s41557-024-01516-xopenalex-snapshot
Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria
inferred← citeshttps://doi.org/10.1038/s41557-026-02124-7openalex-snapshot
A synthetic cell microreactor with two types of interacting dynamic DNA-based pores
inferred← citeshttps://doi.org/10.1038/s41579-019-0294-2openalex-snapshot
Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria
inferred← citeshttps://doi.org/10.1038/s41589-020-00674-6openalex-snapshot
Defining new chemical space for drug penetration into Gram-negative bacteria
inferred← citeshttps://doi.org/10.1038/s41598-017-00945-8openalex-snapshot
Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria
inferred← citeshttps://doi.org/10.1038/s41598-017-06503-6openalex-snapshot
In-vivo loss of carbapenem resistance by extensively drug-resistant Klebsiella pneumoniae during treatment via porin expression modification
inferred← citeshttps://doi.org/10.1038/s41598-017-08775-4openalex-snapshot
Fluoroquinolone structure and translocation flux across bacterial membrane
inferred← citeshttps://doi.org/10.1038/s41598-017-17772-6openalex-snapshot
Increasing the permeability of Escherichia coli using MAC13243
inferred← citeshttps://doi.org/10.1038/s41598-021-83339-1openalex-snapshot
Tolerance engineering in Deinococcus geothermalis by heterologous efflux pumps
inferred← citeshttps://doi.org/10.1038/s41598-021-91905-wopenalex-snapshot
Exploring antimicrobial resistance to beta-lactams, aminoglycosides and fluoroquinolones in E. coli and K. pneumoniae using proteogenomics
inferred← citeshttps://doi.org/10.1038/s41598-025-10208-6openalex-snapshot
Measurement and prediction of small molecule retention by Gram-negative bacteria based on a large-scale LC/MS screen
inferred← citeshttps://doi.org/10.1038/s42003-020-0929-xopenalex-snapshot
The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux
inferred← citeshttps://doi.org/10.1038/s42003-022-04024-1openalex-snapshot
A framework for dissecting affinities of multidrug efflux transporter AcrB to fluoroquinolones
inferred← citeshttps://doi.org/10.1038/s42003-022-04035-yopenalex-snapshot
Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane
inferred← citeshttps://doi.org/10.1038/s42003-024-07168-4openalex-snapshot
Advances in methods and concepts provide new insight into antibiotic fluxes across the bacterial membrane
inferred← citeshttps://doi.org/10.1038/s42004-024-01161-yopenalex-snapshot
Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors
inferred← citeshttps://doi.org/10.1038/s44259-024-00023-wopenalex-snapshot
Multidrug efflux in Gram-negative bacteria: structural modifications in active compounds leading to efflux pump avoidance
inferred← citeshttps://doi.org/10.1038/s44259-025-00089-0openalex-snapshot
Innovative perspectives on the discovery of small molecule antibiotics
inferred← citeshttps://doi.org/10.1039/9781837072026-00069openalex-snapshot
Phages for Fighting Against Antimicrobial Resistance
inferred← citeshttps://doi.org/10.1039/c9md00124gopenalex-snapshot
Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux
inferred← citeshttps://doi.org/10.1039/d0nr01366hopenalex-snapshot
Development of polycationic micelles as an efficient delivery system of antibiotics for overcoming the biological barriers to reverse multidrug resistance in Escherichia coli
inferred← citeshttps://doi.org/10.1039/d2ra02272aopenalex-snapshot
Development of a bioorthogonal fluorescence-based assay for assessing drug uptake and delivery in bacteria
inferred← citeshttps://doi.org/10.1039/d5ra09180bopenalex-snapshot
Determination of the structure and dynamics of linear polypeptide gramicidin A at atomic-scale resolution
inferred← citeshttps://doi.org/10.1051/jbio/2017020openalex-snapshot
Transports des antibiotiques et perméabilité membranaire : nouvelles perspectives afin de combattre la résistance bactérienne
inferred← citeshttps://doi.org/10.1080/10408398.2025.2589460openalex-snapshot
Targeting bacterial cell envelope stress responses to advance the next generation of antimicrobial approaches
inferred← citeshttps://doi.org/10.1080/17435889.2025.2574839openalex-snapshot
LPS-focused nanomedicine for potent antibacterial therapy
inferred← citeshttps://doi.org/10.1080/17460441.2018.1455660openalex-snapshot
Overcoming problems of poor drug penetration into bacteria: challenges and strategies for medicinal chemists
inferred← citeshttps://doi.org/10.1080/17460441.2020.1767065openalex-snapshot
Antibacterial medicinal chemistry – what can we design for?
inferred← citeshttps://doi.org/10.1080/21505594.2022.2135273openalex-snapshot
Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis
inferred← citeshttps://doi.org/10.1080/21505594.2024.2399983openalex-snapshot
N-acetylcysteine promotes doxycycline resistance in the bacterial pathogen Edwardsiella tarda
inferred← citeshttps://doi.org/10.1093/femsmc/xtag003openalex-snapshot
Enhanced antibacterial activity of antimicrobial peptide—antibiotic combinations against multidrug-resistant bacteria
inferred← citeshttps://doi.org/10.1093/jac/dkad122openalex-snapshot
Contribution of efflux and mutations in fluoroquinolone susceptibility in MDR enterobacterial isolates: a quantitative and molecular study
inferred← citeshttps://doi.org/10.1093/jac/dkx432openalex-snapshot
Effect of Staphylococcus aureus Tet38 native efflux pump on in vivo response to tetracycline in a murine subcutaneous abscess model
inferred← citeshttps://doi.org/10.1093/jac/dky396openalex-snapshot
Antibiotics and efflux: combined spectrofluorimetry and mass spectrometry to evaluate the involvement of concentration and efflux activity in antibiotic intracellular accumulation
inferred← citeshttps://doi.org/10.1099/jmm.0.001129openalex-snapshot
A simple phenotypic test for detecting the contribution of outer membrane permeability to carbapenem resistance
inferred← citeshttps://doi.org/10.1099/mgen.0.001156openalex-snapshot
Exploring the genetic basis of natural resistance to microcins
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