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Tripartite assembly of RND multidrug efflux pumps
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/s00232-014-9707-3openalex-snapshot
Amphipol-Mediated Screening of Molecular Orthoses Specific for Membrane Protein Targets
inferredcites →https://doi.org/10.1016/j.bbamem.2010.06.019openalex-snapshot
Structure of reconstituted bacterial membrane efflux pump by cryo-electron tomography
inferredcites →https://doi.org/10.1016/j.bbapap.2008.12.015openalex-snapshot
Drug transport mechanism of the AcrB efflux pump
inferredcites →https://doi.org/10.1016/j.chembiol.2011.02.011openalex-snapshot
Sequential Mechanism of Assembly of Multidrug Efflux Pump AcrAB-TolC
inferredcites →https://doi.org/10.1016/j.febslet.2004.10.097openalex-snapshot
A model of a transmembrane drug‐efflux pump from Gram‐negative bacteria
inferredcites →https://doi.org/10.1016/j.febslet.2006.09.005openalex-snapshot
Directed evolution of a bacterial efflux pump: Adaptation of the E. coli TolC exit duct to the Pseudomonas MexAB translocase
inferredcites →https://doi.org/10.1016/j.jmb.2009.02.048openalex-snapshot
Crystal Structure of the Periplasmic Component of a Tripartite Macrolide-Specific Efflux Pump
inferredcites →https://doi.org/10.1016/j.jmb.2009.04.001openalex-snapshot
Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1016/j.jsb.2005.01.001openalex-snapshot
Trimeric structure of OprN and OprM efflux proteins from , by 2D electron crystallography
inferredcites →https://doi.org/10.1016/j.pep.2004.10.002openalex-snapshot
Multidrug transporter MexB of Pseudomonas aeruginosa: overexpression, purification, and initial structural characterization
inferredcites →https://doi.org/10.1016/j.str.2005.11.015openalex-snapshot
Conformational Flexibility in the Multidrug Efflux System Protein AcrA
inferredcites →https://doi.org/10.1016/j.str.2010.01.018openalex-snapshot
Structural and Dynamical Insights into the Opening Mechanism of P. aeruginosa OprM Channel
inferredcites →https://doi.org/10.1016/s0076-6879(09)64011-8openalex-snapshot
Reconstitution of Membrane Proteins in Phospholipid Bilayer Nanodiscs
inferredcites →https://doi.org/10.1021/bi050452uopenalex-snapshot
Direct Interaction of Multidrug Efflux Transporter AcrB and Outer Membrane Channel TolC Detected via Site-Directed Disulfide Cross-Linking
inferredcites →https://doi.org/10.1021/ja0393574openalex-snapshot
Directed Self-Assembly of Monodisperse Phospholipid Bilayer Nanodiscs with Controlled Size
inferredcites →https://doi.org/10.1038/35016007openalex-snapshot
Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
inferredcites →https://doi.org/10.1038/nature01050openalex-snapshot
Crystal structure of bacterial multidrug efflux transporter AcrB
inferredcites →https://doi.org/10.1038/nature05076openalex-snapshot
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
inferredcites →https://doi.org/10.1038/nature09743openalex-snapshot
Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli
inferredcites →https://doi.org/10.1038/nature12300openalex-snapshot
Structural basis for the inhibition of bacterial multidrug exporters
inferredcites →https://doi.org/10.1038/nature13205openalex-snapshot
Structure of the AcrAB–TolC multidrug efflux pump
inferredcites →https://doi.org/10.1038/nrd2200openalex-snapshot
Waltzing transporters and 'the dance macabre' between humans and bacteria
inferredcites →https://doi.org/10.1073/pnas.0400375101openalex-snapshot
Structure of the periplasmic component of a bacterial drug efflux pump
inferredcites →https://doi.org/10.1073/pnas.0900693106openalex-snapshot
The assembled structure of a complete tripartite bacterial multidrug efflux pump
inferredcites →https://doi.org/10.1073/pnas.0902400106openalex-snapshot
A coordinated network of transporters with overlapping specificities provides a robust survival strategy
inferredcites →https://doi.org/10.1073/pnas.0906601106openalex-snapshot
Kinetic control of TolC recruitment by multidrug efflux complexes
inferredcites →https://doi.org/10.1073/pnas.1114944109openalex-snapshot
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
inferredcites →https://doi.org/10.1073/pnas.1210093109openalex-snapshot
Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance
inferredcites →https://doi.org/10.1074/jbc.c400164200openalex-snapshot
Crystal Structure of the Membrane Fusion Protein, MexA, of the Multidrug Transporter in Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1074/jbc.c400445200openalex-snapshot
Crystal Structure of the Drug Discharge Outer Membrane Protein, OprM, of Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1074/jbc.m111.246595openalex-snapshot
Evidence for the Assembly of a Bacterial Tripartite Multidrug Pump with a Stoichiometry of 3:6:3
inferredcites →https://doi.org/10.1107/s0907444902013963openalex-snapshot
Purification, crystallization and preliminary diffraction studies of AcrB, an inner-membrane multi-drug efflux protein
inferredcites →https://doi.org/10.1111/j.1348-0421.2005.tb03696.xopenalex-snapshot
Gene Cloning and Properties of the RND‐Type Multidrug Efflux Pumps MexPQ‐OpmE and MexMN‐OprM from Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1111/j.1365-2958.2004.04158.xopenalex-snapshot
Interactions underlying assembly of the Escherichia coli AcrAB–TolC multidrug efflux system
inferredcites →https://doi.org/10.1111/j.1365-2958.2010.07068.xopenalex-snapshot
AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening
inferredcites →https://doi.org/10.1111/j.1574-6976.2011.00290.xopenalex-snapshot
Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria
inferredcites →https://doi.org/10.1111/mmi.12211openalex-snapshot
Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump
inferredcites →https://doi.org/10.1126/science.1131542openalex-snapshot
Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism
inferredcites →https://doi.org/10.1128/aac.01866-13openalex-snapshot
Characterization of a Novel Pyranopyridine Inhibitor of the AcrAB Efflux Pump of Escherichia coli
inferredcites →https://doi.org/10.1128/aac.03283-14openalex-snapshot
Molecular Mechanism of MBX2319 Inhibition of Escherichia coli AcrB Multidrug Efflux Pump and Comparison with Other Inhibitors
inferredcites →https://doi.org/10.1128/aac.45.1.105-116.2001openalex-snapshot
Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa : Novel Agents for Combination Therapy
inferredcites →https://doi.org/10.1128/cmr.00117-14openalex-snapshot
The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria
inferredcites →https://doi.org/10.1128/jb.01276-07openalex-snapshot
Fitting Periplasmic Membrane Fusion Proteins to Inner Membrane Transporters: Mutations That Enable Escherichia coli AcrA To Function with Pseudomonas aeruginosa MexB
inferredcites →https://doi.org/10.1128/jb.184.23.6499-6507.2002openalex-snapshot
Chimeric Analysis of the Multicomponent Multidrug Efflux Transporters from Gram-Negative Bacteria
inferredcites →https://doi.org/10.1128/jb.186.24.8533-8536.2004openalex-snapshot
Interaction between the TolC and AcrA Proteins of a Multidrug Efflux System of Escherichia coli
inferredcites →https://doi.org/10.1146/annurev.biochem.78.082907.145923openalex-snapshot
Multidrug Resistance in Bacteria
inferredcites →https://doi.org/10.1371/journal.pbio.0050007openalex-snapshot
Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors
inferredcites →https://doi.org/10.1371/journal.pcbi.1000806openalex-snapshot
Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations
inferredcites →https://doi.org/10.14348/molcells.2015.2277openalex-snapshot
Structure of the Tripartite Multidrug Efflux Pump AcrAB-TolC Suggests an Alternative Assembly Mode
inferredcites →https://doi.org/10.1529/biophysj.105.080010openalex-snapshot
Flexibility in a Drug Transport Accessory Protein: Molecular Dynamics Simulations of MexA
inferredcites →https://doi.org/10.2174/15680266113136660220openalex-snapshot
RND Efflux Pumps: Structural Information Translated into Function and Inhibition Mechanisms
inferredcites →https://doi.org/10.3389/fmicb.2012.00408openalex-snapshot
MexXY multidrug efflux system of Pseudomonas aeruginosa
inferredcites →https://doi.org/10.5936/csbj.201302008openalex-snapshot
MOLECULAR DYNAMICS COMPUTER SIMULATIONS OF MULTIDRUG RND EFFLUX PUMPS
inferredcites →https://doi.org/10.7554/elife.03145openalex-snapshot
Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/1873-3468.13929openalex-snapshot
Tripartite transporters as mechanotransmitters in periplasmic alternating‐access mechanisms
inferred← citeshttps://doi.org/10.1002/9783527808465.emc2016.6802openalex-snapshot
Tripartite assembly of RND multidrug efflux pumps in nanodisc and amphipol
inferred← citeshttps://doi.org/10.1002/ange.201713395openalex-snapshot
Glycosyl‐Substituted Dicarboxylates as Detergents for the Extraction, Overstabilization, and Crystallization of Membrane Proteins
inferred← citeshttps://doi.org/10.1002/anie.201713395openalex-snapshot
Glycosyl‐Substituted Dicarboxylates as Detergents for the Extraction, Overstabilization, and Crystallization of Membrane Proteins
inferred← citeshttps://doi.org/10.1002/cbdv.202301820openalex-snapshot
Synergistic Antibacterial Activity of Gallic Acid Based Chalcone Indl 2 by Inhibiting Efflux Pump Transporters
inferred← citeshttps://doi.org/10.1002/med.21591openalex-snapshot
Efflux pump inhibitors of clinically relevant multidrug resistant bacteria
inferred← citeshttps://doi.org/10.1002/prot.26539openalex-snapshot
Amphiphilic peptide Mastoparan‐B induces conformational changes within the AdeB efflux pump, down‐regulates ade B gene expression, and restores antibiotic susceptibility in an MDR strain of Acinetobacter baumannii
inferred← citeshttps://doi.org/10.1007/978-1-0716-5316-6_10openalex-snapshot
Computer Simulations of Multidrug Efflux Pumps of the Resistance–Nodulation–Cell Division Superfamily
inferred← citeshttps://doi.org/10.1007/978-1-0716-5316-6_5openalex-snapshot
Labeling of Specific Residues of the Multidrug Transporter AcrB with Its Fluorescent Substrate
inferred← citeshttps://doi.org/10.1007/978-1-4939-9512-7_25openalex-snapshot
Nanodiscs as a New Tool to Examine Lipid–Protein Interactions
inferred← citeshttps://doi.org/10.1007/978-3-031-08491-1_5openalex-snapshot
Antibiotic Resistance in Pseudomonas
inferred← citeshttps://doi.org/10.1007/978-3-031-58843-3_1openalex-snapshot
Structures and Efflux Mechanisms of the AcrAB-TolC Pump
inferred← citeshttps://doi.org/10.1007/978-3-319-39658-3_1openalex-snapshot
Structures and Transport Mechanisms of RND Efflux Pumps
inferred← citeshttps://doi.org/10.1007/978-3-319-39658-3_14openalex-snapshot
Antimicrobial Drug Efflux Pumps in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1007/978-3-319-39658-3_5openalex-snapshot
Multidrug Efflux in the Context of Two-Membrane Cell Envelopes
inferred← citeshttps://doi.org/10.1007/978-3-319-73148-3_3openalex-snapshot
Alternatives to Detergents for Handling Membrane Proteins in Aqueous Solutions
inferred← citeshttps://doi.org/10.1007/978-3-319-78538-7_4openalex-snapshot
Resistance of Gram-negative Bacilli to Antimicrobials
inferred← citeshttps://doi.org/10.1007/978-981-13-9871-1_12openalex-snapshot
Efflux Pump Inhibitors and Their Role in the Reversal of Drug Resistance
inferred← citeshttps://doi.org/10.1007/978-981-15-7098-8_8openalex-snapshot
Antimicrobial Magnetic Nanoparticles: A Potential Antibiotic Agent in the Era of Multi-Drug Resistance
inferred← citeshttps://doi.org/10.1007/s00203-017-1434-6openalex-snapshot
Evolution of structural fitness and multifunctional aspects of mycobacterial RND family transporters
inferred← citeshttps://doi.org/10.1007/s00232-020-00161-yopenalex-snapshot
High-Yield Preparation of Outer Membrane Protein Efflux Pumps by in Vitro Refolding is Concentration Dependent
inferred← citeshttps://doi.org/10.1007/s10482-026-02394-8openalex-snapshot
Efflux-mediated carbapenem resistance: unveiling genetic drivers, clinical implications, and strategies for global antimicrobial stewardship
inferred← citeshttps://doi.org/10.1007/s10532-018-9857-6openalex-snapshot
An RND transporter in the monoterpene metabolism of Castellaniella defragrans
inferred← citeshttps://doi.org/10.1007/s10822-025-00741-xopenalex-snapshot
Unveiling structural dynamics and allosteric vulnerabilities in Klebsiella pneumoniae KPHS_11890: an integrated DRKG-MD study
inferred← citeshttps://doi.org/10.1007/s10886-017-0889-xopenalex-snapshot
Microbial Resistance Mechanisms to the Antibiotic and Phytotoxin Fusaric Acid
inferred← citeshttps://doi.org/10.1007/s10930-026-10321-zopenalex-snapshot
Structure-Based Drug Design Targeting the Substrate-Binding Pocket of MexB
inferred← citeshttps://doi.org/10.1007/s11274-026-05063-0openalex-snapshot
Operonic architecture of bacterial metal response: envelope constraints, evolutionary mobility, and bioremediation design rules
inferred← citeshttps://doi.org/10.1007/s11427-025-3175-9openalex-snapshot
Broad synergistic effects of an AMP with multiple antibiotics against drug-resistant bacteria via multifaceted mechanisms
inferred← citeshttps://doi.org/10.1007/s12275-019-8520-1openalex-snapshot
Recent paradigm shift in the assembly of bacterial tripartite efflux pumps and the type I secretion system
inferred← citeshttps://doi.org/10.1007/s41745-017-0032-6openalex-snapshot
Structural Biology Meets Drug Resistance: An Overview on Multidrug Resistance Transporters
inferred← citeshttps://doi.org/10.1007/s43440-020-00160-9openalex-snapshot
Efflux pump inhibitors: new updates
inferred← citeshttps://doi.org/10.1016/bs.mie.2025.08.024openalex-snapshot
Reconstitution of RND tripartite multidrug complexes for single-particle electron microscopy
inferred← citeshttps://doi.org/10.1016/bs.mie.2025.08.026openalex-snapshot
Using hydrogen/deuterium exchange mass spectrometry to understand bacterial membrane efflux proteins
inferred← citeshttps://doi.org/10.1016/bs.mie.2025.08.028openalex-snapshot
MexB/inhibitor complexes preparation for crystallography and cryo-EM, comparison and possible pitfalls
inferred← citeshttps://doi.org/10.1016/bs.mie.2025.09.019openalex-snapshot
Reconstitution of tripartite efflux pumps MexAB-OprM and MacAB-TolC in biomimetic systems
inferred← citeshttps://doi.org/10.1016/bs.mie.2025.10.001openalex-snapshot
Computational approaches for modelling multidrug efflux pumps of the resistance nodulation-cell division superfamily
inferred← citeshttps://doi.org/10.1016/j.anaerobe.2023.102696openalex-snapshot
Identification of a Czc-like operon of the periodontal pathobiont Porphyromonas gingivalis involved in metal ion efflux
inferred← citeshttps://doi.org/10.1016/j.bbagen.2017.07.014openalex-snapshot
Biophysical characterization of E. coli TolC interaction with the known blocker hexaamminecobalt
inferred← citeshttps://doi.org/10.1016/j.bbamem.2017.08.024openalex-snapshot
Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance
inferred← citeshttps://doi.org/10.1016/j.bbamem.2017.10.005openalex-snapshot
Using a SMALP platform to determine a sub-nm single particle cryo-EM membrane protein structure
inferred← citeshttps://doi.org/10.1016/j.bbamem.2019.01.013openalex-snapshot
Minimal nanodisc without exogenous lipids for stabilizing membrane proteins in detergent-free buffer
inferred← citeshttps://doi.org/10.1016/j.bbamem.2020.183478openalex-snapshot
Bicelles and nanodiscs for biophysical chemistry
inferred← citeshttps://doi.org/10.1016/j.bbamem.2020.183488openalex-snapshot
Structural characterization of the EmrAB-TolC efflux complex from E. coli
inferred← citeshttps://doi.org/10.1016/j.bbamem.2022.184075openalex-snapshot
Cell-Free Synthesis and Reconstitution of Bax in Nanodiscs: Comparison between Wild-Type Bax and a Constitutively Active Mutant
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.09.059openalex-snapshot
Hexameric assembly of membrane fusion protein YknX of the sporulation delaying efflux pump from Bacillus amyloliquefaciens
inferred← citeshttps://doi.org/10.1016/j.bbrc.2021.03.046openalex-snapshot
Structural characterization of a 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa PAO1
inferred← citeshttps://doi.org/10.1016/j.biochi.2023.01.004openalex-snapshot
TolC-AcrA complex formation monitored by time dependent single-channel electrophysiology
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2018.11.013openalex-snapshot
Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies
inferred← citeshttps://doi.org/10.1016/j.bmcl.2017.01.042openalex-snapshot
Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance
inferred← citeshttps://doi.org/10.1016/j.bpc.2021.106732openalex-snapshot
How to best estimate the viscosity of lipid bilayers
inferred← citeshttps://doi.org/10.1016/j.bpj.2021.08.016openalex-snapshot
Lpp positions peptidoglycan at the AcrA-TolC interface in the AcrAB-TolC multidrug efflux pump
inferred← citeshttps://doi.org/10.1016/j.bpj.2023.02.007openalex-snapshot
Detergent headgroups control TolC folding in vitro
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2025.144234openalex-snapshot
Importance of the envelope in Escherichia coli resistance to lithium
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2026.115904openalex-snapshot
An artificial model of ATP-binding cassette mediated transport
inferred← citeshttps://doi.org/10.1016/j.csbj.2021.11.042openalex-snapshot
Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA
inferred← citeshttps://doi.org/10.1016/j.drudis.2018.07.003openalex-snapshot
Updates on the pathogenicity status of Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1016/j.drudis.2020.07.011openalex-snapshot
Computational approaches in efflux pump inhibitors: current status and prospects
inferred← citeshttps://doi.org/10.1016/j.drup.2016.06.007openalex-snapshot
Multidrug efflux pumps as main players in intrinsic and acquired resistance to antimicrobials
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.11.102openalex-snapshot
Design, synthesis and biological activity evaluation of novel 4-subtituted 2-naphthamide derivatives as AcrB inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.111910openalex-snapshot
Structural optimization of natural product nordihydroguaretic acid to discover novel analogues as AcrB inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejmech.2023.115148openalex-snapshot
Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance
inferred← citeshttps://doi.org/10.1016/j.envres.2021.111321openalex-snapshot
Embelin-loaded chitosan gold nanoparticles interact synergistically with ciprofloxacin by inhibiting efflux pumps in multidrug-resistant Pseudomonas aeruginosa and Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.envres.2022.115063openalex-snapshot
Integrated analysis of transcriptomic and protein-protein interaction data reveals cadmium stress response in Geobacter sulfurreducens
inferred← citeshttps://doi.org/10.1016/j.fm.2020.103416openalex-snapshot
Phenotype and genomic background of Arcobacter butzleri strains and taxogenomic assessment of the species
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Genomic insights revealed the environmental adaptability of Planococcus halotolerans Y50 isolated from petroleum-contaminated soil on the Qinghai-Tibet Plateau
inferred← citeshttps://doi.org/10.1016/j.genrep.2017.09.004openalex-snapshot
Contribution of efflux systems to the detergent resistance, cytotoxicity, and biofilm formation of Vibrio vulnificus
inferred← citeshttps://doi.org/10.1016/j.heliyon.2025.e43721openalex-snapshot
1,4-Naphthoquinone analogues promote cross-protection to antibiotics through glutathione-dependent MexT-mediated MexEF-OprN expression in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1016/j.ibiod.2025.106096openalex-snapshot
Efflux pumps of Pseudomonas aeruginosa and their regulatory mechanisms underlying multidrug resistance
inferred← citeshttps://doi.org/10.1016/j.ijmm.2019.04.005openalex-snapshot
Roles of DevBCA-like ABC transporters in the physiology of Anabaena sp. PCC 7120
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Distribution of and associations between ARGs and pathogenic bacteria in soils affected by heavy metal contamination in mining areas
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.138236openalex-snapshot
Environmental high-risk efflux pumps mediate concurrent enhancement of resistance and virulence in reclaimed water from urban wastewater treatment plants
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.139975openalex-snapshot
Synergistic effects of micro/nanoplastics and Cu(II) on horizontal transfer of antibiotic resistance genes: New insight targeting on cell surface properties
inferred← citeshttps://doi.org/10.1016/j.jmb.2017.09.018openalex-snapshot
Switch Loop Flexibility Affects Substrate Transport of the AcrB Efflux Pump
inferred← citeshttps://doi.org/10.1016/j.jmb.2021.167005openalex-snapshot
Structural Insights into Transporter-Mediated Drug Resistance in Infectious Diseases
inferred← citeshttps://doi.org/10.1016/j.jmb.2024.168652openalex-snapshot
Discovery and Characterization of Two Folded Intermediates for Outer Membrane Protein TolC Biogenesis
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.120391openalex-snapshot
Microbial resistance: The role of efflux pump superfamilies and their respective substrates
inferred← citeshttps://doi.org/10.1016/j.meegid.2021.104928openalex-snapshot
Comparative genome analysis of Corynebacterium species: The underestimated pathogens with high virulence potential
inferred← citeshttps://doi.org/10.1016/j.mib.2021.03.009openalex-snapshot
Bacterial efflux transporters’ polyspecificity – a gift and a curse?
inferred← citeshttps://doi.org/10.1016/j.resmic.2017.11.004openalex-snapshot
Reconstitution of the activity of RND efflux pumps: a “bottom-up” approach
inferred← citeshttps://doi.org/10.1016/j.resmic.2017.11.005openalex-snapshot
Fluorescence enlightens RND pump activity and the intrabacterial concentration of antibiotics
inferred← citeshttps://doi.org/10.1016/j.resmic.2018.01.002openalex-snapshot
Sequence- and structure-based computational analyses of Gram-negative tripartite efflux pumps in the context of bacterial membranes
inferred← citeshttps://doi.org/10.1016/j.resmic.2018.02.002openalex-snapshot
Trans-envelope multidrug efflux pumps of Gram-negative bacteria and their synergism with the outer membrane barrier
inferred← citeshttps://doi.org/10.1016/j.resmic.2018.05.003openalex-snapshot
Structure and mechanism of bacterial tripartite efflux pumps
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2022.160461openalex-snapshot
Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health
inferred← citeshttps://doi.org/10.1016/j.slasd.2025.100232openalex-snapshot
Antimicrobial resistance: Linking molecular mechanisms to public health impact
inferred← citeshttps://doi.org/10.1016/j.str.2020.09.001openalex-snapshot
A “Drug Sweeping” State of the TriABC Triclosan Efflux Pump from Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1016/j.tube.2017.08.001openalex-snapshot
MmpS5/MmpL5 as an efflux pump in Mycobacterium species
inferred← citeshttps://doi.org/10.1016/j.watres.2025.124310openalex-snapshot
Public goods-mediated bacterial interplay in aquatic ecosystems
inferred← citeshttps://doi.org/10.1016/j.ygeno.2019.11.008openalex-snapshot
Comparative genomics of Sphingopyxis spp. unravelled functional attributes
inferred← citeshttps://doi.org/10.1021/acs.chemrev.1c00055openalex-snapshot
Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria
inferred← citeshttps://doi.org/10.1021/acs.chemrev.6b00690openalex-snapshot
Nanodiscs in Membrane Biochemistry and Biophysics
inferred← citeshttps://doi.org/10.1021/acs.jcim.8b00957openalex-snapshot
Structural Features and Energetics of the Periplasmic Entrance Opening of the Outer Membrane Channel TolC Revealed by Molecular Dynamics Simulation and Markov State Model Analysis
inferred← citeshttps://doi.org/10.1021/acsinfecdis.3c00350openalex-snapshot
Combined Structure- and Ligand-Based Approach for the Identification of Inhibitors of AcrAB-TolC in Escherichia coli
inferred← citeshttps://doi.org/10.1021/acsinfecdis.5c00612openalex-snapshot
Modeling and Functional Characterization of Reconstituted Efflux Pump Components from Heterologous Gram-Negative Bacteria
inferred← citeshttps://doi.org/10.1021/acsinfecdis.8b00027openalex-snapshot
Antibacterial Drug Discovery: Some Assembly Required
inferred← citeshttps://doi.org/10.1021/acsinfecdis.8b00273openalex-snapshot
Titrating Levels of TolC in E. coli: A Sensitive Approach to Quantifying Efflux
inferred← citeshttps://doi.org/10.1021/acsinfecdis.9b00123openalex-snapshot
AcrAB–TolC Inhibition by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in Vitro and in Vivo
inferred← citeshttps://doi.org/10.1021/acsomega.0c02921openalex-snapshot
Probing the Dynamics of AcrB Through Disulfide Bond Formation
inferred← citeshttps://doi.org/10.1038/nmicrobiol.2017.1openalex-snapshot
Mechanisms of envelope permeability and antibiotic influx and efflux in Gram-negative bacteria
inferred← citeshttps://doi.org/10.1038/nmicrobiol.2017.70openalex-snapshot
Structure of the MacAB–TolC ABC-type tripartite multidrug efflux pump
inferred← citeshttps://doi.org/10.1038/s41420-024-02108-xopenalex-snapshot
The membrane insertion of the pro-apoptotic protein Bax is a Tom22-dependent multi-step process: a study in nanodiscs
inferred← citeshttps://doi.org/10.1038/s41467-017-02493-1openalex-snapshot
Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition
inferred← citeshttps://doi.org/10.1038/s41467-019-09463-9openalex-snapshot
Structures of the wild-type MexAB–OprM tripartite pump reveal its complex formation and drug efflux mechanism
inferred← citeshttps://doi.org/10.1038/s41467-019-10512-6openalex-snapshot
In situ structure and assembly of the multidrug efflux pump AcrAB-TolC
inferred← citeshttps://doi.org/10.1038/s41467-020-18770-5openalex-snapshot
Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex
inferred← citeshttps://doi.org/10.1038/s41467-021-27726-2openalex-snapshot
Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps
inferred← citeshttps://doi.org/10.1038/s41467-025-65038-xopenalex-snapshot
Assembly and inhibition of transferable TMexCD1-TOprJ1 efflux pump
inferred← citeshttps://doi.org/10.1038/s41467-026-70500-5openalex-snapshot
A model for drug transport across two membranes of Gram-negative bacteria by an MFS tripartite assembly
inferred← citeshttps://doi.org/10.1038/s41598-017-16497-wopenalex-snapshot
Dynamics of Intact MexAB-OprM Efflux Pump: Focusing on the MexA-OprM Interface
inferred← citeshttps://doi.org/10.1038/s41598-020-77339-wopenalex-snapshot
Effect of membrane fusion protein AdeT1 on the antimicrobial resistance of Escherichia coli
inferred← citeshttps://doi.org/10.1038/s41598-022-08903-9openalex-snapshot
A role for the periplasmic adaptor protein AcrA in vetting substrate access to the RND efflux transporter AcrB
inferred← citeshttps://doi.org/10.1038/s41598-024-52536-zopenalex-snapshot
Escherichia coli resistance mechanism AcrAB-TolC efflux pump interactions with commonly used antibiotics: a molecular dynamics study
inferred← citeshttps://doi.org/10.1038/s41598-025-18206-4openalex-snapshot
A novel role for colistin as an efflux pump inhibitor in multidrug-resistant Klebsiella pneumoniae
inferred← citeshttps://doi.org/10.1038/s42003-021-01997-3openalex-snapshot
Quantitative real-time analysis of the efflux by the MacAB-TolC tripartite efflux pump clarifies the role of ATP hydrolysis within mechanotransmission mechanism
inferred← citeshttps://doi.org/10.1038/srep41751openalex-snapshot
Quantification of Detergents Complexed with Membrane Proteins
inferred← citeshttps://doi.org/10.1042/bsr20180474openalex-snapshot
Reversing resistance to counter antimicrobial resistance in the World Health Organisation’s critical priority of most dangerous pathogens
inferred← citeshttps://doi.org/10.1042/ebc20160064openalex-snapshot
The role played by drug efflux pumps in bacterial multidrug resistance
inferred← citeshttps://doi.org/10.1051/jbio/2017020openalex-snapshot
Transports des antibiotiques et perméabilité membranaire : nouvelles perspectives afin de combattre la résistance bactérienne
inferred← citeshttps://doi.org/10.1080/13543776.2024.2348602openalex-snapshot
Recent trends and challenges to overcome Pseudomonas aeruginosa infections
inferred← citeshttps://doi.org/10.1080/17460441.2018.1514386openalex-snapshot
The development of efflux pump inhibitors to treat Gram-negative infections
inferred← citeshttps://doi.org/10.1093/jac/dkag272openalex-snapshot
Genome-wide network of antibiotic susceptibility in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1099/mic.0.000971openalex-snapshot
MexXY RND pump of Pseudomonas aeruginosa PA7 effluxes bi-anionic β-lactams carbenicillin and sulbenicillin when it partners with the outer membrane factor OprA but not with OprM
inferred← citeshttps://doi.org/10.1099/mic.0.001438openalex-snapshot
Molecular insights into the determinants of substrate specificity and efflux inhibition of the RND efflux pumps AcrB and AdeB
inferred← citeshttps://doi.org/10.1101/2020.06.16.154831openalex-snapshot
Quantum dot probes for the quantitative study of drug transport by the MacAB TolC efflux pump in lipid scaffolds
inferred← citeshttps://doi.org/10.1101/2021.10.05.463233openalex-snapshot
The membrane-proximal domain of the periplasmic adapter protein plays a role in vetting substrates utilising channels 1 and 2 of RND efflux transporters
inferred← citeshttps://doi.org/10.1101/2025.02.18.638599openalex-snapshot
Disassembly of the Escherichia coli AcrABZ-TolC efflux pump by ligand-mediated disruption of TolC-AcrA interfacial contacts
inferred← citeshttps://doi.org/10.1109/mnano.2025.3638506openalex-snapshot
Rapid Bacterial Antibiotic Resistance Identification With Microscale Electrochemical Impedance Spectroscopy Tomography
inferred← citeshttps://doi.org/10.1111/nyas.14239openalex-snapshot
AcrB: a mean, keen, drug efflux machine
inferred← citeshttps://doi.org/10.1111/nyas.14596openalex-snapshot
How to kill Pseudomonas —emerging therapies for a challenging pathogen
inferred← citeshttps://doi.org/10.1128/aac.01459-18openalex-snapshot
Two Regulators, PA3898 and PA2100, Modulate the Pseudomonas aeruginosa Multidrug Resistance MexAB-OprM and EmrAB Efflux Pumps and Biofilm Formation
inferred← citeshttps://doi.org/10.1128/aem.01447-24openalex-snapshot
Quantifying bacterial efflux within subcellular domains of Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1128/jb.00693-17openalex-snapshot
Characterization of a Unique Outer Membrane Protein Required for Oxidative Stress Resistance and Virulence of Francisella tularensis
inferred← citeshttps://doi.org/10.1128/mbio.00850-19openalex-snapshot
Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria
inferred← citeshttps://doi.org/10.1128/mspheredirect.00375-17openalex-snapshot
The Biofilm Inhibitor Carolacton Enters Gram-Negative Cells: Studies Using a TolC-Deficient Strain of Escherichia coli
inferred← citeshttps://doi.org/10.1128/spectrum.01936-24openalex-snapshot
Identification of novel amrR deletions as meropenem resistance mechanisms in clinical Burkholderia pseudomallei isolates
inferred← citeshttps://doi.org/10.1155/2022/5099312openalex-snapshot
Advances in Key Drug Target Identification and New Drug Development for Tuberculosis
inferred← citeshttps://doi.org/10.1177/25152564241231364openalex-snapshot
C ool-contacts : Cryo-Electron Microscopy of Membrane Contact Sites and Their Components
inferred← citeshttps://doi.org/10.1186/s12864-017-4109-4openalex-snapshot
Bacteriophages are the major drivers of Shigella flexneri serotype 1c genome plasticity: a complete genome analysis
inferred← citeshttps://doi.org/10.1186/s12866-018-1325-2openalex-snapshot
Multi-drug resistant Enterobacter bugandensis species isolated from the International Space Station and comparative genomic analyses with human pathogenic strains
inferred← citeshttps://doi.org/10.1186/s12866-024-03283-8openalex-snapshot
Characterization of genes related to the efflux pump and porin in multidrug-resistant Escherichia coli strains isolated from patients with COVID-19 after secondary infection
inferred← citeshttps://doi.org/10.1186/s12866-026-04847-6openalex-snapshot
Genetic variants of AcrAB and OqxAB and the impact of efflux pump inhibition on ciprofloxacin and amikacin resistance in clinical isolates of Klebsiella pneumoniae from Lima, Peru
inferred← citeshttps://doi.org/10.1186/s40168-022-01332-wopenalex-snapshot
Machine learning algorithm to characterize antimicrobial resistance associated with the International Space Station surface microbiome
inferred← citeshttps://doi.org/10.1242/jcs.263624openalex-snapshot
Surface protein machineries in Gram-negative bacteria
inferred← citeshttps://doi.org/10.1248/bpb.b23-00190openalex-snapshot
Point Mutation Analysis of the Drug Efflux Pump MexB in Clinical Isolates of Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.13005/bbra/3414openalex-snapshot
Efflux Pump Inhibitors and their Role in Combating Bacterial Drug Resistance
inferred← citeshttps://doi.org/10.13023/etd.2016.283openalex-snapshot
ASSEMBLY AND DEGRADATION OF A TRIMERIC MEMBRANE PROTEIN ACRB
inferred← citeshttps://doi.org/10.13023/etd.2017.419openalex-snapshot
Illuminate the Pathway of Membrane Protein Association and Degradation
inferred← citeshttps://doi.org/10.13023/etd.2021.275openalex-snapshot
Investigation of Multidrug Efflux Transporter AcrB in Escherichia coli
inferred← citeshttps://doi.org/10.1371/journal.pone.0184671openalex-snapshot
Bifurcation kinetics of drug uptake by Gram-negative bacteria
inferred← citeshttps://doi.org/10.1371/journal.ppat.1008101openalex-snapshot
Identification of binding residues between periplasmic adapter protein (PAP) and RND efflux pumps explains PAP-pump promiscuity and roles in antimicrobial resistance
inferred← citeshttps://doi.org/10.14232/phd.10335openalex-snapshot
Resistance reversing activity of plant-derived and novel synthetic compounds in bacterial models
inferred← citeshttps://doi.org/10.14232/phd.11330openalex-snapshot
Phage infection reinstates antibiotic sensitivity in MDR Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.17760/d20237471openalex-snapshot
Drug- and nanoparticle-encapsulating polymersome nanocarriers for the treatment of antibiotic-resistant infections
inferred← citeshttps://doi.org/10.17957/ijab/15.1801openalex-snapshot
Mechanisms of Antimicrobial Resistance in Pseudomonas aeruginosa and a Multi-Pronged Approach to Combat its Infection in Veterinary Science and Public Health: A Review
inferred← citeshttps://doi.org/10.21161/mjm.230260openalex-snapshot
Plasmid profiles and antibiotic resistance of Pseudomonas aeruginosa isolated from different clinical samples in Jordan
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1862196/v1openalex-snapshot
Evaluation of A22 Analogs as Gram-negative Antimicrobial Agents
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3183014/v1openalex-snapshot
Clove oil down regulates the expression of genes encoding the efflux pump, virulence factors and quorum sensing in MDR Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4468934/v1openalex-snapshot
One-step drug transport across two membranes of Gram-negative bacteria
inferred← citeshttps://doi.org/10.21248/gups.61913openalex-snapshot
Reconstitution and functional characterization of efflux pumps from Escherichia coli
inferred← citeshttps://doi.org/10.2147/ijn.s121956openalex-snapshot
The antimicrobial activity of nanoparticles: present situation and prospects for the future
inferred← citeshttps://doi.org/10.2174/0122113525298269240429130911openalex-snapshot
Phytochemicals as Adjuvant Therapies in RND Efflux-mediated Multidrug Resistant Pseudomonas aeruginosa Infections and Evaluation Techniques of Efflux Inhibitory Activities in Bacteria
inferred← citeshttps://doi.org/10.2174/0929867328666210614121222openalex-snapshot
Targeting Bacterial Membrane Proteins to Explore the Beneficial Effects of Natural Products: New Antibiotics against Drug Resistance
inferred← citeshttps://doi.org/10.2210/pdb6iok/pdbopenalex-snapshot
Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state)
inferred← citeshttps://doi.org/10.3389/978-2-88945-181-4openalex-snapshot
Antimicrobial Resistance and Virulence Common Mechanisms
inferred← citeshttps://doi.org/10.3389/fcimb.2018.00390openalex-snapshot
Quantitative Proteomics Reveals Antibiotics Resistance Function of Outer Membrane Proteins in Aeromonas hydrophila
inferred← citeshttps://doi.org/10.3389/fcimb.2021.665759openalex-snapshot
The Building Blocks of Antimicrobial Resistance in Pseudomonas aeruginosa: Implications for Current Resistance-Breaking Therapies
inferred← citeshttps://doi.org/10.3389/fcimb.2023.1203487openalex-snapshot
Vibrio cholerae RND efflux systems: mediators of stress responses, colonization and pathogenesis
inferred← citeshttps://doi.org/10.3389/fmicb.2016.01483openalex-snapshot
Multidrug Efflux Pumps at the Crossroad between Antibiotic Resistance and Bacterial Virulence
inferred← citeshttps://doi.org/10.3389/fmicb.2018.00204openalex-snapshot
Multiparametric Profiling for Identification of Chemosensitizers against Gram-Negative Bacteria
inferred← citeshttps://doi.org/10.3389/fmicb.2018.00950openalex-snapshot
Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective
inferred← citeshttps://doi.org/10.3389/fmicb.2021.783722openalex-snapshot
Survival Comes at a Cost: A Coevolution of Phage and Its Host Leads to Phage Resistance and Antibiotic Sensitivity of Pseudomonas aeruginosa Multidrug Resistant Strains
inferred← citeshttps://doi.org/10.3389/fmicb.2022.797444openalex-snapshot
Comparative Metagenomic Study of Rhizospheric and Bulk Mercury-Contaminated Soils in the Mining District of Almadén
inferred← citeshttps://doi.org/10.3389/fmicb.2023.1149418openalex-snapshot
The culmination of multidrug-resistant efflux pumps vs. meager antibiotic arsenal era: Urgent need for an improved new generation of EPIs
inferred← citeshttps://doi.org/10.3389/fmicb.2026.1794341openalex-snapshot
Antibiotic resistance in Aeromonas hydrophila associated with exposure to subtherapeutic levels of oxytetracycline
inferred← citeshttps://doi.org/10.3389/fmicb.2026.1915579openalex-snapshot
RND efflux pump inhibitor-like natural products as antibiotic adjuvants against multidrug-resistant gram-negative bacteria: a graded-evidence review
inferred← citeshttps://doi.org/10.3389/fmolb.2018.00057openalex-snapshot
Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures
inferred← citeshttps://doi.org/10.3389/fmolb.2020.00166openalex-snapshot
Mutations in the TolC Periplasmic Domain Affect Substrate Specificity of the AcrAB-TolC Pump
inferred← citeshttps://doi.org/10.3390/antibiotics10070774openalex-snapshot
Ever-Adapting RND Efflux Pumps in Gram-Negative Multidrug-Resistant Pathogens: A Race against Time
inferred← citeshttps://doi.org/10.3390/antibiotics10070830openalex-snapshot
Insight into the AcrAB-TolC Complex Assembly Process Learned from Competition Studies
inferred← citeshttps://doi.org/10.3390/antibiotics10070863openalex-snapshot
Role of RND Efflux Pumps in Drug Resistance of Cystic Fibrosis Pathogens
inferred← citeshttps://doi.org/10.3390/antibiotics11010030openalex-snapshot
Evaluation of Heterocyclic Carboxamides as Potential Efflux Pump Inhibitors in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.3390/antibiotics11010052openalex-snapshot
A Model for Allosteric Communication in Drug Transport by the AcrAB-TolC Tripartite Efflux Pump
inferred← citeshttps://doi.org/10.3390/antibiotics11020126openalex-snapshot
Molecular Determinants for OMF Selectivity in Tripartite RND Multidrug Efflux Systems
inferred← citeshttps://doi.org/10.3390/antibiotics11040520openalex-snapshot
Bacterial Multidrug Efflux Pumps at the Frontline of Antimicrobial Resistance: An Overview
inferred← citeshttps://doi.org/10.3390/antibiotics11060716openalex-snapshot
Evaluation of a Conformationally Constrained Indole Carboxamide as a Potential Efflux Pump Inhibitor in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.3390/antibiotics11091223openalex-snapshot
Evaluation of Catechin Synergistic and Antibacterial Efficacy on Biofilm Formation and acrA Gene Expression of Uropathogenic E. coli Clinical Isolates
inferred← citeshttps://doi.org/10.3390/antibiotics12111621openalex-snapshot
Resistance in Pseudomonas aeruginosa: A Narrative Review of Antibiogram Interpretation and Emerging Treatments
inferred← citeshttps://doi.org/10.3390/ijms22010050openalex-snapshot
Fake It ‘Till You Make It—The Pursuit of Suitable Membrane Mimetics for Membrane Protein Biophysics
inferred← citeshttps://doi.org/10.3390/ijms232415779openalex-snapshot
Role of Efflux Pumps on Antimicrobial Resistance in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.3390/ijms27114804openalex-snapshot
Medicinal Plants: A Promising Therapeutic Approach for Addressing Antimicrobial Resistance
inferred← citeshttps://doi.org/10.3390/membranes13060568openalex-snapshot
The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs
inferred← citeshttps://doi.org/10.3390/molecules24081487openalex-snapshot
Selenocompounds as Novel Antibacterial Agents and Bacterial Efflux Pump Inhibitors
inferred← citeshttps://doi.org/10.3390/toxics10100613openalex-snapshot
Unravelling the Portuguese Coastal and Transitional Waters’ Microbial Resistome as a Biomarker of Differential Anthropogenic Impact
inferred← citeshttps://doi.org/10.3410/f.727645461.793538819openalex-snapshot
Faculty Opinions recommendation of Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
inferred← citeshttps://doi.org/10.37256/amtt.4120232230openalex-snapshot
Antibacterial Properties of Metal and Metal Oxide Nanoparticles-An Overview
inferred← citeshttps://doi.org/10.5483/bmbrep.2023-0070openalex-snapshot
AcrAB-TolC, a major efflux pump in Gram negative bacteria: toward understanding its operation mechanism
inferred← citeshttps://doi.org/10.55691/2278-344x.1098openalex-snapshot
Nanomaterials to Transform Infection Control With Antimicrobial Solutions
inferred← citeshttps://doi.org/10.58837/chula.the.2018.529openalex-snapshot
Genome characterization of quinolone resistance associated genes of flavobacterium columnare isolated from columnaris diseased asian sea bass (lates calcarif)ER)
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