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Transcriptional regulation of hepatic lipogenesis

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cphy.c130024openalex-snapshot

Energy Metabolism in the Liver

inferredcites →https://doi.org/10.1002/hep.22887openalex-snapshot

Role of adenosine monophosphate‐activated protein kinase–p70 ribosomal S6 kinase‐1 pathway in repression of liver X receptor‐alpha–dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones†

inferredcites →https://doi.org/10.1007/s00125-013-2869-1openalex-snapshot

Insulin signalling mechanisms for triacylglycerol storage

inferredcites →https://doi.org/10.1016/b978-0-12-407766-9.00016-xopenalex-snapshot

Sirtuin 1 Deacetylase

inferredcites →https://doi.org/10.1016/j.bbrc.2010.10.113openalex-snapshot

The role of O-linked GlcNAc modification on the glucose response of ChREBP

inferredcites →https://doi.org/10.1016/j.cell.2008.07.002openalex-snapshot

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

inferredcites →https://doi.org/10.1016/j.cell.2008.12.040openalex-snapshot

A Role of DNA-PK for the Metabolic Gene Regulation in Response to Insulin

inferredcites →https://doi.org/10.1016/j.cell.2009.06.049openalex-snapshot

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

inferredcites →https://doi.org/10.1016/j.cell.2011.06.034openalex-snapshot

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

inferredcites →https://doi.org/10.1016/j.cell.2014.12.023openalex-snapshot

Ligand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity

inferredcites →https://doi.org/10.1016/j.cell.2015.03.015openalex-snapshot

Time for Food: The Intimate Interplay between Nutrition, Metabolism, and the Circadian Clock

inferredcites →https://doi.org/10.1016/j.cmet.2005.03.001openalex-snapshot

LXRs regulate the balance between fat storage and oxidation

inferredcites →https://doi.org/10.1016/j.cmet.2006.04.005openalex-snapshot

Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ

inferredcites →https://doi.org/10.1016/j.cmet.2006.11.012openalex-snapshot

Enzymatic Reduction of Oxysterols Impairs LXR Signaling in Cultured Cells and the Livers of Mice

inferredcites →https://doi.org/10.1016/j.cmet.2008.06.013openalex-snapshot

Genome-wide Coactivation Analysis of PGC-1α Identifies BAF60a as a Regulator of Hepatic Lipid Metabolism

inferredcites →https://doi.org/10.1016/j.cmet.2009.11.002openalex-snapshot

Circadian Clock-Coordinated 12 Hr Period Rhythmic Activation of the IRE1α Pathway Controls Lipid Metabolism in Mouse Liver

inferredcites →https://doi.org/10.1016/j.cmet.2011.06.002openalex-snapshot

Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways

inferredcites →https://doi.org/10.1016/j.cmet.2012.03.015openalex-snapshot

Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c

inferredcites →https://doi.org/10.1016/j.cmet.2013.04.021openalex-snapshot

Reciprocal Regulation of Hepatic and Adipose Lipogenesis by Liver X Receptors in Obesity and Insulin Resistance

inferredcites →https://doi.org/10.1016/j.cmet.2013.08.002openalex-snapshot

A Central Role for mTOR in Lipid Homeostasis

inferredcites →https://doi.org/10.1016/j.cmet.2014.03.027openalex-snapshot

Transcriptional Coregulators: Fine-Tuning Metabolism

inferredcites →https://doi.org/10.1016/j.coph.2010.08.004openalex-snapshot

Insulin signaling in fatty acid and fat synthesis: a transcriptional perspective

inferredcites →https://doi.org/10.1016/j.devcel.2008.11.013openalex-snapshot

ER Stress and Lipogenesis: A Slippery Slope toward Hepatic Steatosis

inferredcites →https://doi.org/10.1016/j.jhep.2011.07.019openalex-snapshot

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

inferredcites →https://doi.org/10.1016/j.molcel.2012.10.028openalex-snapshot

Phosphorylation and Recruitment of BAF60c in Chromatin Remodeling for Lipogenesis in Response to Insulin

inferredcites →https://doi.org/10.1016/j.molcel.2013.10.022openalex-snapshot

Deacetylase-Independent Function of HDAC3 in Transcription and Metabolism Requires Nuclear Receptor Corepressor

inferredcites →https://doi.org/10.1016/j.tem.2013.01.003openalex-snapshot

Novel insights into ChREBP regulation and function

inferredcites →https://doi.org/10.1016/s0021-9258(17)31298-xopenalex-snapshot

Hormonal Regulation of Mouse Fatty Acid Synthase Gene Transcription in Liver

inferredcites →https://doi.org/10.1016/s0021-9258(17)37507-5openalex-snapshot

Identification of an insulin response element in the fatty acid synthase promoter.

inferredcites →https://doi.org/10.1016/s0021-9258(18)31457-1openalex-snapshot

Carbohydrate regulation of the rat L-type pyruvate kinase gene requires two nuclear factors: LF-A1 and a member of the c-myc family

inferredcites →https://doi.org/10.1016/s0021-9258(18)54359-3openalex-snapshot

Transcriptional regulation of p90 with sequence homology to Escherichia coli glycerol-3-phosphate acyltransferase.

inferredcites →https://doi.org/10.1016/s0021-9258(18)75905-xopenalex-snapshot

A METHOD OF SEPARATING THE ANTERIOR PITUITARY-LIKE HORMONE FROM THE URINE OF PREGNANT WOMEN

inferredcites →https://doi.org/10.1016/s0092-8674(03)00929-2openalex-snapshot

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

inferredcites →https://doi.org/10.1021/cr5004248openalex-snapshot

New Facets in the Regulation of Gene Expression by ADP-Ribosylation and Poly(ADP-ribose) Polymerases

inferredcites →https://doi.org/10.1038/383728a0openalex-snapshot

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

inferredcites →https://doi.org/10.1038/nature05449openalex-snapshot

The nuclear receptor LXR is a glucose sensor

inferredcites →https://doi.org/10.1038/nature10986openalex-snapshot

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

inferredcites →https://doi.org/10.1038/nature11048openalex-snapshot

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

inferredcites →https://doi.org/10.1038/nature12710openalex-snapshot

A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use

inferredcites →https://doi.org/10.1038/ncomms2537openalex-snapshot

De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health

inferredcites →https://doi.org/10.1038/ncomms6190openalex-snapshot

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors

inferredcites →https://doi.org/10.1038/ng1320openalex-snapshot

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1)

inferredcites →https://doi.org/10.1042/bj20041514openalex-snapshot

A simple promoter containing two Sp1 sites controls the expression of sterol-regulatory-element-binding protein 1a (SREBP-1a)

inferredcites →https://doi.org/10.1042/bj20111280openalex-snapshot

Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes

inferredcites →https://doi.org/10.1073/pnas.0130116100openalex-snapshot

Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis

inferredcites →https://doi.org/10.1073/pnas.0308617100openalex-snapshot

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity

inferredcites →https://doi.org/10.1073/pnas.0401516101openalex-snapshot

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

inferredcites →https://doi.org/10.1073/pnas.0404297101openalex-snapshot

Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver

inferredcites →https://doi.org/10.1073/pnas.0730817100openalex-snapshot

Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver

inferredcites →https://doi.org/10.1073/pnas.0914798107openalex-snapshot

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

inferredcites →https://doi.org/10.1073/pnas.1213343109openalex-snapshot

Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase

inferredcites →https://doi.org/10.1073/pnas.180306597openalex-snapshot

Nutritional regulation of the fatty acid synthase promoter in vivo : Sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element

inferredcites →https://doi.org/10.1073/pnas.231370798openalex-snapshot

Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein

inferredcites →https://doi.org/10.1073/pnas.93.3.1049openalex-snapshot

Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid.

inferredcites →https://doi.org/10.1074/jbc.270.3.1416openalex-snapshot

Characterization of the Murine Mitochondrial Glycerol-3-phosphate Acyltransferase Promoter

inferredcites →https://doi.org/10.1074/jbc.270.48.28716openalex-snapshot

Upstream Stimulatory Factors Bind to Insulin Response Sequence of the Fatty Acid Synthase Promoter USF1 IS REGULATED

inferredcites →https://doi.org/10.1074/jbc.270.51.30339openalex-snapshot

Hormonal and Nutritional Control of the Fatty Acid Synthase Promoter in Transgenic Mice

inferredcites →https://doi.org/10.1074/jbc.272.35.21944openalex-snapshot

Glucose-dependent Liver Gene Expression in Upstream Stimulatory Factor 2 −/− Mice

inferredcites →https://doi.org/10.1074/jbc.272.42.26367openalex-snapshot

Upstream Stimulatory Factor Binding to the E-box at −65 Is Required for Insulin Regulation of the Fatty Acid Synthase Promoter

inferredcites →https://doi.org/10.1074/jbc.273.32.20175openalex-snapshot

Differential Roles of Upstream Stimulatory Factors 1 and 2 in the Transcriptional Response of Liver Genes to Glucose

inferredcites →https://doi.org/10.1074/jbc.273.39.25420openalex-snapshot

Insulin Stimulation of the Fatty Acid Synthase Promoter Is Mediated by the Phosphatidylinositol 3-Kinase Pathway

inferredcites →https://doi.org/10.1074/jbc.274.4.2009openalex-snapshot

Essential Role in Vivo of Upstream Stimulatory Factors for a Normal Dietary Response of the Fatty Acid Synthase Gene in the Liver

inferredcites →https://doi.org/10.1074/jbc.275.14.10121openalex-snapshot

Two 5′-Regions Are Required for Nutritional and Insulin Regulation of the Fatty-acid Synthase Promoter in Transgenic Mice

inferredcites →https://doi.org/10.1074/jbc.275.7.4726openalex-snapshot

Different Sterol Regulatory Element-binding Protein-1 Isoforms Utilize Distinct Co-regulatory Factors to Activate the Promoter for Fatty Acid Synthase

inferredcites →https://doi.org/10.1074/jbc.m005353200openalex-snapshot

Promoter Analysis of the Mouse Sterol Regulatory Element-binding Protein-1c Gene

inferredcites →https://doi.org/10.1074/jbc.m005425200openalex-snapshot

MAP Kinases Erk1/2 Phosphorylate Sterol Regulatory Element-binding Protein (SREBP)-1a at Serine 117 in Vitro

inferredcites →https://doi.org/10.1074/jbc.m107895200openalex-snapshot

Mechanism for Fatty Acid “Sparing” Effect on Glucose-induced Transcription

inferredcites →https://doi.org/10.1074/jbc.m109.022244openalex-snapshot

Hepatocyte Growth Factor Family Negatively Regulates Hepatic Gluconeogenesis via Induction of Orphan Nuclear Receptor Small Heterodimer Partner in Primary Hepatocytes

inferredcites →https://doi.org/10.1074/jbc.m109.082685openalex-snapshot

Nuclear Receptor Liver X Receptor Is O-GlcNAc-modified in Response to Glucose

inferredcites →https://doi.org/10.1074/jbc.m109771200openalex-snapshot

Liver X Receptors as Insulin-mediating Factors in Fatty Acid and Cholesterol Biosynthesis

inferredcites →https://doi.org/10.1074/jbc.m110.122978openalex-snapshot

SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism*

inferredcites →https://doi.org/10.1074/jbc.m111041200openalex-snapshot

Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors

inferredcites →https://doi.org/10.1074/jbc.m111421200openalex-snapshot

Diminished Hepatic Response to Fasting/Refeeding and Liver X Receptor Agonists in Mice with Selective Deficiency of Sterol Regulatory Element-binding Protein-1c

inferredcites →https://doi.org/10.1074/jbc.m112.386854openalex-snapshot

Identification of Akt-independent Regulation of Hepatic Lipogenesis by Mammalian Target of Rapamycin (mTOR) Complex 2

inferredcites →https://doi.org/10.1074/jbc.m112.418855openalex-snapshot

Structural Characterization of a Unique Interface between Carbohydrate Response Element-binding Protein (ChREBP) and 14-3-3β Protein

inferredcites →https://doi.org/10.1074/jbc.m114.567628openalex-snapshot

Liver Clock Protein BMAL1 Promotes de Novo Lipogenesis through Insulin-mTORC2-AKT Signaling

inferredcites →https://doi.org/10.1074/jbc.m114.573659openalex-snapshot

Regulation of Lipogenic Gene Expression by Lysine-specific Histone Demethylase-1 (LSD1)

inferredcites →https://doi.org/10.1074/jbc.m311301200openalex-snapshot

Mlx Is the Functional Heteromeric Partner of the Carbohydrate Response Element-binding Protein in Glucose Regulation of Lipogenic Enzyme Genes

inferredcites →https://doi.org/10.1074/jbc.m405522200openalex-snapshot

Regulatory Role of Glycogen Synthase Kinase 3 for Transcriptional Activity of ADD1/SREBP1c

inferredcites →https://doi.org/10.1074/jbc.m410509200openalex-snapshot

Ser1928 Is a Common Site for Cav1.2 Phosphorylation by Protein Kinase C Isoforms

inferredcites →https://doi.org/10.1074/jbc.m413063200openalex-snapshot

Direct Role of ChREBP·Mlx in Regulating Hepatic Glucose-responsive Genes

inferredcites →https://doi.org/10.1074/jbc.m414499200openalex-snapshot

The Tuberous Sclerosis Protein TSC2 Is Not Required for the Regulation of the Mammalian Target of Rapamycin by Amino Acids and Certain Cellular Stresses

inferredcites →https://doi.org/10.1074/jbc.m500801200openalex-snapshot

Diet-induced Obesity in C57BL/6J Mice Causes Increased Renal Lipid Accumulation and Glomerulosclerosis via a Sterol Regulatory Element-binding Protein-1c-dependent Pathway

inferredcites →https://doi.org/10.1074/jbc.m600272200openalex-snapshot

FoxO1 Regulates Multiple Metabolic Pathways in the Liver

inferredcites →https://doi.org/10.1074/jbc.m601576200openalex-snapshot

ChREBP•Mlx Is the Principal Mediator of Glucose-induced Gene Expression in the Liver

inferredcites →https://doi.org/10.1074/jbc.m605023200openalex-snapshot

The Liver X Receptor (LXR) and Hepatic Lipogenesis

inferredcites →https://doi.org/10.1074/jbc.m610566200openalex-snapshot

Direct Interaction between USF and SREBP-1c Mediates Synergistic Activation of the Fatty-acid Synthase Promoter

inferredcites →https://doi.org/10.1074/jbc.m611911200openalex-snapshot

Protein Kinase A Suppresses Sterol Regulatory Element-binding Protein-1C Expression via Phosphorylation of Liver X Receptor in the Liver

inferredcites →https://doi.org/10.1074/jbc.m702228200openalex-snapshot

Expression of the Rat Sterol Regulatory Element-binding Protein-1c Gene in Response to Insulin Is Mediated by Increased Transactivating Capacity of Specificity Protein 1 (Sp1)

inferredcites →https://doi.org/10.1074/jbc.m804308200openalex-snapshot

Regulation of Nuclear Import/Export of Carbohydrate Response Element-binding Protein (ChREBP)

inferredcites →https://doi.org/10.1074/jbc.m805746200openalex-snapshot

Insulin Enhances Post-translational Processing of Nascent SREBP-1c by Promoting Its Phosphorylation and Association with COPII Vesicles

inferredcites →https://doi.org/10.1074/jbc.r114.576355openalex-snapshot

Pathway-selective Insulin Resistance and Metabolic Disease: The Importance of Nutrient Flux

inferredcites →https://doi.org/10.1093/nar/gkt034openalex-snapshot

Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells

inferredcites →https://doi.org/10.1096/fj.12-208751openalex-snapshot

The nuclear receptor REV‐ERBα is required for the daily balance of carbohydrate and lipid metabolism

inferredcites →https://doi.org/10.1097/mol.0b013e328352dd03openalex-snapshot

Connecting mTORC1 signaling to SREBP-1 activation

inferredcites →https://doi.org/10.1101/gad.186858.112openalex-snapshot

Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function

inferredcites →https://doi.org/10.1101/gad.1901210openalex-snapshot

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP

inferredcites →https://doi.org/10.1101/gad.8.5.538openalex-snapshot

Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors.

inferredcites →https://doi.org/10.1101/gad.844900openalex-snapshot

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

inferredcites →https://doi.org/10.1101/gad.850400openalex-snapshot

Role of LXRs in control of lipogenesis

inferredcites →https://doi.org/10.1113/jphysiol.2006.108506openalex-snapshot

Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

inferredcites →https://doi.org/10.1126/science.1127196openalex-snapshot

A Topoisomerase IIß-Mediated dsDNA Break Required for Regulated Transcription

inferredcites →https://doi.org/10.1126/science.1129808openalex-snapshot

Gene Expression Needs a Break to Unwind Before Carrying On

inferredcites →https://doi.org/10.1126/science.1198125openalex-snapshot

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

inferredcites →https://doi.org/10.1128/mcb.01166-13openalex-snapshot

PIASy-Mediated Sumoylation of SREBP1c Regulates Hepatic Lipid Metabolism upon Fasting Signaling

inferredcites →https://doi.org/10.1128/mcb.13.12.7725openalex-snapshot

Functional Characterization of the L-Type Pyruvate Kinase Gene Glucose Response Complex

inferredcites →https://doi.org/10.1128/mcb.13.8.4753openalex-snapshot

ADD1: a Novel Helix-Loop-Helix Transcription Factor Associated with Adipocyte Determination and Differentiation

inferredcites →https://doi.org/10.1128/mcb.15.5.2582openalex-snapshot

Dual DNA Binding Specificity of ADD1/SREBP1 Controlled by a Single Amino Acid in the Basic Helix-Loop-Helix Domain

inferredcites →https://doi.org/10.1128/mcb.17.9.5193openalex-snapshot

Promoter Selective Transcriptional Synergy Mediated by Sterol Regulatory Element Binding Protein and Sp1: a Critical Role for the Btd Domain of Sp1

inferredcites →https://doi.org/10.1128/mcb.21.9.2991-3000.2001openalex-snapshot

Identification of Liver X Receptor-Retinoid X Receptor as an Activator of the Sterol Regulatory Element-Binding Protein 1c Gene Promoter

inferredcites →https://doi.org/10.1128/mcb.23.16.5780-5789.2003openalex-snapshot

Promoter-Specific Roles for Liver X Receptor/Corepressor Complexes in the Regulation of ABCA1 and SREBP1 Gene Expression

inferredcites →https://doi.org/10.1128/mcb.23.16.5896-5907.2003openalex-snapshot

Occupancy and Function of the −150 Sterol Regulatory Element and −65 E-Box in Nutritional Regulation of the Fatty Acid Synthase Gene in Living Animals

inferredcites →https://doi.org/10.1146/annurev.nutr.17.1.325openalex-snapshot

MECHANISMS BY WHICH CARBOHYDRATES REGULATE EXPRESSION OF GENES FOR GLYCOLYTIC AND LIPOGENIC ENZYMES

inferredcites →https://doi.org/10.1146/annurev.nutr.18.1.331openalex-snapshot

NUTRITIONAL AND HORMONAL REGULATION OF ENZYMES IN FAT SYNTHESIS: Studies of Fatty Acid Synthase and Mitochondrial Glycerol-3-Phosphate Acyltransferase Gene Transcription

inferredcites →https://doi.org/10.1152/ajpcell.00374.2005openalex-snapshot

Sterol regulatory element-binding protein 1 is negatively modulated by PKA phosphorylation

inferredcites →https://doi.org/10.1152/physiolgenomics.00206.2010openalex-snapshot

Transcriptional profiling reveals a role for RORα in regulating gene expression in obesity-associated inflammation and hepatic steatosis

inferredcites →https://doi.org/10.1172/jci119248openalex-snapshot

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

inferredcites →https://doi.org/10.1172/jci119746openalex-snapshot

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

inferredcites →https://doi.org/10.1172/jci1411openalex-snapshot

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

inferredcites →https://doi.org/10.1172/jci18816openalex-snapshot

PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity

inferredcites →https://doi.org/10.1172/jci34314openalex-snapshot

ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver

inferredcites →https://doi.org/10.1172/jci41624openalex-snapshot

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

inferredcites →https://doi.org/10.1172/jci41636openalex-snapshot

The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

inferredcites →https://doi.org/10.1194/jlr.m049130openalex-snapshot

Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity

inferredcites →https://doi.org/10.1210/er.2015-1007openalex-snapshot

Circadian Metabolism in the Light of Evolution

inferredcites →https://doi.org/10.1210/me.2005-0057openalex-snapshot

The Orphan Nuclear Receptor Rev-erbα Recruits the N-CoR/Histone Deacetylase 3 Corepressor to Regulate the Circadian Bmal1 Gene

inferredcites →https://doi.org/10.1210/me.2007-0560openalex-snapshot

Glucose-Mediated Transactivation of Carbohydrate Response Element-Binding Protein Requires Cooperative Actions from Mondo Conserved Regions and Essential Trans -Acting Factor 14-3-3

inferredcites →https://doi.org/10.1210/me.2008-0012openalex-snapshot

Activating Signal Cointegrator-2 Is an Essential Adaptor to Recruit Histone H3 Lysine 4 Methyltransferases MLL3 and MLL4 to the Liver X Receptors

inferredcites →https://doi.org/10.1371/journal.pone.0032609openalex-snapshot

Preventing Phosphorylation of Sterol Regulatory Element-Binding Protein 1a by MAP-Kinases Protects Mice from Fatty Liver and Visceral Obesity

inferredcites →https://doi.org/10.15252/embj.201591385openalex-snapshot

The transcription factor Cabut coordinates energy metabolism and the circadian clock in response to sugar sensing

inferredcites →https://doi.org/10.2337/db05-0822openalex-snapshot

Glucose-Dependent Transcriptional Regulation by an Evolutionarily Conserved Glucose-Sensing Module

inferredcites →https://doi.org/10.2337/db06-0200openalex-snapshot

Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in ob/ob Mice

inferredcites →https://doi.org/10.2337/db10-0452openalex-snapshot

O -GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver

inferredcites →https://doi.org/10.4161/cc.8.13.8941openalex-snapshot

DNA-PK: Relaying the insulin signal to USF in lipogenesis

inferredcites →https://doi.org/10.4161/cc.8.13.9024openalex-snapshot

Wnt asymmetry and the terminal division of neuronal progenitors

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4350587openalex-extracted

GPX4 Transcriptionally Promotes Hepatocellular Carcinoma Metastasis via GRHL3/PI3K/AKT Axis

inferred← citeshttps://doi.org/10.1002/1873-3468.12197openalex-snapshot

Site‐specific cleavage of acetoacetyl‐CoA synthetase by legumain

inferred← citeshttps://doi.org/10.1002/1873-3468.13538openalex-snapshot

Chronic exposure to Pb2+ perturbs Ch REBP transactivation and coerces hepatic dyslipidemia

inferred← citeshttps://doi.org/10.1002/9781119060208.ch3openalex-snapshot

From Cellular Mechanisms to Physiological Responses

inferred← citeshttps://doi.org/10.1002/9781119436812.ch22openalex-snapshot

Lipoprotein Metabolism and Cholesterol Balance

inferred← citeshttps://doi.org/10.1002/9781119436812.ch39openalex-snapshot

Insulin‐Mediated PI3K and AKT Signaling

inferred← citeshttps://doi.org/10.1002/9781119436812.ch7openalex-snapshot

The Hepatocellular Secretory Pathway

inferred← citeshttps://doi.org/10.1002/advs.202411368openalex-snapshot

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

inferred← citeshttps://doi.org/10.1002/advs.202412233openalex-snapshot

SREBP1c‐Mediated Transcriptional Repression of YME1L1 Contributes to Acute Kidney Injury by Inducing Mitochondrial Dysfunction in Tubular Epithelial Cells

inferred← citeshttps://doi.org/10.1002/advs.75915openalex-snapshot

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

inferred← citeshttps://doi.org/10.1002/cac2.12360openalex-snapshot

Lipid metabolism in pancreatic cancer: emerging roles and potential targets

inferred← citeshttps://doi.org/10.1002/cbin.11666openalex-snapshot

CTRP1 decreases ABCA1 expression and promotes lipid accumulation through the miR‐424‐5p/FoxO1 pathway in THP‐1 macrophage‐derived foam cells

inferred← citeshttps://doi.org/10.1002/dmrr.70029openalex-snapshot

The Rise of Type 2 Diabetes in Children and Adolescents: An Emerging Pandemic

inferred← citeshttps://doi.org/10.1002/ejlt.202300105openalex-snapshot

Walnut fruit diaphragm ethanol extract ameliorates damage due to Triton WR‐1339‐induced hyperlipidemia in rats

inferred← citeshttps://doi.org/10.1002/fsn3.3856openalex-snapshot

Antiobesity effect of healthy food crops and functional foods: A systematic review of their mechanisms

inferred← citeshttps://doi.org/10.1002/fsn3.72362openalex-snapshot

Effects of Short‐Term Energy Limitation at Different Levels With Normal Protein Intake on Hepatic Lipid Metabolism and the Gut Microbiota in Overweight/Obese Mice

inferred← citeshttps://doi.org/10.1002/hep.31296openalex-snapshot

Thyroid Hormone Signaling and the Liver

inferred← citeshttps://doi.org/10.1002/hep4.1256openalex-snapshot

FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice

inferred← citeshttps://doi.org/10.1002/hep4.1362openalex-snapshot

Repression of MicroRNA‐30e by Hepatitis C Virus Enhances Fatty Acid Synthesis

inferred← citeshttps://doi.org/10.1002/iub.2014openalex-snapshot

3,5‐diiodo‐L‐thyronine increases de novo lipogenesis in liver from hypothyroid rats by SREBP‐1 and ChREBP‐mediated transcriptional mechanisms

inferred← citeshttps://doi.org/10.1002/jez.70113openalex-snapshot

Exposure to Dim Light at Night Impairs Photoperiodic and Metabolic Gene Expression in Syrian Hamsters ( Mesocricetus auratus )

inferred← citeshttps://doi.org/10.1002/mnfr.201700433openalex-snapshot

Identification of Signaling Pathways Targeted by the Food Contaminant FB1: Transcriptome and Kinome Analysis of Samples from Pig Liver and Intestine

inferred← citeshttps://doi.org/10.1002/mnfr.202000965openalex-snapshot

Sex‐Specific Effects of Myo‐Inositol Ingested During Lactation in the Improvement of Metabolic Health in Adult Rats

inferred← citeshttps://doi.org/10.1002/oby.22061openalex-snapshot

Lithospermum erythrorhizon Root and its Naphthoquinones Repress SREBP1c and Activate PGC1α Through AMPKα

inferred← citeshttps://doi.org/10.1002/oby.22152openalex-snapshot

Food Restriction is Required to Preserve the Antisteatotic Effects of Central Leptin in the Liver of Middle‐Aged Rats

inferred← citeshttps://doi.org/10.1007/164_2020_352openalex-snapshot

Nonalcoholic Fatty Liver Disease

inferred← citeshttps://doi.org/10.1007/16833_2022_43openalex-snapshot

Metabolic Alterations of Hepatocellular Cancer Stem Cells

inferred← citeshttps://doi.org/10.1007/978-1-4471-4715-2_9openalex-snapshot

Nonalcoholic Fatty Liver Disease

inferred← citeshttps://doi.org/10.1007/978-3-030-12668-1_3openalex-snapshot

Current Models of Fatty Liver Disease; New Insights, Therapeutic Targets and Interventions

inferred← citeshttps://doi.org/10.1007/978-3-030-49476-6_13openalex-snapshot

Targeting Metabolism

inferred← citeshttps://doi.org/10.1007/978-3-031-63657-8_7openalex-snapshot

Protein Kinases in Obesity, and the Kinase-Targeted Therapy

inferred← citeshttps://doi.org/10.1007/978-3-319-27317-4_1-1openalex-snapshot

Overview of Glucose Homeostasis

inferred← citeshttps://doi.org/10.1007/978-981-15-6082-8_4openalex-snapshot

Microsomal Triglyceride Transfer Protein: From Lipid Metabolism to Metabolic Diseases

inferred← citeshttps://doi.org/10.1007/s00018-019-03092-7openalex-snapshot

Palmitic acid is an intracellular signaling molecule involved in disease development

inferred← citeshttps://doi.org/10.1007/s00018-023-04820-wopenalex-snapshot

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN

inferred← citeshttps://doi.org/10.1007/s00125-023-05878-8openalex-snapshot

Tcf7l2 in hepatocytes regulates de novo lipogenesis in diet-induced non-alcoholic fatty liver disease in mice

inferred← citeshttps://doi.org/10.1007/s00394-017-1599-4openalex-snapshot

Supplementation with an insoluble fiber obtained from carob pod (Ceratonia siliqua L.) rich in polyphenols prevents dyslipidemia in rabbits through SIRT1/PGC-1α pathway

inferred← citeshttps://doi.org/10.1007/s00439-024-02654-5openalex-snapshot

Integrative regulation of hLMR1 by dietary and genetic factors in nonalcoholic fatty liver disease and hyperlipidemia

inferred← citeshttps://doi.org/10.1007/s10068-024-01664-3openalex-snapshot

Fatty acids and epigenetics in health and diseases

inferred← citeshttps://doi.org/10.1007/s10545-018-0176-1openalex-snapshot

Medium‐chain triglycerides supplement therapy with a low‐carbohydrate formula can supply energy and enhance ammonia detoxification in the hepatocytes of patients with adult–onset type II citrullinemia

inferred← citeshttps://doi.org/10.1007/s10565-024-09925-xopenalex-snapshot

ASPP2 deficiency attenuates lipid accumulation through the PPARγ pathway in alcoholic liver injury

inferred← citeshttps://doi.org/10.1007/s10616-023-00614-xopenalex-snapshot

LncRNA HOTAIR accelerates free fatty acid-induced inflammatory response in HepG2 cells by recruiting SRSF1 to stabilize MLXIPL mRNA

inferred← citeshttps://doi.org/10.1007/s10735-026-11000-0openalex-snapshot

Apigenin attenuates MASLD progression by suppressing lipogenesis and macrophage M1-like inflammatory activation: involvement of SMAD4-associated signaling

inferred← citeshttps://doi.org/10.1007/s10753-023-01820-7openalex-snapshot

NF-κB-Inducing Kinase Provokes Insulin Resistance in Skeletal Muscle of Obese Mice

inferred← citeshttps://doi.org/10.1007/s10753-024-02086-3openalex-snapshot

Ginkgolide C attenuated Western diet-induced non-alcoholic fatty liver disease via increasing AMPK activation

inferred← citeshttps://doi.org/10.1007/s11033-020-05352-3openalex-snapshot

Dysregulated lipid metabolism in hepatocellular carcinoma cancer stem cells

inferred← citeshttps://doi.org/10.1007/s11064-018-2492-0openalex-snapshot

Impact of Coffee and Cacao Purine Metabolites on Neuroplasticity and Neurodegenerative Disease

inferred← citeshttps://doi.org/10.1007/s11596-019-2104-5openalex-snapshot

Curcumin Recovers Intracellular Lipid Droplet Formation Through Increasing Perilipin 5 Gene Expression in Activated Hepatic Stellate Cells In Vitro

inferred← citeshttps://doi.org/10.1007/s11883-018-0715-0openalex-snapshot

The Interplay of Lipids, Lipoproteins, and Immunity in Atherosclerosis

inferred← citeshttps://doi.org/10.1007/s11883-026-01444-wopenalex-snapshot

Dietary Interventions for Hypertriglyceridemia

inferred← citeshttps://doi.org/10.1007/s11892-020-01336-6openalex-snapshot

Dyslipidemia in Pediatric Type 2 Diabetes Mellitus

inferred← citeshttps://doi.org/10.1007/s11901-023-00596-6openalex-snapshot

Nutrition in Viral Hepatitis

inferred← citeshttps://doi.org/10.1007/s11908-017-0578-5openalex-snapshot

Hepatitis C Virus-Genotype 3: Update on Current and Emergent Therapeutic Interventions

inferred← citeshttps://doi.org/10.1007/s12011-021-03027-zopenalex-snapshot

Oral Subacute Exposure to Cadmium LOAEL Dose Induces Insulin Resistance and Impairment of the Hormonal and Metabolic Liver-Adipose Axis in Wistar Rats

inferred← citeshttps://doi.org/10.1007/s12020-023-03439-yopenalex-snapshot

Endothelium dysfunction and thrombosis in COVID-19 with type 2 diabetes

inferred← citeshttps://doi.org/10.1007/s12325-016-0306-9openalex-snapshot

The Role of Nuclear Receptors in the Pathophysiology, Natural Course, and Drug Treatment of NAFLD in Humans

inferred← citeshttps://doi.org/10.1007/s13105-021-00870-5openalex-snapshot

A novel therapeutic strategy for atherosclerosis: autophagy-dependent cholesterol efflux

inferred← citeshttps://doi.org/10.1007/s13105-024-01018-xopenalex-snapshot

TNFAIP1 promotes macrophage lipid accumulation and accelerates the development of atherosclerosis through the LEENE/FoxO1/ABCA1 pathway

inferred← citeshttps://doi.org/10.1007/s13105-025-01125-3openalex-snapshot

Malnutrition induces steatohepatitis by impairing hepatic lipid metabolism, mitochondrial function and the gut-liver axis

inferred← citeshttps://doi.org/10.1007/s13205-026-04837-5openalex-snapshot

From nutrients to health outcomes: integrating diet, disease risk, and lifelong wellness

inferred← citeshttps://doi.org/10.1007/s13238-017-0409-3openalex-snapshot

mTORC1 signaling in hepatic lipid metabolism

inferred← citeshttps://doi.org/10.1007/s13300-025-01734-7openalex-snapshot

Comprehending the Epidemiology and Aetiology of Childhood Obesity: Integrating Life Course Approaches for Prevention and Intervention

inferred← citeshttps://doi.org/10.1007/s13410-022-01050-xopenalex-snapshot

Role of ChREBP and SREBP-1c in gestational diabetes: two key players in glucose and lipid metabolism

inferred← citeshttps://doi.org/10.1007/s40124-025-00349-7openalex-snapshot

Pediatric Hypertriglyceridemia: Lipoprotein Metabolism, Etiology, and Management

inferred← citeshttps://doi.org/10.1007/s42764-022-00078-xopenalex-snapshot

MicroRNA-mediated reprogramming of glucose, fatty acid and amino acid metabolism in cancer

inferred← citeshttps://doi.org/10.1016/b978-0-08-102922-0.00003-1openalex-snapshot

Lipid metabolism: Normal physiology, dysregulation under obesity and diabetes, and therapeutic targets

inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.95802-1openalex-snapshot

Insulin Action; Post-Receptor Mechanisms

inferred← citeshttps://doi.org/10.1016/b978-0-12-804572-5.00059-8openalex-snapshot

Nutrients and Gene Expression in Type 2 Diabetes

inferred← citeshttps://doi.org/10.1016/b978-0-12-817067-0.00003-8openalex-snapshot

Antiobese properties of carotenoids: An overview of underlying molecular mechanisms

inferred← citeshttps://doi.org/10.1016/b978-0-443-13825-6.00395-2openalex-snapshot

Insulin Action; Post-Receptor Mechanisms

inferred← citeshttps://doi.org/10.1016/b978-2-294-76753-1.00033-3openalex-snapshot

Stockage et mobilisation des graisses dans le tissu adipeux blanc

inferred← citeshttps://doi.org/10.1016/bs.pmbts.2022.07.008openalex-snapshot

Endocytosis of LXRs: Signaling in liver and disease

inferred← citeshttps://doi.org/10.1016/j.addr.2017.05.017openalex-snapshot

Therapeutic pro-fibrogenic signaling pathways in fibroblasts

inferred← citeshttps://doi.org/10.1016/j.aninu.2022.10.005openalex-snapshot

Developmental changes in lipid and fatty acid metabolism and the inhibition by in ovo feeding oleic acid in Muscovy duck embryogenesis

inferred← citeshttps://doi.org/10.1016/j.aninu.2025.05.013openalex-snapshot

Integrating bile acid metabolism into precision nutrition strategies for improved swine performance

inferred← citeshttps://doi.org/10.1016/j.apsb.2024.02.025openalex-snapshot

Transcription factor EHF interacting with coactivator AJUBA aggravates malignancy and acts as a therapeutic target for gastroesophageal adenocarcinoma

inferred← citeshttps://doi.org/10.1016/j.aqrep.2025.102921openalex-snapshot

Effects of different carbohydrate levels on glycolipid metabolism and liver health of channel catfish (Ictalurus punctatus)

inferred← citeshttps://doi.org/10.1016/j.aquatox.2017.01.014openalex-snapshot

Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153

inferred← citeshttps://doi.org/10.1016/j.archoralbio.2018.10.003openalex-snapshot

Role and mechanism of the nod-like receptor family pyrin domain-containing 3 inflammasome in oral disease

inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2024.117508openalex-snapshot

Insulin resistance potentiates the effect of remnant cholesterol on cardiovascular mortality in individuals without diabetes

inferred← citeshttps://doi.org/10.1016/j.bbadis.2016.11.029openalex-snapshot

The transcription factor carbohydrate-response element-binding protein (ChREBP): A possible link between metabolic disease and cancer

inferred← citeshttps://doi.org/10.1016/j.bbadis.2017.02.019openalex-snapshot

The biochemical alterations underlying post-burn hypermetabolism

inferred← citeshttps://doi.org/10.1016/j.bbadis.2017.10.003openalex-snapshot

Farnesoid X receptor: A “homeostat” for hepatic nutrient metabolism

inferred← citeshttps://doi.org/10.1016/j.bbadis.2020.165688openalex-snapshot

Molecular changes in hepatic metabolism in ZDSD rats–A new polygenic rodent model of obesity, metabolic syndrome, and diabetes

inferred← citeshttps://doi.org/10.1016/j.bbadis.2021.166249openalex-snapshot

SIRT6 controls hepatic lipogenesis by suppressing LXR, ChREBP, and SREBP1

inferred← citeshttps://doi.org/10.1016/j.bbadis.2025.167659openalex-snapshot

Insights on post-translational modifications in fatty liver and fibrosis progression

inferred← citeshttps://doi.org/10.1016/j.bbagrm.2021.194724openalex-snapshot

Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding

inferred← citeshttps://doi.org/10.1016/j.bbalip.2019.04.015openalex-snapshot

Phosphorylation dependent proteostasis of sterol regulatory element binding proteins

inferred← citeshttps://doi.org/10.1016/j.bbalip.2019.08.001openalex-snapshot

The fate of medium-chain fatty acids in very long-chain acyl‑CoA dehydrogenase deficiency (VLCADD): A matter of sex?

inferred← citeshttps://doi.org/10.1016/j.bbalip.2019.158582openalex-snapshot

A high-fat diet enriched in medium chain triglycerides triggers hepatic thermogenesis and improves metabolic health in lean and obese mice

inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.12.129openalex-snapshot

Histone modifications in FASN modulated by sterol regulatory element-binding protein 1c and carbohydrate responsive-element binding protein under insulin stimulation are related to NAFLD

inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.11.022openalex-snapshot

Fucoxanthin attenuates fatty acid-induced lipid accumulation in FL83B hepatocytes through regulated Sirt1/AMPK signaling pathway

inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.03.052openalex-snapshot

Enoyl coenzyme A hydratase 1 protects against high-fat-diet-induced hepatic steatosis and insulin resistance

inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.04.134openalex-snapshot

p62/mTOR/LXRα pathway inhibits cholesterol efflux mediated by ABCA1 and ABCG1 during autophagy blockage

inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.151314openalex-snapshot

Proline enhances the hepatic induction of lipogenic gene expression in male hepatic fasn reporter mice

inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152266openalex-snapshot

Laminin γ2 accelerates non-alcoholic fatty liver disease progression by enhancing lipid accumulation and fibrogenesis in hepatocytes

inferred← citeshttps://doi.org/10.1016/j.bcp.2016.10.016openalex-snapshot

Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation

inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114581openalex-snapshot

An octimibate derivative, Oxa17, enhances cholesterol efflux and exerts anti-inflammatory and atheroprotective effects in experimental atherosclerosis

inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116518openalex-snapshot

Piperlongumine, a natural alkaloid from Piper longum L. ameliorates metabolic-associated fatty liver disease by antagonizing the thromboxane A2 receptor

inferred← citeshttps://doi.org/10.1016/j.biopha.2017.04.130openalex-snapshot

Genistein has beneficial effects on hepatic steatosis in high fat-high sucrose diet-treated rats

inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113577openalex-snapshot

A new perspective on NAFLD: Focusing on the crosstalk between peroxisome proliferator-activated receptor alpha (PPARα) and farnesoid X receptor (FXR)

inferred← citeshttps://doi.org/10.1016/j.burnso.2020.02.001openalex-snapshot

Burn injury insulin resistance and central nervous system complications: A review

inferred← citeshttps://doi.org/10.1016/j.canlet.2019.11.032openalex-snapshot

SPIN1 triggers abnormal lipid metabolism and enhances tumor growth in liver cancer

inferred← citeshttps://doi.org/10.1016/j.cbi.2018.05.014openalex-snapshot

Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway

inferred← citeshttps://doi.org/10.1016/j.cbi.2022.110250openalex-snapshot

Isosilybin regulates lipogenesis and fatty acid oxidation via the AMPK/SREBP-1c/PPARα pathway

inferred← citeshttps://doi.org/10.1016/j.cca.2019.09.009openalex-snapshot

Circulating ectodysplasin A is a potential biomarker for nonalcoholic fatty liver disease

inferred← citeshttps://doi.org/10.1016/j.ccmp.2022.100050openalex-snapshot

Yunpi Qushi Jiangzhuo Recipe Alleviates Lipid Deposition and Reduces Liver Damage in Mice with Non-alcoholic Fatty Liver Disease

inferred← citeshttps://doi.org/10.1016/j.cdnut.2024.104510openalex-snapshot

Fructose Consumption in Pregnancy and Associations with Maternal and Offspring Hepatic and Whole-Body Adiposity in Rodents: A Scoping Review

inferred← citeshttps://doi.org/10.1016/j.cell.2017.04.001openalex-snapshot

AKT/PKB Signaling: Navigating the Network

inferred← citeshttps://doi.org/10.1016/j.cell.2023.11.043openalex-snapshot

A multi-tissue metabolome atlas of primate pregnancy

inferred← citeshttps://doi.org/10.1016/j.cellsig.2017.12.005openalex-snapshot

Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance

inferred← citeshttps://doi.org/10.1016/j.celrep.2020.107835openalex-snapshot

Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice

inferred← citeshttps://doi.org/10.1016/j.celrep.2020.108624openalex-snapshot

Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution

inferred← citeshttps://doi.org/10.1016/j.celrep.2021.110267openalex-snapshot

Lipid droplet dynamics regulate adult muscle stem cell fate

inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111071openalex-snapshot

RPA1 controls chromatin architecture and maintains lipid metabolic homeostasis

inferred← citeshttps://doi.org/10.1016/j.cels.2018.05.013openalex-snapshot

In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver

inferred← citeshttps://doi.org/10.1016/j.clinre.2017.10.005openalex-snapshot

A new pathway to eSCAPe lipotoxicity

inferred← citeshttps://doi.org/10.1016/j.cmet.2017.10.008openalex-snapshot

Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

inferred← citeshttps://doi.org/10.1016/j.cmet.2018.01.005openalex-snapshot

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans

inferred← citeshttps://doi.org/10.1016/j.cmet.2018.02.021openalex-snapshot

AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity

inferred← citeshttps://doi.org/10.1016/j.cmet.2024.07.014openalex-snapshot

Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11

inferred← citeshttps://doi.org/10.1016/j.cmet.2026.07.001openalex-snapshot

Competitive catabolism drives hyperglycemia and hyperinsulinemia in obesity

inferred← citeshttps://doi.org/10.1016/j.compbiolchem.2026.109039openalex-snapshot

DoTT-ML: Condition-aware detection of transcriptional readthrough from RNA-seq with optional ML-based prioritization

inferred← citeshttps://doi.org/10.1016/j.compbiomed.2026.111886openalex-snapshot

Quantitative modeling of insulin signaling reveals mechanisms of insulin resistance in obese mice

inferred← citeshttps://doi.org/10.1016/j.crfs.2020.03.008openalex-snapshot

Piceatannol attenuates fat accumulation and oxidative stress in steatosis-induced HepG2 cells

inferred← citeshttps://doi.org/10.1016/j.cub.2022.03.038openalex-snapshot

Enhanced lipogenesis through Pparγ helps cavefish adapt to food scarcity

inferred← citeshttps://doi.org/10.1016/j.diabres.2021.109027openalex-snapshot

Renal lipid accumulation induced by high-fat diet regulates glucose homeostasis via sodium-glucose cotransporter 2

inferred← citeshttps://doi.org/10.1016/j.diabres.2022.109977openalex-snapshot

One-hour post-load glucose is associated with severity of hepatic fibrosis risk

inferred← citeshttps://doi.org/10.1016/j.dnarep.2016.10.004openalex-snapshot

DNA-PKcs: A promising therapeutic target in human hepatocellular carcinoma?

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2019.109406openalex-snapshot

Linking chemical exposure to lipid homeostasis: A municipal waste water treatment plant influent is obesogenic for zebrafish larvae

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.117169openalex-snapshot

T-2 toxin triggers lipid metabolism disorder and oxidative stress in liver of ducks

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.119330openalex-snapshot

Association between urinary organophosphate pesticide metabolites and blood lipid levels in US children

inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.12.069openalex-snapshot

Design, synthesis, and biological evaluation of novel catecholopyrimidine based PDE4 inhibitor for the treatment of atopic dermatitis

inferred← citeshttps://doi.org/10.1016/j.ejmech.2020.112793openalex-snapshot

Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors

inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114405openalex-snapshot

Recent advances in natural anti-obesity compounds and derivatives based on in vivo evidence: A mini-review

inferred← citeshttps://doi.org/10.1016/j.ejmech.2025.117956openalex-snapshot

HSQC-guided discovery and structural optimization of antiadipogenic indole diterpenoids from endophytic fungus Penicillium janthinellum H-6

inferred← citeshttps://doi.org/10.1016/j.ejphar.2022.175066openalex-snapshot

Chloroquine modulates the sulforaphane anti-obesity mechanisms in a high-fat diet model: Role of JAK-2/ STAT-3/ SOCS-3 pathway

inferred← citeshttps://doi.org/10.1016/j.exger.2025.112952openalex-snapshot

Lipoprotein metabolism and its impact on life expectancy

inferred← citeshttps://doi.org/10.1016/j.fct.2022.112948openalex-snapshot

Tectorigenin ameliorated high-fat diet-induced nonalcoholic fatty liver disease through anti-inflammation and modulating gut microbiota in mice

inferred← citeshttps://doi.org/10.1016/j.fct.2024.114790openalex-snapshot

Chlormequat chloride induces hepatic steatosis by promoting mTOR/SREBP1 mediated lipogenesis via AMPK inhibition

inferred← citeshttps://doi.org/10.1016/j.foodres.2021.110539openalex-snapshot

The anti-obesogenic effects of dietary berry fruits: A review

inferred← citeshttps://doi.org/10.1016/j.foodres.2022.112008openalex-snapshot

Clitoria ternatea blue petal extract protects against obesity, oxidative stress, and inflammation induced by a high-fat, high-fructose diet in C57BL/6 mice

inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.06.019openalex-snapshot

Berberine attenuates nonalcoholic hepatic steatosis through the AMPK-SREBP-1c-SCD1 pathway

inferred← citeshttps://doi.org/10.1016/j.fshw.2022.06.001openalex-snapshot

A review on mechanisms of action of bioactive peptides against glucose intolerance and insulin resistance

inferred← citeshttps://doi.org/10.1016/j.fshw.2022.06.012openalex-snapshot

A soy glycinin derived octapeptide protects against MCD diet induced non-alcoholic fatty liver disease in mice

inferred← citeshttps://doi.org/10.1016/j.gene.2024.148407openalex-snapshot

Transcriptomic regulatory analysis of skeletal muscle development in landrace pigs

inferred← citeshttps://doi.org/10.1016/j.ghir.2020.101332openalex-snapshot

Growth hormone ameliorates high glucose-induced steatosis on in vitro cultured human HepG2 hepatocytes by inhibiting de novo lipogenesis via ChREBP and FAS suppression

inferred← citeshttps://doi.org/10.1016/j.hbpd.2025.04.007openalex-snapshot

The outcomes and mechanisms of chronic hepatitis B complicated by metabolic dysfunction-associated steatotic liver disease

inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e19034openalex-snapshot

Long noncoding RNA HOXC-AS3 remodels lipid metabolism and promotes the proliferation of transformed macrophages in the glioma stem cell microenvironment by regulating the hnRNPA1/CaM axis

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e29367openalex-snapshot

Gkongensin A, an HSP90β inhibitor, improves hyperlipidemia, hepatic steatosis, and insulin resistance

inferred← citeshttps://doi.org/10.1016/j.hnm.2023.200210openalex-snapshot

Visceral fat: A key mediator of NAFLD development and progression

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.130961openalex-snapshot

Regulation of lipid metabolism by E3 ubiquitin ligases in lipid-associated metabolic diseases

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.145642openalex-snapshot

A new target for curcumin in the treatment of non-alcoholic fatty liver disease: the FTO protein

inferred← citeshttps://doi.org/10.1016/j.impact.2020.100259openalex-snapshot

Hepatic impacts of gold nanoparticles with different surface coatings as revealed by assessing the hepatic drug-metabolizing enzyme and lipid homeostasis in mice

inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111444openalex-snapshot

LncRNA Gm28382 promotes lipogenesis by interacting with miR-326-3p to regulate ChREBP signaling pathway in NAFLD

inferred← citeshttps://doi.org/10.1016/j.intimp.2026.117083openalex-snapshot

Ark shell-derived oligopeptides attenuate hepatic steatosis in oleic acid induced HepG2 cell and high-fat diet induced mice

inferred← citeshttps://doi.org/10.1016/j.isci.2023.107128openalex-snapshot

Metabolic regulation of CTCF expression and chromatin association dictates starvation response in mice and flies

inferred← citeshttps://doi.org/10.1016/j.isci.2023.108226openalex-snapshot

TRPV4 enhances the synthesis of fatty acids to drive the progression of ovarian cancer through the calcium-mTORC1/SREBP1 signaling pathway

inferred← citeshttps://doi.org/10.1016/j.jare.2024.12.047openalex-snapshot

Dimeric guaianolide sesquiterpenoids from the flowers of Chrysanthemum indicum ameliorate hepatic steatosis through mitigating SIRT1-mediated lipid accumulation and ferroptosis

inferred← citeshttps://doi.org/10.1016/j.jbc.2021.100714openalex-snapshot

NF-κB p65 regulates hepatic lipogenesis by promoting nuclear entry of ChREBP in response to a high carbohydrate diet

inferred← citeshttps://doi.org/10.1016/j.jcmgh.2017.11.016openalex-snapshot

Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)

inferred← citeshttps://doi.org/10.1016/j.jdermsci.2017.10.004openalex-snapshot

Anacardic acid reduces lipogenesis in human differentiated adipocytes via inhibition of histone acetylation

inferred← citeshttps://doi.org/10.1016/j.jep.2021.114922openalex-snapshot

Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters

inferred← citeshttps://doi.org/10.1016/j.jep.2023.117479openalex-snapshot

Radix Saposhnikoviae enhancing Huangqi Chifeng Decoction improves lipid metabolism in AS mice

inferred← citeshttps://doi.org/10.1016/j.jep.2025.120127openalex-snapshot

Integrating metabolomics and network pharmacology analysis provides new insights into the lipid metabolism disorder of Abrus mollis

inferred← citeshttps://doi.org/10.1016/j.jep.2025.120269openalex-snapshot

Huaganjian decoction ameliorates metabolic dysfunction-associated steatotic liver disease through liver-gut crosstalk

inferred← citeshttps://doi.org/10.1016/j.jff.2020.103780openalex-snapshot

Different source of commercial vegetable oils may regulate metabolic, inflammatory and redox status in healthy rats

inferred← citeshttps://doi.org/10.1016/j.jff.2020.104230openalex-snapshot

Regulatory effects of a Grifola frondosa extract rich in pseudobaptigenin and cyanidin-3-O-xylosylrutinoside on glycolipid metabolism and the gut microbiota in high-fat diet-fed rats

inferred← citeshttps://doi.org/10.1016/j.jff.2022.105189openalex-snapshot

Nasturtium (Tropaeolum majus L.) sub-chronic consumption on insulin resistance and lipid profile in prediabetic subjects. A pilot study

inferred← citeshttps://doi.org/10.1016/j.jff.2023.105594openalex-snapshot

Anti-obesity effects of kimchi with red yeast rice in 3T3-L1 adipocytes and high-fat diet-induced obese mice

inferred← citeshttps://doi.org/10.1016/j.jff.2023.105963openalex-snapshot

Isomalt attenuates hepatic steatosis in rats via modulating gut microbiota and its metabolic function

inferred← citeshttps://doi.org/10.1016/j.jff.2024.106305openalex-snapshot

HPP-1S attenuates oleic acid-induced steatosis in HepG2 cells and nonalcoholic fatty liver disease in a rat model of high-fat diet-induced obesity

inferred← citeshttps://doi.org/10.1016/j.jff.2025.106999openalex-snapshot

Heat-treated culture-dried Lactiplantibacillus Plantarum L-14 suppresses adipogenesis and lipogenesis in 3T3-L1 and HepG2 cells

inferred← citeshttps://doi.org/10.1016/j.jhepr.2022.100479openalex-snapshot

Lipid alterations in chronic liver disease and liver cancer

inferred← citeshttps://doi.org/10.1016/j.jhepr.2024.101303openalex-snapshot

RAP1A suppresses hepatic steatosis by regulating amino acid-mediated mTORC1 activation

inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2018.04.020openalex-snapshot

Comparative assessment of metal-specific adipogenic activity in zinc and vanadium-citrates through associated gene expression

inferred← citeshttps://doi.org/10.1016/j.jlr.2022.100299openalex-snapshot

Analysis of apoB Concentrations Across Early Adulthood and Predictors for Rates of Change Using CARDIA Study Data

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2016.02.006openalex-snapshot

Raspberry seed flour attenuates high-sucrose diet-mediated hepatic stress and adipose tissue inflammation

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2017.04.001openalex-snapshot

Low-dose pollutant mixture triggers metabolic disturbances in female mice leading to common and specific features as compared to a high-fat diet

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2021.108602openalex-snapshot

Tomatidine ameliorates obesity-induced nonalcoholic fatty liver disease in mice

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2021.108882openalex-snapshot

Lipophagy mediated glucose-induced changes of lipid deposition and metabolism via ROS dependent AKT-Beclin1 activation

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2023.109452openalex-snapshot

F6P/G6P-mediated ChREBP activation promotes the insulin resistance-driven hepatic lipid deposition in zebrafish

inferred← citeshttps://doi.org/10.1016/j.jpeds.2021.12.017openalex-snapshot

Hypertriglyceridemia in Youth

inferred← citeshttps://doi.org/10.1016/j.jsps.2018.07.006openalex-snapshot

Ginkgolide C reduced oleic acid-induced lipid accumulation in HepG2 cells

inferred← citeshttps://doi.org/10.1016/j.jtcme.2025.02.010openalex-snapshot

Integration proteomics analysis to identify AMPK as key target pathways of TCM formula for high fat diet induced obesity in mice

inferred← citeshttps://doi.org/10.1016/j.lfs.2022.120812openalex-snapshot

The diabetogenic effects of chronic supplementation of vitamin C or E in rats: Interplay between liver and adipose tissues transcriptional machinery of lipid metabolism

inferred← citeshttps://doi.org/10.1016/j.lfs.2022.121185openalex-snapshot

Shedding light on non-alcoholic fatty liver disease: Pathogenesis, molecular mechanisms, models, and emerging therapeutics

inferred← citeshttps://doi.org/10.1016/j.livres.2018.12.001openalex-snapshot

Hepatic lipid homeostasis by peroxisome proliferator-activated receptor gamma 2

inferred← citeshttps://doi.org/10.1016/j.livres.2020.02.002openalex-snapshot

Lipid and energy metabolism in Wilson disease

inferred← citeshttps://doi.org/10.1016/j.livres.2020.02.004openalex-snapshot

Nutrient mTORC1 signaling contributes to hepatic lipid metabolism in the pathogenesis of non-alcoholic fatty liver disease

inferred← citeshttps://doi.org/10.1016/j.mam.2018.09.002openalex-snapshot

Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues

inferred← citeshttps://doi.org/10.1016/j.mce.2017.10.010openalex-snapshot

LAMP3 regulates hepatic lipid metabolism through activating PI3K/Akt pathway

inferred← citeshttps://doi.org/10.1016/j.mce.2018.10.014openalex-snapshot

Role of HSD17B13 in the liver physiology and pathophysiology

inferred← citeshttps://doi.org/10.1016/j.mce.2019.03.006openalex-snapshot

Effects of in utero androgen excess and metformin treatment on hepatic functions

inferred← citeshttps://doi.org/10.1016/j.mce.2021.111265openalex-snapshot

Distinctive functioning of STARD1 in the fetal Leydig cells compared to adult Leydig and adrenal cells. Impact of Hedgehog signaling via the primary cilium

inferred← citeshttps://doi.org/10.1016/j.mce.2025.112611openalex-snapshot

Timing of glucose intake drives distinct hepatic outcomes: Divergent glucose and lipid metabolism

inferred← citeshttps://doi.org/10.1016/j.mce.2025.112676openalex-snapshot

Interrelationship between alcohol consumption, overnutrition, and pharmacotherapy for liver steatosis: Considerations and proposals

inferred← citeshttps://doi.org/10.1016/j.metabol.2019.01.018openalex-snapshot

LncRNA MEG3 functions as a ceRNA in regulating hepatic lipogenesis by competitively binding to miR-21 with LRP6

inferred← citeshttps://doi.org/10.1016/j.metabol.2019.03.010openalex-snapshot

Chitinase-3-like-1 deficiency attenuates ethanol-induced liver injury by inhibition of sterol regulatory element binding protein 1-dependent triglyceride synthesis

inferred← citeshttps://doi.org/10.1016/j.metabol.2019.153954openalex-snapshot

The metabolic regulator small heterodimer partner contributes to the glucose and lipid homeostasis abnormalities induced by hepatitis C virus infection

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