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GPX4 Transcriptionally Promotes Hepatocellular Carcinoma Metastasis via GRHL3/PI3K/AKT Axis

https://doi.org/10.2139/ssrn.4350587
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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s10549-021-06301-9openalex-extracted
ZEB1 directly inhibits GPX4 transcription contributing to ROS accumulation in breast cancer cells
inferredcites →https://doi.org/10.1016/j.biopha.2020.110092openalex-extracted
Actinidia chinensis Planch prevents proliferation and migration of gastric cancer associated with apoptosis, ferroptosis activation and mesenchymal phenotype suppression
inferredcites →https://doi.org/10.1016/j.canlet.2021.09.014openalex-extracted
KLF2 inhibits cancer cell migration and invasion by regulating ferroptosis through GPX4 in clear cell renal cell carcinoma
inferredcites →https://doi.org/10.1016/j.ccell.2017.11.004openalex-extracted
Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis
inferredcites →https://doi.org/10.1016/j.ccell.2019.12.007openalex-extracted
Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
inferredcites →https://doi.org/10.1016/j.ebiom.2019.08.037openalex-extracted
Variants in oxidative stress-related genes affect the chemosensitivity through Nrf2-mediated signaling pathway in biliary tract cancer
inferredcites →https://doi.org/10.1016/j.tcb.2015.10.014openalex-extracted
Ferroptosis: Death by Lipid Peroxidation
inferredcites →https://doi.org/10.1016/j.tcb.2018.12.001openalex-extracted
EMT Transition States during Tumor Progression and Metastasis
inferredcites →https://doi.org/10.1016/s0140-6736(18)30010-2openalex-extracted
Hepatocellular carcinoma
inferredcites →https://doi.org/10.1038/nrm4074openalex-extracted
Transcriptional regulation of hepatic lipogenesis
inferredcites →https://doi.org/10.1038/onc.2017.178openalex-extracted
Roles of Grainyhead-like transcription factors in cancer
inferredcites →https://doi.org/10.1038/s41418-021-00821-zopenalex-extracted
SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis
inferredcites →https://doi.org/10.1038/s41422-020-00441-1openalex-extracted
Ferroptosis: molecular mechanisms and health implications
inferredcites →https://doi.org/10.1038/s41467-020-15646-6openalex-extracted
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn’s disease
inferredcites →https://doi.org/10.1038/s41467-020-20674-3openalex-extracted
Epidermal progenitors suppress GRHL3-mediated differentiation through intronic polyadenylation promoted by CPSF-HNRNPA3 collaboration
inferredcites →https://doi.org/10.1038/s41572-020-00240-3openalex-extracted
Hepatocellular carcinoma
inferredcites →https://doi.org/10.1038/s41580-020-00324-8openalex-extracted
Ferroptosis: mechanisms, biology and role in disease
inferredcites →https://doi.org/10.1053/j.gastro.2016.11.048openalex-extracted
Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis
inferredcites →https://doi.org/10.1056/nejmra1713263openalex-extracted
Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1093/jnci/djab131openalex-extracted
Annual Report to the Nation on the Status of Cancer, Part 1: National Cancer Statistics
inferredcites →https://doi.org/10.1155/2021/6004821openalex-extracted
GRHL3 Promotes Tumor Growth and Metastasis via the MEK Pathway in Colorectal Cancer
inferredcites →https://doi.org/10.1155/2022/3920664openalex-extracted
Ferritinophagy‐Mediated Ferroptosis and Activation of Keap1/Nrf2/HO‐1 Pathway Were Conducive to EMT Inhibition of Gastric Cancer Cells in Action of 2,2 ′‐Di‐pyridineketone Hydrazone Dithiocarbamate Butyric Acid Ester
inferredcites →https://doi.org/10.1186/s12943-018-0915-9openalex-extracted
BRD4 and Cancer: going beyond transcriptional regulation
inferredcites →https://doi.org/10.1186/s12943-020-01157-xopenalex-extracted
The epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression
inferredcites →https://doi.org/10.1186/s13045-020-01016-8openalex-extracted
Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple negative breast cancer cells
inferredcites →https://doi.org/10.2147/cmar.s252962openalex-extracted
Expression Analysis of GRHL3 and PHLDA3 in Head and Neck Squamous Cell Carcinoma
inferredcites →https://doi.org/10.3389/fcell.2021.822315openalex-extracted
Single-Cell RNA-Seq Reveals the Promoting Role of Ferroptosis Tendency During Lung Adenocarcinoma EMT Progression
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