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CX3CR1 Deficiency Does Not Influence Trafficking of Adipose Tissue Macrophages in Mice With Diet‐Induced Obesity

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s00125-009-1378-8openalex-snapshot
Apolipoprotein E deficiency abrogates insulin resistance in a mouse model of type 2 diabetes mellitus
inferredcites →https://doi.org/10.1016/j.cellimm.2009.04.003openalex-snapshot
PPAR γ is highly expressed in F4/80hi adipose tissue macrophages and dampens adipose-tissue inflammation
inferredcites →https://doi.org/10.1016/j.cmet.2008.08.015openalex-snapshot
Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals
inferredcites →https://doi.org/10.1016/j.vph.2009.12.004openalex-snapshot
The role of chemokines in recruitment of immune cells to the artery wall and adipose tissue
inferredcites →https://doi.org/10.1016/s0092-8674(00)80438-9openalex-snapshot
Identification and Molecular Characterization of Fractalkine Receptor CX3CR1, which Mediates Both Leukocyte Migration and Adhesion
inferredcites →https://doi.org/10.1016/s1074-7613(03)00174-2openalex-snapshot
Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties
inferredcites →https://doi.org/10.1038/icb.2008.19openalex-snapshot
Blood monocytes: distinct subsets, how they relate to dendritic cells, and their possible roles in the regulation of T‐cell responses
inferredcites →https://doi.org/10.1038/nature05485openalex-snapshot
Inflammation and metabolic disorders
inferredcites →https://doi.org/10.1038/nature08636openalex-snapshot
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
inferredcites →https://doi.org/10.1038/nm.1994openalex-snapshot
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
inferredcites →https://doi.org/10.1038/nm.2001openalex-snapshot
Normalization of obesity-associated insulin resistance through immunotherapy
inferredcites →https://doi.org/10.1038/nm.2353openalex-snapshot
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
inferredcites →https://doi.org/10.1038/sj.ijo.0803632openalex-snapshot
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
inferredcites →https://doi.org/10.1073/pnas.0408096101openalex-snapshot
Major reduction of atherosclerosis in fractalkine (CX3CL1)-deficient mice is at the brachiocephalic artery, not the aortic root
inferredcites →https://doi.org/10.1074/jbc.m804220200openalex-snapshot
Role of CC Chemokine Receptor 2 in Bone Marrow Cells in the Recruitment of Macrophages into Obese Adipose Tissue
inferredcites →https://doi.org/10.1084/jem.20091333openalex-snapshot
MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity
inferredcites →https://doi.org/10.1084/jem.20091925openalex-snapshot
Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions
inferredcites →https://doi.org/10.1146/annurev-physiol-021909-135846openalex-snapshot
Macrophages, Inflammation, and Insulin Resistance
inferredcites →https://doi.org/10.1152/ajpendo.00050.2010openalex-snapshot
Absence of macrophage inflammatory protein-1α does not impact macrophage accumulation in adipose tissue of diet-induced obese mice
inferredcites →https://doi.org/10.1161/01.hyp.0000171477.63859.b2openalex-snapshot
Adipose Tissue Metabolism and CD11b Expression on Monocytes in Obese Hypertensives
inferredcites →https://doi.org/10.1161/atvbaha.107.158675openalex-snapshot
CX 3 CR1 Deficiency Impairs Dendritic Cell Accumulation in Arterial Intima and Reduces Atherosclerotic Burden
inferredcites →https://doi.org/10.1161/atvbaha.109.195826openalex-snapshot
Lack of Association Between Adiponectin Levels and Atherosclerosis in Mice
inferredcites →https://doi.org/10.1161/atvbaha.109.198044openalex-snapshot
CD11c Expression in Adipose Tissue and Blood and Its Role in Diet-Induced Obesity
inferredcites →https://doi.org/10.1161/circulationaha.107.743872openalex-snapshot
Fractalkine Deficiency Markedly Reduces Macrophage Accumulation and Atherosclerotic Lesion Formation in CCR2 −/− Mice
inferredcites →https://doi.org/10.1161/circulationaha.107.745091openalex-snapshot
Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C hi and Ly6C lo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice
inferredcites →https://doi.org/10.1172/jci15555openalex-snapshot
Decreased atherosclerosis in CX3CR1–/– mice reveals a role for fractalkine in atherogenesis
inferredcites →https://doi.org/10.1172/jci19246openalex-snapshot
Obesity is associated with macrophage accumulation in adipose tissue
inferredcites →https://doi.org/10.1172/jci19451openalex-snapshot
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
inferredcites →https://doi.org/10.1172/jci24335openalex-snapshot
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
inferredcites →https://doi.org/10.1172/jci24335c1openalex-snapshot
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
inferredcites →https://doi.org/10.1172/jci26498openalex-snapshot
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
inferredcites →https://doi.org/10.1172/jci28549openalex-snapshot
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques
inferredcites →https://doi.org/10.1172/jci29069openalex-snapshot
Inflammation and insulin resistance
inferredcites →https://doi.org/10.1172/jci29881openalex-snapshot
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
inferredcites →https://doi.org/10.1172/jci30992openalex-snapshot
Macrophage heterogeneity and tissue lipids
inferredcites →https://doi.org/10.1172/jci33328openalex-snapshot
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue
inferredcites →https://doi.org/10.1172/jci42845openalex-snapshot
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
inferredcites →https://doi.org/10.1182/blood-2008-07-170787openalex-snapshot
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival
inferredcites →https://doi.org/10.2337/db07-0767openalex-snapshot
Adipocyte Death, Adipose Tissue Remodeling, and Obesity Complications
inferredcites →https://doi.org/10.2337/db07-1061openalex-snapshot
Monocyte Chemoattractant Protein-1 Deficiency Fails to Restrain Macrophage Infiltration Into Adipose Tissue
inferredcites →https://doi.org/10.2337/db08-0872openalex-snapshot
Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes
inferredcites →https://doi.org/10.2337/db10-0956openalex-snapshot
Fractalkine Is a Novel Human Adipochemokine Associated With Type 2 Diabetes
inferredcites →https://doi.org/10.2337/db11-0314openalex-snapshot
Aberrant Accumulation of Undifferentiated Myeloid Cells in the Adipose Tissue of CCR2-Deficient Mice Delays Improvements in Insulin Sensitivity

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4775199openalex-extracted
Visualizing the Spatial Organization of Monocytes, Connective and Tissue Specific Macrophages in situ
inferred← citeshttps://doi.org/10.1002/jlb.3hi1017-422ropenalex-snapshot
Frontline Science: Rapid adipose tissue expansion triggers unique proliferation and lipid accumulation profiles in adipose tissue macrophages
inferred← citeshttps://doi.org/10.1002/oby.20642openalex-snapshot
CXCR3 modulates obesity‐induced visceral adipose inflammation and systemic insulin resistance
inferred← citeshttps://doi.org/10.1002/oby.21900openalex-snapshot
Synergistic Modulation of Inflammatory but not Metabolic Effects of High‐Fat Feeding by CCR2 and CX3CR1
inferred← citeshttps://doi.org/10.1002/oby.22674openalex-snapshot
Adipose Tissue Macrophage Phenotypes and Characteristics: The Key to Insulin Resistance in Obesity and Metabolic Disorders
inferred← citeshttps://doi.org/10.1007/978-1-4614-6819-6_4openalex-snapshot
Adipose Tissue Macrophages in Obesity, Inflammation, and Cancer
inferred← citeshttps://doi.org/10.1007/s00125-016-4181-3openalex-snapshot
Glia: silent partners in energy homeostasis and obesity pathogenesis
inferred← citeshttps://doi.org/10.1007/s00441-015-2253-1openalex-snapshot
Adipose tissue macrophages in non-rodent mammals: a comparative study
inferred← citeshttps://doi.org/10.1007/s12272-013-0023-8openalex-snapshot
Adipose tissue macrophages in the development of obesity-induced inflammation, insulin resistance and type 2 Diabetes
inferred← citeshttps://doi.org/10.1016/b978-0-12-411619-1.00016-1openalex-snapshot
Flow Cytometry Analyses of Adipose Tissue Macrophages
inferred← citeshttps://doi.org/10.1016/j.asmr.2023.03.013openalex-snapshot
Arthroscopic Implantation of Adipose‐Derived Stromal Vascular Fraction Improves Cartilage Regeneration and Pain Relief in Patients With Knee Osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.asmr.2023.04.002openalex-snapshot
Adipose‐Derived Stromal Vascular Fractions Are Comparable With Allogenic Human Umbilical Cord Blood–Derived Mesenchymal Stem Cells as a Supplementary Strategy of High Tibial Osteotomy for Varus Knee Osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2013.12.005openalex-snapshot
Secretion of adipocytokines by perivascular adipose tissue near stenotic and non-stenotic coronary artery segments in patients undergoing CABG
inferred← citeshttps://doi.org/10.1016/j.bbadis.2013.05.017openalex-snapshot
Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance
inferred← citeshttps://doi.org/10.1016/j.bbalip.2016.07.002openalex-snapshot
Brown adipose tissue in obesity: Fractalkine-receptor dependent immune cell recruitment affects metabolic-related gene expression
inferred← citeshttps://doi.org/10.1016/j.bbi.2014.01.010openalex-snapshot
The fractalkine/Cx3CR1 system is implicated in the development of metabolic visceral adipose tissue inflammation in obesity
inferred← citeshttps://doi.org/10.1016/j.cell.2013.03.001openalex-snapshot
The Fractalkine/CX3CR1 System Regulates β Cell Function and Insulin Secretion
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114847openalex-snapshot
Visualizing the spatial organization of monocytes, interstitial macrophages, and tissue-specific macrophages in situ
inferred← citeshttps://doi.org/10.1016/j.metabol.2022.155272openalex-snapshot
CX3CL1/CX3CR1 interaction protects against lipotoxicity-induced nonalcoholic steatohepatitis by regulating macrophage migration and M1/M2 status
inferred← citeshttps://doi.org/10.1016/j.molmet.2014.06.005openalex-snapshot
Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells
inferred← citeshttps://doi.org/10.1016/j.molmet.2015.07.005openalex-snapshot
Activation of NF-κB drives the enhanced survival of adipose tissue macrophages in an obesogenic environment
inferred← citeshttps://doi.org/10.1016/j.nutres.2013.07.017openalex-snapshot
High-fat diet action on adiposity, inflammation, and insulin sensitivity depends on the control low-fat diet
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2014.09.007openalex-snapshot
An atlas of G-protein coupled receptor expression and function in human subcutaneous adipose tissue
inferred← citeshttps://doi.org/10.1038/ijo.2017.179openalex-snapshot
Modulation of Gr1low monocyte subset impacts insulin sensitivity and weight gain upon high-fat diet in female mice
inferred← citeshttps://doi.org/10.1038/ncomms14556openalex-snapshot
Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice
inferred← citeshttps://doi.org/10.1038/s41598-019-52583-xopenalex-snapshot
Programming effects of maternal and gestational obesity on offspring metabolism and metabolic inflammation
inferred← citeshttps://doi.org/10.1038/srep42665openalex-snapshot
Circulating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue
inferred← citeshttps://doi.org/10.1042/bsr20220200openalex-snapshot
Adipose tissue macrophages and their role in obesity-associated insulin resistance: an overview of the complex dynamics at play
inferred← citeshttps://doi.org/10.1053/j.ajkd.2015.01.021openalex-snapshot
Serum Fractalkine (CX3CL1) and Cardiovascular Outcomes and Diabetes: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study
inferred← citeshttps://doi.org/10.1074/jbc.m114.634568openalex-snapshot
Differences in Hematopoietic Stem Cells Contribute to Sexually Dimorphic Inflammatory Responses to High Fat Diet-induced Obesity
inferred← citeshttps://doi.org/10.1074/jbc.ra117.001526openalex-snapshot
TLR4, TRIF, and MyD88 are essential for myelopoiesis and CD11c+ adipose tissue macrophage production in obese mice
inferred← citeshttps://doi.org/10.1080/21623945.2015.1027848openalex-snapshot
Obesity-induced remodeling of the adipose tissue elastin network is independent of the metalloelastase MMP-12
inferred← citeshttps://doi.org/10.1084/jem.20131314openalex-snapshot
MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases
inferred← citeshttps://doi.org/10.1089/ten.teb.2017.0061openalex-snapshot
The Adipose Stromal Vascular Fraction as a Complex Cellular Source for Tissue Engineering Applications
inferred← citeshttps://doi.org/10.1097/scs.0000000000010386openalex-snapshot
M2 Macrophage Polarization and Tissue Remodeling in Autologous Fat Grafting for Diabetic Skin Defects
inferred← citeshttps://doi.org/10.1111/dme.12451openalex-snapshot
Serum levels of fractalkine are associated with markers of insulin resistance in gestational diabetes
inferred← citeshttps://doi.org/10.1111/imcb.12360openalex-snapshot
Adipose‐resident myeloid‐derived suppressor cells modulate immune cell homeostasis in healthy mice
inferred← citeshttps://doi.org/10.1111/obr.12242openalex-snapshot
Macrophage recruitment in obese adipose tissue
inferred← citeshttps://doi.org/10.1124/pr.113.008268openalex-snapshot
Transient Receptor Potential Channels as Drug Targets: From the Science of Basic Research to the Art of Medicine
inferred← citeshttps://doi.org/10.1148/radiol.12120418openalex-snapshot
Science to Practice: Why Follow the Track of Macrophages in Obesity?
inferred← citeshttps://doi.org/10.1152/ajpendo.00177.2013openalex-snapshot
Loss of CCR5 results in glucose intolerance in diet-induced obese mice
inferred← citeshttps://doi.org/10.1161/atvbaha.119.312425openalex-snapshot
Significance of Cellular Cross-Talk in Stromal Vascular Fraction of Adipose Tissue in Neovascularization
inferred← citeshttps://doi.org/10.1177/09636897211067454openalex-snapshot
Comparison of Clinical and Imaging Outcomes of Different Doses of Adipose-Derived Stromal Vascular Fraction Cell Treatment for Knee Osteoarthritis
inferred← citeshttps://doi.org/10.1182/blood-2014-04-568691openalex-snapshot
Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in vivo
inferred← citeshttps://doi.org/10.1186/s13018-020-01664-zopenalex-snapshot
Intra-articular infiltration of adipose-derived stromal vascular fraction cells slows the clinical progression of moderate-severe knee osteoarthritis: hypothesis on the regulatory role of intra-articular adipose tissue
inferred← citeshttps://doi.org/10.1186/s13287-022-02788-1openalex-snapshot
Mid-term prognosis of the stromal vascular fraction for knee osteoarthritis: a minimum 5-year follow-up study
inferred← citeshttps://doi.org/10.1189/jlb.3a0115-009ropenalex-snapshot
CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity
inferred← citeshttps://doi.org/10.1210/en.2013-1587openalex-snapshot
Thrombospondin 1 Mediates High-Fat Diet-Induced Muscle Fibrosis and Insulin Resistance in Male Mice
inferred← citeshttps://doi.org/10.1210/en.2013-2027openalex-snapshot
What Have We Really Learned About Macrophage Recruitment to Adipose Tissue?
inferred← citeshttps://doi.org/10.1210/en.2018-00797openalex-snapshot
Sex Differences in Inflammatory Responses to Adipose Tissue Lipolysis in Diet-Induced Obesity
inferred← citeshttps://doi.org/10.1210/endocr/bqab064openalex-snapshot
CX3CL1-CX3CR1 Signaling Deficiency Exacerbates Obesity-induced Inflammation and Insulin Resistance in Male Mice
inferred← citeshttps://doi.org/10.1371/journal.pone.0057929openalex-snapshot
Neuropeptide Y Is Produced by Adipose Tissue Macrophages and Regulates Obesity-Induced Inflammation
inferred← citeshttps://doi.org/10.1371/journal.pone.0138317openalex-snapshot
Metabolic Effects of CX3CR1 Deficiency in Diet-Induced Obese Mice
inferred← citeshttps://doi.org/10.1515/jomb-2017-0070openalex-snapshot
Effects of Glucose Ingestion on Serum Fractalkine Levels in Healthy Subjects and Newly Diagnosed Type 2 Diabetic Patients
inferred← citeshttps://doi.org/10.1615/critrevimmunol.2013006833openalex-snapshot
Changes in Adipose Tissue Macrophages and T Cells During Aging
inferred← citeshttps://doi.org/10.17615/qnnk-hw78openalex-snapshot
The Effect of a High Fat Diet on the Brain Following HSV-1 Infection
inferred← citeshttps://doi.org/10.2337/db12-1404openalex-snapshot
Adipose Tissue Macrophages Function As Antigen-Presenting Cells and Regulate Adipose Tissue CD4+ T Cells in Mice
inferred← citeshttps://doi.org/10.3389/fimmu.2018.00169openalex-snapshot
Parallels in Immunometabolic Adipose Tissue Dysfunction with Ageing and Obesity
inferred← citeshttps://doi.org/10.3389/fimmu.2018.01867openalex-snapshot
Identifying a Novel Role for Fractalkine (CX3CL1) in Memory CD8+ T Cell Accumulation in the Omentum of Obesity-Associated Cancer Patients
inferred← citeshttps://doi.org/10.3389/fimmu.2019.01173openalex-snapshot
Adipose Tissue-Resident Immune Cells in Obesity and Type 2 Diabetes
inferred← citeshttps://doi.org/10.3390/ijms19041095openalex-snapshot
Global Transcriptome Analysis of Brown Adipose Tissue of Diet-Induced Obese Mice
inferred← citeshttps://doi.org/10.3390/ijms22158008openalex-snapshot
Effect of Microbiome on Non-Alcoholic Fatty Liver Disease and the Role of Probiotics, Prebiotics, and Biogenics
inferred← citeshttps://doi.org/10.3390/ijms26146597openalex-snapshot
Vital Role of Visceral Adipose Tissue in Maintaining Cognitive Functions
inferred← citeshttps://doi.org/10.4161/isl.27861openalex-snapshot
Fractalkine signaling in regulation of insulin secretion
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