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Apical junctional complexes and cell polarity

https://doi.org/10.1038/sj.ki.5002579

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/dvdy.20595openalex-snapshot

DPATJ plays a role in retinal morphogenesis and protects against light‐dependent degeneration of photoreceptor cells in the Drosophila eye

inferredcites →https://doi.org/10.1002/yea.1409openalex-snapshot

Role of Rho GTPases and Rho‐GEFs in the regulation of cell shape and integrity in fission yeast

inferredcites →https://doi.org/10.1006/dbio.1993.1243openalex-snapshot

crumbs and stardust Act in a Genetic Pathway That Controls the Organization of Epithelia in Drosophila melanogaster

inferredcites →https://doi.org/10.1006/dbio.1996.0157openalex-snapshot

Crumbs, a Component of the Apical Membrane, Is Required for Zonula Adherens Formation in Primary Epithelia ofDrosophila

inferredcites →https://doi.org/10.1006/jsbi.2000.4244openalex-snapshot

Ultrastructure of the Zonula Adherens Revealed by Rapid-Freeze Deep-Etching

inferredcites →https://doi.org/10.1007/bf01870332openalex-snapshot

Morphological factors influencing transepithelial permeability: A model for the resistance of theZonula Occludens

inferredcites →https://doi.org/10.1016/0092-8674(95)90053-5openalex-snapshot

Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of drosophila

inferredcites →https://doi.org/10.1016/j.ceb.2006.02.005openalex-snapshot

Regulation of Par6 by extracellular signals

inferredcites →https://doi.org/10.1016/j.cell.2005.03.014openalex-snapshot

The Apical Determinants aPKC and dPatj Regulate Frizzled-Dependent Planar Cell Polarity in the Drosophila Eye

inferredcites →https://doi.org/10.1016/j.cell.2006.02.045openalex-snapshot

A Rich1/Amot Complex Regulates the Cdc42 GTPase and Apical-Polarity Proteins in Epithelial Cells

inferredcites →https://doi.org/10.1016/j.cell.2006.04.011openalex-snapshot

Closing the GAP between Polarity and Vesicle Transport

inferredcites →https://doi.org/10.1016/j.cell.2006.11.051openalex-snapshot

PTEN-Mediated Apical Segregation of Phosphoinositides Controls Epithelial Morphogenesis through Cdc42

inferredcites →https://doi.org/10.1016/j.cub.2003.11.020openalex-snapshot

Phosphorylation-Dependent Binding of 14-3-3 to the Polarity Protein Par3 Regulates Cell Polarity in Mammalian Epithelia

inferredcites →https://doi.org/10.1016/j.cub.2004.04.006openalex-snapshot

Zebrafish Mosaic Eyes Is a Novel FERM Protein Required for Retinal Lamination and Retinal Pigmented Epithelial Tight Junction Formation

inferredcites →https://doi.org/10.1016/j.cub.2004.04.007openalex-snapshot

Atypical PKC Phosphorylates PAR-1 Kinases to Regulate Localization and Activity

inferredcites →https://doi.org/10.1016/j.cub.2004.08.021openalex-snapshot

aPKC Acts Upstream of PAR-1b in Both the Establishment and Maintenance of Mammalian Epithelial Polarity

inferredcites →https://doi.org/10.1016/j.cub.2004.08.025openalex-snapshot

Polarity Proteins Control Ciliogenesis via Kinesin Motor Interactions

inferredcites →https://doi.org/10.1016/j.cub.2005.11.068openalex-snapshot

Regulated and Polarized PtdIns(3,4,5)P3 Accumulation Is Essential for Apical Membrane Morphogenesis in Photoreceptor Epithelial Cells

inferredcites →https://doi.org/10.1016/j.devcel.2005.03.003openalex-snapshot

Binding of GEF-H1 to the Tight Junction-Associated Adaptor Cingulin Results in Inhibition of Rho Signaling and G1/S Phase Transition

inferredcites →https://doi.org/10.1016/j.devcel.2006.06.001openalex-snapshot

The FERM Protein Yurt Is a Negative Regulatory Component of the Crumbs Complex that Controls Epithelial Polarity and Apical Membrane Size

inferredcites →https://doi.org/10.1016/j.ejcb.2006.03.003openalex-snapshot

Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila Crumbs for the PDZ domains of Stardust and DmPar-6

inferredcites →https://doi.org/10.1016/s0021-9258(18)54107-7openalex-snapshot

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

inferredcites →https://doi.org/10.1016/s0076-6879(06)06029-0openalex-snapshot

Rho GTPase Activation by Cell–Cell Adhesion

inferredcites →https://doi.org/10.1016/s0092-8674(01)00471-8openalex-snapshot

Integrin-Mediated Activation of Cdc42 Controls Cell Polarity in Migrating Astrocytes through PKCζ

inferredcites →https://doi.org/10.1016/s0092-8674(02)01249-7openalex-snapshot

Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity

inferredcites →https://doi.org/10.1016/s0092-8674(03)00938-3openalex-snapshot

Drosophila PAR-1 and 14-3-3 Inhibit Bazooka/PAR-3 to Establish Complementary Cortical Domains in Polarized Cells

inferredcites →https://doi.org/10.1016/s0092-8674(04)00114-xopenalex-snapshot

Complete Polarization of Single Intestinal Epithelial Cells upon Activation of LKB1 by STRAD

inferredcites →https://doi.org/10.1016/s0092-8674(88)80024-2openalex-snapshot

Identification of genes required for cytoplasmic localization in early C. elegans embryos

inferredcites →https://doi.org/10.1016/s0378-1119(02)00681-9openalex-snapshot

Multiple splice variants of Par3 and of a novel related gene, Par3L , produce proteins with different binding properties

inferredcites →https://doi.org/10.1016/s0378111902010843openalex-snapshot

Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1)

inferredcites →https://doi.org/10.1016/s0955-0674(02)00373-3openalex-snapshot

Cell–cell adhesion and signalling

inferredcites →https://doi.org/10.1016/s0955-0674(03)00097-8openalex-snapshot

Roles of Rho-family GTPases in cell polarisation and directional migration

inferredcites →https://doi.org/10.1016/s0960-9822(00)00535-2openalex-snapshot

A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCζ signaling and cell transformation

inferredcites →https://doi.org/10.1016/s0960-9822(01)00663-7openalex-snapshot

Assembly of Epithelial Tight Junctions Is Negatively Regulated by Par6

inferredcites →https://doi.org/10.1016/s0960-9822(03)00244-6openalex-snapshot

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

inferredcites →https://doi.org/10.1016/s0960-9822(03)00508-6openalex-snapshot

A Conserved Oligomerization Domain in Drosophila Bazooka/PAR-3 Is Important for Apical Localization and Epithelial Polarity

inferredcites →https://doi.org/10.1016/s0960-9822(99)00277-8openalex-snapshot

A conserved motif in Crumbs is required for E-cadherin localisation and zonula adherens formation in Drosophila

inferredcites →https://doi.org/10.1016/s1534-5807(02)00259-9openalex-snapshot

Actin Cable Dynamics and Rho/Rock Orchestrate a Polarized Cytoskeletal Architecture in the Early Steps of Assembling a Stratified Epithelium

inferredcites →https://doi.org/10.1038/13848openalex-snapshot

Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12)

inferredcites →https://doi.org/10.1038/294718a0openalex-snapshot

Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane?

inferredcites →https://doi.org/10.1038/35019573openalex-snapshot

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

inferredcites →https://doi.org/10.1038/35019582openalex-snapshot

A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

inferredcites →https://doi.org/10.1038/35019592openalex-snapshot

Stimulation of erythropoiesis by inhibiting a new hematopoietic death receptor in transgenic zebrafish

inferredcites →https://doi.org/10.1038/35046087openalex-snapshot

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

inferredcites →https://doi.org/10.1038/35046094openalex-snapshot

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

inferredcites →https://doi.org/10.1038/35050550openalex-snapshot

DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila

inferredcites →https://doi.org/10.1038/414634aopenalex-snapshot

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts

inferredcites →https://doi.org/10.1038/414638aopenalex-snapshot

Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity

inferredcites →https://doi.org/10.1038/nature01486openalex-snapshot

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

inferredcites →https://doi.org/10.1038/nature01602openalex-snapshot

Adaptation of core mechanisms to generate cell polarity

inferredcites →https://doi.org/10.1038/ncb1226openalex-snapshot

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1

inferredcites →https://doi.org/10.1038/ncb1227openalex-snapshot

PAR-6–PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1

inferredcites →https://doi.org/10.1038/ncb1324openalex-snapshot

Endocytic control of epithelial polarity and proliferation in Drosophila

inferredcites →https://doi.org/10.1038/ncb1461openalex-snapshot

Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells

inferredcites →https://doi.org/10.1038/ncb796openalex-snapshot

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

inferredcites →https://doi.org/10.1038/ncb923openalex-snapshot

Direct interaction of two polarity complexes implicated in epithelial tight junction assembly

inferredcites →https://doi.org/10.1038/ncb948openalex-snapshot

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl

inferredcites →https://doi.org/10.1038/ng883openalex-snapshot

nagie oko, encoding a MAGUK-family protein, is essential for cellular patterning of the retina

inferredcites →https://doi.org/10.1038/nrc822openalex-snapshot

Epithelial–mesenchymal transitions in tumour progression

inferredcites →https://doi.org/10.1038/nrm1332openalex-snapshot

Parsing the Polarity Code

inferredcites →https://doi.org/10.1038/nsmb839openalex-snapshot

Internal recognition through PDZ domain plasticity in the Par-6–Pals1 complex

inferredcites →https://doi.org/10.1038/sj.onc.1210508openalex-snapshot

The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity

inferredcites →https://doi.org/10.1073/pnas.2135347100openalex-snapshot

Distinct roles of Bazooka and Stardust in the specification of Drosophila photoreceptor membrane architecture

inferredcites →https://doi.org/10.1074/jbc.275.15.11425openalex-snapshot

Molecular Cloning and Characterization of Pals, Proteins Associated with mLin-7

inferredcites →https://doi.org/10.1074/jbc.c200707200openalex-snapshot

Direct Binding of Cell Polarity Protein PAR-3 to Cell-Cell Adhesion Molecule Nectin at Neuroepithelial Cells of Developing Mouse

inferredcites →https://doi.org/10.1074/jbc.m201177200openalex-snapshot

The Carboxyl Terminus of Zona Occludens-3 Binds and Recruits a Mammalian Homologue of Discs Lost to Tight Junctions

inferredcites →https://doi.org/10.1074/jbc.m202196200openalex-snapshot

hINADl/PATJ, a Homolog of Discs Lost, Interacts with Crumbs and Localizes to Tight Junctions in Human Epithelial Cells

inferredcites →https://doi.org/10.1074/jbc.m303593200openalex-snapshot

Self-association of PAR-3-mediated by the Conserved N-terminal Domain Contributes to the Development of Epithelial Tight Junctions

inferredcites →https://doi.org/10.1074/jbc.m306330200openalex-snapshot

Molecular Recognition in Dimerization between PB1 Domains

inferredcites →https://doi.org/10.1074/jbc.m401192200openalex-snapshot

The Rac Exchange Factor Tiam1 Is Required for the Establishment and Maintenance of Cadherin-based Adhesions

inferredcites →https://doi.org/10.1074/jbc.m401930200openalex-snapshot

Tight Junction Protein Par6 Interacts with an Evolutionarily Conserved Region in the Amino Terminus of PALS1/Stardust

inferredcites →https://doi.org/10.1074/jbc.m403723200openalex-snapshot

Isoforms of the Polarity Protein Par6 Have Distinct Functions

inferredcites →https://doi.org/10.1083/jcb.150.6.1361openalex-snapshot

Drosophila Atypical Protein Kinase C Associates with Bazooka and Controls Polarity of Epithelia and Neuroblasts

inferredcites →https://doi.org/10.1083/jcb.152.6.1183openalex-snapshot

Atypical Protein Kinase C Is Involved in the Evolutionarily Conserved Par Protein Complex and Plays a Critical Role in Establishing Epithelia-Specific Junctional Structures

inferredcites →https://doi.org/10.1083/jcb.200103047openalex-snapshot

Junctional adhesion molecule (JAM) binds to PAR-3

inferredcites →https://doi.org/10.1083/jcb.200109010openalex-snapshot

The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost

inferredcites →https://doi.org/10.1083/jcb.200306079openalex-snapshot

Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia

inferredcites →https://doi.org/10.1083/jcb.200311031openalex-snapshot

DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila

inferredcites →https://doi.org/10.1083/jcb.200406024openalex-snapshot

Adherens junction-dependent and -independent steps in the establishment of epithelial cell polarity in Drosophila

inferredcites →https://doi.org/10.1083/jcb.200408064openalex-snapshot

PATJ regulates tight junction formation and polarity in mammalian epithelial cells

inferredcites →https://doi.org/10.1083/jcb.200502129openalex-snapshot

The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex

inferredcites →https://doi.org/10.1083/jcb.200505127openalex-snapshot

The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila

inferredcites →https://doi.org/10.1083/jcb.200510061openalex-snapshot

Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly

inferredcites →https://doi.org/10.1083/jcb.200603156openalex-snapshot

Phosphoinositide signaling plays a key role in cytokinesis

inferredcites →https://doi.org/10.1083/jcb.200605012openalex-snapshot

Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells

inferredcites →https://doi.org/10.1083/jcb.200606116openalex-snapshot

Involvement of zebrafish Na+,K+ ATPase in myocardial cell junction maintenance

inferredcites →https://doi.org/10.1086/321263openalex-snapshot

Leber Congenital Amaurosis and Retinitis Pigmentosa with Coats-like Exudative Vasculopathy Are Associated with Mutations in the Crumbs Homologue 1 (CRB1) Gene

inferredcites →https://doi.org/10.1091/mbc.e03-04-0235openalex-snapshot

CRB3 Binds Directly to Par6 and Regulates the Morphogenesis of the Tight Junctions in Mammalian Epithelial Cells

inferredcites →https://doi.org/10.1091/mbc.e03-08-0620openalex-snapshot

Loss of PALS1 Expression Leads to Tight Junction and Polarity Defects

inferredcites →https://doi.org/10.1091/mbc.e04-09-0827openalex-snapshot

Fractionation of the Epithelial Apical Junctional Complex: Reassessment of Protein Distributions in Different Substructures

inferredcites →https://doi.org/10.1091/mbc.e06-07-0651openalex-snapshot

PALS1 Regulates E-Cadherin Trafficking in Mammalian Epithelial Cells

inferredcites →https://doi.org/10.1093/emboj/20.14.3738openalex-snapshot

The cell polarity protein ASIP/PAR‐3 directly associates with junctional adhesion molecule (JAM)

inferredcites →https://doi.org/10.1093/emboj/cdg110openalex-snapshot

Structure of Cdc42 in a complex with the GTPase‐binding domain of the cell polarity protein, Par6

inferredcites →https://doi.org/10.1126/science.1072161openalex-snapshot

Composition and Formation of Intercellular Junctions in Epithelial Cells

inferredcites →https://doi.org/10.1126/science.1105718openalex-snapshot

Regulation of the Polarity Protein Par6 by TGFß Receptors Controls Epithelial Cell Plasticity

inferredcites →https://doi.org/10.1126/science.1105776openalex-snapshot

High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells

inferredcites →https://doi.org/10.1126/science.281.5385.2042openalex-snapshot

Protein Kinase C Isotypes Controlled by Phosphoinositide 3-Kinase Through the Protein Kinase PDK1

inferredcites →https://doi.org/10.1128/mcb.24.15.6665-6675.2004openalex-snapshot

Nucleotide Exchange Factor ECT2 Interacts with the Polarity Protein Complex Par6/Par3/Protein Kinase Cζ (PKCζ) and Regulates PKCζ Activity

inferredcites →https://doi.org/10.1146/annurev.cellbio.20.010403.103108openalex-snapshot

MECHANISMS OF POLARIZED GROWTH AND ORGANELLE SEGREGATION IN YEAST

inferredcites →https://doi.org/10.1146/annurev.cellbio.22.010305.104219openalex-snapshot

Tight Junctions and Cell Polarity

inferredcites →https://doi.org/10.1146/annurev.cellbio.22.010305.104340openalex-snapshot

The Cellular Basis of Kidney Development

inferredcites →https://doi.org/10.1146/annurev.genet.35.102401.091415openalex-snapshot

Epithelial Cell Polarity and Cell Junctions inDrosophila

inferredcites →https://doi.org/10.1146/annurev.physiol.65.092101.142517openalex-snapshot

Phosphoinositide Regulation of the Actin Cytoskeleton

inferredcites →https://doi.org/10.1152/ajpgi.00426.2003openalex-snapshot

sPAR-3, a splicing variant of PAR-3, shows cellular localization and an expression pattern different from that of PAR-3 during enterocyte polarization

inferredcites →https://doi.org/10.1152/physrev.1999.79.1.73openalex-snapshot

New Perspectives on Mechanisms Involved in Generating Epithelial Cell Polarity

inferredcites →https://doi.org/10.1242/dev.00648openalex-snapshot

Interaction of Par-6 and Crumbs complexes is essential for photoreceptor morphogenesis inDrosophila

inferredcites →https://doi.org/10.1242/dev.01907openalex-snapshot

The Snail genes as inducers of cell movement and survival: implications in development and cancer

inferredcites →https://doi.org/10.1242/dev.02182openalex-snapshot

Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesis

inferredcites →https://doi.org/10.1242/dev.122.3.951openalex-snapshot

The Drosophila genes crumbs and stardust are involved in the biogenesis of adherens junctions

inferredcites →https://doi.org/10.1242/dev.125.18.3607openalex-snapshot

Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans

inferredcites →https://doi.org/10.1242/jcs.00500openalex-snapshot

The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells

inferredcites →https://doi.org/10.1242/jcs.02412openalex-snapshot

Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells

inferredcites →https://doi.org/10.1242/jcs.02528openalex-snapshot

PATJ connects and stabilizes apical and lateral components of tight junctions in human intestinal cells

inferredcites →https://doi.org/10.1242/jcs.02560openalex-snapshot

Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells

inferredcites →https://doi.org/10.1242/jcs.02597openalex-snapshot

Apicobasal polarity complexes

inferredcites →https://doi.org/10.1242/jcs.02898openalex-snapshot

The PAR-aPKC system: lessons in polarity

inferredcites →https://doi.org/10.1242/jcs.113.18.3267openalex-snapshot

The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1

inferredcites →https://doi.org/10.1242/jcs.114.10.1829openalex-snapshot

Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites

inferredcites →https://doi.org/10.1515/bc.2004.116openalex-snapshot

Roles of nectins in cell adhesion, migration and polarization

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Prolactin and glucocorticoid signaling induces lactation-specific tight junctions concurrent with β-casein expression in mammary epithelial cells

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Coordinated regulation of cell differentiation by sphingosine-1-phosphate receptors in renal epithelial cells

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Molecular components of the adherens junction

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Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly

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inferred← citeshttps://doi.org/10.1016/j.cbpa.2009.02.035openalex-snapshot

Molecular and cellular regulation of water homeostasis in anuran amphibians by aquaporins

inferred← citeshttps://doi.org/10.1016/j.ceb.2008.01.001openalex-snapshot

Regulation of cell polarity during epithelial morphogenesis

inferred← citeshttps://doi.org/10.1016/j.conb.2012.04.003openalex-snapshot

Spindle orientation in mammalian cerebral cortical development

inferred← citeshttps://doi.org/10.1016/j.cub.2010.06.024openalex-snapshot

ASPP2 Regulates Epithelial Cell Polarity through the PAR Complex

inferred← citeshttps://doi.org/10.1016/j.devcel.2008.11.006openalex-snapshot

RETRACTED: Dystroglycan and Perlecan Provide a Basal Cue Required for Epithelial Polarity during Energetic Stress

inferred← citeshttps://doi.org/10.1016/j.devcel.2024.12.012openalex-snapshot

Assembly of tight junction belts by ZO1 surface condensation and local actin polymerization

inferred← citeshttps://doi.org/10.1016/j.ejphar.2016.07.018openalex-snapshot

Kidney-on-a-chip technology for renal proximal tubule tissue reconstruction

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.139759openalex-snapshot

Characterization of Choerospondias axillaris polysaccharide‑iron (III) complex and its effect on iron deficiency anemia mice

inferred← citeshttps://doi.org/10.1016/j.jtbi.2008.11.028openalex-snapshot

A mathematical model of α -catenin dimerization at adherens junctions in polarized epithelial cells

inferred← citeshttps://doi.org/10.1016/j.molcel.2021.07.021openalex-snapshot

A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies

inferred← citeshttps://doi.org/10.1016/j.phrs.2020.105115openalex-snapshot

Regulation of blood-retinal barrier cell-junctions in diabetic retinopathy

inferred← citeshttps://doi.org/10.1016/j.semcdb.2011.10.012openalex-snapshot

Non-SH2/PDZ reverse signaling by ephrins

inferred← citeshttps://doi.org/10.1016/j.tvr.2024.200277openalex-snapshot

E4orf1: The triple agent of adenovirus – Unraveling its roles in oncogenesis, infectious obesity and immune responses in virus replication and vector therapy

inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.02.032openalex-snapshot

Two novel EGFP insertion alleles reveal unique aspects of Pax2 function in embryonic and adult kidneys

inferred← citeshttps://doi.org/10.1016/j.ydbio.2019.05.008openalex-snapshot

Targeted deletion of Crb1/Crb2 in the optic vesicle models key features of leber congenital amaurosis 8

inferred← citeshttps://doi.org/10.1016/s1937-6448(08)02003-0openalex-snapshot

Chapter 3 Acquisition of Membrane Polarity in Epithelial Tube Formation

inferred← citeshttps://doi.org/10.1021/acs.biochem.5b01342openalex-snapshot

Binding of Crumbs to the Par-6 CRIB-PDZ Module Is Regulated by Cdc42

inferred← citeshttps://doi.org/10.1021/acs.jafc.5c00277openalex-snapshot

Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII

inferred← citeshttps://doi.org/10.1038/cr.2012.64openalex-snapshot

Polarized sorting and trafficking in epithelial cells

inferred← citeshttps://doi.org/10.1038/emboj.2009.190openalex-snapshot

Numb regulates cell–cell adhesion and polarity in response to tyrosine kinase signalling

inferred← citeshttps://doi.org/10.1038/ncb1758openalex-snapshot

EphrinB1 controls cell–cell junctions through the Par polarity complex

inferred← citeshttps://doi.org/10.1038/nrn3707openalex-snapshot

Growth and folding of the mammalian cerebral cortex: from molecules to malformations

inferred← citeshttps://doi.org/10.1038/onc.2008.347openalex-snapshot

Polarity proteins in migration and invasion

inferred← citeshttps://doi.org/10.1038/srep14504openalex-snapshot

CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium

inferred← citeshttps://doi.org/10.1042/bsr20100119openalex-snapshot

Apical protein transport and lumen morphogenesis in polarized epithelial cells

inferred← citeshttps://doi.org/10.1071/rd14187openalex-snapshot

Histochemical structure and immunolocalisation of the hyaluronan system in the dromedary oviduct

inferred← citeshttps://doi.org/10.1073/pnas.0910646107openalex-snapshot

Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor–dependent signaling pathways in renal collecting duct cells

inferred← citeshttps://doi.org/10.1074/jbc.ra119.010616openalex-snapshot

High-mobility group nucleosomal binding domain 2 protects against microcephaly by maintaining global chromatin accessibility during corticogenesis

inferred← citeshttps://doi.org/10.1080/19336918.2023.2260645openalex-snapshot

Scribble, Lgl1, and myosin IIA interact with α-/β-catenin to maintain epithelial junction integrity

inferred← citeshttps://doi.org/10.1080/21505594.2021.1966996openalex-snapshot

Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration

inferred← citeshttps://doi.org/10.1083/jcb.201007002openalex-snapshot

The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell–ECM signaling

inferred← citeshttps://doi.org/10.1089/thy.2018.0401openalex-snapshot

Primary Cilium in the Human Thyrocyte: Changes in Frequency and Length in Relation to the Functional Pathology of the Thyroid Gland

inferred← citeshttps://doi.org/10.1091/mbc.e09-02-0137openalex-snapshot

Trafficking of Crumbs3 during Cytokinesis Is Crucial for Lumen Formation

inferred← citeshttps://doi.org/10.1091/mbc.e10-04-0338openalex-snapshot

The SARS Coronavirus E Protein Interacts with PALS1 and Alters Tight Junction Formation and Epithelial Morphogenesis

inferred← citeshttps://doi.org/10.1091/mbc.e11-12-0988openalex-snapshot

PDK1 in apical signaling endosomes participates in the rescue of the polarity complex atypical PKC by intermediate filaments in intestinal epithelia

inferred← citeshttps://doi.org/10.1091/mbc.e22-04-0121openalex-snapshot

A novel tool for the unbiased characterization of epithelial monolayer development in culture

inferred← citeshttps://doi.org/10.1093/hmg/dds091openalex-snapshot

Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis

inferred← citeshttps://doi.org/10.1093/infdis/jit617openalex-snapshot

Clostridium difficile Toxins Facilitate Bacterial Colonization by Modulating the Fence and Gate Function of Colonic Epithelium

inferred← citeshttps://doi.org/10.1093/ismejo/wrag054openalex-snapshot

Cellular membrane protein MipA from E.coli Nissle 1917 protects against Salmonella infection

inferred← citeshttps://doi.org/10.1101/2023.06.24.546380openalex-snapshot

Assembly of Tight Junction Belts by Surface Condensation and Actin Elongation

inferred← citeshttps://doi.org/10.1101/cshperspect.a002923openalex-snapshot

Junctional Music that the Nucleus Hears: Cell-Cell Contact Signaling and the Modulation of Gene Activity

inferred← citeshttps://doi.org/10.1101/cshperspect.a004796openalex-snapshot

Phosphoinositides in Cell Architecture

inferred← citeshttps://doi.org/10.1101/cshperspect.a013789openalex-snapshot

Polarity in Mammalian Epithelial Morphogenesis

inferred← citeshttps://doi.org/10.1101/cshperspect.a027953openalex-snapshot

Targeting the Mucosal Barrier: How Pathogens Modulate the Cellular Polarity Network

inferred← citeshttps://doi.org/10.1111/j.1365-2443.2009.01315.xopenalex-snapshot

Intracellular polarity protein PAR‐1 regulates extracellular laminin assembly by regulating the dystroglycan complex

inferred← citeshttps://doi.org/10.1111/j.1600-0854.2010.01052.xopenalex-snapshot

Regulation of Tight Junction Assembly and Epithelial Polarity by a Resident Protein of Apical Endosomes

inferred← citeshttps://doi.org/10.1111/j.1742-4658.2012.08729.xopenalex-snapshot

The PDZ protein discs‐large ( DLG ): the ‘ J ekyll and H yde’ of the epithelial polarity proteins

inferred← citeshttps://doi.org/10.1111/jcmm.71124openalex-snapshot

CRB2 Facilitates Epithelial Ovarian Cancer Progression by Inducing Polarity Changes via Activation of the Wnt/ PCP Signalling Pathway

inferred← citeshttps://doi.org/10.1111/nyas.13367openalex-snapshot

Transcriptional mechanisms coordinating tight junction assembly during epithelial differentiation

inferred← citeshttps://doi.org/10.1113/jphysiol.2009.182246openalex-snapshot

Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers

inferred← citeshttps://doi.org/10.1126/sciadv.1700523openalex-snapshot

A tail of two voltages: Proteomic comparison of the three electric organs of the electric eel

inferred← citeshttps://doi.org/10.1126/scisignal.aag3209openalex-snapshot

PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeability

inferred← citeshttps://doi.org/10.1128/mcb.00999-13openalex-snapshot

Crumbs3 Is Essential for Proper Epithelial Development and Viability

inferred← citeshttps://doi.org/10.1128/mcb.01505-08openalex-snapshot

Similar and Distinct Properties of MUPP1 and Patj, Two Homologous PDZ Domain-Containing Tight-Junction Proteins

inferred← citeshttps://doi.org/10.1152/ajpcell.00069.2022openalex-snapshot

The basement membrane in epidermal polarity, stemness, and regeneration

inferred← citeshttps://doi.org/10.1155/2018/1309746openalex-snapshot

Airway Epithelium Dysfunction in Cystic Fibrosis and COPD

inferred← citeshttps://doi.org/10.1165/rcmb.2013-0541rtopenalex-snapshot

Breaking Barriers. New Insights into Airway Epithelial Barrier Function in Health and Disease

inferred← citeshttps://doi.org/10.1167/iovs.09-4520openalex-snapshot

Restricted Localization of Ponli, a Novel Zebrafish MAGUK-Family Protein, to the Inner Segment Interface Areas between Green, Red, and Blue Cones

inferred← citeshttps://doi.org/10.1177/1933719116648216openalex-snapshot

Nectin-3 Is Increased in the Cell Junctions of the Uterine Epithelium at Implantation

inferred← citeshttps://doi.org/10.1186/s13014-023-02241-4openalex-snapshot

Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data

inferred← citeshttps://doi.org/10.1210/en.2009-0427openalex-snapshot

14-3-3 Protein Regulates Cell Adhesion in the Seminiferous Epithelium of Rat Testes

inferred← citeshttps://doi.org/10.1210/me.2014-1037openalex-snapshot

Minireview: Steroid/Nuclear Receptor-Regulated Dynamics of Occluding and Anchoring Junctions

inferred← citeshttps://doi.org/10.1242/bio.20135918openalex-snapshot

Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells

inferred← citeshttps://doi.org/10.1242/dev.055483openalex-snapshot

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex

inferred← citeshttps://doi.org/10.1242/dev.059980openalex-snapshot

Apical deficiency triggers JNK-dependent apoptosis in the embryonic epidermis of Drosophila

inferred← citeshttps://doi.org/10.1242/dev.083162openalex-snapshot

Drosophila Patj plays a supporting role in apical-basal polarity but is essential for viability

inferred← citeshttps://doi.org/10.1242/jcs.023887openalex-snapshot

Tight junctions at a glance

inferred← citeshttps://doi.org/10.1242/jcs.032615openalex-snapshot

Apical trafficking in epithelial cells: signals, clusters and motors

inferred← citeshttps://doi.org/10.1242/jcs.057752openalex-snapshot

Epithelial cell shape is regulated by Lulu proteins via myosin-II

inferred← citeshttps://doi.org/10.1242/jcs.086694openalex-snapshot

Differential regulation of adherens junction dynamics during apical–basal polarization

inferred← citeshttps://doi.org/10.1242/jcs.261150openalex-snapshot

Centrosome amplification promotes cell invasion via cell–cell contact disruption and Rap-1 activation

inferred← citeshttps://doi.org/10.1371/journal.pone.0009938openalex-snapshot

A Modifier Screen for Bazooka/PAR-3 Interacting Genes in the Drosophila Embryo Epithelium

inferred← citeshttps://doi.org/10.1371/journal.pone.0099269openalex-snapshot

Gene Expression Correlations in Human Cancer Cell Lines Define Molecular Interaction Networks for Epithelial Phenotype

inferred← citeshttps://doi.org/10.1371/journal.pone.0165225openalex-snapshot

An Optimised Human Cell Culture Model for Alveolar Epithelial Transport

inferred← citeshttps://doi.org/10.1523/jneurosci.1880-09.2009openalex-snapshot

Stepwise Maturation of Apicobasal Polarity of the Neuroepithelium Is Essential for Vertebrate Neurulation

inferred← citeshttps://doi.org/10.1523/jneurosci.5185-09.2010openalex-snapshot

Pals1 Is a Major Regulator of the Epithelial-Like Polarization and the Extension of the Myelin Sheath in Peripheral Nerves

inferred← citeshttps://doi.org/10.1534/g3.116.028886openalex-snapshot

Partial Functional Diversification ofDrosophila melanogasterSeptin GenesSep2andSep5

inferred← citeshttps://doi.org/10.1681/asn.2008090949openalex-snapshot

Apical Lumen Formation in Renal Epithelia

inferred← citeshttps://doi.org/10.1681/asn.2008121233openalex-snapshot

Urinary Peptidome May Predict Renal Function Decline in Type 1 Diabetes and Microalbuminuria

inferred← citeshttps://doi.org/10.1681/asn.2010010061openalex-snapshot

ZO-1 and ZONAB Interact to Regulate Proximal Tubular Cell Differentiation

inferred← citeshttps://doi.org/10.21203/rs.3.rs-3351881/v1openalex-snapshot

Assembly of tight junction belts by surface condensation and actin elongation

inferred← citeshttps://doi.org/10.2741/3316openalex-snapshot

The assembly and maintenance of epithelial junctions in C. elegans

inferred← citeshttps://doi.org/10.2741/3368openalex-snapshot

Crumbs proteins in epithelial morphogenesis

inferred← citeshttps://doi.org/10.2741/3939openalex-snapshot

Eph/ephrin signaling in cell-cell and cell-substrate adhesion

inferred← citeshttps://doi.org/10.30789/rcneumologia.v26.n3.2014.38openalex-snapshot

La membrana alveolo-capilar

inferred← citeshttps://doi.org/10.3389/fcell.2022.948013openalex-snapshot

Rho and Rab Family Small GTPases in the Regulation of Membrane Polarity in Epithelial Cells

inferred← citeshttps://doi.org/10.3389/fgene.2020.00248openalex-snapshot

Application and Comparison of Supervised Learning Strategies to Classify Polarity of Epithelial Cell Spheroids in 3D Culture

inferred← citeshttps://doi.org/10.3389/fmicb.2011.00114openalex-snapshot

Subversion of Mucosal Barrier Polarity by Pseudomonas Aeruginosa

inferred← citeshttps://doi.org/10.3389/fmicb.2019.01740openalex-snapshot

Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection

inferred← citeshttps://doi.org/10.3389/fmolb.2020.00001openalex-snapshot

Characterizing the Binding Sites for GK Domain of DLG1 and DLG4 via Molecular Dynamics Simulation

inferred← citeshttps://doi.org/10.3389/fnins.2014.00392openalex-snapshot

“You Shall Not Pass”—tight junctions of the blood brain barrier

inferred← citeshttps://doi.org/10.3390/ijms262311551openalex-snapshot

The Specific Pathogenicity Pattern of the Different CRB1 Isoforms Conditions Clinical Severity in Inherited Retinal Dystrophies

inferred← citeshttps://doi.org/10.3390/microorganisms11051223openalex-snapshot

Association between Intestinal Microecological Changes and Atherothrombosis

inferred← citeshttps://doi.org/10.3410/f.1981956.2991057openalex-snapshot

Faculty Opinions recommendation of Quantitative phosphoproteomic analysis reveals vasopressin V2-receptor-dependent signaling pathways in renal collecting duct cells.

inferred← citeshttps://doi.org/10.3724/sp.j.1005.2013.00281openalex-snapshot

Par polarity complex in mammalian neurogenesis

inferred← citeshttps://doi.org/10.4161/cam.3.3.8211openalex-snapshot

EphrinB reverse signaling in cell-cell adhesion

inferred← citeshttps://doi.org/10.4161/gmic.23797openalex-snapshot

Polymorphism in the Helicobacter pylori CagA and VacA toxins and disease

inferred← citeshttps://doi.org/10.4161/org.7.3.17084openalex-snapshot

The Ran importin system in cilia trafficking

inferred← citeshttps://doi.org/10.4161/tisb.24997openalex-snapshot

Barrier function of airway tract epithelium

inferred← citeshttps://doi.org/10.4161/tisb.25039openalex-snapshot

Beyond cell-cell adhesion

inferred← citeshttps://doi.org/10.5402/2012/769412openalex-snapshot

Polarization and Myelination in Myelinating Glia

inferred← citeshttps://doi.org/10.5772/35115openalex-snapshot

Development and Cell Polarity of the C. elegans Intestine

inferred← citeshttps://doi.org/10.70675/4042eb4fz7dbfz4465za1bez63d3149b21d5openalex-snapshot

Identification and functional characterization of a novel Scribble phosphorylation site

inferred← citeshttps://doi.org/10.70675/43850d09z0edcz4cb3zb3b1z4ba5179a6754openalex-snapshot

Identification and characterization of the mechanical role of germline growth in Drosophila melanogaster epithelial morphogenesis

inferred← citeshttps://doi.org/10.70675/4f780c71z93e2z4c5fz848dz229cf7399d87openalex-snapshot

L’inhibition de PDZRN3 est requise pour la maturation cardiomyocytaire post-natal et protège de l’insuffisance cardiaque

inferred← citeshttps://doi.org/10.70675/93458201z9adaz4e3ez8e58z29bca2b7194fopenalex-snapshot

Étude moléculaire et ciblage de la protéine de la polarité planaire VANGL2 dans les cancers du sein

inferred← citeshttps://doi.org/10.7554/elife.78779openalex-snapshot

Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation

inferred← citeshttps://doi.org/10.82444/warw.33757513openalex-snapshot

Pathways that regulate renal development, fibrosis, and metabolic disease in mouse models

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