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CancerDR: Cancer Drug Resistance Database

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/0471140864.ps0209s50openalex-snapshot
Comparative Protein Structure Modeling Using MODELLER
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Comparative Protein Structure Modeling Using Modeller
inferredcites →https://doi.org/10.1002/bip.360221211openalex-snapshot
Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features
inferredcites →https://doi.org/10.1002/prot.20921openalex-snapshot
MUSTANG: A multiple structural alignment algorithm
inferredcites →https://doi.org/10.1006/jmbi.1990.9999openalex-snapshot
Basic Local Alignment Search Tool
inferredcites →https://doi.org/10.1016/s0002-9459(24)07757-xopenalex-snapshot
The Pharmacology of HIV Drug Resistance
inferredcites →https://doi.org/10.1016/s1574-1400(08)00012-1openalex-snapshot
PubChem: Integrated Platform of Small Molecules and Biological Activities
inferredcites →https://doi.org/10.1038/nature10983openalex-snapshot
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
inferredcites →https://doi.org/10.1038/nature11003openalex-snapshot
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
inferredcites →https://doi.org/10.1038/nature11005openalex-snapshot
Systematic identification of genomic markers of drug sensitivity in cancer cells
inferredcites →https://doi.org/10.1038/nm.2323openalex-snapshot
Cancer genomics: from discovery science to personalized medicine
inferredcites →https://doi.org/10.1038/nmeth.1818openalex-snapshot
HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment
inferredcites →https://doi.org/10.1038/nrc3297openalex-snapshot
Managing drug resistance in cancer: lessons from HIV therapy
inferredcites →https://doi.org/10.1038/nrclinonc.2010.222openalex-snapshot
Implications of personalized medicine—perspective from a cancer center
inferredcites →https://doi.org/10.1038/nrclinonc.2011.126openalex-snapshot
Personalized medicine in lung cancer: what we need to know
inferredcites →https://doi.org/10.1093/bioinformatics/btp134openalex-snapshot
The calibrated population resistance tool: standardized genotypic estimation of transmitted HIV-1 drug resistance
inferredcites →https://doi.org/10.1093/bioinformatics/btp324openalex-snapshot
Fast and accurate short read alignment with Burrows–Wheeler transform
inferredcites →https://doi.org/10.1093/bioinformatics/btp352openalex-snapshot
The Sequence Alignment/Map format and SAMtools
inferredcites →https://doi.org/10.1093/bioinformatics/btp666openalex-snapshot
Tablet—next generation sequence assembly visualization
inferredcites →https://doi.org/10.1093/bioinformatics/btr304openalex-snapshot
Java bioinformatics analysis web services for multiple sequence alignment—JABAWS:MSA
inferredcites →https://doi.org/10.1093/nar/22.22.4673openalex-snapshot
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
inferredcites →https://doi.org/10.1093/nar/27.1.348openalex-snapshot
Human Immunodeficiency Virus Reverse Transcriptase and Protease Sequence Database
inferredcites →https://doi.org/10.1093/nar/30.1.412openalex-snapshot
TTD: Therapeutic Target Database
inferredcites →https://doi.org/10.1093/nar/gkg100openalex-snapshot
Human immunodeficiency virus reverse transcriptase and protease sequence database
inferredcites →https://doi.org/10.1093/nar/gkh379openalex-snapshot
AUGUSTUS: a web server for gene finding in eukaryotes
inferredcites →https://doi.org/10.1107/s0021889892009944openalex-snapshot
PROCHECK: a program to check the stereochemical quality of protein structures
inferredcites →https://doi.org/10.1111/j.1600-0463.2007.apm_636.xml.xopenalex-snapshot
Epigenetic changes in cancer
inferredcites →https://doi.org/10.1158/0008-5472.can-10-4351openalex-snapshot
Identification of the MEK1(F129L) Activating Mutation as a Potential Mechanism of Acquired Resistance to MEK Inhibition in Human Cancers Carrying the B-Raf V600E Mutation
inferredcites →https://doi.org/10.1159/000331998openalex-snapshot
The HIVdb System for HIV-1 Genotypic Resistance Interpretation
inferredcites →https://doi.org/10.1177/153303460500400608openalex-snapshot
Role of Nanobiotechnology in Developing Personalized Medicine for Cancer
inferredcites →https://doi.org/10.2174/092986607781483859openalex-snapshot
PEPstr: A de novo Method for Tertiary Structure Prediction of Small Bioactive Peptides
inferredcites →https://doi.org/10.2174/138920208785699580openalex-snapshot
Cause and Consequences of Genetic and Epigenetic Alterations in Human Cancer

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Drug T arget I nspector: An assistance tool for patient treatment stratification
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Structural basis for drug resistance mechanisms against anaplastic lymphoma kinase
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Current advances in ligand‐based target prediction
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Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development
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Managing Drug Resistance in Cancer: Role of Cancer Informatics
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Free Energy-Based Methods to Understand Drug Resistance Mutations
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Drug Dosage Balancing Using Large Scale Multi-omics Datasets
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Omics: A Holistic Approach in Cancer Treatment
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CADD for Cancer Therapy: Current and Future Perspective
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Atomistic insights into the lung cancer-associated L755P mutation in HER2 resistance to lapatinib: a molecular dynamics study
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Computationally unraveling how ceritinib overcomes drug-resistance mutations in ALK-rearranged lung cancer
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Cancer pharmacoinformatics: Databases and analytical tools
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The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to γ-rays and/or erlotinib
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Applications of artificial intelligence to drug design and discovery in the big data era: a comprehensive review
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A Comprehensive Review on Deep Synergistic Drug Prediction Techniques for Cancer
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India’s Computational Biology Growth and Challenges
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Computational Approaches and Resources in Single Amino Acid Substitutions Analysis Toward Clinical Research
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Translational Bioinformatics Methods for Drug Discovery and Development
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Unveiling potential anticancer drugs through in silico drug repurposing approaches
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Retrieval of compounds
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Translational bioinformatics methods for drug discovery and drug repurposing
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Therapeutic potentials of medicinal plants and significance of computational tools in anti-cancer drug discovery
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In silico-assisted prediction of chemoresistance
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Artificial intelligence and machine learning approaches in rational drug design to overcome cancer chemoresistance
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2021.11.008openalex-snapshot
In silico tools and databases for designing cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.abb.2020.108571openalex-snapshot
TAZ-regulated expression of IL-8 is involved in chemoresistance of hepatocellular carcinoma cells
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Artificial intelligence in the early stages of drug discovery
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Deep learning-based discovery of tetrahydrocarbazoles as broad-spectrum antitumor agents and click-activated strategy for targeted cancer therapy
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Coevolution-based computational approach to detect resistance mechanism of epidermal growth factor receptor
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Association analysis of the perturbation of interactions in biological pathways and anticancer drug activity
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Design, synthesis and in vitro anticancer research of novel tetrandrine and fangchinoline derivatives
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Integrating bioassay data for improved prediction of drug-target interaction
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Design, synthesis, in vitro anticancer evaluation, in silico molecular docking and ADMET profiling of carbohydrate-conjugated pyridine oximes
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Oncology drug resistance prediction tools: Database infrastructure, algorithmic innovation, and clinical translation
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Human drug-pathway association prediction based on network consistency projection
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Coevolutionary dynamics of 53BP1 and its impact on TP53 interaction for DNA damage repair
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In silico resources help combat cancer drug resistance mediated by target mutations
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Network biology and artificial intelligence drive the understanding of the multidrug resistance phenotype in cancer
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New imidazo[1,2-b]pyrazoles as anticancer agents: Synthesis, biological evaluation and structure activity relationship analysis
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Downregulation of miR-21 as a promising strategy to overcome drug resistance in cancer
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Prospect for application of mathematical models in combination cancer treatments
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Substituting one Paris for another? In vitro cytotoxic and in vivo antitumor activities of Paris forrestii , a substitute of Paris polyphylla var. yunnanensis
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Identification of imidazo[1,2-a]pyridines-pyrazole-pyran hybrids as potent glucose-6-phosphate dehydrogenase (G6PD) inhibitors: Synthesis, molecular docking, DFT studies and ADME prediction
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Synthesis of Novel Thiourea-based Benzamide Derivatives as Potential Anticancer Agents: DFT-Assisted Molecular Docking against Cancerous Target Protein and ADMET Prediction
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Heat-Shock Protein 90–Targeted Nano Anticancer Therapy
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Advances in small molecule representations and AI-driven drug research: bridging the gap between theory and application
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HNCDrugResDb: a platform for deciphering drug resistance in head and neck cancers
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PCMdb: Pancreatic Cancer Methylation Database
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Herceptin Resistance Database for Understanding Mechanism of Resistance in Breast Cancer Patients
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Designing of promiscuous inhibitors against pancreatic cancer cell lines
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CancerHSP: anticancer herbs database of systems pharmacology
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High-velocity deformation of Al0.3CoCrFeNi high-entropy alloy: Remarkable resistance to shear failure
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GEAR: A database of Genomic Elements Associated with drug Resistance
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The unequivocal preponderance of biocomputation in clinical virology
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Towards the routine use of in silico screenings for drug discovery using metabolic modelling
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Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing
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Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells
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Computational resources for identification of cancer biomarkers from omics data
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Drug-pathway association prediction: from experimental results to computational models
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A multiple network-based bioinformatics pipeline for the study of molecular mechanisms in oncological diseases for personalized medicine
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Machine learning methods, databases and tools for drug combination prediction
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Bioinformatics toolbox for exploring target mutation-induced drug resistance
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Bio/chemoinformatics in India: an outlook
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Drug–target interaction prediction: databases, web servers and computational models
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Mathematical modeling and computational prediction of cancer drug resistance
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Methods and resources to access mutation-dependent effects on cancer drug treatment
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RNAactDrug: a comprehensive database of RNAs associated with drug sensitivity from multi-omics data
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FourierDrug: a domain generalization framework for robust drug response prediction via frequency-space asymmetric attention
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Incorporating prior information into differential network analysis using non-paranormal graphical models
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Database of evidence for precision oncology portal
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HCDT: an integrated highly confident drug–target resource
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DRESIS: the first comprehensive landscape of drug resistance information
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DRMref: comprehensive reference map of drug resistance mechanisms in human cancer
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Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes
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CancerResource—updated database of cancer-relevant proteins, mutations and interacting drugs
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GDA, a web-based tool for Genomics and Drugs integrated analysis
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Bioinformatics tools and resources for cancer and application
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Prediction of Drug Resistance Mechanisms: Integration of Molecular Modeling and Artificial Intelligence Methods
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HCMdrugs: A Web-Based Database Cataloging the Drugs Available for the Treatment of Hypertrophic Cardiomyopathy
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Biomolecular Network-Based Synergistic Drug Combination Discovery
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Drug Response Prediction Based on 1D Convolutional Neural Network and Attention Mechanism
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Identification of Herb Pairs in Esophageal Cancer
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A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening
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Identification and characterization of genes with absolute mRNA abundances changes in tumor cells with varied transcriptome sizes
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Emerging artificial intelligence-driven precision therapies in tumor drug resistance: recent advances, opportunities, and challenges
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Identifying subpathway signatures for individualized anticancer drug response by integrating multi-omics data
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Integrative omics analyses broaden treatment targets in human cancer
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KRDS: a web server for evaluating drug resistance mutations in kinases by molecular docking
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Prediction of drug cocktail effects when the number of measurements is limited
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CDRgator: An Integrative Navigator of Cancer Drug Resistance Gene Signatures.
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Ranking novel cancer driving synthetic lethal gene pairs using TCGA data
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Bet Hedging in Pdr5-mediated Drug Resistance and a Mechanism for its Regulation
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Systematic Analysis of the Therapy Resistance Genes and their Prognostic Relevance in Cervical Cancer
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Artificial Intelligence: An Emerging Intellectual Sword for Battling Carcinomas
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Network Pharmacology: Exploring the Resources and Methodologies
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Topoisomerase and Tyrosyl-DNA-phosphodiesterase Ratio as an Indicator for the Response of Glioblastoma Cancer to Topoisomerase Targeting Anticancer Drugs
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Context Matters—Why We Need to Change From a One Size Fits all Approach to Made-to-Measure Therapies for Individual Patients With Pancreatic Cancer
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Inferring Differential Networks by Integrating Gene Expression Data With Additional Knowledge
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Revolutionizing adjuvant development: harnessing AI for next-generation cancer vaccines
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Pan-cancer evaluation of clinical value of mitotic network activity index (MNAI) and its predictive value for immunotherapy
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In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR
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Systems Pharmacology for Investigation of the Mechanisms of Action of Traditional Chinese Medicine in Drug Discovery
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Linked Data for Life Sciences
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An Updated Overview of Existing Cancer Databases and Identified Needs
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Biomolecule and Bioentity Interaction Databases in Systems Biology: A Comprehensive Review
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Network Analysis Identifies Drug Targets and Small Molecules to Modulate Apoptosis Resistant Cancers
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Nanoplatform for the Delivery of Topotecan in the Cancer Milieu: An Appraisal of its Therapeutic Efficacy
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Machine Learning Based Toxicity Prediction: From Chemical Structural Description to Transcriptome Analysis
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Cytarabine-Resistant FLT3-ITD Leukemia Cells are Associated with TP53 Mutation and Multiple Pathway Alterations—Possible Therapeutic Efficacy of Cabozantinib
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Addressing Drug Resistance in Cancer: A Team Medicine Approach
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Systems Biology and Experimental Model Systems of Cancer
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An Improved High Yield Total Synthesis and Cytotoxicity Study of the Marine Alkaloid Neoamphimedine: An ATP-Competitive Inhibitor of Topoisomerase IIα and Potent Anticancer Agent
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Machine Learning for Drug-Target Interaction Prediction
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Synthesis and Characterization of the Conjugated Peptide Lunatin-Folate
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New Drug Development and Clinical Trial Design by Applying Genomic Information Management
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Mitochondria targeting and near-infrared fluorescence imaging of a novel heptamethine cyanine anticancer agent
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Human cancer databases (Review)
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The Hidden Costs of Intelligence
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Application of Computer Modeling to Drug Discovery: Case Study of PRK1 Kinase Inhibitors as Potential Drugs in Prostate Cancer Treatment
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Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
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Drug Repurposing in Oncotherapeutics
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Anti-angiogenic and cytotoxic activities of rotenoids from Derris trifoliata Lour.
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AptCancerDB: A Curated Knowledgebase and Translational Discovery Platform for Anticancer Aptamers
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Drug Target Interaction Prediction Using Machine Learning Techniques – A Review.
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.