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Fine-tuning the chemo- and regioselective alkylation of 1,4-benzodiazepines: further applications of the Mitsunobu reaction

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Click Chemistry: Diverse Chemical Function from a Few Good Reactions
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inferredcites →https://doi.org/10.1002/adma.201302365openalex-snapshot
Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation‐Induced Emission
inferredcites →https://doi.org/10.1002/anie.201007100openalex-snapshot
Farewell to the HSAB Treatment of Ambident Reactivity
inferredcites →https://doi.org/10.1016/j.ab.2005.07.026openalex-snapshot
Enhanced sensitivity and precision in an enzyme-linked immunosorbent assay with fluorogenic substrates compared with commonly used chromogenic substrates
inferredcites →https://doi.org/10.1016/j.bios.2010.12.041openalex-snapshot
A novel system combining biocatalytic dephosphorylation of l-ascorbic acid 2-phosphate and electrochemical oxidation of resulting ascorbic acid
inferredcites →https://doi.org/10.1016/j.bmcl.2006.03.055openalex-snapshot
Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein–protein interaction through structure-based drug design
inferredcites →https://doi.org/10.1016/j.tet.2010.03.118openalex-snapshot
Concise access to N9-mono-, N2-mono- and N2,N9-di-substituted guanines via efficient Mitsunobu reactions
inferredcites →https://doi.org/10.1016/s0039-9140(01)00378-2openalex-snapshot
Detection of zeptomolar concentrations of alkaline phosphatase based on a tyrosinase and horse-radish peroxidase bienzyme biosensor
inferredcites →https://doi.org/10.1016/s0040-4020(01)90217-0openalex-snapshot
Protein β-turn mimetics I. Design, synthesis, and evaluation in model cyclic peptides.
inferredcites →https://doi.org/10.1016/s0040-4039(00)00115-5openalex-snapshot
A facile KF/Al2O3 mediated, selective alkylation of benzodiazepin-2,5-diones
inferredcites →https://doi.org/10.1016/s0040-4039(00)76633-0openalex-snapshot
N- vs. O-alkylation in the mitsunobu reaction of 2-pyridone
inferredcites →https://doi.org/10.1021/ac9002722openalex-snapshot
Convenient and Continuous Fluorometric Assay Method for Acetylcholinesterase and Inhibitor Screening Based on the Aggregation-Induced Emission
inferredcites →https://doi.org/10.1021/cr020033sopenalex-snapshot
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
inferredcites →https://doi.org/10.1021/cr800278zopenalex-snapshot
Mitsunobu and Related Reactions: Advances and Applications
inferredcites →https://doi.org/10.1021/ja00891a024openalex-snapshot
Solvation as a Factor in the Alkylation of Ambident Anions: The Importance of the Hydrogen Bonding Capacity of the Solvent
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Hard and Soft Acids and Bases
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Application of the Principle of Hard and Soft Acids and Bases to Organic Chemistry
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CHEMICAL EFFECTS ARISING FROM SELECTIVE SOLVATION: SELECTIVE SOLVATION AS A FACTOR IN THE ALKYLATION OF AMBIDENT ANIONS
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Fluorescent Chemosensor for Detection and Quantitation of Carbon Dioxide Gas
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Real-Time Monitoring of Cell Apoptosis and Drug Screening Using Fluorescent Light-Up Probe with Aggregation-Induced Emission Characteristics
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Full-Range Intracellular pH Sensing by an Aggregation-Induced Emission-Active Two-Channel Ratiometric Fluorogen
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Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists
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Nucleophilic Reactivities of Imide and Amide Anions
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Practical synthesis of potential endothelin receptor antagonists of 1,4-benzodiazepine-2,5-dione derivatives bearing substituents at the C 3 -, N 1 - and N 4 -positions
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Nanoparticle-based immunoassays in the biomedical field
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Small-molecule inhibitors of dimeric transcription factors: Antagonism of protein–protein and protein–DNA interactions
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A ratiometric fluorescent probe for hydrophobic proteins in aqueous solution based on aggregation-induced emission
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Biosensor technology: recent advances in threat agent detection and medicine
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Plasmonic nanomaterials for biodiagnostics
inferredcites →https://doi.org/10.1111/j.1747-0285.2006.00365.xopenalex-snapshot
Substituted 1,4‐Benzodiazepine‐2,5‐diones as α‐Helix Mimetic Antagonists of the HDM2‐p53 Protein–Protein Interaction

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4652924openalex-extracted
inferred← citeshttps://doi.org/10.1007/s41061-025-00501-3openalex-snapshot
Recent Advances in the Mitsunobu and Related Reactions: A Review from 2010 to 2024
inferred← citeshttps://doi.org/10.1016/b978-0-323-96025-0.00004-1openalex-snapshot
Synthesis of Amines and Ammonium Salts
inferred← citeshttps://doi.org/10.1016/j.rechem.2024.101366openalex-snapshot
L-Aspartic acid pyridinium salts: In silico, synthesis and adjuvant vs antibiotic antibacterial evaluation
inferred← citeshttps://doi.org/10.1016/j.tet.2016.10.022openalex-snapshot
Synthesis of 4-alkylsulfanylphthalazin-1(2H)-ones via palladium catalyzed sulfanylation of substituted 4-bromophthalazin-1(2H)-ones
inferred← citeshttps://doi.org/10.1016/j.tetlet.2013.06.049openalex-snapshot
Azodicarbonyl dimorpholide (ADDM): an effective, versatile, and water-soluble Mitsunobu reagent
inferred← citeshttps://doi.org/10.1016/j.tetlet.2014.01.065openalex-snapshot
O-Alkylation of 3-hydroxyisoxazoles predominates under Mitsunobu conditions
inferred← citeshttps://doi.org/10.1016/j.tetlet.2016.10.045openalex-snapshot
Chromatography-free, Mitsunobu-triggered heterocyclizations of salicylhydroxamic acids to 3-hydroxybenzisoxazoles
inferred← citeshttps://doi.org/10.1021/acs.iecr.4c03657openalex-snapshot
Efficient N-Alkylation of Secondary Amines to Prepare N-Butyl-1,2-benzisothiazolin-3-one Based on Cs Ion Effect with Cs/LTA Zeolite Catalysts
inferred← citeshttps://doi.org/10.1021/jo502396uopenalex-snapshot
Chromatography-Free Entry to Substituted Salicylonitriles: Mitsunobu-Triggered Domino Reactions of Salicylaldoximes
inferred← citeshttps://doi.org/10.1039/9781782624011-00001openalex-snapshot
Synthetic Approaches and Challenges to Transcription Factor Inhibitors
inferred← citeshttps://doi.org/10.1039/c5qo00016eopenalex-snapshot
The Mitsunobu reaction in the 21 st century
inferred← citeshttps://doi.org/10.1039/d1cc02472hopenalex-snapshot
Straightforward N -alkylation of diketopyrrolopyrroles through the Mitsunobu reaction with benzyl, α-branched, and chiral alcohols
inferred← citeshttps://doi.org/10.24820/ark.5550190.p010.937openalex-snapshot
Convenient approach to novel tetracyclic-fused pyranoquinolinone compounds from 6-n‐butyl‐3‐amino-4-hydroxypyrano[3,2‐c]quinolinone
inferred← citeshttps://doi.org/10.4155/fmc.13.176openalex-snapshot
Recapitulating the α-Helix: Nonpeptidic, Low-Molecular-Weight Ligands for the Modulation of Helix-Mediated Protein–Protein Interactions
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