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Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.200702700openalex-snapshot

Total Synthesis of (−)‐Episilvestrol and (−)‐Silvestrol

inferredcites →https://doi.org/10.1002/anie.200702707openalex-snapshot

Enantioselective Synthesis of the Complex Rocaglate (−)‐Silvestrol

inferredcites →https://doi.org/10.1002/anie.201003212openalex-snapshot

Biomimetic Photocycloaddition of 3‐Hydroxyflavones: Synthesis and Evaluation of Rocaglate Derivatives as Inhibitors of Eukaryotic Translation

inferredcites →https://doi.org/10.1002/ijc.22883openalex-snapshot

The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen‐activated protein kinase activities

inferredcites →https://doi.org/10.1002/ijc.28521openalex-snapshot

The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints

inferredcites →https://doi.org/10.1007/978-3-319-59542-9openalex-snapshot

Progress in the Chemistry of Organic Natural Products 106

inferredcites →https://doi.org/10.1007/978-3-7091-0748-5_1openalex-snapshot

Chemistry and Biology of Rocaglamides (= Flavaglines) and Related Derivatives from Aglaia Species (Meliaceae)

inferredcites →https://doi.org/10.1016/0040-4020(96)00322-5openalex-snapshot

New nitrogenous and aromatic derivatives from Aglaia argentea and A. forbesii

inferredcites →https://doi.org/10.1016/j.bmc.2005.09.012openalex-snapshot

Activity-guided isolation of cytotoxic constituents from the bark of Aglaia crassinervia collected in Indonesia

inferredcites →https://doi.org/10.1016/j.bmc.2011.10.048openalex-snapshot

Recent advances in the biology and chemistry of the flavaglines

inferredcites →https://doi.org/10.1016/j.bmcl.2006.09.084openalex-snapshot

Ponapensin, a cyclopenta[bc]benzopyran with potent NF-κB inhibitory activity from Aglaia ponapensis

inferredcites →https://doi.org/10.1016/j.chembiol.2012.07.012openalex-snapshot

The Natural Anticancer Compounds Rocaglamides Inhibit the Raf-MEK-ERK Pathway by Targeting Prohibitin 1 and 2

inferredcites →https://doi.org/10.1016/j.chembiol.2013.02.006openalex-snapshot

Prohibitin Ligands in Cell Death and Survival: Mode of Action and Therapeutic Potential

inferredcites →https://doi.org/10.1016/j.leukres.2009.07.043openalex-snapshot

Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells

inferredcites →https://doi.org/10.1016/j.pestbp.2013.09.001openalex-snapshot

Prohibitin, an essential protein for Colorado potato beetle larval viability, is relevant to Bacillus thuringiensis Cry3Aa toxicity

inferredcites →https://doi.org/10.1016/j.phytochem.2007.06.016openalex-snapshot

Flavaglines and triterpenoids from the leaves of Aglaia forbesii

inferredcites →https://doi.org/10.1016/j.phytochem.2007.10.015openalex-snapshot

Amide-esters from Aglaia tenuicaulis – First representatives of a class of compounds structurally related to bisamides and flavaglines

inferredcites →https://doi.org/10.1016/j.phytol.2012.10.003openalex-snapshot

Two new rocaglamide derivatives from twigs of Aglaia odorata var. microphyllina

inferredcites →https://doi.org/10.1016/j.tet.2007.05.074openalex-snapshot

Constituents of the leaves and stem bark of Aglaia foveolata

inferredcites →https://doi.org/10.1016/s0009-2797(98)00073-8openalex-snapshot

Cytostatic mechanism and antitumor potential of novel 1H-cyclopenta[b]benzofuran lignans isolated from Aglaiaelliptica

inferredcites →https://doi.org/10.1016/s0031-9422(00)00471-4openalex-snapshot

Insecticidal flavaglines and other compounds from Fijian Aglaia species

inferredcites →https://doi.org/10.1016/s0031-9422(01)00186-8openalex-snapshot

Stress induced carbazole phytoalexins in Glycosmis species

inferredcites →https://doi.org/10.1016/s0031-9422(97)00253-7openalex-snapshot

Insecticidal rocaglamide derivatives from Aglaia elliptica and A. harmsiana

inferredcites →https://doi.org/10.1016/s0031-9422(98)00751-1openalex-snapshot

An insecticidal rocaglamide derivatives and related compounds from Aglaia odorata (Meliaceae)

inferredcites →https://doi.org/10.1016/s0031-9422(99)00185-5openalex-snapshot

Thapsakins: possible biogenetic intermediates towards insecticidal cyclopenta[b]benzofurans from Aglaia edulis

inferredcites →https://doi.org/10.1016/s0040-4020(97)10231-9openalex-snapshot

Novel cytotoxic 1H-cyclopenta[b]benzofuran lignans from Aglaia elliptica

inferredcites →https://doi.org/10.1016/s0040-4039(01)01807-xopenalex-snapshot

Total synthesis of (±)-rocaglamide and some aryl analogues

inferredcites →https://doi.org/10.1017/s135583820100108xopenalex-snapshot

The requirement for eukaryotic initiation factor 4A (eIF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure

inferredcites →https://doi.org/10.1021/cb400158topenalex-snapshot

Evidence for a Functionally Relevant Rocaglamide Binding Site on the eIF4A–RNA Complex

inferredcites →https://doi.org/10.1021/ja00180a081openalex-snapshot

An unusual oxidative cyclization. A synthesis and absolute stereochemical assignment of (-)-rocaglamide

inferredcites →https://doi.org/10.1021/ja044798oopenalex-snapshot

A Biomimetic Approach to the Rocaglamides Employing Photogeneration of Oxidopyryliums Derived from 3-Hydroxyflavones

inferredcites →https://doi.org/10.1021/ja062621jopenalex-snapshot

Enantioselective Photocycloaddition Mediated by Chiral Brønsted Acids: Asymmetric Synthesis of the Rocaglamides

inferredcites →https://doi.org/10.1021/ja300900popenalex-snapshot

Formal Synthesis of (±)-Methyl Rocaglate Using an Unprecedented Acetyl Bromide Mediated Nazarov Reaction

inferredcites →https://doi.org/10.1021/ja305342fopenalex-snapshot

Enantioselective Photocycloaddition of 3-Hydroxyflavones: Total Syntheses and Absolute Configuration Assignments of (+)-Ponapensin and (+)-Elliptifoline

inferredcites →https://doi.org/10.1021/ja9029736openalex-snapshot

Nazarov Cyclization Initiated by Peracid Oxidation: The Total Synthesis of (±)-Rocaglamide

inferredcites →https://doi.org/10.1021/jf990509hopenalex-snapshot

Cyclopenta[b]benzofurans from Aglaia Species with Pronounced Antifungal Activity against Rice Blast Fungus (Pyricularia grisea)

inferredcites →https://doi.org/10.1021/jm101318bopenalex-snapshot

Novel Flavaglines Displaying Improved Cytotoxicity

inferredcites →https://doi.org/10.1021/jm201263kopenalex-snapshot

Synthesis of Rocaglamide Hydroxamates and Related Compounds as Eukaryotic Translation Inhibitors: Synthetic and Biological Studies

inferredcites →https://doi.org/10.1021/jm3011542openalex-snapshot

Synthetic Silvestrol Analogues as Potent and Selective Protein Synthesis Inhibitors

inferredcites →https://doi.org/10.1021/jm301201zopenalex-snapshot

Flavaglines as Potent Anticancer and Cytoprotective Agents

inferredcites →https://doi.org/10.1021/jm900365vopenalex-snapshot

Synthetic Analogue of Rocaglaol Displays a Potent and Selective Cytotoxicity in Cancer Cells: Involvement of Apoptosis Inducing Factor and Caspase-12

inferredcites →https://doi.org/10.1021/jo040120fopenalex-snapshot

Silvestrol and Episilvestrol, Potential Anticancer Rocaglate Derivatives from Aglaia silvestris

inferredcites →https://doi.org/10.1021/jo202366copenalex-snapshot

Total Synthesis of (±)-Rocaglamide via Oxidation-Initiated Nazarov Cyclization

inferredcites →https://doi.org/10.1021/np020291kopenalex-snapshot

Cyclorocaglamide, the First Bridged Cyclopentatetrahydrobenzofuran, and a Related “Open Chain” Rocaglamide Derivative from Aglaia oligophylla

inferredcites →https://doi.org/10.1021/np0304417openalex-snapshot

Cytotoxic Constituents of the Twigs and Leaves ofAglaiarubiginosa

inferredcites →https://doi.org/10.1021/np060428xopenalex-snapshot

Cytotoxic Flavaglines and Bisamides from Aglaia edulis

inferredcites →https://doi.org/10.1021/np100503qopenalex-snapshot

Isolation and Characterization of Minor Analogues of Silvestrol and Other Constituents from a Large-Scale Re-collection of Aglaia foveolata

inferredcites →https://doi.org/10.1021/np3007588openalex-snapshot

Bioactive Flavaglines and Other Constituents Isolated from Aglaia perviridis

inferredcites →https://doi.org/10.1021/np9801965openalex-snapshot

Bisamides, Lignans, Triterpenes, and Insecticidal Cyclopenta[b]benzofurans from Aglaia Species

inferredcites →https://doi.org/10.1021/np990454dopenalex-snapshot

Flavonol−Cinnamate Cycloadducts and Diamide Derivatives from Aglaia laxiflora

inferredcites →https://doi.org/10.1021/ol400401dopenalex-snapshot

Synthesis of Biotinylated Episilvestrol: Highly Selective Targeting of the Translation Factors eIF4AI/II

inferredcites →https://doi.org/10.1038/cdd.2010.99openalex-snapshot

Rocaglamide breaks TRAIL resistance in HTLV-1-associated adult T-cell leukemia/lymphoma by translational suppression of c-FLIP expression

inferredcites →https://doi.org/10.1038/cddis.2012.149openalex-snapshot

Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor

inferredcites →https://doi.org/10.1038/nature03482openalex-snapshot

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

inferredcites →https://doi.org/10.1038/nrc2824openalex-snapshot

Translational control in cancer

inferredcites →https://doi.org/10.1038/nrclinonc.2011.16openalex-snapshot

The biological and therapeutic relevance of mRNA translation in cancer

inferredcites →https://doi.org/10.1038/nrm3083openalex-snapshot

mRNA helicases: the tacticians of translational control

inferredcites →https://doi.org/10.1038/onc.2012.236openalex-snapshot

Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein

inferredcites →https://doi.org/10.1038/sj.onc.1202684openalex-snapshot

Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function

inferredcites →https://doi.org/10.1039/c004927aopenalex-snapshot

Constituents of Amoora cucullata with TRAIL resistance-overcoming activity

inferredcites →https://doi.org/10.1039/c39820001150openalex-snapshot

X-Ray crystal structure of rocaglamide, a novel antileulemic 1H-cyclopenta[b]benzofuran from Aglaia elliptifolia

inferredcites →https://doi.org/10.1039/c39910001137openalex-snapshot

Synthesis of the novel anti-leukaemic tetrahydrocyclopenta[b]benzofuran, rocaglamide

inferredcites →https://doi.org/10.1074/jbc.m208003200openalex-snapshot

Rocaglamide Derivatives Are Potent Inhibitors of NF-κB Activation in T-cells

inferredcites →https://doi.org/10.1074/jbc.m305171200openalex-snapshot

Prohibitin Induces the Transcriptional Activity of p53 and Is Exported from the Nucleus upon Apoptotic Signaling

inferredcites →https://doi.org/10.1074/jbc.m312300200openalex-snapshot

Transcriptional Regulation by the Repressor of Estrogen Receptor Activity via Recruitment of Histone Deacetylases

inferredcites →https://doi.org/10.1111/j.1742-4658.2010.07809.xopenalex-snapshot

The role of prohibitin in cell signaling

inferredcites →https://doi.org/10.1124/mol.104.008177openalex-snapshot

A Synthetic Derivative of the Natural Product Rocaglaol Is a Potent Inhibitor of Cytokine-Mediated Signaling and Shows Neuroprotective Activity in Vitro and in Animal Models of Parkinson’s Disease and Traumatic Brain Injury

inferredcites →https://doi.org/10.1126/science.1231197openalex-snapshot

Translational Repression and eIF4A2 Activity Are Critical for MicroRNA-Mediated Gene Regulation

inferredcites →https://doi.org/10.1126/science.1238303openalex-snapshot

Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State

inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-2294openalex-snapshot

Mcl-1 Is a Relevant Therapeutic Target in Acute and Chronic Lymphoid Malignancies: Down-Regulation Enhances Rituximab-Mediated Apoptosis and Complement-Dependent Cytotoxicity

inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-0839openalex-snapshot

Dual Targeting of the Cyclin/Rb/E2F and Mitochondrial Pathways in Mantle Cell Lymphoma with the Translation Inhibitor Silvestrol

inferredcites →https://doi.org/10.1172/jci34753openalex-snapshot

Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model

inferredcites →https://doi.org/10.1182/blood-2008-09-175430openalex-snapshot

The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo

inferredcites →https://doi.org/10.1186/1756-8722-6-21openalex-snapshot

Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia

inferredcites →https://doi.org/10.1208/s12248-011-9273-xopenalex-snapshot

Characterization of Silvestrol Pharmacokinetics in Mice Using Liquid Chromatography–Tandem Mass Spectrometry

inferredcites →https://doi.org/10.1208/s12248-011-9276-7openalex-snapshot

Resistance to the Translation Initiation Inhibitor Silvestrol is Mediated by ABCB1/P-Glycoprotein Overexpression in Acute Lymphoblastic Leukemia Cells

inferredcites →https://doi.org/10.1248/cpb.54.1344openalex-snapshot

Potent Cytotoxic Rocaglamide Derivatives from the Fruits of Amoora cucullata

inferredcites →https://doi.org/10.1261/rna.033209.112openalex-snapshot

A cellular response linking eIF4AI activity to eIF4AII transcription

inferredcites →https://doi.org/10.1371/journal.pone.0005223openalex-snapshot

Antitumor Activity and Mechanism of Action of the Cyclopenta[b]benzofuran, Silvestrol

inferredcites →https://doi.org/10.1371/journal.pone.0025302openalex-snapshot

Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27

inferredcites →https://doi.org/10.1371/journal.pone.0076136openalex-snapshot

Therapeutic Potential of the Translation Inhibitor Silvestrol in Hepatocellular Cancer

inferredcites →https://doi.org/10.1515/znc-1999-1212openalex-snapshot

1H-Cyclopenta[b]benzofuran Lignans from Aglaia Species Inhibit Cell Proliferation and Alter Cell Cycle Distribution in Human Monocytic Leukemia Cell Lines

inferredcites →https://doi.org/10.1515/znc-2013-3-402openalex-snapshot

Chemical Constituents from the Leaves of Aglaia odorata

inferredcites →https://doi.org/10.1517/14728220902832697openalex-snapshot

Inhibiting the transcription factor HSF1 as an anticancer strategy

inferredcites →https://doi.org/10.2174/1385272013375049openalex-snapshot

Chemistry and Biological Activity of Rocaglamide Derivatives and Related Compounds in Aglaia Species (Meliaceae)

inferredcites →https://doi.org/10.2174/138945010791320809openalex-snapshot

Potential of Plant-Derived Natural Products in the Treatment of Leukemia and Lymphoma

inferredcites →https://doi.org/10.2174/187152006777698123openalex-snapshot

Potential of Cyclopenta[b]benzofurans from Aglaia Species in Cancer Chemotherapy

inferredcites →https://doi.org/10.4049/jimmunol.174.11.7075openalex-snapshot

Rocaglamide Derivatives Are Immunosuppressive Phytochemicals That Target NF-AT Activity in T Cells

inferredcites →https://doi.org/10.4161/cc.10.22.18288openalex-snapshot

Targeted cancer therapy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Phytochemistry and biological activities of Aglaia species

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Total Syntheses of the Isomeric Aglain Natural Products Foveoglin A and Perviridisin B: Selective Excited‐State Intramolecular Proton‐Transfer Photocycloaddition

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Regiodivergent and Enantioselective Allylic C−H Alkylation of Allyl Ethers: Optimization, Scope, Mechanism and Application

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Asymmetric Deoxygenative Difunctionalization of 1,2‐Dicarbonyl Compounds Enabled by Phosphinite and Chiral Salen‐Molybdenum Catalyst Synergy

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Synthetic flavagline derivative 1‐chloroacetylrocaglaol promotes apoptosis in K562 erythroleukemia cells through miR‐17‐92 cluster genes

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Construction of Diverse Dihydrodibenzofuranones by Migration/Intramolecular Arylation of Iodonium Ylides

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Treatment resistance analysis reveals GLUT‐1‐mediated glucose uptake as a major target of synthetic rocaglates in cancer cells

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Three New Aglain Derivatives from Aglaia odorata Lour. and Their Cytotoxic Activities

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Copper‐Catalyzed C2 and C3 Phosphonation of Benzofuran and Benzothiophene with Trialkyl Phosphites

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Evaluation of the impact of Roclaglamide on MDA-MB-231 human breast adenocarcinoma cells by cell culture and molecular approaches

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The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo

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inferred← citeshttps://doi.org/10.1021/acs.jnatprod.0c01371openalex-snapshot

Professor A. Douglas Kinghorn. A Lifetime Career Dedicated to Outstanding Service to Natural Product Sciences

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c00036openalex-snapshot

Discovery of Anticancer Agents of Diverse Natural Origin

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.3c00948openalex-snapshot

Design and Synthesis of Cytotoxic Water-Soluble Rocaglaol Derivatives against HEL Cells by Inhibiting Fli-1

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.4c01247openalex-snapshot

Additional Bioactive Silvestrol Analogs from the Roots of Aglaia perviridis Collected in Vietnam

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5b00810openalex-snapshot

Cyclopenta[b]benzofuran and Secodammarane Derivatives from the Stems of Aglaia stellatopilosa

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5c01544openalex-snapshot

Activity of Didesmethylrocaglamide in High Grade Serous Ovarian Cancer Using Preclinical In Vitro and In Vivo Models

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.9b00631openalex-snapshot

Structurally Modified Cyclopenta[b]benzofuran Analogues Isolated from Aglaia perviridis

inferred← citeshttps://doi.org/10.1021/acs.orglett.0c01944openalex-snapshot

Strategic Diastereoselective C1 Functionalization in the Aza-Rocaglamide Scaffold toward Natural Product-Inspired eIF4A Inhibitors

inferred← citeshttps://doi.org/10.1021/acs.orglett.7b02052openalex-snapshot

From Simple to Complex: Rhodium(III)-Catalyzed C–C Bond Cleavage and C–H Bond Functionalization for the Synthesis of 3a,8b-Dihydro-1H-cyclopenta[b]benzofuran-1-ones

inferred← citeshttps://doi.org/10.1021/acs.orglett.8b03786openalex-snapshot

Organocatalyzed Dearomative Cycloaddition of 2-Nitrobenzofurans and Isatin-Derived Morita–Baylis–Hillman Carbonates: Highly Stereoselective Construction of Cyclopenta[b]benzofuran Scaffolds

inferred← citeshttps://doi.org/10.1021/ja511728bopenalex-snapshot

Biomimetic Kinetic Resolution: Highly Enantio- and Diastereoselective Transfer Hydrogenation of Aglain Ketones To Access Flavagline Natural Products

inferred← citeshttps://doi.org/10.1021/jacs.8b11477openalex-snapshot

Chemical Synthesis Enables Structural Reengineering of Aglaroxin C Leading to Inhibition Bias for Hepatitis C Viral Infection

inferred← citeshttps://doi.org/10.1021/jacs.9b06446openalex-snapshot

Intercepted Retro-Nazarov Reaction: Syntheses of Amidino-Rocaglate Derivatives and Their Biological Evaluation as eIF4A Inhibitors

inferred← citeshttps://doi.org/10.1038/s41375-019-0503-zopenalex-snapshot

Targeting translation initiation by synthetic rocaglates for treating MYC-driven lymphomas

inferred← citeshttps://doi.org/10.1038/s41375-021-01308-zopenalex-snapshot

Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML

inferred← citeshttps://doi.org/10.1038/s41467-021-24108-6openalex-snapshot

Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance

inferred← citeshttps://doi.org/10.1038/s41598-018-35908-0openalex-snapshot

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

inferred← citeshttps://doi.org/10.1038/s41598-022-19818-wopenalex-snapshot

In silico study on the Hepatitis E virus RNA Helicase and its inhibition by silvestrol, rocaglamide and other flavagline compounds

inferred← citeshttps://doi.org/10.1038/srep20045openalex-snapshot

Cytotoxic Rocaglate Derivatives from Leaves of Aglaia perviridis

inferred← citeshttps://doi.org/10.1039/c9np00052fopenalex-snapshot

Selective targeting of the DEAD-box RNA helicase eukaryotic initiation factor (eIF) 4A by natural products

inferred← citeshttps://doi.org/10.1039/c9ob00775jopenalex-snapshot

Phosphine-catalyzed dearomative (3 + 2) annulation of 2-nitrobenzofurans and nitrobenzothiophenes with allenoates

inferred← citeshttps://doi.org/10.1039/d0np00024hopenalex-snapshot

Rocaglamide and silvestrol: a long story from anti-tumor to anti-coronavirus compounds

inferred← citeshttps://doi.org/10.1039/d1np00077bopenalex-snapshot

Recent advances in the synthesis of natural products containing the phloroglucinol motif

inferred← citeshttps://doi.org/10.1039/d2cc06324gopenalex-snapshot

Construction of cyclopenta[ b ]dihydronaphthofurans via TsOH-catalyzed consecutive biscyclization of dithioallylic alcohols and 1-styrylnaphthols

inferred← citeshttps://doi.org/10.1039/d2np00080fopenalex-snapshot

Strategies for the discovery of potential anticancer agents from plants collected from Southeast Asian tropical rainforests as a case study

inferred← citeshttps://doi.org/10.1039/d3md00121kopenalex-snapshot

Medicinal chemistry approaches to target the MNK–eIF4E axis in cancer

inferred← citeshttps://doi.org/10.1055/a-1401-9562openalex-snapshot

Update on Phytochemical and Biological Studies on Rocaglate Derivatives from Aglaia Species

inferred← citeshttps://doi.org/10.1070/rcr4679openalex-snapshot

ortho-Quinone methides as key intermediates in cascade heterocyclizations

inferred← citeshttps://doi.org/10.1073/pnas.1713000115openalex-snapshot

Rocaglates as dual-targeting agents for experimental cerebral malaria

inferred← citeshttps://doi.org/10.1080/14786419.2015.1016940openalex-snapshot

Cytotoxicity and Synergistic Effect of the Constituents from Roots ofAglaia odorata(Meliaceae)

inferred← citeshttps://doi.org/10.1093/nar/gkaa662openalex-snapshot

Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5′ leader regions

inferred← citeshttps://doi.org/10.1093/nar/gkae824openalex-snapshot

Protein–RNA interactions mediated by silvestrol—insight into a unique molecular clamp

inferred← citeshttps://doi.org/10.1093/narcan/zcae009openalex-snapshot

METTL3 as a master regulator of translation in cancer: mechanisms and implications

inferred← citeshttps://doi.org/10.1093/neuonc/now032openalex-snapshot

Components of the eIF4F complex are potential therapeutic targets for malignant peripheral nerve sheath tumors and vestibular schwannomas

inferred← citeshttps://doi.org/10.1101/2021.05.26.445185openalex-snapshot

Single-Molecule Dynamics of SARS-CoV-2 5’ Cap Recognition by Human eIF4F

inferred← citeshttps://doi.org/10.1155/2022/2048095openalex-snapshot

[Retracted] Rocaglamide Prolonged Allograft Survival by Inhibiting Differentiation of Th1/Th17 Cells in Cardiac Transplantation

inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-14-2362openalex-snapshot

Molecular Pathways: The eIF4F Translation Initiation Complex—New Opportunities for Cancer Treatment

inferred← citeshttps://doi.org/10.1158/1535-7163.mct-19-0809openalex-snapshot

Targeting Protein Translation by Rocaglamide and Didesmethylrocaglamide to Treat MPNST and Other Sarcomas

inferred← citeshttps://doi.org/10.1172/jci.insight.127098openalex-snapshot

Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms’ tumor

inferred← citeshttps://doi.org/10.1186/s12885-015-1988-0openalex-snapshot

Silvestrol induces early autophagy and apoptosis in human melanoma cells

inferred← citeshttps://doi.org/10.1186/s12943-023-01900-0openalex-snapshot

Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors

inferred← citeshttps://doi.org/10.1248/cpb.c16-00868openalex-snapshot

Aglaiabbrevins A–D, New Prenylated Bibenzyls from the Leaves of Aglaia abbreviata with Potent PTP1B Inhibitory Activity

inferred← citeshttps://doi.org/10.1360/ssc-2025-0149openalex-snapshot

Progress in the study of non-limonoid natural products of the Meliaceae family

inferred← citeshttps://doi.org/10.1371/journal.pone.0119028openalex-snapshot

Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity

inferred← citeshttps://doi.org/10.1371/journal.ppat.1006778openalex-snapshot

Prohibitin plays a critical role in Enterovirus 71 neuropathogenesis

inferred← citeshttps://doi.org/10.1371/journal.ppat.1006892openalex-snapshot

Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses

inferred← citeshttps://doi.org/10.21203/rs.3.rs-2816652/v1openalex-snapshot

Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors

inferred← citeshttps://doi.org/10.2174/1570179417999201228214930openalex-snapshot

Recent Advances in Metal-Catalyzed Heterocyclic C-P Bond Formation

inferred← citeshttps://doi.org/10.2174/2666001601666211126091737openalex-snapshot

Flavaglines: Their Discovery from Plants Used in Traditional Chinese Medicine, Synthesis, and Drug Development Against Cancer and Immune Disorders

inferred← citeshttps://doi.org/10.21873/anticanres.11146openalex-snapshot

Discovery of Anticancer Agents of Diverse Natural Origin

inferred← citeshttps://doi.org/10.22146/ijc.64502openalex-snapshot

Phytochemistry and Pharmacology of Munronia Genus (Meliaceae)

inferred← citeshttps://doi.org/10.22146/ijc.83694openalex-snapshot

Cytotoxic Dammarane-Type Triterpenoids from Aglaia cucullata Peel Fruit

inferred← citeshttps://doi.org/10.2217/fvl-2017-0023openalex-snapshot

Silvestrol: A Potential Future Drug for Acute Ebola and Other Viral Infections

inferred← citeshttps://doi.org/10.25135/rnp.395.2304.2756openalex-snapshot

NO Inhibitory, Farnesoid X Receptor, and Cytotoxic Activities of Phytochemical Composition Isolated from Aglaia perviridis

inferred← citeshttps://doi.org/10.2991/978-94-6463-112-8_32openalex-snapshot

Antioxidant, Antibacterial and Antibiofilm Activities of an Endophytic Fungi, Penicillium Sp. SAF6-EGY Strain AFL.2 and Arthrinium Sp. R22-1 Strain AFL.3 Isolated from Aglaia Foveolata

inferred← citeshttps://doi.org/10.3389/fchem.2020.00276openalex-snapshot

Transcription and Translation Inhibitors in Cancer Treatment

inferred← citeshttps://doi.org/10.3389/fgene.2021.714228openalex-snapshot

Role of Prohibitins in Aging and Therapeutic Potential Against Age-Related Diseases

inferred← citeshttps://doi.org/10.3389/fimmu.2024.1343316openalex-snapshot

A review of natural products targeting tumor immune microenvironments for the treatment of lung cancer

inferred← citeshttps://doi.org/10.3389/fonc.2021.698192openalex-snapshot

Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments

inferred← citeshttps://doi.org/10.3390/ijms24032055openalex-snapshot

eIF4A1 Is a Prognostic Marker and Actionable Target in Human Hepatocellular Carcinoma

inferred← citeshttps://doi.org/10.3390/jof7030159openalex-snapshot

Tools for Assessing Translation in Cryptococcus neoformans

inferred← citeshttps://doi.org/10.3390/molecules27185890openalex-snapshot

Enzymatic and Molecular Characterization of Anti-Leishmania Molecules That Differently Target Leishmania and Mammalian eIF4A Proteins, LieIF4A and eIF4AMus

inferred← citeshttps://doi.org/10.3390/su151813565openalex-snapshot

Cytotoxic Evaluation and Elucidation of Dammarane-Type Triterpenoids Isolated from the Exocarp of Aglaia cucullata (Meliaceae)

inferred← citeshttps://doi.org/10.3390/v10060301openalex-snapshot

Inhibition of Hepatitis E Virus Spread by the Natural Compound Silvestrol

inferred← citeshttps://doi.org/10.3390/v10110592openalex-snapshot

Silvestrol Inhibits Chikungunya Virus Replication

inferred← citeshttps://doi.org/10.3390/v10110601openalex-snapshot

The Natural Compound Homoharringtonine Presents Broad Antiviral Activity In Vitro and In Vivo

inferred← citeshttps://doi.org/10.3390/v11060485openalex-snapshot

Hepatitis E Virus Drug Development

inferred← citeshttps://doi.org/10.3390/v15051100openalex-snapshot

Broad-Spectrum Antivirals Derived from Natural Products

inferred← citeshttps://doi.org/10.33936/rev_bas_de_la_ciencia.v6i2.2814openalex-snapshot

El silvestrol como agente antiviral de amplio espectro

inferred← citeshttps://doi.org/10.3892/etm.2016.3201openalex-snapshot

Inhibition of nasopharyngeal carcinoma cell proliferation and synergism of cisplatin with silvestrol and episilvestrol isolated from Aglaia stellatopilosa

inferred← citeshttps://doi.org/10.3892/mco.2025.2890openalex-snapshot

Silvestrol inhibits nasopharyngeal carcinoma cells and synergizes with CX‑5461: Insights from a proteomics study

inferred← citeshttps://doi.org/10.4018/978-1-7998-8225-1.ch015openalex-snapshot

Herbal Products for Management of COVID- 19

inferred← citeshttps://doi.org/10.4103/ijmr.ijmr_585_20openalex-snapshot

Perspectives for repurposing drugs for the coronavirus disease 2019

inferred← citeshttps://doi.org/10.54844/cai.2022.0079openalex-snapshot

Promoting development of tertiary hospital by satisfaction surveys

inferred← citeshttps://doi.org/10.6084/m9.figshare.24844640openalex-snapshot

Additional file 1 of Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors

inferred← citeshttps://doi.org/10.70675/187424b5z872bz46bcz9e90za49cf5fb8269openalex-snapshot

Pre-mRNA 3'-end polyadenylation : impact on UV-induced DNA damage and on the translatability of immune-related genes

inferred← citeshttps://doi.org/10.70675/7c36bc77zbcf8z4d6ez988dzdd814ec9a952openalex-snapshot

Role of the immune receptor CD47 in mouse model of non-infectious uveitis

inferred← citeshttps://doi.org/10.70675/7d68b550za64ez450ez9652z105c70164939openalex-snapshot

Development of new approaches for the synthesis of flavaglines

inferred← citeshttps://doi.org/10.70675/907b71d5z497ez45c1za40azfb52b263aeb7openalex-snapshot

Etude de l’implication du complexe eIF4F dans la réponse immune antitumorale via la régulation traductionnelle de l’axe STAT1-PD-L1 dans le mélanome métastatique

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