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Antitrypanosomal and antileishmanial activity of prenyl-1,2,3-triazoles
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes
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Cytochrome P450 and the Individuality of Species
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Sterol 14-Demethylase P450 (CYP51) Provides a Breakthrough for the Discussion on the Evolution of Cytochrome P450 Gene Superfamily
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A click chemistry strategy to synthesize geraniol-coupled 1,4-disubstituted 1,2,3-triazoles and exploration of their microbicidal and antioxidant potential with molecular docking profile
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Geranyl and neryl triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase
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Targeting bacterial biofilms: Design of a terpenoid-like library as non-toxic anti-biofilm compounds
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Triazole-based inhibitors of geranylgeranyltransferase II
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Synthesis of glycotriazololipids and observations on their self-assembly properties
inferredcites →https://doi.org/10.1016/j.chembiol.2007.10.011openalex-snapshot
Sterol 14α-Demethylase as a Potential Target for Antitrypanosomal Therapy: Enzyme Inhibition and Parasite Cell Growth
inferredcites →https://doi.org/10.1016/j.steroids.2013.10.010openalex-snapshot
Click chemistry decoration of amino sterols as promising strategy to developed new leishmanicidal drugs
inferredcites →https://doi.org/10.1016/j.tetlet.2009.01.125openalex-snapshot
Synthesis of a polyprenyl-type library containing 1,4-disubstituted-1,2,3-triazoles with anti-biofilm activities against Pseudoalteromonas sp.
inferredcites →https://doi.org/10.1016/s0169-409x(00)00129-0openalex-snapshot
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
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Screening strategies to identify new chemical diversity for drug development to treat kinetoplastid infections
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Potent Triazole Bisphosphonate Inhibitor of Geranylgeranyl Diphosphate Synthase
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The Allylic Azide Rearrangement: Achieving Selectivity
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Direct conversion of activated alcohols to azides using diphenyl phosphorazidate. A practical alternative to Mitsunobu conditions
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Studies on the Preparation and Rearrangements of Allylic Azides1
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Farnesyl Diphosphate Analogues with ω-Bioorthogonal Azide and Alkyne Functional Groups for Protein Farnesyl Transferase-Catalyzed Ligation Reactions
inferredcites →https://doi.org/10.1038/nrd4683openalex-snapshot
Hit and lead criteria in drug discovery for infectious diseases of the developing world
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Click-based synthesis and proteomic profiling of lipstatin analogues
inferredcites →https://doi.org/10.1039/c3md00388dopenalex-snapshot
α-Aminophosphonates as novel anti-leishmanial chemotypes: synthesis, biological evaluation, and CoMFA studies
inferredcites →https://doi.org/10.1055/s-0031-1290461openalex-snapshot
Synthesis of Farnesol Analogues Containing Triazoles in Place of Isoprenes through ‘Click Chemistry’
inferredcites →https://doi.org/10.1056/nejmoa1507574openalex-snapshot
Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy
inferredcites →https://doi.org/10.1074/jbc.m111.237099openalex-snapshot
Substrate Preferences and Catalytic Parameters Determined by Structural Characteristics of Sterol 14α-Demethylase (CYP51) from Leishmania infantum
inferredcites →https://doi.org/10.1074/jbc.m113.497990openalex-snapshot
Complexes of Trypanosoma cruzi Sterol 14α-Demethylase (CYP51) with Two Pyridine-based Drug Candidates for Chagas Disease
inferredcites →https://doi.org/10.1155/2009/642502openalex-snapshot
Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs
inferredcites →https://doi.org/10.1194/jlr.m021865openalex-snapshot
Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Δ7-24, 25-dihydrolanosterol
inferredcites →https://doi.org/10.1371/journal.pntd.0003219openalex-snapshot
Chagas Disease and the London Declaration on Neglected Tropical Diseases
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Recent Developments in Rationally Designed Multitarget Antiprotozoan Agents
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Macrocycles as Potential Therapeutic Agents in Neglected Diseases
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1002/tcr.202000185openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s11030-019-09953-4openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.105250openalex-snapshot
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Lipophilic modification of salirasib modulates the antiproliferative and antimigratory activity
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Systematic study of 1,2,3-triazolyl sterols for the development of new drugs against parasitic Neglected Tropical Diseases
inferred← citeshttps://doi.org/10.1021/acs.joc.9b02443openalex-snapshot
Metal-Free Route to Carboxylated 1,4-Disubstituted 1,2,3-Triazoles from Methoxycarbonyl-Modified Vinyl Sulfone
inferred← citeshttps://doi.org/10.1039/c7ra09759jopenalex-snapshot
Experimental and theoretical studies of the [3,3]-sigmatropic rearrangement of prenyl azides
inferred← citeshttps://doi.org/10.1039/c9md00298gopenalex-snapshot
Repositioning Salirasib as a new antimalarial agent
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Expanding the scope of novel 1,2,3-triazole derivatives as new antiparasitic drug candidates
inferred← citeshttps://doi.org/10.1080/00397911.2018.1544371openalex-snapshot
One-pot facile synthesis, crystal structure and antifungal activity of 1,2,3-triazoles bridged with amine-amide functionalities
inferred← citeshttps://doi.org/10.1080/00397911.2020.1802758openalex-snapshot
Synthesis, characterization and biological activities of sulfonamide tagged 1,2,3-triazoles
inferred← citeshttps://doi.org/10.1111/cbdd.13628openalex-snapshot
Synthesis, activity, and molecular modeling studies of 1,2,3‐triazole derivatives from natural phenylpropanoids as new trypanocidal agents
inferred← citeshttps://doi.org/10.21203/rs.3.rs-10624493/v1openalex-snapshot
In vitro and In Silico Investigation of Antileishmanial Activity of 1,2,3-Triazole Tethered 2,3-Dihydroquinazolin-4-[1H]-one Conjugates Against L. Infantum
inferred← citeshttps://doi.org/10.26434/chemrxiv-2021-l64kgopenalex-snapshot
Proline transport inhibitors trigger differential responses in Trypanosoma cruzi growth inhibition
inferred← citeshttps://doi.org/10.26434/chemrxiv.7564991.v1openalex-snapshot
Rationally Design of a Proline Transporter Inhibitor with Anti-Trypanosoma Cruzi Activity
inferred← citeshttps://doi.org/10.33774/chemrxiv-2021-q0q9vopenalex-snapshot
Systematic study of triazolyl sterols for the development of new drugs against parasitic Neglected Tropical Diseases.
inferred← citeshttps://doi.org/10.3389/fchbi.2026.1848258openalex-snapshot
Unravelling the effects of proline analogues against Trypanosoma cruzi
inferred← citeshttps://doi.org/10.3389/fchem.2020.00696openalex-snapshot
Targeting L-Proline Uptake as New Strategy for Anti-chagas Drug Development
inferred← citeshttps://doi.org/10.3390/tropicalmed10050142openalex-snapshot
Progress and Prospects of Triazoles in Advanced Therapies for Parasitic Diseases
inferred← citeshttps://doi.org/10.4155/fmc-2021-0354openalex-snapshot
Design, Synthesis and Evaluation of Novel Phenanthridine Triazole Analogs as Potential Antileishmanial Agents
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