On the public citation graph

The expanding spectrum of diketopiperazine natural product biosynthetic pathways containing cyclodipeptide synthases

0 signed · 197 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.201710529openalex-snapshot

A Six‐Oxidase Cascade for Tandem C−H Bond Activation Revealed by Reconstitution of Bicyclomycin Biosynthesis

inferredcites →https://doi.org/10.1002/anie.201712536openalex-snapshot

Incorporation of Non‐canonical Amino Acids into 2,5‐Diketopiperazines by Cyclodipeptide Synthases

inferredcites →https://doi.org/10.1002/cbdv.200790240openalex-snapshot

Three Novel, Structurally Unique Spirocyclic Alkaloids from the Halotolerant B‐17 Fungal Strain of Aspergillus variecolor

inferredcites →https://doi.org/10.1002/prot.24474openalex-snapshot

QM/MM study of the C—C coupling reaction mechanism of CYP121, an essential Cytochrome p450 of Mycobacterium tuberculosis

inferredcites →https://doi.org/10.1007/s00253-013-5175-4openalex-snapshot

Tentative biosynthetic pathways of some microbial diketopiperazines

inferredcites →https://doi.org/10.1007/s00253-018-8908-6openalex-snapshot

Expanding tryptophan-containing cyclodipeptide synthase spectrum by identification of nine members from Streptomyces strains

inferredcites →https://doi.org/10.1016/j.cbpa.2016.08.018openalex-snapshot

Cameo appearances of aminoacyl-tRNA in natural product biosynthesis

inferredcites →https://doi.org/10.1016/j.chembiol.2011.09.010openalex-snapshot

Nonribosomal Peptide Synthesis in Animals: The Cyclodipeptide Synthase of Nematostella

inferredcites →https://doi.org/10.1016/j.chembiol.2013.04.017openalex-snapshot

Insights into the Generation of Structural Diversity in a tRNA-Dependent Pathway for Highly Modified Bioactive Cyclic Dipeptides

inferredcites →https://doi.org/10.1016/j.chembiol.2015.02.005openalex-snapshot

Biosynthetic Manipulation of Tryptophan in Bacteria: Pathways and Mechanisms

inferredcites →https://doi.org/10.1016/j.febslet.2012.01.017openalex-snapshot

Ribosome‐independent biosynthesis of biologically active peptides: Application of synthetic biology to generate structural diversity

inferredcites →https://doi.org/10.1016/j.jsb.2018.03.001openalex-snapshot

Structural basis for partition of the cyclodipeptide synthases into two subfamilies

inferredcites →https://doi.org/10.1016/j.sbi.2016.05.009openalex-snapshot

Structure and mechanism of assembly line polyketide synthases

inferredcites →https://doi.org/10.1016/s0960-894x(97)10104-4openalex-snapshot

(−)-Phenylahistin: A new mammalian cell cycle inhibitor produced by aspergillus ustus

inferredcites →https://doi.org/10.1016/s1074-5521(02)00285-5openalex-snapshot

The Albonoursin Gene Cluster of S. noursei

inferredcites →https://doi.org/10.1021/acs.biochem.7b00943openalex-snapshot

Identification of the Biosynthetic Pathway for the Antibiotic Bicyclomycin

inferredcites →https://doi.org/10.1021/acs.chemrev.6b00523openalex-snapshot

Aminoacyl-tRNA-Utilizing Enzymes in Natural Product Biosynthesis

inferredcites →https://doi.org/10.1021/acs.jmedchem.6b00007openalex-snapshot

Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors

inferredcites →https://doi.org/10.1021/acs.jnatprod.5b01055openalex-snapshot

Natural Products as Sources of New Drugs from 1981 to 2014

inferredcites →https://doi.org/10.1021/acs.jnatprod.7b00430openalex-snapshot

Mutations of Residues in Pocket P1 of a Cyclodipeptide Synthase Strongly Increase Product Formation

inferredcites →https://doi.org/10.1021/acs.orglett.8b02051openalex-snapshot

Coupling of Guanine with cyclo- l -Trp- l -Trp Mediated by a Cytochrome P450 Homologue from Streptomyces purpureus

inferredcites →https://doi.org/10.1021/acssynbio.5b00120openalex-snapshot

Two Distinct Cyclodipeptide Synthases from a Marine Actinomycete Catalyze Biosynthesis of the Same Diketopiperazine Natural Product

inferredcites →https://doi.org/10.1021/bi00065a007openalex-snapshot

Transcription termination factor rho: The site of bicyclomycin inhibition in Escherichia coli

inferredcites →https://doi.org/10.1021/bi100910yopenalex-snapshot

Structural and Biochemical Characterization of the Cytochrome P450 CypX (CYP134A1) from Bacillus subtilis : A Cyclo- l -leucyl- l -leucyl Dipeptide Oxidase

inferredcites →https://doi.org/10.1021/bi4004827openalex-snapshot

A tRNA-Dependent Two-Enzyme Pathway for the Generation of Singly and Doubly Methylated Ditryptophan 2,5-Diketopiperazines

inferredcites →https://doi.org/10.1021/cb100105copenalex-snapshot

Natural Products as Chemical Probes

inferredcites →https://doi.org/10.1021/cr200398yopenalex-snapshot

2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products

inferredcites →https://doi.org/10.1021/ja909118aopenalex-snapshot

Natural Products Version 2.0: Connecting Genes to Molecules

inferredcites →https://doi.org/10.1021/jf00017a025openalex-snapshot

Chemistry of phytotoxins associated with Streptomyces scabies the causal organism of potato common scab

inferredcites →https://doi.org/10.1021/jo050963mopenalex-snapshot

Joys of Molecules. 1. Campaigns in Total Synthesis

inferredcites →https://doi.org/10.1021/np100754jopenalex-snapshot

Natural Products as Molecular Messengers

inferredcites →https://doi.org/10.1021/np200597mopenalex-snapshot

α-Pyrones and Diketopiperazine Derivatives from the Marine-Derived Actinomycete Nocardiopsis dassonvillei HR10-5

inferredcites →https://doi.org/10.1021/ol200904vopenalex-snapshot

Nocardioazines: A Novel Bridged Diketopiperazine Scaffold from a Marine-Derived Bacterium Inhibits P-Glycoprotein

inferredcites →https://doi.org/10.1021/ol901466ropenalex-snapshot

Naseseazines A and B: A New Dimeric Diketopiperazine Framework from a Marine-Derived Actinomycete, Streptomyces sp.

inferredcites →https://doi.org/10.1038/ja.2012.88openalex-snapshot

New diketopiperazine derivatives from a deep-sea-derived Nocardiopsis alba SCSIO 03039

inferredcites →https://doi.org/10.1038/nbt1266openalex-snapshot

New antibiotics from bacterial natural products

inferredcites →https://doi.org/10.1038/nchembio.175openalex-snapshot

Cyclodipeptide synthases are a family of tRNA-dependent peptide bond–forming enzymes

inferredcites →https://doi.org/10.1038/nchembio.1868openalex-snapshot

Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity

inferredcites →https://doi.org/10.1038/nchembio.440openalex-snapshot

The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase

inferredcites →https://doi.org/10.1038/ncomms6141openalex-snapshot

Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases

inferredcites →https://doi.org/10.1038/s41467-017-02088-wopenalex-snapshot

Structural absorption by barbule microstructures of super black bird of paradise feathers

inferredcites →https://doi.org/10.1038/s41467-018-06411-xopenalex-snapshot

Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery

inferredcites →https://doi.org/10.1038/s41467-018-06528-zopenalex-snapshot

Efficient biosynthesis of heterodimeric C3-aryl pyrroloindoline alkaloids

inferredcites →https://doi.org/10.1038/s41467-018-07548-5openalex-snapshot

Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge

inferredcites →https://doi.org/10.1039/c2np20029eopenalex-snapshot

Architectures, mechanisms and molecular evolution of natural product methyltransferases

inferredcites →https://doi.org/10.1039/c4np00060aopenalex-snapshot

Fungal natural products in research and development

inferredcites →https://doi.org/10.1039/c4np00099dopenalex-snapshot

Mechanistic studies on the indole prenyltransferases

inferredcites →https://doi.org/10.1039/c4np00120fopenalex-snapshot

Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis

inferredcites →https://doi.org/10.1039/c4np00166dopenalex-snapshot

Chemical ecology of fungi

inferredcites →https://doi.org/10.1039/c5np00013kopenalex-snapshot

Natural products in soil microbe interactions and evolution

inferredcites →https://doi.org/10.1039/c5ob00537jopenalex-snapshot

Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis

inferredcites →https://doi.org/10.1039/c6mb00675bopenalex-snapshot

Diversity of nature's assembly lines – recent discoveries in non-ribosomal peptide synthesis

inferredcites →https://doi.org/10.1039/c7np00052aopenalex-snapshot

Marine natural products

inferredcites →https://doi.org/10.1046/j.1432-1327.2001.02038.xopenalex-snapshot

Cyclic dipeptide oxidase from Streptomyces noursei

inferredcites →https://doi.org/10.1073/pnas.0812191106openalex-snapshot

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

inferredcites →https://doi.org/10.1073/pnas.1019480108openalex-snapshot

Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog

inferredcites →https://doi.org/10.1073/pnas.1806268115openalex-snapshot

Functional and evolutionary characterization of a secondary metabolite gene cluster in budding yeasts

inferredcites →https://doi.org/10.1073/pnas.39.7.583openalex-snapshot

Pulcherrimin, The Pigment of Candida Pulcherrima

inferredcites →https://doi.org/10.1074/jbc.m112.443853openalex-snapshot

Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121

inferredcites →https://doi.org/10.1074/jbc.m117.794099openalex-snapshot

Cross-linking of dicyclotyrosine by the cytochrome P450 enzyme CYP121 from Mycobacterium tuberculosis proceeds through a catalytic shunt pathway

inferredcites →https://doi.org/10.1074/jbc.m802115200openalex-snapshot

Characterization of Active Site Structure in CYP121: A Cytochrome P450 Essential for Viability of Mycobacterium Tuberculosis H37Rv*

inferredcites →https://doi.org/10.1080/10575639908048788openalex-snapshot

New Cytotoxic Epidithiodioxopiperazines Related to Verticillin A From A Marine Isolate of the FungusPenicillium

inferredcites →https://doi.org/10.1089/ind.2006.2.66openalex-snapshot

Use of transcriptional profiling & bioinformatics to solve production problems: Eliminating red pigment production in a Bacillus subtilis strain producing hyaluronic acid

inferredcites →https://doi.org/10.1093/nar/gkr027openalex-snapshot

Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis

inferredcites →https://doi.org/10.1093/nar/gku348openalex-snapshot

Specificity determinants for the two tRNA substrates of the cyclodipeptide synthase AlbC from Streptomyces noursei

inferredcites →https://doi.org/10.1126/science.1170777openalex-snapshot

Total Synthesis of (+)-11,11'-Dideoxyverticillin A

inferredcites →https://doi.org/10.1128/aem.02828-17openalex-snapshot

Discovery and Biosynthesis of the Antibiotic Bicyclomycin in Distantly Related Bacterial Classes

inferredcites →https://doi.org/10.1128/jb.111.1.86-93.1972openalex-snapshot

Synthesis of Pulcherriminic Acid by Bacillus subtilis

inferredcites →https://doi.org/10.1186/s12864-018-4435-1openalex-snapshot

Global analysis of prokaryotic tRNA-derived cyclodipeptide biosynthesis

inferredcites →https://doi.org/10.1186/s12864-018-4441-3openalex-snapshot

Genetical genomics of growth in a chicken model

inferredcites →https://doi.org/10.2174/092986712801323243openalex-snapshot

Antimicrobial and Biofilm Inhibiting Diketopiperazines

inferredcites →https://doi.org/10.2210/pdb6ez3/pdbopenalex-snapshot

Structure of CDPS from Staphylococcus haemolyticus

inferredcites →https://doi.org/10.3389/fmicb.2018.00046openalex-snapshot

A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes

inferredcites →https://doi.org/10.3390/ijms150814610openalex-snapshot

The tRNA-Dependent Biosynthesis of Modified Cyclic Dipeptides

inferredcites →https://doi.org/10.3390/molecules22101796openalex-snapshot

Cyclodipeptides: An Overview of Their Biosynthesis and Biological Activity

inferredcites →https://doi.org/10.7164/antibiotics.25.576openalex-snapshot

BICYCLOMYCIN, A NEW ANTIBIOTIC

inferredcites →https://doi.org/10.7164/antibiotics.26.175openalex-snapshot

BIOLOGICAL ACTIVITIES OF ALBONOURSIN

inferredcites →https://doi.org/10.7164/antibiotics.33.488openalex-snapshot

Biosynthesis of bicyclomycin. II. Biosynthetic conditions and incorporation of radioactive precursors into bicyclomycin by washed mycelium.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113140zenodo-depositor-declared

Two pairs of undescribed enantiomers isolated from the fungus Penicillium griseofulvum

inferred← citeshttps://doi.org/10.1002/9783527834204.ch5openalex-snapshot

Diketopiperazines as Chiral Building Blocks

inferred← citeshttps://doi.org/10.1002/adsc.202000470openalex-snapshot

Synthesis of Diketopiperazine Scaffolds with Tailored N‐ and α‐Chains by Selective Modification of Customizable Units

inferred← citeshttps://doi.org/10.1002/adsc.202100658openalex-snapshot

Synthesis of Indoline‐Fused 2,5‐Diketopiperazine Scaffolds via Ugi‐4CR in the Basic Mediated Tandem Consecutive Cyclization

inferred← citeshttps://doi.org/10.1002/ajoc.202300177openalex-snapshot

Catalytic Asymmetric Syntheses of 2,5‐Diketopiperazine (DKP) Frameworks

inferred← citeshttps://doi.org/10.1002/ajoc.70395openalex-snapshot

Prebiotic Organic Chemistry of Diketopiperazines

inferred← citeshttps://doi.org/10.1002/ange.201906891openalex-snapshot

Guanitrypmycin Biosynthetic Pathways Imply Cytochrome P450 Mediated Regio‐ and Stereospecific Guaninyl‐Transfer Reactions

inferred← citeshttps://doi.org/10.1002/ange.202200377openalex-snapshot

Weit verbreitete bifunktionelle, bakterielle Cytochrom P450 Enzyme katalysieren sowohl eine intramolekulare C−C‐Bindung in cyclo‐ l ‐Tyr‐ l ‐Tyr als auch dessen Verknüpfung mit Nukleinbasen

inferred← citeshttps://doi.org/10.1002/ange.202216989openalex-snapshot

Hydroxylation with Unusual Stereoinversion Catalyzed by an FeII/2‐OG Dependent Oxidase and 3,6‐Diene‐2,5‐diketopiperazine Formation in the Biosynthesis of Brevianamide K

inferred← citeshttps://doi.org/10.1002/ange.202313606openalex-snapshot

Creating a Defined Chirality in Amino Acids and Cyclic Dipeptides by Photochemical Deracemization

inferred← citeshttps://doi.org/10.1002/ange.202421950openalex-snapshot

Formation of the Diketopiperazine Moiety by a Distinct Condensation‐Like Domain in Hangtaimycin Biosynthesis

inferred← citeshttps://doi.org/10.1002/anie.201906891openalex-snapshot

Guanitrypmycin Biosynthetic Pathways Imply Cytochrome P450 Mediated Regio‐ and Stereospecific Guaninyl‐Transfer Reactions

inferred← citeshttps://doi.org/10.1002/anie.202200377openalex-snapshot

Widely Distributed Bifunctional Bacterial Cytochrome P450 Enzymes Catalyze both Intramolecular C−C Bond Formation in cyclo ‐ l ‐Tyr‐ l ‐Tyr and Its Coupling with Nucleobases

inferred← citeshttps://doi.org/10.1002/anie.202216989openalex-snapshot

Hydroxylation with Unusual Stereoinversion Catalyzed by an FeII/2‐OG Dependent Oxidase and 3,6‐Diene‐2,5‐diketopiperazine Formation in the Biosynthesis of Brevianamide K

inferred← citeshttps://doi.org/10.1002/anie.202313606openalex-snapshot

Creating a Defined Chirality in Amino Acids and Cyclic Dipeptides by Photochemical Deracemization

inferred← citeshttps://doi.org/10.1002/anie.202421950openalex-snapshot

Formation of the Diketopiperazine Moiety by a Distinct Condensation‐Like Domain in Hangtaimycin Biosynthesis

inferred← citeshttps://doi.org/10.1002/cbdv.202201087openalex-snapshot

Exploration of the Production of Three Thiodiketopiperazines by an Endophytic Fungal Strain of Cophinforma mamane

inferred← citeshttps://doi.org/10.1002/cbic.202200341openalex-snapshot

Epipolythiodioxopiperazine‐Based Natural Products: Building Blocks, Biosynthesis and Biological Activities

inferred← citeshttps://doi.org/10.1002/cbic.202200502openalex-snapshot

Genomics‐Guided Efficient Identification of 2,5‐Diketopiperazine Derivatives from Actinobacteria

inferred← citeshttps://doi.org/10.1002/cmdc.202100149openalex-snapshot

Cyclic Dipeptide: A Privileged Molecular Scaffold to Derive Structural Diversity and Functional Utility

inferred← citeshttps://doi.org/10.1002/slct.202201120openalex-snapshot

Iodinated Diketopiperazines: Synthesis and Biological Evaluation of Iodinated Analogues of Cyclo(L‐Tyrosine‐L‐Tyrosine) Peptides

inferred← citeshttps://doi.org/10.1007/s00248-022-02016-6openalex-snapshot

Antibiotic Activity Altered by Competitive Interactions Between Two Coral Reef–Associated Bacteria

inferred← citeshttps://doi.org/10.1007/s00253-020-10392-7openalex-snapshot

Comparative studies on similarities and differences of cyclodipeptide oxidases for installation of C–C double bonds at the diketopiperazine ring

inferred← citeshttps://doi.org/10.1007/s00253-021-11178-1openalex-snapshot

Modifications of diketopiperazines assembled by cyclodipeptide synthases with cytochrome P450 enzymes

inferred← citeshttps://doi.org/10.1007/s00253-022-12004-yopenalex-snapshot

One-pot synthesis of 2,5-diketopiperazine with high titer and versatility using adenylation enzyme

inferred← citeshttps://doi.org/10.1007/s00253-024-13026-4openalex-snapshot

Novel anti-inflammatory diketopiperazine alkaloids from the marine-derived fungus Penicillium brasilianum

inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14712-2openalex-snapshot

Enzyme Evolution in Secondary Metabolism

inferred← citeshttps://doi.org/10.1016/b978-0-323-91253-2.00006-6openalex-snapshot

Extraction, isolation, and Biological activity of natural cyclic dipeptides

inferred← citeshttps://doi.org/10.1016/b978-0-443-34055-0.00007-2openalex-snapshot

Plant growth promotion by bacterial cyclodipeptides: novel insights into TOR/S6K pathway activation

inferred← citeshttps://doi.org/10.1016/bs.aihch.2021.09.002openalex-snapshot

The literature of heterocyclic chemistry, Part XIX, 2019

inferred← citeshttps://doi.org/10.1016/bs.alkal.2023.06.002openalex-snapshot

Total synthesis of complex 2,5-diketopiperazine alkaloids

inferred← citeshttps://doi.org/10.1016/j.biortech.2025.132218openalex-snapshot

Global analysis of fungal biosynthetic gene clusters reveals the diversification of diketopiperazine biosynthesis

inferred← citeshttps://doi.org/10.1016/j.bmc.2023.117372openalex-snapshot

Cyclic dipeptides and the human microbiome: Opportunities and challenges

inferred← citeshttps://doi.org/10.1016/j.cbpa.2020.09.006openalex-snapshot

Synthetic biology for natural product drug production and engineering

inferred← citeshttps://doi.org/10.1016/j.cej.2019.123493openalex-snapshot

Lysine-cyclodipeptide-based polyamidoamine microparticles: Balance between the efficiency of copper ion removal and degradation in water

inferred← citeshttps://doi.org/10.1016/j.cej.2025.160259openalex-snapshot

Quorum sensing inhibitory of plant extracts on specific spoilage organisms and the potential utilization on the preservation of aquatic products

inferred← citeshttps://doi.org/10.1016/j.chempr.2024.07.026openalex-snapshot

Ribosomal peptides with polycyclic isoprenoid moieties

inferred← citeshttps://doi.org/10.1016/j.copbio.2026.103476openalex-snapshot

Cytochrome P450-mediated structural diversification of diketopiperazine alkaloids

inferred← citeshttps://doi.org/10.1016/j.engmic.2022.100067openalex-snapshot

Natural and engineered cyclodipeptides: Biosynthesis, chemical diversity, and engineering strategies for diversification and high-yield bioproduction.

inferred← citeshttps://doi.org/10.1016/j.fitote.2026.107441openalex-snapshot

Aspergillus-derived indole diketopiperazines (IDKPs): chemical diversity, biosynthetic logics, and therapeutic potential

inferred← citeshttps://doi.org/10.1016/j.fochx.2024.101646openalex-snapshot

Identifying distinct markers in two Sorghum varieties for baijiu fermentation using untargeted metabolomics and molecular network approaches

inferred← citeshttps://doi.org/10.1016/j.ijfoodmicro.2021.109384openalex-snapshot

Metschnikowia citriensis FL01 antagonize Geotrichum citri-aurantii in citrus fruit through key action of iron depletion

inferred← citeshttps://doi.org/10.1016/j.isci.2020.101323openalex-snapshot

Expanding the Structural Diversity of Drimentines by Exploring the Promiscuity of Two N-methyltransferases

inferred← citeshttps://doi.org/10.1016/j.isci.2022.104556openalex-snapshot

Organic geochemistry and mineralogy suggest anthropogenic impact in speleothem chemistry from volcanic show caves of the Galapagos

inferred← citeshttps://doi.org/10.1016/j.medidd.2026.100266openalex-snapshot

From mushroom metabolome to prioritized anti-diabetic metabolite candidates: LC-MS/MS and AIDDISON™-assisted screening of Pleurotus citrinopileatus

inferred← citeshttps://doi.org/10.1016/j.pbb.2024.173842openalex-snapshot

Prospecting for para-endogenous anxiolytics in the human microbiome: Some promising pathways

inferred← citeshttps://doi.org/10.1016/j.pmpp.2024.102425openalex-snapshot

Unveiling the biocontrol potential of Streptomyces sp. OR02 against Rhizoctonia solani in Tomato fruit

inferred← citeshttps://doi.org/10.1016/j.postharvbio.2024.112933openalex-snapshot

Mechanism of the enhancement in disease resistance of citrus fruit induced by Metschnikowia citriensis treated with tryptophan

inferred← citeshttps://doi.org/10.1016/j.tet.2024.134067openalex-snapshot

Application of post-Ugi transformation strategies towards the synthesis and functionalization of 2,5-Diketopiperazines

inferred← citeshttps://doi.org/10.1016/j.ymben.2025.03.018openalex-snapshot

BGC heteroexpression strategy for production of novel microbial secondary metabolites

inferred← citeshttps://doi.org/10.1021/acs.biochem.4c00505openalex-snapshot

Crystal Structure and Mutagenesis of an XYP Subfamily Cyclodipeptide Synthase Reveal Key Determinants of Enzyme Activity and Substrate Specificity

inferred← citeshttps://doi.org/10.1021/acs.chemmater.4c03245openalex-snapshot

Modulable Supramolecular Hydrogels via Co-Assembly Using Cyclic Dipeptides: Influence of One Methyl Group

inferred← citeshttps://doi.org/10.1021/acs.chemrev.9b00408openalex-snapshot

Biosynthetic Pathways to Nonproteinogenic α-Amino Acids

inferred← citeshttps://doi.org/10.1021/acs.jafc.1c07790openalex-snapshot

2,5-Diketopiperazines via Intramolecular N-Alkylation of Ugi Adducts: A Contribution to the Synthesis, Density Functional Theory Study, X-ray Characterization, and Potential Herbicide Application

inferred← citeshttps://doi.org/10.1021/acs.jafc.4c08573openalex-snapshot

NRPS-like Gene LYS2 Contributed to the Biosynthesis of Cyclo(Pro-Val) in a Multistress-Tolerant Aromatic Probiotic, Meyerozyma guilliermondii GXDK6

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.1c00457openalex-snapshot

Indole Alkaloids from a Soil-Derived Clonostachys rosea

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c00787openalex-snapshot

A Streptomyces Cytochrome P450 Enzyme Catalyzes Regiospecific C2-Guaninylation for the Synthesis of Diverse Guanitrypmycin Analogs

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.9b00429openalex-snapshot

Photopiperazines A–D, Photosensitive Interconverting Diketopiperazines with Significant and Selective Activity against U87 Glioblastoma Cells, from a Rare, Marine-Derived Actinomycete of the Family Streptomycetaceae

inferred← citeshttps://doi.org/10.1021/acs.orglett.1c01022openalex-snapshot

Global Genome Mining Reveals a Cytochrome P450-Catalyzed Cyclization of Crownlike Cyclodipeptides with Neuroprotective Activity

inferred← citeshttps://doi.org/10.1021/acs.orglett.9b02666openalex-snapshot

Two Cytochrome P450 Enzymes from Streptomyces sp. NRRL S-1868 Catalyze Distinct Dimerization of Tryptophan-Containing Cyclodipeptides

inferred← citeshttps://doi.org/10.1021/acs.orglett.9b03491openalex-snapshot

Coupling of cyclo- l -Trp- l -Trp with Hypoxanthine Increases the Structure Diversity of Guanitrypmycins

inferred← citeshttps://doi.org/10.1021/acscatal.1c04609openalex-snapshot

Biosynthesis of Guatrypmethine C Implies Two Different Oxidases for exo Double Bond Installation at the Diketopiperazine Ring

inferred← citeshttps://doi.org/10.1021/acscatal.5c09276openalex-snapshot

Designing an Enzyme Cascade System for N-Heterocycle Synthesis

inferred← citeshttps://doi.org/10.1021/acscatal.5c09282openalex-snapshot

Biosynthesis of Methylated Ditryptophan 2,5-Diketopeprazine Involves Cryptic N -nitrosation

inferred← citeshttps://doi.org/10.1021/acssynbio.3c00115openalex-snapshot

Production of Diketopiperazine Derivatives by Pathway Engineering with Different Cyclodipeptide Synthases from Various Streptomyces Strains

inferred← citeshttps://doi.org/10.1021/jacs.4c06734openalex-snapshot

Fragment-Guided Genome Mining of Octacyclic Cyclophane Alkaloids from Fungi

inferred← citeshttps://doi.org/10.1021/jacs.5c08627openalex-snapshot

Biosynthesis of Unnatural Cyclodipeptides through Genetic Code Expansion and Cyclodipeptide Synthase Evolution

inferred← citeshttps://doi.org/10.1038/s41467-023-38168-3openalex-snapshot

Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase

inferred← citeshttps://doi.org/10.1038/s41467-024-48030-9openalex-snapshot

Cyclodipeptide oxidase is an enzyme filament

inferred← citeshttps://doi.org/10.1038/s41467-026-69723-3openalex-snapshot

Enhancing microbial metabolic capacity through high-energy electron beam-induced intense structural variations

inferred← citeshttps://doi.org/10.1038/s41589-019-0331-5openalex-snapshot

Convergent biosynthetic transformations to a bacterial specialized metabolite

inferred← citeshttps://doi.org/10.1038/s42004-022-00715-2openalex-snapshot

Active site remodelling of a cyclodipeptide synthase redefines substrate scope

inferred← citeshttps://doi.org/10.1039/c9cc03745dopenalex-snapshot

Pyrroloindoline cyclization in tryptophan-containing cyclodipeptides mediated by an unprecedented indole C3 methyltransferase from Streptomyces sp. HPH0547

inferred← citeshttps://doi.org/10.1039/c9np00036dopenalex-snapshot

Cyclodipeptide synthases: a promising biotechnological tool for the synthesis of diverse 2,5-diketopiperazines

inferred← citeshttps://doi.org/10.1039/c9np00048hopenalex-snapshot

Evolutionary dynamics of natural product biosynthesis in bacteria

inferred← citeshttps://doi.org/10.1039/d0cc04772dopenalex-snapshot

Increasing cytochrome P450 enzyme diversity by identification of two distinct cyclodipeptide dimerases

inferred← citeshttps://doi.org/10.1039/d0np00010hopenalex-snapshot

Regio- and stereoselective intermolecular phenol coupling enzymes in secondary metabolite biosynthesis

inferred← citeshttps://doi.org/10.1039/d0np00066copenalex-snapshot

Bacterial terpenome

inferred← citeshttps://doi.org/10.1039/d0np00098aopenalex-snapshot

Beyond peptide bond formation: the versatile role of condensation domains in natural product biosynthesis

inferred← citeshttps://doi.org/10.1039/d1np00017aopenalex-snapshot

Recent advances in the biosynthesis strategies of nitrogen heterocyclic natural products

inferred← citeshttps://doi.org/10.1039/d1np00043hopenalex-snapshot

The tryptophan connection: cyclic peptide natural products linked via the tryptophan side chain

inferred← citeshttps://doi.org/10.1039/d1np90021hopenalex-snapshot

Correction: Regio- and stereoselective intermolecular phenol coupling enzymes in secondary metabolite biosynthesis

inferred← citeshttps://doi.org/10.1039/d2np00006gopenalex-snapshot

Chemical synthesis in competition with global genome mining and heterologous expression for the preparation of dimeric tryptophan-derived 2,5-dioxopiperazines

inferred← citeshttps://doi.org/10.1039/d4sc07300bopenalex-snapshot

Characterization of a C-methyltransferase from Streptomyces griseoviridis – crystal structure, mechanism, and substrate scope

inferred← citeshttps://doi.org/10.1080/14786419.2022.2099391openalex-snapshot

A new diketopiperazine-type alkaloid from the endophytic fungus Penicillium expansum

inferred← citeshttps://doi.org/10.1080/21501203.2022.2069173openalex-snapshot

Novel indole diketopiperazine stereoisomers from a marine-derived fungus Aspergillus sp.

inferred← citeshttps://doi.org/10.1093/lambio/ovae086openalex-snapshot

Antimicrobial potential of Streptomyces sp. NP73 isolated from the forest soil of Northeast India against multi-drug resistant Escherichia coli

inferred← citeshttps://doi.org/10.1099/acmi.0.000629.v4openalex-snapshot

Identification of secondary metabolites containing a diketopiperazine core in extracts from myxobacterial strains with growth inhibition activity against a range of prey species

inferred← citeshttps://doi.org/10.1128/aem.02525-20openalex-snapshot

Deciphering a Cyclodipeptide Synthase Pathway Encoding Prenylated Indole Alkaloids in Streptomyces leeuwenhoekii

inferred← citeshttps://doi.org/10.1186/s12934-020-01432-yopenalex-snapshot

In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli

inferred← citeshttps://doi.org/10.1186/s12934-024-02527-6openalex-snapshot

Regulatory mechanism of C4-dicarboxylates in cyclo (Phe-Pro) production

inferred← citeshttps://doi.org/10.1261/rna.075184.120openalex-snapshot

Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates

inferred← citeshttps://doi.org/10.1371/journal.ppat.1007815openalex-snapshot

Amino acid–derived quorum sensing molecules controlling the virulence of vibrios (and beyond)

inferred← citeshttps://doi.org/10.21203/rs.3.rs-4715743/v1openalex-snapshot

A global atlas of fungal biosynthetic gene clusters reveals the diversification of diketopiperazine biosynthesis

inferred← citeshttps://doi.org/10.2139/ssrn.5413038openalex-snapshot

Active secondary metabolites from root-associated endophytic fungus Aspergillus tubingensis ZMGR14 and their activities against plant pathogenic fungi

inferred← citeshttps://doi.org/10.2174/0929866527666200212123542openalex-snapshot

Self-Assembly of Cyclic Dipeptides: Platforms for Functional Materials

inferred← citeshttps://doi.org/10.2174/0929867329666220801143650openalex-snapshot

2,5-Diketopiperazines: A Review of Source, Synthesis, Bioactivity, Structure, and MS Fragmentation

inferred← citeshttps://doi.org/10.25135/rnp.450.2401.3022openalex-snapshot

A New Butoxy Substituted Indolediketopiperazine from the Marine Derived Fungus Aspergillus sp. 66may

inferred← citeshttps://doi.org/10.26686/wgtn.17147699.v1openalex-snapshot

Discovery and Biosynthesis of Natural Products from New Zealand Soil Metagenome Libraries

inferred← citeshttps://doi.org/10.3389/fmicb.2022.860009openalex-snapshot

Antibacterial Activity of Two Metabolites Isolated From Endophytic Bacteria Bacillus velezensis Ea73 in Ageratina adenophora

inferred← citeshttps://doi.org/10.3390/biom11101515openalex-snapshot

Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold

inferred← citeshttps://doi.org/10.3390/fermentation9060576openalex-snapshot

Exploration of Natural Product Repository by Combined Genomics and Metabolomics Profiling of Mangrove-Derived Streptomyces murinus THV12 Strain

inferred← citeshttps://doi.org/10.3390/iecbm2020-08804openalex-snapshot

Ultra-Short Cyclo-Peptides as Bio-Inspired Therapeutics: Proline-Based 2,5-Diketopiperazines (DKP)

inferred← citeshttps://doi.org/10.3390/ijms241713534openalex-snapshot

Advancement from Small Peptide Pharmaceuticals to Orally Active Piperazine-2,5-dion-Based Cyclopeptides

inferred← citeshttps://doi.org/10.3390/md17100551openalex-snapshot

Double the Chemistry, Double the Fun: Structural Diversity and Biological Activity of Marine-Derived Diketopiperazine Dimers

inferred← citeshttps://doi.org/10.3390/md19080403openalex-snapshot

Structures and Biological Activities of Diketopiperazines from Marine Organisms: A Review

inferred← citeshttps://doi.org/10.3390/md19110645openalex-snapshot

Untapped Potential of Marine-Associated Cladosporium Species: An Overview on Secondary Metabolites, Biotechnological Relevance, and Biological Activities

inferred← citeshttps://doi.org/10.3390/md21060325openalex-snapshot

Design, Synthesis, and Anticancer Activity of Novel 3,6-Diunsaturated 2,5-Diketopiperazines

inferred← citeshttps://doi.org/10.3390/molecules26113376openalex-snapshot

Diketopiperazine Gels: New Horizons from the Self-Assembly of Cyclic Dipeptides

inferred← citeshttps://doi.org/10.3390/molecules26237197openalex-snapshot

Lentzeacins A-E, New Bacterial-Derived 2,5- and 2,6-Disubstituted Pyrazines from a BGC-Rich Soil Bacterium Lentzea sp. GA3-008

inferred← citeshttps://doi.org/10.3390/molecules27217585openalex-snapshot

Bispyrrolidinoindoline Epi(poly)thiodioxopiperazines (BPI-ETPs) and Simplified Mimetics: Structural Characterization, Bioactivities, and Total Synthesis

inferred← citeshttps://doi.org/10.3390/molecules30040860openalex-snapshot

In Vitro and In Silico Studies of Maculosin as a Melanogenesis and Tyrosinase Inhibitor

inferred← citeshttps://doi.org/10.3390/molecules31010149openalex-snapshot

Isolation of Three New Diketopiperazine Alkaloids from Penicillium sp. SCH3-Sd2

inferred← citeshttps://doi.org/10.3390/ph19081191openalex-snapshot

Computational and Cellular Evaluation of the Anti-Melanogenic Potential of Gancidin W: Integrating Network Pharmacology and Free-Energy Analyses

inferred← citeshttps://doi.org/10.3390/toxins16030141openalex-snapshot

Inhibition of Aflatoxin Production in Aspergillus flavus by a Klebsiella sp. and Its Metabolite Cyclo(l-Ala-Gly)

inferred← citeshttps://doi.org/10.6084/m9.figshare.12926157openalex-snapshot

Additional file 1 of In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli

inferred← citeshttps://doi.org/10.6084/m9.figshare.12926160openalex-snapshot

Additional file 2 of In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli

inferred← citeshttps://doi.org/10.70675/25f4ecbcz5186z4360z825bz78dff50baba1openalex-snapshot

New insights into the recognition of the substrates of cyclodipeptide synthases

inferred← citeshttps://doi.org/10.70675/a88cca75z731fz450fz8b22z9cce7cf39e4eopenalex-snapshot

Modulation of the secondary metabolism of a Cophinforma mamane endophytic fungal strain by epigenetics and cultivation-based approaches

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.