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Lactobacillus casei LH23 modulates the immune response and ameliorates DSS-induced colitis via suppressing JNK/p-38 signal pathways and enhancing histone H3K9 acetylation

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ibd.21479openalex-snapshot
Colitis locus on chromosome 2 impacting the severity of early-onset disease in mice deficient in GPX1 and GPX2
inferredcites →https://doi.org/10.1007/bf02931595openalex-snapshot
Oral administration of probiotic bacteria (E. coli nissle,E. coli O83,Lactobacillus casei) influences the severity of dextran sodium sulfate-induced colitis in BALB/c mice
inferredcites →https://doi.org/10.1007/s00394-011-0235-yopenalex-snapshot
Influence of extra virgin olive oil diet enriched with hydroxytyrosol in a chronic DSS colitis model
inferredcites →https://doi.org/10.1007/s00394-019-02001-9openalex-snapshot
Lactobacillus casei protects dextran sodium sulfate- or rapamycin-induced colonic inflammation in the mouse
inferredcites →https://doi.org/10.1007/s00535-016-1242-9openalex-snapshot
Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases
inferredcites →https://doi.org/10.1007/s10495-011-0630-0openalex-snapshot
Review: milk fat globule-EGF factor 8 expression, function and plausible signal transduction in resolving inflammation
inferredcites →https://doi.org/10.1007/s10856-016-5812-4openalex-snapshot
A multi-material coating containing chemically-modified apatites for combined enhanced bioactivity and reduced infection via a drop-on-demand micro-dispensing technique
inferredcites →https://doi.org/10.1007/s10856-016-5821-3openalex-snapshot
Expression of CD68 positive macrophages in the use of different barrier materials to prevent peritoneal adhesions—an animal study
inferredcites →https://doi.org/10.1007/s11596-019-2045-zopenalex-snapshot
Probiotic Mixture VSL#3 Alleviates Dextran Sulfate Sodium-induced Colitis in Mice by Downregulating T Follicular Helper Cells
inferredcites →https://doi.org/10.1016/0016-5085(84)90202-6openalex-snapshot
Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity
inferredcites →https://doi.org/10.1016/j.gtc.2012.08.007openalex-snapshot
Probiotics in the Development and Treatment of Allergic Disease
inferredcites →https://doi.org/10.1016/j.ijfoodmicro.2004.11.032openalex-snapshot
Probiotic effects of Lactobacillus casei on DSS-induced ulcerative colitis in mice
inferredcites →https://doi.org/10.1016/j.ijpharm.2017.05.049openalex-snapshot
Synbiotic loaded chitosan-Ca-alginate microparticles reduces inflammation in the TNBS model of rat colitis
inferredcites →https://doi.org/10.1016/j.immuni.2012.08.026openalex-snapshot
Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells
inferredcites →https://doi.org/10.1016/j.intimp.2016.03.033openalex-snapshot
Live and heat-killed probiotic Lactobacillus casei Lbs2 protects from experimental colitis through Toll-like receptor 2-dependent induction of T-regulatory response
inferredcites →https://doi.org/10.1016/j.intimp.2017.07.023openalex-snapshot
Sodium butyrate inhibits the NF-kappa B signaling pathway and histone deacetylation, and attenuates experimental colitis in an IL-10 independent manner
inferredcites →https://doi.org/10.1016/j.jff.2015.05.021openalex-snapshot
Probiotic Lactobacillus casei Shirota improves kidney function, inflammation and bowel movements in hospitalized patients with acute gastroenteritis – A prospective study
inferredcites →https://doi.org/10.1016/j.jff.2016.09.011openalex-snapshot
A mixture of the probiotic strains Bifidobacterium longum CH57 and Lactobacillus brevis CH23 ameliorates colitis in mice by inhibiting macrophage activation and restoring the Th17/Treg balance
inferredcites →https://doi.org/10.1016/j.jnutbio.2010.07.009openalex-snapshot
Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils
inferredcites →https://doi.org/10.1038/39614openalex-snapshot
A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
inferredcites →https://doi.org/10.1038/labinvest.2013.70openalex-snapshot
Butyric acid attenuates intestinal inflammation in murine DSS-induced colitis model via milk fat globule-EGF factor 8
inferredcites →https://doi.org/10.1038/mi.2013.73openalex-snapshot
New targets for mucosal healing and therapy in inflammatory bowel diseases
inferredcites →https://doi.org/10.1038/nature12721openalex-snapshot
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
inferredcites →https://doi.org/10.1038/nri.2016.36openalex-snapshot
Development and maintenance of intestinal regulatory T cells
inferredcites →https://doi.org/10.1038/srep16148openalex-snapshot
The effect of short-chain fatty acids on human monocyte-derived dendritic cells
inferredcites →https://doi.org/10.1038/srep24838openalex-snapshot
Microbial metabolite butyrate facilitates M2 macrophage polarization and function
inferredcites →https://doi.org/10.1039/c7fo00593hopenalex-snapshot
Lactobacillus casei CCFM419 attenuates type 2 diabetes via a gut microbiota dependent mechanism
inferredcites →https://doi.org/10.1039/c8fo02301hopenalex-snapshot
Protective effects of a novel probiotic strain, Lactococcus lactis ML2018, in colitis: in vivo and in vitro evidence
inferredcites →https://doi.org/10.1053/gast.2001.27224openalex-snapshot
Probiotic bacteria enhance murine and human intestinal epithelial barrier function
inferredcites →https://doi.org/10.1073/pnas.0902869106openalex-snapshot
CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease
inferredcites →https://doi.org/10.1073/pnas.1322269111openalex-snapshot
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
inferredcites →https://doi.org/10.1080/10408398.2011.619671openalex-snapshot
Immune System Stimulation by Probiotic Microorganisms
inferredcites →https://doi.org/10.1097/mib.0b013e31829ed7dfopenalex-snapshot
Keeping the Bowel Regular
inferredcites →https://doi.org/10.1111/bph.13637openalex-snapshot
An orally administered butyrate‐releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium‐induced murine colitis
inferredcites →https://doi.org/10.1111/j.1365-2249.2005.02790.xopenalex-snapshot
Probiotic Lactobacillus -induced improvement in murine chronic inflammatory bowel disease is associated with the down-regulation of pro-inflammatory cytokines in lamina propria mononuclear cells
inferredcites →https://doi.org/10.1111/j.1365-2567.2004.01984.xopenalex-snapshot
Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle
inferredcites →https://doi.org/10.1111/j.1365-2567.2008.02942.xopenalex-snapshot
A component of polysaccharide peptidoglycan complex on Lactobacillus induced an improvement of murine model of inflammatory bowel disease and colitis‐associated cancer
inferredcites →https://doi.org/10.1126/science.1241165openalex-snapshot
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
inferredcites →https://doi.org/10.1128/aem.01360-15openalex-snapshot
Attenuation of Colitis by Lactobacillus casei BL23 Is Dependent on the Dairy Delivery Matrix
inferredcites →https://doi.org/10.1128/aem.04134-15openalex-snapshot
Fermented Milk Containing Lactobacillus casei Strain Shirota Preserves the Diversity of the Gut Microbiota and Relieves Abdominal Dysfunction in Healthy Medical Students Exposed to Academic Stress
inferredcites →https://doi.org/10.1128/cvi.00161-06openalex-snapshot
Probiotics Stimulate Production of Natural Antibodies in Chickens
inferredcites →https://doi.org/10.1136/gut.2005.078303openalex-snapshot
Bacterial and fungal microbiota in relation to probiotic therapy (VSL#3) in pouchitis
inferredcites →https://doi.org/10.1136/gut.28.10.1221openalex-snapshot
Short chain fatty acids in human large intestine, portal, hepatic and venous blood.
inferredcites →https://doi.org/10.1136/gutjnl-2014-308514openalex-snapshot
Does the microbiota play a role in the pathogenesis of autoimmune diseases?
inferredcites →https://doi.org/10.1159/000334679openalex-snapshot
Roles of Milk Fat Globule-Epidermal Growth Factor 8 in Intestinal Inflammation
inferredcites →https://doi.org/10.1177/0394632015590948openalex-snapshot
Evaluation of resistance to low pH and bile salts of human Lactobacillus spp. isolates
inferredcites →https://doi.org/10.1371/journal.pone.0027961openalex-snapshot
Lysate of Probiotic Lactobacillus casei DN-114 001 Ameliorates Colitis by Strengthening the Gut Barrier Function and Changing the Gut Microenvironment
inferredcites →https://doi.org/10.3168/jds.2018-16197openalex-snapshot
Lactobacillus plantarum CAU1055 ameliorates inflammation in lipopolysaccharide-induced RAW264.7 cells and a dextran sulfate sodium–induced colitis animal model
inferredcites →https://doi.org/10.3920/bm2015.0109openalex-snapshot
Anti-inflammatory effects of Lactobacillus brevis K65 on RAW 264.7 cells and in mice with dextran sulphate sodium-induced ulcerative colitis
inferredcites →https://doi.org/10.7150/ijbs.8879openalex-snapshot
Macrophage Polarization in Inflammatory Diseases

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4656898openalex-extracted
Regulatory Effects of Green Tea Polyphenols on the Gut Bacteriophages: An in Vitro Study
inferred← citeshttps://doi.org/10.1002/advs.78105openalex-snapshot
A Postbiotic‐Inducing Ganoderma applanatum Polysaccharide Repairs the Intestinal Barrier via a Phocaeicola vulgatus ‐ Tridecylic Acid Axis
inferred← citeshttps://doi.org/10.1002/fsn3.3282openalex-snapshot
Chimonanthus salicifolius extract alleviates DSS‐induced colitis and regulates gut microbiota in mice
inferred← citeshttps://doi.org/10.1002/iid3.1045openalex-snapshot
Mechanistic insights into the role of probiotics in modulating immune cells in ulcerative colitis
inferred← citeshttps://doi.org/10.1002/jsfa.12334openalex-snapshot
Aspergillus cristatus attenuates DSS ‐induced intestinal barrier damage through reducing the oxidative stress, regulating short‐chain fatty acid and inhibiting MAPK signaling pathways
inferred← citeshttps://doi.org/10.1007/978-3-030-64668-4_18openalex-snapshot
Probiotics in Colon Cancer: A Therapeutic Approach
inferred← citeshttps://doi.org/10.1007/s10787-022-01085-wopenalex-snapshot
Curcumin analog C66 alleviates inflammatory colitis by inhibiting the activation of NF-κB
inferred← citeshttps://doi.org/10.1007/s11010-026-05597-9openalex-snapshot
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Comparative efficacy of exercise training processes in improving nonalcoholic fatty liver disease: a systematic review and meta-analysis
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Mannobiose Production Through Synergistic Enzymatic Hydrolysis of Locust Bean Gum by Mannanases from Alkaliphilic Bacillus sp. N16-5
inferred← citeshttps://doi.org/10.1007/s12602-021-09848-7openalex-snapshot
Lacticaseibacillus casei LH23 Suppressed HPV Gene Expression and Inhibited Cervical Cancer Cells
inferred← citeshttps://doi.org/10.1007/s12602-025-10666-4openalex-snapshot
Optimization of Production Conditions for Extracellular Vesicles from Lacticaseibacillus Paracasei LH23 Using Response Surface Methodology: Enhancement of Yield and Exploration of Stability, Safety, and Anti-inflammatory Capacity
inferred← citeshttps://doi.org/10.1007/s12672-025-01996-4openalex-snapshot
Probiotics in colorectal cancer prevention and therapy: mechanisms, benefits, and challenges
inferred← citeshttps://doi.org/10.1016/b978-0-12-823733-5.00016-7openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/b978-0-323-99111-7.00012-xopenalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.bbrc.2022.03.024openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114950openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117977openalex-snapshot
Blautia wexlerae ameliorates ulcerative colitis via metabolic remodeling of the gut microbiota
inferred← citeshttps://doi.org/10.1016/j.foodchem.2026.150253openalex-snapshot
Molecular crosstalk of probiotics in gut health: A chemical perspective on metabolite-mediated pathways
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.129468openalex-snapshot
Sodium carboxymethyl celluloses as a cryoprotectant for survival improvement of lactic acid bacterial strains subjected to freeze-drying
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.140287openalex-snapshot
Lactobacillus acidophilus YL01 and its exopolysaccharides ameliorate obesity and insulin resistance in obese mice via modulating intestinal specific bacterial groups and AMPK/ACC signaling pathway
inferred← citeshttps://doi.org/10.1016/j.jafr.2026.102809openalex-snapshot
Oat bran ameliorated DSS-induced mice colitis by suppressing inflammation and enriching beneficial metabolites derived from gut microbiota
inferred← citeshttps://doi.org/10.1016/j.jare.2024.09.029openalex-snapshot
The role of JNK signaling pathway in organ fibrosis
inferred← citeshttps://doi.org/10.1016/j.jff.2022.105030openalex-snapshot
Bifidobacterium longum subsp. longum K5 alleviates inflammatory response and prevents intestinal barrier injury induced by LPS in vitro based on comparative genomics
inferred← citeshttps://doi.org/10.1016/j.jff.2023.105435openalex-snapshot
Mixed Lactiplantibacillus plantarum strains alleviated DSS-induced intestinal inflammation of Balb/c mice via the 5-HT/5-HT7R/NF-κB signaling pathway
inferred← citeshttps://doi.org/10.1016/j.micres.2024.127928openalex-snapshot
From probiotic chassis to modification strategies, control and improvement of genetically engineered probiotics for inflammatory bowel disease
inferred← citeshttps://doi.org/10.1016/j.nantod.2024.102210openalex-snapshot
Multi-prospects of bacterial extracellular vesicles in immune modulation, inflammation regulation, and periodontitis treatment
inferred← citeshttps://doi.org/10.1016/j.phrs.2026.109663openalex-snapshot
Immunometabolism of tumor-associated macrophages in driving colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.psj.2021.101283openalex-snapshot
Lactobacillus casei protects intestinal mucosa from damage in chicks caused by Salmonella pullorum via regulating immunity and the Wnt signaling pathway and maintaining the abundance of gut microbiota
inferred← citeshttps://doi.org/10.1016/j.tifs.2023.06.007openalex-snapshot
Exploiting lactic acid bacteria for inflammatory bowel disease: A recent update
inferred← citeshttps://doi.org/10.1038/s41522-026-00938-4openalex-snapshot
Maternal gut microbial legacy shapes intestinal health and susceptibility of offspring to colitis
inferred← citeshttps://doi.org/10.1039/d1fo01558copenalex-snapshot
The preventive effect and underlying mechanism of Rhus chinensis Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice
inferred← citeshttps://doi.org/10.1039/d1fo03334dopenalex-snapshot
Protective effects of chlorogenic acid on trimethyltin chloride-induced neurobehavioral dysfunctions in mice relying on the gut microbiota
inferred← citeshttps://doi.org/10.1039/d1fo03677gopenalex-snapshot
Ganoderma applanatum polysaccharides and ethanol extracts promote the recovery of colitis through intestinal barrier protection and gut microbiota modulations
inferred← citeshttps://doi.org/10.1039/d2fo02567aopenalex-snapshot
Lactobacillus plantarum ZJ316 alleviates ulcerative colitis by inhibiting inflammation and regulating short-chain fatty acid levels and the gut microbiota in a mouse model
inferred← citeshttps://doi.org/10.1039/d3fo00354jopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/d4fo01794copenalex-snapshot
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