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Plant-based engineering for production of high-valued natural products
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/anie.201510650openalex-snapshot
Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial Biosynthesis
inferredcites →https://doi.org/10.1002/bit.20237openalex-snapshot
Metabolic engineering of isoprenoid biosynthesis in Arabidopsis for the production of taxadiene, the first committed precursor of Taxol
inferredcites →https://doi.org/10.1002/cbic.201800592openalex-snapshot
Gene Discovery in Gelsemium Highlights Conserved Gene Clusters in Monoterpene Indole Alkaloid Biosynthesis
inferredcites →https://doi.org/10.1002/med.21657openalex-snapshot
Artemisinin‐derived antimalarial endoperoxides from bench‐side to bed‐side: Chronological advancements and future challenges
inferredcites →https://doi.org/10.1006/abbi.2000.1962openalex-snapshot
Molecular Cloning, Expression, and Characterization of Amorpha-4,11-diene Synthase, a Key Enzyme of Artemisinin Biosynthesis in Artemisia annua L.
inferredcites →https://doi.org/10.1006/anbo.1997.0525openalex-snapshot
Histochemical Localization of Citral Accumulation in Lemongrass Leaves (Cymbopogon citratus(DC.) Stapf., Poaceae)
inferredcites →https://doi.org/10.1007/s00299-014-1568-9openalex-snapshot
Metabolic engineering of Nicotiana benthamiana for the increased production of taxadiene
inferredcites →https://doi.org/10.1007/s00299-016-1937-7openalex-snapshot
Site-directed mutagenesis in Petunia × hybrida protoplast system using direct delivery of purified recombinant Cas9 ribonucleoproteins
inferredcites →https://doi.org/10.1007/s00299-018-2293-6openalex-snapshot
Physcomitrella patens, a versatile synthetic biology chassis
inferredcites →https://doi.org/10.1007/s00425-021-03626-zopenalex-snapshot
Importation of taxadiene synthase into chloroplast improves taxadiene production in tobacco
inferredcites →https://doi.org/10.1007/s00709-018-1233-1openalex-snapshot
Overexpression of tryptophan decarboxylase and strictosidine synthase enhanced terpenoid indole alkaloid pathway activity and antineoplastic vinblastine biosynthesis in Catharanthus roseus
inferredcites →https://doi.org/10.1007/s11248-006-9039-xopenalex-snapshot
Redirection of carotenoid metabolism for the efficient production of taxadiene [taxa-4(5),11(12)-diene] in transgenic tomato fruit
inferredcites →https://doi.org/10.1007/s11248-009-9252-5openalex-snapshot
Production of taxa-4(5),11(12)-diene by transgenic Physcomitrella patens
inferredcites →https://doi.org/10.1007/s11816-015-0353-8openalex-snapshot
Sclareol production in the moss Physcomitrella patens and observations on growth and terpenoid biosynthesis
inferredcites →https://doi.org/10.1007/s13205-017-0848-9openalex-snapshot
Plant-derived antimicrobials to fight against multi-drug-resistant human pathogens
inferredcites →https://doi.org/10.1007/s40610-017-0053-yopenalex-snapshot
Assembly of Dynamic P450-Mediated Metabolons—Order Versus Chaos
inferredcites →https://doi.org/10.1016/j.bbrc.2018.04.092openalex-snapshot
Evaluation of synthetic promoters in Physcomitrella patens
inferredcites →https://doi.org/10.1016/j.biortech.2007.06.061openalex-snapshot
Yield enhancement strategies for artemisinin production by suspension cultures of Artemisia annua
inferredcites →https://doi.org/10.1016/j.bmcl.2015.07.014openalex-snapshot
Cheminformatic comparison of approved drugs from natural product versus synthetic origins
inferredcites →https://doi.org/10.1016/j.cpb.2019.100121openalex-snapshot
The production of plant natural products beneficial to humanity by metabolic engineering
inferredcites →https://doi.org/10.1016/j.ejmech.2018.12.007openalex-snapshot
Current scenario of artemisinin and its analogues for antimalarial activity
inferredcites →https://doi.org/10.1016/j.indcrop.2012.12.004openalex-snapshot
A survey of artemisinic and dihydroartemisinic acid contents in glasshouse and global field-grown populations of the artemisinin-producing plant Artemisia annua L.
inferredcites →https://doi.org/10.1016/j.jbiotec.2013.04.004openalex-snapshot
Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest
inferredcites →https://doi.org/10.1016/j.molp.2019.06.001openalex-snapshot
The Structure and Function of Major Plant Metabolite Modifications
inferredcites →https://doi.org/10.1016/j.pbi.2005.03.014openalex-snapshot
Metabolon formation and metabolic channeling in the biosynthesis of plant natural products
inferredcites →https://doi.org/10.1016/j.pbi.2015.04.001openalex-snapshot
Breaking new ground in the regulation of the early steps of plant isoprenoid biosynthesis
inferredcites →https://doi.org/10.1016/j.phytochem.2007.06.033openalex-snapshot
Metabolon formation in dhurrin biosynthesis
inferredcites →https://doi.org/10.1016/j.phytol.2014.06.015openalex-snapshot
Alkaloids as drug leads – A predictive structural and biodiversity-based analysis
inferredcites →https://doi.org/10.1016/j.scienta.2018.08.040openalex-snapshot
Enhancement of tomato resistance to Tuta absoluta using a new efficient mesoporous silica nanoparticle-mediated plant transient gene expression approach
inferredcites →https://doi.org/10.1016/j.tibtech.2019.10.009openalex-snapshot
Synthetic Protein Scaffolding at Biological Membranes
inferredcites →https://doi.org/10.1016/j.tplants.2014.11.002openalex-snapshot
Plasticity of specialized metabolism as mediated by dynamic metabolons
inferredcites →https://doi.org/10.1016/j.tplants.2019.03.006openalex-snapshot
Laticifers, Latex, and Their Role in Plant Defense
inferredcites →https://doi.org/10.1016/j.ymben.2017.06.012openalex-snapshot
A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules
inferredcites →https://doi.org/10.1016/j.ymben.2017.09.014openalex-snapshot
Tat proteins as novel thylakoid membrane anchors organize a biosynthetic pathway in chloroplasts and increase product yield 5-fold
inferredcites →https://doi.org/10.1021/acscentsci.0c00241openalex-snapshot
Engineering Plant Synthetic Pathways for the Biosynthesis of Novel Antifungals
inferredcites →https://doi.org/10.1021/acssynbio.7b00368openalex-snapshot
Co-Compartmentation of Terpene Biosynthesis and Storage via Synthetic Droplet
inferredcites →https://doi.org/10.1021/jacs.9b05999openalex-snapshot
Biosynthesis of an Anti-Addiction Agent from the Iboga Plant
inferredcites →https://doi.org/10.1021/jacs.9b10717openalex-snapshot
Total Biosynthesis for Milligram-Scale Production of Etoposide Intermediates in a Plant Chassis
inferredcites →https://doi.org/10.1038/530390aopenalex-snapshot
Synthetic biology’s first malaria drug meets market resistance
inferredcites →https://doi.org/10.1038/nature04640openalex-snapshot
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
inferredcites →https://doi.org/10.1038/nature09524openalex-snapshot
Integrating carbon–halogen bond formation into medicinal plant metabolism
inferredcites →https://doi.org/10.1038/nature12051openalex-snapshot
High-level semi-synthetic production of the potent antimalarial artemisinin
inferredcites →https://doi.org/10.1038/nbt.2054openalex-snapshot
Generation of the potent anti-malarial drug artemisinin in tobacco
inferredcites →https://doi.org/10.1038/nbt1251openalex-snapshot
Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants
inferredcites →https://doi.org/10.1038/nbt833openalex-snapshot
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
inferredcites →https://doi.org/10.1038/ncomms14261openalex-snapshot
Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes
inferredcites →https://doi.org/10.1038/nrmicro3240openalex-snapshot
Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development
inferredcites →https://doi.org/10.1038/s41467-017-01067-5openalex-snapshot
Echinochloa crus-galli genome analysis provides insight into its adaptation and invasiveness as a weed
inferredcites →https://doi.org/10.1038/s41467-018-04543-8openalex-snapshot
The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
inferredcites →https://doi.org/10.1038/s41467-019-08515-4openalex-snapshot
Cytosolic lipid droplets as engineered organelles for production and accumulation of terpenoid biomaterials in leaves
inferredcites →https://doi.org/10.1038/s41467-019-09848-wopenalex-snapshot
Synthetic biology strategies for microbial biosynthesis of plant natural products
inferredcites →https://doi.org/10.1038/s41467-019-12879-yopenalex-snapshot
Chloroplastic metabolic engineering coupled with isoprenoid pool enhancement for committed taxanes biosynthesis in Nicotiana benthamiana
inferredcites →https://doi.org/10.1038/s41467-020-19153-6openalex-snapshot
Formation and diversification of a paradigm biosynthetic gene cluster in plants
inferredcites →https://doi.org/10.1038/s41477-019-0461-5openalex-snapshot
The emerging and uncultivated potential of CRISPR technology in plant science
inferredcites →https://doi.org/10.1038/s41477-021-00963-5openalex-snapshot
The Taxus genome provides insights into paclitaxel biosynthesis
inferredcites →https://doi.org/10.1038/s41565-019-0382-5openalex-snapshot
High aspect ratio nanomaterials enable delivery of functional genetic material without DNA integration in mature plants
inferredcites →https://doi.org/10.1038/s41573-020-00114-zopenalex-snapshot
Natural products in drug discovery: advances and opportunities
inferredcites →https://doi.org/10.1038/s41587-019-0337-2openalex-snapshot
Plant gene editing through de novo induction of meristems
inferredcites →https://doi.org/10.1038/s41587-020-0703-0openalex-snapshot
A GRF–GIF chimeric protein improves the regeneration efficiency of transgenic plants
inferredcites →https://doi.org/10.1038/srep25030openalex-snapshot
In vivo assembly of DNA-fragments in the moss, Physcomitrella patens
inferredcites →https://doi.org/10.1039/c3mb70579jopenalex-snapshot
A red light-controlled synthetic gene expression switch for plant systems
inferredcites →https://doi.org/10.1039/c6np00035eopenalex-snapshot
Computational genomic identification and functional reconstitution of plant natural product biosynthetic pathways
inferredcites →https://doi.org/10.1039/c8np00037aopenalex-snapshot
Dynamic metabolic solutions to the sessile life style of plants
inferredcites →https://doi.org/10.1042/ba20080068openalex-snapshot
Development of transgenic Artemisia annua (Chinese wormwood) plants with an enhanced content of artemisinin, an effective anti‐malarial drug, by hairpin‐RNA‐mediated gene silencing
inferredcites →https://doi.org/10.1073/pnas.0911451107openalex-snapshot
Vinca drug components accumulate exclusively in leaf exudates of Madagascar periwinkle
inferredcites →https://doi.org/10.1073/pnas.1818290116openalex-snapshot
DNA nanostructures coordinate gene silencing in mature plants
inferredcites →https://doi.org/10.1073/pnas.1906083116openalex-snapshot
Identification of key enzymes responsible for protolimonoid biosynthesis in plants: Opening the door to azadirachtin production
inferredcites →https://doi.org/10.1073/pnas.1914373117openalex-snapshot
Genomic evidence for convergent evolution of gene clusters for momilactone biosynthesis in land plants
inferredcites →https://doi.org/10.1073/pnas.2007934117openalex-snapshot
Why are momilactones always associated with biosynthetic gene clusters in plants?
inferredcites →https://doi.org/10.1093/jxb/erw067openalex-snapshot
Transfer of the cytochrome P450-dependent dhurrin pathway from Sorghum bicolor into Nicotiana tabacum chloroplasts for light-driven synthesis
inferredcites →https://doi.org/10.1093/nar/gkx305openalex-snapshot
plantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters
inferredcites →https://doi.org/10.1093/nar/gkx404openalex-snapshot
The PhytoClust tool for metabolic gene clusters discovery in plant genomes
inferredcites →https://doi.org/10.1093/pcp/pcv131openalex-snapshot
Engineering a Platform for Photosynthetic Pigment, Hormone and Cembrane-Related Diterpenoid Production in Nicotiana tabacum
inferredcites →https://doi.org/10.1093/pcp/pcy004openalex-snapshot
Metabolic Flux Engineering of Cembratrien-ol Production in Both the Glandular Trichome and Leaf Mesophyll in Nicotiana tabacum
inferredcites →https://doi.org/10.1093/plcell/koaa023openalex-snapshot
Interdependent evolution of biosynthetic gene clusters for momilactone production in rice
inferredcites →https://doi.org/10.1104/pp.011001openalex-snapshot
Methyl Jasmonate Induces Traumatic Resin Ducts, Terpenoid Resin Biosynthesis, and Terpenoid Accumulation in Developing Xylem of Norway Spruce Stems
inferredcites →https://doi.org/10.1104/pp.16.01942openalex-snapshot
Genome-Wide Prediction of Metabolic Enzymes, Pathways, and Gene Clusters in Plants
inferredcites →https://doi.org/10.1105/tpc.16.00124openalex-snapshot
Morphogenic Regulators Baby boom and Wuschel Improve Monocot Transformation
inferredcites →https://doi.org/10.1111/nph.13629openalex-snapshot
Monoterpene biosynthesis potential of plant subcellular compartments
inferredcites →https://doi.org/10.1111/nph.16283openalex-snapshot
Glandular trichomes: micro‐organs with model status?
inferredcites →https://doi.org/10.1111/nph.16562openalex-snapshot
Beyond natural: synthetic expansions of botanical form and function
inferredcites →https://doi.org/10.1111/nph.16631openalex-snapshot
Doing the gene shuffle to close synteny: dynamic assembly of biosynthetic gene clusters
inferredcites →https://doi.org/10.1111/nph.16777openalex-snapshot
TRICHOME AND ARTEMISININ REGULATOR 2 positively regulates trichome development and artemisinin biosynthesis in Artemisia annua
inferredcites →https://doi.org/10.1111/pbi.12933openalex-snapshot
Engineering storage capacity for volatile sesquiterpenes in Nicotiana benthamiana leaves
inferredcites →https://doi.org/10.1111/pbi.13135openalex-snapshot
Characterizing standard genetic parts and establishing common principles for engineering legume and cereal roots
inferredcites →https://doi.org/10.1111/poms.12574openalex-snapshot
Interventions for an Artemisinin‐based Malaria Medicine Supply Chain
inferredcites →https://doi.org/10.1111/tpj.14725openalex-snapshot
A plastid‐localized bona fide geranylgeranyl diphosphate synthase plays a necessary role in monoterpene indole alkaloid biosynthesis in Catharanthus roseus
inferredcites →https://doi.org/10.1126/science.1155165openalex-snapshot
Qinghaosu (Artemisinin): The Price of Success
inferredcites →https://doi.org/10.1126/science.1182612openalex-snapshot
The Genetic Map of Artemisia annua L. Identifies Loci Affecting Yield of the Antimalarial Drug Artemisinin
inferredcites →https://doi.org/10.1126/science.277.5326.696openalex-snapshot
Analysis of a Chemical Plant Defense Mechanism in Grasses
inferredcites →https://doi.org/10.1126/science.aac7202openalex-snapshot
Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone
inferredcites →https://doi.org/10.1126/science.aac9373openalex-snapshot
Complete biosynthesis of opioids in yeast
inferredcites →https://doi.org/10.1126/science.aag2347openalex-snapshot
Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum
inferredcites →https://doi.org/10.1126/science.aat4096openalex-snapshot
The opium poppy genome and morphinan production
inferredcites →https://doi.org/10.1126/science.aat4100openalex-snapshot
Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle
inferredcites →https://doi.org/10.1139/gen-2017-0117openalex-snapshot
Genome-wide searches and molecular analyses highlight the unique evolutionary path of flavone synthase I (FNSI) in Apiaceae
inferredcites →https://doi.org/10.1146/annurev-arplant-042110-103814openalex-snapshot
Convergent Evolution in Plant Specialized Metabolism
inferredcites →https://doi.org/10.1146/annurev-arplant-081519-035634openalex-snapshot
Exploring Uncharted Territories of Plant Specialized Metabolism in the Postgenomic Era
inferredcites →https://doi.org/10.1146/annurev-biochem-052010-100934openalex-snapshot
Methylerythritol Phosphate Pathway of Isoprenoid Biosynthesis
inferredcites →https://doi.org/10.1186/1471-2164-12-236openalex-snapshot
Differential phylogenetic expansions in BAHD acyltransferases across five angiosperm taxa and evidence of divergent expression among Populus paralogues
inferredcites →https://doi.org/10.1186/1472-6750-12-34openalex-snapshot
Development of efficient catharanthus roseus regeneration and transformation system using agrobacterium tumefaciens and hypocotyls as explants
inferredcites →https://doi.org/10.1186/2047-217x-3-17openalex-snapshot
Data access for the 1,000 Plants (1KP) project
inferredcites →https://doi.org/10.1186/s12870-021-02840-xopenalex-snapshot
Analysis and review of trichomes in plants
inferredcites →https://doi.org/10.1371/journal.pone.0014222openalex-snapshot
Nicotiana benthamiana as a Production Platform for Artemisinin Precursors
inferredcites →https://doi.org/10.1371/journal.pone.0043038openalex-snapshot
Overexpression of ORCA3 and G10H in Catharanthus roseus Plants Regulated Alkaloid Biosynthesis and Metabolism Revealed by NMR-Metabolomics
inferredcites →https://doi.org/10.1371/journal.pone.0077356openalex-snapshot
System for Stable β-Estradiol-Inducible Gene Expression in the Moss Physcomitrella patens
inferredcites →https://doi.org/10.1371/journal.pone.0184839openalex-snapshot
Metabolic engineering to simultaneously activate anthocyanin and proanthocyanidin biosynthetic pathways in Nicotiana spp.
inferredcites →https://doi.org/10.1371/journal.pone.0243620openalex-snapshot
Connecting moss lipid droplets to patchoulol biosynthesis
inferredcites →https://doi.org/10.3389/fbioe.2017.00047openalex-snapshot
Stable Production of the Antimalarial Drug Artemisinin in the Moss Physcomitrella patens
inferredcites →https://doi.org/10.3389/fmicb.2019.01404openalex-snapshot
A Review of the Microbial Production of Bioactive Natural Products and Biologics
inferredcites →https://doi.org/10.3389/fpls.2016.01904openalex-snapshot
DNA-Free Genetically Edited Grapevine and Apple Protoplast Using CRISPR/Cas9 Ribonucleoproteins
inferredcites →https://doi.org/10.3389/fpls.2017.01966openalex-snapshot
A Review of Biotechnological Artemisinin Production in Plants
inferredcites →https://doi.org/10.3389/fpls.2017.02082openalex-snapshot
A Novel AP2/ERF Transcription Factor CR1 Regulates the Accumulation of Vindoline and Serpentine in Catharanthus roseus
inferredcites →https://doi.org/10.3389/fpls.2018.00087openalex-snapshot
Approaches and Recent Developments for the Commercial Production of Semi-synthetic Artemisinin
inferredcites →https://doi.org/10.3389/fpls.2018.00942openalex-snapshot
Terpene Moiety Enhancement by Overexpression of Geranyl(geranyl) Diphosphate Synthase and Geraniol Synthase Elevates Monomeric and Dimeric Monoterpene Indole Alkaloids in Transgenic Catharanthus roseus
inferredcites →https://doi.org/10.3389/fpls.2019.00618openalex-snapshot
Chemodiversity of the Glucosinolate-Myrosinase System at the Single Cell Type Resolution
inferredcites →https://doi.org/10.3389/fpls.2020.572319openalex-snapshot
Overexpression of the Transcription Factor GROWTH-REGULATING FACTOR5 Improves Transformation of Dicot and Monocot Species
inferredcites →https://doi.org/10.3389/fpls.2020.581675openalex-snapshot
Nicotiana benthamiana as a Transient Expression Host to Produce Auxin Analogs
inferredcites →https://doi.org/10.3389/fpls.2021.691462openalex-snapshot
Utilizing Plant Synthetic Biology to Improve Human Health and Wellness
inferredcites →https://doi.org/10.3390/agronomy11050968openalex-snapshot
Plant Secondary Metabolite Biosynthesis and Transcriptional Regulation in Response to Biotic and Abiotic Stress Conditions
inferredcites →https://doi.org/10.3390/cancers12071721openalex-snapshot
Beyond the Paclitaxel and Vinca Alkaloids: Next Generation of Plant-Derived Microtubule-Targeting Agents with Potential Anticancer Activity
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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In Vivo Assembly in Tobacco Cells to Elucidate and Engineer the Biosynthesis of 4-Hydroxydihydrocinnamaldehyde from Gloriosa Superba
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In vivo assembly in tobacco cells to elucidate and engineer the biosynthesis of 4-hydroxydihydrocinnamaldehyde from Gloriosa superba
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Enhancement of taxans production via Al2O3NPs and WO3 NPs treatment of leaf-derived callus of Corylus avellana
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Enhancement of taxans production via Al2O3NPs and WO3 NPs treatment of leaf-derived callus of Corylus avellana
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Secondary metabolite production in transgenic cultures: an overview over the last decade
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Progress and prospect: Biosynthesis of plant natural products based on plant chassis
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Paeoniflorin attenuates cisplatin induced ototoxicity by inhibiting ferroptosis mediated by HMGB1/NRF2/GPX4 pathway
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Fangchinoline eliminates intracellular Salmonella by enhancing lysosomal function via the AMPK-mTORC1-TFEB axis
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Synthetic biology for plant genetic engineering and molecular farming
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Characterization of a 4′-O-rhamnosyltransferase and de novo biosynthesis of bioactive steroidal triglycosides from Paris polyphylla
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Synthetic Biology in Natural Product Biosynthesis
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Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants
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Using Synthetic Biology to Understand the Function of Plant Specialized Metabolites
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In vivo assembly in tobacco cells to elucidate and engineer the biosynthesis of 4-hydroxydihydrocinnamaldehyde from Gloriosa superba
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TBS-pyrrole as an “universal” reference to quantify artemisinin and structurally-diverse natural products in plants extracts by NMR
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Editorial: Transgenesis and secondary metabolites: recent developments and technological challenges
inferred← citeshttps://doi.org/10.3389/fpls.2024.1420231openalex-snapshot
Non-targeted metabolomics reveals the taste variations during Baccaurea ramiflora Lour. fruit maturation
inferred← citeshttps://doi.org/10.3389/fpls.2025.1565850openalex-snapshot
Beyond the lab: future-proofing agriculture for climate resilience and stress management
inferred← citeshttps://doi.org/10.3390/cimb47090723openalex-snapshot
Metabolic Engineering of Terpenoid Biosynthesis in Medicinal Plants: From Genomic Insights to Biotechnological Applications
inferred← citeshttps://doi.org/10.4995/thesis/10251/200381openalex-snapshot
Production of Recombinant Proteins with Pharmaceutical and Industrial Applications in Plants Using a Tobacco Mosaic Virus-Derived Vector
inferred← citeshttps://doi.org/10.52756/bhstiid.2025.e02.011openalex-snapshot
Pharmacological Uses of New Bioactive Compounds from Medicinal Plants
inferred← citeshttps://doi.org/10.62347/xlzx8935openalex-snapshot
Natural products as inhibitors against pancreatic cancer cell proliferation and invasion: possible mechanisms
inferred← citeshttps://doi.org/10.70675/63486756z3916z4dd6z9701z5a91575bbd5eopenalex-snapshot
Metabolomics-centered exploration of plant specialized metabolism innovations : a case-study on the chemodiversity, biosynthesis and anti-herbivory functions of N-acylnornicotines in the genus Nicotiana
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