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Regioselective synthesis of enantiopure 1,2- and 1,3-dispirooxindoles along with a DFT study

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Recent Developments on the Synthesis and Applications of Natural Products-Inspired Spirooxindole Frameworks
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Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line
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Novel three-component domino reactions of ketones, isatin and amino acids: Synthesis and discovery of antimycobacterial activity of highly functionalised novel dispiropyrrolidines
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A regioselective synthesis of dispiro[oxindole-cyclohexanone]pyrrolidines and dispiro[oxindole-hexahydroindazole]pyrrolidines by sequential 1,3-dipolar cycloaddition and annulation through a microwave induced solvent-free approach
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Recent advances in the synthesis of biologically active spirooxindoles
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Asymmetric synthesis approach of enantiomerically pure spiro-indenoquinoxaline pyrrolidines and spiro-indenoquinoxaline pyrrolizidines
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Cu-mediated 1,3-dipolar cycloaddition of azomethine ylides with dipolarophiles: a faster access to spirooxindoles of potential pharmacological interest
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Diastereo- and Enantioselective Construction of 3,3′-Pyrrolidinyldispirooxindole Framework via Catalytic Asymmetric 1,3-Dipolar Cycloadditions
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β-Functionalization of Indolin-2-one-Derived Aliphatic Acids for the Divergent Synthesis of Spirooxindole γ-Butyrolactones
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Diastereoselective Construction of Indole-Bridged Chroman Spirooxindoles through a TfOH-Catalyzed Michael Addition-Inspired Cascade Reaction
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Access to Chiral 2,5-Pyrrolidinyl Dispirooxindoles via Dinuclear Zinc-Catalyzed Asymmetric Cascade Reactions
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Density Functionals with Broad Applicability in Chemistry
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Computational Methods To Calculate Accurate Activation and Reaction Energies of 1,3-Dipolar Cycloadditions of 24 1,3-Dipoles
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Enantioselective Formal Synthesis of Eurylene: Synthesis of the cis- and trans-THF Fragments Using Oxidative Cyclization
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Lewis Acid Catalyzed Unprecedented [3 + 2] Cycloaddition Yields 3,3′-Pyrrolidinyldispirooxindoles Containing Four Contiguous Chiral Stereocenters with Two Contiguous Quaternary Spirostereocenters
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Catalytic enantioselective cascade Michael/cyclization reaction of 3-isothiocyanato oxindoles with exocyclic α,β-unsaturated ketones en route to 3,2′-pyrrolidinyl bispirooxindoles
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A DBU-catalyzed Michael–Pinner–isomerization cascade reaction of 3-hydroxyoxindoles with isatylidene malononitriles: access to highly functionalized bispirooxindoles containing a fully substituted dihydrofuran motif
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Asymmetric synthesis of trifluoromethyl-substituted 3,3′-pyrrolidinyl-dispirooxindoles through organocatalytic 1,3-dipolar cycloaddition reactions
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Metal-free diastereoselective construction of bridged ketal spirooxindoles via a Michael addition-inspired sequence
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Diastereoselective construction of pyrrolo[2,1- a ]isoquinoline-based bispirooxindoles through a three-component [3 + 2] cycloaddition
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Stereoselective synthesis and applications of spirocyclic oxindoles
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Applications of the Conceptual Density Functional Theory Indices to Organic Chemistry Reactivity
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A Call for a Change in Policy Regarding the Necessity for SDE Tests to Validate the Veracity of the Outcome of Enantioselective Syntheses, the Inherent Chiral State of Natural Products, and Other Cases Involving Enantioenriched Samples

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inferred← citeshttps://doi.org/10.2139/ssrn.4658095openalex-extracted
Dft Study on the Effect of Chloroxime Indole Compounds with Different Substituents on the Mechanism of 1,3-Dipolar Cycloaddition Reaction
inferred← citeshttps://doi.org/10.1038/s41557-025-02041-1openalex-snapshot
Collective asymmetric synthesis of the Strychnos alkaloids via thiophene S,S-dioxide cycloadditions
inferred← citeshttps://doi.org/10.1039/d3ra05587fopenalex-snapshot
Elucidating anticancer drugs release from UiO-66 as a carrier through the computational approaches
inferred← citeshttps://doi.org/10.1039/d5qo01408eopenalex-snapshot
Origin of chemo- and stereoselectivity in NHC-catalyzed asymmetric intermolecular cycloadditions of hydrazone and isatin
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