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Cardiovascular Protective Effects of Centella asiatica and Its Triterpenes: A Review

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jbt.21434openalex-snapshot
Madecassoside, a triterpenoid saponin isolated from Centella asiatica herbs, protects endothelial cells against oxidative stress
inferredcites →https://doi.org/10.1002/jsfa.4454openalex-snapshot
Antioxidant capacity and phenolic composition of fermented Centella asiatica herbal teas
inferredcites →https://doi.org/10.1002/ptr.5110openalex-snapshot
Centella asiatica in Dermatology: An Overview
inferredcites →https://doi.org/10.1002/ptr.5156openalex-snapshot
Asiatic Acid Reduces Blood Pressure by Enhancing Nitric Oxide Bioavailability with Modulation of eNOS and p47phox Expression in l ‐NAME‐induced Hypertensive Rats
inferredcites →https://doi.org/10.1002/ptr.5404openalex-snapshot
Asiaticoside Inhibits TNF-α-Induced Endothelial Hyperpermeability of Human Aortic Endothelial Cells
inferredcites →https://doi.org/10.1007/s00204-015-1477-xopenalex-snapshot
Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets
inferredcites →https://doi.org/10.1007/s00210-017-1408-xopenalex-snapshot
Effect of asiatic acid on the Ang II-AT1R-NADPH oxidase-NF-κB pathway in renovascular hypertensive rats
inferredcites →https://doi.org/10.1007/s00441-012-1437-1openalex-snapshot
Dual role of lipoproteins in endothelial cell dysfunction in atherosclerosis
inferredcites →https://doi.org/10.1007/s10616-018-0198-4openalex-snapshot
Anti inflammatory effect of asiaticoside on human umbilical vein endothelial cells induced by ox-LDL
inferredcites →https://doi.org/10.1007/s11010-017-3199-2openalex-snapshot
Obesity-alleviating potential of asiatic acid and its effects on ACC1, UCP2, and CPT1 mRNA expression in high fat diet-induced obese Sprague–Dawley rats
inferredcites →https://doi.org/10.1007/s11130-008-0096-6openalex-snapshot
Studies on Indian Green Leafy Vegetables for Their Antioxidant Activity
inferredcites →https://doi.org/10.1007/s11883-014-0435-zopenalex-snapshot
Inflammation and Cardiovascular Disease: From Pathogenesis to Therapeutic Target
inferredcites →https://doi.org/10.1016/0167-4889(93)90013-fopenalex-snapshot
Oxidized low-density lipoprotein enhances monocyte-endothelial cell binding against shear-stress-induced detachment
inferredcites →https://doi.org/10.1016/bs.afnr.2015.08.001openalex-snapshot
Gotu Kola (Centella asiatica)
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2004.11.016openalex-snapshot
Disruption of tumor necrosis factor-α gene diminishes the development of atherosclerosis in ApoE-deficient mice
inferredcites →https://doi.org/10.1016/j.biopha.2018.05.156openalex-snapshot
Comparison of three different extracts of Centella asiatica for anti-amnesic, antioxidant and anticholinergic activities: in vitro and in vivo study
inferredcites →https://doi.org/10.1016/j.biopha.2018.08.126openalex-snapshot
Asiatic acid protects against cisplatin-induced acute kidney injury via anti-apoptosis and anti-inflammation
inferredcites →https://doi.org/10.1016/j.bmcl.2011.01.066openalex-snapshot
A new ursane-type triterpenoid glycoside from Centella asiatica leaves modulates the production of nitric oxide and secretion of TNF-α in activated RAW 264.7 cells
inferredcites →https://doi.org/10.1016/j.cardiores.2005.01.001openalex-snapshot
Tumor necrosis factor-? promotes atherosclerotic lesion progression in APOE*3-leiden transgenic mice
inferredcites →https://doi.org/10.1016/j.cjca.2012.11.032openalex-snapshot
2012 Update of the Canadian Cardiovascular Society Guidelines for the Diagnosis and Treatment of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult
inferredcites →https://doi.org/10.1016/j.cyto.2011.12.009openalex-snapshot
GEF-H1/RhoA signalling pathway mediates lipopolysaccharide-induced intercellular adhesion molecular-1 expression in endothelial cells via activation of p38 and NF-κB
inferredcites →https://doi.org/10.1016/j.ehj.2014.11.005openalex-snapshot
C-reactive protein, inflammation and coronary heart disease
inferredcites →https://doi.org/10.1016/j.gene.2013.12.052openalex-snapshot
Cardiac-specific Traf2 overexpression enhances cardiac hypertrophy through activating AKT/GSK3β signaling
inferredcites →https://doi.org/10.1016/j.ijcard.2018.03.099openalex-snapshot
Type 1 and type 2 diabetes mellitus and incidence of seven cardiovascular diseases
inferredcites →https://doi.org/10.1016/j.intimp.2007.11.003openalex-snapshot
Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-κB inactivation in RAW 264.7 macrophages: Possible involvement of the IKK and MAPK pathways
inferredcites →https://doi.org/10.1016/j.intimp.2010.03.015openalex-snapshot
Madecassoside suppresses LPS-induced TNF-α production in cardiomyocytes through inhibition of ERK, p38, and NF-κB activity
inferredcites →https://doi.org/10.1016/j.jacc.2008.03.051openalex-snapshot
Effect of Diabetes on Progression of Coronary Atherosclerosis and Arterial Remodeling
inferredcites →https://doi.org/10.1016/j.jacl.2008.02.006openalex-snapshot
Coronary heart disease risk factors and atherosclerosis in young people
inferredcites →https://doi.org/10.1016/j.lfs.2004.09.009openalex-snapshot
Protective effect of Centella asiatica on antioxidant tissue defense system against adriamycin induced cardiomyopathy in rats
inferredcites →https://doi.org/10.1016/j.lfs.2015.07.016openalex-snapshot
The potential of asiaticoside for TGF-β1/Smad signaling inhibition in prevention and progression of hypoxia-induced pulmonary hypertension
inferredcites →https://doi.org/10.1016/j.micpath.2018.01.022openalex-snapshot
Asiatic acid inhibits LPS-induced inflammatory response in endometrial epithelial cells
inferredcites →https://doi.org/10.1016/j.numecd.2015.04.002openalex-snapshot
Centella Asiatica and Lipoic Acid, or a combination thereof, inhibit monocyte adhesion to endothelial cells from umbilical cords of gestational diabetic women
inferredcites →https://doi.org/10.1016/j.phymed.2012.09.023openalex-snapshot
Efficacy of asiatic acid, a pentacyclic triterpene on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-induced diabetic rats
inferredcites →https://doi.org/10.1016/j.phymed.2013.08.027openalex-snapshot
Antidiabetic and antihyperlipidemic activity of asiatic acid in diabetic rats, role of HMG CoA: In vivo and in silico approaches
inferredcites →https://doi.org/10.1016/j.phymed.2015.11.019openalex-snapshot
Barrier protective effect of asiatic acid in TNF-α-induced activation of human aortic endothelial cells
inferredcites →https://doi.org/10.1016/j.pop.2012.11.003openalex-snapshot
Hyperlipidemia as a Risk Factor for Cardiovascular Disease
inferredcites →https://doi.org/10.1016/j.vph.2018.08.005openalex-snapshot
Asiatic acid stabilizes cytoskeletal proteins and prevents TNF-α-induced disorganization of cell-cell junctions in human aortic endothelial cells
inferredcites →https://doi.org/10.1016/s0031-9422(00)85884-7openalex-snapshot
A reinvestigation of the triterpenes of Centella asiatica
inferredcites →https://doi.org/10.1016/s0140-6736(15)01225-8openalex-snapshot
Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis
inferredcites →https://doi.org/10.1016/s1875-5364(15)30047-9openalex-snapshot
Asiatic acid mitigates hyperglycemia and reduces islet fibrosis in Goto-Kakizaki rat, a spontaneous type 2 diabetic animal model
inferredcites →https://doi.org/10.1021/acs.jnatprod.5b01055openalex-snapshot
Natural Products as Sources of New Drugs from 1981 to 2014
inferredcites →https://doi.org/10.1038/nrm1983openalex-snapshot
Regulation of cardiac hypertrophy by intracellular signalling pathways
inferredcites →https://doi.org/10.1055/s-0029-1186142openalex-snapshot
Anti-inflammatory Effects of Madecassic Acid via the Suppression of NF-κB Pathway in LPS-Induced RAW 264.7 Macrophage Cells
inferredcites →https://doi.org/10.1055/s-0036-1594292openalex-snapshot
Variations in Echogenicity in Carotid and Femoral Atherosclerotic Plaques with Pycnogenol + Centella Asiatica Supplementation
inferredcites →https://doi.org/10.1055/s-0042-122344openalex-snapshot
Pharmacokinetics of a Standardized Extract of Centella asiatica ECa 233 in Rats
inferredcites →https://doi.org/10.1056/nejmoa013591openalex-snapshot
Endothelial Function and Oxidative Stress in Renovascular Hypertension
inferredcites →https://doi.org/10.1074/jbc.m209649200openalex-snapshot
Scavenger Receptors Class A-I/II and CD36 Are the Principal Receptors Responsible for the Uptake of Modified Low Density Lipoprotein Leading to Lipid Loading in Macrophages
inferredcites →https://doi.org/10.1079/isc.3853.20203483223openalex-snapshot
Invasive species compendium.
inferredcites →https://doi.org/10.1080/09637480500146606openalex-snapshot
Phenolic contents and antioxidant activity of some food and medicinal plants
inferredcites →https://doi.org/10.1080/13880209.2017.1318293openalex-snapshot
Centella asiatica enhances hepatic antioxidant status and regulates hepatic inflammatory cytokines in type 2 diabetic rats
inferredcites →https://doi.org/10.1080/14779072.2018.1540301openalex-snapshot
Pathophysiology of essential hypertension: an update
inferredcites →https://doi.org/10.1093/cvr/cvw186openalex-snapshot
B-cell-specific depletion of tumour necrosis factor alpha inhibits atherosclerosis development and plaque vulnerability to rupture by reducing cell death and inflammation
inferredcites →https://doi.org/10.1097/wox.0b013e3182439613openalex-snapshot
Oxidative Stress and Antioxidant Defense
inferredcites →https://doi.org/10.1155/2011/895857openalex-snapshot
Antinociceptive Activities and the Mechanisms of Anti‐Inflammation of Asiatic Acid in Mice
inferredcites →https://doi.org/10.1155/2013/152786openalex-snapshot
LOX-1, OxLDL, and Atherosclerosis
inferredcites →https://doi.org/10.1155/2013/789613openalex-snapshot
Evaluation of Analgesic and Anti-Inflammatory Activity of Chloroform and Methanol Extracts of Centella asiatica Linn
inferredcites →https://doi.org/10.1155/2014/154295openalex-snapshot
Effect ofCentella asiaticaon Oxidative Stress and Lipid Metabolism in Hyperlipidemic Animal Models
inferredcites →https://doi.org/10.1155/2016/6978936openalex-snapshot
The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation
inferredcites →https://doi.org/10.1155/2017/7023091openalex-snapshot
Centella asiatica Attenuates Mitochondrial Dysfunction and Oxidative Stress in Aβ‐Exposed Hippocampal Neurons
inferredcites →https://doi.org/10.1155/2018/2481076openalex-snapshot
Ayurvedic Medicine for the Treatment of Dementia: Mechanistic Aspects
inferredcites →https://doi.org/10.1161/01.atv.0000143933.20616.1bopenalex-snapshot
Inhibition of Tumor Necrosis Factor-α Reduces Atherosclerosis in Apolipoprotein E Knockout Mice
inferredcites →https://doi.org/10.1161/01.hyp.0000258594.87211.6bopenalex-snapshot
Measurement of Reactive Oxygen Species in Cardiovascular Studies
inferredcites →https://doi.org/10.1161/01.res.70.6.1191openalex-snapshot
Oxidized low density lipoproteins induce mRNA expression and release of endothelin from human and porcine endothelium.
inferredcites →https://doi.org/10.1161/cir.0000000000000597openalex-snapshot
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
inferredcites →https://doi.org/10.1161/circulationaha.116.022194openalex-snapshot
Clinical Update: Cardiovascular Disease in Diabetes Mellitus
inferredcites →https://doi.org/10.1161/hyp.0000000000000065openalex-snapshot
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
inferredcites →https://doi.org/10.1177/000331979004100102openalex-snapshot
Capillary Filtration and Ankle Edema in Patients with Venous Hypertension Treated with TTFCA
inferredcites →https://doi.org/10.1177/000331979004100705openalex-snapshot
Improvement of Capillary Permeability in Patients with Venous Hypertension After Treatment with TTFCA
inferredcites →https://doi.org/10.1177/2472630317751840openalex-snapshot
Pharmacological Review on Asiatic Acid and Its Derivatives: A Potential Compound
inferredcites →https://doi.org/10.1186/1472-6882-14-31openalex-snapshot
Anti-hyperglycemic activity of Centella asiatica is partly mediated by carbohydrase inhibition and glucose-fiber binding
inferredcites →https://doi.org/10.1186/s12906-016-1100-6openalex-snapshot
Asiatic acid attenuates renin-angiotensin system activation and improves vascular function in high-carbohydrate, high-fat diet fed rats
inferredcites →https://doi.org/10.1186/s12944-018-0868-4openalex-snapshot
Hypolipidemic effect of Fragarianilgerrensis Schlecht. medicine compound on hyperlipidemic rats
inferredcites →https://doi.org/10.1248/bpb.30.935openalex-snapshot
The Anti-thrombotic Active Constituents from Centella asiatica
inferredcites →https://doi.org/10.1248/bpb.31.458openalex-snapshot
Madecassoside Reduces Ischemia-Reperfusion Injury on Regional Ischemia Induced Heart Infarction in Rat
inferredcites →https://doi.org/10.1515/acph-2016-0018openalex-snapshot
Evaluation of the topical spray containing Centella asiatica extract and its efficacy on excision wounds in rats
inferredcites →https://doi.org/10.2174/157340208786241336openalex-snapshot
Role of Reactive Oxygen Species in Tumor Necrosis Factor-alpha Induced Endothelial Dysfunction
inferredcites →https://doi.org/10.2174/187221411794351833openalex-snapshot
Exploring the Role of "Brahmi" (Bacopa monnieri and Centella asiatica) in Brain Function and Therapy
inferredcites →https://doi.org/10.21767/2254-6081.100042openalex-snapshot
Medicinal Property of Gotu kola (Centella asiatica) from the Selection of Traditional Applications to the Novel Phytotherapy
inferredcites →https://doi.org/10.23736/s0026-4733.18.07666-6openalex-snapshot
Centella asiatica (Centellicum®) facilitates the regular healing of surgical scars in subjects at high risk of keloids
inferredcites →https://doi.org/10.3109/09637489309017430openalex-snapshot
Problems encountered in the community-based production of leaf concentrate as a supplement for pre-school children in Sri Lanka
inferredcites →https://doi.org/10.3389/fphar.2016.00400openalex-snapshot
In vitro and In vivo Antioxidant, Anti-hyperlipidemic Properties and Chemical Characterization of Centella asiatica (L.) Extract
inferredcites →https://doi.org/10.3390/ijms10093713openalex-snapshot
Antioxidant and Cytotoxic Activities of Centella asiatica (L) Urb.
inferredcites →https://doi.org/10.3390/molecules14103922openalex-snapshot
Pentacyclic Triterpenoids from the Medicinal Herb, Centella asiatica (L.) Urban
inferredcites →https://doi.org/10.3390/molecules16021310openalex-snapshot
Triterpene Composition and Bioactivities of Centella asiatica
inferredcites →https://doi.org/10.3390/molecules21091248openalex-snapshot
Asiatic Acid Attenuates Myocardial Ischemia/Reperfusion Injury via Akt/GSK-3β/HIF-1α Signaling in Rat H9c2 Cardiomyocytes
inferredcites →https://doi.org/10.3390/molecules23112730openalex-snapshot
Current Therapies Focused on High-Density Lipoproteins Associated with Cardiovascular Disease
inferredcites →https://doi.org/10.3390/nu6010355openalex-snapshot
Asiatic Acid Alleviates Hemodynamic and Metabolic Alterations via Restoring eNOS/iNOS Expression, Oxidative Stress, and Inflammation in Diet-Induced Metabolic Syndrome Rats
inferredcites →https://doi.org/10.3892/etm.2015.2871openalex-snapshot
Asiatic acid inhibits left ventricular remodeling and improves cardiac function in a rat model of myocardial infarction
inferredcites →https://doi.org/10.3892/ijmm.2014.1781openalex-snapshot
Asiatic acid attenuates cardiac hypertrophy by blocking transforming growth factor-β1-mediated hypertrophic signaling in vitro and in vivo
inferredcites →https://doi.org/10.3892/mmr.2017.8254openalex-snapshot
Effect of asiaticoside on endothelial cells in hypoxia‑induced pulmonary hypertension
inferredcites →https://doi.org/10.3978/j.issn.2072-1439.2015.10.41openalex-snapshot
Asiatic acid inhibits cardiac hypertrophy by blocking interleukin-1β-activated nuclear factor-κB signaling in vitro and in vivo.
inferredcites →https://doi.org/10.4103/0250-474x.78519openalex-snapshot
Pharmacological review on Centella asiatica: A potential herbal cure-all
inferredcites →https://doi.org/10.4314/ajtcam.v6i4.57206openalex-snapshot
Anti-allergic, anti-pruritic, and anti-inflammatory activities of Centella asiatica extracts
inferredcites →https://doi.org/10.7150/ijbs.14213openalex-snapshot
Asiatic Acid Protects against Cardiac Hypertrophy through Activating AMPKα Signalling Pathway
inferredcites →https://doi.org/10.7326/0003-4819-55-1-33openalex-snapshot
Factors of Risk in the Development of Coronary Heart Disease—Six-Year Follow-up Experience

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Asiaticoside attenuates oxygen–glucose deprivation/reoxygenation‐caused injury of cardiomyocytes by inhibiting autophagy
inferred← citeshttps://doi.org/10.1002/jat.4602openalex-snapshot
Asiatic acid and madecassic acid cause cardiotoxicity via inflammation and production of excessive reactive oxygen species in zebrafish
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Bridging Sustainability and Neuroscience: Biogenic Nanoparticles via Centella asiatica for Cognitive Studies
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Indigenous Knowledge and Phytochemistry: Deciphering the Healing Power of Herbal Medicine
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Impact of Temperature on Centelloside Content, Growth Characters, Physio-morphological Adaptations, and Biochemical Changes in Indian Pennywort (Centella asiatica)
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The apparent formation constants of asiatic acid and its derivatives existing in Centella asiatica with cyclodextrins by HPLC
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Centellosides: pharmaceutical applications and production enhancement strategies
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Centella asiatica extract protects against cisplatin-induced hepatotoxicity via targeting oxidative stress, inflammation, and apoptosis
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Phytochemical profiling of Thai Centella asiatica: identification of new polyacetylene glucosides and analytical considerations in HPLC-UV analysis of triterpenoids
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Simultaneous determination of four active compounds in Centella asiatica by supramolecular solvent-based extraction coupled with high performance liquid chromatography-tandem mass spectrometry
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Graph Attention Network based mapping of knowledge relations between chemical spaces of Nuclear factor kappa B and Centella asiatica
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Effect of food components on cytochrome P450 expression and activity
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Evaluation of the potential of chitosan-based films with α,β-amyrenone triterpene for wound healing
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Centella asiatica (L.) Urb. attenuates cardiac hypertrophy and improves heart function through multi-level mechanisms revealed by systems pharmacology
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Exploring the composition and properties of Centella asiatica metabolites and investigating their impact on BSA glycation, LDL oxidation and α-amylase inhibition
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Asiaticoside alleviates hypoxic pulmonary hypertension by regulating the voltage-gated potassium channel 1.5 through the protein tyrosine phosphatase non-receptor type 7 pathway
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Centella asiatica: Secondary metabolites, biological activities and biomass sources
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In silico study unravels binding potential of madecassic acid against non-structural proteins of SARS-CoV-2
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Recent insights into therapeutic potential and nanostructured carrier systems of Centella asiatica: An evidence-based review
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Simultaneous analysis of five triterpenes in Centella asiatica by high performance liquid chromatography with cyclodextrins as the mobile phase additives
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Herbal bioactive-loaded biopolymeric formulations for wound healing applications
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Asiatic acid inhibits pro-oxidant mediators-induced oxidative stress in human aortic endothelial cells
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Simple TLC-densitometric method for the quantification of asiaticoside in Centella asiatica from different origins for its standardization
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Medicinal terpenoid UDP-glycosyltransferases in plants: recent advances and research strategies
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Recent progress in the development of ursolic acid derivatives as anti‐diabetes and anti‐cardiovascular agents
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Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review
inferred← citeshttps://doi.org/10.1139/cjc-2021-0281openalex-snapshot
Anti-excitotoxicity and neuroprotective action of asiaticoside encapsulated polymeric nanoparticles in pilocarpine rodent seizure model
inferred← citeshttps://doi.org/10.1155/2021/7381620openalex-snapshot
Anti-Inflammatory and Anti-Vascular Leakage Effects by Combination of Centella asiatica and Vitis vinifera L. Leaf Extracts
inferred← citeshttps://doi.org/10.1155/2022/1015791openalex-snapshot
Targeting Nrf2‐Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals
inferred← citeshttps://doi.org/10.1155/2023/7769368openalex-snapshot
Rapid Separation of Asiatic Acid, Quercetin, and Kaempferol from Traditional Chinese Medicine Centella asiatica (L.) Urban Using HSCCC-Semi-Prep-HPLC and the Assessment of Their Potential as Fatty Acid Synthase Inhibitors
inferred← citeshttps://doi.org/10.1186/s12951-025-03946-2openalex-snapshot
Microneedle-delivered ROS-adaptive asiatic acid nanoparticles promote scarless repair via remodeling the pathological microenvironment
inferred← citeshttps://doi.org/10.1186/s13020-021-00507-1openalex-snapshot
A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Lei-gong-gen formula granule on a spontaneously hypertensive rat model
inferred← citeshttps://doi.org/10.1186/s40538-024-00615-8openalex-snapshot
RG-I-containing sugar domains from Centella Asiatica bind strongly to galectin-3 to inhibit cell–cell interactions
inferred← citeshttps://doi.org/10.12659/msm.924435openalex-snapshot
Asiaticoside Antagonizes Proliferation and Chemotherapeutic Drug Resistance in Hepatocellular Carcinoma (HCC) Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0260468openalex-snapshot
Transcriptome sequencing revealed the influence of blue light on the expression levels of light-stress response genes in Centella asiatica
inferred← citeshttps://doi.org/10.14712/fb2021067030108openalex-snapshot
Asiatic Acid Induces Mitochondrial Apoptosis via Inhibition of JAK2/STAT3 Signalling Pathway in Human Osteosarcoma
inferred← citeshttps://doi.org/10.15446/rcciquifa.v54n3.114481openalex-snapshot
Beneficial effect of Centella asiatica: Synthesis of the last 2 decades
inferred← citeshttps://doi.org/10.15575/biodjati.v8i2.21430openalex-snapshot
Effect of Chitosan-Coated Centella asiatica Nanoparticles on Kidney Histology Profile of Complicated Diabetic Mice
inferred← citeshttps://doi.org/10.21037/atm-21-6667openalex-snapshot
Asiaticoside alleviates cardiomyocyte apoptosis and oxidative stress in myocardial ischemia/reperfusion injury via activating the PI3K-AKT-GSK3β pathway in vivo and in vitro
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1099054/v1openalex-snapshot
Bioinformatics approaches to investigate the phytochemicals of Centella asiatica against the main protease of SARS-CoV-2
inferred← citeshttps://doi.org/10.21203/rs.3.rs-253571/v1openalex-snapshot
A Network Pharmacology-based Approach to Explore the Active Ingredients and Molecular Mechanism of Lei-gong-gen Formula Granule on a Spontaneously Hypertensive Rat Model
inferred← citeshttps://doi.org/10.2174/011871529x262371231009132426openalex-snapshot
Current Perspective and Mechanistic Insights on Bioactive Plant Secondary Metabolites for the Prevention and Treatment of Cardiovascular Diseases
inferred← citeshttps://doi.org/10.2174/9789815123647123020004openalex-snapshot
Sesquiterpenes: A Terpene Subclass with Multifaceted Bioactivities
inferred← citeshttps://doi.org/10.22159/ajpcr.2025v18i5.54123openalex-snapshot
NOVEL PRE-CLINICAL EVIDENCE OF CENTELLA ASIATICA AS CARDIOPROTECTIVE AGENT FOR CARDIOMYOCYTES IN AZITHROMYCIN-INDUCED RATS: A HISTOPATHOLOGICAL PERSPECTIVE
inferred← citeshttps://doi.org/10.22159/ijap.2025.v17s3.07openalex-snapshot
DESIGN AND CHARACTERIZATION OF OPTIMIZED POLYHERBAL NANOENCAPSULATION: IN VITRO ANTIOXIDANT ACTIVITY TARGETING NRF2 AND GST PATHWAYS
inferred← citeshttps://doi.org/10.24976/discov.med.202335176.28openalex-snapshot
Antifatigue Effect of Asiaticoside in Mice by Attenuating Oxidative Stress
inferred← citeshttps://doi.org/10.25259/ajbps_2_2021openalex-snapshot
Design of a Novel Bioflavonoid and Phytonutrient Enriched Formulation in Boosting Immune Competence and Sports Performance: A product Development Investigation
inferred← citeshttps://doi.org/10.26717/bjstr.2021.40.006446openalex-snapshot
"Natural Compounds and Depressive Disorder: A Review Highlighting Botanical Sources and Reaction Mechanisms"
inferred← citeshttps://doi.org/10.29137/ijerad.1674277openalex-snapshot
In Vitro Evaluation of the Antineoplastic Activity of Silver Nanoparticles Functionalized with Bioactive Molecules Against SK-MEL-30, MCF-7, and H1299 Cancer Cells
inferred← citeshttps://doi.org/10.33263/briac126.80818093openalex-snapshot
Toxicity Studies of Centella asiatica for Drug Development: Mini Review
inferred← citeshttps://doi.org/10.3389/fphys.2021.712317openalex-snapshot
Hypoxia-Induced Neuroinflammation in Alzheimer’s Disease: Potential Neuroprotective Effects of Centella asiatica
inferred← citeshttps://doi.org/10.3390/antiox9060529openalex-snapshot
Terpenoids as Potential Geroprotectors
inferred← citeshttps://doi.org/10.3390/biom11040494openalex-snapshot
Isomadecassoside, a New Ursane-Type Triterpene Glycoside from Centella asiatica Leaves, Reduces Nitrite Levels in LPS-Stimulated Macrophages
inferred← citeshttps://doi.org/10.3390/cancers16071317openalex-snapshot
Can Asiatic Acid from Centella asiatica Be a Potential Remedy in Cancer Therapy?—A Review
inferred← citeshttps://doi.org/10.3390/cells13171471openalex-snapshot
A Comprehensive Review of Cardiovascular Disease Management: Cardiac Biomarkers, Imaging Modalities, Pharmacotherapy, Surgical Interventions, and Herbal Remedies
inferred← citeshttps://doi.org/10.3390/ddc5030043openalex-snapshot
Natural Antihypertensive Drug Leads from Northeast India’s Biodiversity Hotspots: Molecular Targets, Signaling Pathways, and Safety Profiles: A Review
inferred← citeshttps://doi.org/10.3390/ijms23147740openalex-snapshot
Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part I)
inferred← citeshttps://doi.org/10.3390/life15071081openalex-snapshot
Centella asiatica: Advances in Extraction Technologies, Phytochemistry, and Therapeutic Applications
inferred← citeshttps://doi.org/10.3390/molecules28041895openalex-snapshot
Antibacterial Activity and Mechanism of Madecassic Acid against Staphylococcus aureus
inferred← citeshttps://doi.org/10.3390/molecules31122018openalex-snapshot
Multitarget Actions of Pentacyclic Triterpenic Acids in Alzheimer’s Disease: Mechanistic Insights
inferred← citeshttps://doi.org/10.3390/nu12020411openalex-snapshot
Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice
inferred← citeshttps://doi.org/10.3390/nu13113900openalex-snapshot
Beneficial Effects of Ursolic Acid and Its Derivatives—Focus on Potential Biochemical Mechanisms in Cardiovascular Conditions
inferred← citeshttps://doi.org/10.3390/nu16213709openalex-snapshot
Plant-Based Diets and Phytochemicals in the Management of Diabetes Mellitus and Prevention of Its Complications: A Review
inferred← citeshttps://doi.org/10.3390/nu18111649openalex-snapshot
Geroprotective Potential of Centella asiatica: Modulation of Cellular Aging
inferred← citeshttps://doi.org/10.3390/pharmaceutics14112532openalex-snapshot
Probing Pharmaceutical Strategies to Promote the Skin Delivery of Asiatic Acid from Hydrogels: Enhancement Effects of Organic Amine Counterions, Chemical Enhancers, and Microneedle Pretreatment
inferred← citeshttps://doi.org/10.4014/jmb.2504.04036openalex-snapshot
Enhanced Skin-Protective Effects of a Novel Centella asiatica Variety (BT-Care) Cultivated for 75 Days via Modulation of Antioxidant Defense, Collagen Synthesis, and Skin Barrier Function
inferred← citeshttps://doi.org/10.4314/tjpr.v23i4.3openalex-snapshot
Biological activity and mechanism of action of Gotu kola oil in skin wound repair
inferred← citeshttps://doi.org/10.47552/ijam.v12i3.2133openalex-snapshot
In-vitro Anti-Oxidant Property of Vallarai (Centella asiatica) cultivated by conventional and traditional Methods
inferred← citeshttps://doi.org/10.51847/9utowxppypopenalex-snapshot
Study on hydrogel eye mask with Centella asiatica L and Aloe vera L extract
inferred← citeshttps://doi.org/10.52225/narra.v4i1.697openalex-snapshot
Effect of pegagan (Centella asiatica) nanoparticle coated with chitosan on the cytokine profile of chronic diabetic mice
inferred← citeshttps://doi.org/10.5530/pj.2022.14.119openalex-snapshot
Indonesian Medicinal Plants with Anti-inflammatory Properties and Potency as Chronic Obstructive Pulmonary Disease (COPD) Herbal Medicine
inferred← citeshttps://doi.org/10.6084/m9.figshare.16779487openalex-snapshot
Additional file 1 of A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Lei-gong-gen formula granule on a spontaneously hypertensive rat model
inferred← citeshttps://doi.org/10.6084/m9.figshare.16779490openalex-snapshot
Additional file 2 of A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Lei-gong-gen formula granule on a spontaneously hypertensive rat model
inferred← citeshttps://doi.org/10.7150/ijbs.97418openalex-snapshot
The dual functions of the pentacyclic triterpenoid madecassic acid in ameliorating doxorubicin-induced cardiotoxicity and enhancing the antitumor efficacy of doxorubicin
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