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Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer

https://doi.org/10.1073/pnas.0709810105
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1 of the 35 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-21): 10.1016/s0092-8674(00)80804-1 (notice 2023-09-14).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ijc.10821openalex-snapshot
Quantification of expression of netrins, slits and their receptors in human prostate tumors
inferredcites →https://doi.org/10.1007/s00018-004-3467-7openalex-snapshot
Dependence receptors: between life and death
inferredcites →https://doi.org/10.1016/0092-8674(94)90420-0openalex-snapshot
The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6
inferredcites →https://doi.org/10.1016/j.cub.2004.05.020openalex-snapshot
Novel Role for Netrins in Regulating Epithelial Behavior during Lung Branching Morphogenesis
inferredcites →https://doi.org/10.1016/s0092-8674(00)80804-1openalex-snapshot
RETRACTED: A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion
inferredcites →https://doi.org/10.1016/s0092-8674(00)81333-1openalex-snapshot
Lessons from Hereditary Colorectal Cancer
inferredcites →https://doi.org/10.1016/s0092-8674(00)81336-7openalex-snapshot
Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor
inferredcites →https://doi.org/10.1016/s0092-8674(00)81795-xopenalex-snapshot
Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System
inferredcites →https://doi.org/10.1016/s1534-5807(03)00054-6openalex-snapshot
Netrin-1/Neogenin Interaction Stabilizes Multipotent Progenitor Cap Cells during Mammary Gland Morphogenesis
inferredcites →https://doi.org/10.1016/s1534-5807(03)00330-7openalex-snapshot
Recognition of the Neural Chemoattractant Netrin-1 by Integrins α6β4 and α3β1 Regulates Epithelial Cell Adhesion and Migration
inferredcites →https://doi.org/10.1038/27441openalex-snapshot
The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis
inferredcites →https://doi.org/10.1038/35065016openalex-snapshot
Involvement of chemokine receptors in breast cancer metastasis
inferredcites →https://doi.org/10.1038/36599openalex-snapshot
DAP kinase links the control of apoptosis to metastasis
inferredcites →https://doi.org/10.1038/386838a0openalex-snapshot
The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein
inferredcites →https://doi.org/10.1038/415530aopenalex-snapshot
Gene expression profiling predicts clinical outcome of breast cancer
inferredcites →https://doi.org/10.1038/labinvest.3700208openalex-snapshot
Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes
inferredcites →https://doi.org/10.1038/nature02788openalex-snapshot
Netrin-1 controls colorectal tumorigenesis by regulating apoptosis
inferredcites →https://doi.org/10.1038/nature03080openalex-snapshot
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
inferredcites →https://doi.org/10.1038/nature748openalex-snapshot
Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation
inferredcites →https://doi.org/10.1038/sj.cdd.4401680openalex-snapshot
Receptors that mediate cellular dependence
inferredcites →https://doi.org/10.1038/sj.emboj.7600584openalex-snapshot
The dependence receptor UNC5H2 mediates apoptosis through DAP‐kinase
inferredcites →https://doi.org/10.1053/j.gastro.2007.08.009openalex-snapshot
Inactivation of the UNC5C Netrin-1 Receptor Is Associated With Tumor Progression in Colorectal Malignancies
inferredcites →https://doi.org/10.1053/j.gastro.2007.08.074openalex-snapshot
Epigenetic and Genetic Alterations in Netrin-1 Receptors UNC5C and DCC in Human Colon Cancer
inferredcites →https://doi.org/10.1053/j.gastro.2007.10.034openalex-snapshot
Making the Case for DCC and UNC5C as Tumor-Suppressor Genes in the Colon
inferredcites →https://doi.org/10.1073/pnas.0405984101openalex-snapshot
The axonal attractant Netrin-1 is an angiogenic factor
inferredcites →https://doi.org/10.1073/pnas.0511011103openalex-snapshot
Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism
inferredcites →https://doi.org/10.1073/pnas.0701243104openalex-snapshot
The TrkC receptor induces apoptosis when the dependence receptor notion meets the neurotrophin paradigm
inferredcites →https://doi.org/10.1073/pnas.0738063100openalex-snapshot
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment
inferredcites →https://doi.org/10.1074/jbc.m302943200openalex-snapshot
Netrin Binds Discrete Subdomains of DCC and UNC5 and Mediates Interactions between DCC and Heparin
inferredcites →https://doi.org/10.1093/emboj/20.11.2715openalex-snapshot
Netrin‐1 acts as a survival factor via its receptors UNC5H and DCC
inferredcites →https://doi.org/10.1101/gad.437807openalex-snapshot
Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis
inferredcites →https://doi.org/10.1126/science.1124704openalex-snapshot
Netrins Promote Developmental and Therapeutic Angiogenesis
inferredcites →https://doi.org/10.1126/science.2294591openalex-snapshot
Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers
inferredcites →https://doi.org/10.1200/jco.2004.02.019openalex-snapshot
Role of the Dependence Receptor DCC in Colorectal Cancer Pathogenesis
inferredcites →https://doi.org/10.1200/jco.2004.08.095openalex-snapshot
Breast Cancer With Synchronous Metastases: Trends in Survival During a 14-Year Period

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4096591openalex-extracted
Targeting the Semaphorin3E/PlexinD1 in Allergic Asthma
inferred← citeshttps://doi.org/10.1002/adbi.201700178openalex-snapshot
Microfluidic Devices for Studying the Effect of Netrin‐1 on Neutrophil and Breast Cancer Cell Migration
inferred← citeshttps://doi.org/10.1002/cbdv.202500183openalex-snapshot
Folic Acid Targeted Selenium–Curcumin Nanoparticles to Enhance Apoptosis in Breast Cancer Cells
inferred← citeshttps://doi.org/10.1002/dvdy.22225openalex-snapshot
Roles for netrin signaling outside of axon guidance: A view from the worm
inferred← citeshttps://doi.org/10.1002/dvdy.22247openalex-snapshot
Cancer models in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1002/emmm.201302654openalex-snapshot
Combining chemotherapeutic agents and netrin‐1 interference potentiates cancer cell death
inferred← citeshttps://doi.org/10.1002/hep.32446openalex-snapshot
Hepatic inflammation elicits production of proinflammatory netrin‐1 through exclusive activation of translation
inferred← citeshttps://doi.org/10.1002/ijgo.15513openalex-snapshot
Expression of netrin‐1 in uterine serous carcinoma and its association with prognosis
inferred← citeshttps://doi.org/10.1002/jcp.28428openalex-snapshot
Genome‐wide analysis reveals miR‐3184‐5p and miR‐181c‐3p as a critical regulator for adipocytes‐associated breast cancer
inferred← citeshttps://doi.org/10.1002/med4.27openalex-snapshot
Crosstalk between cancer cells and the nervous system
inferred← citeshttps://doi.org/10.1002/mog2.70043openalex-snapshot
Breast Cancer Brain Metastasis: Bridging Biological Mechanisms to Therapeutic Innovations
inferred← citeshttps://doi.org/10.1007/s00018-017-2487-zopenalex-snapshot
Microbial carcinogenic toxins and dietary anti-cancer protectants
inferred← citeshttps://doi.org/10.1007/s10495-013-0923-6openalex-snapshot
The functions and regulations of DAPK in cancer metastasis
inferred← citeshttps://doi.org/10.1007/s10555-013-9459-zopenalex-snapshot
Netrin-1 as a potential target for metastatic cancer: focus on colorectal cancer
inferred← citeshttps://doi.org/10.1007/s10555-023-10095-1openalex-snapshot
The tumor-nerve circuit in breast cancer
inferred← citeshttps://doi.org/10.1007/s10620-013-3016-zopenalex-snapshot
Netrin-1 Induces Epithelial–Mesenchymal Transition and Promotes Hepatocellular Carcinoma Invasiveness
inferred← citeshttps://doi.org/10.1007/s10689-009-9288-yopenalex-snapshot
FAP-associated desmoid invasiveness correlates with in vitro resistance to doxorubicin
inferred← citeshttps://doi.org/10.1007/s10911-011-9225-1openalex-snapshot
Navigating Breast Cancer: Axon Guidance Molecules as Breast Cancer Tumor Suppressors and Oncogenes
inferred← citeshttps://doi.org/10.1007/s12032-013-0768-4openalex-snapshot
Reduced expression of Slit2 in renal cell carcinoma
inferred← citeshttps://doi.org/10.1007/s12307-014-0148-4openalex-snapshot
Microenvironmental Influences on Metastasis Suppressor Expression and Function during a Metastatic Cell’s Journey
inferred← citeshttps://doi.org/10.1007/s13105-019-00701-8openalex-snapshot
Netrin-1 promotes the collective cell migration of liver cancer cells in a 3D cell culture model
inferred← citeshttps://doi.org/10.1007/s13277-012-0532-yopenalex-snapshot
Clinical significance of UNC5B expression in bladder cancer
inferred← citeshttps://doi.org/10.1007/s13277-013-0714-2openalex-snapshot
PKCα is involved in the progression of kidney carcinoma through regulating netrin-1/UNC5B signaling pathway
inferred← citeshttps://doi.org/10.1007/s13277-016-5314-5openalex-snapshot
Targeting Netrin-1 in glioblastoma stem-like cells inhibits growth, invasion, and angiogenesis
inferred← citeshttps://doi.org/10.1016/b978-0-12-386503-8.00004-1openalex-snapshot
Guidance for Life, Cell Death, and Colorectal Neoplasia by Netrin Dependence Receptors
inferred← citeshttps://doi.org/10.1016/b978-0-12-386503-8.00005-3openalex-snapshot
A Roundabout Way to Cancer
inferred← citeshttps://doi.org/10.1016/j.bbcan.2011.04.005openalex-snapshot
The neuronal influence on tumor progression
inferred← citeshttps://doi.org/10.1016/j.bbcan.2022.188828openalex-snapshot
Crosstalk between the peripheral nervous system and breast cancer influences tumor progression
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.12.170openalex-snapshot
RETRACTED: Netrin-1 promotes metastasis of gastric cancer by regulating YAP activity
inferred← citeshttps://doi.org/10.1016/j.bbrc.2022.04.069openalex-snapshot
Inactivation of axon guidance molecule netrin-1 in human colorectal cancer by an epigenetic mechanism
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152127openalex-snapshot
Gene signatures associated with brain-topical proliferative activity in breast cancer
inferred← citeshttps://doi.org/10.1016/j.bbrep.2021.101045openalex-snapshot
Serum netrin and VCAM-1 as biomarker for Egyptian patients with type IΙ diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.bioadv.2024.213881openalex-snapshot
Anti-Netrin-1 decorated nanoparticles combined with chemotherapy for the treatment of triple-negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2017.08.036openalex-snapshot
Polymeric nanoparticles of siRNA prepared by a double-emulsion solvent-diffusion technique: Physicochemical properties, toxicity, biodistribution and efficacy in a mammary carcinoma mice model
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.110479openalex-snapshot
Development of Netrin-1-targeted peptide probes derived from the Netrin-1/DCC complex for noninvasive imaging of tumors
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.110495openalex-snapshot
Suppression of Netrin-1 attenuates angiotension II-induced cardiac remodeling through the PKC/MAPK signaling pathway
inferred← citeshttps://doi.org/10.1016/j.canlet.2021.05.034openalex-snapshot
UNC5 dependence receptor family in human cancer: A controllable double-edged sword
inferred← citeshttps://doi.org/10.1016/j.canlet.2024.217132openalex-snapshot
The intersection of the nervous system and breast cancer
inferred← citeshttps://doi.org/10.1016/j.ccell.2016.01.001openalex-snapshot
Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers
inferred← citeshttps://doi.org/10.1016/j.ccr.2013.09.010openalex-snapshot
Semaphorin 3E Suppresses Tumor Cell Death Triggered by the Plexin D1 Dependence Receptor in Metastatic Breast Cancers
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.113369openalex-snapshot
Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling
inferred← citeshttps://doi.org/10.1016/j.devcel.2009.02.006openalex-snapshot
Inhibition of Endothelial Cell Apoptosis by Netrin-1 during Angiogenesis
inferred← citeshttps://doi.org/10.1016/j.devcel.2009.06.006openalex-snapshot
Integrin Acts Upstream of Netrin Signaling to Regulate Formation of the Anchor Cell's Invasive Membrane in C. elegans
inferred← citeshttps://doi.org/10.1016/j.ejcb.2016.10.002openalex-snapshot
Netrin-1: A regulator of cancer cell motility?
inferred← citeshttps://doi.org/10.1016/j.ejmech.2011.05.047openalex-snapshot
Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine
inferred← citeshttps://doi.org/10.1016/j.ejmg.2014.04.003openalex-snapshot
Genetics of cleft lip and/or cleft palate: Association with other common anomalies
inferred← citeshttps://doi.org/10.1016/j.ejr.2022.10.003openalex-snapshot
Serum netrin-1 levels in systemic sclerosis patients with capillary abnormalities
inferred← citeshttps://doi.org/10.1016/j.gendis.2026.102329openalex-snapshot
Structural and functional insights into netrin-1 receptor binding: Therapeutic implications and clinical applications in cancer
inferred← citeshttps://doi.org/10.1016/j.heliyon.2025.e42293openalex-snapshot
The neuroscience in breast cancer: Current insights and clinical opportunities
inferred← citeshttps://doi.org/10.1016/j.jbc.2026.113262openalex-snapshot
Oncogenic KRAS represses the dependence receptor UNC5C via ERK2-FOS signaling in non-small cell lung cancer
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2015.12.011openalex-snapshot
Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response
inferred← citeshttps://doi.org/10.1016/j.jconrel.2025.114042openalex-snapshot
Antitumor efficacy achieved by targeting PEGylated nanomedicines to netrin-1 in the extracellular matrix or EphA2 on the cancer cell membrane
inferred← citeshttps://doi.org/10.1016/j.molcel.2009.02.016openalex-snapshot
Autoinhibition of UNC5b Revealed by the Cytoplasmic Domain Structure of the Receptor
inferred← citeshttps://doi.org/10.1016/j.molcel.2010.11.021openalex-snapshot
The Dependence Receptor UNC5H2/B Triggers Apoptosis via PP2A-Mediated Dephosphorylation of DAP Kinase
inferred← citeshttps://doi.org/10.1016/j.molcel.2018.08.040openalex-snapshot
The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving as a Dependence Receptor
inferred← citeshttps://doi.org/10.1016/j.molonc.2012.08.003openalex-snapshot
Multifunctional protein APPL2 contributes to survival of human glioma cells
inferred← citeshttps://doi.org/10.1016/j.pccm.2026.05.003openalex-snapshot
Molecular mechanisms and therapeutic targets in lung cancer–nerve crosstalk
inferred← citeshttps://doi.org/10.1016/j.phrs.2017.05.011openalex-snapshot
Netrins as prophylactic targets in skeletal diseases: A double-edged sword?
inferred← citeshttps://doi.org/10.1016/j.str.2010.08.011openalex-snapshot
Phosphorylation of DCC by ERK2 Is Facilitated by Direct Docking of the Receptor P1 Domain to the Kinase
inferred← citeshttps://doi.org/10.1016/j.tice.2024.102678openalex-snapshot
Netrin-1: Key insights in neural development and disorders
inferred← citeshttps://doi.org/10.1016/j.urolonc.2020.02.006openalex-snapshot
Netrin-1: A new promising diagnostic marker for muscle invasion in bladder cancer
inferred← citeshttps://doi.org/10.1017/s1470903108008353openalex-snapshot
Basic science: (March 2008)
inferred← citeshttps://doi.org/10.1021/acs.bioconjchem.3c00558openalex-snapshot
Peptide-Conjugated MRI Probe Targeted to Netrin-1, a Novel Metastatic Breast Cancer Biomarker
inferred← citeshttps://doi.org/10.1038/cdd.2009.75openalex-snapshot
Interfering with multimerization of netrin-1 receptors triggers tumor cell death
inferred← citeshttps://doi.org/10.1038/cdd.2015.100openalex-snapshot
Kremen1 and Dickkopf1 control cell survival in a Wnt-independent manner
inferred← citeshttps://doi.org/10.1038/cddis.2013.94openalex-snapshot
Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin α6β4-dependent Akt, GSK-3β, and HSF-1 in mesenchymal stem cells
inferred← citeshttps://doi.org/10.1038/cr.2015.15openalex-snapshot
CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development
inferred← citeshttps://doi.org/10.1038/labinvest.2011.126openalex-snapshot
Netrin-1 overexpression in kidney proximal tubular epithelium ameliorates cisplatin nephrotoxicity
inferred← citeshttps://doi.org/10.1038/nature10790openalex-snapshot
Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours
inferred← citeshttps://doi.org/10.1038/ncb1825openalex-snapshot
UNC-6 (netrin) orients the invasive membrane of the anchor cell in C. elegans
inferred← citeshttps://doi.org/10.1038/ncomms3790openalex-snapshot
Netrin-dependent downregulation of Frazzled/DCC is required for the dissociation of the peripodial epithelium in Drosophila
inferred← citeshttps://doi.org/10.1038/ni.2205openalex-snapshot
The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques
inferred← citeshttps://doi.org/10.1038/nm.3467openalex-snapshot
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity
inferred← citeshttps://doi.org/10.1038/nrc3005openalex-snapshot
Novel roles for Slits and netrins: axon guidance cues as anticancer targets?
inferred← citeshttps://doi.org/10.1038/onc.2010.13openalex-snapshot
Dependence receptors: a new paradigm in cell signaling and cancer therapy
inferred← citeshttps://doi.org/10.1038/onc.2014.231openalex-snapshot
Metabotropic glutamate receptor 1 acts as a dependence receptor creating a requirement for glutamate to sustain the viability and growth of human melanomas
inferred← citeshttps://doi.org/10.1038/s41388-025-03420-1openalex-snapshot
Multiple anti-tumor programs are activated by blocking BAD phosphorylation
inferred← citeshttps://doi.org/10.1038/s41416-022-01921-4openalex-snapshot
Somatic mutations in DCC are associated with genomic instability and favourable outcomes in melanoma patients treated with immune checkpoint inhibitors
inferred← citeshttps://doi.org/10.1038/s41418-017-0012-4openalex-snapshot
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
inferred← citeshttps://doi.org/10.1038/s41418-023-01209-xopenalex-snapshot
Netrin-1 blockade inhibits tumor associated Myeloid-derived suppressor cells, cancer stemness and alleviates resistance to chemotherapy and immune checkpoint inhibitor
inferred← citeshttps://doi.org/10.1038/s41419-018-1094-8openalex-snapshot
Comparison of breast cancer metastasis models reveals a possible mechanism of tumor aggressiveness
inferred← citeshttps://doi.org/10.1038/s41420-019-0175-5openalex-snapshot
Kremen1-induced cell death is regulated by homo- and heterodimerization
inferred← citeshttps://doi.org/10.1038/s41586-023-06367-zopenalex-snapshot
Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer
inferred← citeshttps://doi.org/10.1038/s41586-023-06372-2openalex-snapshot
Pharmacological targeting of netrin-1 inhibits EMT in cancer
inferred← citeshttps://doi.org/10.1038/s41598-017-05707-0openalex-snapshot
Netrin-1 promotes glioma growth by activating NF-κB via UNC5A
inferred← citeshttps://doi.org/10.1038/s41598-021-87949-7openalex-snapshot
Netrin-1 functions as a suppressor of bone morphogenetic protein (BMP) signaling
inferred← citeshttps://doi.org/10.1038/s41598-025-91559-yopenalex-snapshot
Semaphorin 3F inhibits breast cancer metastasis by regulating the Akt-mTOR and TGFβ signaling pathways via neuropilin-2
inferred← citeshttps://doi.org/10.1038/s41598-025-94589-8openalex-snapshot
A stable NTN1 fluorescent reporter chicken reveals cell specific molecular signatures during optic fissure closure
inferred← citeshttps://doi.org/10.1042/bcj20260374openalex-snapshot
Netrin-1 and UNC5H receptors: role in cell fate determination and carcinogenesis
inferred← citeshttps://doi.org/10.1051/medsci/20163203005openalex-snapshot
Le facteur nétrine-1 régule la reprogrammation cellulaire vers l’état pluripotent
inferred← citeshttps://doi.org/10.1051/medsci/2023207openalex-snapshot
Cibler la nétrine-1 pour inhiber la transition épithélio-mésenchymateuse
inferred← citeshttps://doi.org/10.1053/j.gastro.2008.06.080openalex-snapshot
NF-κB Regulates Netrin-1 Expression and Affects the Conditional Tumor Suppressive Activity of the Netrin-1 Receptors
inferred← citeshttps://doi.org/10.1053/j.gastro.2009.12.061openalex-snapshot
Netrin-1 Mediates Early Events in Pancreatic Adenocarcinoma Progression, Acting on Tumor and Endothelial Cells
inferred← citeshttps://doi.org/10.1073/pnas.0803645105openalex-snapshot
Netrin-1 is a survival factor during commissural neuron navigation
inferred← citeshttps://doi.org/10.1073/pnas.1212333110openalex-snapshot
Dependence receptor TrkC is a putative colon cancer tumor suppressor
inferred← citeshttps://doi.org/10.1073/pnas.2103319118openalex-snapshot
Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity
inferred← citeshttps://doi.org/10.1074/jbc.m112.397398openalex-snapshot
Netrin-1 Promotes Glioblastoma Cell Invasiveness and Angiogenesis by Multiple Pathways Including Activation of RhoA, Cathepsin B, and cAMP-response Element-binding Protein
inferred← citeshttps://doi.org/10.1080/15384047.2018.1529109openalex-snapshot
Serine protease modulation of Dependence Receptors and EMT protein expression
inferred← citeshttps://doi.org/10.1083/jcb.201301091openalex-snapshot
The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo
inferred← citeshttps://doi.org/10.1084/jem.20082299openalex-snapshot
Netrin-1 acts as a survival factor for aggressive neuroblastoma
inferred← citeshttps://doi.org/10.1089/mab.2013.0077openalex-snapshot
An Uncoordinated-5 Homolog B Receptor Monoclonal Antibody Regulates A375 Melanoma Cell Migration
inferred← citeshttps://doi.org/10.1091/mbc.e09-12-1011openalex-snapshot
Cdo Interacts with APPL1 and Activates AKT in Myoblast Differentiation
inferred← citeshttps://doi.org/10.1093/jnci/djn491openalex-snapshot
Interference With Netrin-1 and Tumor Cell Death in Non–Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.1093/jnci/djv208openalex-snapshot
Unraveling the Role of Huntingtin in Breast Cancer Metastasis
inferred← citeshttps://doi.org/10.1093/toxsci/kfaa041openalex-snapshot
Late Protective Effect of Netrin-1 in the Murine Acetaminophen Hepatotoxicity Model
inferred← citeshttps://doi.org/10.1097/cco.0b013e328333dcd1openalex-snapshot
Netrin-1 and its dependence receptors as original targets for cancer therapy
inferred← citeshttps://doi.org/10.1097/cco.0b013e328334b4d9openalex-snapshot
Current World Literature
inferred← citeshttps://doi.org/10.1101/2020.05.30.125260openalex-snapshot
Stagewise identification of significantly mutated and dysregulated gene clusters in major molecular classes of breast invasive carcinoma
inferred← citeshttps://doi.org/10.1101/2023.10.26.563740openalex-snapshot
Interactions of netrin-1 through its glycosylation sites immobilize Deleted in Colorectal Cancer (DCC) by favoring its constitutive clustering
inferred← citeshttps://doi.org/10.1101/2024.10.01.616014openalex-snapshot
A stable Netrin-1 fluorescent reporter chicken reveals cell-specific molecular signatures during optic fissure closure
inferred← citeshttps://doi.org/10.1111/febs.14507openalex-snapshot
Dependence receptors – the dark side awakens
inferred← citeshttps://doi.org/10.1111/jcmm.12939openalex-snapshot
CD151 mediates netrin‐1‐induced angiogenesis through the Src‐FAK‐Paxillin pathway
inferred← citeshttps://doi.org/10.1111/jcmm.18241openalex-snapshot
Research progress of the netrins and their receptors in cancer
inferred← citeshttps://doi.org/10.1126/scisignal.2001521openalex-snapshot
Dependence Receptors: From Basic Research to Drug Development
inferred← citeshttps://doi.org/10.1126/scisignal.2002456openalex-snapshot
Nucleolar Localization of a Netrin-1 Isoform Enhances Tumor Cell Proliferation
inferred← citeshttps://doi.org/10.1128/jvi.02187-19openalex-snapshot
Polyomavirus Small T Antigen Induces Apoptosis in Mammalian Cells through the UNC5B Pathway in a PP2A-Dependent Manner
inferred← citeshttps://doi.org/10.1128/mcb.00378-10openalex-snapshot
Rb/E2F Regulates Expression of Neogenin during Neuronal Migration
inferred← citeshttps://doi.org/10.1136/gutjnl-2013-306704openalex-snapshot
Dependence receptors and colorectal cancer
inferred← citeshttps://doi.org/10.1136/jim-2021-001785openalex-snapshot
Diagnostic Efficacy of Serum and Urinary Netrin-1 in the Early Detection of Diabetic Nephropathy
inferred← citeshttps://doi.org/10.1152/ajprenal.90686.2008openalex-snapshot
Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor
inferred← citeshttps://doi.org/10.1155/2014/901941openalex-snapshot
Netrins and Their Roles in Placental Angiogenesis
inferred← citeshttps://doi.org/10.1155/2019/3947123openalex-snapshot
Netrin Family: Role for Protein Isoforms in Cancer
inferred← citeshttps://doi.org/10.1155/2022/5887671openalex-snapshot
Oleanolic Acid (OA) Targeting UNC5B Inhibits Proliferation and EMT of Ovarian Cancer Cell and Increases Chemotherapy Sensitivity of Niraparib
inferred← citeshttps://doi.org/10.1158/0008-5472.can-13-3116openalex-snapshot
Netrin-1 Promotes Medulloblastoma Cell Invasiveness and Angiogenesis, and Demonstrates Elevated Expression in Tumor Tissue and Urine of Patients with Pediatric Medulloblastoma
inferred← citeshttps://doi.org/10.1158/0008-5472.can-14-3652openalex-snapshot
Dependence Receptors and Cancer: Addiction to Trophic Ligands
inferred← citeshttps://doi.org/10.1158/0008-5472.can-18-1590openalex-snapshot
Netrin-1 and Its Receptor DCC Are Causally Implicated in Melanoma Progression
inferred← citeshttps://doi.org/10.1158/0008-5472.can-18-2952openalex-snapshot
Cancer-Associated Fibroblasts Produce Netrin-1 to Control Cancer Cell Plasticity
inferred← citeshttps://doi.org/10.1158/0008-5472.can-18-3995openalex-snapshot
Exosomal Induction of Tumor Innervation
inferred← citeshttps://doi.org/10.1158/0008-5472.can-19-1340openalex-snapshot
Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis
inferred← citeshttps://doi.org/10.1158/0008-5472.can-20-2793openalex-snapshot
Cancer-Associated Neurogenesis and Nerve-Cancer Cross-talk
inferred← citeshttps://doi.org/10.1158/2326-6066.cir-22-0658openalex-snapshot
Netrin-1 Promotes the Immunosuppressive Activity of MDSCs in Colorectal Cancer
inferred← citeshttps://doi.org/10.1158/2767-9764.crc-24-0101openalex-snapshot
Netrin-1 and UNC5B Cooperate with Integrins to Mediate YAP-Driven Cytostasis
inferred← citeshttps://doi.org/10.1159/000324474openalex-snapshot
Netrin-1 Overexpression in Oxygen-Induced Retinopathy Correlates with Breakdown of the Blood-Retina Barrier and Retinal Neovascularization
inferred← citeshttps://doi.org/10.1167/iovs.11-8722openalex-snapshot
Netrin-1 Simultaneously Suppresses Corneal Inflammation and Neovascularization
inferred← citeshttps://doi.org/10.1177/1010428317698388openalex-snapshot
Netrin-1 in cancer: Potential biomarker and therapeutic target?
inferred← citeshttps://doi.org/10.1177/1010428317705508openalex-snapshot
The role of Sox6 and Netrin-1 in ovarian cancer cell growth, invasiveness, and angiogenesis
inferred← citeshttps://doi.org/10.1177/1724600820985528openalex-snapshot
Long non-coding RNA PITPNA-AS1 regulates UNC5B expression in papillary thyroid cancer via sponging miR-129-5p
inferred← citeshttps://doi.org/10.1186/1471-213x-11-41openalex-snapshot
The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor
inferred← citeshttps://doi.org/10.1186/1471-2407-14-93openalex-snapshot
PKC α regulates netrin-1/UNC5B-mediated survival pathway in bladder cancer
inferred← citeshttps://doi.org/10.1186/1477-7819-12-352openalex-snapshot
Neogenin expression is inversely associated with breast cancer grade in ex vivo
inferred← citeshttps://doi.org/10.1186/s12882-016-0260-4openalex-snapshot
Netrin-1 attenuates the progression of renal dysfunction by blocking endothelial-to-mesenchymal transition in the 5/6 nephrectomy rat model
inferred← citeshttps://doi.org/10.1186/s12885-016-2922-9openalex-snapshot
Overexpression of UNC5B in bladder cancer cells inhibits proliferation and reduces the volume of transplantation tumors in nude mice
inferred← citeshttps://doi.org/10.1186/s12964-022-00935-yopenalex-snapshot
Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis
inferred← citeshttps://doi.org/10.1186/s12964-025-02489-1openalex-snapshot
Netrin-1-UNC5B/neogenin axis enhances the stemness of colorectal cancer cells
inferred← citeshttps://doi.org/10.1186/s13046-016-0482-0openalex-snapshot
Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness
inferred← citeshttps://doi.org/10.1186/s13058-018-0963-5openalex-snapshot
Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis
inferred← citeshttps://doi.org/10.1242/dev.029330openalex-snapshot
Cross-repressive interactions betweenLrig3and netrin 1 shape the architecture of the inner ear
inferred← citeshttps://doi.org/10.1242/dev.144519openalex-snapshot
Distinct functions for netrin 1 in chicken and murine semicircular canal morphogenesis
inferred← citeshttps://doi.org/10.1242/jcs.120022openalex-snapshot
Netrin-1 induced activation of Notch signaling mediates glioblastoma cell invasion
inferred← citeshttps://doi.org/10.1267/ahc.17035openalex-snapshot
Expression of Draxin in Lung Carcinomas
inferred← citeshttps://doi.org/10.1369/jhc.2009.953463openalex-snapshot
Characterization and Expression of Netrin-1 and Its Receptors UNC5B and DCC in Human Placenta
inferred← citeshttps://doi.org/10.1371/journal.pbio.1002421openalex-snapshot
Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus
inferred← citeshttps://doi.org/10.1371/journal.pgen.1005905openalex-snapshot
SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane
inferred← citeshttps://doi.org/10.1371/journal.pone.0038074openalex-snapshot
Down-Regulation of Neogenin Accelerated Glioma Progression through Promoter Methylation and Its Overexpression in SHG-44 Induced Apoptosis
inferred← citeshttps://doi.org/10.1371/journal.pone.0039540openalex-snapshot
Blocking Fibroblast Growth Factor Receptor Signaling Inhibits Tumor Growth, Lymphangiogenesis, and Metastasis
inferred← citeshttps://doi.org/10.1371/journal.pone.0092311openalex-snapshot
Netrin-1 Expression Is an Independent Prognostic Factor for Poor Patient Survival in Brain Metastases
inferred← citeshttps://doi.org/10.1371/journal.pone.0118854openalex-snapshot
ABL Tyrosine Kinase Inhibition Variable Effects on the Invasive Properties of Different Triple Negative Breast Cancer Cell Lines
inferred← citeshttps://doi.org/10.1517/14728222.12.8.995openalex-snapshot
Netrin-1 and its receptors in tumour growth promotion
inferred← citeshttps://doi.org/10.1517/14728222.2011.575361openalex-snapshot
Targeting neurotrophin-3 and its dependence receptor tyrosine kinase receptor C: a new antitumoral strategy
inferred← citeshttps://doi.org/10.15252/emmm.201505480openalex-snapshot
Targeting netrin‐1/DCC interaction in diffuse large B‐cell and mantle cell lymphomas
inferred← citeshttps://doi.org/10.15252/emmm.201505945openalex-snapshot
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin‐1 interference
inferred← citeshttps://doi.org/10.15252/emmm.202114495openalex-snapshot
Dependence receptors: new targets for cancer therapy
inferred← citeshttps://doi.org/10.15252/emmm.202216732openalex-snapshot
From netrin‐1‐targeted SPECT/CT to internal radiotherapy for management of advanced solid tumors
inferred← citeshttps://doi.org/10.1684/bdc.2013.1858openalex-snapshot
Les récepteurs à dépendance : carrefours entre vie et mort
inferred← citeshttps://doi.org/10.18632/aging.103639openalex-snapshot
High expression of UNC5B enhances tumor proliferation, increases metastasis, and worsens prognosis in breast cancer
inferred← citeshttps://doi.org/10.18632/oncotarget.17750openalex-snapshot
Netrin-1 promotes gastric cancer cell proliferation and invasion via the receptor neogenin through PI3K/AKT signaling pathway
inferred← citeshttps://doi.org/10.18632/oncotarget.25201openalex-snapshot
The role of netrin-1 in metastatic renal cell carcinoma treated with sunitinib
inferred← citeshttps://doi.org/10.18632/oncotarget.258openalex-snapshot
Netrin-1 overexpression is predictive of ovarian malignancies
inferred← citeshttps://doi.org/10.18632/oncotarget.3400openalex-snapshot
Netrin-4 as a biomarker promotes cell proliferation and invasion in gastric cancer
inferred← citeshttps://doi.org/10.18632/oncotarget.3746openalex-snapshot
Peritoneal tumor spread in serous ovarian cancer-epithelial mesenchymal status and outcome
inferred← citeshttps://doi.org/10.18632/oncotarget.5668openalex-snapshot
MUC4-promoted neural invasion is mediated by the axon guidance factor netrin-1 in PDAC
inferred← citeshttps://doi.org/10.18632/oncotarget.6543openalex-snapshot
Differential expression of neurogenes among breast cancer subtypes identifies high risk patients
inferred← citeshttps://doi.org/10.18632/oncotarget.9024openalex-snapshot
Genetic association of deleted in colorectal carcinoma variants with breast cancer risk: A case-control study
inferred← citeshttps://doi.org/10.21037/atm-20-2161openalex-snapshot
Macrophage-derived netrin-1 contributes to endometriosis- associated pain
inferred← citeshttps://doi.org/10.21037/atm-21-5560openalex-snapshot
Netrin-1 promotes retinoblastoma-associated angiogenesis
inferred← citeshttps://doi.org/10.21203/rs.2.17387/v1openalex-snapshot
Macrophage-derived Netrin-1 participates in endometriosis-associated pain
inferred← citeshttps://doi.org/10.2147/cmar.s551516openalex-snapshot
Relationship Between Netrin-1 Staining and Neoadjuvant Treatment Response in HER2-Positive Locally Advanced Breast Cancer
inferred← citeshttps://doi.org/10.2174/0113816128402718250806151308openalex-snapshot
Exploring the Neurobiological Mechanisms of Cancer Growth
inferred← citeshttps://doi.org/10.2174/156802609789630820openalex-snapshot
Systemic Delivery and Quantification of Unformulated Interfering RNAs In Vivo
inferred← citeshttps://doi.org/10.2174/2210309011202030202openalex-snapshot
Role of Netrin-1 Beyond the Brain: From Biomarker of Tissue Injury to Therapy for Inflammatory Diseases
inferred← citeshttps://doi.org/10.2217/bmm-2019-0056openalex-snapshot
Neural Activities Are Unfavorable for the Prognosis of Ovarian Cancer Through Mrna Expression Analysis
inferred← citeshttps://doi.org/10.22391/fppc.467700openalex-snapshot
Relationship of serum netrin-1 levels with breast masses
inferred← citeshttps://doi.org/10.2353/ajpath.2009.090224openalex-snapshot
Netrin-1 Overexpression Protects Kidney from Ischemia Reperfusion Injury by Suppressing Apoptosis
inferred← citeshttps://doi.org/10.25100/cm.v49i2.3011openalex-snapshot
Netrin 1 and Alpha-Methyl Acylcoenzim-A Racemase in diagnosis of prostate cancer
inferred← citeshttps://doi.org/10.3109/1354750x.2010.541564openalex-snapshot
Plasma netrin-1 is a diagnostic biomarker of human cancers
inferred← citeshttps://doi.org/10.3109/1354750x.2012.709882openalex-snapshot
Netrin-1 concentrations in patients with advanced gastric cancer and its relation with treatment
inferred← citeshttps://doi.org/10.33696/gynaecology.4.051openalex-snapshot
Netrin-1 Expression in Uterine Serous Carcinoma and Its Association with Prognosis
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1859845openalex-snapshot
Neural regulation of immune evasion in breast cancer: a multiscale neuro–immune framework
inferred← citeshttps://doi.org/10.3389/fnagi.2020.507140openalex-snapshot
Senescent Cell-Secreted Netrin-1 Modulates Aging-Related Disorders by Recruiting Sympathetic Fibers
inferred← citeshttps://doi.org/10.3389/fnmol.2024.1379726openalex-snapshot
Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases
inferred← citeshttps://doi.org/10.3389/fonc.2020.00094openalex-snapshot
Dependence and Guidance Receptors—DCC and Neogenin—In Partial EMT and the Actions of Serine Proteases
inferred← citeshttps://doi.org/10.3389/fphys.2018.01662openalex-snapshot
Semaphorin 3F and Netrin-1: The Novel Function as a Regulator of Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/biom12070901openalex-snapshot
Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network
inferred← citeshttps://doi.org/10.3390/cancers12061555openalex-snapshot
Proteomic Profiling of Retinoblastoma-Derived Exosomes Reveals Potential Biomarkers of Vitreous Seeding
inferred← citeshttps://doi.org/10.3390/cancers15041038openalex-snapshot
Increased Expression Levels of Netrin-1 in Visceral Adipose Tissue during Obesity Favour Colon Cancer Cell Migration
inferred← citeshttps://doi.org/10.3390/cimb46070422openalex-snapshot
Mechanism of DAPK1 for Regulating Cancer Stem Cells in Thyroid Cancer
inferred← citeshttps://doi.org/10.3390/vetsci9090494openalex-snapshot
Implication of Netrin-1 Gain of Expression in Canine Nodal Lymphoma
inferred← citeshttps://doi.org/10.3410/f.1147380.619269openalex-snapshot
Faculty Opinions recommendation of UNC-6 (netrin) orients the invasive membrane of the anchor cell in C. elegans.
inferred← citeshttps://doi.org/10.3892/ijo.2019.4931openalex-snapshot
UNC5C‑knockdown enhances the growth and metastasis of breast cancer cells by potentiating the integrin�α6/β4 signaling pathway
inferred← citeshttps://doi.org/10.3892/or.2018.6614openalex-snapshot
Netrin‑1 induces the proliferation of gastric cancer cells via the ERK/MAPK signaling pathway and FAK activation
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